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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117850870
log Bayes Factor = 0.254485
Chromosome 10   position 50,523,748  (GRCh37) Explore rs117850870 on Ensembl!
Variant rs117850870 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E87 Other disorders of fluid, electrolyte and acid-base balance
0.454 0.546 0.000
E70-E90 Metabolic disorders
0.453 0.547 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.436 0.564 0.000
E87.2 Acidosis
0.430 0.570 0.000
E83 Disorders of mineral metabolism
0.419 0.581 0.000
E87.5 Hyperkalaemia
0.396 0.604 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.392 0.608 0.000
E88 Other metabolic disorders
0.384 0.616 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.377 0.623 0.000
E86 Volume depletion
0.374 0.626 0.000
Chapter VI Diseases of the nervous system
0.362 0.638 0.000
E83.5 Disorders of calcium metabolism
0.362 0.638 0.000
# Top node
0.360 0.640 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.359 0.641 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.354 0.646 0.000
G40-G47 Episodic and paroxysmal disorders
0.352 0.648 0.000
E87.0 Hyperosmolality and hypernatraemia
0.352 0.648 0.000
E73 Lactose intolerance
0.351 0.649 0.000
Chapter XX External causes of morbidity and mortality
0.350 0.650 0.000
E78.5 Hyperlipidaemia, unspecified
0.350 0.650 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.349 0.651 0.000
E83.1 Disorders of iron metabolism
0.346 0.654 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.346 0.654 0.000
M20-M25 Other joint disorders
0.344 0.656 0.000
M86-M90 Other osteopathies
0.339 0.661 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.336 0.664 0.000
E87.7 Fluid overload
0.334 0.665 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.334 0.666 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.328 0.672 0.000
E83.4 Disorders of magnesium metabolism
0.326 0.674 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.326 0.674 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.325 0.675 0.000
E87.4 Mixed disorder of acid-base balance
0.325 0.675 0.000
E85 Amyloidosis
0.325 0.675 0.000
E84 Cystic fibrosis
0.325 0.675 0.000
E79 Disorders of purine and pyrimidine metabolism
0.325 0.675 0.000
E77 Disorders of glycoprotein metabolism
0.325 0.675 0.000
E76 Disorders of glycosaminoglycan metabolism
0.325 0.675 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.325 0.675 0.000
E74 Other disorders of carbohydrate metabolism
0.325 0.675 0.000
E72 Other disorders of amino-acid metabolism
0.325 0.675 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.325 0.675 0.000
E70 Disorders of aromatic amino-acid metabolism
0.325 0.675 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.325 0.675 0.000
Y43 Primarily systemic agents
0.324 0.676 0.000
G63.2 Diabetic polyneuropathy
0.324 0.676 0.000
Chapter V Mental and behavioural disorders
0.322 0.678 0.000
M05-M14 Inflammatory polyarthropathies
0.320 0.680 0.000
M80-M85 Disorders of bone density and structure
0.318 0.682 0.000
E78.1 Pure hyperglyceridaemia
0.317 0.683 0.000
E20-E35 Disorders of other endocrine glands
0.317 0.683 0.000
E83.3 Disorders of phosphorus metabolism
0.316 0.684 0.000
M24 Other specific joint derangements
0.315 0.685 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.314 0.686 0.000
G40 Epilepsy
0.313 0.687 0.000
G30-G32 Other degenerative diseases of the nervous system
0.306 0.694 0.000
E40-E46 Malnutrition
0.305 0.695 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.305 0.695 0.000
G45.4 Transient global amnesia
0.304 0.696 0.000
G61 Inflammatory polyneuropathy
0.304 0.696 0.000
M20 Acquired deformities of fingers and toes
0.302 0.698 0.000
Y44 Agents primarily affecting blood constituents
0.301 0.699 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.301 0.699 0.000
E83.8 Other disorders of mineral metabolism
0.301 0.699 0.000
E83.2 Disorders of zinc metabolism
0.301 0.699 0.000
E83.0 Disorders of copper metabolism
0.301 0.699 0.000
E78.2 Mixed hyperlipidaemia
0.300 0.700 0.000
G70-G73 Diseases of myoneural junction and muscle
0.300 0.700 0.000
Y43.3 Other antineoplastic drugs
0.299 0.701 0.000
X50-X57 Overexertion, travel and privation
0.297 0.703 0.000
M23 Internal derangement of knee
0.293 0.707 0.000
E87.3 Alkalosis
0.291 0.709 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.290 0.710 0.000
M86 Osteomyelitis
0.290 0.710 0.000
M60-M63 Disorders of muscles
0.288 0.712 0.000
M89 Other disorders of bone
0.285 0.715 0.000
G60 Hereditary and idiopathic neuropathy
0.285 0.715 0.000
M13 Other arthritis
0.284 0.716 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.283 0.717 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.283 0.717 0.000
G47 Sleep disorders
0.283 0.717 0.000
M22 Disorders of patella
0.281 0.719 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.280 0.720 0.000
M65-M68 Disorders of synovium and tendon
0.278 0.722 0.000
E73.9 Lactose intolerance, unspecified
0.278 0.722 0.000
Y45.0 Opioids and related analgesics
0.276 0.724 0.000
E88.9 Metabolic disorder, unspecified
0.275 0.725 0.000
E88.8 Other specified metabolic disorders
0.275 0.725 0.000
E88.3 Tumour lysis syndrome
0.275 0.725 0.000
E88.2 Lipomatosis, not elsewhere classified
0.275 0.725 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.275 0.725 0.000
E23 Hypofunction and other disorders of pituitary gland
0.275 0.725 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.274 0.726 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.274 0.726 0.000
M00-M03 Infectious arthropathies
0.273 0.727 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.273 0.727 0.000
G44 Other headache syndromes
0.272 0.728 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.272 0.728 0.000
E78.8 Other disorders of lipoprotein metabolism
0.271 0.729 0.000
E78.6 Lipoprotein deficiency
0.271 0.729 0.000
E78.4 Other hyperlipidaemia
0.271 0.729 0.000
E78.3 Hyperchylomicronaemia
0.271 0.729 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.270 0.730 0.000
X60-X84 Intentional self-harm
0.270 0.730 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.270 0.730 0.000
E80.4 Gilbert's syndrome
0.269 0.731 0.000
M90 Osteopathies in diseases classified elsewhere
0.269 0.731 0.000
M81 Osteoporosis without pathological fracture
0.268 0.732 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.268 0.732 0.000
M20.5 Other deformities of toe(s) (acquired)
0.268 0.732 0.000
S10-S19 Injuries to the neck
0.268 0.732 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.267 0.733 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.267 0.733 0.000
G61.8 Other inflammatory polyneuropathies
0.266 0.734 0.000
Y44.2 Anticoagulants
0.266 0.734 0.000
E50-E64 Other nutritional deficiencies
0.265 0.735 0.000
M20.4 Other hammer toe(s) (acquired)
0.264 0.736 0.000
X20-X29 Contact with venomous animals and plants
0.264 0.736 0.000
E10-E14 Diabetes mellitus
0.264 0.736 0.000
M40-M43 Deforming dorsopathies
0.263 0.736 0.000
V40-V49 Car occupant injured in transport accident
0.263 0.737 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.263 0.737 0.000
M87 Osteonecrosis
0.263 0.737 0.000
M24.2 Disorder of ligament
0.262 0.737 0.000
M30 Polyarteritis nodosa and related conditions
0.262 0.738 0.000
F99-F99 Unspecified mental disorder
0.262 0.738 0.000
Q80-Q89 Other congenital malformations
0.261 0.738 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.261 0.738 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.261 0.739 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.260 0.740 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.260 0.740 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.259 0.741 0.000
M91-M94 Chondropathies
0.257 0.743 0.000
M14 Arthropathies in other diseases classified elsewhere
0.256 0.743 0.000
Y43.4 Immunosuppressive agents
0.256 0.744 0.000
M05 Seropositive rheumatoid arthritis
0.254 0.745 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.254 0.746 0.000
M24.0 Loose body in joint
0.254 0.746 0.000
M80 Osteoporosis with pathological fracture
0.254 0.746 0.000
G64 Other disorders of peripheral nervous system
0.254 0.746 0.000
G40.5 Special epileptic syndromes
0.253 0.746 0.000
M88 Paget's disease of bone [osteitis deformans]
0.253 0.747 0.000
G30 Alzheimer's disease
0.253 0.747 0.000
W50-W64 Exposure to animate mechanical forces
0.253 0.747 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.252 0.747 0.000
G41 Status epilepticus
0.252 0.747 0.000
G72 Other myopathies
0.252 0.748 0.000
Y57 Other and unspecified drugs and medicaments
0.252 0.748 0.000
X50 Overexertion and strenuous or repetitive movements
0.252 0.748 0.000
E73.8 Other lactose intolerance
0.252 0.748 0.000
E73.1 Secondary lactase deficiency
0.252 0.748 0.000
E73.0 Congenital lactase deficiency
0.252 0.748 0.000
Y35-Y36 Legal intervention and operations of war
0.251 0.749 0.000
Y10-Y34 Event of undetermined intent
0.251 0.749 0.000
Y00-Y09 Assault
0.251 0.749 0.000
X85-X99 Assault
0.251 0.749 0.000
X30-X39 Exposure to forces of nature
0.251 0.749 0.000
X10-X19 Contact with heat and hot substances
0.251 0.749 0.000
X00-X09 Exposure to smoke, fire and flames
0.251 0.749 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.251 0.749 0.000
W75-W84 Other accidental threats to breathing
0.251 0.749 0.000
W65-W74 Accidental drowning and submersion
0.251 0.749 0.000
V98-V99 Other and unspecified transport accidents
0.251 0.749 0.000
V95-V97 Air and space transport accidents
0.251 0.749 0.000
V90-V94 Water transport accidents
0.251 0.749 0.000
V70-V79 Bus occupant injured in transport accident
0.251 0.749 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.251 0.749 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.251 0.749 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.251 0.749 0.000
V01-V09 Pedestrian injured in transport accident
0.251 0.749 0.000
M13.9 Arthritis, unspecified
0.251 0.749 0.000
Y59 Other and unspecified vaccines and biological substances
0.251 0.749 0.000
Y58 Bacterial vaccines
0.251 0.749 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.251 0.749 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.251 0.749 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.251 0.749 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.251 0.749 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.251 0.749 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.251 0.749 0.000
Y48 Anaesthetics and therapeutic gases
0.251 0.749 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.251 0.749 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.251 0.749 0.000
V80-V89 Other land transport accidents
0.250 0.750 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.250 0.750 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.249 0.751 0.000
Q00-Q07 Congenital malformations of the nervous system
0.249 0.751 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.248 0.752 0.000
Y40 Systemic antibiotics
0.248 0.752 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.248 0.752 0.000
E80.6 Other disorders of bilirubin metabolism
0.248 0.752 0.000
E80.5 Crigler-Najjar syndrome
0.248 0.752 0.000
E80.3 Defects of catalase and peroxydase
0.248 0.752 0.000
E80.2 Other porphyria
0.248 0.752 0.000
E80.1 Porphyria cutanea tarda
0.248 0.752 0.000
E80.0 Hereditary erythropoietic porphyria
0.248 0.752 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.248 0.752 0.000
E00-E07 Disorders of thyroid gland
0.248 0.752 0.000
F80-F89 Disorders of psychological development
0.247 0.752 0.000
F30-F39 Mood [affective] disorders
0.247 0.753 0.000
Chapter IX Diseases of the circulatory system
0.247 0.753 0.000
Y42.5 Other oestrogens and progestogens
0.247 0.753 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.247 0.753 0.000
M33 Dermatopolymyositis
0.247 0.753 0.000
M32 Systemic lupus erythematosus
0.247 0.753 0.000
M84 Disorders of continuity of bone
0.247 0.753 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.247 0.753 0.000
M82 Osteoporosis in diseases classified elsewhere
0.246 0.754 0.000
G62 Other polyneuropathies
0.246 0.754 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.245 0.755 0.000
M34 Systemic sclerosis
0.245 0.755 0.000
F29 Unspecified nonorganic psychosis
0.245 0.755 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.245 0.755 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.245 0.755 0.000
F43 Reaction to severe stress, and adjustment disorders
0.243 0.757 0.000
M20.3 Other deformity of hallux (acquired)
0.243 0.757 0.000
E87.6 Hypokalaemia
0.243 0.757 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.243 0.757 0.000
E46 Unspecified protein-energy malnutrition
0.243 0.757 0.000
S20-S29 Injuries to the thorax
0.242 0.757 0.000
M06 Other rheumatoid arthritis
0.242 0.758 0.000
T31 Burns classified according to extent of body surface involved
0.242 0.758 0.000
I60-I69 Cerebrovascular diseases
0.242 0.758 0.000
G90-G99 Other disorders of the nervous system
0.242 0.758 0.000
M89.9 Disorder of bone, unspecified
0.241 0.759 0.000
M22.2 Patellofemoral disorders
0.241 0.759 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.241 0.759 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.241 0.759 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.241 0.759 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.241 0.759 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.241 0.759 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.241 0.759 0.000
G63.1 Polyneuropathy in neoplastic disease
0.241 0.759 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.241 0.759 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.241 0.759 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.240 0.760 0.000
E28 Ovarian dysfunction
0.240 0.760 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.239 0.761 0.000
M24.5 Contracture of joint
0.238 0.762 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.238 0.762 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.237 0.763 0.000
M62 Other disorders of muscle
0.237 0.763 0.000
M86.9 Osteomyelitis, unspecified
0.236 0.764 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.236 0.764 0.000
M31 Other necrotising vasculopathies
0.236 0.764 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.236 0.764 0.000
G60.0 Hereditary motor and sensory neuropathy
0.236 0.764 0.000
M86.6 Other chronic osteomyelitis
0.235 0.764 0.000
E27 Other disorders of adrenal gland
0.235 0.764 0.000
T79-T79 Certain early complications of trauma
0.235 0.765 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.235 0.765 0.000
Q35-Q37 Cleft lip and cleft palate
0.235 0.765 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.235 0.765 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.234 0.766 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.234 0.766 0.000
G45.0 Vertebro-basilar artery syndrome
0.234 0.766 0.000
Y45.2 Propionic acid derivatives
0.234 0.766 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.234 0.766 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.233 0.767 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.233 0.767 0.000
E70.3 Albinism
0.233 0.767 0.000
E70.2 Disorders of tyrosine metabolism
0.233 0.767 0.000
E70.1 Other hyperphenylalaninaemias
0.233 0.767 0.000
E70.0 Classical phenylketonuria
0.233 0.767 0.000
E71.3 Disorders of fatty-acid metabolism
0.233 0.767 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.233 0.767 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.233 0.767 0.000
E71.0 Maple-syrup-urine disease
0.233 0.767 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.233 0.767 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.233 0.767 0.000
E72.5 Disorders of glycine metabolism
0.233 0.767 0.000
E72.4 Disorders of ornithine metabolism
0.233 0.767 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.233 0.767 0.000
E72.2 Disorders of urea cycle metabolism
0.233 0.767 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.233 0.767 0.000
E72.0 Disorders of amino-acid transport
0.233 0.767 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.233 0.767 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.233 0.767 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.233 0.767 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.233 0.767 0.000
E74.2 Disorders of galactose metabolism
0.233 0.767 0.000
E74.1 Disorders of fructose metabolism
0.233 0.767 0.000
E74.0 Glycogen storage disease
0.233 0.767 0.000
E75.6 Lipid storage disorder, unspecified
0.233 0.767 0.000
E75.5 Other lipid storage disorders
0.233 0.767 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.233 0.767 0.000
E75.3 Sphingolipidosis, unspecified
0.233 0.767 0.000
E75.2 Other sphingolipidosis
0.233 0.767 0.000
E75.1 Other gangliosidosis
0.233 0.767 0.000
E75.0 GM2 gangliosidosis
0.233 0.767 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.233 0.767 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.233 0.767 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.233 0.767 0.000
E76.2 Other mucopolysaccharidoses
0.233 0.767 0.000
E76.1 Mucopolysaccharidosis, type II
0.233 0.767 0.000
E76.0 Mucopolysaccharidosis, type I
0.233 0.767 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.233 0.767 0.000
E77.8 Other disorders of glycoprotein metabolism
0.233 0.767 0.000
E77.1 Defects in glycoprotein degradation
0.233 0.767 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.233 0.767 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.233 0.767 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.233 0.767 0.000
E79.1 Lesch-Nyhan syndrome
0.233 0.767 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.233 0.767 0.000
E84.9 Cystic fibrosis, unspecified
0.233 0.767 0.000
E84.8 Cystic fibrosis with other manifestations
0.233 0.767 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.233 0.767 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.233 0.767 0.000
E85.9 Amyloidosis, unspecified
0.233 0.767 0.000
E85.8 Other amyloidosis
0.233 0.767 0.000
E85.4 Organ-limited amyloidosis
0.233 0.767 0.000
E85.3 Secondary systemic amyloidosis
0.233 0.767 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.233 0.767 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.233 0.767 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.233 0.767 0.000
Y43.9 Primarily systemic agent, unspecified
0.232 0.768 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.232 0.768 0.000
Y43.6 Enzymes, not elsewhere classified
0.232 0.768 0.000
Y43.5 Acidifying and alkalising agents
0.232 0.768 0.000
Y43.2 Antineoplastic natural products
0.232 0.768 0.000
Y43.1 Antineoplastic antimetabolites
0.232 0.768 0.000
Y43.0 Antiallergic and antiemetic drugs
0.232 0.768 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.232 0.768 0.000
T66-T78 Other and unspecified effects of external causes
0.232 0.768 0.000
M81.9 Osteoporosis, unspecified
0.232 0.768 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.231 0.769 0.000
M11 Other crystal arthropathies
0.231 0.769 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.231 0.769 0.000
F70-F79 Mental retardation
0.231 0.769 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.230 0.769 0.000
S12 Fracture of neck
0.230 0.770 0.000
M12 Other specific arthropathies
0.230 0.770 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.230 0.770 0.000
M08 Juvenile arthritis
0.230 0.770 0.000
Chapter XXII Codes for special purposes
0.230 0.770 0.000
M21 Other acquired deformities of limbs
0.229 0.771 0.000
M35 Other systemic involvement of connective tissue
0.229 0.771 0.000
S90-S99 Injuries to the ankle and foot
0.229 0.771 0.000
E23.2 Diabetes insipidus
0.229 0.771 0.000
M83 Adult osteomalacia
0.228 0.772 0.000
G45.3 Amaurosis fugax
0.228 0.772 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.228 0.772 0.000
F43.1 Posttraumatic stress disorder
0.228 0.772 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.228 0.772 0.000
E34 Other endocrine disorders
0.228 0.772 0.000
E32 Diseases of thymus
0.228 0.772 0.000
E31 Polyglandular dysfunction
0.228 0.772 0.000
E30 Disorders of puberty, not elsewhere classified
0.228 0.772 0.000
E26 Hyperaldosteronism
0.228 0.772 0.000
E25 Adrenogenital disorders
0.228 0.772 0.000
E24 Cushing's syndrome
0.228 0.772 0.000
E20 Hypoparathyroidism
0.228 0.772 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.227 0.773 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.227 0.773 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.227 0.773 0.000
M66 Spontaneous rupture of synovium and tendon
0.227 0.773 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.226 0.774 0.000
M24.9 Joint derangement, unspecified
0.226 0.774 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.226 0.774 0.000
M24.7 Protrusio acetabuli
0.226 0.774 0.000
M24.6 Ankylosis of joint
0.226 0.774 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.226 0.774 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.226 0.774 0.000
M07 Psoriatic and enteropathic arthropathies
0.226 0.774 0.000
X51 Travel and motion
0.226 0.774 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.225 0.775 0.000
T33-T35 Frostbite
0.225 0.775 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.225 0.775 0.000
T00-T07 Injuries involving multiple body regions
0.225 0.775 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.225 0.775 0.000
Y45.1 Salicylates
0.225 0.775 0.000
G40.8 Other epilepsy
0.225 0.775 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.225 0.775 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.225 0.775 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.225 0.775 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.225 0.775 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.224 0.776 0.000
E23.0 Hypopituitarism
0.224 0.776 0.000
I63 Cerebral infarction
0.224 0.776 0.000
Q50-Q56 Congenital malformations of genital organs
0.223 0.776 0.000
E65-E68 Obesity and other hyperalimentation
0.223 0.777 0.000
Q43 Other congenital malformations of intestine
0.222 0.777 0.000
M22.4 Chondromalacia patellae
0.222 0.778 0.000
E11 Non-insulin-dependent diabetes mellitus
0.222 0.778 0.000
M13.0 Polyarthritis, unspecified
0.222 0.778 0.000
G61.0 Guillain-Barre syndrome
0.222 0.778 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.222 0.778 0.000
G70 Myasthenia gravis and other myoneural disorders
0.221 0.779 0.000
Q60-Q64 Congenital malformations of the urinary system
0.221 0.779 0.000
I69 Sequelae of cerebrovascular disease
0.221 0.779 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.221 0.779 0.000
T31.0 Burns involving less than 10% of body surface
0.220 0.780 0.000
X50.4 Street and highway
0.220 0.780 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.220 0.780 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.219 0.781 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.219 0.781 0.000
S60-S69 Injuries to the wrist and hand
0.219 0.781 0.000
F99 Mental disorder, not otherwise specified
0.219 0.781 0.000
M90.7 Fracture of bone in neoplastic disease
0.219 0.781 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.219 0.781 0.000
E45 Retarded development following protein-energy malnutrition
0.219 0.781 0.000
E43 Unspecified severe protein-energy malnutrition
0.219 0.781 0.000
E42 Marasmic kwashiorkor
0.219 0.781 0.000
E41 Nutritional marasmus
0.219 0.781 0.000
E40 Kwashiorkor
0.219 0.781 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.219 0.781 0.000
Y45.8 Other analgesics and antipyretics
0.219 0.781 0.000
Y45.5 4-Aminophenol derivatives
0.219 0.781 0.000
Y45.4 Antirheumatics
0.219 0.781 0.000
S40-S49 Injuries to the shoulder and upper arm
0.219 0.781 0.000
I95 Hypotension
0.219 0.781 0.000
T63 Toxic effect of contact with venomous animals
0.218 0.782 0.000
G72.9 Myopathy, unspecified
0.218 0.782 0.000
X59 Exposure to unspecified factor
0.218 0.782 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.218 0.782 0.000
G61.1 Serum neuropathy
0.218 0.782 0.000
Chapter II Neoplasms
0.218 0.782 0.000
S50-S59 Injuries to the elbow and forearm
0.218 0.782 0.000
S80-S89 Injuries to the knee and lower leg
0.218 0.782 0.000
Chapter XIV Diseases of the genitourinary system
0.217 0.783 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.217 0.783 0.000
M23.4 Loose body in knee
0.217 0.783 0.000
V20-V29 Motorcycle rider injured in transport accident
0.216 0.783 0.000
Chapter I Certain infectious and parasitic diseases
0.216 0.784 0.000
G47.9 Sleep disorder, unspecified
0.216 0.784 0.000
G40.9 Epilepsy, unspecified
0.216 0.784 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.216 0.784 0.000
Y44.7 Plasma substitutes
0.216 0.784 0.000
Y44.6 Natural blood and blood products
0.216 0.784 0.000
Y44.5 Thrombolytic drugs
0.216 0.784 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.216 0.784 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.216 0.784 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.216 0.784 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.216 0.784 0.000
E06 Thyroiditis
0.216 0.784 0.000
S20 Superficial injury of thorax
0.215 0.784 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.215 0.785 0.000
G71 Primary disorders of muscles
0.215 0.785 0.000
G44.2 Tension-type headache
0.215 0.785 0.000
G30.9 Alzheimer's disease, unspecified
0.215 0.785 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.215 0.785 0.000
X58 Exposure to other specified factors
0.215 0.785 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.215 0.785 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.214 0.786 0.000
N40-N51 Diseases of male genital organs
0.214 0.786 0.000
Q85 Phakomatoses, not elsewhere classified
0.214 0.786 0.000
X78 Intentional self-harm by sharp object
0.214 0.786 0.000
W20-W49 Exposure to inanimate mechanical forces
0.214 0.786 0.000
M89.8 Other specified disorders of bone
0.214 0.786 0.000
W00-W19 Falls
0.214 0.786 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.214 0.786 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.213 0.786 0.000
G43 Migraine
0.213 0.787 0.000
X57 Unspecified privation
0.213 0.787 0.000
X54 Lack of water
0.213 0.787 0.000
X53 Lack of food
0.213 0.787 0.000
X52 Prolonged stay in weightless environment
0.213 0.787 0.000
M50-M54 Other dorsopathies
0.213 0.787 0.000
E55 Vitamin D deficiency
0.212 0.787 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.212 0.788 0.000
E29 Testicular dysfunction
0.212 0.788 0.000
E11.4 With neurological complications
0.212 0.788 0.000
F60-F69 Disorders of adult personality and behaviour
0.212 0.788 0.000
M20.0 Deformity of finger(s)
0.211 0.789 0.000
M00 Pyogenic arthritis
0.211 0.789 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.211 0.789 0.000
M14.6 Neuropathic arthropathy
0.211 0.789 0.000
M24.02 Loose body in joint (Upper arm)
0.210 0.790 0.000
M20.2 Hallux rigidus
0.210 0.790 0.000
V10-V19 Pedal cyclist injured in transport accident
0.210 0.790 0.000
M23.9 Internal derangement of knee, unspecified
0.210 0.790 0.000
M23.1 Discoid meniscus (congenital)
0.210 0.790 0.000
M23.0 Cystic meniscus
0.210 0.790 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.210 0.790 0.000
F42 Obsessive-compulsive disorder
0.210 0.790 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.210 0.790 0.000
D10-D36 Benign neoplasms
0.209 0.791 0.000
Y42.9 Other and unspecified hormone antagonists
0.208 0.792 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.208 0.792 0.000
Y42.4 Oral contraceptives
0.208 0.792 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.208 0.792 0.000
Y42.2 Antithyroid drugs
0.208 0.792 0.000
Y42.1 Thyroid hormones and substitutes
0.208 0.792 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.208 0.792 0.000
M43 Other deforming dorsopathies
0.208 0.792 0.000
M86.8 Other osteomyelitis
0.208 0.792 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.208 0.792 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.208 0.792 0.000
M86.3 Chronic multifocal osteomyelitis
0.208 0.792 0.000
M86.2 Subacute osteomyelitis
0.208 0.792 0.000
M86.1 Other acute osteomyelitis
0.208 0.792 0.000
M86.0 Acute haematogenous osteomyelitis
0.208 0.792 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.208 0.792 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.207 0.793 0.000
Q76 Congenital malformations of spine and bony thorax
0.207 0.793 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.207 0.793 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.206 0.794 0.000
M61 Calcification and ossification of muscle
0.206 0.794 0.000
M60 Myositis
0.206 0.794 0.000
I63.9 Cerebral infarction, unspecified
0.206 0.794 0.000
M24.24 Disorder of ligament (Hand)
0.205 0.795 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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