TreeWAS – Variant ID: rs11853441

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	0.996	0.004	0.000
I10 Essential (primary) hypertension	0.995	0.005	0.000
I10-I15 Hypertensive diseases	0.993	0.007	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.993	0.007	0.000
Chapter IX Diseases of the circulatory system	0.990	0.010	0.000
I20 Angina pectoris	0.983	0.017	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.980	0.020	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.958	0.042	0.000
I20.0 Unstable angina	0.945	0.055	0.000
I20.9 Angina pectoris, unspecified	0.943	0.057	0.000
I21.4 Acute subendocardial myocardial infarction	0.942	0.058	0.000
I22 Subsequent myocardial infarction	0.937	0.063	0.000
I24 Other acute ischaemic heart diseases	0.922	0.078	0.000
I15 Secondary hypertension	0.913	0.087	0.000
I25.5 Ischaemic cardiomyopathy	0.900	0.100	0.000
I24.8 Other forms of acute ischaemic heart disease	0.895	0.105	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.893	0.107	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.890	0.110	0.000
I27 Other pulmonary heart diseases	0.841	0.159	0.000
I15.1 Hypertension secondary to other renal disorders	0.829	0.171	0.000
I05-I09 Chronic rheumatic heart diseases	0.817	0.183	0.000
I22.8 Subsequent myocardial infarction of other sites	0.811	0.189	0.000
I25.4 Coronary artery aneurysm	0.809	0.191	0.000
I11 Hypertensive heart disease	0.809	0.191	0.000
I27.2 Other secondary pulmonary hypertension	0.797	0.203	0.000
I24.1 Dressler's syndrome	0.789	0.211	0.000
I20.1 Angina pectoris with documented spasm	0.784	0.216	0.000
I15.9 Seconday hypertension, unspecified	0.745	0.255	0.000
I25.6 Silent myocardial ischaemia	0.721	0.279	0.000
I00-I02 Acute rheumatic fever	0.720	0.280	0.000
I08 Multiple valve diseases	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.716	0.284	0.000
I27.8 Other specified pulmonary heart diseases	0.716	0.284	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.714	0.286	0.000
I13 Hypertensive heart and renal disease	0.712	0.288	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.703	0.297	0.000
I25.3 Aneurysm of heart	0.666	0.334	0.000
I26 Pulmonary embolism	0.664	0.336	0.000
I15.0 Renovascular hypertension	0.664	0.336	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.663	0.337	0.000
I15.8 Other secondary hypertension	0.659	0.341	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.651	0.349	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.647	0.353	0.000
I25.2 Old myocardial infarction	0.637	0.363	0.000
I77 Other disorders of arteries and arterioles	0.634	0.366	0.000
I15.2 Hypertension secondary to endocrine disorders	0.634	0.366	0.000
I09 Other rheumatic heart diseases	0.624	0.376	0.000
I05 Rheumatic mitral valve diseases	0.623	0.377	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.622	0.378	0.000
I27.0 Primary pulmonary hypertension	0.617	0.383	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.616	0.384	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.611	0.389	0.000
I08.0 Disorders of both mitral and aortic valves	0.607	0.393	0.000
I27.1 Kyphoscoliotic heart disease	0.603	0.397	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.597	0.403	0.000
I77.6 Arteritis, unspecified	0.588	0.412	0.000
I06 Rheumatic aortic valve diseases	0.586	0.414	0.000
I08.9 Multiple valve disease, unspecified	0.580	0.420	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.564	0.436	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.552	0.448	0.000
I99 Other and unspecified disorders of circulatory system	0.547	0.453	0.000
I21.9 Acute myocardial infarction, unspecified	0.542	0.458	0.000
I97.1 Other functional disturbances following cardiac surgery	0.541	0.459	0.000
I74 Arterial embolism and thrombosis	0.538	0.462	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.534	0.466	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.533	0.467	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.529	0.471	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.527	0.473	0.000
I00 Rheumatic fever without mention of heart involvement	0.527	0.473	0.000
I70 Atherosclerosis	0.519	0.481	0.000
I28 Other diseases of pulmonary vessels	0.518	0.482	0.000
I02 Rheumatic chorea	0.516	0.483	0.000
I01 Rheumatic fever with heart involvement	0.516	0.483	0.000
I05.0 Mitral stenosis	0.514	0.486	0.000
I77.2 Rupture of artery	0.514	0.486	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.514	0.486	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.514	0.486	0.000
I23.8 Other current complications following acute myocardial infarction	0.513	0.487	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.510	0.489	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.510	0.489	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.510	0.489	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.510	0.489	0.000
I97.0 Postcardiotomy syndrome	0.506	0.494	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.501	0.499	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.496	0.504	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.495	0.505	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.490	0.510	0.000
I09.9 Rheumatic heart disease, unspecified	0.485	0.515	0.000
I08.8 Other multiple valve diseases	0.483	0.517	0.000
I05.9 Mitral valve disease, unspecified	0.473	0.527	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.468	0.532	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.467	0.533	0.000
I77.3 Arterial fibromuscular dysplasia	0.458	0.542	0.000
I77.5 Necrosis of artery	0.455	0.545	0.000
I77.4 Coeliac artery compression syndrome	0.455	0.545	0.000
I70.1 Atherosclerosis of renal artery	0.451	0.548	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.450	0.550	0.000
I09.8 Other specified rheumatic heart diseases	0.447	0.552	0.000
I09.2 Chronic rheumatic pericarditis	0.447	0.552	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.447	0.552	0.000
I09.0 Rheumatic myocarditis	0.447	0.552	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.447	0.553	0.000
I05.8 Other mitral valve diseases	0.447	0.553	0.000
I27.9 Pulmonary heart disease, unspecified	0.431	0.569	0.000
I06.0 Rheumatic aortic stenosis	0.431	0.569	0.000
I05.2 Mitral stenosis with insufficiency	0.427	0.573	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.420	0.580	0.000
I06.8 Other rheumatic aortic valve diseases	0.420	0.580	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.420	0.580	0.000
I77.1 Stricture of artery	0.414	0.586	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.411	0.589	0.000
I07 Rheumatic tricuspid valve diseases	0.410	0.590	0.000
I06.1 Rheumatic aortic insufficiency	0.409	0.591	0.000
I74.5 Embolism and thrombosis of iliac artery	0.407	0.593	0.000
I79.1 Aortitis in diseases classified elsewhere	0.404	0.595	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.404	0.595	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.403	0.597	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.391	0.609	0.000
I05.1 Rheumatic mitral insufficiency	0.382	0.617	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.374	0.626	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.371	0.628	0.000
I28.1 Aneurysm of pulmonary artery	0.371	0.628	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.370	0.629	0.000
I01.8 Other acute rheumatic heart disease	0.370	0.629	0.000
I01.2 Acute rheumatic myocarditis	0.370	0.629	0.000
I01.1 Acute rheumatic endocarditis	0.370	0.629	0.000
I01.0 Acute rheumatic pericarditis	0.370	0.629	0.000
I02.9 Rheumatic chorea without heart involvement	0.370	0.629	0.000
I02.0 Rheumatic chorea with heart involvement	0.370	0.629	0.000
I77.8 Other specified disorders of arteries and arterioles	0.368	0.632	0.000
I72 Other aneurysm	0.368	0.632	0.000
I70.9 Generalised and unspecified atherosclerosis	0.365	0.635	0.000
I70.8 Atherosclerosis of other arteries	0.355	0.645	0.000
I74.8 Embolism and thrombosis of other arteries	0.346	0.653	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.344	0.656	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.324	0.676	0.000
I77.0 Arteriovenous fistula, acquired	0.318	0.682	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.316	0.684	0.000
I78 Diseases of capillaries	0.315	0.685	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.311	0.689	0.000
I70.0 Atherosclerosis of aorta	0.300	0.700	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.298	0.700	0.002
I07.9 Tricuspid valve disease, unspecified	0.294	0.706	0.000
I07.8 Other tricuspid valve diseases	0.294	0.706	0.000
I07.2 Tricuspid stenosis with insufficiency	0.294	0.706	0.000
I07.0 Tricuspid stenosis	0.294	0.706	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.287	0.713	0.000
I72.1 Aneurysm of artery of upper extremity	0.276	0.724	0.000
I72.9 Aneurysm of unspecified site	0.271	0.729	0.000
I72.0 Aneurysm of carotid artery	0.264	0.736	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.264	0.736	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.264	0.736	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.262	0.738	0.000
I72.2 Aneurysm of renal artery	0.261	0.739	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.256	0.744	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.255	0.745	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.254	0.746	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.251	0.749	0.001
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.249	0.751	0.000
I72.4 Aneurysm of artery of lower extremity	0.248	0.752	0.000
I28.8 Other specified diseases of pulmonary vessels	0.245	0.754	0.001
I78.8 Other diseases of capillaries	0.242	0.757	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.237	0.762	0.000
I12 Hypertensive renal disease	0.236	0.763	0.000
I72.8 Aneurysm of other specified arteries	0.229	0.771	0.000
I78.9 Disease of capillaries, unspecified	0.226	0.774	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.223	0.777	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.223	0.777	0.000
I98.0 Cardiovascular syphilis	0.223	0.777	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.220	0.779	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.215	0.785	0.000
I72.3 Aneurysm of iliac artery	0.204	0.796	0.000
I95 Hypotension	0.191	0.809	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.178	0.822	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.165	0.834	0.000
I95.0 Idiopathic hypotension	0.152	0.848	0.000
I95.2 Hypotension due to drugs	0.151	0.849	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.142	0.857	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.141	0.859	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.133	0.867	0.000
I95.8 Other hypotension	0.123	0.877	0.000
I07.1 Tricuspid insufficiency	0.118	0.881	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.114	0.886	0.000
I73 Other peripheral vascular diseases	0.096	0.904	0.000
I20.8 Other forms of angina pectoris	0.074	0.926	0.000
I73.8 Other specified peripheral vascular diseases	0.064	0.936	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.064	0.936	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.062	0.938	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.061	0.939	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.058	0.942	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.942	0.058
I12.0 Hypertensive renal disease with renal failure	0.057	0.943	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.050	0.950	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.047	0.952	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.047	0.953	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.046	0.954	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.044	0.955	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.044	0.956	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.043	0.957	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.040	0.960	0.000
E53 Deficiency of other B group vitamins	0.000	0.961	0.039
M05 Seropositive rheumatoid arthritis	0.038	0.962	0.000
I95.1 Orthostatic hypotension	0.037	0.963	0.000
I12.9 Hypertensive renal disease without renal failure	0.034	0.964	0.001
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.035	0.965	0.000
M05.2 Rheumatoid vasculitis	0.033	0.967	0.000
M05.8 Other seropositive rheumatoid arthritis	0.030	0.970	0.000
E50-E64 Other nutritional deficiencies	0.000	0.971	0.029
E61 Deficiency of other nutrient elements	0.000	0.972	0.028
M05.29 Rheumatoid vasculitis (Site unspecified)	0.028	0.972	0.000
E53.1 Pyridoxine deficiency	0.000	0.972	0.028
E53.0 Riboflavin deficiency	0.000	0.972	0.028
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.028	0.972	0.000
M05.1 Rheumatoid lung disease	0.028	0.972	0.000
M05.0 Felty's syndrome	0.028	0.972	0.000
E61.1 Iron deficiency	0.000	0.973	0.027
M05.20 Rheumatoid vasculitis (Multiple sites)	0.025	0.975	0.000
I71 Aortic aneurysm and dissection	0.024	0.976	0.000
E53.9 Vitamin B deficiency, unspecified	0.000	0.976	0.024
E61.2 Magnesium deficiency	0.000	0.976	0.024
I78.1 Naevus, nonneoplastic	0.023	0.976	0.001
M05.28 Rheumatoid vasculitis (Other)	0.024	0.976	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.024	0.976	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.024	0.976	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.024	0.976	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.024	0.976	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.024	0.976	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.024	0.976	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.024	0.976	0.000
E51 Thiamine deficiency	0.000	0.976	0.023
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.023	0.977	0.000
E56 Other vitamin deficiencies	0.000	0.978	0.022
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.021	0.978	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.021	0.978	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.021	0.978	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.021	0.978	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.021	0.978	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.021	0.978	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.021	0.978	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.021	0.978	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.021	0.978	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.979	0.021
E63 Other nutritional deficiencies	0.000	0.979	0.021
E50 Vitamin A deficiency	0.000	0.979	0.021
E60 Dietary zinc deficiency	0.000	0.979	0.021
E59 Dietary selenium deficiency	0.000	0.979	0.021
E54 Ascorbic acid deficiency	0.000	0.979	0.021
E52 Niacin deficiency [pellagra]	0.000	0.979	0.021
E61.9 Deficiency of nutrient element, unspecified	0.000	0.979	0.020
E61.8 Deficiency of other specified nutrient elements	0.000	0.979	0.020
E61.7 Deficiency of multiple nutrient elements	0.000	0.979	0.020
E61.6 Vanadium deficiency	0.000	0.979	0.020
E61.5 Molybdenum deficiency	0.000	0.979	0.020
E61.4 Chromium deficiency	0.000	0.979	0.020
E61.3 Manganese deficiency	0.000	0.979	0.020
E61.0 Copper deficiency	0.000	0.979	0.020
M05.09 Felty's syndrome (Site unspecified)	0.020	0.980	0.000
M05.08 Felty's syndrome (Other)	0.020	0.980	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.020	0.980	0.000
M05.06 Felty's syndrome (Lower leg)	0.020	0.980	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.020	0.980	0.000
M05.04 Felty's syndrome (Hand)	0.020	0.980	0.000
M05.03 Felty's syndrome (Forearm)	0.020	0.980	0.000
M05.02 Felty's syndrome (Upper arm)	0.020	0.980	0.000
M05.01 Felty's syndrome (Shoulder region)	0.020	0.980	0.000
M05.00 Felty's syndrome (Multiple sites)	0.020	0.980	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.020	0.980	0.000
M05.18 Rheumatoid lung disease (Other)	0.020	0.980	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.020	0.980	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.020	0.980	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.020	0.980	0.000
M05.14 Rheumatoid lung disease (Hand)	0.020	0.980	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.020	0.980	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.020	0.980	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.020	0.980	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.020	0.980	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.020	0.980	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.020	0.980	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.020	0.980	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.020	0.980	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.020	0.980	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.020	0.980	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.020	0.980	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.020	0.980	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.020	0.980	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.020	0.980	0.000
E51.2 Wernicke's encephalopathy	0.000	0.980	0.020
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.980	0.020
I73.0 Raynaud's syndrome	0.019	0.981	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.017	0.982	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.017	0.982	0.000
E56.1 Deficiency of vitamin K	0.000	0.982	0.018
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.983	0.017
E51.9 Thiamine deficiency, unspecified	0.000	0.983	0.017
E51.8 Other manifestations of thiamine deficiency	0.000	0.983	0.017
E51.1 Beriberi	0.000	0.983	0.017
E58 Dietary calcium deficiency	0.000	0.983	0.017
E56.9 Vitamin deficiency, unspecified	0.000	0.984	0.016
E56.8 Deficiency of other vitamins	0.000	0.984	0.016
E56.0 Deficiency of vitamin E	0.000	0.984	0.016
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.984	0.016
S62 Fracture at wrist and hand level	0.000	0.984	0.016
I71.1 Thoracic aortic aneurysm, ruptured	0.016	0.984	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.016	0.984	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.984	0.015
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.985	0.015
E50.9 Vitamin A deficiency, unspecified	0.000	0.985	0.015
E50.8 Other manifestations of vitamin A deficiency	0.000	0.985	0.015
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.985	0.015
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.985	0.015
E50.5 Vitamin A deficiency with night blindness	0.000	0.985	0.015
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.985	0.015
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.985	0.015
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.985	0.015
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.985	0.015
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.985	0.015
E63.9 Nutritional deficiency, unspecified	0.000	0.985	0.015
E63.8 Other specified nutritional deficiencies	0.000	0.985	0.015
E63.1 Imbalance of constituents of food intake	0.000	0.985	0.015
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.985	0.015
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.985	0.015
E64.8 Sequelae of other nutritional deficiencies	0.000	0.985	0.015
E64.3 Sequelae of rickets	0.000	0.985	0.015
E64.2 Sequelae of vitamin C deficiency	0.000	0.985	0.015
E64.1 Sequelae of vitamin A deficiency	0.000	0.985	0.015
E64.0 Sequelae of protein-energy malnutrition	0.000	0.985	0.015
E55 Vitamin D deficiency	0.000	0.985	0.015
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.014	0.985	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.985	0.015
D73.0 Hyposplenism	0.014	0.986	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.986	0.014
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.014	0.986	0.000
S62.5 Fracture of thumb	0.000	0.986	0.014
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.986	0.014
S62.51 Fracture of thumb (open)	0.000	0.987	0.013
H02.4 Ptosis of eyelid	0.013	0.987	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.987	0.013
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.987	0.013
S62.7 Multiple fractures of fingers	0.000	0.988	0.012
S62.1 Fracture of other carpal bone(s)	0.000	0.988	0.011
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.989	0.011
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.011	0.989	0.000
I71.0 Dissection of aorta [any part]	0.011	0.989	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.011	0.989	0.000
E55.0 Rickets, active	0.000	0.989	0.011
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.989	0.011
S62.21 Fracture of first metacarpal bone (open)	0.000	0.989	0.010
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.010	0.990	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.010	0.990	0.000
Z82.2 Family history of deafness and hearing loss	0.010	0.990	0.000
S62.71 Multiple fractures of fingers (open)	0.000	0.990	0.010
D73 Diseases of spleen	0.009	0.991	0.000
S62.6 Fracture of other finger	0.000	0.991	0.009
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.009	0.991	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.008	0.991	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.991	0.008
S62.3 Fracture of other metacarpal bone	0.000	0.991	0.008
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.992	0.008
D73.8 Other diseases of spleen	0.008	0.992	0.000
I73.9 Peripheral vascular disease, unspecified	0.008	0.992	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.008	0.992	0.000
S62.70 Multiple fractures of fingers (closed)	0.000	0.992	0.007
H53.8 Other visual disturbances	0.000	0.993	0.007
D73.1 Hypersplenism	0.007	0.993	0.000
S62.61 Fracture of other finger (open)	0.000	0.993	0.007
D73.3 Abscess of spleen	0.007	0.993	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.993	0.007
Z82.1 Family history of blindness and visual loss	0.007	0.993	0.000
D73.9 Disease of spleen, unspecified	0.007	0.993	0.000
D73.2 Chronic congestive splenomegaly	0.007	0.993	0.000
L50.0 Allergic urticaria	0.000	0.993	0.007
Z82.3 Family history of stroke	0.007	0.993	0.000
S62.50 Fracture of thumb (closed)	0.000	0.993	0.006
D73.5 Infarction of spleen	0.006	0.994	0.000
D73.4 Cyst of spleen	0.006	0.994	0.000
L50 Urticaria	0.000	0.994	0.006
S62.31 Fracture of other metacarpal bone (open)	0.000	0.994	0.006
L50.9 Urticaria, unspecified	0.000	0.994	0.006
L50.1 Idiopathic urticaria	0.000	0.994	0.006
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.995	0.005
S90 Superficial injury of ankle and foot	0.000	0.995	0.005
L50.8 Other urticaria	0.000	0.995	0.005
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.995	0.005
E55.9 Vitamin D deficiency, unspecified	0.000	0.995	0.005
L50.6 Contact urticaria	0.000	0.995	0.005
L50.5 Cholinergic urticaria	0.000	0.995	0.005
L50.4 Vibratory urticaria	0.000	0.995	0.005
L50.3 Dermatographic urticaria	0.000	0.995	0.005
L50.2 Urticaria due to cold and heat	0.000	0.995	0.005
S90.8 Other superficial injuries of ankle and foot	0.000	0.995	0.005
S90.1 Contusion of toe(s) without damage to nail	0.000	0.995	0.005
S90.3 Contusion of other and unspecified parts of foot	0.000	0.995	0.005
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.004	0.995	0.001
S90.0 Contusion of ankle	0.000	0.996	0.004
I95.9 Hypotension, unspecified	0.004	0.996	0.000
Z95.4 Presence of other heart-valve replacement	0.004	0.996	0.000
F20.0 Paranoid schizophrenia	0.000	0.996	0.004
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.996	0.004
S90.2 Contusion of toe(s) with damage to nail	0.000	0.996	0.004
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.996	0.004
H02.3 Blepharochalasis	0.004	0.996	0.000
H02 Other disorders of eyelid	0.004	0.996	0.000
H02.5 Other disorders affecting eyelid function	0.004	0.996	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.004	0.996	0.000
W22.9 Unspecified place	0.000	0.996	0.004
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.004	0.996	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.004	0.996	0.000
I60-I69 Cerebrovascular diseases	0.004	0.996	0.000
H02.8 Other specified disorders of eyelid	0.004	0.996	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.004	0.996	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.996	0.003
I65.2 Occlusion and stenosis of carotid artery	0.003	0.997	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.997	0.003
N84.2 Polyp of vagina	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.997	0.003
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.997	0.003
K25.3 Acute without haemorrhage or perforation	0.003	0.997	0.000
Z95.3 Presence of xenogenic heart valve	0.003	0.997	0.000
G58.9 Mononeuropathy, unspecified	0.003	0.997	0.000
G30 Alzheimer's disease	0.000	0.997	0.003
O24 Diabetes mellitus in pregnancy	0.000	0.997	0.003
H02.7 Other degenerative disorders of eyelid and periocular area	0.003	0.997	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.997	0.003
G31.0 Circumscribed brain atrophy	0.000	0.997	0.003
I65.1 Occlusion and stenosis of basilar artery	0.003	0.997	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.003	0.997	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
N82.3 Fistula of vagina to large intestine	0.000	0.997	0.003
R09.1 Pleurisy	0.003	0.997	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.003	0.997	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.003	0.997	0.000
F00 Dementia in Alzheimer's disease	0.000	0.997	0.003
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.997	0.003
H02.2 Lagophthalmos	0.003	0.997	0.000
J32.4 Chronic pansinusitis	0.000	0.997	0.003
S12.7 Multiple fractures of cervical spine	0.000	0.997	0.003
I68 Cerebrovascular disorders in diseases classified elsewhere	0.003	0.997	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.997	0.003
M79.60 Pain in limb (Multiple sites)	0.000	0.997	0.003
G45.4 Transient global amnesia	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.997	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
G30.8 Other Alzheimer's disease	0.000	0.997	0.003
R44.1 Visual hallucinations	0.000	0.997	0.003
S92.10 Fracture of talus (closed)	0.000	0.997	0.003
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.997	0.003
Z95.5 Presence of coronary angioplasty implant and graft	0.003	0.997	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.997	0.002
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.997	0.002
S12 Fracture of neck	0.000	0.997	0.002
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.998	0.002
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.998	0.002
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.998	0.002
G70.0 Myasthenia gravis	0.000	0.998	0.002
G30-G32 Other degenerative diseases of the nervous system	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
S12.1 Fracture of second cervical vertebra	0.000	0.998	0.002
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.998	0.002
H02.0 Entropion and trichiasis of eyelid	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.000	0.998	0.002
I62 Other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
Z50.5 Speech therapy	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.000	0.998	0.002
S12.71 Multiple fractures of cervical spine (open)	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.000	0.998	0.002
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.002	0.998	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.002	0.998	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.000	0.998	0.002
Z95.1 Presence of aortocoronary bypass graft	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.998	0.002
M25.56 Pain in joint (Lower leg)	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.002
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.998	0.002
F02 Dementia in other diseases classified elsewhere	0.000	0.998	0.002
F60 Specific personality disorders	0.000	0.998	0.002
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.998	0.002
S62.60 Fracture of other finger (closed)	0.000	0.998	0.002
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.000	0.998	0.002
I68.0 Cerebral amyloid angiopathy	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations