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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117733335
log Bayes Factor = 14.2344
Chromosome 11   position 6,473,013  (GRCh37) Explore rs117733335 on Ensembl!
Variant rs117733335 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
R50-R69 General symptoms and signs
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
Chapter XI Diseases of the digestive system
0.992 0.008 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
I60-I69 Cerebrovascular diseases
0.981 0.019 0.000
A00-A09 Intestinal infectious diseases
0.980 0.020 0.000
I30-I52 Other forms of heart disease
0.978 0.022 0.000
R56 Convulsions, not elsewhere classified
0.978 0.022 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.974 0.026 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.971 0.029 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.970 0.030 0.000
R56.8 Other and unspecified convulsions
0.964 0.036 0.000
K02 Dental caries
0.957 0.043 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.953 0.047 0.000
R51 Headache
0.952 0.048 0.000
K70-K77 Diseases of liver
0.950 0.050 0.000
E65-E68 Obesity and other hyperalimentation
0.948 0.052 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.947 0.053 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.941 0.059 0.000
E70-E90 Metabolic disorders
0.941 0.059 0.000
I51 Complications and ill-defined descriptions of heart disease
0.936 0.064 0.000
M15-M19 Arthrosis
0.934 0.066 0.000
K02.9 Dental caries, unspecified
0.933 0.067 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.929 0.071 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.928 0.072 0.000
B95-B98 Bacterial, viral and other infectious agents
0.927 0.073 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.926 0.074 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.921 0.079 0.000
I50 Heart failure
0.919 0.081 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.919 0.081 0.000
E50-E64 Other nutritional deficiencies
0.918 0.082 0.000
E66 Obesity
0.916 0.084 0.000
R55 Syncope and collapse
0.908 0.092 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.906 0.094 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.905 0.095 0.000
I51.7 Cardiomegaly
0.902 0.098 0.000
M18 Arthrosis of first carpometacarpal joint
0.900 0.100 0.000
E66.9 Obesity, unspecified
0.899 0.101 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.897 0.103 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.896 0.104 0.000
I67 Other cerebrovascular diseases
0.893 0.107 0.000
F17.1 Harmful use
0.892 0.108 0.000
G62 Other polyneuropathies
0.890 0.110 0.000
I42 Cardiomyopathy
0.889 0.111 0.000
G20-G26 Extrapyramidal and movement disorders
0.885 0.115 0.000
Chapter XX External causes of morbidity and mortality
0.883 0.117 0.000
K14 Diseases of tongue
0.880 0.120 0.000
K76 Other diseases of liver
0.876 0.124 0.000
M45-M49 Spondylopathies
0.876 0.124 0.000
E86 Volume depletion
0.874 0.126 0.000
F41 Other anxiety disorders
0.871 0.129 0.000
E53 Deficiency of other B group vitamins
0.870 0.130 0.000
Chapter X Diseases of the respiratory system
0.867 0.133 0.000
G40-G47 Episodic and paroxysmal disorders
0.866 0.134 0.000
R63 Symptoms and signs concerning food and fluid intake
0.864 0.136 0.000
I74 Arterial embolism and thrombosis
0.861 0.139 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.861 0.139 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.860 0.140 0.000
I73 Other peripheral vascular diseases
0.859 0.141 0.000
M80-M85 Disorders of bone density and structure
0.858 0.142 0.000
R94 Abnormal results of function studies
0.854 0.146 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.854 0.146 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.853 0.147 0.000
G90-G99 Other disorders of the nervous system
0.852 0.148 0.000
G62.9 Polyneuropathy, unspecified
0.851 0.149 0.000
K08 Other disorders of teeth and supporting structures
0.850 0.150 0.000
E83 Disorders of mineral metabolism
0.848 0.152 0.000
A04 Other bacterial intestinal infections
0.842 0.158 0.000
E53.8 Deficiency of other specified B group vitamins
0.836 0.164 0.000
K70 Alcoholic liver disease
0.831 0.169 0.000
M50-M54 Other dorsopathies
0.831 0.169 0.000
K13 Other diseases of lip and oral mucosa
0.830 0.170 0.000
F30-F39 Mood [affective] disorders
0.829 0.171 0.000
K12 Stomatitis and related lesions
0.829 0.171 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.828 0.172 0.000
I62 Other nontraumatic intracranial haemorrhage
0.828 0.172 0.000
K14.0 Glossitis
0.826 0.174 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.823 0.177 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.823 0.177 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.823 0.177 0.000
I50.1 Left ventricular failure
0.823 0.177 0.000
F99-F99 Unspecified mental disorder
0.822 0.178 0.000
K11 Diseases of salivary glands
0.820 0.180 0.000
K09 Cysts of oral region, not elsewhere classified
0.820 0.180 0.000
I50.0 Congestive heart failure
0.820 0.180 0.000
B65-B83 Helminthiases
0.817 0.183 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.816 0.184 0.000
T39.1 4-Aminophenol derivatives
0.815 0.185 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.814 0.186 0.000
Chapter VIII Diseases of the ear and mastoid process
0.814 0.186 0.000
A08 Viral and other specified intestinal infections
0.813 0.187 0.000
I95 Hypotension
0.812 0.188 0.000
I47 Paroxysmal tachycardia
0.806 0.194 0.000
I72 Other aneurysm
0.806 0.194 0.000
R20 Disturbances of skin sensation
0.805 0.195 0.000
B35-B49 Mycoses
0.802 0.198 0.000
J40-J47 Chronic lower respiratory diseases
0.800 0.200 0.000
I51.8 Other ill-defined heart diseases
0.800 0.200 0.000
S70-S79 Injuries to the hip and thigh
0.799 0.201 0.000
E20-E35 Disorders of other endocrine glands
0.799 0.201 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.799 0.201 0.000
J60-J70 Lung diseases due to external agents
0.792 0.208 0.000
M19 Other arthrosis
0.791 0.209 0.000
I67.9 Cerebrovascular disease, unspecified
0.791 0.209 0.000
R52 Pain, not elsewhere classified
0.789 0.211 0.000
R26 Abnormalities of gait and mobility
0.789 0.211 0.000
I61 Intracerebral haemorrhage
0.788 0.212 0.000
K50-K52 Noninfective enteritis and colitis
0.788 0.212 0.000
R54 Senility
0.786 0.214 0.000
G20 Parkinson's disease
0.784 0.216 0.000
K90-K93 Other diseases of the digestive system
0.783 0.217 0.000
K76.9 Liver disease, unspecified
0.782 0.218 0.000
T66-T78 Other and unspecified effects of external causes
0.782 0.218 0.000
R94.5 Abnormal results of liver function studies
0.778 0.222 0.000
R23 Other skin changes
0.778 0.222 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.776 0.223 0.000
Chapter VII Diseases of the eye and adnexa
0.776 0.224 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.775 0.225 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.775 0.225 0.000
R47-R49 Symptoms and signs involving speech and voice
0.774 0.226 0.000
M47 Spondylosis
0.773 0.227 0.000
F41.2 Mixed anxiety and depressive disorder
0.772 0.228 0.000
I42.8 Other cardiomyopathies
0.769 0.231 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.766 0.234 0.000
G70-G73 Diseases of myoneural junction and muscle
0.765 0.235 0.000
G30-G32 Other degenerative diseases of the nervous system
0.764 0.236 0.000
F40 Phobic anxiety disorders
0.762 0.238 0.000
S90-S99 Injuries to the ankle and foot
0.760 0.239 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.760 0.240 0.000
F10.2 Dependence syndrome
0.760 0.240 0.000
I73.9 Peripheral vascular disease, unspecified
0.760 0.240 0.000
I69 Sequelae of cerebrovascular disease
0.759 0.241 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.758 0.241 0.000
J44 Other chronic obstructive pulmonary disease
0.758 0.242 0.000
I34 Nonrheumatic mitral valve disorders
0.755 0.245 0.000
M16 Coxarthrosis [arthrosis of hip]
0.755 0.245 0.000
E83.5 Disorders of calcium metabolism
0.755 0.245 0.000
I78 Diseases of capillaries
0.754 0.246 0.000
R21 Rash and other nonspecific skin eruption
0.754 0.246 0.000
F80-F89 Disorders of psychological development
0.753 0.247 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.749 0.251 0.000
I46 Cardiac arrest
0.748 0.252 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.748 0.252 0.000
K76.6 Portal hypertension
0.747 0.253 0.000
E40-E46 Malnutrition
0.744 0.256 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.744 0.256 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.742 0.258 0.000
F10.3 Withdrawal state
0.740 0.260 0.000
I71 Aortic aneurysm and dissection
0.740 0.260 0.000
F42 Obsessive-compulsive disorder
0.740 0.260 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.740 0.260 0.000
K72 Hepatic failure, not elsewhere classified
0.739 0.260 0.000
M65-M68 Disorders of synovium and tendon
0.739 0.261 0.000
Y43 Primarily systemic agents
0.739 0.261 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.738 0.262 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.738 0.262 0.000
H65-H75 Diseases of middle ear and mastoid
0.738 0.262 0.000
I47.2 Ventricular tachycardia
0.736 0.264 0.000
R61 Hyperhidrosis
0.735 0.265 0.000
J40 Bronchitis, not specified as acute or chronic
0.735 0.265 0.000
M84 Disorders of continuity of bone
0.734 0.266 0.000
I30 Acute pericarditis
0.733 0.266 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.733 0.267 0.000
M86-M90 Other osteopathies
0.731 0.269 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.730 0.270 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.730 0.270 0.000
R57 Shock, not elsewhere classified
0.730 0.270 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.730 0.270 0.000
F00 Dementia in Alzheimer's disease
0.730 0.270 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.729 0.271 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.729 0.271 0.000
K65-K67 Diseases of peritoneum
0.728 0.272 0.000
M05-M14 Inflammatory polyarthropathies
0.728 0.272 0.000
S32 Fracture of lumbar spine and pelvis
0.727 0.273 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.726 0.274 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.726 0.274 0.000
R63.0 Anorexia
0.725 0.275 0.000
I05-I09 Chronic rheumatic heart diseases
0.725 0.275 0.000
I35 Nonrheumatic aortic valve disorders
0.724 0.276 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.724 0.276 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.724 0.276 0.000
M91-M94 Chondropathies
0.722 0.277 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.722 0.278 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.721 0.279 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.720 0.279 0.000
K07 Dentofacial anomalies [including malocclusion]
0.720 0.280 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.720 0.280 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.719 0.281 0.000
M48 Other spondylopathies
0.719 0.281 0.000
R30-R39 Symptoms and signs involving the urinary system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.716 0.284 0.000
I74.5 Embolism and thrombosis of iliac artery
0.716 0.284 0.000
R68 Other general symptoms and signs
0.714 0.285 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.714 0.285 0.000
R62 Lack of expected normal physiological development
0.714 0.285 0.000
R64 Cachexia
0.714 0.285 0.000
R58 Haemorrhage, not elsewhere classified
0.714 0.285 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
K12.1 Other forms of stomatitis
0.713 0.287 0.000
F41.1 Generalised anxiety disorder
0.713 0.287 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.712 0.288 0.000
I95.1 Orthostatic hypotension
0.711 0.289 0.000
I77 Other disorders of arteries and arterioles
0.711 0.289 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.711 0.289 0.000
K10 Other diseases of jaws
0.710 0.290 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.710 0.290 0.000
K03 Other diseases of hard tissues of teeth
0.710 0.290 0.000
K00 Disorders of tooth development and eruption
0.710 0.290 0.000
R20.2 Paraesthesia of skin
0.710 0.290 0.000
I42.0 Dilated cardiomyopathy
0.710 0.290 0.000
F03 Unspecified dementia
0.708 0.292 0.000
J69 Pneumonitis due to solids and liquids
0.706 0.294 0.000
K01 Embedded and impacted teeth
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
I67.1 Cerebral aneurysm, nonruptured
0.704 0.296 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.703 0.297 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.703 0.297 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.703 0.297 0.000
E83.4 Disorders of magnesium metabolism
0.703 0.297 0.000
G62.8 Other specified polyneuropathies
0.703 0.297 0.000
A07 Other protozoal intestinal diseases
0.703 0.297 0.000
A06 Amoebiasis
0.703 0.297 0.000
A05 Other bacterial foodborne intoxications
0.703 0.297 0.000
A03 Shigellosis
0.703 0.297 0.000
A02 Other Salmonella infections
0.703 0.297 0.000
A01 Typhoid and paratyphoid fevers
0.703 0.297 0.000
A00 Cholera
0.703 0.297 0.000
K08.3 Retained dental root
0.702 0.298 0.000
I52 Other heart disorders in diseases classified elsewhere
0.701 0.298 0.000
I48 Atrial fibrillation and flutter
0.701 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.701 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.701 0.298 0.000
I40 Acute myocarditis
0.701 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.701 0.298 0.000
I37 Pulmonary valve disorders
0.701 0.298 0.000
I36 Nonrheumatic tricuspid valve disorders
0.701 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.701 0.298 0.000
R52.2 Other chronic pain
0.701 0.299 0.000
R56.0 Febrile convulsions
0.701 0.299 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
I60 Subarachnoid haemorrhage
0.699 0.300 0.000
I70 Atherosclerosis
0.699 0.301 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.698 0.302 0.000
K11.5 Sialolithiasis
0.698 0.302 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.698 0.302 0.000
K09.0 Developmental odontogenic cysts
0.698 0.302 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.697 0.303 0.000
I63 Cerebral infarction
0.697 0.303 0.000
B15-B19 Viral hepatitis
0.697 0.303 0.000
T33-T35 Frostbite
0.696 0.304 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.696 0.304 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.696 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.304 0.000
T00-T07 Injuries involving multiple body regions
0.696 0.304 0.000
S10-S19 Injuries to the neck
0.696 0.304 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.696 0.304 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.695 0.304 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.695 0.304 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.695 0.304 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.695 0.304 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.695 0.304 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.695 0.304 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.695 0.304 0.000
F11 Mental and behavioural disorders due to use of opioids
0.695 0.304 0.000
F99 Mental disorder, not otherwise specified
0.695 0.305 0.000
S40-S49 Injuries to the shoulder and upper arm
0.695 0.305 0.000
J09-J18 Influenza and pneumonia
0.695 0.305 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.693 0.307 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.693 0.307 0.000
G25 Other extrapyramidal and movement disorders
0.693 0.307 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.693 0.307 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.693 0.307 0.000
M50 Cervical disk disorders
0.692 0.308 0.000
I42.2 Other hypertrophic cardiomyopathy
0.690 0.310 0.000
E88 Other metabolic disorders
0.689 0.310 0.000
F43 Reaction to severe stress, and adjustment disorders
0.689 0.310 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.689 0.311 0.000
B80 Enterobiasis
0.689 0.311 0.000
G95 Other diseases of spinal cord
0.689 0.311 0.000
T79-T79 Certain early complications of trauma
0.688 0.312 0.000
W20-W49 Exposure to inanimate mechanical forces
0.688 0.312 0.000
K86 Other diseases of pancreas
0.687 0.313 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.687 0.313 0.000
G44 Other headache syndromes
0.687 0.313 0.000
K02.8 Other dental caries
0.686 0.314 0.000
K02.5 Caries with pulp exposure
0.686 0.314 0.000
K02.4 Odontoclasia
0.686 0.314 0.000
K02.3 Arrested dental caries
0.686 0.314 0.000
K02.2 Caries of cementum
0.686 0.314 0.000
K02.1 Caries of dentin
0.686 0.314 0.000
K02.0 Caries limited to enamel
0.686 0.314 0.000
I67.8 Other specified cerebrovascular diseases
0.686 0.314 0.000
I72.4 Aneurysm of artery of lower extremity
0.686 0.314 0.000
M85 Other disorders of bone density and structure
0.685 0.315 0.000
J20-J22 Other acute lower respiratory infections
0.685 0.315 0.000
M54 Dorsalgia
0.684 0.316 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.683 0.316 0.000
Y43.3 Other antineoplastic drugs
0.683 0.317 0.000
F45 Somatoform disorders
0.683 0.317 0.000
L20-L30 Dermatitis and eczema
0.683 0.317 0.000
K77 Liver disorders in diseases classified elsewhere
0.681 0.319 0.000
K73 Chronic hepatitis, not elsewhere classified
0.681 0.319 0.000
K71 Toxic liver disease
0.681 0.319 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
E67 Other hyperalimentation
0.680 0.320 0.000
E68 Sequelae of hyperalimentation
0.680 0.320 0.000
E65 Localised adiposity
0.680 0.320 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.680 0.320 0.000
S20-S29 Injuries to the thorax
0.679 0.321 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.679 0.321 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.679 0.321 0.000
F48 Other neurotic disorders
0.679 0.321 0.000
F44 Dissociative [conversion] disorders
0.679 0.321 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.679 0.321 0.000
K70.0 Alcoholic fatty liver
0.676 0.324 0.000
I33 Acute and subacute endocarditis
0.676 0.324 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.675 0.325 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.675 0.325 0.000
E85 Amyloidosis
0.675 0.325 0.000
E84 Cystic fibrosis
0.675 0.325 0.000
E79 Disorders of purine and pyrimidine metabolism
0.675 0.325 0.000
E77 Disorders of glycoprotein metabolism
0.675 0.325 0.000
E76 Disorders of glycosaminoglycan metabolism
0.675 0.325 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.675 0.325 0.000
E74 Other disorders of carbohydrate metabolism
0.675 0.325 0.000
E73 Lactose intolerance
0.675 0.325 0.000
E72 Other disorders of amino-acid metabolism
0.675 0.325 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.675 0.325 0.000
E70 Disorders of aromatic amino-acid metabolism
0.675 0.325 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.675 0.325 0.000
S60-S69 Injuries to the wrist and hand
0.674 0.326 0.000
F41.9 Anxiety disorder, unspecified
0.673 0.327 0.000
E27 Other disorders of adrenal gland
0.673 0.327 0.000
G45.3 Amaurosis fugax
0.672 0.328 0.000
R53 Malaise and fatigue
0.672 0.328 0.000
M47.9 Spondylosis, unspecified
0.672 0.328 0.000
I51.6 Cardiovascular disease, unspecified
0.671 0.329 0.000
I51.5 Myocardial degeneration
0.671 0.329 0.000
I51.4 Myocarditis, unspecified
0.671 0.329 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.671 0.329 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.671 0.329 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.671 0.329 0.000
I51.0 Cardiac septal defect, acquired
0.671 0.329 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.671 0.329 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.671 0.329 0.000
K70.3 Alcoholic cirrhosis of liver
0.670 0.330 0.000
M40-M43 Deforming dorsopathies
0.670 0.330 0.000
M15 Polyarthrosis
0.670 0.330 0.000
K75 Other inflammatory liver diseases
0.669 0.331 0.000
R25 Abnormal involuntary movements
0.667 0.333 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.667 0.333 0.000
G61 Inflammatory polyneuropathy
0.666 0.334 0.000
G60 Hereditary and idiopathic neuropathy
0.666 0.334 0.000
G64 Other disorders of peripheral nervous system
0.666 0.334 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.665 0.335 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.665 0.335 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.665 0.335 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.665 0.335 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.665 0.335 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.665 0.335 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.665 0.335 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.665 0.335 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.665 0.335 0.000
T36 Poisoning by systemic antibiotics
0.665 0.335 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.665 0.335 0.000
R27 Other lack of coordination
0.665 0.335 0.000
B37 Candidiasis
0.663 0.337 0.000
I45 Other conduction disorders
0.662 0.338 0.000
Y40 Systemic antibiotics
0.662 0.338 0.000
F17.9 Unspecified mental and behavioural disorder
0.660 0.340 0.000
F17.8 Other mental and behavioural disorders
0.660 0.340 0.000
F17.7 Residual and late-onset psychotic disorder
0.660 0.340 0.000
F17.6 Amnesic syndrome
0.660 0.340 0.000
F17.5 Psychotic disorder
0.660 0.340 0.000
F17.4 Withdrawal state with delirium
0.660 0.340 0.000
F17.3 Withdrawal state
0.660 0.340 0.000
F17.0 Acute intoxication
0.660 0.340 0.000
H40-H42 Glaucoma
0.660 0.340 0.000
I73.0 Raynaud's syndrome
0.659 0.341 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.659 0.341 0.000
I99 Other and unspecified disorders of circulatory system
0.659 0.341 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.658 0.342 0.000
E63 Other nutritional deficiencies
0.658 0.342 0.000
E61 Deficiency of other nutrient elements
0.658 0.342 0.000
E56 Other vitamin deficiencies
0.658 0.342 0.000
E51 Thiamine deficiency
0.658 0.342 0.000
E50 Vitamin A deficiency
0.658 0.342 0.000
E60 Dietary zinc deficiency
0.658 0.342 0.000
E59 Dietary selenium deficiency
0.658 0.342 0.000
E58 Dietary calcium deficiency
0.658 0.342 0.000
E54 Ascorbic acid deficiency
0.658 0.342 0.000
E52 Niacin deficiency [pellagra]
0.658 0.342 0.000
F33 Recurrent depressive disorder
0.657 0.343 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.657 0.343 0.000
E66.1 Drug-induced obesity
0.657 0.343 0.000
E66.0 Obesity due to excess calories
0.657 0.343 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.656 0.344 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.655 0.345 0.000
B25-B34 Other viral diseases
0.655 0.345 0.000
S70 Superficial injury of hip and thigh
0.655 0.345 0.000
K92 Other diseases of digestive system
0.654 0.346 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.654 0.346 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.654 0.346 0.000
M19.0 Primary arthrosis of other joints
0.654 0.346 0.000
K05 Gingivitis and periodontal diseases
0.652 0.348 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.651 0.348 0.000
M16.0 Primary coxarthrosis, bilateral
0.651 0.349 0.000
R23.3 Spontaneous ecchymoses
0.651 0.349 0.000
I42.9 Cardiomyopathy, unspecified
0.650 0.350 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.650 0.350 0.000
F02 Dementia in other diseases classified elsewhere
0.650 0.350 0.000
F01 Vascular dementia
0.650 0.350 0.000
F09 Unspecified organic or symptomatic mental disorder
0.650 0.350 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.650 0.350 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.650 0.350 0.000
M47.2 Other spondylosis with radiculopathy
0.650 0.350 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.650 0.350 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.650 0.350 0.000
E83.3 Disorders of phosphorus metabolism
0.649 0.351 0.000
R47 Speech disturbances, not elsewhere classified
0.648 0.351 0.000
K74 Fibrosis and cirrhosis of liver
0.648 0.352 0.000
X60-X84 Intentional self-harm
0.647 0.353 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.646 0.354 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.645 0.354 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.645 0.354 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.645 0.354 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.645 0.354 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.645 0.355 0.000
J69.0 Pneumonitis due to food and vomit
0.644 0.356 0.000
A08.4 Viral intestinal infection, unspecified
0.643 0.357 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.643 0.357 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.643 0.357 0.000
T39.4 Antirheumatics, not elsewhere classified
0.643 0.357 0.000
T39.2 Pyrazolone derivatives
0.643 0.357 0.000
S50-S59 Injuries to the elbow and forearm
0.643 0.357 0.000
A04.8 Other specified bacterial intestinal infections
0.640 0.359 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.640 0.360 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.640 0.360 0.000
I67.5 Moyamoya disease
0.640 0.360 0.000
I67.4 Hypertensive encephalopathy
0.640 0.360 0.000
I67.3 Progressive vascular leukoencephalopathy
0.640 0.360 0.000
I67.2 Cerebral atherosclerosis
0.640 0.360 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.640 0.360 0.000
K70.9 Alcoholic liver disease, unspecified
0.640 0.360 0.000
M81 Osteoporosis without pathological fracture
0.640 0.360 0.000
I95.9 Hypotension, unspecified
0.640 0.360 0.000
G62.2 Polyneuropathy due to other toxic agents
0.638 0.362 0.000
G62.1 Alcoholic polyneuropathy
0.638 0.362 0.000
G62.0 Drug-induced polyneuropathy
0.638 0.362 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.637 0.363 0.000
I42.6 Alcoholic cardiomyopathy
0.637 0.363 0.000
I42.5 Other restrictive cardiomyopathy
0.637 0.363 0.000
I42.4 Endocardial fibroelastosis
0.637 0.363 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.637 0.363 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.637 0.363 0.000
Chapter XIV Diseases of the genitourinary system
0.637 0.363 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.636 0.363 0.000
I31 Other diseases of pericardium
0.636 0.364 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.635 0.365 0.000
G24 Dystonia
0.635 0.365 0.000
G23 Other degenerative diseases of basal ganglia
0.635 0.365 0.000
G21 Secondary Parkinsonism
0.635 0.365 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.635 0.365 0.000
G22 Parkinsonism in diseases classified elsewhere
0.635 0.365 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.634 0.365 0.000
F31 Bipolar affective disorder
0.634 0.366 0.000
H73 Other disorders of tympanic membrane
0.634 0.366 0.000
V10-V19 Pedal cyclist injured in transport accident
0.634 0.366 0.000
Y35-Y36 Legal intervention and operations of war
0.633 0.367 0.000
Y10-Y34 Event of undetermined intent
0.633 0.367 0.000
Y00-Y09 Assault
0.633 0.367 0.000
X85-X99 Assault
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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