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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117664943
log Bayes Factor = 16.2944
Chromosome 16   position 52,408,480  (GRCh37) Explore rs117664943 on Ensembl!
Variant rs117664943 is part of Cluster X0290

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.997 0.003 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.996 0.004 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.987 0.013 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.983 0.017 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.981 0.019 0.000
D10-D36 Benign neoplasms
0.980 0.020 0.000
I20 Angina pectoris
0.980 0.020 0.000
Z72 Problems related to lifestyle
0.979 0.021 0.000
Z72.0 Tobacco use
0.975 0.025 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.974 0.026 0.000
L20-L30 Dermatitis and eczema
0.963 0.037 0.000
M20-M25 Other joint disorders
0.960 0.040 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.959 0.041 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.955 0.045 0.000
I30-I52 Other forms of heart disease
0.953 0.047 0.000
Z95.1 Presence of aortocoronary bypass graft
0.952 0.048 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.948 0.052 0.000
C79 Secondary malignant neoplasm of other sites
0.946 0.054 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.945 0.055 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.943 0.057 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.942 0.058 0.000
Chapter V Mental and behavioural disorders
0.942 0.058 0.000
I20.0 Unstable angina
0.942 0.058 0.000
N10-N16 Renal tubulo-interstitial diseases
0.941 0.059 0.000
L30 Other dermatitis
0.931 0.069 0.000
Chapter I Certain infectious and parasitic diseases
0.930 0.070 0.000
I10-I15 Hypertensive diseases
0.929 0.071 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.923 0.077 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.922 0.078 0.000
Z95.0 Presence of cardiac pacemaker
0.922 0.078 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.921 0.079 0.000
N20-N23 Urolithiasis
0.920 0.080 0.000
N95 Menopausal and other perimenopausal disorders
0.916 0.084 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.914 0.086 0.000
M23 Internal derangement of knee
0.911 0.089 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.910 0.090 0.000
I25.1 Atherosclerotic heart disease
0.908 0.092 0.000
N13 Obstructive and reflux uropathy
0.908 0.092 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.904 0.096 0.000
N95.0 Postmenopausal bleeding
0.897 0.103 0.000
D12.2 Ascending colon
0.896 0.104 0.000
Z95.4 Presence of other heart-valve replacement
0.896 0.104 0.000
Chapter XX External causes of morbidity and mortality
0.894 0.106 0.000
M65-M68 Disorders of synovium and tendon
0.893 0.107 0.000
L30.9 Dermatitis, unspecified
0.893 0.107 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.887 0.113 0.000
M05-M14 Inflammatory polyarthropathies
0.886 0.114 0.000
I10 Essential (primary) hypertension
0.884 0.116 0.000
Z88.0 Personal history of allergy to penicillin
0.880 0.120 0.000
Chapter X Diseases of the respiratory system
0.880 0.120 0.000
Z88.6 Personal history of allergy to analgesic agent
0.879 0.121 0.000
N94.1 Dyspareunia
0.875 0.125 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.875 0.125 0.000
N20 Calculus of kidney and ureter
0.874 0.126 0.000
C51-C58 Malignant neoplasms of female genital organs
0.873 0.126 0.000
L40-L45 Papulosquamous disorders
0.873 0.127 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.873 0.127 0.000
M45-M49 Spondylopathies
0.873 0.127 0.000
R30-R39 Symptoms and signs involving the urinary system
0.871 0.129 0.000
I42 Cardiomyopathy
0.870 0.130 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.868 0.132 0.000
I35 Nonrheumatic aortic valve disorders
0.867 0.133 0.000
I20.9 Angina pectoris, unspecified
0.865 0.135 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.863 0.137 0.000
Z97 Presence of other devices
0.863 0.137 0.000
D12.4 Descending colon
0.863 0.137 0.000
D12.5 Sigmoid colon
0.862 0.138 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.862 0.138 0.000
B25-B34 Other viral diseases
0.859 0.141 0.000
Z12 Special screening examination for neoplasms
0.857 0.143 0.000
N99-N99 Other disorders of the genitourinary system
0.852 0.148 0.000
M50-M54 Other dorsopathies
0.847 0.153 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.845 0.155 0.000
Z95.2 Presence of prosthetic heart valve
0.843 0.157 0.000
I50 Heart failure
0.841 0.159 0.000
M15-M19 Arthrosis
0.839 0.161 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.828 0.172 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.825 0.175 0.000
Chapter VIII Diseases of the ear and mastoid process
0.821 0.179 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.820 0.180 0.000
B35-B49 Mycoses
0.819 0.181 0.000
C56 Malignant neoplasm of ovary
0.817 0.183 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.816 0.184 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.813 0.187 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.812 0.188 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.812 0.188 0.000
D12.0 Caecum
0.811 0.189 0.000
C43 Malignant melanoma of skin
0.811 0.189 0.000
R00 Abnormalities of heart beat
0.810 0.190 0.000
B34 Viral infection of unspecified site
0.808 0.192 0.000
J30-J39 Other diseases of upper respiratory tract
0.807 0.193 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.807 0.193 0.000
L60-L75 Disorders of skin appendages
0.806 0.194 0.000
Z74 Problems related to care-provider dependency
0.801 0.199 0.000
R26 Abnormalities of gait and mobility
0.801 0.199 0.000
Z95.3 Presence of xenogenic heart valve
0.801 0.199 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.800 0.200 0.000
F30-F39 Mood [affective] disorders
0.798 0.202 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.796 0.204 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.796 0.204 0.000
M17 Gonarthrosis [arthrosis of knee]
0.794 0.206 0.000
L40 Psoriasis
0.794 0.206 0.000
C44 Other malignant neoplasms of skin
0.793 0.207 0.000
R20 Disturbances of skin sensation
0.793 0.207 0.000
R47-R49 Symptoms and signs involving speech and voice
0.793 0.207 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.792 0.208 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.790 0.210 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.789 0.211 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.786 0.214 0.000
D22 Melanocytic naevi
0.786 0.214 0.000
D12.8 Rectum
0.785 0.215 0.000
R07 Pain in throat and chest
0.785 0.215 0.000
R06 Abnormalities of breathing
0.785 0.215 0.000
R22.2 Localised swelling, mass and lump, trunk
0.785 0.215 0.000
N13.3 Other and unspecified hydronephrosis
0.784 0.216 0.000
I49 Other cardiac arrhythmias
0.783 0.217 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.782 0.218 0.000
D25 Leiomyoma of uterus
0.780 0.220 0.000
M65 Synovitis and tenosynovitis
0.779 0.221 0.000
R04 Haemorrhage from respiratory passages
0.778 0.222 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.778 0.222 0.000
N20.0 Calculus of kidney
0.778 0.222 0.000
L30.8 Other specified dermatitis
0.777 0.223 0.000
I25.5 Ischaemic cardiomyopathy
0.777 0.223 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.775 0.225 0.000
I05-I09 Chronic rheumatic heart diseases
0.774 0.226 0.000
L27 Dermatitis due to substances taken internally
0.774 0.226 0.000
C78.0 Secondary malignant neoplasm of lung
0.774 0.226 0.000
Z73 Problems related to life-management difficulty
0.773 0.227 0.000
C78.7 Secondary malignant neoplasm of liver
0.773 0.227 0.000
M24 Other specific joint derangements
0.772 0.228 0.000
B34.9 Viral infection, unspecified
0.772 0.228 0.000
I42.0 Dilated cardiomyopathy
0.770 0.230 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.770 0.230 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.769 0.231 0.000
D12.6 Colon, unspecified
0.767 0.233 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.766 0.234 0.000
D32 Benign neoplasm of meninges
0.766 0.234 0.000
R31 Unspecified haematuria
0.764 0.236 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.764 0.236 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.761 0.239 0.000
N20.2 Calculus of kidney with calculus of ureter
0.761 0.239 0.000
C64-C68 Malignant neoplasms of urinary tract
0.760 0.240 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.760 0.240 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.759 0.241 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.759 0.241 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.758 0.242 0.000
M31 Other necrotising vasculopathies
0.758 0.242 0.000
N89 Other noninflammatory disorders of vagina
0.757 0.242 0.000
L40.9 Psoriasis, unspecified
0.757 0.243 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.754 0.246 0.000
M80-M85 Disorders of bone density and structure
0.753 0.247 0.000
I60-I69 Cerebrovascular diseases
0.750 0.250 0.000
L29 Pruritus
0.749 0.250 0.000
C79.2 Secondary malignant neoplasm of skin
0.749 0.251 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.748 0.252 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.747 0.253 0.000
M20 Acquired deformities of fingers and toes
0.745 0.254 0.000
R18 Ascites
0.745 0.255 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.743 0.257 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.742 0.258 0.000
M54 Dorsalgia
0.741 0.259 0.000
C80 Malignant neoplasm without specification of site
0.741 0.259 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.741 0.259 0.000
R32 Unspecified urinary incontinence
0.740 0.260 0.000
F80-F89 Disorders of psychological development
0.740 0.260 0.000
B37 Candidiasis
0.739 0.261 0.000
M40-M43 Deforming dorsopathies
0.738 0.262 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.738 0.262 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.737 0.263 0.000
Z91.5 Personal history of self-harm
0.736 0.264 0.000
R80 Isolated proteinuria
0.734 0.266 0.000
Z87 Personal history of other diseases and conditions
0.734 0.266 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.733 0.267 0.000
L50-L54 Urticaria and erythema
0.733 0.267 0.000
Z75 Problems related to medical facilities and other health care
0.733 0.267 0.000
I20.8 Other forms of angina pectoris
0.732 0.268 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.728 0.272 0.000
R21 Rash and other nonspecific skin eruption
0.728 0.272 0.000
N86 Erosion and ectropion of cervix uteri
0.728 0.272 0.000
R50-R69 General symptoms and signs
0.727 0.273 0.000
F99-F99 Unspecified mental disorder
0.727 0.273 0.000
N13.4 Hydroureter
0.727 0.273 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.726 0.273 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.726 0.274 0.000
M22 Disorders of patella
0.726 0.274 0.000
M67 Other disorders of synovium and tendon
0.726 0.274 0.000
Z91.6 Personal history of other physical trauma
0.724 0.276 0.000
M21 Other acquired deformities of limbs
0.724 0.276 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.723 0.276 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.723 0.276 0.000
M46 Other inflammatory spondylopathies
0.723 0.277 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.723 0.277 0.000
M17.1 Other primary gonarthrosis
0.723 0.277 0.000
N25-N29 Other disorders of kidney and ureter
0.720 0.279 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.720 0.279 0.000
I35.0 Aortic (valve) stenosis
0.720 0.280 0.000
V10-V19 Pedal cyclist injured in transport accident
0.719 0.280 0.000
R05 Cough
0.719 0.281 0.000
I22 Subsequent myocardial infarction
0.718 0.281 0.000
N93 Other abnormal uterine and vaginal bleeding
0.718 0.282 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.718 0.282 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.718 0.282 0.000
N23 Unspecified renal colic
0.718 0.282 0.000
O47 False labour
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M86-M90 Other osteopathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
Z83 Family history of other specific disorders
0.716 0.284 0.000
Z89 Acquired absence of limb
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
J09-J18 Influenza and pneumonia
0.715 0.285 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.715 0.285 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
I25.4 Coronary artery aneurysm
0.715 0.285 0.000
I25.3 Aneurysm of heart
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.715 0.285 0.000
J00-J06 Acute upper respiratory infections
0.715 0.285 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.714 0.286 0.000
R22.0 Localised swelling, mass and lump, head
0.713 0.287 0.000
Z76 Persons encountering health services in other circumstances
0.711 0.289 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.711 0.289 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.710 0.289 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.710 0.289 0.000
I21 Acute myocardial infarction
0.710 0.290 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.709 0.291 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.709 0.291 0.000
J36 Peritonsillar abscess
0.708 0.292 0.000
L10-L14 Bullous disorders
0.707 0.292 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.707 0.292 0.000
Z88.2 Personal history of allergy to sulphonamides
0.707 0.293 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.706 0.294 0.000
M13 Other arthritis
0.704 0.296 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.703 0.297 0.000
J32 Chronic sinusitis
0.703 0.297 0.000
M48 Other spondylopathies
0.703 0.297 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.703 0.297 0.000
D31 Benign neoplasm of eye and adnexa
0.703 0.297 0.000
D30 Benign neoplasm of urinary organs
0.703 0.297 0.000
D29 Benign neoplasm of male genital organs
0.703 0.297 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.703 0.297 0.000
D26 Other benign neoplasms of uterus
0.703 0.297 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.703 0.297 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.703 0.297 0.000
D19 Benign neoplasm of mesothelial tissue
0.703 0.297 0.000
D16 Benign neoplasm of bone and articular cartilage
0.703 0.297 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.703 0.297 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.703 0.297 0.000
D11 Benign neoplasm of major salivary glands
0.703 0.297 0.000
D10 Benign neoplasm of mouth and pharynx
0.703 0.297 0.000
I20.1 Angina pectoris with documented spasm
0.703 0.297 0.000
D34 Benign neoplasm of thyroid gland
0.702 0.298 0.000
M05 Seropositive rheumatoid arthritis
0.702 0.298 0.000
Z72.9 Problem related to lifestyle, unspecified
0.702 0.298 0.000
Z72.8 Other problems related to lifestyle
0.702 0.298 0.000
Z72.6 Gambling and betting
0.702 0.298 0.000
Z72.5 High-risk sexual behaviour
0.702 0.298 0.000
Z72.4 Inappropriate diet and eating habits
0.702 0.298 0.000
Z72.3 Lack of physical exercise
0.702 0.298 0.000
Z72.2 Drug use
0.702 0.298 0.000
R30 Pain associated with micturition
0.700 0.300 0.000
D12.9 Anus and anal canal
0.698 0.301 0.000
D12.1 Appendix
0.698 0.301 0.000
O60-O75 Complications of labour and delivery
0.698 0.302 0.000
N00-N08 Glomerular diseases
0.698 0.302 0.000
D25.9 Leiomyoma of uterus, unspecified
0.698 0.302 0.000
I50.0 Congestive heart failure
0.697 0.303 0.000
R06.8 Other and unspecified abnormalities of breathing
0.697 0.303 0.000
Z99.3 Dependence on wheelchair
0.696 0.304 0.000
R00.1 Bradycardia, unspecified
0.696 0.304 0.000
F41 Other anxiety disorders
0.695 0.304 0.000
R04.0 Epistaxis
0.694 0.306 0.000
J95-J99 Other diseases of the respiratory system
0.694 0.306 0.000
Z94 Transplanted organ and tissue status
0.694 0.306 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.693 0.307 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.693 0.307 0.000
Z98 Other postsurgical states
0.692 0.308 0.000
F32 Depressive episode
0.692 0.308 0.000
N20.1 Calculus of ureter
0.691 0.309 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.691 0.309 0.000
L28 Lichen simplex chronicus and prurigo
0.690 0.310 0.000
L25 Unspecified contact dermatitis
0.690 0.310 0.000
L24 Irritant contact dermatitis
0.690 0.310 0.000
L23 Allergic contact dermatitis
0.690 0.310 0.000
L21 Seborrhoeic dermatitis
0.690 0.310 0.000
L20 Atopic dermatitis
0.690 0.310 0.000
L26 Exfoliative dermatitis
0.690 0.310 0.000
L22 Diaper [napkin] dermatitis
0.690 0.310 0.000
Z04 Examination and observation for other reasons
0.690 0.310 0.000
I24 Other acute ischaemic heart diseases
0.690 0.310 0.000
I34 Nonrheumatic mitral valve disorders
0.690 0.310 0.000
A30-A49 Other bacterial diseases
0.690 0.310 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.688 0.311 0.000
M34 Systemic sclerosis
0.688 0.311 0.000
M33 Dermatopolymyositis
0.688 0.311 0.000
M32 Systemic lupus erythematosus
0.688 0.311 0.000
M30 Polyarteritis nodosa and related conditions
0.688 0.311 0.000
R23 Other skin changes
0.688 0.312 0.000
D12.3 Transverse colon
0.688 0.312 0.000
Z85 Personal history of malignant neoplasm
0.687 0.313 0.000
I38 Endocarditis, valve unspecified
0.687 0.313 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.686 0.314 0.000
N94.6 Dysmenorrhoea, unspecified
0.685 0.315 0.000
Z10 Routine general health check-up of defined subpopulation
0.685 0.315 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.684 0.315 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.684 0.316 0.000
Y43 Primarily systemic agents
0.684 0.316 0.000
I42.9 Cardiomyopathy, unspecified
0.684 0.316 0.000
I52 Other heart disorders in diseases classified elsewhere
0.683 0.317 0.000
I48 Atrial fibrillation and flutter
0.683 0.317 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.683 0.317 0.000
I41 Myocarditis in diseases classified elsewhere
0.683 0.317 0.000
I40 Acute myocarditis
0.683 0.317 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.683 0.317 0.000
I37 Pulmonary valve disorders
0.683 0.317 0.000
I36 Nonrheumatic tricuspid valve disorders
0.683 0.317 0.000
I33 Acute and subacute endocarditis
0.683 0.317 0.000
I32 Pericarditis in diseases classified elsewhere
0.683 0.317 0.000
I30 Acute pericarditis
0.683 0.317 0.000
D36 Benign neoplasm of other and unspecified sites
0.682 0.318 0.000
M23.3 Other meniscus derangements
0.682 0.318 0.000
R12 Heartburn
0.681 0.319 0.000
D17 Benign lipomatous neoplasm
0.681 0.319 0.000
B15-B19 Viral hepatitis
0.680 0.320 0.000
M06 Other rheumatoid arthritis
0.680 0.320 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.679 0.320 0.000
Z91.7 Personal history of female genital mutilation
0.679 0.320 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.679 0.320 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.679 0.320 0.000
Z91.2 Personal history of poor personal hygiene
0.679 0.320 0.000
R15 Faecal incontinence
0.679 0.321 0.000
I42.2 Other hypertrophic cardiomyopathy
0.679 0.321 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.679 0.321 0.000
M17.9 Gonarthrosis, unspecified
0.679 0.321 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.678 0.322 0.000
C79.6 Secondary malignant neoplasm of ovary
0.678 0.322 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.678 0.322 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.678 0.322 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.678 0.322 0.000
C44.6 Skin of upper limb, including shoulder
0.678 0.322 0.000
R07.2 Precordial pain
0.678 0.322 0.000
M11 Other crystal arthropathies
0.678 0.322 0.000
D12.7 Rectosigmoid junction
0.678 0.322 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.676 0.324 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.676 0.324 0.000
Z97.4 Presence of external hearing-aid
0.676 0.324 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.676 0.324 0.000
N98 Complications associated with artificial fertilisation
0.676 0.324 0.000
N91 Absent, scanty and rare menstruation
0.676 0.324 0.000
N82 Fistulae involving female genital tract
0.676 0.324 0.000
N96 Habitual aborter
0.676 0.324 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.675 0.324 0.000
F70-F79 Mental retardation
0.675 0.324 0.000
F60-F69 Disorders of adult personality and behaviour
0.675 0.324 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.675 0.324 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.675 0.325 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.674 0.325 0.000
N15 Other renal tubulo-interstitial diseases
0.674 0.325 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.674 0.325 0.000
N11 Chronic tubulo-interstitial nephritis
0.674 0.325 0.000
N10 Acute tubulo-interstitial nephritis
0.674 0.325 0.000
N95.2 Postmenopausal atrophic vaginitis
0.674 0.325 0.000
I31 Other diseases of pericardium
0.674 0.325 0.000
M23.4 Loose body in knee
0.674 0.326 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.674 0.326 0.000
R35 Polyuria
0.672 0.328 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.672 0.328 0.000
C44.2 Skin of ear and external auricular canal
0.671 0.329 0.000
I50.1 Left ventricular failure
0.671 0.329 0.000
Z01.8 Other specified special examinations
0.669 0.331 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.669 0.331 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.668 0.332 0.000
L30.5 Pityriasis alba
0.668 0.332 0.000
L30.4 Erythema intertrigo
0.668 0.332 0.000
L30.3 Infective dermatitis
0.668 0.332 0.000
L30.2 Cutaneous autosensitisation
0.668 0.332 0.000
L30.1 Dyshidrosis [pompholyx]
0.668 0.332 0.000
L30.0 Nummular dermatitis
0.668 0.332 0.000
C44.4 Skin of scalp and neck
0.667 0.333 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.667 0.333 0.000
Z57 Occupational exposure to risk-factors
0.667 0.333 0.000
B99-B99 Other infectious diseases
0.666 0.333 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.666 0.333 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.666 0.333 0.000
B65-B83 Helminthiases
0.666 0.333 0.000
B50-B64 Protozoal diseases
0.666 0.333 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.666 0.333 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.666 0.333 0.000
A80-A89 Viral infections of the central nervous system
0.666 0.333 0.000
A75-A79 Rickettsioses
0.666 0.333 0.000
A70-A74 Other diseases caused by chlamydiae
0.666 0.333 0.000
A65-A69 Other spirochaetal diseases
0.666 0.333 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.666 0.333 0.000
A20-A28 Certain zoonotic bacterial diseases
0.666 0.333 0.000
A15-A19 Tuberculosis
0.666 0.333 0.000
I15 Secondary hypertension
0.666 0.334 0.000
I13 Hypertensive heart and renal disease
0.666 0.334 0.000
I11 Hypertensive heart disease
0.666 0.334 0.000
R17 Unspecified jaundice
0.666 0.334 0.000
Z74.0 Reduced mobility
0.665 0.335 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.664 0.336 0.000
D45 Polycythaemia vera
0.664 0.336 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.664 0.336 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.663 0.337 0.000
M10 Gout
0.663 0.337 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.663 0.337 0.000
M18 Arthrosis of first carpometacarpal joint
0.662 0.338 0.000
R60 Oedema, not elsewhere classified
0.662 0.338 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.662 0.338 0.000
Z09.4 Follow-up examination after treatment of fracture
0.662 0.338 0.000
Z09.3 Follow-up examination after psychotherapy
0.662 0.338 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.662 0.338 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.661 0.338 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.659 0.340 0.000
I50.9 Heart failure, unspecified
0.658 0.342 0.000
M47 Spondylosis
0.657 0.343 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.657 0.343 0.000
N95.3 States associated with artificial menopause
0.657 0.343 0.000
N95.1 Menopausal and female climacteric states
0.657 0.343 0.000
R53 Malaise and fatigue
0.657 0.343 0.000
J33 Nasal polyp
0.657 0.343 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.655 0.344 0.000
N94.5 Secondary dysmenorrhoea
0.655 0.344 0.000
N94.4 Primary dysmenorrhoea
0.655 0.344 0.000
N94.3 Premenstrual tension syndrome
0.655 0.344 0.000
N94.2 Vaginismus
0.655 0.344 0.000
N94.0 Mittelschmerz
0.655 0.344 0.000
N89.5 Stricture and atresia of vagina
0.655 0.345 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.654 0.346 0.000
M23.9 Internal derangement of knee, unspecified
0.653 0.347 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.653 0.347 0.000
M23.5 Chronic instability of knee
0.653 0.347 0.000
M23.1 Discoid meniscus (congenital)
0.653 0.347 0.000
M23.0 Cystic meniscus
0.653 0.347 0.000
C50-C50 Malignant neoplasm of breast
0.652 0.348 0.000
H80-H83 Diseases of inner ear
0.652 0.348 0.000
I49.9 Cardiac arrhythmia, unspecified
0.651 0.349 0.000
N13.8 Other obstructive and reflux uropathy
0.651 0.349 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.651 0.349 0.000
N13.6 Pyonephrosis
0.651 0.349 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.651 0.349 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.651 0.349 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.651 0.349 0.000
N70 Salpingitis and oophoritis
0.649 0.351 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.648 0.352 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.648 0.352 0.000
Z87.0 Personal history of diseases of the respiratory system
0.648 0.352 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.647 0.353 0.000
Q00-Q07 Congenital malformations of the nervous system
0.647 0.353 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.644 0.356 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.644 0.356 0.000
R19.4 Change in bowel habit
0.644 0.356 0.000
R06.0 Dyspnoea
0.643 0.357 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.643 0.357 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.643 0.357 0.000
R02 Gangrene, not elsewhere classified
0.642 0.358 0.000
F40 Phobic anxiety disorders
0.641 0.359 0.000
X60-X84 Intentional self-harm
0.641 0.359 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.641 0.359 0.000
Y35-Y36 Legal intervention and operations of war
0.641 0.359 0.000
Y10-Y34 Event of undetermined intent
0.641 0.359 0.000
Y00-Y09 Assault
0.641 0.359 0.000
X85-X99 Assault
0.641 0.359 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.641 0.359 0.000
X50-X57 Overexertion, travel and privation
0.641 0.359 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.641 0.359 0.000
X30-X39 Exposure to forces of nature
0.641 0.359 0.000
X20-X29 Contact with venomous animals and plants
0.641 0.359 0.000
X10-X19 Contact with heat and hot substances
0.641 0.359 0.000
X00-X09 Exposure to smoke, fire and flames
0.641 0.359 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.641 0.359 0.000
W75-W84 Other accidental threats to breathing
0.641 0.359 0.000
W65-W74 Accidental drowning and submersion
0.641 0.359 0.000
W50-W64 Exposure to animate mechanical forces
0.641 0.359 0.000
W20-W49 Exposure to inanimate mechanical forces
0.641 0.359 0.000
V98-V99 Other and unspecified transport accidents
0.641 0.359 0.000
V95-V97 Air and space transport accidents
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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