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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117654928
log Bayes Factor = 7.86182
Chromosome 17   position 72,690,643  (GRCh37) Explore rs117654928 on Ensembl!
Variant rs117654928 is part of Cluster X0264

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
H33 Retinal detachments and breaks
0.999 0.001 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.995 0.005 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.994 0.006 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.993 0.007 0.000
E70-E90 Metabolic disorders
0.991 0.009 0.000
H33.2 Serous retinal detachment
0.991 0.009 0.000
O26.9 Pregnancy-related condition, unspecified
0.986 0.014 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.984 0.016 0.000
H33.0 Retinal detachment with retinal break
0.982 0.018 0.000
E10-E14 Diabetes mellitus
0.981 0.019 0.000
M06 Other rheumatoid arthritis
0.981 0.019 0.000
H36 Retinal disorders in diseases classified elsewhere
0.979 0.021 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.979 0.021 0.000
Chapter II Neoplasms
0.979 0.021 0.000
S60-S69 Injuries to the wrist and hand
0.977 0.023 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.975 0.025 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.973 0.027 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.973 0.027 0.000
M05 Seropositive rheumatoid arthritis
0.967 0.033 0.000
H36.0 Diabetic retinopathy
0.965 0.035 0.000
S32 Fracture of lumbar spine and pelvis
0.964 0.036 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.962 0.038 0.000
M06.9 Rheumatoid arthritis, unspecified
0.960 0.040 0.000
M45-M49 Spondylopathies
0.957 0.043 0.000
E20-E35 Disorders of other endocrine glands
0.953 0.047 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.951 0.049 0.000
S32.0 Fracture of lumbar vertebra
0.950 0.050 0.000
E10 Insulin-dependent diabetes mellitus
0.950 0.050 0.000
C92 Myeloid leukaemia
0.948 0.052 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.944 0.056 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.940 0.060 0.000
N18 Chronic renal failure
0.939 0.061 0.000
O26.8 Other specified pregnancy-related conditions
0.939 0.061 0.000
E89.0 Postprocedural hypothyroidism
0.939 0.061 0.000
M86-M90 Other osteopathies
0.937 0.063 0.000
N18.9 Chronic renal failure, unspecified
0.936 0.064 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.927 0.073 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.927 0.073 0.000
N17-N19 Renal failure
0.921 0.079 0.000
M20-M25 Other joint disorders
0.911 0.089 0.000
E88 Other metabolic disorders
0.911 0.089 0.000
Chapter XIV Diseases of the genitourinary system
0.910 0.090 0.000
Chapter VIII Diseases of the ear and mastoid process
0.907 0.093 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.906 0.094 0.000
E10.3 With ophthalmic complications
0.904 0.096 0.000
S61 Open wound of wrist and hand
0.904 0.096 0.000
N18.5 Chronic kidney disease, stage 5
0.902 0.098 0.000
C92.0 Acute myeloid leukaemia
0.900 0.100 0.000
O00-O08 Pregnancy with abortive outcome
0.900 0.100 0.000
H34 Retinal vascular occlusions
0.899 0.100 0.000
M13 Other arthritis
0.893 0.107 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.888 0.112 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.886 0.114 0.000
H65-H75 Diseases of middle ear and mastoid
0.882 0.118 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.878 0.122 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.877 0.123 0.000
E11 Non-insulin-dependent diabetes mellitus
0.877 0.123 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.877 0.123 0.000
H40-H42 Glaucoma
0.876 0.124 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.868 0.132 0.000
E27 Other disorders of adrenal gland
0.865 0.135 0.000
M22 Disorders of patella
0.864 0.136 0.000
M80-M85 Disorders of bone density and structure
0.857 0.143 0.000
M45 Ankylosing spondylitis
0.857 0.143 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.857 0.143 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.855 0.145 0.000
C91 Lymphoid leukaemia
0.854 0.146 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.853 0.147 0.000
E87.5 Hyperkalaemia
0.852 0.148 0.000
S61.0 Open wound of finger(s) without damage to nail
0.848 0.152 0.000
N18.3 Chronic kidney disease, stage 3
0.846 0.154 0.000
C01 Malignant neoplasm of base of tongue
0.843 0.157 0.000
M48 Other spondylopathies
0.843 0.157 0.000
E11.3 With ophthalmic complications
0.842 0.158 0.000
M88 Paget's disease of bone [osteitis deformans]
0.839 0.161 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.834 0.166 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.830 0.170 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.828 0.172 0.000
H65 Nonsuppurative otitis media
0.826 0.174 0.000
C92.1 Chronic myeloid leukaemia
0.819 0.181 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.818 0.182 0.000
H55-H59 Other disorders of eye and adnexa
0.817 0.183 0.000
E23 Hypofunction and other disorders of pituitary gland
0.817 0.183 0.000
O02 Other abnormal products of conception
0.816 0.184 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.807 0.193 0.000
M10 Gout
0.805 0.195 0.000
N18.0 End-stage renal disease
0.805 0.195 0.000
M65-M68 Disorders of synovium and tendon
0.804 0.196 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.801 0.199 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.801 0.199 0.000
O28 Abnormal findings on antenatal screening of mother
0.800 0.199 0.000
H20 Iridocyclitis
0.800 0.200 0.000
E83 Disorders of mineral metabolism
0.800 0.200 0.000
C83.3 Large cell (diffuse)
0.798 0.201 0.000
H74 Other disorders of middle ear and mastoid
0.796 0.204 0.000
M25 Other joint disorders, not elsewhere classified
0.793 0.207 0.000
H18 Other disorders of cornea
0.789 0.211 0.000
E10.1 With ketoacidosis
0.788 0.212 0.000
N00-N08 Glomerular diseases
0.788 0.212 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.788 0.212 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.788 0.212 0.000
E40-E46 Malnutrition
0.787 0.213 0.000
H40 Glaucoma
0.787 0.213 0.000
D00-D09 In situ neoplasms
0.787 0.213 0.000
E89.2 Postprocedural hypoparathyroidism
0.786 0.214 0.000
C64-C68 Malignant neoplasms of urinary tract
0.786 0.214 0.000
M21 Other acquired deformities of limbs
0.785 0.215 0.000
M06.3 Rheumatoid nodule
0.785 0.215 0.000
H21 Other disorders of iris and ciliary body
0.784 0.216 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.784 0.216 0.000
E20 Hypoparathyroidism
0.783 0.217 0.000
C85.1 B-cell lymphoma, unspecified
0.783 0.217 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.783 0.217 0.000
C88 Malignant immunoproliferative diseases
0.781 0.219 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
O20 Haemorrhage in early pregnancy
0.776 0.224 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.775 0.225 0.000
M22.4 Chondromalacia patellae
0.775 0.225 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.775 0.225 0.000
E11.5 With peripheral circulatory complications
0.775 0.225 0.000
M06.4 Inflammatory polyarthropathy
0.774 0.226 0.000
H34.2 Other retinal artery occlusions
0.774 0.226 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.773 0.227 0.000
H33.1 Retinoschisis and retinal cysts
0.772 0.228 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.770 0.230 0.000
M88.9 Paget's disease of bone, unspecified
0.769 0.231 0.000
E50-E64 Other nutritional deficiencies
0.766 0.234 0.000
H57 Other disorders of eye and adnexa
0.762 0.237 0.000
M89 Other disorders of bone
0.762 0.238 0.000
C00 Malignant neoplasm of lip
0.760 0.240 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.760 0.240 0.000
Chapter XXII Codes for special purposes
0.759 0.241 0.000
M13.9 Arthritis, unspecified
0.759 0.241 0.000
S32.5 Fracture of pubis
0.759 0.241 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.758 0.242 0.000
O02.1 Missed abortion
0.757 0.243 0.000
M49 Spondylopathies in diseases classified elsewhere
0.755 0.245 0.000
C77.2 Intra-abdominal lymph nodes
0.754 0.246 0.000
H34.8 Other retinal vascular occlusions
0.754 0.246 0.000
H31 Other disorders of choroid
0.753 0.247 0.000
M07 Psoriatic and enteropathic arthropathies
0.753 0.247 0.000
H33.4 Traction detachment of retina
0.752 0.248 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.752 0.248 0.000
H16 Keratitis
0.752 0.248 0.000
E10.0 With coma
0.751 0.249 0.000
O00 Ectopic pregnancy
0.750 0.250 0.000
M24 Other specific joint derangements
0.748 0.251 0.000
M13.0 Polyarthritis, unspecified
0.748 0.252 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.745 0.255 0.000
H65.4 Other chronic nonsuppurative otitis media
0.745 0.255 0.000
E83.5 Disorders of calcium metabolism
0.745 0.255 0.000
M31 Other necrotising vasculopathies
0.744 0.256 0.000
M60-M63 Disorders of muscles
0.743 0.257 0.000
C83.0 Small cell (diffuse)
0.743 0.257 0.000
C81 Hodgkin's disease
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.741 0.259 0.000
C95 Leukaemia of unspecified cell type
0.741 0.259 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.737 0.263 0.000
M48.0 Spinal stenosis
0.737 0.263 0.000
E10.9 Without complications
0.736 0.264 0.000
N18.4 Chronic kidney disease, stage 4
0.735 0.265 0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)
0.734 0.266 0.000
H33.5 Other retinal detachments
0.734 0.266 0.000
E27.1 Primary adrenocortical insufficiency
0.733 0.267 0.000
E13 Other specified diabetes mellitus
0.733 0.267 0.000
M87 Osteonecrosis
0.730 0.270 0.000
C77.1 Intrathoracic lymph nodes
0.730 0.270 0.000
H57.1 Ocular pain
0.729 0.271 0.000
E27.8 Other specified disorders of adrenal gland
0.729 0.271 0.000
M84 Disorders of continuity of bone
0.728 0.272 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.728 0.272 0.000
O26.2 Pregnancy care of habitual aborter
0.728 0.272 0.000
E85 Amyloidosis
0.728 0.272 0.000
C91.1 Chronic lymphocytic leukaemia
0.727 0.273 0.000
N20-N23 Urolithiasis
0.726 0.274 0.000
C12 Malignant neoplasm of pyriform sinus
0.726 0.274 0.000
O23 Infections of genito-urinary tract in pregnancy
0.725 0.275 0.000
T79-T79 Certain early complications of trauma
0.725 0.275 0.000
E34 Other endocrine disorders
0.724 0.276 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.724 0.276 0.000
S61.8 Open wound of other parts of wrist and hand
0.723 0.277 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.722 0.278 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.721 0.279 0.000
M22.3 Other derangements of patella
0.721 0.279 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.721 0.279 0.000
H17 Corneal scars and opacities
0.720 0.280 0.000
N19 Unspecified renal failure
0.720 0.280 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.719 0.281 0.000
T00-T07 Injuries involving multiple body regions
0.719 0.281 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.718 0.282 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
H30 Chorioretinal inflammation
0.717 0.283 0.000
M12 Other specific arthropathies
0.716 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.283 0.000
M08 Juvenile arthritis
0.716 0.283 0.000
S32.3 Fracture of ilium
0.716 0.284 0.000
E16 Other disorders of pancreatic internal secretion
0.715 0.285 0.000
H40.2 Primary angle-closure glaucoma
0.715 0.285 0.000
O60-O75 Complications of labour and delivery
0.713 0.287 0.000
O29 Complications of anaesthesia during pregnancy
0.713 0.287 0.000
O22 Venous complications in pregnancy
0.713 0.287 0.000
O25 Malnutrition in pregnancy
0.713 0.287 0.000
E23.0 Hypopituitarism
0.712 0.288 0.000
E11.0 With coma
0.712 0.288 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.712 0.288 0.000
O26.5 Maternal hypotension syndrome
0.712 0.288 0.000
O26.4 Herpes gestationis
0.712 0.288 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.712 0.288 0.000
O26.1 Low weight gain in pregnancy
0.712 0.288 0.000
O26.0 Excessive weight gain in pregnancy
0.712 0.288 0.000
H71 Cholesteatoma of middle ear
0.711 0.289 0.000
E84 Cystic fibrosis
0.711 0.289 0.000
E79 Disorders of purine and pyrimidine metabolism
0.711 0.289 0.000
E77 Disorders of glycoprotein metabolism
0.711 0.289 0.000
E76 Disorders of glycosaminoglycan metabolism
0.711 0.289 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.711 0.289 0.000
E74 Other disorders of carbohydrate metabolism
0.711 0.289 0.000
E72 Other disorders of amino-acid metabolism
0.711 0.289 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.711 0.289 0.000
E70 Disorders of aromatic amino-acid metabolism
0.711 0.289 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.711 0.289 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.710 0.290 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.708 0.292 0.000
S20-S29 Injuries to the thorax
0.707 0.293 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.706 0.294 0.000
T33-T35 Frostbite
0.705 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.705 0.295 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.705 0.295 0.000
E89.3 Postprocedural hypopituitarism
0.704 0.296 0.000
E28 Ovarian dysfunction
0.704 0.296 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.704 0.296 0.000
E12 Malnutrition-related diabetes mellitus
0.704 0.296 0.000
M06.8 Other specified rheumatoid arthritis
0.703 0.297 0.000
M06.2 Rheumatoid bursitis
0.703 0.297 0.000
M06.1 Adult-onset Still's disease
0.703 0.297 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.702 0.298 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.702 0.298 0.000
C94 Other leukaemias of specified cell type
0.702 0.298 0.000
C93 Monocytic leukaemia
0.702 0.298 0.000
C86 Other specified types of T/NK-cell lymphoma
0.702 0.298 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.298 0.000
C04 Malignant neoplasm of floor of mouth
0.701 0.299 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.699 0.301 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.699 0.301 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.699 0.301 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.699 0.301 0.000
S65 Injury of blood vessels at wrist and hand level
0.699 0.301 0.000
M90 Osteopathies in diseases classified elsewhere
0.699 0.301 0.000
M40-M43 Deforming dorsopathies
0.699 0.301 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.698 0.302 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.698 0.302 0.000
E89.5 Postprocedural testicular hypofunction
0.698 0.302 0.000
E89.4 Postprocedural ovarian failure
0.698 0.302 0.000
E89.1 Postprocedural hypoinsulinaemia
0.698 0.302 0.000
E29 Testicular dysfunction
0.697 0.302 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.697 0.302 0.000
S37 Injury of urinary and pelvic organs
0.697 0.302 0.000
S36 Injury of intra-abdominal organs
0.697 0.302 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.697 0.302 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.697 0.302 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.697 0.302 0.000
S31 Open wound of abdomen, lower back and pelvis
0.697 0.302 0.000
M14 Arthropathies in other diseases classified elsewhere
0.696 0.304 0.000
O24 Diabetes mellitus in pregnancy
0.695 0.305 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.695 0.305 0.000
M46 Other inflammatory spondylopathies
0.695 0.305 0.000
H40.1 Primary open-angle glaucoma
0.694 0.306 0.000
M00-M03 Infectious arthropathies
0.694 0.306 0.000
C80 Malignant neoplasm without specification of site
0.694 0.306 0.000
H35 Other retinal disorders
0.694 0.306 0.000
M05.8 Other seropositive rheumatoid arthritis
0.693 0.307 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.693 0.307 0.000
M05.2 Rheumatoid vasculitis
0.693 0.307 0.000
M05.1 Rheumatoid lung disease
0.693 0.307 0.000
M05.0 Felty's syndrome
0.693 0.307 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.693 0.307 0.000
S32.2 Fracture of coccyx
0.691 0.308 0.000
S32.1 Fracture of sacrum
0.691 0.308 0.000
H69 Other disorders of Eustachian tube
0.691 0.309 0.000
M25.7 Osteophyte
0.691 0.309 0.000
E10.5 With peripheral circulatory complications
0.689 0.311 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.689 0.311 0.000
E26 Hyperaldosteronism
0.689 0.311 0.000
O85-O92 Complications predominantly related to the puerperium
0.688 0.311 0.000
H73 Other disorders of tympanic membrane
0.687 0.313 0.000
M25.3 Other instability of joint
0.687 0.313 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.687 0.313 0.000
M47 Spondylosis
0.687 0.313 0.000
M22.2 Patellofemoral disorders
0.687 0.313 0.000
N23 Unspecified renal colic
0.686 0.314 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.686 0.314 0.000
S67 Crushing injury of wrist and hand
0.685 0.315 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.685 0.315 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.683 0.317 0.000
E32 Diseases of thymus
0.683 0.317 0.000
E31 Polyglandular dysfunction
0.683 0.317 0.000
E30 Disorders of puberty, not elsewhere classified
0.683 0.317 0.000
E25 Adrenogenital disorders
0.683 0.317 0.000
C91.0 Acute lymphoblastic leukaemia
0.683 0.317 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.681 0.318 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.681 0.318 0.000
H15 Disorders of sclera
0.681 0.318 0.000
S32.01 Fracture of lumbar vertebra (open)
0.681 0.319 0.000
E10.8 With unspecified complications
0.681 0.319 0.000
E10.7 With multiple complications
0.681 0.319 0.000
E10.6 With other specified complications
0.681 0.319 0.000
M82 Osteoporosis in diseases classified elsewhere
0.680 0.320 0.000
C92.9 Myeloid leukaemia, unspecified
0.679 0.321 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.679 0.321 0.000
C92.7 Other myeloid leukaemia
0.679 0.321 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.679 0.321 0.000
C92.5 Acute myelomonocytic leukaemia
0.679 0.321 0.000
C92.4 Acute promyelocytic leukaemia
0.679 0.321 0.000
C92.3 Myeloid sarcoma
0.679 0.321 0.000
C92.2 Subacute myeloid leukaemia
0.679 0.321 0.000
C77.0 Lymph nodes of head, face and neck
0.678 0.322 0.000
E87.0 Hyperosmolality and hypernatraemia
0.677 0.323 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.677 0.323 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.677 0.323 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.677 0.323 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.677 0.323 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.677 0.323 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.677 0.323 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.677 0.323 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.677 0.323 0.000
M86 Osteomyelitis
0.676 0.324 0.000
E73 Lactose intolerance
0.676 0.324 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.676 0.324 0.000
O21 Excessive vomiting in pregnancy
0.676 0.324 0.000
N18.1 Chronic kidney disease, stage 1
0.673 0.326 0.000
C77.9 Lymph node, unspecified
0.673 0.327 0.000
C10 Malignant neoplasm of oropharynx
0.672 0.328 0.000
S61.1 Open wound of finger(s) with damage to nail
0.670 0.330 0.000
H20.8 Other iridocyclitis
0.669 0.331 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.667 0.332 0.000
O80-O84 Delivery
0.667 0.333 0.000
H74.4 Polyp of middle ear
0.666 0.334 0.000
H21.8 Other specified disorders of iris and ciliary body
0.665 0.335 0.000
M65 Synovitis and tenosynovitis
0.665 0.335 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.665 0.335 0.000
C13 Malignant neoplasm of hypopharynx
0.665 0.335 0.000
C11 Malignant neoplasm of nasopharynx
0.665 0.335 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.665 0.335 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.665 0.335 0.000
C05 Malignant neoplasm of palate
0.665 0.335 0.000
C03 Malignant neoplasm of gum
0.665 0.335 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.665 0.335 0.000
M70-M79 Other soft tissue disorders
0.665 0.335 0.000
C83.7 Burkitt's tumour
0.664 0.336 0.000
C83.6 Undifferentiated (diffuse)
0.664 0.336 0.000
C83.5 Lymphoblastic (diffuse)
0.664 0.336 0.000
C83.4 Immunoblastic (diffuse)
0.664 0.336 0.000
C83.2 Mixed small and large cell (diffuse)
0.664 0.336 0.000
C83.1 Small cleaved cell (diffuse)
0.664 0.336 0.000
M91-M94 Chondropathies
0.664 0.336 0.000
E11.8 With unspecified complications
0.664 0.336 0.000
N05 Unspecified nephritic syndrome
0.663 0.337 0.000
E20.9 Hypoparathyroidism, unspecified
0.662 0.338 0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother
0.662 0.338 0.000
S69 Other and unspecified injuries of wrist and hand
0.661 0.339 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.660 0.340 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.659 0.340 0.000
E10.4 With neurological complications
0.658 0.342 0.000
S40-S49 Injuries to the shoulder and upper arm
0.657 0.343 0.000
M81 Osteoporosis without pathological fracture
0.656 0.344 0.000
S60 Superficial injury of wrist and hand
0.653 0.346 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.653 0.347 0.000
M33 Dermatopolymyositis
0.653 0.347 0.000
M32 Systemic lupus erythematosus
0.653 0.347 0.000
M30 Polyarteritis nodosa and related conditions
0.653 0.347 0.000
E88.9 Metabolic disorder, unspecified
0.653 0.347 0.000
E88.8 Other specified metabolic disorders
0.653 0.347 0.000
E88.3 Tumour lysis syndrome
0.653 0.347 0.000
E88.2 Lipomatosis, not elsewhere classified
0.653 0.347 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.653 0.347 0.000
E83.3 Disorders of phosphorus metabolism
0.650 0.350 0.000
H18.4 Corneal degeneration
0.650 0.350 0.000
C84.4 Peripheral T-cell lymphoma
0.649 0.351 0.000
M06.0 Seronegative rheumatoid arthritis
0.649 0.351 0.000
S61.7 Multiple open wounds of wrist and hand
0.649 0.351 0.000
E87.3 Alkalosis
0.648 0.352 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.648 0.352 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.646 0.354 0.000
O07 Failed attempted abortion
0.645 0.355 0.000
O06 Unspecified abortion
0.645 0.355 0.000
O05 Other abortion
0.645 0.355 0.000
O01 Hydatidiform mole
0.645 0.355 0.000
O20.0 Threatened abortion
0.645 0.355 0.000
N18.8 Other chronic renal failure
0.645 0.355 0.000
M22.8 Other disorders of patella
0.645 0.355 0.000
H34.9 Retinal vascular occlusion, unspecified
0.645 0.355 0.000
H34.1 Central retinal artery occlusion
0.645 0.355 0.000
H34.0 Transient retinal artery occlusion
0.645 0.355 0.000
C60-C63 Malignant neoplasms of male genital organs
0.645 0.355 0.000
M25.9 Joint disorder, unspecified
0.645 0.355 0.000
H18.9 Disorder of cornea, unspecified
0.644 0.356 0.000
M06.34 Rheumatoid nodule (Hand)
0.644 0.356 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.644 0.356 0.000
E55 Vitamin D deficiency
0.642 0.357 0.000
C00.0 External upper lip
0.641 0.359 0.000
N03 Chronic nephritic syndrome
0.641 0.359 0.000
M13.8 Other specified arthritis
0.640 0.360 0.000
M13.1 Monoarthritis, not elsewhere classified
0.640 0.360 0.000
T23 Burn and corrosion of wrist and hand
0.640 0.360 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.640 0.360 0.000
S32.4 Fracture of acetabulum
0.639 0.361 0.000
E14 Unspecified diabetes mellitus
0.639 0.361 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.639 0.361 0.000
M34 Systemic sclerosis
0.639 0.361 0.000
M25.78 Osteophyte (Other)
0.638 0.362 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.638 0.362 0.000
H65.3 Chronic mucoid otitis media
0.638 0.362 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.638 0.362 0.000
E24 Cushing's syndrome
0.638 0.362 0.000
M10.0 Idiopathic gout
0.637 0.363 0.000
S64 Injury of nerves at wrist and hand level
0.636 0.364 0.000
E87.4 Mixed disorder of acid-base balance
0.636 0.364 0.000
S10-S19 Injuries to the neck
0.635 0.364 0.000
H20.9 Iridocyclitis, unspecified
0.635 0.365 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.634 0.365 0.000
E46 Unspecified protein-energy malnutrition
0.634 0.366 0.000
M24.0 Loose body in joint
0.634 0.366 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.634 0.366 0.000
H33.3 Retinal breaks without detachment
0.634 0.366 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.633 0.367 0.000
H70 Mastoiditis and related conditions
0.633 0.367 0.000
H68 Eustachian salpingitis and obstruction
0.633 0.367 0.000
H67 Otitis media in diseases classified elsewhere
0.633 0.367 0.000
C07 Malignant neoplasm of parotid gland
0.633 0.367 0.000
C77.5 Intrapelvic lymph nodes
0.632 0.368 0.000
H60-H62 Diseases of external ear
0.632 0.368 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.631 0.369 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.631 0.369 0.000
C09 Malignant neoplasm of tonsil
0.630 0.370 0.000
Chapter V Mental and behavioural disorders
0.630 0.370 0.000
E22 Hyperfunction of pituitary gland
0.629 0.370 0.000
M21.0 Valgus deformity, not elsewhere classified
0.629 0.371 0.000
E11.7 With multiple complications
0.629 0.371 0.000
H42 Glaucoma in diseases classified elsewhere
0.628 0.372 0.000
E27.9 Disorder of adrenal gland, unspecified
0.627 0.372 0.000
H52 Disorders of refraction and accommodation
0.627 0.373 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.626 0.374 0.000
M21.4 Flat foot [pes planus] (acquired)
0.626 0.374 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.625 0.375 0.000
T31 Burns classified according to extent of body surface involved
0.625 0.375 0.000
S50-S59 Injuries to the elbow and forearm
0.624 0.376 0.000
H35.8 Other specified retinal disorders
0.624 0.376 0.000
S92 Fracture of foot, except ankle
0.623 0.377 0.000
S71 Open wound of hip and thigh
0.623 0.377 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.622 0.378 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.622 0.378 0.000
C85.0 Lymphosarcoma
0.622 0.378 0.000
H25-H28 Disorders of lens
0.622 0.378 0.000
M89.9 Disorder of bone, unspecified
0.621 0.379 0.000
N04 Nephrotic syndrome
0.621 0.379 0.000
C80.9 Malignant neoplasm, unspecified
0.621 0.379 0.000
H16.9 Keratitis, unspecified
0.620 0.380 0.000
M13.93 Arthritis, unspecified (Forearm)
0.620 0.380 0.000
E27.5 Adrenomedullary hyperfunction
0.620 0.380 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.620 0.380 0.000
E27.2 Addisonian crisis
0.620 0.380 0.000
E27.0 Other adrenocortical overactivity
0.620 0.380 0.000
Q80-Q89 Other congenital malformations
0.620 0.380 0.000
O00.1 Tubal pregnancy
0.620 0.380 0.000
M22.1 Recurrent subluxation of patella
0.619 0.380 0.000
M22.9 Disorder of patella, unspecified
0.619 0.380 0.000
M22.0 Recurrent dislocation of patella
0.619 0.380 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.619 0.380 0.000
Q00-Q07 Congenital malformations of the nervous system
0.618 0.382 0.000
T20 Burn and corrosion of head and neck
0.618 0.382 0.000
M10.9 Gout, unspecified
0.617 0.383 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.616 0.384 0.000
H65.2 Chronic serous otitis media
0.616 0.384 0.000
D04 Carcinoma in situ of skin
0.616 0.384 0.000
M85 Other disorders of bone density and structure
0.615 0.385 0.000
M83 Adult osteomalacia
0.615 0.385 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.614 0.386 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.614 0.386 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.614 0.386 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.614 0.386 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.614 0.386 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.614 0.386 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.614 0.386 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.614 0.386 0.000
H40.8 Other glaucoma
0.614 0.386 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.614 0.386 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.613 0.387 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.613 0.387 0.000
C91.9 Lymphoid leukaemia, unspecified
0.612 0.388 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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