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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117593613
log Bayes Factor = 20.9111
Chromosome 14   position 88,296,569  (GRCh37) Explore rs117593613 on Ensembl!
Variant rs117593613 is part of Cluster X0047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
M16 Coxarthrosis [arthrosis of hip]
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
M16.9 Coxarthrosis, unspecified
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
Chapter XI Diseases of the digestive system
0.987 0.013 0.000
Chapter I Certain infectious and parasitic diseases
0.985 0.015 0.000
M20-M25 Other joint disorders
0.984 0.016 0.000
N20-N23 Urolithiasis
0.983 0.017 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.981 0.019 0.000
M06 Other rheumatoid arthritis
0.975 0.025 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.972 0.028 0.000
I20-I25 Ischaemic heart diseases
0.964 0.036 0.000
N23 Unspecified renal colic
0.963 0.037 0.000
K50-K52 Noninfective enteritis and colitis
0.960 0.040 0.000
M06.9 Rheumatoid arthritis, unspecified
0.960 0.040 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.958 0.042 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.957 0.043 0.000
M17 Gonarthrosis [arthrosis of knee]
0.956 0.044 0.000
F30-F39 Mood [affective] disorders
0.951 0.049 0.000
I10-I15 Hypertensive diseases
0.951 0.049 0.000
M25 Other joint disorders, not elsewhere classified
0.951 0.049 0.000
Z72 Problems related to lifestyle
0.950 0.050 0.000
N25-N29 Other disorders of kidney and ureter
0.949 0.051 0.000
K50 Crohn's disease [regional enteritis]
0.948 0.052 0.000
Z72.0 Tobacco use
0.945 0.055 0.000
S80-S89 Injuries to the knee and lower leg
0.943 0.057 0.000
T39.1 4-Aminophenol derivatives
0.932 0.068 0.000
I25 Chronic ischaemic heart disease
0.930 0.070 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.923 0.077 0.000
A00-A09 Intestinal infectious diseases
0.920 0.080 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.920 0.080 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.916 0.084 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.915 0.085 0.000
M50-M54 Other dorsopathies
0.914 0.086 0.000
K50.9 Crohn's disease, unspecified
0.912 0.088 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.909 0.091 0.000
N10-N16 Renal tubulo-interstitial diseases
0.909 0.091 0.000
I10 Essential (primary) hypertension
0.909 0.091 0.000
F31 Bipolar affective disorder
0.907 0.093 0.000
I25.2 Old myocardial infarction
0.903 0.097 0.000
M17.9 Gonarthrosis, unspecified
0.902 0.098 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.901 0.099 0.000
S00-S09 Injuries to the head
0.900 0.100 0.000
S82 Fracture of lower leg, including ankle
0.899 0.101 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.899 0.101 0.000
K70-K77 Diseases of liver
0.897 0.103 0.000
M54 Dorsalgia
0.891 0.109 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.890 0.110 0.000
D60-D64 Aplastic and other anaemias
0.888 0.112 0.000
A04 Other bacterial intestinal infections
0.885 0.115 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.882 0.118 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.876 0.123 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.876 0.124 0.000
K90-K93 Other diseases of the digestive system
0.873 0.127 0.000
M40-M43 Deforming dorsopathies
0.871 0.128 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.871 0.129 0.000
M25.5 Pain in joint
0.871 0.129 0.000
M13 Other arthritis
0.870 0.130 0.000
M25.7 Osteophyte
0.868 0.132 0.000
Z96.6 Presence of orthopaedic joint implants
0.866 0.134 0.000
M54.5 Low back pain
0.866 0.134 0.000
K65-K67 Diseases of peritoneum
0.866 0.134 0.000
M16.1 Other primary coxarthrosis
0.864 0.136 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.862 0.138 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.861 0.139 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.859 0.141 0.000
Z96 Presence of other functional implants
0.858 0.142 0.000
B95-B98 Bacterial, viral and other infectious agents
0.854 0.146 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.854 0.146 0.000
M10 Gout
0.852 0.148 0.000
N20 Calculus of kidney and ureter
0.851 0.149 0.000
A04.8 Other specified bacterial intestinal infections
0.851 0.149 0.000
M24 Other specific joint derangements
0.846 0.154 0.000
T39.0 Salicylates
0.845 0.155 0.000
S82.8 Fractures of other parts of lower leg
0.844 0.156 0.000
B07 Viral warts
0.841 0.159 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.841 0.159 0.000
T42.4 Benzodiazepines
0.838 0.162 0.000
D64 Other anaemias
0.836 0.164 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.836 0.164 0.000
S20-S29 Injuries to the thorax
0.833 0.166 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.831 0.168 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.831 0.169 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.829 0.171 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.826 0.174 0.000
Chapter X Diseases of the respiratory system
0.825 0.175 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.825 0.175 0.000
K92 Other diseases of digestive system
0.820 0.180 0.000
S01 Open wound of head
0.819 0.181 0.000
M70-M79 Other soft tissue disorders
0.818 0.182 0.000
F10.0 Acute intoxication
0.816 0.184 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.815 0.185 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.813 0.187 0.000
I95 Hypotension
0.813 0.187 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.808 0.192 0.000
D80-D89 Certain disorders involving the immune mechanism
0.807 0.193 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.806 0.193 0.000
I22 Subsequent myocardial infarction
0.806 0.194 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.805 0.195 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.801 0.199 0.000
M54.59 Low back pain (Site unspecified)
0.800 0.200 0.000
D64.9 Anaemia, unspecified
0.799 0.201 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.798 0.202 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.797 0.203 0.000
M54.9 Dorsalgia, unspecified
0.797 0.203 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.796 0.204 0.000
Z30 Contraceptive management
0.796 0.204 0.000
M16.0 Primary coxarthrosis, bilateral
0.795 0.205 0.000
M20 Acquired deformities of fingers and toes
0.794 0.206 0.000
F60-F69 Disorders of adult personality and behaviour
0.793 0.207 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.790 0.210 0.000
K50.0 Crohn's disease of small intestine
0.788 0.212 0.000
Chapter XX External causes of morbidity and mortality
0.788 0.212 0.000
F10.1 Harmful use
0.787 0.213 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.787 0.213 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.782 0.218 0.000
N13 Obstructive and reflux uropathy
0.781 0.219 0.000
M17.1 Other primary gonarthrosis
0.780 0.220 0.000
K66 Other disorders of peritoneum
0.780 0.220 0.000
M13.9 Arthritis, unspecified
0.779 0.221 0.000
K50.1 Crohn's disease of large intestine
0.779 0.221 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.779 0.221 0.000
N17-N19 Renal failure
0.777 0.223 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.777 0.223 0.000
M07 Psoriatic and enteropathic arthropathies
0.777 0.223 0.000
D50-D53 Nutritional anaemias
0.777 0.223 0.000
M25.77 Osteophyte (Ankle and foot)
0.775 0.225 0.000
M80-M85 Disorders of bone density and structure
0.774 0.226 0.000
I24 Other acute ischaemic heart diseases
0.774 0.226 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.773 0.227 0.000
S82.1 Fracture of upper end of tibia
0.773 0.227 0.000
K50.8 Other Crohn's disease
0.771 0.229 0.000
M34 Systemic sclerosis
0.770 0.230 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.769 0.231 0.000
M18 Arthrosis of first carpometacarpal joint
0.769 0.231 0.000
R30-R39 Symptoms and signs involving the urinary system
0.767 0.233 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.767 0.233 0.000
Chapter XXII Codes for special purposes
0.767 0.233 0.000
M25.57 Pain in joint (Ankle and foot)
0.766 0.234 0.000
I95.9 Hypotension, unspecified
0.766 0.234 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.765 0.235 0.000
I60-I69 Cerebrovascular diseases
0.760 0.240 0.000
L20-L30 Dermatitis and eczema
0.756 0.244 0.000
M05 Seropositive rheumatoid arthritis
0.755 0.244 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.754 0.246 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.754 0.246 0.000
F99-F99 Unspecified mental disorder
0.751 0.249 0.000
Chapter VIII Diseases of the ear and mastoid process
0.750 0.250 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.749 0.251 0.000
M45-M49 Spondylopathies
0.749 0.251 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.749 0.251 0.000
M10.9 Gout, unspecified
0.749 0.251 0.000
M43 Other deforming dorsopathies
0.748 0.252 0.000
M24.1 Other articular cartilage disorders
0.747 0.253 0.000
R50-R69 General symptoms and signs
0.746 0.254 0.000
N00-N08 Glomerular diseases
0.746 0.254 0.000
O60-O75 Complications of labour and delivery
0.745 0.255 0.000
R31 Unspecified haematuria
0.744 0.256 0.000
F10.2 Dependence syndrome
0.744 0.256 0.000
S60-S69 Injuries to the wrist and hand
0.744 0.256 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.744 0.256 0.000
M22 Disorders of patella
0.743 0.257 0.000
O00-O08 Pregnancy with abortive outcome
0.742 0.258 0.000
K51 Ulcerative colitis
0.741 0.258 0.000
K76 Other diseases of liver
0.740 0.260 0.000
M54.50 Low back pain (Multiple sites in spine)
0.739 0.261 0.000
Z30.2 Sterilisation
0.739 0.261 0.000
M86-M90 Other osteopathies
0.737 0.263 0.000
N30-N39 Other diseases of urinary system
0.737 0.263 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.737 0.263 0.000
I12 Hypertensive renal disease
0.737 0.263 0.000
M25.8 Other specified joint disorders
0.735 0.265 0.000
F31.9 Bipolar affective disorder, unspecified
0.735 0.265 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.734 0.266 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.733 0.267 0.000
N28.8 Other specified disorders of kidney and ureter
0.731 0.269 0.000
F10.3 Withdrawal state
0.730 0.269 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.730 0.270 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.729 0.271 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.729 0.271 0.000
I05-I09 Chronic rheumatic heart diseases
0.728 0.271 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.727 0.273 0.000
N20.1 Calculus of ureter
0.727 0.273 0.000
K75 Other inflammatory liver diseases
0.727 0.273 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.725 0.274 0.000
K55-K64 Other diseases of intestines
0.723 0.277 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.723 0.277 0.000
M79.8 Other specified soft tissue disorders
0.722 0.278 0.000
S81 Open wound of lower leg
0.722 0.278 0.000
F33 Recurrent depressive disorder
0.722 0.278 0.000
T66-T78 Other and unspecified effects of external causes
0.721 0.279 0.000
F03 Unspecified dementia
0.721 0.279 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.720 0.279 0.000
R69 Unknown and unspecified causes of morbidity
0.720 0.280 0.000
K66.0 Peritoneal adhesions
0.718 0.282 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.718 0.282 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M15 Polyarthrosis
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.717 0.283 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
M16.7 Other secondary coxarthrosis
0.716 0.283 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.716 0.283 0.000
M16.5 Other posttraumatic coxarthrosis
0.716 0.283 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.716 0.283 0.000
M16.3 Other dysplastic coxarthrosis
0.716 0.283 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.716 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.715 0.285 0.000
Chapter VII Diseases of the eye and adnexa
0.714 0.286 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M11 Other crystal arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.711 0.289 0.000
M17.0 Primary gonarthrosis, bilateral
0.710 0.290 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.710 0.290 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.709 0.291 0.000
B35-B49 Mycoses
0.706 0.293 0.000
F32 Depressive episode
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
B15-B19 Viral hepatitis
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.705 0.295 0.000
M33 Dermatopolymyositis
0.705 0.295 0.000
M32 Systemic lupus erythematosus
0.705 0.295 0.000
M30 Polyarteritis nodosa and related conditions
0.705 0.295 0.000
M21 Other acquired deformities of limbs
0.705 0.295 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.705 0.295 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.704 0.296 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.704 0.296 0.000
T39.4 Antirheumatics, not elsewhere classified
0.704 0.296 0.000
T39.2 Pyrazolone derivatives
0.704 0.296 0.000
N21 Calculus of lower urinary tract
0.703 0.297 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.702 0.297 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.702 0.298 0.000
M31 Other necrotising vasculopathies
0.701 0.299 0.000
S80 Superficial injury of lower leg
0.701 0.299 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.700 0.299 0.000
M06.8 Other specified rheumatoid arthritis
0.699 0.301 0.000
M06.4 Inflammatory polyarthropathy
0.699 0.301 0.000
M06.3 Rheumatoid nodule
0.699 0.301 0.000
M06.2 Rheumatoid bursitis
0.699 0.301 0.000
M06.1 Adult-onset Still's disease
0.699 0.301 0.000
M06.0 Seronegative rheumatoid arthritis
0.699 0.301 0.000
K70 Alcoholic liver disease
0.698 0.302 0.000
Z36 Antenatal screening
0.697 0.302 0.000
N99-N99 Other disorders of the genitourinary system
0.697 0.303 0.000
A04.5 Campylobacter enteritis
0.697 0.303 0.000
Z76 Persons encountering health services in other circumstances
0.697 0.303 0.000
Z74 Problems related to care-provider dependency
0.697 0.303 0.000
Z73 Problems related to life-management difficulty
0.697 0.303 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.697 0.303 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.696 0.304 0.000
Z71.8 Other specified counselling
0.696 0.304 0.000
S01.1 Open wound of eyelid and periocular area
0.696 0.304 0.000
I77 Other disorders of arteries and arterioles
0.694 0.306 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.693 0.307 0.000
I23 Certain current complications following acute myocardial infarction
0.691 0.309 0.000
S00 Superficial injury of head
0.690 0.310 0.000
M54.57 Low back pain (Lumbosacral region)
0.689 0.311 0.000
B25-B34 Other viral diseases
0.689 0.311 0.000
X60-X84 Intentional self-harm
0.689 0.311 0.000
N28.1 Cyst of kidney, acquired
0.689 0.311 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.688 0.312 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.688 0.312 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.688 0.312 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.688 0.312 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.688 0.312 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.688 0.312 0.000
M41 Scoliosis
0.687 0.313 0.000
Z80 Family history of malignant neoplasm
0.687 0.313 0.000
D55-D59 Haemolytic anaemias
0.687 0.313 0.000
N13.3 Other and unspecified hydronephrosis
0.687 0.313 0.000
D86 Sarcoidosis
0.687 0.313 0.000
M54.56 Low back pain (Lumbar region)
0.686 0.314 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.686 0.314 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.686 0.314 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.686 0.314 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.686 0.314 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.686 0.314 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.686 0.314 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.686 0.314 0.000
F11 Mental and behavioural disorders due to use of opioids
0.686 0.314 0.000
M17.5 Other secondary gonarthrosis
0.685 0.315 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.685 0.315 0.000
M17.3 Other posttraumatic gonarthrosis
0.685 0.315 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.685 0.315 0.000
O36 Maternal care for other known or suspected foetal problems
0.685 0.315 0.000
I67 Other cerebrovascular diseases
0.684 0.316 0.000
S01.4 Open wound of cheek and temporomandibular area
0.684 0.316 0.000
K92.0 Haematemesis
0.684 0.316 0.000
S82.10 Fracture of upper end of tibia (closed)
0.683 0.317 0.000
F38 Other mood [affective] disorders
0.682 0.318 0.000
F34 Persistent mood [affective] disorders
0.682 0.318 0.000
F30 Manic episode
0.682 0.318 0.000
F39 Unspecified mood [affective] disorder
0.682 0.318 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.682 0.318 0.000
I15 Secondary hypertension
0.682 0.318 0.000
I13 Hypertensive heart and renal disease
0.682 0.318 0.000
I11 Hypertensive heart disease
0.682 0.318 0.000
M25.9 Joint disorder, unspecified
0.681 0.318 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.681 0.318 0.000
M25.3 Other instability of joint
0.681 0.318 0.000
M25.2 Flail joint
0.681 0.318 0.000
M25.1 Fistula of joint
0.681 0.318 0.000
M25.0 Haemarthrosis
0.681 0.318 0.000
S82.2 Fracture of shaft of tibia
0.681 0.318 0.000
Z72.9 Problem related to lifestyle, unspecified
0.681 0.319 0.000
Z72.8 Other problems related to lifestyle
0.681 0.319 0.000
Z72.6 Gambling and betting
0.681 0.319 0.000
Z72.5 High-risk sexual behaviour
0.681 0.319 0.000
Z72.4 Inappropriate diet and eating habits
0.681 0.319 0.000
Z72.3 Lack of physical exercise
0.681 0.319 0.000
Z72.2 Drug use
0.681 0.319 0.000
M35 Other systemic involvement of connective tissue
0.681 0.319 0.000
L40-L45 Papulosquamous disorders
0.681 0.319 0.000
K92.1 Melaena
0.681 0.319 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.680 0.319 0.000
N27 Small kidney of unknown cause
0.680 0.319 0.000
N25 Disorders resulting from impaired renal tubular function
0.680 0.319 0.000
N26 Unspecified contracted kidney
0.680 0.319 0.000
F41 Other anxiety disorders
0.680 0.320 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.680 0.320 0.000
N76 Other inflammation of vagina and vulva
0.679 0.321 0.000
T51 Toxic effect of alcohol
0.678 0.322 0.000
K35-K38 Diseases of appendix
0.678 0.322 0.000
M20.2 Hallux rigidus
0.677 0.322 0.000
I21 Acute myocardial infarction
0.677 0.323 0.000
Z75 Problems related to medical facilities and other health care
0.676 0.324 0.000
S89 Other and unspecified injuries of lower leg
0.676 0.324 0.000
S88 Traumatic amputation of lower leg
0.676 0.324 0.000
S87 Crushing injury of lower leg
0.676 0.324 0.000
S86 Injury of muscle and tendon at lower leg level
0.676 0.324 0.000
S85 Injury of blood vessels at lower leg level
0.676 0.324 0.000
S84 Injury of nerves at lower leg level
0.676 0.324 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.676 0.324 0.000
K72 Hepatic failure, not elsewhere classified
0.675 0.325 0.000
R47-R49 Symptoms and signs involving speech and voice
0.675 0.325 0.000
S70-S79 Injuries to the hip and thigh
0.675 0.325 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.674 0.326 0.000
J20-J22 Other acute lower respiratory infections
0.672 0.328 0.000
Z88.2 Personal history of allergy to sulphonamides
0.672 0.328 0.000
K74 Fibrosis and cirrhosis of liver
0.671 0.329 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.670 0.330 0.000
I74 Arterial embolism and thrombosis
0.670 0.330 0.000
Z92 Personal history of medical treatment
0.669 0.331 0.000
N30 Cystitis
0.669 0.331 0.000
T40.2 Other opioids
0.668 0.332 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.667 0.332 0.000
T43.2 Other and unspecified antidepressants
0.667 0.333 0.000
I25.6 Silent myocardial ischaemia
0.667 0.333 0.000
I25.5 Ischaemic cardiomyopathy
0.667 0.333 0.000
I25.4 Coronary artery aneurysm
0.667 0.333 0.000
I25.3 Aneurysm of heart
0.667 0.333 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.667 0.333 0.000
S06 Intracranial injury
0.666 0.334 0.000
N18 Chronic renal failure
0.665 0.335 0.000
K00 Disorders of tooth development and eruption
0.664 0.336 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.663 0.337 0.000
M10.99 Gout, unspecified (Site unspecified)
0.662 0.338 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.661 0.338 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.661 0.338 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.661 0.338 0.000
T42.3 Barbiturates
0.661 0.338 0.000
T42.2 Succinimides and oxazolidinediones
0.661 0.338 0.000
T42.1 Iminostilbenes
0.661 0.338 0.000
T42.0 Hydantoin derivatives
0.661 0.338 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.662 0.338 0.000
Z83 Family history of other specific disorders
0.661 0.338 0.000
O47 False labour
0.661 0.339 0.000
M43.1 Spondylolisthesis
0.660 0.340 0.000
A07 Other protozoal intestinal diseases
0.660 0.340 0.000
A06 Amoebiasis
0.660 0.340 0.000
A05 Other bacterial foodborne intoxications
0.660 0.340 0.000
A03 Shigellosis
0.660 0.340 0.000
A02 Other Salmonella infections
0.660 0.340 0.000
A01 Typhoid and paratyphoid fevers
0.660 0.340 0.000
A00 Cholera
0.660 0.340 0.000
F10.9 Unspecified mental and behavioural disorder
0.660 0.340 0.000
F10.8 Other mental and behavioural disorders
0.660 0.340 0.000
F10.7 Residual and late-onset psychotic disorder
0.660 0.340 0.000
F10.6 Amnesic syndrome
0.660 0.340 0.000
F10.5 Psychotic disorder
0.660 0.340 0.000
F10.4 Withdrawal state with delirium
0.660 0.340 0.000
K08 Other disorders of teeth and supporting structures
0.659 0.340 0.000
M79.6 Pain in limb
0.659 0.341 0.000
A30-A49 Other bacterial diseases
0.657 0.343 0.000
O85-O92 Complications predominantly related to the puerperium
0.657 0.343 0.000
D61 Other aplastic anaemias
0.656 0.344 0.000
N28.0 Ischaemia and infarction of kidney
0.656 0.344 0.000
R42 Dizziness and giddiness
0.656 0.344 0.000
L29 Pruritus
0.656 0.344 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.656 0.344 0.000
M53 Other dorsopathies, not elsewhere classified
0.655 0.344 0.000
I27 Other pulmonary heart diseases
0.655 0.345 0.000
S01.8 Open wound of other parts of head
0.653 0.347 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.652 0.348 0.000
R63 Symptoms and signs concerning food and fluid intake
0.652 0.348 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.652 0.348 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.652 0.348 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.652 0.348 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.652 0.348 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.652 0.348 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.652 0.348 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.652 0.348 0.000
T44.0 Anticholinesterase agents
0.652 0.348 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.652 0.348 0.000
N15 Other renal tubulo-interstitial diseases
0.652 0.348 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.652 0.348 0.000
N11 Chronic tubulo-interstitial nephritis
0.652 0.348 0.000
N10 Acute tubulo-interstitial nephritis
0.652 0.348 0.000
F31.8 Other bipolar affective disorders
0.650 0.350 0.000
F31.7 Bipolar affective disorder, currently in remission
0.650 0.350 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.650 0.350 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.650 0.350 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.650 0.350 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.650 0.350 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.650 0.350 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.649 0.350 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.647 0.353 0.000
F60 Specific personality disorders
0.646 0.354 0.000
N70 Salpingitis and oophoritis
0.646 0.354 0.000
S08 Traumatic amputation of part of head
0.645 0.354 0.000
S07 Crushing injury of head
0.645 0.354 0.000
S05 Injury of eye and orbit
0.645 0.354 0.000
S04 Injury of cranial nerves
0.645 0.354 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.645 0.354 0.000
Z88.5 Personal history of allergy to narcotic agent
0.645 0.355 0.000
S82.9 Fracture of lower leg, part unspecified
0.645 0.355 0.000
S82.7 Multiple fractures of lower leg
0.645 0.355 0.000
S82.5 Fracture of medial malleolus
0.645 0.355 0.000
S82.4 Fracture of fibula alone
0.645 0.355 0.000
S82.0 Fracture of patella
0.645 0.355 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.644 0.355 0.000
B06 Rubella [German measles]
0.644 0.355 0.000
B05 Measles
0.644 0.355 0.000
B01 Varicella [chickenpox]
0.644 0.355 0.000
B00 Herpesviral [herpes simplex] infections
0.644 0.355 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.644 0.355 0.000
B04 Monkeypox
0.644 0.355 0.000
B03 Smallpox
0.644 0.355 0.000
J95-J99 Other diseases of the respiratory system
0.644 0.356 0.000
S50-S59 Injuries to the elbow and forearm
0.644 0.356 0.000
K77 Liver disorders in diseases classified elsewhere
0.643 0.357 0.000
K73 Chronic hepatitis, not elsewhere classified
0.643 0.357 0.000
K71 Toxic liver disease
0.643 0.357 0.000
L81 Other disorders of pigmentation
0.643 0.357 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.643 0.357 0.000
H80-H83 Diseases of inner ear
0.642 0.357 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.642 0.357 0.000
N20.2 Calculus of kidney with calculus of ureter
0.642 0.358 0.000
M25.54 Pain in joint (Hand)
0.642 0.358 0.000
S09 Other and unspecified injuries of head
0.641 0.359 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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