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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117761474
log Bayes Factor = 15.8826
Chromosome 12   position 113,029,356  (GRCh37) Explore rs117761474 on Ensembl!
Variant rs117761474 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
H25-H28 Disorders of lens
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
H25 Senile cataract
0.998 0.002 0.000
M15-M19 Arthrosis
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
M19 Other arthrosis
0.990 0.010 0.000
M19.9 Arthrosis, unspecified
0.987 0.013 0.000
M50-M54 Other dorsopathies
0.987 0.013 0.000
G40-G47 Episodic and paroxysmal disorders
0.984 0.016 0.000
H26 Other cataract
0.983 0.017 0.000
H25.1 Senile nuclear cataract
0.982 0.018 0.000
M25 Other joint disorders, not elsewhere classified
0.982 0.018 0.000
M54 Dorsalgia
0.979 0.021 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.977 0.023 0.000
H25.0 Senile incipient cataract
0.975 0.025 0.000
H30-H36 Disorders of choroid and retina
0.973 0.027 0.000
M20 Acquired deformities of fingers and toes
0.972 0.028 0.000
M45-M49 Spondylopathies
0.964 0.036 0.000
B95-B98 Bacterial, viral and other infectious agents
0.963 0.037 0.000
M25.5 Pain in joint
0.960 0.040 0.000
H26.9 Cataract, unspecified
0.953 0.047 0.000
Chapter IX Diseases of the circulatory system
0.952 0.048 0.000
M54.5 Low back pain
0.946 0.054 0.000
G81 Hemiplegia
0.945 0.055 0.000
M47 Spondylosis
0.943 0.057 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.940 0.060 0.000
H33 Retinal detachments and breaks
0.939 0.061 0.000
I60-I69 Cerebrovascular diseases
0.939 0.061 0.000
M25.57 Pain in joint (Ankle and foot)
0.939 0.061 0.000
G40 Epilepsy
0.934 0.066 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.929 0.071 0.000
Chapter XI Diseases of the digestive system
0.928 0.072 0.000
M47.8 Other spondylosis
0.924 0.076 0.000
G81.9 Hemiplegia, unspecified
0.923 0.077 0.000
H43-H45 Disorders of vitreous body and globe
0.907 0.093 0.000
M20.1 Hallux valgus (acquired)
0.907 0.093 0.000
M21 Other acquired deformities of limbs
0.901 0.099 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.900 0.100 0.000
H40-H42 Glaucoma
0.899 0.101 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.898 0.102 0.000
M54.3 Sciatica
0.896 0.104 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.895 0.105 0.000
G47 Sleep disorders
0.894 0.106 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.892 0.108 0.000
M54.59 Low back pain (Site unspecified)
0.891 0.109 0.000
A30-A49 Other bacterial diseases
0.891 0.109 0.000
H33.3 Retinal breaks without detachment
0.890 0.110 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.885 0.115 0.000
K70-K77 Diseases of liver
0.885 0.115 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.885 0.115 0.000
M18 Arthrosis of first carpometacarpal joint
0.885 0.115 0.000
I69 Sequelae of cerebrovascular disease
0.884 0.116 0.000
Chapter VIII Diseases of the ear and mastoid process
0.883 0.117 0.000
S00-S09 Injuries to the head
0.882 0.118 0.000
M80-M85 Disorders of bone density and structure
0.881 0.119 0.000
G40.9 Epilepsy, unspecified
0.879 0.121 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.874 0.126 0.000
M47.86 Other spondylosis (Lumbar region)
0.874 0.126 0.000
I67 Other cerebrovascular diseases
0.862 0.138 0.000
G90-G99 Other disorders of the nervous system
0.860 0.140 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.860 0.140 0.000
M54.9 Dorsalgia, unspecified
0.860 0.140 0.000
M24 Other specific joint derangements
0.848 0.152 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.847 0.153 0.000
H26.4 After-cataract
0.846 0.154 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.844 0.156 0.000
Chapter XX External causes of morbidity and mortality
0.844 0.156 0.000
H25.8 Other senile cataract
0.840 0.160 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.839 0.161 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.837 0.163 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.831 0.169 0.000
H53-H54 Visual disturbances and blindness
0.831 0.169 0.000
K65-K67 Diseases of peritoneum
0.827 0.173 0.000
H40 Glaucoma
0.826 0.174 0.000
B35-B49 Mycoses
0.825 0.175 0.000
G47.3 Sleep apnoea
0.825 0.175 0.000
B25-B34 Other viral diseases
0.824 0.176 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.824 0.176 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.821 0.179 0.000
M05-M14 Inflammatory polyarthropathies
0.821 0.179 0.000
M25.7 Osteophyte
0.819 0.180 0.000
I67.9 Cerebrovascular disease, unspecified
0.817 0.183 0.000
H43 Disorders of vitreous body
0.815 0.185 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.814 0.186 0.000
M80 Osteoporosis with pathological fracture
0.814 0.186 0.000
M54.50 Low back pain (Multiple sites in spine)
0.812 0.188 0.000
K70 Alcoholic liver disease
0.809 0.191 0.000
K02 Dental caries
0.808 0.192 0.000
M20.4 Other hammer toe(s) (acquired)
0.808 0.192 0.000
H04 Disorders of lachrymal system
0.806 0.194 0.000
M25.50 Pain in joint (Multiple sites)
0.805 0.194 0.000
G30-G32 Other degenerative diseases of the nervous system
0.805 0.195 0.000
M20.2 Hallux rigidus
0.805 0.195 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.804 0.196 0.000
Chapter XXII Codes for special purposes
0.803 0.197 0.000
M19.94 Arthrosis, unspecified (Hand)
0.802 0.198 0.000
G83 Other paralytic syndromes
0.801 0.199 0.000
H33.0 Retinal detachment with retinal break
0.793 0.207 0.000
L03 Cellulitis
0.793 0.207 0.000
K50-K52 Noninfective enteritis and colitis
0.790 0.210 0.000
M54.36 Sciatica (Lumbar region)
0.789 0.211 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.784 0.216 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.782 0.218 0.000
H26.2 Complicated cataract
0.782 0.218 0.000
A41 Other septicaemia
0.781 0.219 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.780 0.220 0.000
S00 Superficial injury of head
0.780 0.220 0.000
S01 Open wound of head
0.779 0.221 0.000
I60 Subarachnoid haemorrhage
0.778 0.222 0.000
H36 Retinal disorders in diseases classified elsewhere
0.775 0.225 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.774 0.226 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.774 0.226 0.000
M31 Other necrotising vasculopathies
0.774 0.226 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.774 0.226 0.000
Chapter V Mental and behavioural disorders
0.772 0.228 0.000
S90-S99 Injuries to the ankle and foot
0.770 0.230 0.000
M21.0 Valgus deformity, not elsewhere classified
0.767 0.233 0.000
I83 Varicose veins of lower extremities
0.767 0.233 0.000
H80-H83 Diseases of inner ear
0.765 0.235 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.764 0.236 0.000
M40-M43 Deforming dorsopathies
0.764 0.236 0.000
H10-H13 Disorders of conjunctiva
0.761 0.239 0.000
K35-K38 Diseases of appendix
0.758 0.242 0.000
M25.8 Other specified joint disorders
0.758 0.242 0.000
M19.1 Posttraumatic arthrosis of other joints
0.757 0.243 0.000
M20.5 Other deformities of toe(s) (acquired)
0.754 0.246 0.000
S20-S29 Injuries to the thorax
0.753 0.247 0.000
K02.9 Dental caries, unspecified
0.753 0.247 0.000
M54.39 Sciatica (Site unspecified)
0.753 0.247 0.000
G80 Infantile cerebral palsy
0.752 0.248 0.000
M19.0 Primary arthrosis of other joints
0.749 0.251 0.000
H40.9 Glaucoma, unspecified
0.749 0.251 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.748 0.252 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.748 0.252 0.000
K66 Other disorders of peritoneum
0.748 0.252 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.745 0.255 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.745 0.255 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.742 0.258 0.000
M46 Other inflammatory spondylopathies
0.742 0.258 0.000
H01 Other inflammation of eyelid
0.742 0.258 0.000
K04 Diseases of pulp and periapical tissues
0.740 0.260 0.000
K13 Other diseases of lip and oral mucosa
0.738 0.262 0.000
M54.57 Low back pain (Lumbosacral region)
0.738 0.262 0.000
K76 Other diseases of liver
0.738 0.262 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.738 0.262 0.000
H34 Retinal vascular occlusions
0.737 0.262 0.000
M21.3 Wrist or foot drop (acquired)
0.737 0.263 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.734 0.266 0.000
M47.82 Other spondylosis (Cervical region)
0.734 0.266 0.000
S02 Fracture of skull and facial bones
0.733 0.267 0.000
M47.2 Other spondylosis with radiculopathy
0.732 0.268 0.000
K50 Crohn's disease [regional enteritis]
0.731 0.269 0.000
H55-H59 Other disorders of eye and adnexa
0.730 0.270 0.000
M06 Other rheumatoid arthritis
0.728 0.272 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.727 0.273 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.725 0.275 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.725 0.275 0.000
A49 Bacterial infection of unspecified site
0.724 0.276 0.000
L50-L54 Urticaria and erythema
0.723 0.277 0.000
H44 Disorders of globe
0.723 0.277 0.000
S70-S79 Injuries to the hip and thigh
0.722 0.278 0.000
M35 Other systemic involvement of connective tissue
0.721 0.279 0.000
A00-A09 Intestinal infectious diseases
0.719 0.281 0.000
H35 Other retinal disorders
0.719 0.281 0.000
M25.54 Pain in joint (Hand)
0.718 0.282 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.717 0.283 0.000
H27 Other disorders of lens
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.716 0.284 0.000
H25.2 Senile cataract, morgagnian type
0.716 0.284 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.716 0.284 0.000
T66-T78 Other and unspecified effects of external causes
0.715 0.285 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.715 0.285 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.715 0.285 0.000
M54.4 Lumbago with sciatica
0.714 0.286 0.000
M65-M68 Disorders of synovium and tendon
0.714 0.286 0.000
M15 Polyarthrosis
0.712 0.288 0.000
M45 Ankylosing spondylitis
0.712 0.288 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A80-A89 Viral infections of the central nervous system
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.711 0.289 0.000
H04.1 Other disorders of lachrymal gland
0.711 0.289 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.710 0.290 0.000
M19.8 Other specified arthrosis
0.710 0.290 0.000
M19.2 Other secondary arthrosis
0.710 0.290 0.000
K70.3 Alcoholic cirrhosis of liver
0.709 0.291 0.000
M19.98 Arthrosis, unspecified (Other)
0.708 0.292 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.708 0.292 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.708 0.292 0.000
M53 Other dorsopathies, not elsewhere classified
0.707 0.293 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.707 0.293 0.000
W00-W19 Falls
0.707 0.293 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.705 0.294 0.000
G41 Status epilepticus
0.705 0.294 0.000
H26.3 Drug-induced cataract
0.705 0.295 0.000
H26.1 Traumatic cataract
0.705 0.295 0.000
H26.0 Infantile, juvenile and presenile cataract
0.705 0.295 0.000
M25.9 Joint disorder, unspecified
0.704 0.296 0.000
M25.3 Other instability of joint
0.704 0.296 0.000
M25.2 Flail joint
0.704 0.296 0.000
M25.1 Fistula of joint
0.704 0.296 0.000
M25.0 Haemarthrosis
0.704 0.296 0.000
B37 Candidiasis
0.704 0.296 0.000
B34 Viral infection of unspecified site
0.703 0.297 0.000
H33.2 Serous retinal detachment
0.703 0.297 0.000
G44 Other headache syndromes
0.702 0.298 0.000
M25.74 Osteophyte (Hand)
0.702 0.298 0.000
M54.8 Other dorsalgia
0.702 0.298 0.000
M54.6 Pain in thoracic spine
0.702 0.298 0.000
M54.0 Panniculitis affecting regions of neck and back
0.702 0.298 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.702 0.298 0.000
M25.56 Pain in joint (Lower leg)
0.701 0.299 0.000
G91 Hydrocephalus
0.701 0.299 0.000
I80 Phlebitis and thrombophlebitis
0.701 0.299 0.000
G93 Other disorders of brain
0.700 0.299 0.000
G82 Paraplegia and tetraplegia
0.700 0.300 0.000
M51 Other intervertebral disk disorders
0.700 0.300 0.000
I61 Intracerebral haemorrhage
0.700 0.300 0.000
G62 Other polyneuropathies
0.700 0.300 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.699 0.301 0.000
H05 Disorders of orbit
0.699 0.301 0.000
H43.1 Vitreous haemorrhage
0.698 0.302 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.698 0.302 0.000
H31 Other disorders of choroid
0.698 0.302 0.000
H30 Chorioretinal inflammation
0.698 0.302 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.698 0.302 0.000
S00.8 Superficial injury of other parts of head
0.697 0.303 0.000
M20.3 Other deformity of hallux (acquired)
0.697 0.303 0.000
M20.0 Deformity of finger(s)
0.697 0.303 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.694 0.306 0.000
H43.8 Other disorders of vitreous body
0.693 0.307 0.000
M86-M90 Other osteopathies
0.693 0.307 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.693 0.307 0.000
I05-I09 Chronic rheumatic heart diseases
0.693 0.307 0.000
S01.0 Open wound of scalp
0.693 0.307 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.693 0.307 0.000
M47.89 Other spondylosis (Site unspecified)
0.692 0.307 0.000
M49 Spondylopathies in diseases classified elsewhere
0.691 0.309 0.000
M54.1 Radiculopathy
0.691 0.309 0.000
M21.1 Varus deformity, not elsewhere classified
0.690 0.310 0.000
H53 Visual disturbances
0.690 0.310 0.000
D50-D53 Nutritional anaemias
0.689 0.311 0.000
M22 Disorders of patella
0.689 0.311 0.000
D70 Agranulocytosis
0.689 0.311 0.000
M25.59 Pain in joint (Site unspecified)
0.688 0.312 0.000
M25.58 Pain in joint (Other)
0.688 0.312 0.000
M25.52 Pain in joint (Upper arm)
0.688 0.312 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.688 0.312 0.000
T79-T79 Certain early complications of trauma
0.687 0.313 0.000
K70.9 Alcoholic liver disease, unspecified
0.685 0.315 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.684 0.316 0.000
L03.1 Cellulitis of other parts of limb
0.684 0.316 0.000
I00-I02 Acute rheumatic fever
0.683 0.317 0.000
I85 Oesophageal varices
0.683 0.317 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.682 0.317 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.682 0.317 0.000
H26.8 Other specified cataract
0.682 0.318 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.682 0.318 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.680 0.319 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.679 0.321 0.000
H40.0 Glaucoma suspect
0.679 0.321 0.000
H60-H62 Diseases of external ear
0.679 0.321 0.000
M54.55 Low back pain (Thoracolumbar region)
0.678 0.321 0.000
M54.54 Low back pain-Thoracic
0.678 0.321 0.000
M54.53 Low back pain-Cervicothoracic
0.678 0.321 0.000
M54.52 Low back pain-Cervical
0.678 0.321 0.000
M54.51 Low back pain-Occipit-atl-axl
0.678 0.321 0.000
K75 Other inflammatory liver diseases
0.678 0.322 0.000
G81.1 Spastic hemiplegia
0.678 0.322 0.000
G81.0 Flaccid hemiplegia
0.678 0.322 0.000
M47.1 Other spondylosis with myelopathy
0.676 0.324 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.676 0.324 0.000
G83.9 Paralytic syndrome, unspecified
0.676 0.324 0.000
T33-T35 Frostbite
0.674 0.326 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.674 0.326 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.674 0.326 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.674 0.326 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.674 0.326 0.000
T00-T07 Injuries involving multiple body regions
0.674 0.326 0.000
S10-S19 Injuries to the neck
0.674 0.326 0.000
H33.5 Other retinal detachments
0.673 0.326 0.000
H33.4 Traction detachment of retina
0.673 0.326 0.000
H33.1 Retinoschisis and retinal cysts
0.673 0.326 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.673 0.327 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.673 0.327 0.000
I62 Other nontraumatic intracranial haemorrhage
0.673 0.327 0.000
H65-H75 Diseases of middle ear and mastoid
0.672 0.328 0.000
I63 Cerebral infarction
0.672 0.328 0.000
M24.2 Disorder of ligament
0.671 0.328 0.000
K74 Fibrosis and cirrhosis of liver
0.671 0.329 0.000
S80-S89 Injuries to the knee and lower leg
0.669 0.330 0.000
G40.8 Other epilepsy
0.669 0.331 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.669 0.331 0.000
G40.5 Special epileptic syndromes
0.669 0.331 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.669 0.331 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.669 0.331 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.669 0.331 0.000
W20-W49 Exposure to inanimate mechanical forces
0.668 0.332 0.000
M47.9 Spondylosis, unspecified
0.667 0.333 0.000
K12 Stomatitis and related lesions
0.666 0.334 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.665 0.335 0.000
L03.3 Cellulitis of trunk
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.664 0.336 0.000
K66.0 Peritoneal adhesions
0.663 0.337 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.663 0.337 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.662 0.337 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.662 0.337 0.000
M47.84 Other spondylosis (Thoracic region)
0.662 0.337 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.662 0.337 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.662 0.337 0.000
M24.0 Loose body in joint
0.662 0.338 0.000
M84 Disorders of continuity of bone
0.660 0.339 0.000
M25.53 Pain in joint (Forearm)
0.660 0.340 0.000
L03.9 Cellulitis, unspecified
0.659 0.340 0.000
I67.2 Cerebral atherosclerosis
0.659 0.341 0.000
G47.9 Sleep disorder, unspecified
0.656 0.344 0.000
L05 Pilonidal cyst
0.656 0.344 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.655 0.345 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.654 0.346 0.000
K35 Acute appendicitis
0.654 0.346 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.653 0.347 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.652 0.348 0.000
M54.56 Low back pain (Lumbar region)
0.652 0.348 0.000
K05 Gingivitis and periodontal diseases
0.651 0.349 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.651 0.349 0.000
K10 Other diseases of jaws
0.650 0.350 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.649 0.350 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.649 0.351 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.647 0.353 0.000
K50.9 Crohn's disease, unspecified
0.647 0.353 0.000
H01.0 Blepharitis
0.647 0.353 0.000
K13.0 Diseases of lips
0.646 0.354 0.000
I67.1 Cerebral aneurysm, nonruptured
0.646 0.354 0.000
M21.9 Acquired deformity of limb, unspecified
0.646 0.354 0.000
M21.8 Other specified acquired deformities of limbs
0.646 0.354 0.000
M21.7 Unequal limb length (acquired)
0.646 0.354 0.000
M21.6 Other acquired deformities of ankle and foot
0.646 0.354 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.646 0.354 0.000
M21.4 Flat foot [pes planus] (acquired)
0.646 0.354 0.000
M21.2 Flexion deformity
0.646 0.354 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.645 0.355 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.645 0.355 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.645 0.355 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.645 0.355 0.000
G95 Other diseases of spinal cord
0.645 0.355 0.000
V20-V29 Motorcycle rider injured in transport accident
0.644 0.355 0.000
H42 Glaucoma in diseases classified elsewhere
0.644 0.356 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.644 0.356 0.000
M54.2 Cervicalgia
0.643 0.356 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.644 0.356 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.643 0.357 0.000
G20-G26 Extrapyramidal and movement disorders
0.643 0.357 0.000
S50-S59 Injuries to the elbow and forearm
0.642 0.358 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.642 0.358 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.642 0.358 0.000
M54.37 Sciatica (Lumbosacral region)
0.642 0.358 0.000
M54.35 Sciatica (Thoracolumbar region)
0.642 0.358 0.000
M54.34 Sciatica-Thoracic
0.642 0.358 0.000
M54.33 Sciatica-Cervicothoracic
0.642 0.358 0.000
M54.32 Sciatica-Cervical
0.642 0.358 0.000
M54.31 Sciatica-Occipit-atl-axl
0.642 0.358 0.000
M54.30 Sciatica (Multiple sites in spine)
0.642 0.358 0.000
L10-L14 Bullous disorders
0.642 0.358 0.000
M25.78 Osteophyte (Other)
0.642 0.358 0.000
R50-R69 General symptoms and signs
0.641 0.359 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.641 0.359 0.000
G47.8 Other sleep disorders
0.641 0.359 0.000
G47.4 Narcolepsy and cataplexy
0.641 0.359 0.000
G47.2 Disorders of the sleep-wake schedule
0.641 0.359 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.641 0.359 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.641 0.359 0.000
K72 Hepatic failure, not elsewhere classified
0.640 0.359 0.000
S01.4 Open wound of cheek and temporomandibular area
0.640 0.360 0.000
S40-S49 Injuries to the shoulder and upper arm
0.639 0.361 0.000
G96 Other disorders of central nervous system
0.639 0.361 0.000
A48 Other bacterial diseases, not elsewhere classified
0.639 0.361 0.000
A44 Bartonellosis
0.639 0.361 0.000
A43 Nocardiosis
0.639 0.361 0.000
A42 Actinomycosis
0.639 0.361 0.000
A40 Streptococcal septicaemia
0.639 0.361 0.000
A39 Meningococcal infection
0.639 0.361 0.000
A37 Whooping cough
0.639 0.361 0.000
A36 Diphtheria
0.639 0.361 0.000
A32 Listeriosis
0.639 0.361 0.000
A31 Infection due to other mycobacteria
0.639 0.361 0.000
A30 Leprosy [Hansen's disease]
0.639 0.361 0.000
A46 Erysipelas
0.639 0.361 0.000
A38 Scarlet fever
0.639 0.361 0.000
A35 Other tetanus
0.639 0.361 0.000
A34 Obstetrical tetanus
0.639 0.361 0.000
A33 Tetanus neonatorum
0.639 0.361 0.000
V80-V89 Other land transport accidents
0.639 0.361 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.639 0.361 0.000
H18 Other disorders of cornea
0.638 0.362 0.000
E50-E64 Other nutritional deficiencies
0.636 0.364 0.000
H52 Disorders of refraction and accommodation
0.636 0.364 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.636 0.364 0.000
K04.7 Periapical abscess without sinus
0.636 0.364 0.000
H81 Disorders of vestibular function
0.635 0.365 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.635 0.365 0.000
M06.9 Rheumatoid arthritis, unspecified
0.635 0.365 0.000
H53.9 Visual disturbance, unspecified
0.635 0.365 0.000
K09 Cysts of oral region, not elsewhere classified
0.635 0.365 0.000
K03 Other diseases of hard tissues of teeth
0.635 0.365 0.000
K00 Disorders of tooth development and eruption
0.635 0.365 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.635 0.365 0.000
K77 Liver disorders in diseases classified elsewhere
0.635 0.365 0.000
K73 Chronic hepatitis, not elsewhere classified
0.635 0.365 0.000
K71 Toxic liver disease
0.635 0.365 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.635 0.365 0.000
G45.4 Transient global amnesia
0.635 0.365 0.000
G45.3 Amaurosis fugax
0.635 0.365 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.635 0.365 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.635 0.365 0.000
G45.0 Vertebro-basilar artery syndrome
0.635 0.365 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.634 0.366 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.634 0.366 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.634 0.366 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.634 0.366 0.000
K01 Embedded and impacted teeth
0.634 0.366 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.634 0.366 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.634 0.366 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.634 0.366 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.634 0.366 0.000
H36.0 Diabetic retinopathy
0.634 0.366 0.000
M85 Other disorders of bone density and structure
0.632 0.367 0.000
S08 Traumatic amputation of part of head
0.632 0.368 0.000
S07 Crushing injury of head
0.632 0.368 0.000
S05 Injury of eye and orbit
0.632 0.368 0.000
S04 Injury of cranial nerves
0.632 0.368 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.632 0.368 0.000
M83 Adult osteomalacia
0.632 0.368 0.000
M82 Osteoporosis in diseases classified elsewhere
0.632 0.368 0.000
G61 Inflammatory polyneuropathy
0.631 0.368 0.000
I26 Pulmonary embolism
0.630 0.370 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.630 0.370 0.000
H54 Blindness and low vision
0.630 0.370 0.000
M16 Coxarthrosis [arthrosis of hip]
0.627 0.373 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.627 0.373 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.627 0.373 0.000
M50 Cervical disk disorders
0.626 0.374 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.626 0.374 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.625 0.374 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.625 0.374 0.000
H90-H95 Other disorders of ear
0.625 0.375 0.000
K90-K93 Other diseases of the digestive system
0.625 0.375 0.000
S32 Fracture of lumbar spine and pelvis
0.625 0.375 0.000
I86 Varicose veins of other sites
0.624 0.375 0.000
M24.1 Other articular cartilage disorders
0.623 0.377 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.623 0.377 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.623 0.377 0.000
R60 Oedema, not elsewhere classified
0.622 0.377 0.000
L08 Other local infections of skin and subcutaneous tissue
0.622 0.378 0.000
S06 Intracranial injury
0.622 0.378 0.000
M25.71 Osteophyte (Shoulder region)
0.622 0.378 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.620 0.380 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.620 0.380 0.000
H25.9 Senile cataract, unspecified
0.618 0.381 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.618 0.382 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.618 0.382 0.000
I67.5 Moyamoya disease
0.618 0.382 0.000
I67.4 Hypertensive encephalopathy
0.618 0.382 0.000
I67.3 Progressive vascular leukoencephalopathy
0.618 0.382 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.618 0.382 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.618 0.382 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.617 0.383 0.000
H21 Other disorders of iris and ciliary body
0.617 0.383 0.000
L03.8 Cellulitis of other sites
0.617 0.383 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.617 0.383 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.617 0.383 0.000
G90 Disorders of autonomic nervous system
0.617 0.383 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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