TreeWAS – Variant ID: rs117483990

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K70.9 Alcoholic liver disease, unspecified	0.006	0.994	0.000
K70 Alcoholic liver disease	0.005	0.995	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
K70.1 Alcoholic hepatitis	0.004	0.996	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.004	0.996	0.000
D17 Benign lipomatous neoplasm	0.004	0.996	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.004	0.996	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.003	0.996	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.003	0.996	0.000
K70.0 Alcoholic fatty liver	0.003	0.996	0.000
K70.3 Alcoholic cirrhosis of liver	0.003	0.996	0.000
N13.3 Other and unspecified hydronephrosis	0.003	0.997	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.003	0.997	0.000
K70-K77 Diseases of liver	0.003	0.997	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.003	0.997	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.003	0.997	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.003	0.997	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.997	0.003
T84.0 Mechanical complication of internal joint prosthesis	0.003	0.997	0.000
D25 Leiomyoma of uterus	0.003	0.997	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.003	0.997	0.000
K73 Chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.003	0.997	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.003	0.997	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.003	0.997	0.000
K76 Other diseases of liver	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.003	0.997	0.000
Z88.6 Personal history of allergy to analgesic agent	0.000	0.997	0.003
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.003	0.997	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.003	0.997	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.003	0.997	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.003	0.997	0.000
D10-D36 Benign neoplasms	0.003	0.997	0.000
D18.0 Haemangioma, any site	0.003	0.997	0.000
K73.9 Chronic hepatitis, unspecified	0.003	0.997	0.000
D18 Haemangioma and lymphangioma, any site	0.003	0.997	0.000
I25.2 Old myocardial infarction	0.000	0.997	0.003
D23 Other benign neoplasms of skin	0.003	0.997	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.003	0.997	0.000
H26.9 Cataract, unspecified	0.003	0.997	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.003	0.997	0.000
K76.6 Portal hypertension	0.003	0.997	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.003	0.997	0.000
D23.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.997	0.003
Z88.2 Personal history of allergy to sulphonamides	0.000	0.997	0.003
D25.1 Intramural leiomyoma of uterus	0.003	0.997	0.000
C78.0 Secondary malignant neoplasm of lung	0.003	0.997	0.000
D23.1 Skin of eyelid, including canthus	0.003	0.997	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.003	0.997	0.000
D23.7 Skin of lower limb, including hip	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
K77 Liver disorders in diseases classified elsewhere	0.003	0.997	0.000
K75 Other inflammatory liver diseases	0.003	0.997	0.000
K72 Hepatic failure, not elsewhere classified	0.003	0.997	0.000
K71 Toxic liver disease	0.003	0.997	0.000
C78.7 Secondary malignant neoplasm of liver	0.003	0.997	0.000
D25.2 Subserosal leiomyoma of uterus	0.003	0.997	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.003	0.997	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.000	0.997	0.003
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.003	0.997	0.000
Z88.5 Personal history of allergy to narcotic agent	0.000	0.997	0.003
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.997	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.997	0.000
C80 Malignant neoplasm without specification of site	0.002	0.997	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.002	0.997	0.000
K76.8 Other specified diseases of liver	0.002	0.997	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.002	0.997	0.000
N13 Obstructive and reflux uropathy	0.003	0.997	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.002	0.997	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.002	0.997	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.002	0.997	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.002	0.997	0.000
K76.7 Hepatorenal syndrome	0.002	0.997	0.000
K76.5 Hepatic veno-occlusive disease	0.002	0.997	0.000
K76.4 Peliosis hepatis	0.002	0.997	0.000
K76.3 Infarction of liver	0.002	0.997	0.000
K76.2 Central haemorrhagic necrosis of liver	0.002	0.997	0.000
K76.1 Chronic passive congestion of liver	0.002	0.997	0.000
D13.1 Stomach	0.002	0.998	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.998	0.002
D32 Benign neoplasm of meninges	0.002	0.998	0.000
D31 Benign neoplasm of eye and adnexa	0.002	0.998	0.000
D30 Benign neoplasm of urinary organs	0.002	0.998	0.000
D29 Benign neoplasm of male genital organs	0.002	0.998	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.002	0.998	0.000
D26 Other benign neoplasms of uterus	0.002	0.998	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.002	0.998	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.002	0.998	0.000
D19 Benign neoplasm of mesothelial tissue	0.002	0.998	0.000
D16 Benign neoplasm of bone and articular cartilage	0.002	0.998	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.002	0.998	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.002	0.998	0.000
D10 Benign neoplasm of mouth and pharynx	0.002	0.998	0.000
D34 Benign neoplasm of thyroid gland	0.002	0.998	0.000
D18.1 Lymphangioma, any site	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.998	0.002
D27 Benign neoplasm of ovary	0.002	0.998	0.000
D23.9 Skin, unspecified	0.002	0.998	0.000
D23.2 Skin of ear and external auricular canal	0.002	0.998	0.000
D23.0 Skin of lip	0.002	0.998	0.000
K76.9 Liver disease, unspecified	0.002	0.998	0.000
D36 Benign neoplasm of other and unspecified sites	0.002	0.998	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.002	0.998	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.002	0.998	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.002	0.998	0.000
C78.2 Secondary malignant neoplasm of pleura	0.002	0.998	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.002	0.998	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.002	0.998	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
D23.4 Skin of scalp and neck	0.002	0.998	0.000
D11 Benign neoplasm of major salivary glands	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.002	0.998	0.000
D25.9 Leiomyoma of uterus, unspecified	0.002	0.998	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.002	0.998	0.000
D13.9 Ill-defined sites within the digestive system	0.002	0.998	0.000
D13.7 Endocrine pancreas	0.002	0.998	0.000
D13.6 Pancreas	0.002	0.998	0.000
D13.5 Extrahepatic bile ducts	0.002	0.998	0.000
D13.4 Liver	0.002	0.998	0.000
D13.3 Other and unspecified parts of small intestine	0.002	0.998	0.000
D13.2 Duodenum	0.002	0.998	0.000
D13.0 Oesophagus	0.002	0.998	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
K74.4 Secondary biliary cirrhosis	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.002	0.998	0.000
K74.1 Hepatic sclerosis	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.002	0.998	0.000
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
K71.9 Toxic liver disease, unspecified	0.002	0.998	0.000
K71.8 Toxic liver disease with other disorders of liver	0.002	0.998	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.002	0.998	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.002	0.998	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.002	0.998	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.002	0.998	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.002	0.998	0.000
K71.2 Toxic liver disease with acute hepatitis	0.002	0.998	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.002	0.998	0.000
K71.0 Toxic liver disease with cholestasis	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
K72.1 Chronic hepatic failure	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.002	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.002	0.998	0.000
K75.4 Autoimmune hepatitis	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.002	0.998	0.000
K75.1 Phlebitis of portal vein	0.002	0.998	0.000
K75.0 Abscess of liver	0.002	0.998	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.002	0.998	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
C77.4 Inguinal and lower limb lymph nodes	0.002	0.998	0.000
D33.3 Cranial nerves	0.002	0.998	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.998	0.002
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.998	0.002
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.998	0.002
D24 Benign neoplasm of breast	0.002	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T87 Complications peculiar to reattachment and amputation	0.002	0.998	0.000
T86 Failure and rejection of transplanted organs and tissues	0.002	0.998	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.002	0.998	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.002	0.998	0.000
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
C79 Secondary malignant neoplasm of other sites	0.002	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
D23.5 Skin of trunk	0.002	0.998	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.002	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.002	0.998	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.002	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
D33.9 Central nervous system, unspecified	0.002	0.998	0.000
D33.7 Other specified parts of central nervous system	0.002	0.998	0.000
D33.4 Spinal cord	0.002	0.998	0.000
D33.2 Brain, unspecified	0.002	0.998	0.000
D33.1 Brain, infratentorial	0.002	0.998	0.000
D33.0 Brain, supratentorial	0.002	0.998	0.000
D35.2 Pituitary gland	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.998	0.000
N13.6 Pyonephrosis	0.002	0.998	0.000
N13.4 Hydroureter	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
D23.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
D35.9 Endocrine gland, unspecified	0.002	0.998	0.000
D35.8 Pluriglandular involvement	0.002	0.998	0.000
D35.7 Other specified endocrine glands	0.002	0.998	0.000
D35.6 Aortic body and other paraganglia	0.002	0.998	0.000
D35.5 Carotid body	0.002	0.998	0.000
D35.4 Pineal gland	0.002	0.998	0.000
D35.3 Craniopharyngeal duct	0.002	0.998	0.000
D35.1 Parathyroid gland	0.002	0.998	0.000
D35.0 Adrenal gland	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.002	0.998	0.000
D10.9 Pharynx, unspecified	0.002	0.998	0.000
D10.7 Hypopharynx	0.002	0.998	0.000
D10.6 Nasopharynx	0.002	0.998	0.000
D10.5 Other parts of oropharynx	0.002	0.998	0.000
D10.4 Tonsil	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.002	0.998	0.000
D10.2 Floor of mouth	0.002	0.998	0.000
D10.1 Tongue	0.002	0.998	0.000
D10.0 Lip	0.002	0.998	0.000
D14.4 Respiratory system, unspecified	0.002	0.998	0.000
D14.3 Bronchus and lung	0.002	0.998	0.000
D14.2 Trachea	0.002	0.998	0.000
D14.1 Larynx	0.002	0.998	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.002	0.998	0.000
D15.9 Intrathoracic organ, unspecified	0.002	0.998	0.000
D15.7 Other specified intrathoracic organs	0.002	0.998	0.000
D15.2 Mediastinum	0.002	0.998	0.000
D15.1 Heart	0.002	0.998	0.000
D15.0 Thymus	0.002	0.998	0.000
D16.9 Bone and articular cartilage, unspecified	0.002	0.998	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.002	0.998	0.000
D16.7 Ribs, sternum and clavicle	0.002	0.998	0.000
D16.6 Vertebral column	0.002	0.998	0.000
D16.5 Lower jaw bone	0.002	0.998	0.000
D16.4 Bones of skull and face	0.002	0.998	0.000
D16.3 Short bones of lower limb	0.002	0.998	0.000
D16.2 Long bones of lower limb	0.002	0.998	0.000
D16.1 Short bones of upper limb	0.002	0.998	0.000
D16.0 Scapula and long bones of upper limb	0.002	0.998	0.000
D19.9 Mesothelial tissue, unspecified	0.002	0.998	0.000
D19.7 Mesothelial tissue of other sites	0.002	0.998	0.000
D19.1 Mesothelial tissue of peritoneum	0.002	0.998	0.000
D19.0 Mesothelial tissue of pleura	0.002	0.998	0.000
D20.1 Peritoneum	0.002	0.998	0.000
D20.0 Retroperitoneum	0.002	0.998	0.000
D21.9 Connective and other soft tissue, unspecified	0.002	0.998	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.002	0.998	0.000
D21.5 Connective and other soft tissue of pelvis	0.002	0.998	0.000
D21.4 Connective and other soft tissue of abdomen	0.002	0.998	0.000
D21.3 Connective and other soft tissue of thorax	0.002	0.998	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
D26.9 Uterus, unspecified	0.002	0.998	0.000
D26.7 Other parts of uterus	0.002	0.998	0.000
D26.1 Corpus uteri	0.002	0.998	0.000
D26.0 Cervix uteri	0.002	0.998	0.000
D28.9 Female genital organ, unspecified	0.002	0.998	0.000
D28.7 Other specified female genital organs	0.002	0.998	0.000
D28.2 Uterine tubes and ligaments	0.002	0.998	0.000
D28.1 Vagina	0.002	0.998	0.000
D28.0 Vulva	0.002	0.998	0.000
D29.9 Male genital organ, unspecified	0.002	0.998	0.000
D29.7 Other male genital organs	0.002	0.998	0.000
D29.4 Scrotum	0.002	0.998	0.000
D29.3 Epididymis	0.002	0.998	0.000
D29.2 Testis	0.002	0.998	0.000
D29.1 Prostate	0.002	0.998	0.000
D29.0 Penis	0.002	0.998	0.000
D30.9 Urinary organ, unspecified	0.002	0.998	0.000
D30.7 Other urinary organs	0.002	0.998	0.000
D30.4 Urethra	0.002	0.998	0.000
D30.3 Bladder	0.002	0.998	0.000
D30.2 Ureter	0.002	0.998	0.000
D30.1 Renal pelvis	0.002	0.998	0.000
D30.0 Kidney	0.002	0.998	0.000
D31.9 Eye, unspecified	0.002	0.998	0.000
D31.6 Orbit, unspecified	0.002	0.998	0.000
D31.5 Lachrymal gland and duct	0.002	0.998	0.000
D31.4 Ciliary body	0.002	0.998	0.000
D31.3 Choroid	0.002	0.998	0.000
D31.2 Retina	0.002	0.998	0.000
D31.1 Cornea	0.002	0.998	0.000
D31.0 Conjunctiva	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.002	0.998	0.000
D32.1 Spinal meninges	0.002	0.998	0.000
D32.0 Cerebral meninges	0.002	0.998	0.000
M79.8 Other specified soft tissue disorders	0.002	0.998	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.002	0.998	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
D36.9 Benign neoplasm of unspecified site	0.002	0.998	0.000
D36.7 Other specified sites	0.002	0.998	0.000
D36.0 Lymph nodes	0.002	0.998	0.000
D48.6 Breast	0.002	0.998	0.000
C77.8 Lymph nodes of multiple regions	0.002	0.998	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.002	0.998	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.002	0.998	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.002	0.998	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.002	0.998	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.002	0.998	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.002	0.998	0.000
D11.9 Major salivary gland, unspecified	0.002	0.998	0.000
D11.7 Other major salivary glands	0.002	0.998	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.002	0.998	0.000
D22 Melanocytic naevi	0.002	0.998	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.002	0.998	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.002	0.998	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.002	0.998	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.002	0.998	0.000
C76.7 Other ill-defined sites	0.002	0.998	0.000
C76.5 Lower limb	0.002	0.998	0.000
C76.4 Upper limb	0.002	0.998	0.000
C76.3 Pelvis	0.002	0.998	0.000
C76.2 Abdomen	0.002	0.998	0.000
C76.1 Thorax	0.002	0.998	0.000
C76.0 Head, face and neck	0.002	0.998	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.6 Other serum reactions	0.002	0.998	0.000
T80.5 Anaphylactic shock due to serum	0.002	0.998	0.000
T80.4 Rh incompatibility reaction	0.002	0.998	0.000
T80.3 ABO incompatibility reaction	0.002	0.998	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.002	0.998	0.000
T86.4 Liver transplant failure and rejection	0.002	0.998	0.000
T86.3 Heart-lung transplant failure and rejection	0.002	0.998	0.000
T86.2 Heart transplant failure and rejection	0.002	0.998	0.000
T86.1 Kidney transplant failure and rejection	0.002	0.998	0.000
T86.0 Bone-marrow transplant rejection	0.002	0.998	0.000
T87.6 Other and unspecified complications of amputation stump	0.002	0.998	0.000
T87.5 Necrosis of amputation stump	0.002	0.998	0.000
T87.4 Infection of amputation stump	0.002	0.998	0.000
T87.3 Neuroma of amputation stump	0.002	0.998	0.000
T87.2 Complications of other reattached body part	0.002	0.998	0.000
T87.1 Complications of reattached (part of) lower extremity	0.002	0.998	0.000
T87.0 Complications of reattached (part of) upper extremity	0.002	0.998	0.000
T88.9 Complication of surgical and medical care, unspecified	0.002	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
T88.5 Other complications of anaesthesia	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.002	0.998	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.002	0.998	0.000
T88.2 Shock due to anaesthesia	0.002	0.998	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.002	0.998	0.000
T88.0 Infection following immunisation	0.002	0.998	0.000
I21 Acute myocardial infarction	0.000	0.998	0.002
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.002	0.998	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.002	0.998	0.000
C79.2 Secondary malignant neoplasm of skin	0.002	0.998	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.002	0.998	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.002	0.998	0.000
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.998	0.002
S92 Fracture of foot, except ankle	0.002	0.998	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.998	0.002
T78.3 Angioneurotic oedema	0.002	0.998	0.000
C77.2 Intra-abdominal lymph nodes	0.002	0.998	0.000
D11.0 Parotid gland	0.001	0.998	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998	0.000
M79.88 Other specified soft tissue disorders (Other)	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.002	0.998	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.002	0.998	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.002	0.998	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.002	0.998	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.002	0.998	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.002	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.002	0.998	0.000
I51.8 Other ill-defined heart diseases	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.002	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
D00-D09 In situ neoplasms	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.001	0.998	0.000
D48.7 Other specified sites	0.001	0.998	0.000
D48.5 Skin	0.001	0.998	0.000
D48.4 Peritoneum	0.001	0.998	0.000
D48.3 Retroperitoneum	0.001	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.001	0.998	0.000
D48.0 Bone and articular cartilage	0.001	0.998	0.000
D03 Melanoma in situ	0.002	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.001	0.998	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.002	0.998	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.001	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.001	0.998	0.000
S92.3 Fracture of metatarsal bone	0.001	0.998	0.000
T78.4 Allergy, unspecified	0.001	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
Chapter II Neoplasms	0.002	0.998	0.000
D22.9 Melanocytic naevi, unspecified	0.001	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.001	0.998	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.001	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.001	0.998	0.000
D22.0 Melanocytic naevi of lip	0.001	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.001	0.998	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.998	0.001
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.001	0.998	0.000
M79.0 Rheumatism, unspecified	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.001	0.998	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.001	0.998	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.001	0.998	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.001	0.998	0.000
T82.3 Mechanical complication of other vascular grafts	0.001	0.998	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.001	0.998	0.000
T82.1 Mechanical complication of cardiac electronic device	0.001	0.998	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.001	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.001	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.001	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.001	0.998	0.000
S97 Crushing injury of ankle and foot	0.001	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.998	0.000
S91 Open wound of ankle and foot	0.001	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
S80-S89 Injuries to the knee and lower leg	0.002	0.998	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.001	0.998	0.000
T78.9 Adverse effect, unspecified	0.001	0.998	0.000
T78.8 Other adverse effects, not elsewhere classified	0.001	0.998	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.001	0.998	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.001	0.998	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.001	0.998	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.998	0.001
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.998	0.001
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.998	0.001
Z95.2 Presence of prosthetic heart valve	0.000	0.998	0.001
D46 Myelodysplastic syndromes	0.001	0.998	0.000
T75 Effects of other external causes	0.001	0.998	0.000
T74 Maltreatment syndromes	0.001	0.998	0.000
T73 Effects of other deprivation	0.001	0.998	0.000
T70 Effects of air pressure and water pressure	0.001	0.998	0.000
T69 Other effects of reduced temperature	0.001	0.998	0.000
T67 Effects of heat and light	0.001	0.998	0.000
T71 Asphyxiation	0.001	0.998	0.000
T68 Hypothermia	0.001	0.998	0.000
T66 Unspecified effects of radiation	0.001	0.998	0.000
T79-T79 Certain early complications of trauma	0.001	0.998	0.000
T33-T35 Frostbite	0.001	0.998	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.001	0.998	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.001	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.001	0.998	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.001	0.998	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.001	0.998	0.000
T00-T07 Injuries involving multiple body regions	0.001	0.998	0.000
S10-S19 Injuries to the neck	0.001	0.998	0.000
K31.8 Other specified diseases of stomach and duodenum	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.001	0.998	0.000
S92.7 Multiple fractures of foot	0.001	0.998	0.000
S92.5 Fracture of other toe	0.001	0.998	0.000
S92.4 Fracture of great toe	0.001	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.001	0.998	0.000
S92.1 Fracture of talus	0.001	0.998	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.001	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.001	0.998	0.000
L30.9 Dermatitis, unspecified	0.001	0.998	0.000
S82.3 Fracture of lower end of tibia	0.001	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.001	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.998	0.000
S90.0 Contusion of ankle	0.001	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.001	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.001	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.001	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.001	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.001	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.001	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations