TreeWAS – Variant ID: rs11755266

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000
Chapter X Diseases of the respiratory system	0.997	0.003
Chapter XX External causes of morbidity and mortality	0.996	0.004
M50-M54 Other dorsopathies	0.995	0.005
J44 Other chronic obstructive pulmonary disease	0.994	0.006
H55-H59 Other disorders of eye and adnexa	0.993	0.007
H30-H36 Disorders of choroid and retina	0.993	0.007
J44.9 Chronic obstructive pulmonary disease, unspecified	0.993	0.007
J40-J47 Chronic lower respiratory diseases	0.992	0.008
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.989	0.011
Chapter IV Endocrine, nutritional and metabolic diseases	0.988	0.012
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.987	0.013
E65-E68 Obesity and other hyperalimentation	0.983	0.017
E66 Obesity	0.981	0.019
E66.9 Obesity, unspecified	0.980	0.020
Chapter VI Diseases of the nervous system	0.977	0.023
M54 Dorsalgia	0.975	0.025
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.965	0.035
J95-J99 Other diseases of the respiratory system	0.965	0.035
M70-M79 Other soft tissue disorders	0.960	0.040
M51 Other intervertebral disk disorders	0.956	0.044
H33 Retinal detachments and breaks	0.952	0.048
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.945	0.055
M79 Other soft tissue disorders, not elsewhere classified	0.945	0.055
G80-G83 Cerebral palsy and other paralytic syndromes	0.944	0.056
Chapter I Certain infectious and parasitic diseases	0.942	0.058
H01 Other inflammation of eyelid	0.940	0.060
Z70-Z76 Persons encountering health services in other circumstances	0.937	0.063
Chapter XXI Factors influencing health status and contact with health services	0.937	0.063
J98 Other respiratory disorders	0.936	0.064
M79.6 Pain in limb	0.933	0.067
H35 Other retinal disorders	0.932	0.068
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.932	0.068
G50-G59 Nerve, nerve root and plexus disorders	0.931	0.069
H55 Nystagmus and other irregular eye movements	0.930	0.070
H01.0 Blepharitis	0.928	0.072
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.927	0.073
M79.66 Pain in limb (Lower leg)	0.927	0.073
M54.2 Cervicalgia	0.927	0.073
H57 Other disorders of eye and adnexa	0.924	0.076
T66-T78 Other and unspecified effects of external causes	0.923	0.077
T78 Adverse effects, not elsewhere classified	0.918	0.082
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.917	0.083
E50-E64 Other nutritional deficiencies	0.914	0.086
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.912	0.088
M05-M14 Inflammatory polyarthropathies	0.909	0.091
B07 Viral warts	0.905	0.095
G57 Mononeuropathies of lower limb	0.904	0.096
M86-M90 Other osteopathies	0.903	0.097
H43-H45 Disorders of vitreous body and globe	0.902	0.098
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.899	0.101
X40-X49 Accidental poisoning by and exposure to noxious substances	0.899	0.101
M51.2 Other specified intervertebral disk displacement	0.898	0.102
M54.3 Sciatica	0.895	0.105
G57.8 Other mononeuropathies of lower limb	0.892	0.108
M54.22 Cervicalgia (Cervical region)	0.892	0.108
T15-T19 Effects of foreign body entering through natural orifice	0.888	0.112
Q80-Q89 Other congenital malformations	0.885	0.115
H33.3 Retinal breaks without detachment	0.885	0.115
H35.8 Other specified retinal disorders	0.878	0.122
G82 Paraplegia and tetraplegia	0.876	0.124
Z74 Problems related to care-provider dependency	0.873	0.127
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.871	0.129
Y51 Drugs primarily affecting the autonomic nervous system	0.871	0.129
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.870	0.130
M54.9 Dorsalgia, unspecified	0.868	0.132
Q00-Q07 Congenital malformations of the nervous system	0.866	0.134
T17 Foreign body in respiratory tract	0.862	0.138
A30-A49 Other bacterial diseases	0.862	0.138
M06 Other rheumatoid arthritis	0.861	0.139
S10-S19 Injuries to the neck	0.860	0.140
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.860	0.140
E53 Deficiency of other B group vitamins	0.857	0.143
B02 Zoster [herpes zoster]	0.856	0.144
Y48 Anaesthetics and therapeutic gases	0.851	0.148
J98.4 Other disorders of lung	0.850	0.150
Y00-Y09 Assault	0.850	0.150
H33.5 Other retinal detachments	0.849	0.151
T78.3 Angioneurotic oedema	0.848	0.152
G83 Other paralytic syndromes	0.847	0.153
G00-G09 Inflammatory diseases of the central nervous system	0.846	0.154
H33.4 Traction detachment of retina	0.842	0.158
Q60-Q64 Congenital malformations of the urinary system	0.840	0.160
Z95.5 Presence of coronary angioplasty implant and graft	0.839	0.161
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.839	0.161
H57.1 Ocular pain	0.838	0.162
Z95 Presence of cardiac and vascular implants and grafts	0.837	0.163
Z71.2 Person consulting for explanation of investigation findings	0.836	0.164
Z95.1 Presence of aortocoronary bypass graft	0.835	0.165
J20-J22 Other acute lower respiratory infections	0.834	0.166
Z71.3 Dietary counselling and surveillance	0.834	0.166
M51.9 Intervertebral disk disorder, unspecified	0.834	0.166
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.833	0.167
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.832	0.168
T78.0 Anaphylactic shock due to adverse food reaction	0.832	0.168
Y42.5 Other oestrogens and progestogens	0.831	0.169
M45-M49 Spondylopathies	0.830	0.170
Y46 Antiepileptics and anti-Parkinsonism drugs	0.828	0.172
H40-H42 Glaucoma	0.826	0.174
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.826	0.174
H35.2 Other proliferative retinopathy	0.825	0.175
J98.6 Disorders of diaphragm	0.824	0.176
Z95.4 Presence of other heart-valve replacement	0.824	0.176
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.823	0.177
M79.65 Pain in limb (Pelvic region and thigh)	0.819	0.181
Z73 Problems related to life-management difficulty	0.817	0.183
T17.2 Foreign body in pharynx	0.815	0.185
M48 Other spondylopathies	0.814	0.186
H10-H13 Disorders of conjunctiva	0.812	0.188
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.810	0.190
J99 Respiratory disorders in diseases classified elsewhere	0.809	0.191
M54.37 Sciatica (Lumbosacral region)	0.809	0.191
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.809	0.191
Z75 Problems related to medical facilities and other health care	0.804	0.196
E53.8 Deficiency of other specified B group vitamins	0.802	0.198
T78.4 Allergy, unspecified	0.802	0.198
E20-E35 Disorders of other endocrine glands	0.801	0.199
H44 Disorders of globe	0.799	0.201
X58-X59 Accidental exposure to other and unspecified factors	0.798	0.202
M40-M43 Deforming dorsopathies	0.793	0.207
M48.0 Spinal stenosis	0.793	0.207
G83.4 Cauda equina syndrome	0.791	0.209
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.791	0.209
H31 Other disorders of choroid	0.790	0.210
Y43 Primarily systemic agents	0.789	0.211
A49 Bacterial infection of unspecified site	0.789	0.211
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.788	0.212
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.788	0.212
W50-W64 Exposure to animate mechanical forces	0.787	0.213
M48.06 Spinal stenosis (Lumbar region)	0.786	0.214
X50-X57 Overexertion, travel and privation	0.784	0.216
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.783	0.217
M79.1 Myalgia	0.783	0.217
H01.1 Non-infectious dermatoses of eyelid	0.782	0.217
M91-M94 Chondropathies	0.781	0.218
M54.4 Lumbago with sciatica	0.781	0.219
M06.9 Rheumatoid arthritis, unspecified	0.781	0.219
W00-W19 Falls	0.781	0.219
H30 Chorioretinal inflammation	0.780	0.220
J98.0 Diseases of bronchus, not elsewhere classified	0.778	0.222
Z72 Problems related to lifestyle	0.777	0.223
M89 Other disorders of bone	0.776	0.224
T78.2 Anaphylactic shock, unspecified	0.775	0.225
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.774	0.226
H57.9 Disorder of eye and adnexa, unspecified	0.772	0.228
Y42.2 Antithyroid drugs	0.772	0.228
H57.8 Other specified disorders of eye and adnexa	0.772	0.228
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.771	0.229
M79.61 Pain in limb (Shoulder region)	0.770	0.230
Y52 Agents primarily affecting the cardiovascular system	0.768	0.232
Chapter XXII Codes for special purposes	0.766	0.233
Z74.2 Need for assistance at home and no other household member able to render care	0.766	0.234
M77 Other enthesopathies	0.766	0.234
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.764	0.236
S50-S59 Injuries to the elbow and forearm	0.764	0.236
Y42.7 Androgens and anabolic congeners	0.763	0.237
H35.6 Retinal haemorrhage	0.763	0.237
M70 Soft tissue disorders related to use, overuse and pressure	0.763	0.237
H01.9 Inflammation of eyelid, unspecified	0.763	0.237
Q20-Q28 Congenital malformations of the circulatory system	0.762	0.238
M76 Enthesopathies of lower limb, excluding foot	0.762	0.238
M79.5 Residual foreign body in soft tissue	0.762	0.238
M79.2 Neuralgia and neuritis, unspecified	0.761	0.238
H35.4 Peripheral retinal degeneration	0.761	0.239
B02.3 Zoster ocular disease	0.760	0.240
H34 Retinal vascular occlusions	0.759	0.241
J98.8 Other specified respiratory disorders	0.758	0.242
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.758	0.242
E61 Deficiency of other nutrient elements	0.757	0.243
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.756	0.244
M65-M68 Disorders of synovium and tendon	0.756	0.244
H16 Keratitis	0.755	0.245
B99-B99 Other infectious diseases	0.754	0.245
M54.99 Dorsalgia, unspecified (Site unspecified)	0.754	0.246
S30 Superficial injury of abdomen, lower back and pelvis	0.753	0.247
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.752	0.248
M54.36 Sciatica (Lumbar region)	0.752	0.248
T75 Effects of other external causes	0.751	0.249
Z64 Problems related to certain psychosocial circumstances	0.751	0.249
Z59 Problems related to housing and economic circumstances	0.750	0.249
J60-J70 Lung diseases due to external agents	0.750	0.250
Z74.0 Reduced mobility	0.749	0.251
V01-V09 Pedestrian injured in transport accident	0.749	0.251
Q05 Spina bifida	0.749	0.251
M95.0 Acquired deformity of nose	0.749	0.251
G50 Disorders of trigeminal nerve	0.748	0.252
X60-X84 Intentional self-harm	0.747	0.253
A46 Erysipelas	0.747	0.253
Q18 Other congenital malformations of face and neck	0.745	0.255
Y57 Other and unspecified drugs and medicaments	0.743	0.257
H44.2 Degenerative myopia	0.742	0.258
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.741	0.259
M53 Other dorsopathies, not elsewhere classified	0.740	0.260
Y85 Sequelae of transport accidents	0.740	0.260
G82.2 Paraplegia, unspecified	0.739	0.261
G09 Sequelae of inflammatory diseases of central nervous system	0.739	0.261
Q50-Q56 Congenital malformations of genital organs	0.739	0.261
J09-J18 Influenza and pneumonia	0.735	0.265
H03 Disorders of eyelid in diseases classified elsewhere	0.733	0.267
B90-B94 Sequelae of infectious and parasitic diseases	0.732	0.268
E66.8 Other obesity	0.732	0.268
G54 Nerve root and plexus disorders	0.732	0.268
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.731	0.269
H58.8 Visual disturbances in diseases classified elsewhere	0.728	0.272
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.728	0.272
H43 Disorders of vitreous body	0.727	0.273
T00-T07 Injuries involving multiple body regions	0.726	0.274
X20-X29 Contact with venomous animals and plants	0.725	0.275
Q61 Cystic kidney disease	0.725	0.275
A49.9 Bacterial infection, unspecified	0.725	0.275
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.724	0.276
G11 Hereditary ataxia	0.724	0.276
G82.4 Spastic tetraplegia	0.723	0.277
M06.3 Rheumatoid nodule	0.722	0.278
E28 Ovarian dysfunction	0.721	0.279
G57.5 Tarsal tunnel syndrome	0.720	0.280
H33.0 Retinal detachment with retinal break	0.720	0.280
M79.69 Pain in limb (Site unspecified)	0.720	0.280
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.720	0.280
Y40 Systemic antibiotics	0.719	0.281
X10-X19 Contact with heat and hot substances	0.719	0.281
Q85 Phakomatoses, not elsewhere classified	0.718	0.281
H01.8 Other specified inflammation of eyelid	0.718	0.282
Y47 Sedatives, hypnotics and antianxiety drugs	0.718	0.282
J22 Unspecified acute lower respiratory infection	0.717	0.283
A15-A19 Tuberculosis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
M54.46 Lumbago with sciatica (Lumbar region)	0.716	0.284
G80 Infantile cerebral palsy	0.716	0.284
T70 Effects of air pressure and water pressure	0.716	0.284
M05 Seropositive rheumatoid arthritis	0.716	0.284
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.716	0.284
J43 Emphysema	0.715	0.285
G35-G37 Demyelinating diseases of the central nervous system	0.715	0.285
Y53 Agents primarily affecting the gastro-intestinal system	0.714	0.285
S14 Injury of nerves and spinal cord at neck level	0.714	0.286
Z58 Problems related to physical environment	0.714	0.286
Y35-Y36 Legal intervention and operations of war	0.714	0.286
Y10-Y34 Event of undetermined intent	0.714	0.286
X85-X99 Assault	0.714	0.286
X30-X39 Exposure to forces of nature	0.714	0.286
X00-X09 Exposure to smoke, fire and flames	0.714	0.286
W75-W84 Other accidental threats to breathing	0.714	0.286
W65-W74 Accidental drowning and submersion	0.714	0.286
V98-V99 Other and unspecified transport accidents	0.714	0.286
V95-V97 Air and space transport accidents	0.714	0.286
V90-V94 Water transport accidents	0.714	0.286
V70-V79 Bus occupant injured in transport accident	0.714	0.286
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.714	0.286
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.714	0.286
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.714	0.286
Y04 Assault by bodily force	0.713	0.287
Z75.3 Unavailability and inaccessibility of health-care facilities	0.712	0.288
H32 Chorioretinal disorders in diseases classified elsewhere	0.712	0.288
J41 Simple and mucopurulent chronic bronchitis	0.711	0.288
Y48.2 Other and unspecified general anaesthetics	0.711	0.289
G59 Mononeuropathy in diseases classified elsewhere	0.711	0.289
M60-M63 Disorders of muscles	0.711	0.289
G57.3 Lesion of lateral popliteal nerve	0.711	0.289
M07 Psoriatic and enteropathic arthropathies	0.710	0.290
T17.8 Foreign body in other and multiple parts of respiratory tract	0.710	0.290
Q35-Q37 Cleft lip and cleft palate	0.709	0.291
Q30-Q34 Congenital malformations of the respiratory system	0.709	0.291
Z71.1 Person with feared complaint in whom no diagnosis is made	0.708	0.292
Y59 Other and unspecified vaccines and biological substances	0.707	0.293
Y58 Bacterial vaccines	0.707	0.293
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.707	0.293
Y50 Central nervous system stimulants, not elsewhere classified	0.707	0.293
J99.8 Respiratory disorders in other diseases classified elsewhere	0.707	0.293
H17 Corneal scars and opacities	0.707	0.293
B02.9 Zoster without complication	0.706	0.294
H15 Disorders of sclera	0.705	0.295
E67 Other hyperalimentation	0.705	0.295
E68 Sequelae of hyperalimentation	0.705	0.295
J98.2 Interstitial emphysema	0.705	0.295
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.704	0.296
M00-M03 Infectious arthropathies	0.703	0.297
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.703	0.297
M79.60 Pain in limb (Multiple sites)	0.703	0.297
E66.1 Drug-induced obesity	0.703	0.297
M79.9 Soft tissue disorder, unspecified	0.702	0.298
X47 Accidental poisoning by and exposure to other gases and vapours	0.702	0.298
T78.8 Other adverse effects, not elsewhere classified	0.702	0.298
Z73.9 Problem related to life-management difficulty, unspecified	0.702	0.298
Q12 Congenital lens malformations	0.701	0.298
G06 Intracranial and intraspinal abscess and granuloma	0.701	0.299
H40 Glaucoma	0.701	0.299
X49.9 Unspecified place	0.701	0.299
T92 Sequelae of injuries of upper limb	0.700	0.300
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.700	0.300
V80-V89 Other land transport accidents	0.700	0.300
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.700	0.300
M54.0 Panniculitis affecting regions of neck and back	0.699	0.301
Z63 Other problems related to primary support group, including family circumstances	0.699	0.301
G82.5 Tetraplegia, unspecified	0.699	0.301
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.695	0.305
Z72.0 Tobacco use	0.695	0.305
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.694	0.306
H40.2 Primary angle-closure glaucoma	0.693	0.307
Q89 Other congenital malformations, not elsewhere classified	0.693	0.307
W03 Other fall on same level due to collision with, or pushing by, another person	0.693	0.307
M06.0 Seronegative rheumatoid arthritis	0.693	0.307
S19 Other and unspecified injuries of neck	0.692	0.308
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.692	0.308
J96 Respiratory failure, not elsewhere classified	0.692	0.308
M86 Osteomyelitis	0.691	0.309
M54.8 Other dorsalgia	0.690	0.310
B25-B34 Other viral diseases	0.690	0.310
J15 Bacterial pneumonia, not elsewhere classified	0.689	0.311
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.689	0.311
X58 Exposure to other specified factors	0.689	0.311
M73 Soft tissue disorders in diseases classified elsewhere	0.688	0.312
T17.9 Foreign body in respiratory tract, part unspecified	0.688	0.312
T91 Sequelae of injuries of neck and trunk	0.688	0.312
Y48.3 Local anaesthetics	0.688	0.312
J44.8 Other specified chronic obstructive pulmonary disease	0.687	0.313
J80-J84 Other respiratory diseases principally affecting the interstitium	0.687	0.313
M54.23 Cervicalgia (Cervicothoracic region)	0.686	0.314
M99 Biomechanical lesions, not elsewhere classified	0.686	0.314
G53 Cranial nerve disorders in diseases classified elsewhere	0.686	0.314
M51.3 Other specified intervertebral disk degeneration	0.686	0.314
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.686	0.314
M51.4 Schmorl's nodes	0.686	0.314
M48.5 Collapsed vertebra, not elsewhere classified	0.686	0.314
M79.0 Rheumatism, unspecified	0.684	0.316
W20-W49 Exposure to inanimate mechanical forces	0.684	0.316
M90 Osteopathies in diseases classified elsewhere	0.684	0.316
M88 Paget's disease of bone [osteitis deformans]	0.684	0.316
X45 Accidental poisoning by and exposure to alcohol	0.683	0.317
H35.7 Separation of retinal layers	0.683	0.317
M79.68 Pain in limb (Other)	0.682	0.318
Q07 Other congenital malformations of nervous system	0.681	0.319
T78.1 Other adverse food reactions, not elsewhere classified	0.680	0.320
E65 Localised adiposity	0.680	0.320
Y49 Psychotropic drugs, not elsewhere classified	0.680	0.320
Y52.3 Coronary vasodilators, not elsewhere classified	0.679	0.321
G57.9 Mononeuropathy of lower limb, unspecified	0.679	0.321
J67 Hypersensitivity pneumonitis due to organic dust	0.678	0.322
M87 Osteonecrosis	0.678	0.322
Q63 Other congenital malformations of kidney	0.678	0.322
S56 Injury of muscle and tendon at forearm level	0.678	0.322
M79.3 Panniculitis, unspecified	0.678	0.322
Q82 Other congenital malformations of skin	0.678	0.322
W06 Fall involving bed	0.677	0.323
G82.1 Spastic paraplegia	0.676	0.324
B85-B89 Pediculosis, acariasis and other infestations	0.675	0.325
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.675	0.325
A75-A79 Rickettsioses	0.675	0.325
A70-A74 Other diseases caused by chlamydiae	0.675	0.325
A65-A69 Other spirochaetal diseases	0.675	0.325
A20-A28 Certain zoonotic bacterial diseases	0.675	0.325
T18 Foreign body in alimentary tract	0.675	0.325
M54.94 Dorsalgia, unspecified (Thoracic region)	0.675	0.325
A49.8 Other bacterial infections of unspecified site	0.675	0.325
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.675	0.325
J98.1 Pulmonary collapse	0.674	0.326
E53.9 Vitamin B deficiency, unspecified	0.674	0.326
S12 Fracture of neck	0.673	0.327
Z64.0 Problems related to unwanted pregnancy	0.673	0.327
Y85.0 Sequelae of motor-vehicle accident	0.672	0.328
Z29 Need for other prophylactic measures	0.672	0.328
S51 Open wound of forearm	0.672	0.328
Z70 Counselling related to sexual attitude, behaviour and orientation	0.671	0.328
J98.5 Diseases of mediastinum, not elsewhere classified	0.671	0.329
J98.3 Compensatory emphysema	0.671	0.329
Y41 Other systemic anti-infectives and antiparasitics	0.671	0.329
H10 Conjunctivitis	0.670	0.330
Y46.6 Other and unspecified antiepileptics	0.669	0.331
Y86 Sequelae of other accidents	0.669	0.331
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.669	0.331
H35.1 Retinopathy of prematurity	0.668	0.331
S30.0 Contusion of lower back and pelvis	0.668	0.332
B06 Rubella [German measles]	0.668	0.332
B05 Measles	0.668	0.332
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.668	0.332
B04 Monkeypox	0.668	0.332
B03 Smallpox	0.668	0.332
G52 Disorders of other cranial nerves	0.667	0.333
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.666	0.334
M20-M25 Other joint disorders	0.666	0.334
Y00 Assault by blunt object	0.665	0.334
M72 Fibroblastic disorders	0.665	0.335
T33-T35 Frostbite	0.665	0.335
T26-T28 Burns and corrosions confined to eye and internal organs	0.665	0.335
M54.28 Cervicalgia-Sacral/sacrococ	0.665	0.335
M54.27 Cervicalgia-Lumbosacral	0.665	0.335
M54.26 Cervicalgia-Lumbar	0.665	0.335
M54.25 Cervicalgia-Thoracolumbar	0.665	0.335
M54.24 Cervicalgia-Thoracic	0.665	0.335
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.665	0.335
M54.20 Cervicalgia-Mult site	0.665	0.335
M43 Other deforming dorsopathies	0.663	0.337
T74 Maltreatment syndromes	0.662	0.338
T73 Effects of other deprivation	0.662	0.338
T69 Other effects of reduced temperature	0.662	0.338
T67 Effects of heat and light	0.662	0.338
T71 Asphyxiation	0.662	0.338
T66 Unspecified effects of radiation	0.662	0.338
B50-B64 Protozoal diseases	0.661	0.339
S90-S99 Injuries to the ankle and foot	0.660	0.339
A50-A64 Infections with a predominantly sexual mode of transmission	0.660	0.340
A40 Streptococcal septicaemia	0.660	0.340
Z76 Persons encountering health services in other circumstances	0.660	0.340
H20 Iridocyclitis	0.659	0.341
T78.9 Adverse effect, unspecified	0.658	0.342
Q38-Q45 Other congenital malformations of the digestive system	0.658	0.342
E29 Testicular dysfunction	0.658	0.342
Y42.9 Other and unspecified hormone antagonists	0.658	0.342
Y42.4 Oral contraceptives	0.658	0.342
Y42.1 Thyroid hormones and substitutes	0.658	0.342
T68 Hypothermia	0.657	0.342
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.657	0.343
Y60-Y69 Misadventures to patients during surgical and medical care	0.657	0.343
G60 Hereditary and idiopathic neuropathy	0.657	0.343
X50 Overexertion and strenuous or repetitive movements	0.656	0.344
Y46.4 Iminostilbenes	0.655	0.344
E64 Sequelae of malnutrition and other nutritional deficiencies	0.655	0.345
E63 Other nutritional deficiencies	0.655	0.345
E56 Other vitamin deficiencies	0.655	0.345
E51 Thiamine deficiency	0.655	0.345
E50 Vitamin A deficiency	0.655	0.345
E60 Dietary zinc deficiency	0.655	0.345
E59 Dietary selenium deficiency	0.655	0.345
E58 Dietary calcium deficiency	0.655	0.345
E54 Ascorbic acid deficiency	0.655	0.345
E52 Niacin deficiency [pellagra]	0.655	0.345
E66.0 Obesity due to excess calories	0.655	0.345
Y43.0 Antiallergic and antiemetic drugs	0.654	0.346
V40-V49 Car occupant injured in transport accident	0.653	0.347
S11 Open wound of neck	0.653	0.347
B00 Herpesviral [herpes simplex] infections	0.652	0.348
M12 Other specific arthropathies	0.652	0.348
M09 Juvenile arthritis in diseases classified elsewhere	0.652	0.348
M08 Juvenile arthritis	0.652	0.348
H33.1 Retinoschisis and retinal cysts	0.652	0.348
Z72.2 Drug use	0.651	0.349
G83.9 Paralytic syndrome, unspecified	0.650	0.350
M54.29 Cervicalgia-Site unspe	0.649	0.351
V20-V29 Motorcycle rider injured in transport accident	0.649	0.351
G57.4 Lesion of medial popliteal nerve	0.648	0.352
G57.2 Lesion of femoral nerve	0.648	0.352
G57.0 Lesion of sciatic nerve	0.648	0.352
Z74.1 Need for assistance with personal care	0.647	0.353
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.646	0.353
T17.5 Foreign body in bronchus	0.646	0.354
Q83 Congenital malformations of breast	0.645	0.355
E61.1 Iron deficiency	0.645	0.355
Z71.7 Human immunodeficiency virus [HIV] counselling	0.645	0.355
Z71.5 Drug abuse counselling and surveillance	0.645	0.355
Z71.4 Alcohol abuse counselling and surveillance	0.645	0.355
Z71.0 Person consulting on behalf of another person	0.645	0.355
B35-B49 Mycoses	0.645	0.355
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.645	0.355
M40 Kyphosis and lordosis	0.645	0.355
X48 Accidental poisoning by and exposure to pesticides	0.644	0.355
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.644	0.355
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.644	0.355
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system	0.644	0.355
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.644	0.355
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.644	0.355
Q61.0 Congenital single renal cyst	0.643	0.357
G55.0 Nerve root and plexus compressions in neoplastic disease	0.642	0.358
M54.35 Sciatica (Thoracolumbar region)	0.642	0.358
M54.34 Sciatica-Thoracic	0.642	0.358
M54.33 Sciatica-Cervicothoracic	0.642	0.358
M54.32 Sciatica-Cervical	0.642	0.358
M54.31 Sciatica-Occipit-atl-axl	0.642	0.358
M54.30 Sciatica (Multiple sites in spine)	0.642	0.358
G81 Hemiplegia	0.642	0.358
Q05.4 Unspecified spina bifida with hydrocephalus	0.641	0.359
Z73.8 Other problems related to life-management difficulty	0.641	0.359
V10-V19 Pedal cyclist injured in transport accident	0.640	0.360
A80-A89 Viral infections of the central nervous system	0.640	0.360
G11.4 Hereditary spastic paraplegia	0.640	0.360
Z74.8 Other problems related to care-provider dependency	0.640	0.360
M80-M85 Disorders of bone density and structure	0.640	0.360
M54.6 Pain in thoracic spine	0.640	0.360
Q21 Congenital malformations of cardiac septa	0.639	0.361
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.639	0.361
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.639	0.361
M35 Other systemic involvement of connective tissue	0.639	0.361
M54.1 Radiculopathy	0.639	0.361
M95.4 Acquired deformity of chest and rib	0.639	0.361
Z75.5 Holiday relief care	0.637	0.363
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.637	0.363
T19 Foreign body in genito-urinary tract	0.637	0.363
T15 Foreign body on external eye	0.637	0.363
Z59.8 Other problems relating to housing and economic circumstances	0.637	0.363
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.636	0.364
M79.7 Fibromyalgia	0.636	0.364
M79.15 Myalgia (Pelvic region and thigh)	0.635	0.365
B02.2 Zoster with other nervous system involvement	0.635	0.365
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.634	0.365
Q84 Other congenital malformations of integument	0.634	0.365
Q81 Epidermolysis bullosa	0.634	0.365
Q80 Congenital ichthyosis	0.634	0.365
Y54.3 Benzothiadiazine derivatives	0.634	0.366

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations