TreeWAS – Variant ID: rs11825064

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D86 Sarcoidosis	0.252	0.748	0.000
D86.0 Sarcoidosis of lung	0.248	0.752	0.000
D86.9 Sarcoidosis, unspecified	0.248	0.752	0.000
D86.8 Sarcoidosis of other and combined sites	0.234	0.765	0.000
D86.1 Sarcoidosis of lymph nodes	0.205	0.795	0.000
D86.3 Sarcoidosis of skin	0.181	0.819	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.181	0.819	0.000
D80-D89 Certain disorders involving the immune mechanism	0.154	0.846	0.000
D80 Immunodeficiency with predominantly antibody defects	0.120	0.880	0.000
D84 Other immunodeficiencies	0.114	0.886	0.000
D83 Common variable immunodeficiency	0.113	0.887	0.000
D82 Immunodeficiency associated with other major defects	0.110	0.890	0.000
D81 Combined immunodeficiencies	0.110	0.890	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.095	0.905	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.094	0.906	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.091	0.909	0.000
D84.1 Defects in the complement system	0.087	0.913	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.086	0.914	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.086	0.914	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.086	0.914	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.086	0.914	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.086	0.914	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.086	0.914	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.086	0.914	0.000
D83.9 Common variable immunodeficiency, unspecified	0.083	0.916	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.082	0.918	0.000
D84.8 Other specified immunodeficiencies	0.082	0.918	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.082	0.918	0.000
D83.8 Other common variable immunodeficiencies	0.081	0.919	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.081	0.919	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.081	0.919	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.081	0.919	0.000
D84.9 Immunodeficiency, unspecified	0.080	0.920	0.000
D81.9 Combined immunodeficiency, unspecified	0.079	0.921	0.000
D81.8 Other combined immunodeficiencies	0.079	0.921	0.000
D81.7 Major histocompatibility complex class II deficiency	0.079	0.921	0.000
D81.6 Major histocompatibility complex class I deficiency	0.079	0.921	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.079	0.921	0.000
D81.4 Nezelof's syndrome	0.079	0.921	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.079	0.921	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.079	0.921	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.079	0.921	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.079	0.921	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.079	0.921	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.079	0.921	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.079	0.921	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.079	0.921	0.000
D82.2 Immunodeficiency with short-limbed stature	0.079	0.921	0.000
D82.1 Di George's syndrome	0.079	0.921	0.000
D82.0 Wiskott-Aldrich syndrome	0.079	0.921	0.000
E10.3 With ophthalmic complications	0.079	0.921	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.079	0.921	0.000
D60-D64 Aplastic and other anaemias	0.078	0.922	0.000
D62 Acute posthaemorrhagic anaemia	0.077	0.923	0.000
E10 Insulin-dependent diabetes mellitus	0.077	0.923	0.000
E10.4 With neurological complications	0.075	0.925	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.071	0.929	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.068	0.932	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.067	0.932	0.000
D89.3 Immune reconstitution syndrome	0.067	0.932	0.000
D89.1 Cryoglobulinaemia	0.067	0.932	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.067	0.932	0.000
D55-D59 Haemolytic anaemias	0.066	0.934	0.000
E10.2 With renal complications	0.065	0.935	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.064	0.936	0.000
E10.5 With peripheral circulatory complications	0.063	0.937	0.000
D63.0 Anaemia in neoplastic disease	0.059	0.941	0.000
E10.0 With coma	0.058	0.942	0.000
E10.8 With unspecified complications	0.056	0.944	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.056	0.944	0.000
E10.7 With multiple complications	0.055	0.945	0.000
D59 Acquired haemolytic anaemia	0.054	0.946	0.000
D56 Thalassaemia	0.052	0.947	0.000
E10.6 With other specified complications	0.051	0.948	0.000
E10.9 Without complications	0.052	0.948	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.051	0.949	0.000
D61 Other aplastic anaemias	0.051	0.949	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.050	0.950	0.000
D57 Sickle-cell disorders	0.047	0.953	0.000
D55 Anaemia due to enzyme disorders	0.047	0.953	0.000
D50-D53 Nutritional anaemias	0.047	0.953	0.000
D58 Other hereditary haemolytic anaemias	0.046	0.954	0.000
E10-E14 Diabetes mellitus	0.045	0.955	0.000
E10.1 With ketoacidosis	0.045	0.955	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.044	0.956	0.000
D56.1 Beta thalassaemia	0.041	0.959	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.040	0.960	0.000
D60.8 Other acquired pure red cell aplasias	0.040	0.960	0.000
D60.1 Transient acquired pure red cell aplasia	0.040	0.960	0.000
D60.0 Chronic acquired pure red cell aplasia	0.040	0.960	0.000
D56.3 Thalassaemia trait	0.040	0.960	0.000
D61.1 Drug-induced aplastic anaemia	0.040	0.960	0.000
D59.1 Other autoimmune haemolytic anaemias	0.040	0.960	0.000
E11 Non-insulin-dependent diabetes mellitus	0.040	0.960	0.000
D59.8 Other acquired haemolytic anaemias	0.039	0.961	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.039	0.961	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.039	0.961	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.039	0.961	0.000
D59.3 Haemolytic-uraemic syndrome	0.039	0.961	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.039	0.961	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.039	0.961	0.000
E11.5 With peripheral circulatory complications	0.039	0.961	0.000
D56.9 Thalassaemia, unspecified	0.038	0.962	0.000
D56.8 Other thalassaemias	0.038	0.962	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.038	0.962	0.000
D56.2 Delta-beta thalassaemia	0.038	0.962	0.000
D56.0 Alpha thalassaemia	0.038	0.962	0.000
E11.8 With unspecified complications	0.037	0.963	0.000
D61.8 Other specified aplastic anaemias	0.037	0.963	0.000
D61.3 Idiopathic aplastic anaemia	0.037	0.963	0.000
D61.2 Aplastic anaemia due to other external agents	0.037	0.963	0.000
D61.0 Constitutional aplastic anaemia	0.037	0.963	0.000
E14 Unspecified diabetes mellitus	0.036	0.964	0.000
D50 Iron deficiency anaemia	0.035	0.965	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.034	0.966	0.000
D55.8 Other anaemias due to enzyme disorders	0.034	0.966	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.034	0.966	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.034	0.966	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.034	0.966	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.034	0.966	0.000
D57.8 Other sickle-cell disorders	0.034	0.966	0.000
D57.3 Sickle-cell trait	0.034	0.966	0.000
D57.2 Double heterozygous sickling disorders	0.034	0.966	0.000
D57.1 Sickle-cell anaemia without crisis	0.034	0.966	0.000
D57.0 Sickle-cell anaemia with crisis	0.034	0.966	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.033	0.967	0.000
D58.2 Other haemoglobinopathies	0.033	0.967	0.000
D58.1 Hereditary elliptocytosis	0.033	0.967	0.000
D58.0 Hereditary spherocytosis	0.033	0.967	0.000
E12 Malnutrition-related diabetes mellitus	0.033	0.967	0.000
D64 Other anaemias	0.033	0.967	0.000
D50.9 Iron deficiency anaemia, unspecified	0.033	0.967	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.032	0.967	0.000
D53 Other nutritional anaemias	0.032	0.968	0.000
E14.3 With ophthalmic complications	0.031	0.969	0.000
D51 Vitamin B12 deficiency anaemia	0.031	0.969	0.000
E11.1 With ketoacidosis	0.029	0.971	0.000
E14.6 With other specified complications	0.029	0.971	0.000
E14.4 With neurological complications	0.029	0.971	0.000
E11.7 With multiple complications	0.029	0.971	0.000
E11.3 With ophthalmic complications	0.029	0.971	0.000
E11.2 With renal complications	0.029	0.971	0.000
E11.6 With other specified complications	0.028	0.972	0.000
D52 Folate deficiency anaemia	0.028	0.972	0.000
D61.9 Aplastic anaemia, unspecified	0.027	0.972	0.000
E14.2 Withrenal complications	0.027	0.973	0.000
E14.8 With unspecified complications	0.026	0.974	0.000
E14.7 With multiple complications	0.026	0.974	0.000
E14.5 With peripheral circulatory complications	0.026	0.974	0.000
E14.1 With ketoacidosis	0.026	0.974	0.000
E14.0 With coma	0.026	0.974	0.000
E13 Other specified diabetes mellitus	0.025	0.974	0.000
D50.1 Sideropenic dysphagia	0.025	0.974	0.000
E11.4 With neurological complications	0.025	0.975	0.000
E11.0 With coma	0.024	0.976	0.000
E12.9 Without complications	0.024	0.976	0.000
E12.8 With unspecified complications	0.024	0.976	0.000
E12.7 With multiple complications	0.024	0.976	0.000
E12.6 With other specified complications	0.024	0.976	0.000
E12.5 With peripheral circulatory complications	0.024	0.976	0.000
E12.4 With neurological complications	0.024	0.976	0.000
E12.3 With ophthalmic complications	0.024	0.976	0.000
E12.2 With renal complications	0.024	0.976	0.000
E12.1 With ketoacidosis	0.024	0.976	0.000
E12.0 With coma	0.024	0.976	0.000
D64.4 Congenital dyserythropoietic anaemia	0.024	0.976	0.000
D64.3 Other sideroblastic anaemias	0.024	0.976	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.024	0.976	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.024	0.976	0.000
D64.0 Hereditary sideroblastic anaemia	0.024	0.976	0.000
D53.8 Other specified nutritional anaemias	0.023	0.976	0.000
D53.2 Scorbutic anaemia	0.023	0.976	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.023	0.976	0.000
D53.0 Protein deficiency anaemia	0.023	0.976	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.022	0.978	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.022	0.978	0.000
D51.2 Transcobalamin II deficiency	0.022	0.978	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.022	0.978	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.022	0.978	0.000
D53.9 Nutritional anaemia, unspecified	0.022	0.978	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.021	0.978	0.000
D64.8 Other specified anaemias	0.021	0.979	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.021	0.979	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.020	0.980	0.000
D52.8 Other folate deficiency anaemias	0.020	0.980	0.000
D52.1 Drug-induced folate deficiency anaemia	0.020	0.980	0.000
D52.0 Dietary folate deficiency anaemia	0.020	0.980	0.000
E13.8 With unspecified complications	0.018	0.981	0.000
E13.7 With multiple complications	0.018	0.981	0.000
E13.6 With other specified complications	0.018	0.981	0.000
E13.5 With peripheral circulatory complications	0.018	0.981	0.000
E13.4 With neurological complications	0.018	0.981	0.000
E13.3 With ophthalmic complications	0.018	0.981	0.000
E13.2 With renal complications	0.018	0.981	0.000
E13.1 With ketoacidosis	0.018	0.981	0.000
E13.0 With coma	0.018	0.981	0.000
D50.8 Other iron deficiency anaemias	0.018	0.982	0.000
D67 Hereditary factor IX deficiency	0.016	0.984	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.016	0.984	0.000
R76 Other abnormal immunological findings in serum	0.016	0.984	0.000
R73 Elevated blood glucose level	0.015	0.985	0.000
R73.9 Hyperglycaemia, unspecified	0.015	0.985	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.015	0.985	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.015	0.985	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.015	0.985	0.000
R79 Other abnormal findings of blood chemistry	0.015	0.985	0.000
R76.8 Other specified abnormal immunological findings in serum	0.014	0.986	0.000
C25.0 Head of pancreas	0.000	0.986	0.014
D52.9 Folate deficiency anaemia, unspecified	0.014	0.986	0.000
D66 Hereditary factor VIII deficiency	0.014	0.986	0.000
R74 Abnormal serum enzyme levels	0.014	0.986	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.014	0.986	0.000
R76.0 Raised antibody titer	0.014	0.986	0.000
R79.0 Abnormal level of blood mineral	0.013	0.986	0.000
C25.9 Pancreas, unspecified	0.000	0.987	0.013
C25 Malignant neoplasm of pancreas	0.000	0.987	0.013
R78 Findings of drugs and other substances, not normally found in blood	0.012	0.988	0.000
R74.8 Abnormal levels of other serum enzymes	0.012	0.988	0.000
D75 Other diseases of blood and blood-forming organs	0.012	0.988	0.000
R71 Abnormality of red blood cells	0.012	0.988	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.012	0.988	0.000
E13.9 Without complications	0.011	0.988	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.011	0.989	0.000
R76.2 False-positive serological test for syphilis	0.011	0.989	0.000
R76.1 Abnormal reaction to tuberculin test	0.011	0.989	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.011	0.989	0.000
D74 Methaemoglobinaemia	0.011	0.989	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.011	0.989	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.011	0.989	0.000
R73.0 Abnormal glucose tolerance test	0.011	0.989	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.000	0.989	0.011
C25.2 Tail of pancreas	0.000	0.989	0.011
C25.1 Body of pancreas	0.000	0.990	0.010
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.010	0.990	0.000
D75.1 Secondary polycythaemia	0.010	0.990	0.000
O04.9 Complete or unspecified, without complication	0.010	0.990	0.000
E14.9 Without complications	0.010	0.990	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.010	0.990	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.010	0.990	0.000
R77 Other abnormalities of plasma proteins	0.010	0.990	0.000
R78.0 Finding of alcohol in blood	0.010	0.990	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.010	0.990	0.000
D75.0 Familial erythrocytosis	0.010	0.990	0.000
D68 Other coagulation defects	0.010	0.990	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.991	0.009
C25.7 Other parts of pancreas	0.000	0.991	0.009
D72 Other disorders of white blood cells	0.009	0.991	0.000
D69 Purpura and other haemorrhagic conditions	0.009	0.991	0.000
D75.2 Essential thrombocytosis	0.009	0.991	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.009	0.991	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.009	0.991	0.000
R78.6 Finding of steroid agent in blood	0.009	0.991	0.000
R78.5 Finding of psychotropic drug in blood	0.009	0.991	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.009	0.991	0.000
R78.3 Finding of hallucinogen in blood	0.009	0.991	0.000
R78.2 Finding of cocaine in blood	0.009	0.991	0.000
R78.1 Finding of opiate drug in blood	0.009	0.991	0.000
R70.1 Abnormal plasma viscosity	0.009	0.991	0.000
C25.3 Pancreatic duct	0.000	0.991	0.009
R78.8 Finding of other specified substances, not normally found in blood	0.009	0.991	0.000
D68.5 Primary Thrombophilia	0.008	0.991	0.000
D69.2 Other nonthrombocytopenic purpura	0.008	0.991	0.000
D74.9 Methaemoglobinaemia, unspecified	0.008	0.992	0.000
D74.8 Other methaemoglobinaemias	0.008	0.992	0.000
D74.0 Congenital methaemoglobinaemia	0.008	0.992	0.000
C25.4 Endocrine pancreas	0.000	0.992	0.008
D76.2 Haemophagocytic syndrome, infection-associated	0.007	0.992	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.007	0.992	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.007	0.992	0.000
R77.1 Abnormality of globulin	0.007	0.992	0.000
D64.9 Anaemia, unspecified	0.008	0.992	0.000
R77.2 Abnormality of alphafetoprotein	0.007	0.993	0.000
R77.0 Abnormality of albumin	0.007	0.993	0.000
D72.1 Eosinophilia	0.007	0.993	0.000
D68.1 Hereditary factor XI deficiency	0.007	0.993	0.000
D68.4 Acquired coagulation factor deficiency	0.007	0.993	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.007	0.993	0.000
D72.9 Disorder of white blood cells, unspecified	0.007	0.993	0.000
D72.0 Genetic anomalies of leukocytes	0.007	0.993	0.000
D69.4 Other primary thrombocytopenia	0.007	0.993	0.000
D68.9 Coagulation defect, unspecified	0.007	0.993	0.000
D68.6 Other Thrombophilia	0.007	0.993	0.000
D69.8 Other specified haemorrhagic conditions	0.007	0.993	0.000
D69.1 Qualitative platelet defects	0.007	0.993	0.000
D76.3 Other histiocytosis syndromes	0.007	0.993	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.007	0.993	0.000
D69.0 Allergic purpura	0.007	0.993	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.993	0.007
R77.9 Abnormality of plasma protein, unspecified	0.006	0.993	0.000
I07.1 Tricuspid insufficiency	0.007	0.993	0.000
C18.4 Transverse colon	0.000	0.994	0.006
D68.0 Von Willebrand's disease	0.006	0.994	0.000
D69.9 Haemorrhagic condition, unspecified	0.006	0.994	0.000
R77.8 Other specified abnormalities of plasma proteins	0.006	0.994	0.000
D69.5 Secondary thrombocytopenia	0.006	0.994	0.000
C18 Malignant neoplasm of colon	0.000	0.994	0.006
I73.0 Raynaud's syndrome	0.000	0.994	0.006
D68.8 Other specified coagulation defects	0.006	0.994	0.000
C18.6 Descending colon	0.000	0.994	0.006
T78.2 Anaphylactic shock, unspecified	0.006	0.994	0.000
T78 Adverse effects, not elsewhere classified	0.006	0.994	0.000
J38.3 Other diseases of vocal cords	0.000	0.994	0.006
C18.0 Caecum	0.000	0.994	0.006
C18.3 Hepatic flexure	0.000	0.994	0.005
I07 Rheumatic tricuspid valve diseases	0.005	0.994	0.000
C18.9 Colon, unspecified	0.000	0.995	0.005
D75.9 Disease of blood and blood-forming organs, unspecified	0.005	0.995	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.005	0.995	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.005	0.995	0.000
J38.7 Other diseases of larynx	0.000	0.995	0.005
T78.3 Angioneurotic oedema	0.005	0.995	0.000
D73 Diseases of spleen	0.005	0.995	0.001
S72.00 Fracture of neck of femur (closed)	0.000	0.995	0.005
C18.8 Overlapping lesion of colon	0.000	0.995	0.005
T78.8 Other adverse effects, not elsewhere classified	0.005	0.995	0.000
C18.1 Appendix	0.000	0.995	0.005
O63.0 Prolonged first stage (of labour)	0.005	0.995	0.000
D72.8 Other specified disorders of white blood cells	0.005	0.995	0.000
I08.0 Disorders of both mitral and aortic valves	0.005	0.995	0.000
D68.2 Hereditary deficiency of other clotting factors	0.005	0.995	0.000
I05-I09 Chronic rheumatic heart diseases	0.005	0.995	0.000
I08 Multiple valve diseases	0.005	0.995	0.000
L81.4 Other melanin hyperpigmentation	0.005	0.995	0.000
C18.7 Sigmoid colon	0.000	0.995	0.005
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.004	0.995	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.995	0.005
Z50.1 Other physical therapy	0.000	0.995	0.005
T78.9 Adverse effect, unspecified	0.004	0.996	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.004	0.996	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.996	0.004
I09 Other rheumatic heart diseases	0.004	0.996	0.000
C18.2 Ascending colon	0.000	0.996	0.004
O04 Medical abortion	0.004	0.996	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.004	0.996	0.000
I07.9 Tricuspid valve disease, unspecified	0.004	0.996	0.000
I07.8 Other tricuspid valve diseases	0.004	0.996	0.000
I07.2 Tricuspid stenosis with insufficiency	0.004	0.996	0.000
I07.0 Tricuspid stenosis	0.004	0.996	0.000
C18.5 Splenic flexure	0.000	0.996	0.004
D73.9 Disease of spleen, unspecified	0.003	0.996	0.001
D73.4 Cyst of spleen	0.003	0.996	0.001
D73.3 Abscess of spleen	0.003	0.996	0.001
D73.2 Chronic congestive splenomegaly	0.003	0.996	0.001
D73.1 Hypersplenism	0.003	0.996	0.001
I09.9 Rheumatic heart disease, unspecified	0.004	0.996	0.000
I06 Rheumatic aortic valve diseases	0.004	0.996	0.000
H34.8 Other retinal vascular occlusions	0.004	0.996	0.000
I05 Rheumatic mitral valve diseases	0.004	0.996	0.000
M75.1 Rotator cuff syndrome	0.000	0.996	0.004
R79.9 Abnormal finding of blood chemistry, unspecified	0.003	0.996	0.001
D73.8 Other diseases of spleen	0.003	0.996	0.001
J38.6 Stenosis of larynx	0.000	0.996	0.004
J38.2 Nodules of vocal cords	0.000	0.996	0.004
I05.1 Rheumatic mitral insufficiency	0.004	0.996	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.004	0.996	0.000
I08.9 Multiple valve disease, unspecified	0.003	0.996	0.000
X41.9 Unspecified place	0.003	0.997	0.000
G59.0 Diabetic mononeuropathy	0.003	0.997	0.000
I08.8 Other multiple valve diseases	0.003	0.997	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.997	0.003
I06.0 Rheumatic aortic stenosis	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
I09.8 Other specified rheumatic heart diseases	0.003	0.997	0.000
I09.2 Chronic rheumatic pericarditis	0.003	0.997	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.003	0.997	0.000
I09.0 Rheumatic myocarditis	0.003	0.997	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.003	0.997	0.000
O04.7 Complete or unspecified, complicated by embolism	0.003	0.997	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.003	0.997	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.003	0.997	0.000
O04.3 Incomplete, with other and unspecified complications	0.003	0.997	0.000
O04.2 Incomplete, complicated by embolism	0.003	0.997	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.003	0.997	0.000
Z50 Care involving use of rehabilitation procedures	0.000	0.997	0.003
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.997	0.003
R52.1 Chronic intractable pain	0.000	0.997	0.003
T78.4 Allergy, unspecified	0.003	0.997	0.000
N20.0 Calculus of kidney	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.003	0.997	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.003	0.997	0.000
I06.8 Other rheumatic aortic valve diseases	0.003	0.997	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.003	0.997	0.000
I06.1 Rheumatic aortic insufficiency	0.003	0.997	0.000
Z50.5 Speech therapy	0.000	0.997	0.003
I05.8 Other mitral valve diseases	0.003	0.997	0.000
O04.4 Incomplete, without complication	0.003	0.997	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.003	0.997	0.000
D73.5 Infarction of spleen	0.002	0.997	0.001
J38.4 Oedema of larynx	0.000	0.997	0.003
J38.5 Laryngeal spasm	0.000	0.997	0.003
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.997	0.003
S72.0 Fracture of neck of femur	0.000	0.997	0.003
C21 Malignant neoplasm of anus and anal canal	0.000	0.997	0.003
S52.60 Fracture of lower end of both ulna and radius (closed)	0.003	0.997	0.000
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
Z50.6 Orthoptic training	0.000	0.997	0.003
Z50.3 Drug rehabilitation	0.000	0.997	0.003
L81 Other disorders of pigmentation	0.003	0.997	0.000
I05.0 Mitral stenosis	0.002	0.997	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
E53.8 Deficiency of other specified B group vitamins	0.003	0.997	0.000
H34.2 Other retinal artery occlusions	0.003	0.997	0.000
Z50.2 Alcohol rehabilitation	0.000	0.997	0.003
C21.1 Anal canal	0.000	0.997	0.002
T14.0 Superficial injury of unspecified body region	0.003	0.997	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.997	0.002
L81.8 Other specified disorders of pigmentation	0.003	0.997	0.000
H34 Retinal vascular occlusions	0.003	0.997	0.000
C24.1 Ampulla of Vater	0.000	0.998	0.002
C23 Malignant neoplasm of gallbladder	0.000	0.998	0.002
L81.0 Postinflammatory hyperpigmentation	0.002	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.002	0.998	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.998	0.002
I84.5 External haemorrhoids without complication	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
F30.0 Hypomania	0.002	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.998	0.002
C24.8 Overlapping lesion of biliary tract	0.000	0.998	0.002
C24.0 Extrahepatic bile duct	0.000	0.998	0.002
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.998	0.002
C24.9 Biliary tract, unspecified	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.998	0.002
C21.2 Cloacogenic zone	0.000	0.998	0.002
L81.2 Freckles	0.002	0.998	0.000
O43.8 Other placental disorders	0.000	0.998	0.002
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
L81.7 Pigmented purpuric dermatosis	0.002	0.998	0.000
L81.6 Other disorders of diminished melanin formation	0.002	0.998	0.000
L81.5 Leukoderma, not elsewhere classified	0.002	0.998	0.000
L81.3 Cafe au lait spots	0.002	0.998	0.000
L81.1 Chloasma	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
X41.0 Home	0.002	0.998	0.000
X41.8 Other specified place	0.002	0.998	0.000
X41.7 Farm	0.002	0.998	0.000
X41.6 Industrial and construction area	0.002	0.998	0.000
X41.5 Trade and service area	0.002	0.998	0.000
X41.4 Street and highway	0.002	0.998	0.000
X41.3 Sports and athletics area	0.002	0.998	0.000
X41.2 School, other institution and public administrative area	0.002	0.998	0.000
X41.1 Residential institution	0.002	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.002	0.998	0.000
D35.0 Adrenal gland	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
H34.0 Transient retinal artery occlusion	0.002	0.998	0.000
X49.9 Unspecified place	0.002	0.998	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.998	0.002
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.998	0.002
C17 Malignant neoplasm of small intestine	0.000	0.998	0.002
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.002	0.998	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.998	0.002
I49.9 Cardiac arrhythmia, unspecified	0.002	0.998	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.002	0.998	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.002	0.998	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.002	0.998	0.000
D73.0 Hyposplenism	0.001	0.998	0.001
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
X47.0 Home	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.998	0.002
H34.1 Central retinal artery occlusion	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.998	0.002
F30 Manic episode	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
D37.7 Other digestive organs	0.000	0.998	0.002
Q76.0 Spina bifida occulta	0.002	0.998	0.000
T14 Injury of unspecified body region	0.002	0.998	0.000
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities	0.002	0.998	0.000
X47.9 Unspecified place	0.002	0.998	0.000
R52 Pain, not elsewhere classified	0.000	0.998	0.002
T71 Asphyxiation	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
H91.9 Hearing loss, unspecified	0.000	0.998	0.002
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
C17.0 Duodenum	0.000	0.998	0.002
T66 Unspecified effects of radiation	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.000	0.998	0.002
C17.3 Meckel's diverticulum	0.000	0.998	0.002
C26.8 Overlapping lesion of digestive system	0.000	0.998	0.001
C26.1 Spleen	0.000	0.998	0.001
E28.3 Primary ovarian failure	0.002	0.998	0.000
W13.9 Unspecified place	0.002	0.998	0.000
T70 Effects of air pressure and water pressure	0.002	0.998	0.000
T74 Maltreatment syndromes	0.002	0.998	0.000
T73 Effects of other deprivation	0.002	0.998	0.000
T69 Other effects of reduced temperature	0.002	0.998	0.000
T67 Effects of heat and light	0.002	0.998	0.000
N20 Calculus of kidney and ureter	0.002	0.998	0.000
C21.0 Anus, unspecified	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations