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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117624816
log Bayes Factor = 14.1981
Chromosome 12   position 18,210,143  (GRCh37) Explore rs117624816 on Ensembl!
Variant rs117624816 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
I73 Other peripheral vascular diseases
0.993 0.007 0.000
G40-G47 Episodic and paroxysmal disorders
0.992 0.008 0.000
R30-R39 Symptoms and signs involving the urinary system
0.990 0.010 0.000
G40 Epilepsy
0.988 0.012 0.000
I84 Haemorrhoids
0.987 0.013 0.000
G90-G99 Other disorders of the nervous system
0.987 0.013 0.000
G40.9 Epilepsy, unspecified
0.987 0.013 0.000
I73.9 Peripheral vascular disease, unspecified
0.983 0.017 0.000
E70-E90 Metabolic disorders
0.980 0.020 0.000
M70-M79 Other soft tissue disorders
0.974 0.026 0.000
M45-M49 Spondylopathies
0.972 0.028 0.000
M50-M54 Other dorsopathies
0.972 0.028 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.959 0.041 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.958 0.042 0.000
R31 Unspecified haematuria
0.956 0.044 0.000
M47 Spondylosis
0.952 0.048 0.000
R33 Retention of urine
0.950 0.050 0.000
G93 Other disorders of brain
0.948 0.052 0.000
E65-E68 Obesity and other hyperalimentation
0.948 0.052 0.000
I84.6 Residual haemorrhoidal skin tags
0.942 0.058 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.941 0.059 0.000
Chapter XX External causes of morbidity and mortality
0.939 0.061 0.000
E10-E14 Diabetes mellitus
0.939 0.061 0.000
Chapter I Certain infectious and parasitic diseases
0.934 0.066 0.000
G44 Other headache syndromes
0.933 0.067 0.000
M54 Dorsalgia
0.931 0.069 0.000
I77 Other disorders of arteries and arterioles
0.928 0.072 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.922 0.078 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.920 0.080 0.000
E20-E35 Disorders of other endocrine glands
0.917 0.083 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.916 0.084 0.000
E87.6 Hypokalaemia
0.915 0.085 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.905 0.094 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.905 0.095 0.000
E66 Obesity
0.904 0.096 0.000
M75 Shoulder lesions
0.904 0.096 0.000
I70 Atherosclerosis
0.902 0.098 0.000
I84.8 Unspecified haemorrhoids with other complications
0.902 0.098 0.000
I74 Arterial embolism and thrombosis
0.895 0.105 0.000
M47.8 Other spondylosis
0.893 0.107 0.000
I80 Phlebitis and thrombophlebitis
0.893 0.107 0.000
G93.3 Postviral fatigue syndrome
0.891 0.109 0.000
G44.2 Tension-type headache
0.890 0.110 0.000
M47.9 Spondylosis, unspecified
0.888 0.112 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.886 0.114 0.000
M54.5 Low back pain
0.886 0.114 0.000
M50 Cervical disk disorders
0.882 0.118 0.000
R94 Abnormal results of function studies
0.878 0.122 0.000
E83 Disorders of mineral metabolism
0.873 0.127 0.000
Chapter XIV Diseases of the genitourinary system
0.873 0.127 0.000
E66.8 Other obesity
0.871 0.129 0.000
B35-B49 Mycoses
0.869 0.131 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.867 0.133 0.000
N20-N23 Urolithiasis
0.867 0.133 0.000
E87.7 Fluid overload
0.865 0.135 0.000
N20 Calculus of kidney and ureter
0.864 0.136 0.000
M86-M90 Other osteopathies
0.864 0.136 0.000
M65-M68 Disorders of synovium and tendon
0.863 0.137 0.000
E11 Non-insulin-dependent diabetes mellitus
0.860 0.140 0.000
M40-M43 Deforming dorsopathies
0.859 0.141 0.000
I73.0 Raynaud's syndrome
0.859 0.141 0.000
I72 Other aneurysm
0.855 0.145 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.853 0.147 0.000
M75.0 Adhesive capsulitis of shoulder
0.853 0.147 0.000
I84.2 Internal haemorrhoids without complication
0.853 0.147 0.000
W00-W19 Falls
0.851 0.149 0.000
I81 Portal vein thrombosis
0.851 0.149 0.000
N20.1 Calculus of ureter
0.846 0.154 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.845 0.155 0.000
R47-R49 Symptoms and signs involving speech and voice
0.842 0.158 0.000
G93.4 Encephalopathy, unspecified
0.841 0.159 0.000
S40-S49 Injuries to the shoulder and upper arm
0.840 0.160 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.839 0.161 0.000
I83 Varicose veins of lower extremities
0.839 0.161 0.000
R94.5 Abnormal results of liver function studies
0.835 0.165 0.000
M54.59 Low back pain (Site unspecified)
0.833 0.167 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.833 0.167 0.000
I84.0 Internal thrombosed haemorrhoids
0.831 0.169 0.000
Chapter VII Diseases of the eye and adnexa
0.827 0.173 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.825 0.175 0.000
I84.5 External haemorrhoids without complication
0.824 0.176 0.000
I78 Diseases of capillaries
0.823 0.177 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.822 0.178 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.821 0.179 0.000
M75.3 Calcific tendinitis of shoulder
0.821 0.179 0.000
R32 Unspecified urinary incontinence
0.821 0.179 0.000
E14 Unspecified diabetes mellitus
0.820 0.180 0.000
I77.1 Stricture of artery
0.818 0.182 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.817 0.183 0.000
Chapter XXII Codes for special purposes
0.813 0.187 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.812 0.188 0.000
E27 Other disorders of adrenal gland
0.810 0.190 0.000
G62 Other polyneuropathies
0.810 0.190 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.808 0.192 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.808 0.192 0.000
M79.6 Pain in limb
0.808 0.192 0.000
M54.9 Dorsalgia, unspecified
0.805 0.195 0.000
S20-S29 Injuries to the thorax
0.805 0.195 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.801 0.199 0.000
B37 Candidiasis
0.796 0.204 0.000
G61 Inflammatory polyneuropathy
0.796 0.204 0.000
I85 Oesophageal varices
0.791 0.209 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.789 0.211 0.000
S90-S99 Injuries to the ankle and foot
0.788 0.212 0.000
M47.82 Other spondylosis (Cervical region)
0.787 0.213 0.000
I87 Other disorders of veins
0.786 0.214 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.783 0.217 0.000
E11.5 With peripheral circulatory complications
0.783 0.217 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.783 0.217 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.782 0.218 0.000
N20.0 Calculus of kidney
0.782 0.218 0.000
M47.89 Other spondylosis (Site unspecified)
0.781 0.219 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.778 0.222 0.000
A80-A89 Viral infections of the central nervous system
0.777 0.223 0.000
I84.4 External haemorrhoids with other complications
0.776 0.224 0.000
G95 Other diseases of spinal cord
0.775 0.225 0.000
M47.86 Other spondylosis (Lumbar region)
0.773 0.227 0.000
E11.9 Without complications
0.773 0.227 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.772 0.228 0.000
M65 Synovitis and tenosynovitis
0.771 0.228 0.000
M80-M85 Disorders of bone density and structure
0.771 0.229 0.000
N99-N99 Other disorders of the genitourinary system
0.771 0.229 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.771 0.229 0.000
A00-A09 Intestinal infectious diseases
0.769 0.231 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.769 0.231 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.765 0.235 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.763 0.237 0.000
I84.3 External thrombosed haemorrhoids
0.763 0.237 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.762 0.238 0.000
M91-M94 Chondropathies
0.760 0.240 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.760 0.240 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.758 0.242 0.000
S50-S59 Injuries to the elbow and forearm
0.757 0.243 0.000
M79.0 Rheumatism, unspecified
0.757 0.243 0.000
B37.8 Candidiasis of other sites
0.755 0.245 0.000
R42 Dizziness and giddiness
0.755 0.245 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.754 0.245 0.000
I72.4 Aneurysm of artery of lower extremity
0.752 0.248 0.000
G90 Disorders of autonomic nervous system
0.752 0.248 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.752 0.248 0.000
M79.66 Pain in limb (Lower leg)
0.750 0.250 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.748 0.251 0.000
E00-E07 Disorders of thyroid gland
0.747 0.253 0.000
H43-H45 Disorders of vitreous body and globe
0.747 0.253 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.743 0.257 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.739 0.261 0.000
M20-M25 Other joint disorders
0.738 0.262 0.000
M53 Other dorsopathies, not elsewhere classified
0.738 0.262 0.000
N20.2 Calculus of kidney with calculus of ureter
0.738 0.262 0.000
I86 Varicose veins of other sites
0.738 0.262 0.000
M45 Ankylosing spondylitis
0.737 0.263 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.736 0.264 0.000
M50.2 Other cervical disk displacement
0.735 0.265 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.734 0.266 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.732 0.267 0.000
E28 Ovarian dysfunction
0.730 0.270 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.730 0.270 0.000
M75.9 Shoulder lesion, unspecified
0.728 0.272 0.000
W19 Unspecified fall
0.728 0.272 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.726 0.274 0.000
M79.7 Fibromyalgia
0.725 0.274 0.000
G41 Status epilepticus
0.724 0.275 0.000
T91 Sequelae of injuries of neck and trunk
0.724 0.276 0.000
M50.1 Cervical disk disorder with radiculopathy
0.723 0.276 0.000
T92 Sequelae of injuries of upper limb
0.722 0.278 0.000
S60-S69 Injuries to the wrist and hand
0.722 0.278 0.000
E14.9 Without complications
0.722 0.278 0.000
E65 Localised adiposity
0.720 0.280 0.000
Q80-Q89 Other congenital malformations
0.719 0.281 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.719 0.281 0.000
Q50-Q56 Congenital malformations of genital organs
0.719 0.281 0.000
E27.1 Primary adrenocortical insufficiency
0.719 0.281 0.000
E22 Hyperfunction of pituitary gland
0.718 0.282 0.000
M54.3 Sciatica
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
T90 Sequelae of injuries of head
0.716 0.284 0.000
I88 Nonspecific lymphadenitis
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
N10-N16 Renal tubulo-interstitial diseases
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y95 Nosocomial condition
0.714 0.286 0.000
M54.57 Low back pain (Lumbosacral region)
0.714 0.286 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
B35 Dermatophytosis
0.712 0.288 0.000
I73.8 Other specified peripheral vascular diseases
0.712 0.288 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.711 0.289 0.000
E50-E64 Other nutritional deficiencies
0.711 0.289 0.000
G20-G26 Extrapyramidal and movement disorders
0.711 0.289 0.000
G61.0 Guillain-Barre syndrome
0.710 0.290 0.000
R36 Urethral discharge
0.710 0.290 0.000
R34 Anuria and oliguria
0.710 0.290 0.000
R44.3 Hallucinations, unspecified
0.709 0.291 0.000
M46 Other inflammatory spondylopathies
0.709 0.291 0.000
G40.8 Other epilepsy
0.709 0.291 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.709 0.291 0.000
G40.5 Special epileptic syndromes
0.709 0.291 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.709 0.291 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.709 0.291 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.708 0.292 0.000
E13 Other specified diabetes mellitus
0.708 0.292 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.708 0.292 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.708 0.292 0.000
G92 Toxic encephalopathy
0.708 0.292 0.000
M43 Other deforming dorsopathies
0.708 0.292 0.000
M90 Osteopathies in diseases classified elsewhere
0.707 0.293 0.000
S20 Superficial injury of thorax
0.706 0.294 0.000
I05-I09 Chronic rheumatic heart diseases
0.706 0.294 0.000
S42 Fracture of shoulder and upper arm
0.705 0.295 0.000
G30-G32 Other degenerative diseases of the nervous system
0.705 0.295 0.000
E83.5 Disorders of calcium metabolism
0.704 0.296 0.000
Q60-Q64 Congenital malformations of the urinary system
0.703 0.297 0.000
R50-R69 General symptoms and signs
0.703 0.297 0.000
E85 Amyloidosis
0.702 0.298 0.000
E84 Cystic fibrosis
0.702 0.298 0.000
E79 Disorders of purine and pyrimidine metabolism
0.702 0.298 0.000
E77 Disorders of glycoprotein metabolism
0.702 0.298 0.000
E76 Disorders of glycosaminoglycan metabolism
0.702 0.298 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.702 0.298 0.000
E74 Other disorders of carbohydrate metabolism
0.702 0.298 0.000
E73 Lactose intolerance
0.702 0.298 0.000
E72 Other disorders of amino-acid metabolism
0.702 0.298 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.702 0.298 0.000
E70 Disorders of aromatic amino-acid metabolism
0.702 0.298 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.702 0.298 0.000
I60-I69 Cerebrovascular diseases
0.702 0.298 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.701 0.299 0.000
H53-H54 Visual disturbances and blindness
0.700 0.300 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.699 0.301 0.000
M76 Enthesopathies of lower limb, excluding foot
0.698 0.302 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.698 0.302 0.000
M71 Other bursopathies
0.698 0.302 0.000
M47.1 Other spondylosis with myelopathy
0.697 0.302 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.697 0.303 0.000
M50.0 Cervical disk disorder with myelopathy
0.697 0.303 0.000
M77 Other enthesopathies
0.697 0.303 0.000
M49 Spondylopathies in diseases classified elsewhere
0.697 0.303 0.000
I78.1 Naevus, nonneoplastic
0.697 0.303 0.000
M41 Scoliosis
0.696 0.304 0.000
M65.3 Trigger finger
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.695 0.305 0.000
I74.5 Embolism and thrombosis of iliac artery
0.694 0.305 0.000
R47 Speech disturbances, not elsewhere classified
0.694 0.306 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.693 0.307 0.000
T79-T79 Certain early complications of trauma
0.692 0.308 0.000
H43 Disorders of vitreous body
0.692 0.308 0.000
G96 Other disorders of central nervous system
0.690 0.310 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.690 0.310 0.000
M79.63 Pain in limb (Forearm)
0.690 0.310 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.689 0.310 0.000
E78.2 Mixed hyperlipidaemia
0.689 0.311 0.000
O36 Maternal care for other known or suspected foetal problems
0.688 0.312 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.687 0.313 0.000
M79.1 Myalgia
0.687 0.313 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.687 0.313 0.000
E87.4 Mixed disorder of acid-base balance
0.687 0.313 0.000
E87.3 Alkalosis
0.687 0.313 0.000
E83.3 Disorders of phosphorus metabolism
0.686 0.314 0.000
X60-X84 Intentional self-harm
0.685 0.315 0.000
G70-G73 Diseases of myoneural junction and muscle
0.685 0.315 0.000
I82 Other venous embolism and thrombosis
0.685 0.315 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.685 0.315 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.684 0.316 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.684 0.316 0.000
E83.1 Disorders of iron metabolism
0.684 0.316 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.683 0.317 0.000
R80 Isolated proteinuria
0.683 0.317 0.000
E87.0 Hyperosmolality and hypernatraemia
0.683 0.317 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.683 0.317 0.000
G62.9 Polyneuropathy, unspecified
0.682 0.318 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.682 0.318 0.000
E83.4 Disorders of magnesium metabolism
0.682 0.318 0.000
N00-N08 Glomerular diseases
0.680 0.320 0.000
G93.7 Reye's syndrome
0.680 0.320 0.000
G93.6 Cerebral oedema
0.680 0.320 0.000
G93.5 Compression of brain
0.680 0.320 0.000
G93.2 Benign intracranial hypertension
0.680 0.320 0.000
G93.0 Cerebral cysts
0.680 0.320 0.000
E67 Other hyperalimentation
0.680 0.320 0.000
E68 Sequelae of hyperalimentation
0.680 0.320 0.000
E78.5 Hyperlipidaemia, unspecified
0.678 0.322 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.678 0.322 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.678 0.322 0.000
G62.0 Drug-induced polyneuropathy
0.678 0.322 0.000
S10-S19 Injuries to the neck
0.677 0.323 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.676 0.324 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.676 0.324 0.000
T33-T35 Frostbite
0.675 0.325 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.675 0.325 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.675 0.325 0.000
T00-T07 Injuries involving multiple body regions
0.675 0.325 0.000
R56 Convulsions, not elsewhere classified
0.674 0.326 0.000
E78.8 Other disorders of lipoprotein metabolism
0.674 0.326 0.000
Y35-Y36 Legal intervention and operations of war
0.673 0.326 0.000
Y10-Y34 Event of undetermined intent
0.673 0.326 0.000
Y00-Y09 Assault
0.673 0.326 0.000
X85-X99 Assault
0.673 0.326 0.000
X30-X39 Exposure to forces of nature
0.673 0.326 0.000
X20-X29 Contact with venomous animals and plants
0.673 0.326 0.000
X10-X19 Contact with heat and hot substances
0.673 0.326 0.000
X00-X09 Exposure to smoke, fire and flames
0.673 0.326 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.673 0.326 0.000
W75-W84 Other accidental threats to breathing
0.673 0.326 0.000
W65-W74 Accidental drowning and submersion
0.673 0.326 0.000
W50-W64 Exposure to animate mechanical forces
0.673 0.326 0.000
V98-V99 Other and unspecified transport accidents
0.673 0.326 0.000
V95-V97 Air and space transport accidents
0.673 0.326 0.000
V90-V94 Water transport accidents
0.673 0.326 0.000
V70-V79 Bus occupant injured in transport accident
0.673 0.326 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.673 0.326 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.673 0.326 0.000
V40-V49 Car occupant injured in transport accident
0.673 0.326 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.673 0.326 0.000
V01-V09 Pedestrian injured in transport accident
0.673 0.326 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.673 0.327 0.000
E12 Malnutrition-related diabetes mellitus
0.673 0.327 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.672 0.327 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.672 0.328 0.000
E23 Hypofunction and other disorders of pituitary gland
0.671 0.329 0.000
B99-B99 Other infectious diseases
0.669 0.331 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.669 0.331 0.000
B65-B83 Helminthiases
0.669 0.331 0.000
B50-B64 Protozoal diseases
0.669 0.331 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.669 0.331 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.669 0.331 0.000
A75-A79 Rickettsioses
0.669 0.331 0.000
A70-A74 Other diseases caused by chlamydiae
0.669 0.331 0.000
A65-A69 Other spirochaetal diseases
0.669 0.331 0.000
A20-A28 Certain zoonotic bacterial diseases
0.669 0.331 0.000
A15-A19 Tuberculosis
0.669 0.331 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.669 0.331 0.000
G93.8 Other specified disorders of brain
0.669 0.331 0.000
G44.8 Other specified headache syndromes
0.669 0.331 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.669 0.331 0.000
G44.3 Chronic posttraumatic headache
0.669 0.331 0.000
G44.1 Vascular headache, not elsewhere classified
0.669 0.331 0.000
G44.0 Cluster headache syndrome
0.669 0.331 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.669 0.331 0.000
Q00-Q07 Congenital malformations of the nervous system
0.668 0.332 0.000
M54.8 Other dorsalgia
0.667 0.332 0.000
M54.6 Pain in thoracic spine
0.667 0.332 0.000
M54.0 Panniculitis affecting regions of neck and back
0.667 0.332 0.000
I69 Sequelae of cerebrovascular disease
0.667 0.333 0.000
G91 Hydrocephalus
0.666 0.334 0.000
R82 Other abnormal findings in urine
0.666 0.334 0.000
E66.9 Obesity, unspecified
0.666 0.334 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.666 0.334 0.000
I77.8 Other specified disorders of arteries and arterioles
0.665 0.335 0.000
I77.5 Necrosis of artery
0.665 0.335 0.000
I77.4 Coeliac artery compression syndrome
0.665 0.335 0.000
I77.3 Arterial fibromuscular dysplasia
0.665 0.335 0.000
I77.2 Rupture of artery
0.665 0.335 0.000
I77.0 Arteriovenous fistula, acquired
0.665 0.335 0.000
M72 Fibroblastic disorders
0.665 0.335 0.000
A87 Viral meningitis
0.664 0.336 0.000
E29 Testicular dysfunction
0.663 0.337 0.000
R49 Voice disturbances
0.661 0.339 0.000
M79.9 Soft tissue disorder, unspecified
0.661 0.339 0.000
M79.3 Panniculitis, unspecified
0.661 0.339 0.000
M79.2 Neuralgia and neuritis, unspecified
0.661 0.339 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.660 0.340 0.000
R46 Symptoms and signs involving appearance and behaviour
0.660 0.340 0.000
R43 Disturbances of smell and taste
0.660 0.340 0.000
W17 Other fall from one level to another
0.658 0.342 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.658 0.342 0.000
M47.2 Other spondylosis with radiculopathy
0.657 0.343 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.657 0.343 0.000
E34 Other endocrine disorders
0.657 0.343 0.000
E32 Diseases of thymus
0.657 0.343 0.000
E31 Polyglandular dysfunction
0.657 0.343 0.000
E30 Disorders of puberty, not elsewhere classified
0.657 0.343 0.000
E26 Hyperaldosteronism
0.657 0.343 0.000
E25 Adrenogenital disorders
0.657 0.343 0.000
E24 Cushing's syndrome
0.657 0.343 0.000
E20 Hypoparathyroidism
0.657 0.343 0.000
G60 Hereditary and idiopathic neuropathy
0.657 0.343 0.000
G64 Other disorders of peripheral nervous system
0.657 0.343 0.000
E87.5 Hyperkalaemia
0.656 0.344 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.656 0.344 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.656 0.344 0.000
I71 Aortic aneurysm and dissection
0.655 0.345 0.000
R56.8 Other and unspecified convulsions
0.654 0.346 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.654 0.346 0.000
W20-W49 Exposure to inanimate mechanical forces
0.654 0.346 0.000
M54.50 Low back pain (Multiple sites in spine)
0.654 0.346 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.654 0.346 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.653 0.347 0.000
R44.0 Auditory hallucinations
0.653 0.347 0.000
M89 Other disorders of bone
0.653 0.347 0.000
M50.3 Other cervical disk degeneration
0.653 0.347 0.000
M88 Paget's disease of bone [osteitis deformans]
0.652 0.347 0.000
G95.1 Vascular myelopathies
0.651 0.349 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.650 0.350 0.000
M84 Disorders of continuity of bone
0.650 0.350 0.000
E78.4 Other hyperlipidaemia
0.650 0.350 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.649 0.351 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.649 0.351 0.000
Q35-Q37 Cleft lip and cleft palate
0.649 0.351 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.649 0.351 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.649 0.351 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.649 0.351 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.649 0.351 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.648 0.352 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.648 0.352 0.000
E66.1 Drug-induced obesity
0.648 0.352 0.000
E66.0 Obesity due to excess calories
0.648 0.352 0.000
M75.8 Other shoulder lesions
0.648 0.352 0.000
M87 Osteonecrosis
0.648 0.352 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.648 0.352 0.000
N25-N29 Other disorders of kidney and ureter
0.647 0.353 0.000
I70.9 Generalised and unspecified atherosclerosis
0.647 0.353 0.000
I70.8 Atherosclerosis of other arteries
0.647 0.353 0.000
I70.1 Atherosclerosis of renal artery
0.647 0.353 0.000
I70.0 Atherosclerosis of aorta
0.647 0.353 0.000
Y52 Agents primarily affecting the cardiovascular system
0.647 0.353 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.646 0.354 0.000
M48 Other spondylopathies
0.646 0.354 0.000
R35 Polyuria
0.646 0.354 0.000
E88 Other metabolic disorders
0.646 0.354 0.000
M75.2 Bicipital tendinitis
0.646 0.354 0.000
R45 Symptoms and signs involving emotional state
0.646 0.354 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.646 0.354 0.000
M79.62 Pain in limb (Upper arm)
0.645 0.355 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.645 0.355 0.000
H53 Visual disturbances
0.645 0.355 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.644 0.356 0.000
E11.2 With renal complications
0.644 0.356 0.000
M66 Spontaneous rupture of synovium and tendon
0.644 0.356 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.643 0.357 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.643 0.357 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.642 0.358 0.000
I74.8 Embolism and thrombosis of other arteries
0.642 0.358 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.642 0.358 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.642 0.358 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.642 0.358 0.000
I85.9 Oesophageal varices without bleeding
0.642 0.358 0.000
M65.34 Trigger finger-Hand
0.642 0.358 0.000
R52 Pain, not elsewhere classified
0.641 0.359 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.641 0.359 0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)
0.641 0.359 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.640 0.359 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.640 0.360 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.640 0.360 0.000
M47.84 Other spondylosis (Thoracic region)
0.640 0.360 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.640 0.360 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.640 0.360 0.000
M79.5 Residual foreign body in soft tissue
0.640 0.360 0.000
M54.2 Cervicalgia
0.640 0.360 0.000
N20.9 Urinary calculus, unspecified
0.640 0.360 0.000
Chapter VIII Diseases of the ear and mastoid process
0.638 0.361 0.000
R55 Syncope and collapse
0.638 0.362 0.000
R44.1 Visual hallucinations
0.637 0.363 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.637 0.363 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.637 0.363 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.637 0.363 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.637 0.363 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.637 0.363 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.637 0.363 0.000
M35 Other systemic involvement of connective tissue
0.636 0.363 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.635 0.364 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.635 0.364 0.000
M54.55 Low back pain (Thoracolumbar region)
0.635 0.365 0.000
M54.54 Low back pain-Thoracic
0.635 0.365 0.000
M54.53 Low back pain-Cervicothoracic
0.635 0.365 0.000
M54.52 Low back pain-Cervical
0.635 0.365 0.000
M54.51 Low back pain-Occipit-atl-axl
0.635 0.365 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.635 0.365 0.000
S92 Fracture of foot, except ankle
0.635 0.365 0.000
G93.9 Disorder of brain, unspecified
0.635 0.365 0.000
T66-T78 Other and unspecified effects of external causes
0.634 0.365 0.000
M54.1 Radiculopathy
0.633 0.366 0.000
M50.9 Cervical disk disorder, unspecified
0.633 0.367 0.000
M50.8 Other cervical disk disorders
0.633 0.367 0.000
S20.2 Contusion of thorax
0.633 0.367 0.000
H30-H36 Disorders of choroid and retina
0.632 0.368 0.000
M86 Osteomyelitis
0.632 0.368 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.632 0.368 0.000
B25-B34 Other viral diseases
0.631 0.369 0.000
A04 Other bacterial intestinal infections
0.630 0.370 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.630 0.370 0.000
R94.7 Abnormal results of other endocrine function studies
0.630 0.370 0.000
R94.6 Abnormal results of thyroid function studies
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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