TreeWAS – Variant ID: rs11953630

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.000	1.000
I10-I15 Hypertensive diseases	0.000	0.664	0.336
I11 Hypertensive heart disease	0.000	0.739	0.261
I15 Secondary hypertension	0.000	0.779	0.221
I13 Hypertensive heart and renal disease	0.000	0.787	0.212
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.787	0.212
Z95.1 Presence of aortocoronary bypass graft	0.000	0.793	0.207
I08 Multiple valve diseases	0.000	0.801	0.199
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.802	0.198
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.806	0.194
I08.0 Disorders of both mitral and aortic valves	0.000	0.806	0.194
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.808	0.192
I05-I09 Chronic rheumatic heart diseases	0.000	0.810	0.190
I05 Rheumatic mitral valve diseases	0.000	0.819	0.181
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.821	0.179
I15.9 Seconday hypertension, unspecified	0.000	0.822	0.178
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.825	0.175
Z95.2 Presence of prosthetic heart valve	0.000	0.827	0.173
I05.2 Mitral stenosis with insufficiency	0.000	0.828	0.172
Chapter IX Diseases of the circulatory system	0.000	0.833	0.167
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.841	0.159
I15.8 Other secondary hypertension	0.000	0.841	0.159
Z95.4 Presence of other heart-valve replacement	0.000	0.842	0.158
I08.8 Other multiple valve diseases	0.000	0.847	0.153
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.847	0.152
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.847	0.152
I15.0 Renovascular hypertension	0.000	0.850	0.150
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.850	0.150
I60 Subarachnoid haemorrhage	0.000	0.851	0.149
I15.2 Hypertension secondary to endocrine disorders	0.000	0.851	0.149
I09 Other rheumatic heart diseases	0.000	0.858	0.142
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.859	0.141
I60-I69 Cerebrovascular diseases	0.000	0.859	0.141
Z95.3 Presence of xenogenic heart valve	0.000	0.859	0.141
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.861	0.138
I08.9 Multiple valve disease, unspecified	0.000	0.863	0.137
I05.1 Rheumatic mitral insufficiency	0.000	0.864	0.136
I05.9 Mitral valve disease, unspecified	0.000	0.865	0.135
I05.0 Mitral stenosis	0.000	0.866	0.133
I15.1 Hypertension secondary to other renal disorders	0.000	0.867	0.133
I06 Rheumatic aortic valve diseases	0.000	0.868	0.132
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.868	0.132
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.869	0.131
I05.8 Other mitral valve diseases	0.000	0.870	0.130
I62 Other nontraumatic intracranial haemorrhage	0.000	0.872	0.128
I12 Hypertensive renal disease	0.000	0.881	0.119
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.883	0.117
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.884	0.116
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.884	0.116
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.888	0.112
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.888	0.112
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.888	0.112
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.890	0.110
I00-I02 Acute rheumatic fever	0.000	0.890	0.110
I09.9 Rheumatic heart disease, unspecified	0.000	0.892	0.107
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.893	0.107
I61 Intracerebral haemorrhage	0.000	0.896	0.104
I07 Rheumatic tricuspid valve diseases	0.000	0.898	0.102
I09.8 Other specified rheumatic heart diseases	0.000	0.898	0.102
I09.2 Chronic rheumatic pericarditis	0.000	0.898	0.102
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.898	0.102
I09.0 Rheumatic myocarditis	0.000	0.898	0.102
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.898	0.102
I62.1 Nontraumatic extradural haemorrhage	0.000	0.901	0.099
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.902	0.098
I95.1 Orthostatic hypotension	0.000	0.904	0.096
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.904	0.096
I06.1 Rheumatic aortic insufficiency	0.000	0.904	0.096
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.904	0.096
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.905	0.095
I06.8 Other rheumatic aortic valve diseases	0.000	0.905	0.095
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.905	0.095
I95 Hypotension	0.000	0.909	0.091
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.909	0.091
I06.0 Rheumatic aortic stenosis	0.000	0.910	0.090
I68.0 Cerebral amyloid angiopathy	0.000	0.912	0.088
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.913	0.087
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.917	0.083
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.921	0.079
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.921	0.079
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.921	0.079
I02 Rheumatic chorea	0.000	0.921	0.079
I01 Rheumatic fever with heart involvement	0.000	0.921	0.079
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.923	0.077
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.924	0.076
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.926	0.074
I07.9 Tricuspid valve disease, unspecified	0.000	0.926	0.073
I07.8 Other tricuspid valve diseases	0.000	0.926	0.073
I07.2 Tricuspid stenosis with insufficiency	0.000	0.926	0.073
I07.0 Tricuspid stenosis	0.000	0.926	0.073
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.927	0.073
I95.0 Idiopathic hypotension	0.000	0.927	0.073
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.930	0.070
I00 Rheumatic fever without mention of heart involvement	0.000	0.930	0.069
I20-I25 Ischaemic heart diseases	0.000	0.930	0.070
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.931	0.069
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.931	0.069
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.931	0.069
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.933	0.067
I61.8 Other intracerebral haemorrhage	0.000	0.936	0.064
I60.8 Other subarachnoid haemorrhage	0.000	0.936	0.064
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.936	0.063
E78.0 Pure hypercholesterolaemia	0.000	0.937	0.063
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.938	0.062
I28 Other diseases of pulmonary vessels	0.000	0.938	0.062
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.938	0.062
I95.8 Other hypotension	0.000	0.939	0.061
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.940	0.060
I30-I52 Other forms of heart disease	0.000	0.942	0.058
I51 Complications and ill-defined descriptions of heart disease	0.000	0.943	0.057
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.943	0.057
I01.8 Other acute rheumatic heart disease	0.000	0.943	0.057
I01.2 Acute rheumatic myocarditis	0.000	0.943	0.057
I01.1 Acute rheumatic endocarditis	0.000	0.943	0.057
I01.0 Acute rheumatic pericarditis	0.000	0.943	0.057
I02.9 Rheumatic chorea without heart involvement	0.000	0.943	0.057
I02.0 Rheumatic chorea with heart involvement	0.000	0.943	0.057
I51.8 Other ill-defined heart diseases	0.000	0.943	0.057
I25 Chronic ischaemic heart disease	0.000	0.943	0.057
I34 Nonrheumatic mitral valve disorders	0.000	0.943	0.057
I20.8 Other forms of angina pectoris	0.000	0.944	0.056
I99 Other and unspecified disorders of circulatory system	0.000	0.944	0.055
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.944	0.055
I33 Acute and subacute endocarditis	0.000	0.945	0.055
I20 Angina pectoris	0.000	0.945	0.055
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.945	0.055
I28.8 Other specified diseases of pulmonary vessels	0.000	0.946	0.054
I33.0 Acute and subacute infective endocarditis	0.000	0.947	0.053
I51.6 Cardiovascular disease, unspecified	0.000	0.947	0.053
I25.1 Atherosclerotic heart disease	0.000	0.949	0.051
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.949	0.051
I34.0 Mitral (valve) insufficiency	0.000	0.951	0.049
I12.9 Hypertensive renal disease without renal failure	0.000	0.951	0.049
I51.0 Cardiac septal defect, acquired	0.000	0.952	0.048
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.953	0.047
I34.1 Mitral (valve) prolapse	0.000	0.953	0.047
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.954	0.046
I23 Certain current complications following acute myocardial infarction	0.000	0.955	0.045
I12.0 Hypertensive renal disease with renal failure	0.000	0.955	0.045
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.955	0.045
I28.1 Aneurysm of pulmonary artery	0.000	0.955	0.045
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.955	0.045
I35 Nonrheumatic aortic valve disorders	0.000	0.956	0.044
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.956	0.044
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.957	0.043
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.958	0.042
I52 Other heart disorders in diseases classified elsewhere	0.000	0.958	0.042
I48 Atrial fibrillation and flutter	0.000	0.958	0.042
I41 Myocarditis in diseases classified elsewhere	0.000	0.958	0.042
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.958	0.042
I32 Pericarditis in diseases classified elsewhere	0.000	0.958	0.042
I35.1 Aortic (valve) insufficiency	0.000	0.958	0.042
I51.9 Heart disease, unspecified	0.000	0.958	0.042
I36 Nonrheumatic tricuspid valve disorders	0.000	0.958	0.042
I25.4 Coronary artery aneurysm	0.000	0.959	0.041
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.959	0.041
I25.6 Silent myocardial ischaemia	0.000	0.959	0.041
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.959	0.041
I33.9 Acute endocarditis, unspecified	0.000	0.959	0.041
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.959	0.041
I25.5 Ischaemic cardiomyopathy	0.000	0.960	0.040
I42 Cardiomyopathy	0.000	0.960	0.040
I45 Other conduction disorders	0.000	0.960	0.040
I25.3 Aneurysm of heart	0.000	0.960	0.039
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.961	0.039
I07.1 Tricuspid insufficiency	0.000	0.961	0.039
I42.2 Other hypertrophic cardiomyopathy	0.000	0.962	0.038
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.962	0.038
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.963	0.037
I51.5 Myocardial degeneration	0.000	0.963	0.037
I40 Acute myocarditis	0.000	0.963	0.037
I63 Cerebral infarction	0.000	0.963	0.037
I51.4 Myocarditis, unspecified	0.000	0.963	0.037
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.963	0.036
I45.5 Other specified heart block	0.000	0.964	0.036
I50 Heart failure	0.000	0.964	0.036
I45.8 Other specified conduction disorders	0.000	0.964	0.036
I24 Other acute ischaemic heart diseases	0.000	0.965	0.035
I37 Pulmonary valve disorders	0.000	0.965	0.035
I49 Other cardiac arrhythmias	0.000	0.965	0.035
I65.1 Occlusion and stenosis of basilar artery	0.000	0.965	0.035
I25.2 Old myocardial infarction	0.000	0.965	0.035
I35.9 Aortic valve disorder, unspecified	0.000	0.966	0.034
I26 Pulmonary embolism	0.000	0.966	0.034
I22 Subsequent myocardial infarction	0.000	0.966	0.034
I21 Acute myocardial infarction	0.000	0.966	0.034
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.966	0.033
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.967	0.033
I42.8 Other cardiomyopathies	0.000	0.967	0.033
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.967	0.033
I95.2 Hypotension due to drugs	0.000	0.967	0.033
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.967	0.032
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.967	0.032
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.967	0.032
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.967	0.032
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.967	0.032
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.967	0.032
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.967	0.032
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.968	0.032
I50.0 Congestive heart failure	0.000	0.968	0.032
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.969	0.031
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.969	0.031
I49.1 Atrial premature depolarisation	0.000	0.969	0.031
I45.4 Nonspecific intraventricular block	0.000	0.969	0.031
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.969	0.031
I38 Endocarditis, valve unspecified	0.000	0.969	0.031
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.969	0.030
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.969	0.030
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.969	0.030
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.969	0.030
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.969	0.030
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.969	0.030
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.969	0.030
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.969	0.030
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.969	0.030
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.969	0.030
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.969	0.030
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.969	0.030
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.969	0.030
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.969	0.030
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.969	0.030
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.969	0.030
I48.4 Atypical atrial flutter	0.000	0.969	0.030
I48.3 Typical atrial flutter	0.000	0.969	0.030
I48.2 Chronic atrial fibrillation	0.000	0.969	0.030
I48.1 Persistent atrial fibrillation	0.000	0.969	0.030
I48.0 Paroxysmal atrial fibrillation	0.000	0.969	0.030
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.969	0.030
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.969	0.030
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.969	0.030
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.970	0.030
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.970	0.030
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.970	0.030
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.970	0.030
I45.2 Bifascicular block	0.000	0.970	0.030
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.970	0.030
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.970	0.029
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.970	0.029
I98.0 Cardiovascular syphilis	0.000	0.970	0.029
I49.0 Ventricular fibrillation and flutter	0.000	0.971	0.029
I42.5 Other restrictive cardiomyopathy	0.000	0.971	0.029
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.971	0.029
I45.0 Right fascicular block	0.000	0.971	0.029
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.971	0.029
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.972	0.028
I23.8 Other current complications following acute myocardial infarction	0.000	0.972	0.027
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.972	0.027
I35.0 Aortic (valve) stenosis	0.000	0.973	0.027
I49.5 Sick sinus syndrome	0.000	0.973	0.027
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.973	0.027
I40.8 Other acute myocarditis	0.000	0.973	0.027
I40.1 Isolated myocarditis	0.000	0.973	0.027
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.973	0.027
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.973	0.027
I24.1 Dressler's syndrome	0.000	0.973	0.027
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.974	0.026
I49.8 Other specified cardiac arrhythmias	0.000	0.974	0.026
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.974	0.026
I40.0 Infective myocarditis	0.000	0.974	0.026
I42.4 Endocardial fibroelastosis	0.000	0.974	0.025
I37.9 Pulmonary valve disorder, unspecified	0.000	0.975	0.025
I37.8 Other pulmonary valve disorders	0.000	0.975	0.025
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.975	0.025
I49.2 Junctional premature depolarisation	0.000	0.975	0.025
I97.1 Other functional disturbances following cardiac surgery	0.000	0.975	0.025
I45.9 Conduction disorder, unspecified	0.000	0.975	0.025
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.975	0.025
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.975	0.025
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.975	0.025
I37.0 Pulmonary valve stenosis	0.000	0.975	0.024
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.975	0.025
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.975	0.025
I20.0 Unstable angina	0.000	0.976	0.024
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.976	0.024
I97.0 Postcardiotomy syndrome	0.000	0.976	0.024
Z95.0 Presence of cardiac pacemaker	0.000	0.976	0.024
I20.9 Angina pectoris, unspecified	0.000	0.976	0.024
I42.6 Alcoholic cardiomyopathy	0.000	0.976	0.024
I24.8 Other forms of acute ischaemic heart disease	0.000	0.976	0.024
I30 Acute pericarditis	0.001	0.977	0.022
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.977	0.023
I40.9 Acute myocarditis, unspecified	0.000	0.977	0.022
I49.4 Other and unspecified premature depolarisation	0.000	0.978	0.022
I45.3 Trifascicular block	0.000	0.978	0.022
I47 Paroxysmal tachycardia	0.000	0.978	0.022
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.979	0.021
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.979	0.021
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.979	0.021
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.979	0.021
I22.8 Subsequent myocardial infarction of other sites	0.000	0.979	0.021
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.979	0.021
I20.1 Angina pectoris with documented spasm	0.000	0.979	0.021
I37.1 Pulmonary valve insufficiency	0.000	0.980	0.020
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.981	0.019
O41.0 Oligohydramnios	0.019	0.981	0.000
I67 Other cerebrovascular diseases	0.000	0.981	0.019
I50.9 Heart failure, unspecified	0.000	0.981	0.019
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.982	0.018
I47.0 Reentry ventricular arrhythmia	0.000	0.982	0.018
O41.8 Other specified disorders of amniotic fluid and membranes	0.018	0.982	0.000
I47.2 Ventricular tachycardia	0.000	0.983	0.017
O41 Other disorders of amniotic fluid and membranes	0.017	0.983	0.000
I30.8 Other forms of acute pericarditis	0.001	0.983	0.016
I30.0 Acute nonspecific idiopathic pericarditis	0.001	0.983	0.016
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.984	0.016
I35.8 Other aortic valve disorders	0.000	0.984	0.016
I31 Other diseases of pericardium	0.000	0.985	0.015
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.985	0.015
I45.1 Other and unspecified right bundle-branch block	0.000	0.985	0.015
I63.8 Other cerebral infarction	0.000	0.985	0.015
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.985	0.015
I50.1 Left ventricular failure	0.000	0.986	0.014
I67.2 Cerebral atherosclerosis	0.000	0.986	0.014
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.986	0.014
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.986	0.014
I67.5 Moyamoya disease	0.000	0.986	0.014
I67.4 Hypertensive encephalopathy	0.000	0.986	0.014
I67.3 Progressive vascular leukoencephalopathy	0.000	0.986	0.014
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.986	0.014
I30.1 Infective pericarditis	0.001	0.987	0.013
I69 Sequelae of cerebrovascular disease	0.000	0.987	0.013
I31.0 Chronic adhesive pericarditis	0.000	0.987	0.013
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.013	0.987	0.000
C67.6 Ureteric orifice	0.013	0.987	0.000
I49.3 Ventricular premature depolarisation	0.000	0.987	0.013
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.987	0.013
C67.2 Lateral wall of bladder	0.012	0.988	0.000
I46 Cardiac arrest	0.000	0.988	0.012
C55 Malignant neoplasm of uterus, part unspecified	0.012	0.988	0.000
C67 Malignant neoplasm of bladder	0.012	0.988	0.000
O41.1 Infection of amniotic sac and membranes	0.012	0.988	0.000
C56 Malignant neoplasm of ovary	0.012	0.988	0.000
C67.4 Posterior wall of bladder	0.012	0.988	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.988	0.012
I63.9 Cerebral infarction, unspecified	0.000	0.989	0.011
K01.1 Impacted teeth	0.000	0.989	0.011
I31.8 Other specified diseases of pericardium	0.000	0.989	0.011
I31.2 Haemopericardium, not elsewhere classified	0.000	0.989	0.011
I45.6 Preexcitation syndrome	0.000	0.989	0.011
C67.3 Anterior wall of bladder	0.011	0.989	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.989	0.010
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.989	0.010
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.990	0.010
C67.0 Trigone of bladder	0.010	0.990	0.000
C51-C58 Malignant neoplasms of female genital organs	0.010	0.990	0.000
L81.4 Other melanin hyperpigmentation	0.010	0.990	0.000
T39.1 4-Aminophenol derivatives	0.000	0.990	0.010
I21.4 Acute subendocardial myocardial infarction	0.000	0.990	0.010
C57 Malignant neoplasm of other and unspecified female genital organs	0.010	0.990	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.990	0.010
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.991	0.009
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.991	0.009
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.991	0.009
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.991	0.009
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.991	0.009
I27 Other pulmonary heart diseases	0.000	0.991	0.009
T39.0 Salicylates	0.000	0.991	0.009
I46.1 Sudden cardiac death, so described	0.000	0.991	0.009
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.991	0.009
I42.9 Cardiomyopathy, unspecified	0.000	0.991	0.009
C67.7 Urachus	0.009	0.991	0.000
I31.1 Chronic constrictive pericarditis	0.000	0.991	0.008
C57.0 Fallopian tube	0.009	0.991	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.991	0.008
C57.9 Female genital organ, unspecified	0.008	0.992	0.000
C67.5 Bladder neck	0.008	0.992	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.992	0.008
Z57.2 Occupational exposure to dust	0.008	0.992	0.000
C58 Malignant neoplasm of placenta	0.007	0.992	0.000
C67.8 Overlapping lesion of bladder	0.007	0.992	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.992	0.008
K74.6 Other and unspecified cirrhosis of liver	0.008	0.992	0.000
I42.0 Dilated cardiomyopathy	0.000	0.993	0.007
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.993	0.007
I98.2 Oesophageal varices in diseases classified elsewhere	0.001	0.993	0.006
C57.8 Overlapping lesion of female genital organs	0.007	0.993	0.000
C57.7 Other specified female genital organs	0.007	0.993	0.000
C57.4 Uterine adnexa, unspecified	0.007	0.993	0.000
C57.3 Parametrium	0.007	0.993	0.000
C57.2 Round ligament	0.007	0.993	0.000
C57.1 Broad ligament	0.007	0.993	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.993	0.007
M46 Other inflammatory spondylopathies	0.000	0.993	0.007
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.993	0.007
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.993	0.007
I27.1 Kyphoscoliotic heart disease	0.000	0.993	0.007
C54 Malignant neoplasm of corpus uteri	0.006	0.994	0.000
K26.7 Chronic without haemorrhage or perforation	0.000	0.994	0.006
I67.8 Other specified cerebrovascular diseases	0.000	0.994	0.006
C53 Malignant neoplasm of cervix uteri	0.006	0.994	0.000
Z57 Occupational exposure to risk-factors	0.006	0.994	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.006	0.994	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.006	0.994	0.000
C51 Malignant neoplasm of vulva	0.006	0.994	0.000
C52 Malignant neoplasm of vagina	0.006	0.994	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.000	0.994	0.006
C67.1 Dome of bladder	0.006	0.994	0.000
I30.9 Acute pericarditis, unspecified	0.001	0.994	0.005
C54.9 Corpus uteri, unspecified	0.006	0.994	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.994	0.006
M46.3 Infection of intervertebral disk (pyogenic)	0.000	0.994	0.006
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.994	0.005
M46.0 Spinal enthesopathy	0.000	0.994	0.006
Z57.3 Occupational exposure to other air contaminants	0.006	0.994	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.994	0.005
I47.9 Paroxysmal tachycardia, unspecified	0.001	0.994	0.005
T39.4 Antirheumatics, not elsewhere classified	0.000	0.994	0.005
T39.2 Pyrazolone derivatives	0.000	0.994	0.005
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.994	0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.994	0.006
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.001	0.995	0.005
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.995	0.005
M46.8 Other specified inflammatory spondylopathies	0.000	0.995	0.005
M46.5 Other infective spondylopathies	0.000	0.995	0.005
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.000	0.995	0.005
I67.1 Cerebral aneurysm, nonruptured	0.000	0.995	0.005
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.995	0.005
K14.8 Other diseases of tongue	0.005	0.995	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.995	0.005
M46.2 Osteomyelitis of vertebra	0.000	0.995	0.005
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.995	0.005
I69.0 Sequelae of subarachnoid haemorrhage	0.001	0.995	0.005
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.995	0.005
Z82.3 Family history of stroke	0.000	0.995	0.005
C51.1 Labium minus	0.005	0.995	0.000
M46.4 Discitis, unspecified	0.000	0.995	0.005
C54.8 Overlapping lesion of corpus uteri	0.005	0.995	0.000
C54.3 Fundus uteri	0.005	0.995	0.000
C54.2 Myometrium	0.005	0.995	0.000
C54.0 Isthmus uteri	0.005	0.995	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.000	0.995	0.005
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.995	0.005
C53.8 Overlapping lesion of cervix uteri	0.005	0.995	0.000
C53.1 Exocervix	0.005	0.995	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.005	0.995	0.000
Z57.7 Occupational exposure to vibration	0.005	0.995	0.000
Z57.6 Occupational exposure to extreme temperature	0.005	0.995	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.005	0.995	0.000
Z57.1 Occupational exposure to radiation	0.005	0.995	0.000
Z57.0 Occupational exposure to noise	0.005	0.995	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.995	0.005
R47.0 Dysphasia and aphasia	0.000	0.995	0.005
K74 Fibrosis and cirrhosis of liver	0.005	0.995	0.000
C51.8 Overlapping lesion of vulva	0.005	0.995	0.000
C51.2 Clitoris	0.005	0.995	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.995	0.005
K74.5 Biliary cirrhosis, unspecified	0.005	0.995	0.000
K01 Embedded and impacted teeth	0.000	0.995	0.005
C53.0 Endocervix	0.005	0.995	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.000	0.995	0.004
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.000	0.995	0.004
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.000	0.995	0.004
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.000	0.995	0.004
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.000	0.995	0.004
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.000	0.995	0.004
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.000	0.995	0.004
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.000	0.995	0.004
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.000	0.995	0.005
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.995	0.005
Z57.8 Occupational exposure to other risk-factors	0.005	0.995	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.000	0.995	0.004
C51.0 Labium majus	0.004	0.995	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.000	0.995	0.004
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.000	0.995	0.004
T78 Adverse effects, not elsewhere classified	0.005	0.995	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.995	0.005
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.996	0.004
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.000	0.996	0.004
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.000	0.996	0.004
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.000	0.996	0.004
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.000	0.996	0.004
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.000	0.996	0.004
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.000	0.996	0.004
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.000	0.996	0.004
M46.09 Spinal enthesopathy (Site unspecified)	0.000	0.996	0.004
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M46.07 Spinal enthesopathy (Lumbosacral region)	0.000	0.996	0.004
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.000	0.996	0.004
M46.04 Spinal enthesopathy (Thoracic region)	0.000	0.996	0.004
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.000	0.996	0.004
M46.02 Spinal enthesopathy (Cervical region)	0.000	0.996	0.004
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.000	0.996	0.004
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.000	0.996	0.004
I77 Other disorders of arteries and arterioles	0.000	0.996	0.004
D86 Sarcoidosis	0.004	0.996	0.000
D26.1 Corpus uteri	0.004	0.996	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.000	0.996	0.004
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M46.57 Other infective spondylopathies (Lumbosacral region)	0.000	0.996	0.004
M46.56 Other infective spondylopathies (Lumbar region)	0.000	0.996	0.004
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.000	0.996	0.004
M46.54 Other infective spondylopathies (Thoracic region)	0.000	0.996	0.004
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.000	0.996	0.004
M46.52 Other infective spondylopathies (Cervical region)	0.000	0.996	0.004
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.000	0.996	0.004
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.000	0.996	0.004
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.000	0.996	0.004
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations