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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118166304
log Bayes Factor = 25.1727
Chromosome 17   position 48,951,566  (GRCh37) Explore rs118166304 on Ensembl!
Variant rs118166304 is part of Cluster X0045

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
K22 Other diseases of oesophagus
0.997 0.003 0.000
K21 Gastro-oesophageal reflux disease
0.997 0.003 0.000
E65-E68 Obesity and other hyperalimentation
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.993 0.007 0.000
B95-B98 Bacterial, viral and other infectious agents
0.993 0.007 0.000
E66 Obesity
0.992 0.008 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.991 0.009 0.000
E66.9 Obesity, unspecified
0.990 0.010 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.990 0.010 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.989 0.011 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.988 0.012 0.000
Chapter X Diseases of the respiratory system
0.987 0.013 0.000
Z86 Personal history of certain other diseases
0.986 0.014 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.985 0.015 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.017 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.983 0.017 0.000
N17-N19 Renal failure
0.982 0.018 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.981 0.019 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.979 0.021 0.000
A00-A09 Intestinal infectious diseases
0.979 0.021 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.975 0.025 0.000
E87.5 Hyperkalaemia
0.973 0.027 0.000
N18 Chronic renal failure
0.973 0.027 0.000
K22.1 Ulcer of oesophagus
0.968 0.032 0.000
Z86.7 Personal history of diseases of the circulatory system
0.967 0.033 0.000
K70-K77 Diseases of liver
0.966 0.034 0.000
I60-I69 Cerebrovascular diseases
0.966 0.034 0.000
A30-A49 Other bacterial diseases
0.964 0.036 0.000
Chapter II Neoplasms
0.963 0.037 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.961 0.039 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.959 0.041 0.000
Z95.2 Presence of prosthetic heart valve
0.955 0.045 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.952 0.048 0.000
I10-I15 Hypertensive diseases
0.950 0.050 0.000
K29 Gastritis and duodenitis
0.950 0.050 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.947 0.053 0.000
D10-D36 Benign neoplasms
0.946 0.054 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.945 0.055 0.000
N18.9 Chronic renal failure, unspecified
0.944 0.056 0.000
I50 Heart failure
0.944 0.056 0.000
Chapter V Mental and behavioural disorders
0.943 0.057 0.000
Z13 Special screening examination for other diseases and disorders
0.942 0.058 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.939 0.061 0.000
A41 Other septicaemia
0.933 0.067 0.000
I34 Nonrheumatic mitral valve disorders
0.928 0.072 0.000
Z04 Examination and observation for other reasons
0.928 0.072 0.000
K29.8 Duodenitis
0.926 0.074 0.000
R79 Other abnormal findings of blood chemistry
0.926 0.074 0.000
D27 Benign neoplasm of ovary
0.925 0.075 0.000
I50.1 Left ventricular failure
0.924 0.076 0.000
R50-R69 General symptoms and signs
0.917 0.083 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.915 0.085 0.000
Z95.0 Presence of cardiac pacemaker
0.911 0.089 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.910 0.090 0.000
J81 Pulmonary oedema
0.908 0.092 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.906 0.094 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.905 0.095 0.000
N19 Unspecified renal failure
0.904 0.096 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.903 0.097 0.000
R55 Syncope and collapse
0.901 0.099 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.900 0.100 0.000
K22.9 Disease of oesophagus, unspecified
0.900 0.100 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.899 0.101 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.896 0.104 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.895 0.105 0.000
N99-N99 Other disorders of the genitourinary system
0.892 0.108 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.890 0.110 0.000
C50-C50 Malignant neoplasm of breast
0.887 0.113 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.883 0.117 0.000
T81 Complications of procedures, not elsewhere classified
0.881 0.119 0.000
I47 Paroxysmal tachycardia
0.881 0.119 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.881 0.119 0.000
K31 Other diseases of stomach and duodenum
0.880 0.120 0.000
J30-J39 Other diseases of upper respiratory tract
0.880 0.120 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.880 0.120 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.879 0.121 0.000
I12 Hypertensive renal disease
0.877 0.123 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.876 0.124 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.875 0.125 0.000
Chapter VI Diseases of the nervous system
0.874 0.126 0.000
Z95.1 Presence of aortocoronary bypass graft
0.872 0.128 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.869 0.131 0.000
Z53.8 Procedure not carried out for other reasons
0.867 0.133 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.865 0.135 0.000
I34.0 Mitral (valve) insufficiency
0.864 0.136 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.863 0.137 0.000
E83 Disorders of mineral metabolism
0.862 0.138 0.000
K74 Fibrosis and cirrhosis of liver
0.861 0.139 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.857 0.143 0.000
I35 Nonrheumatic aortic valve disorders
0.855 0.145 0.000
N30-N39 Other diseases of urinary system
0.853 0.147 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.853 0.147 0.000
Z02 Examination and encounter for administrative purposes
0.852 0.148 0.000
R73 Elevated blood glucose level
0.850 0.150 0.000
K31.7 Polyp of stomach and duodenum
0.849 0.151 0.000
K26 Duodenal ulcer
0.848 0.152 0.000
Z36 Antenatal screening
0.848 0.152 0.000
Z50 Care involving use of rehabilitation procedures
0.847 0.153 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.847 0.153 0.000
K65-K67 Diseases of peritoneum
0.846 0.154 0.000
Z48 Other surgical follow-up care
0.846 0.154 0.000
A08 Viral and other specified intestinal infections
0.844 0.156 0.000
A41.9 Septicaemia, unspecified
0.843 0.157 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.839 0.161 0.000
K25 Gastric ulcer
0.838 0.162 0.000
Z94 Transplanted organ and tissue status
0.837 0.163 0.000
N17 Acute renal failure
0.836 0.164 0.000
K50-K52 Noninfective enteritis and colitis
0.834 0.166 0.000
N18.0 End-stage renal disease
0.834 0.166 0.000
E00-E07 Disorders of thyroid gland
0.833 0.167 0.000
C50 Malignant neoplasm of breast
0.833 0.167 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.831 0.169 0.000
N18.3 Chronic kidney disease, stage 3
0.830 0.170 0.000
N30 Cystitis
0.830 0.170 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.828 0.172 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.827 0.173 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.827 0.173 0.000
I20-I25 Ischaemic heart diseases
0.826 0.174 0.000
E89.0 Postprocedural hypothyroidism
0.824 0.176 0.000
I10 Essential (primary) hypertension
0.821 0.179 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.820 0.180 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.819 0.181 0.000
T93 Sequelae of injuries of lower limb
0.819 0.181 0.000
I65.2 Occlusion and stenosis of carotid artery
0.818 0.182 0.000
B25-B34 Other viral diseases
0.817 0.183 0.000
I12.0 Hypertensive renal disease with renal failure
0.817 0.183 0.000
I45 Other conduction disorders
0.817 0.183 0.000
K22.7 Barrett's oesophagus
0.816 0.184 0.000
E20-E35 Disorders of other endocrine glands
0.813 0.187 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.813 0.187 0.000
K29.0 Acute haemorrhagic gastritis
0.813 0.187 0.000
Z96 Presence of other functional implants
0.808 0.192 0.000
K75 Other inflammatory liver diseases
0.808 0.192 0.000
B35-B49 Mycoses
0.807 0.193 0.000
K22.8 Other specified diseases of oesophagus
0.807 0.193 0.000
C15-C26 Malignant neoplasms of digestive organs
0.807 0.193 0.000
I62 Other nontraumatic intracranial haemorrhage
0.806 0.194 0.000
Z47 Other orthopaedic follow-up care
0.805 0.195 0.000
I33 Acute and subacute endocarditis
0.804 0.196 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.803 0.197 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.801 0.199 0.000
I47.1 Supraventricular tachycardia
0.800 0.200 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.800 0.200 0.000
M50-M54 Other dorsopathies
0.800 0.200 0.000
I67 Other cerebrovascular diseases
0.799 0.201 0.000
S10-S19 Injuries to the neck
0.799 0.201 0.000
G90-G99 Other disorders of the nervous system
0.798 0.202 0.000
J00-J06 Acute upper respiratory infections
0.797 0.203 0.000
N30.9 Cystitis, unspecified
0.797 0.203 0.000
S50-S59 Injuries to the elbow and forearm
0.796 0.204 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.796 0.204 0.000
Z95.4 Presence of other heart-valve replacement
0.795 0.205 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.795 0.205 0.000
Chapter XXII Codes for special purposes
0.792 0.208 0.000
R47-R49 Symptoms and signs involving speech and voice
0.790 0.210 0.000
F30-F39 Mood [affective] disorders
0.790 0.210 0.000
B15-B19 Viral hepatitis
0.789 0.210 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.789 0.211 0.000
E83.5 Disorders of calcium metabolism
0.788 0.212 0.000
K76 Other diseases of liver
0.788 0.212 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.787 0.213 0.000
J20-J22 Other acute lower respiratory infections
0.787 0.213 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.785 0.215 0.000
E87.7 Fluid overload
0.784 0.216 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.781 0.219 0.000
R68 Other general symptoms and signs
0.779 0.221 0.000
Z57 Occupational exposure to risk-factors
0.778 0.221 0.000
S40-S49 Injuries to the shoulder and upper arm
0.778 0.222 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.778 0.222 0.000
Z04.3 Examination and observation following other accident
0.778 0.222 0.000
J90-J94 Other diseases of pleura
0.777 0.223 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.777 0.223 0.000
Z99.2 Dependence on renal dialysis
0.776 0.224 0.000
K22.5 Diverticulum of oesophagus, acquired
0.775 0.225 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.775 0.225 0.000
Z04.9 Examination and observation for unspecified reason
0.774 0.226 0.000
C73 Malignant neoplasm of thyroid gland
0.774 0.226 0.000
R73.9 Hyperglycaemia, unspecified
0.773 0.227 0.000
J84 Other interstitial pulmonary diseases
0.772 0.228 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.771 0.229 0.000
K81 Cholecystitis
0.771 0.229 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.771 0.229 0.000
I49 Other cardiac arrhythmias
0.771 0.229 0.000
Z13.1 Special screening examination for diabetes mellitus
0.770 0.230 0.000
D26 Other benign neoplasms of uterus
0.769 0.231 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.769 0.231 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.768 0.232 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.767 0.233 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.767 0.233 0.000
K22.0 Achalasia of cardia
0.767 0.233 0.000
D17 Benign lipomatous neoplasm
0.766 0.234 0.000
M50 Cervical disk disorders
0.766 0.234 0.000
Z96.0 Presence of urogenital implants
0.766 0.234 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.766 0.234 0.000
K70 Alcoholic liver disease
0.765 0.235 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.765 0.235 0.000
K22.4 Dyskinesia of oesophagus
0.765 0.235 0.000
I63 Cerebral infarction
0.764 0.236 0.000
Z83 Family history of other specific disorders
0.764 0.236 0.000
N18.5 Chronic kidney disease, stage 5
0.762 0.238 0.000
F10.2 Dependence syndrome
0.762 0.238 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.762 0.238 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.762 0.238 0.000
A04 Other bacterial intestinal infections
0.761 0.239 0.000
E87.0 Hyperosmolality and hypernatraemia
0.761 0.239 0.000
D00-D09 In situ neoplasms
0.760 0.240 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.757 0.243 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.755 0.245 0.000
R60 Oedema, not elsewhere classified
0.755 0.245 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.754 0.246 0.000
Z02.8 Other examinations for administrative purposes
0.753 0.247 0.000
A41.8 Other specified septicaemia
0.752 0.248 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.752 0.248 0.000
K66 Other disorders of peritoneum
0.751 0.248 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.751 0.249 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.750 0.250 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.750 0.250 0.000
D34 Benign neoplasm of thyroid gland
0.750 0.250 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.749 0.251 0.000
Z53.0 Procedure not carried out because of contraindication
0.749 0.251 0.000
Z04.8 Examination and observation for other specified reasons
0.749 0.251 0.000
R63 Symptoms and signs concerning food and fluid intake
0.748 0.252 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.748 0.252 0.000
R25 Abnormal involuntary movements
0.748 0.252 0.000
K14 Diseases of tongue
0.747 0.253 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.747 0.253 0.000
I51 Complications and ill-defined descriptions of heart disease
0.746 0.254 0.000
M20-M25 Other joint disorders
0.746 0.254 0.000
K52 Other non-infective gastro-enteritis and colitis
0.746 0.254 0.000
T86 Failure and rejection of transplanted organs and tissues
0.745 0.255 0.000
J34 Other disorders of nose and nasal sinuses
0.744 0.256 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.743 0.257 0.000
Z49 Care involving dialysis
0.741 0.258 0.000
A49 Bacterial infection of unspecified site
0.741 0.259 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.740 0.260 0.000
C50.3 Lower-inner quadrant of breast
0.739 0.261 0.000
K05 Gingivitis and periodontal diseases
0.739 0.261 0.000
K27 Peptic ulcer, site unspecified
0.739 0.261 0.000
Z48.8 Other specified surgical follow-up care
0.739 0.261 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.738 0.262 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.737 0.263 0.000
K72 Hepatic failure, not elsewhere classified
0.737 0.263 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.736 0.264 0.000
I35.0 Aortic (valve) stenosis
0.735 0.265 0.000
S70-S79 Injuries to the hip and thigh
0.735 0.265 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.735 0.265 0.000
Z04.1 Examination and observation following transport accident
0.734 0.266 0.000
I20 Angina pectoris
0.731 0.269 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.731 0.269 0.000
K76.8 Other specified diseases of liver
0.731 0.269 0.000
G70-G73 Diseases of myoneural junction and muscle
0.730 0.270 0.000
C16 Malignant neoplasm of stomach
0.729 0.271 0.000
J38.3 Other diseases of vocal cords
0.728 0.272 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.728 0.272 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.728 0.272 0.000
K74.6 Other and unspecified cirrhosis of liver
0.727 0.273 0.000
C50.1 Central portion of breast
0.727 0.273 0.000
N17.8 Other acute renal failure
0.726 0.274 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.726 0.274 0.000
Z99.8 Dependence on other enabling machines and devices
0.725 0.274 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.725 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.725 0.275 0.000
I34.1 Mitral (valve) prolapse
0.725 0.275 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.724 0.276 0.000
E04 Other non-toxic goitre
0.723 0.277 0.000
Z58 Problems related to physical environment
0.722 0.278 0.000
K81.1 Chronic cholecystitis
0.722 0.278 0.000
T79-T79 Certain early complications of trauma
0.722 0.278 0.000
Z54 Convalescence
0.721 0.279 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.721 0.279 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.720 0.280 0.000
T39.1 4-Aminophenol derivatives
0.720 0.280 0.000
I42 Cardiomyopathy
0.719 0.281 0.000
Z50.1 Other physical therapy
0.719 0.281 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.718 0.281 0.000
J35 Chronic diseases of tonsils and adenoids
0.718 0.282 0.000
T90 Sequelae of injuries of head
0.718 0.282 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
Z03.8 Observation for other suspected diseases and conditions
0.716 0.284 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.716 0.284 0.000
R79.0 Abnormal level of blood mineral
0.715 0.284 0.000
K22.2 Oesophageal obstruction
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I30 Acute pericarditis
0.715 0.285 0.000
K22.3 Perforation of oesophagus
0.715 0.285 0.000
K11 Diseases of salivary glands
0.715 0.285 0.000
Z39 Postpartum care and examination
0.715 0.285 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.714 0.286 0.000
E88 Other metabolic disorders
0.714 0.286 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.714 0.286 0.000
E67 Other hyperalimentation
0.713 0.287 0.000
E68 Sequelae of hyperalimentation
0.713 0.287 0.000
E65 Localised adiposity
0.713 0.287 0.000
J39 Other diseases of upper respiratory tract
0.713 0.287 0.000
Z50.8 Care involving use of rehabilitation procedures
0.713 0.287 0.000
I24 Other acute ischaemic heart diseases
0.713 0.287 0.000
Z60 Problems related to social environment
0.713 0.287 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E73 Lactose intolerance
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
J80 Adult respiratory distress syndrome
0.712 0.288 0.000
J09-J18 Influenza and pneumonia
0.712 0.288 0.000
R61 Hyperhidrosis
0.711 0.289 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.711 0.289 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.711 0.289 0.000
E66.1 Drug-induced obesity
0.711 0.289 0.000
E66.0 Obesity due to excess calories
0.711 0.289 0.000
N30.0 Acute cystitis
0.711 0.289 0.000
Z89 Acquired absence of limb
0.710 0.290 0.000
Z84 Family history of other conditions
0.710 0.290 0.000
Z81 Family history of mental and behavioural disorders
0.710 0.290 0.000
Z36.9 Antenatal screening, unspecified
0.710 0.290 0.000
B07 Viral warts
0.709 0.291 0.000
Z10 Routine general health check-up of defined subpopulation
0.709 0.291 0.000
T33-T35 Frostbite
0.708 0.291 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.291 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.291 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.708 0.291 0.000
T00-T07 Injuries involving multiple body regions
0.708 0.291 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.708 0.291 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.708 0.292 0.000
I20.9 Angina pectoris, unspecified
0.708 0.292 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.294 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.706 0.294 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.706 0.294 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.706 0.294 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.706 0.294 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.706 0.294 0.000
Z94.0 Kidney transplant status
0.706 0.294 0.000
F80-F89 Disorders of psychological development
0.705 0.294 0.000
S60-S69 Injuries to the wrist and hand
0.705 0.295 0.000
C50.4 Upper-outer quadrant of breast
0.704 0.296 0.000
E27 Other disorders of adrenal gland
0.704 0.296 0.000
T93.1 Sequelae of fracture of femur
0.704 0.296 0.000
E87.4 Mixed disorder of acid-base balance
0.703 0.297 0.000
E87.3 Alkalosis
0.703 0.297 0.000
D35.2 Pituitary gland
0.703 0.297 0.000
I44 Atrioventricular and left bundle-branch block
0.703 0.297 0.000
M05-M14 Inflammatory polyarthropathies
0.703 0.297 0.000
Z36.8 Other antenatal screening
0.703 0.297 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.702 0.297 0.000
J95-J99 Other diseases of the respiratory system
0.702 0.298 0.000
A07 Other protozoal intestinal diseases
0.702 0.298 0.000
A06 Amoebiasis
0.702 0.298 0.000
A05 Other bacterial foodborne intoxications
0.702 0.298 0.000
A03 Shigellosis
0.702 0.298 0.000
A02 Other Salmonella infections
0.702 0.298 0.000
A01 Typhoid and paratyphoid fevers
0.702 0.298 0.000
A00 Cholera
0.702 0.298 0.000
J34.2 Deviated nasal septum
0.701 0.299 0.000
D60-D64 Aplastic and other anaemias
0.700 0.300 0.000
R52 Pain, not elsewhere classified
0.699 0.301 0.000
N18.2 Chronic kidney disease, stage 2
0.699 0.301 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.699 0.301 0.000
Z52 Donors of organs and tissues
0.699 0.301 0.000
M86-M90 Other osteopathies
0.699 0.301 0.000
K90-K93 Other diseases of the digestive system
0.699 0.301 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.698 0.302 0.000
K12 Stomatitis and related lesions
0.698 0.302 0.000
N18.8 Other chronic renal failure
0.697 0.302 0.000
N18.1 Chronic kidney disease, stage 1
0.697 0.302 0.000
Z43 Attention to artificial openings
0.697 0.303 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.696 0.304 0.000
J92 Pleural plaque
0.694 0.306 0.000
I38 Endocarditis, valve unspecified
0.693 0.307 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.693 0.307 0.000
K77 Liver disorders in diseases classified elsewhere
0.693 0.307 0.000
K73 Chronic hepatitis, not elsewhere classified
0.693 0.307 0.000
K71 Toxic liver disease
0.693 0.307 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.693 0.307 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.692 0.307 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.692 0.307 0.000
Q50-Q56 Congenital malformations of genital organs
0.692 0.308 0.000
A48 Other bacterial diseases, not elsewhere classified
0.691 0.309 0.000
A44 Bartonellosis
0.691 0.309 0.000
A43 Nocardiosis
0.691 0.309 0.000
A42 Actinomycosis
0.691 0.309 0.000
A40 Streptococcal septicaemia
0.691 0.309 0.000
A39 Meningococcal infection
0.691 0.309 0.000
A37 Whooping cough
0.691 0.309 0.000
A36 Diphtheria
0.691 0.309 0.000
A32 Listeriosis
0.691 0.309 0.000
A31 Infection due to other mycobacteria
0.691 0.309 0.000
A30 Leprosy [Hansen's disease]
0.691 0.309 0.000
A46 Erysipelas
0.691 0.309 0.000
A38 Scarlet fever
0.691 0.309 0.000
A35 Other tetanus
0.691 0.309 0.000
A34 Obstetrical tetanus
0.691 0.309 0.000
A33 Tetanus neonatorum
0.691 0.309 0.000
R76 Other abnormal immunological findings in serum
0.691 0.309 0.000
K29.4 Chronic atrophic gastritis
0.691 0.309 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.691 0.309 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.691 0.309 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.691 0.309 0.000
I60 Subarachnoid haemorrhage
0.690 0.310 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.690 0.310 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.690 0.310 0.000
K25.3 Acute without haemorrhage or perforation
0.690 0.310 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.689 0.311 0.000
Z44 Fitting and adjustment of external prosthetic device
0.689 0.311 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.689 0.311 0.000
Z92 Personal history of medical treatment
0.688 0.312 0.000
K86 Other diseases of pancreas
0.688 0.312 0.000
Z12 Special screening examination for neoplasms
0.688 0.312 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.687 0.312 0.000
R77 Other abnormalities of plasma proteins
0.687 0.312 0.000
R74 Abnormal serum enzyme levels
0.687 0.312 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.687 0.312 0.000
R71 Abnormality of red blood cells
0.687 0.312 0.000
K10 Other diseases of jaws
0.687 0.313 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.687 0.313 0.000
Z34 Supervision of normal pregnancy
0.686 0.314 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.685 0.315 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.685 0.315 0.000
E87.6 Hypokalaemia
0.684 0.316 0.000
F10.1 Harmful use
0.684 0.316 0.000
I67.8 Other specified cerebrovascular diseases
0.684 0.316 0.000
K66.0 Peritoneal adhesions
0.684 0.316 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.683 0.316 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.682 0.318 0.000
K74.0 Hepatic fibrosis
0.682 0.318 0.000
D10 Benign neoplasm of mouth and pharynx
0.682 0.318 0.000
I15 Secondary hypertension
0.681 0.318 0.000
I13 Hypertensive heart and renal disease
0.681 0.318 0.000
I11 Hypertensive heart disease
0.681 0.318 0.000
E83.4 Disorders of magnesium metabolism
0.681 0.319 0.000
K29.9 Gastroduodenitis, unspecified
0.681 0.319 0.000
K29.3 Chronic superficial gastritis
0.681 0.319 0.000
K29.2 Alcoholic gastritis
0.681 0.319 0.000
N00-N08 Glomerular diseases
0.681 0.319 0.000
D11 Benign neoplasm of major salivary glands
0.680 0.320 0.000
K09 Cysts of oral region, not elsewhere classified
0.680 0.320 0.000
M50.2 Other cervical disk displacement
0.680 0.320 0.000
Z97 Presence of other devices
0.680 0.320 0.000
Z95.3 Presence of xenogenic heart valve
0.679 0.321 0.000
T87 Complications peculiar to reattachment and amputation
0.679 0.321 0.000
D31 Benign neoplasm of eye and adnexa
0.678 0.321 0.000
D30 Benign neoplasm of urinary organs
0.678 0.321 0.000
D29 Benign neoplasm of male genital organs
0.678 0.321 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.678 0.321 0.000
D19 Benign neoplasm of mesothelial tissue
0.678 0.321 0.000
D16 Benign neoplasm of bone and articular cartilage
0.678 0.321 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.678 0.321 0.000
F60-F69 Disorders of adult personality and behaviour
0.677 0.322 0.000
K29.5 Chronic gastritis, unspecified
0.678 0.322 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.676 0.324 0.000
F70-F79 Mental retardation
0.676 0.324 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.676 0.324 0.000
D12.6 Colon, unspecified
0.676 0.324 0.000
K07 Dentofacial anomalies [including malocclusion]
0.676 0.324 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.676 0.324 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.675 0.325 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.675 0.325 0.000
Z13.5 Special screening examination for eye and ear disorders
0.675 0.325 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.675 0.325 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.675 0.325 0.000
Z13.2 Special screening examination for nutritional disorders
0.675 0.325 0.000
I45.5 Other specified heart block
0.674 0.326 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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