TreeWAS – Variant ID: rs118036280

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000
C79 Secondary malignant neoplasm of other sites	0.998	0.002
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.998	0.002
D60-D64 Aplastic and other anaemias	0.998	0.002
Chapter I Certain infectious and parasitic diseases	0.996	0.004
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.991	0.009
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.989	0.011
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.986	0.014
Chapter XIV Diseases of the genitourinary system	0.985	0.015
A30-A49 Other bacterial diseases	0.983	0.017
M20-M25 Other joint disorders	0.983	0.017
D64 Other anaemias	0.969	0.031
D61 Other aplastic anaemias	0.969	0.031
Chapter XX External causes of morbidity and mortality	0.965	0.035
D50-D53 Nutritional anaemias	0.958	0.042
N10-N16 Renal tubulo-interstitial diseases	0.955	0.045
M23 Internal derangement of knee	0.955	0.045
B35-B49 Mycoses	0.951	0.049
C77.1 Intrathoracic lymph nodes	0.950	0.050
D64.9 Anaemia, unspecified	0.949	0.051
D61.9 Aplastic anaemia, unspecified	0.949	0.051
M45-M49 Spondylopathies	0.948	0.052
C64-C68 Malignant neoplasms of urinary tract	0.939	0.061
M48 Other spondylopathies	0.935	0.065
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.935	0.065
D70-D77 Other diseases of blood and blood-forming organs	0.933	0.067
Chapter IV Endocrine, nutritional and metabolic diseases	0.930	0.070
A41 Other septicaemia	0.929	0.071
M48.0 Spinal stenosis	0.926	0.074
M23.2 Derangement of meniscus due to old tear or injury	0.925	0.075
C78.0 Secondary malignant neoplasm of lung	0.925	0.075
C78.2 Secondary malignant neoplasm of pleura	0.925	0.075
M24 Other specific joint derangements	0.924	0.076
N60-N64 Disorders of breast	0.918	0.082
N17-N19 Renal failure	0.916	0.084
M48.06 Spinal stenosis (Lumbar region)	0.915	0.085
C79.9 Secondary malignant neoplasm, unspecified site	0.910	0.090
C60-C63 Malignant neoplasms of male genital organs	0.908	0.092
C78.7 Secondary malignant neoplasm of liver	0.906	0.094
C77.0 Lymph nodes of head, face and neck	0.905	0.095
E87 Other disorders of fluid, electrolyte and acid-base balance	0.904	0.096
E70-E90 Metabolic disorders	0.904	0.096
B37 Candidiasis	0.902	0.098
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.902	0.098
E87.1 Hypo-osmolality and hyponatraemia	0.900	0.100
C80 Malignant neoplasm without specification of site	0.895	0.105
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.892	0.108
D70 Agranulocytosis	0.884	0.116
C77.8 Lymph nodes of multiple regions	0.883	0.117
A49 Bacterial infection of unspecified site	0.881	0.119
N63 Unspecified lump in breast	0.880	0.120
C67 Malignant neoplasm of bladder	0.877	0.123
D51 Vitamin B12 deficiency anaemia	0.874	0.126
C79.2 Secondary malignant neoplasm of skin	0.874	0.126
D50 Iron deficiency anaemia	0.867	0.133
C51-C58 Malignant neoplasms of female genital organs	0.864	0.136
M24.1 Other articular cartilage disorders	0.863	0.137
Chapter XII Diseases of the skin and subcutaneous tissue	0.863	0.137
Chapter IX Diseases of the circulatory system	0.855	0.145
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.852	0.148
L00-L08 Infections of the skin and subcutaneous tissue	0.851	0.149
L02 Cutaneous abscess, furuncle and carbuncle	0.848	0.152
N13 Obstructive and reflux uropathy	0.846	0.154
A40 Streptococcal septicaemia	0.845	0.155
N17 Acute renal failure	0.845	0.155
I05-I09 Chronic rheumatic heart diseases	0.843	0.157
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.842	0.158
C61 Malignant neoplasm of prostate	0.840	0.160
D63 Anaemia in chronic diseases classified elsewhere	0.838	0.162
M22 Disorders of patella	0.837	0.163
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.836	0.164
I08 Multiple valve diseases	0.835	0.165
Chapter VI Diseases of the nervous system	0.834	0.166
B37.8 Candidiasis of other sites	0.834	0.166
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.831	0.169
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.828	0.171
R50-R69 General symptoms and signs	0.828	0.172
C77.2 Intra-abdominal lymph nodes	0.826	0.174
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.823	0.177
C77.4 Inguinal and lower limb lymph nodes	0.822	0.178
N19 Unspecified renal failure	0.817	0.183
M23.4 Loose body in knee	0.816	0.184
I70-I79 Diseases of arteries, arterioles and capillaries	0.816	0.184
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.816	0.184
R53 Malaise and fatigue	0.815	0.185
M24.16 Other articular cartilage disorders (Lower leg)	0.814	0.186
A41.1 Septicaemia due to other specified staphylococcus	0.812	0.188
R52 Pain, not elsewhere classified	0.810	0.190
M86-M90 Other osteopathies	0.808	0.192
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.808	0.192
V40-V49 Car occupant injured in transport accident	0.807	0.193
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.805	0.195
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.803	0.197
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.803	0.197
D50.8 Other iron deficiency anaemias	0.802	0.198
D80-D89 Certain disorders involving the immune mechanism	0.802	0.198
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.801	0.199
E87.7 Fluid overload	0.799	0.201
M30 Polyarteritis nodosa and related conditions	0.799	0.201
A41.5 Septicaemia due to other Gram-negative organisms	0.797	0.203
N17.9 Acute renal failure, unspecified	0.795	0.205
N00-N08 Glomerular diseases	0.791	0.209
Y43 Primarily systemic agents	0.790	0.210
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.790	0.210
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.785	0.215
B90-B94 Sequelae of infectious and parasitic diseases	0.783	0.217
B50-B64 Protozoal diseases	0.782	0.218
B20-B24 Human immunodeficiency virus [HIV] disease	0.781	0.219
I08.0 Disorders of both mitral and aortic valves	0.780	0.220
N30-N39 Other diseases of urinary system	0.779	0.221
N13.3 Other and unspecified hydronephrosis	0.778	0.222
G90-G99 Other disorders of the nervous system	0.776	0.224
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.776	0.224
Y41 Other systemic anti-infectives and antiparasitics	0.775	0.225
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.774	0.226
A41.0 Septicaemia due to Staphylococcus aureus	0.774	0.226
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.772	0.228
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.769	0.231
E20-E35 Disorders of other endocrine glands	0.768	0.232
B65-B83 Helminthiases	0.767	0.233
M23.0 Cystic meniscus	0.767	0.233
N61 Inflammatory disorders of breast	0.765	0.235
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.765	0.235
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.763	0.237
C80.0 Malignant neoplasm, primary site unknown, so stated	0.763	0.237
M48.02 Spinal stenosis (Cervical region)	0.763	0.237
M05-M14 Inflammatory polyarthropathies	0.762	0.238
A41.2 Septicaemia due to unspecified staphylococcus	0.760	0.240
Chapter XXII Codes for special purposes	0.760	0.240
M21 Other acquired deformities of limbs	0.760	0.240
B37.9 Candidiasis, unspecified	0.759	0.241
A49.9 Bacterial infection, unspecified	0.759	0.241
A49.8 Other bacterial infections of unspecified site	0.757	0.243
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.756	0.244
C64 Malignant neoplasm of kidney, except renal pelvis	0.756	0.244
Y60-Y69 Misadventures to patients during surgical and medical care	0.755	0.245
M31 Other necrotising vasculopathies	0.753	0.247
B49 Unspecified mycosis	0.752	0.248
R52.0 Acute pain	0.751	0.249
G40-G47 Episodic and paroxysmal disorders	0.751	0.249
C80.9 Malignant neoplasm, unspecified	0.749	0.250
C55 Malignant neoplasm of uterus, part unspecified	0.746	0.254
A40.8 Other streptococcal septicaemia	0.746	0.254
X60-X84 Intentional self-harm	0.746	0.254
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.746	0.254
Y46 Antiepileptics and anti-Parkinsonism drugs	0.746	0.254
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.744	0.256
A46 Erysipelas	0.737	0.263
W00-W19 Falls	0.737	0.263
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.736	0.264
E87.5 Hyperkalaemia	0.736	0.264
W20-W49 Exposure to inanimate mechanical forces	0.734	0.266
D73 Diseases of spleen	0.733	0.267
M23.6 Other spontaneous disruption of ligament(s) of knee	0.731	0.269
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.729	0.271
I08.1 Disorders of both mitral and tricuspid valves	0.729	0.271
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.728	0.272
D55-D59 Haemolytic anaemias	0.727	0.273
N03 Chronic nephritic syndrome	0.726	0.274
R52.1 Chronic intractable pain	0.725	0.275
M35 Other systemic involvement of connective tissue	0.722	0.278
M24.4 Recurrent dislocation and subluxation of joint	0.721	0.279
B35 Dermatophytosis	0.721	0.279
I71 Aortic aneurysm and dissection	0.720	0.280
D62 Acute posthaemorrhagic anaemia	0.719	0.281
R47-R49 Symptoms and signs involving speech and voice	0.718	0.282
M23.49 Loose body in knee-Unspec lig/men	0.717	0.283
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.715	0.284
C78.4 Secondary malignant neoplasm of small intestine	0.715	0.285
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.715	0.285
C78.1 Secondary malignant neoplasm of mediastinum	0.715	0.285
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.715	0.285
C67.4 Posterior wall of bladder	0.715	0.285
B99-B99 Other infectious diseases	0.714	0.286
B85-B89 Pediculosis, acariasis and other infestations	0.714	0.286
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.714	0.286
A75-A79 Rickettsioses	0.714	0.286
A70-A74 Other diseases caused by chlamydiae	0.714	0.286
A65-A69 Other spirochaetal diseases	0.714	0.286
A20-A28 Certain zoonotic bacterial diseases	0.714	0.286
A15-A19 Tuberculosis	0.714	0.286
Y42.7 Androgens and anabolic congeners	0.712	0.288
M60-M63 Disorders of muscles	0.711	0.289
M00-M03 Infectious arthropathies	0.711	0.289
A50-A64 Infections with a predominantly sexual mode of transmission	0.710	0.290
N64 Other disorders of breast	0.710	0.290
C67.8 Overlapping lesion of bladder	0.709	0.291
M48.09 Spinal stenosis (Site unspecified)	0.709	0.291
E83 Disorders of mineral metabolism	0.707	0.293
V20-V29 Motorcycle rider injured in transport accident	0.706	0.294
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.706	0.294
W50-W64 Exposure to animate mechanical forces	0.706	0.294
B15-B19 Viral hepatitis	0.706	0.294
A48 Other bacterial diseases, not elsewhere classified	0.705	0.295
A44 Bartonellosis	0.705	0.295
A43 Nocardiosis	0.705	0.295
A42 Actinomycosis	0.705	0.295
A39 Meningococcal infection	0.705	0.295
A37 Whooping cough	0.705	0.295
A36 Diphtheria	0.705	0.295
A32 Listeriosis	0.705	0.295
A31 Infection due to other mycobacteria	0.705	0.295
A30 Leprosy [Hansen's disease]	0.705	0.295
A38 Scarlet fever	0.705	0.295
A35 Other tetanus	0.705	0.295
A34 Obstetrical tetanus	0.705	0.295
A33 Tetanus neonatorum	0.705	0.295
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.705	0.295
M33 Dermatopolymyositis	0.705	0.295
M32 Systemic lupus erythematosus	0.705	0.295
Y57 Other and unspecified drugs and medicaments	0.704	0.296
C56 Malignant neoplasm of ovary	0.701	0.299
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.699	0.301
C67.5 Bladder neck	0.698	0.302
I08.2 Disorders of both aortic and tricuspid valves	0.697	0.303
D64.8 Other specified anaemias	0.695	0.305
D64.4 Congenital dyserythropoietic anaemia	0.695	0.305
D64.3 Other sideroblastic anaemias	0.695	0.305
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.695	0.305
D64.1 Secondary sideroblastic anaemia due to disease	0.695	0.305
D64.0 Hereditary sideroblastic anaemia	0.695	0.305
D61.8 Other specified aplastic anaemias	0.695	0.305
D61.3 Idiopathic aplastic anaemia	0.695	0.305
D61.2 Aplastic anaemia due to other external agents	0.695	0.305
D61.1 Drug-induced aplastic anaemia	0.695	0.305
D61.0 Constitutional aplastic anaemia	0.695	0.305
C34 Malignant neoplasm of bronchus and lung	0.694	0.306
V49 Car occupant injured in other and unspecified transport accidents	0.694	0.306
N99-N99 Other disorders of the genitourinary system	0.694	0.306
M34 Systemic sclerosis	0.693	0.307
I70 Atherosclerosis	0.693	0.307
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.693	0.307
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.692	0.308
Y35-Y36 Legal intervention and operations of war	0.692	0.308
Y10-Y34 Event of undetermined intent	0.692	0.308
Y00-Y09 Assault	0.692	0.308
X85-X99 Assault	0.692	0.308
X58-X59 Accidental exposure to other and unspecified factors	0.692	0.308
X50-X57 Overexertion, travel and privation	0.692	0.308
X30-X39 Exposure to forces of nature	0.692	0.308
X20-X29 Contact with venomous animals and plants	0.692	0.308
X10-X19 Contact with heat and hot substances	0.692	0.308
X00-X09 Exposure to smoke, fire and flames	0.692	0.308
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.692	0.308
W75-W84 Other accidental threats to breathing	0.692	0.308
W65-W74 Accidental drowning and submersion	0.692	0.308
V98-V99 Other and unspecified transport accidents	0.692	0.308
V95-V97 Air and space transport accidents	0.692	0.308
V90-V94 Water transport accidents	0.692	0.308
V80-V89 Other land transport accidents	0.692	0.308
V70-V79 Bus occupant injured in transport accident	0.692	0.308
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.692	0.308
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.692	0.308
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.692	0.308
V01-V09 Pedestrian injured in transport accident	0.692	0.308
C79.6 Secondary malignant neoplasm of ovary	0.691	0.308
A80-A89 Viral infections of the central nervous system	0.689	0.311
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.689	0.311
M24.5 Contracture of joint	0.688	0.311
N13.4 Hydroureter	0.688	0.312
C91 Lymphoid leukaemia	0.688	0.312
M90 Osteopathies in diseases classified elsewhere	0.688	0.312
D53 Other nutritional anaemias	0.687	0.313
I77 Other disorders of arteries and arterioles	0.686	0.314
E87.2 Acidosis	0.685	0.315
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.685	0.315
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.685	0.315
N15 Other renal tubulo-interstitial diseases	0.685	0.315
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.685	0.315
M23.9 Internal derangement of knee, unspecified	0.684	0.315
M23.1 Discoid meniscus (congenital)	0.684	0.315
N70-N77 Inflammatory diseases of female pelvic organs	0.684	0.316
N11 Chronic tubulo-interstitial nephritis	0.683	0.317
M91-M94 Chondropathies	0.683	0.317
B25-B34 Other viral diseases	0.683	0.317
N10 Acute tubulo-interstitial nephritis	0.682	0.317
B48 Other mycoses, not elsewhere classified	0.682	0.318
B47 Mycetoma	0.682	0.318
B46 Zygomycosis	0.682	0.318
B45 Cryptococcosis	0.682	0.318
B43 Chromomycosis and phaeomycotic abscess	0.682	0.318
B42 Sporotrichosis	0.682	0.318
B41 Paracoccidioidomycosis	0.682	0.318
B40 Blastomycosis	0.682	0.318
B39 Histoplasmosis	0.682	0.318
B38 Coccidioidomycosis	0.682	0.318
B36 Other superficial mycoses	0.682	0.318
G47 Sleep disorders	0.682	0.318
N13.8 Other obstructive and reflux uropathy	0.681	0.319
N03.9 Unspecified	0.680	0.320
M49 Spondylopathies in diseases classified elsewhere	0.680	0.320
E50-E64 Other nutritional deficiencies	0.679	0.320
C53 Malignant neoplasm of cervix uteri	0.677	0.323
D63.0 Anaemia in neoplastic disease	0.677	0.323
L50-L54 Urticaria and erythema	0.677	0.323
M22.2 Patellofemoral disorders	0.676	0.324
Y43.4 Immunosuppressive agents	0.676	0.324
I73 Other peripheral vascular diseases	0.675	0.325
C67.3 Anterior wall of bladder	0.675	0.325
B44 Aspergillosis	0.675	0.325
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.675	0.325
C68 Malignant neoplasm of other and unspecified urinary organs	0.674	0.326
C66 Malignant neoplasm of ureter	0.674	0.326
C65 Malignant neoplasm of renal pelvis	0.674	0.326
Q50-Q56 Congenital malformations of genital organs	0.673	0.326
R49 Voice disturbances	0.673	0.326
S90-S99 Injuries to the ankle and foot	0.672	0.328
L08 Other local infections of skin and subcutaneous tissue	0.672	0.328
M48.00 Spinal stenosis (Multiple sites in spine)	0.672	0.328
L20-L30 Dermatitis and eczema	0.672	0.328
M65-M68 Disorders of synovium and tendon	0.671	0.329
R60 Oedema, not elsewhere classified	0.671	0.329
R21 Rash and other nonspecific skin eruption	0.671	0.329
Chapter VIII Diseases of the ear and mastoid process	0.671	0.329
M48.9 Spondylopathy, unspecified	0.670	0.330
M48.8 Other specified spondylopathies	0.670	0.330
M48.4 Fatigue fracture of vertebra	0.670	0.330
M48.3 Traumatic spondylopathy	0.670	0.330
M48.2 Kissing spine	0.670	0.330
M48.1 Ankylosing hyperostosis [Forestier]	0.670	0.330
Y59 Other and unspecified vaccines and biological substances	0.670	0.330
Y58 Bacterial vaccines	0.670	0.330
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.670	0.330
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.670	0.330
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.670	0.330
Y53 Agents primarily affecting the gastro-intestinal system	0.670	0.330
Y52 Agents primarily affecting the cardiovascular system	0.670	0.330
Y50 Central nervous system stimulants, not elsewhere classified	0.670	0.330
Y49 Psychotropic drugs, not elsewhere classified	0.670	0.330
Y48 Anaesthetics and therapeutic gases	0.670	0.330
Y47 Sedatives, hypnotics and antianxiety drugs	0.670	0.330
M45 Ankylosing spondylitis	0.669	0.330
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.669	0.331
D74 Methaemoglobinaemia	0.669	0.331
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.669	0.331
D71 Functional disorders of polymorphonuclear neutrophils	0.669	0.331
D63.8 Anaemia in other chronic diseases classified elsewhere	0.668	0.332
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.667	0.333
E40-E46 Malnutrition	0.667	0.333
M24.0 Loose body in joint	0.666	0.334
D52 Folate deficiency anaemia	0.666	0.334
A41.4 Septicaemia due to anaerobes	0.666	0.334
A41.3 Septicaemia due to Haemophilus influenzae	0.666	0.334
M22.4 Chondromalacia patellae	0.666	0.334
M23.3 Other meniscus derangements	0.665	0.335
M48.5 Collapsed vertebra, not elsewhere classified	0.665	0.335
B37.0 Candidal stomatitis	0.665	0.335
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.664	0.336
M48.05 Spinal stenosis (Thoracolumbar region)	0.664	0.336
M48.04 Spinal stenosis (Thoracic region)	0.664	0.336
M48.03 Spinal stenosis (Cervicothoracic region)	0.664	0.336
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.664	0.336
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.663	0.336
M24.9 Joint derangement, unspecified	0.663	0.337
M24.8 Other specific joint derangements, not elsewhere classified	0.663	0.337
M24.7 Protrusio acetabuli	0.663	0.337
M24.6 Ankylosis of joint	0.663	0.337
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.663	0.337
M24.2 Disorder of ligament	0.663	0.337
C90 Multiple myeloma and malignant plasma cell neoplasms	0.663	0.337
G99 Other disorders of nervous system in diseases classified elsewhere	0.663	0.337
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.662	0.338
Y45.0 Opioids and related analgesics	0.662	0.338
C62 Malignant neoplasm of testis	0.660	0.339
C67.2 Lateral wall of bladder	0.660	0.340
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.660	0.340
D75 Other diseases of blood and blood-forming organs	0.659	0.341
E16 Other disorders of pancreatic internal secretion	0.659	0.341
R59 Enlarged lymph nodes	0.659	0.341
S10-S19 Injuries to the neck	0.658	0.342
E73 Lactose intolerance	0.658	0.342
V10-V19 Pedal cyclist injured in transport accident	0.657	0.342
Z51 Other medical care	0.656	0.344
C67.1 Dome of bladder	0.656	0.344
M23.5 Chronic instability of knee	0.655	0.345
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.655	0.345
Chapter XXI Factors influencing health status and contact with health services	0.654	0.346
M40-M43 Deforming dorsopathies	0.654	0.346
N13.6 Pyonephrosis	0.654	0.346
C67.9 Bladder, unspecified	0.653	0.347
Z40-Z54 Persons encountering health services for specific procedures and health care	0.653	0.347
C63 Malignant neoplasm of other and unspecified male genital organs	0.651	0.349
C60 Malignant neoplasm of penis	0.651	0.349
Y44 Agents primarily affecting blood constituents	0.650	0.349
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.649	0.351
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.649	0.351
Y45.1 Salicylates	0.648	0.351
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.648	0.352
E87.4 Mixed disorder of acid-base balance	0.648	0.352
E87.3 Alkalosis	0.648	0.352
E85 Amyloidosis	0.648	0.352
E84 Cystic fibrosis	0.648	0.352
E79 Disorders of purine and pyrimidine metabolism	0.648	0.352
E77 Disorders of glycoprotein metabolism	0.648	0.352
E76 Disorders of glycosaminoglycan metabolism	0.648	0.352
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.648	0.352
E74 Other disorders of carbohydrate metabolism	0.648	0.352
E72 Other disorders of amino-acid metabolism	0.648	0.352
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.648	0.352
E70 Disorders of aromatic amino-acid metabolism	0.648	0.352
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.648	0.352
Y51 Drugs primarily affecting the autonomic nervous system	0.648	0.352
B37.3 Candidiasis of vulva and vagina	0.648	0.352
N40-N51 Diseases of male genital organs	0.647	0.353
B37.7 Candidal septicaemia	0.647	0.353
B37.6 Candidal endocarditis	0.647	0.353
B37.5 Candidal meningitis	0.647	0.353
B37.4 Candidiasis of other urogenital sites	0.647	0.353
B37.2 Candidiasis of skin and nail	0.647	0.353
B37.1 Pulmonary candidiasis	0.647	0.353
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.645	0.355
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.644	0.356
I05 Rheumatic mitral valve diseases	0.643	0.357
X40-X49 Accidental poisoning by and exposure to noxious substances	0.643	0.357
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.643	0.357
R52.9 Pain, unspecified	0.642	0.358
R49.0 Dysphonia	0.642	0.358
M25 Other joint disorders, not elsewhere classified	0.641	0.359
C77.9 Lymph node, unspecified	0.639	0.361
W22 Striking against or struck by other objects	0.638	0.362
E88 Other metabolic disorders	0.638	0.362
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.637	0.362
C79.8 Secondary malignant neoplasm of other specified sites	0.637	0.362
G93 Other disorders of brain	0.636	0.363
D84 Other immunodeficiencies	0.636	0.364
S50-S59 Injuries to the elbow and forearm	0.636	0.364
G95 Other diseases of spinal cord	0.635	0.365
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.632	0.368
A49.3 Mycoplasma infection, unspecified	0.632	0.368
A49.2 Haemophilus influenzae infection, unspecified	0.632	0.368
E80 Disorders of porphyrin and bilirubin metabolism	0.630	0.370
B91 Sequelae of poliomyelitis	0.630	0.370
T66-T78 Other and unspecified effects of external causes	0.630	0.370
B59 Pneumocystosis	0.629	0.371
Z51.5 Palliative care	0.629	0.371
C67.7 Urachus	0.628	0.371
C67.0 Trigone of bladder	0.628	0.371
M05 Seropositive rheumatoid arthritis	0.628	0.372
B24 Unspecified human immunodeficiency virus [HIV] disease	0.627	0.373
D51.8 Other vitamin B12 deficiency anaemias	0.626	0.373
D51.3 Other dietary vitamin B12 deficiency anaemia	0.626	0.373
D51.2 Transcobalamin II deficiency	0.626	0.373
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.626	0.373
C67.6 Ureteric orifice	0.626	0.374
A49.1 Streptococcal infection, unspecified	0.625	0.375
N39 Other disorders of urinary system	0.624	0.376
C79.7 Secondary malignant neoplasm of adrenal gland	0.624	0.376
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.624	0.376
M06 Other rheumatoid arthritis	0.624	0.376
E34 Other endocrine disorders	0.624	0.376
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.623	0.377
R25 Abnormal involuntary movements	0.622	0.378
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.622	0.378
D50.1 Sideropenic dysphagia	0.621	0.378
M22.8 Other disorders of patella	0.621	0.378
N64.8 Other specified disorders of breast	0.621	0.379
R68 Other general symptoms and signs	0.621	0.379
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.621	0.379
R52.2 Other chronic pain	0.621	0.379
D50.9 Iron deficiency anaemia, unspecified	0.619	0.381
C57 Malignant neoplasm of other and unspecified female genital organs	0.619	0.381
C51 Malignant neoplasm of vulva	0.619	0.381
C58 Malignant neoplasm of placenta	0.619	0.381
C52 Malignant neoplasm of vagina	0.619	0.381
M24.19 Other articular cartilage disorders (Site unspecified)	0.619	0.381
M24.18 Other articular cartilage disorders (Other)	0.619	0.381
M24.17 Other articular cartilage disorders (Ankle and foot)	0.619	0.381
M24.14 Other articular cartilage disorders (Hand)	0.619	0.381
M24.13 Other articular cartilage disorders (Forearm)	0.619	0.381
M24.12 Other articular cartilage disorders (Upper arm)	0.619	0.381
M24.11 Other articular cartilage disorders (Shoulder region)	0.619	0.381
M24.10 Other articular cartilage disorders (Multiple sites)	0.619	0.381
L10-L14 Bullous disorders	0.619	0.381
M50-M54 Other dorsopathies	0.619	0.381
C50-C50 Malignant neoplasm of breast	0.618	0.382
Z43 Attention to artificial openings	0.618	0.382
A00-A09 Intestinal infectious diseases	0.617	0.383
R58 Haemorrhage, not elsewhere classified	0.617	0.383
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.617	0.383
Z51.8 Other specified medical care	0.616	0.384
S70-S79 Injuries to the hip and thigh	0.615	0.385
E83.5 Disorders of calcium metabolism	0.615	0.385
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.615	0.385
M46 Other inflammatory spondylopathies	0.614	0.386
I00-I02 Acute rheumatic fever	0.613	0.387
V49.9 Car occupant [any] injured in unspecified traffic accident	0.613	0.387
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.613	0.387
G90 Disorders of autonomic nervous system	0.613	0.387
G47.3 Sleep apnoea	0.612	0.388
R95-R99 Ill-defined and unknown causes of mortality	0.611	0.389
E87.6 Hypokalaemia	0.611	0.389
D72 Other disorders of white blood cells	0.610	0.389
L04 Acute lymphadenitis	0.610	0.390

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations