TreeWAS – Variant ID: rs11965214

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
M07.3 Other psoriatic arthropathies	1.000	0.000	0.000
E10.9 Without complications	0.000	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.002	0.998
E10-E14 Diabetes mellitus	0.000	0.002	0.998
N20 Calculus of kidney and ureter	0.998	0.002	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.997	0.003	0.000
# Top node	0.997	0.003	0.000
M07 Psoriatic and enteropathic arthropathies	0.997	0.003	0.000
N20-N23 Urolithiasis	0.997	0.003	0.000
Chapter XIV Diseases of the genitourinary system	0.996	0.004	0.000
M05-M14 Inflammatory polyarthropathies	0.996	0.004	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.995	0.005	0.000
N20.0 Calculus of kidney	0.994	0.006	0.000
L40-L45 Papulosquamous disorders	0.993	0.007	0.000
N20.1 Calculus of ureter	0.991	0.009	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.990	0.010	0.000
N10-N16 Renal tubulo-interstitial diseases	0.989	0.011	0.000
N13 Obstructive and reflux uropathy	0.988	0.012	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.013	0.987
Chapter V Mental and behavioural disorders	0.987	0.013	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.969	0.031	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.038	0.962
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.953	0.047	0.000
M86-M90 Other osteopathies	0.951	0.049	0.000
F30-F39 Mood [affective] disorders	0.950	0.050	0.000
M45-M49 Spondylopathies	0.947	0.053	0.000
L40.0 Psoriasis vulgaris	0.938	0.062	0.000
E10.4 With neurological complications	0.000	0.067	0.933
F17 Mental and behavioural disorders due to use of tobacco	0.929	0.071	0.000
E10.3 With ophthalmic complications	0.000	0.072	0.928
E50-E64 Other nutritional deficiencies	0.000	0.076	0.924
F17.1 Harmful use	0.923	0.077	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.080	0.920
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.908	0.092	0.000
M47 Spondylosis	0.907	0.093	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.904	0.096	0.000
N13.8 Other obstructive and reflux uropathy	0.901	0.099	0.000
M40-M43 Deforming dorsopathies	0.898	0.102	0.000
M47.8 Other spondylosis	0.897	0.103	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.896	0.104	0.000
Chapter II Neoplasms	0.891	0.109	0.000
N21 Calculus of lower urinary tract	0.877	0.123	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.873	0.127	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.869	0.131	0.000
N60-N64 Disorders of breast	0.869	0.131	0.000
E10.5 With peripheral circulatory complications	0.000	0.133	0.867
E10.1 With ketoacidosis	0.000	0.139	0.861
T15-T19 Effects of foreign body entering through natural orifice	0.860	0.140	0.000
N20.9 Urinary calculus, unspecified	0.855	0.145	0.000
L40.8 Other psoriasis	0.855	0.145	0.000
Chapter VI Diseases of the nervous system	0.853	0.147	0.000
M46 Other inflammatory spondylopathies	0.847	0.153	0.000
E55 Vitamin D deficiency	0.000	0.153	0.847
M47.89 Other spondylosis (Site unspecified)	0.846	0.154	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.846	0.154	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.845	0.155	0.000
F31 Bipolar affective disorder	0.843	0.157	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.843	0.157	0.000
F30 Manic episode	0.839	0.161	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.838	0.162	0.000
E06 Thyroiditis	0.000	0.164	0.836
N13.6 Pyonephrosis	0.834	0.166	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.827	0.173	0.000
M89 Other disorders of bone	0.824	0.176	0.000
M87 Osteonecrosis	0.823	0.177	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.822	0.178	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.815	0.185	0.000
D00-D09 In situ neoplasms	0.815	0.185	0.000
M43 Other deforming dorsopathies	0.812	0.188	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.811	0.189	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.189	0.811
M91-M94 Chondropathies	0.810	0.190	0.000
N63 Unspecified lump in breast	0.806	0.194	0.000
E10.2 With renal complications	0.000	0.195	0.805
M50-M54 Other dorsopathies	0.803	0.197	0.000
E13 Other specified diabetes mellitus	0.000	0.197	0.803
F11 Mental and behavioural disorders due to use of opioids	0.803	0.197	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.803	0.197	0.000
C64-C68 Malignant neoplasms of urinary tract	0.803	0.197	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.798	0.202	0.000
M47.82 Other spondylosis (Cervical region)	0.796	0.204	0.000
T18 Foreign body in alimentary tract	0.795	0.205	0.000
S10-S19 Injuries to the neck	0.792	0.208	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.209	0.791
N21.0 Calculus in bladder	0.790	0.210	0.000
G20-G26 Extrapyramidal and movement disorders	0.788	0.212	0.000
M00-M03 Infectious arthropathies	0.788	0.212	0.000
M86 Osteomyelitis	0.786	0.214	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.786	0.214	0.000
T43.2 Other and unspecified antidepressants	0.782	0.218	0.000
G40-G47 Episodic and paroxysmal disorders	0.779	0.221	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.774	0.225	0.000
F32 Depressive episode	0.773	0.227	0.000
G40 Epilepsy	0.772	0.228	0.000
N13.4 Hydroureter	0.772	0.228	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.771	0.229	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.770	0.230	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.770	0.230	0.000
C34 Malignant neoplasm of bronchus and lung	0.770	0.230	0.000
Chapter I Certain infectious and parasitic diseases	0.767	0.233	0.000
N64 Other disorders of breast	0.766	0.234	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.762	0.238	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.759	0.241	0.000
E53 Deficiency of other B group vitamins	0.000	0.242	0.758
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.758	0.242	0.000
M50 Cervical disk disorders	0.754	0.246	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.749	0.251	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.746	0.254	0.000
M60-M63 Disorders of muscles	0.746	0.254	0.000
M43.1 Spondylolisthesis	0.744	0.256	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.744	0.256	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.743	0.257	0.000
M89.9 Disorder of bone, unspecified	0.740	0.260	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.739	0.261	0.000
B95-B98 Bacterial, viral and other infectious agents	0.739	0.261	0.000
L42 Pityriasis rosea	0.738	0.262	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.737	0.263	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.737	0.263	0.000
G24 Dystonia	0.735	0.265	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.735	0.265	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.733	0.267	0.000
F99-F99 Unspecified mental disorder	0.730	0.270	0.000
N61 Inflammatory disorders of breast	0.728	0.272	0.000
T18.1 Foreign body in oesophagus	0.728	0.272	0.000
M88 Paget's disease of bone [osteitis deformans]	0.726	0.274	0.000
Q50-Q56 Congenital malformations of genital organs	0.726	0.274	0.000
N11 Chronic tubulo-interstitial nephritis	0.724	0.276	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.724	0.276	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.723	0.277	0.000
F41 Other anxiety disorders	0.719	0.281	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E10.8 With unspecified complications	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
E10.6 With other specified complications	0.000	0.283	0.717
E10.0 With coma	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.283	0.717
M07.38 Other psoriatic arthropathies (Other)	0.717	0.283	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.717	0.283	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.717	0.283	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.717	0.283	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.717	0.283	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.716	0.284	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.716	0.284	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.284	0.716
F32.0 Mild depressive episode	0.716	0.284	0.000
T17 Foreign body in respiratory tract	0.716	0.284	0.000
E03.8 Other specified hypothyroidism	0.000	0.285	0.715
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285	0.000
M07.6 Other enteropathic arthropathies	0.715	0.285	0.000
M07.5 Arthropathy in ulcerative colitis	0.715	0.285	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.715	0.285	0.000
M07.2 Psoriatic spondylitis	0.715	0.285	0.000
M07.1 Arthritis mutilans	0.715	0.285	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.715	0.285	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.715	0.285	0.000
S31 Open wound of abdomen, lower back and pelvis	0.714	0.286	0.000
M12 Other specific arthropathies	0.714	0.286	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.714	0.286	0.000
M08 Juvenile arthritis	0.714	0.286	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.713	0.286	0.000
D06 Carcinoma in situ of cervix uteri	0.713	0.287	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.712	0.288	0.000
L44 Other papulosquamous disorders	0.712	0.288	0.000
L41 Parapsoriasis	0.712	0.288	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.712	0.288	0.000
M50.3 Other cervical disk degeneration	0.711	0.289	0.000
L10-L14 Bullous disorders	0.710	0.290	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.709	0.291	0.000
N15 Other renal tubulo-interstitial diseases	0.709	0.291	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.709	0.291	0.000
F60-F69 Disorders of adult personality and behaviour	0.709	0.291	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.708	0.292	0.000
E05.8 Other thyrotoxicosis	0.000	0.292	0.708
E05.5 Thyroid crisis or storm	0.000	0.292	0.708
E05.4 Thyrotoxicosis factitia	0.000	0.292	0.708
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.292	0.708
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.292	0.708
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.707	0.293	0.000
F70-F79 Mental retardation	0.707	0.293	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.707	0.293	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.706	0.294	0.000
M14 Arthropathies in other diseases classified elsewhere	0.704	0.296	0.000
E06.3 Autoimmune thyroiditis	0.000	0.298	0.702
M43.16 Spondylolisthesis (Lumbar region)	0.702	0.298	0.000
S80-S89 Injuries to the knee and lower leg	0.702	0.298	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.699	0.301	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.697	0.303	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.696	0.304	0.000
F33 Recurrent depressive disorder	0.696	0.304	0.000
D07.5 Prostate	0.695	0.305	0.000
F30.2 Mania with psychotic symptoms	0.693	0.307	0.000
T00-T07 Injuries involving multiple body regions	0.693	0.307	0.000
F39 Unspecified mood [affective] disorder	0.692	0.308	0.000
F80-F89 Disorders of psychological development	0.688	0.312	0.000
E40-E46 Malnutrition	0.000	0.315	0.685
M41 Scoliosis	0.684	0.316	0.000
M87.2 Osteonecrosis due to previous trauma	0.683	0.317	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.683	0.317	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.683	0.317	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.683	0.317	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.683	0.317	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.683	0.317	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.683	0.317	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.683	0.317	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.682	0.318	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.682	0.318	0.000
D05 Carcinoma in situ of breast	0.682	0.318	0.000
C45 Mesothelioma	0.682	0.318	0.000
S32 Fracture of lumbar spine and pelvis	0.681	0.319	0.000
M46.4 Discitis, unspecified	0.681	0.319	0.000
F38 Other mood [affective] disorders	0.681	0.319	0.000
F34 Persistent mood [affective] disorders	0.681	0.319	0.000
F30.0 Hypomania	0.681	0.319	0.000
N64.5 Other signs and symptoms in breast	0.680	0.320	0.000
M49 Spondylopathies in diseases classified elsewhere	0.679	0.321	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.677	0.323	0.000
G70-G73 Diseases of myoneural junction and muscle	0.677	0.323	0.000
M53 Other dorsopathies, not elsewhere classified	0.677	0.323	0.000
Q18 Other congenital malformations of face and neck	0.677	0.323	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.324	0.676
F45 Somatoform disorders	0.676	0.324	0.000
Chapter XXII Codes for special purposes	0.675	0.324	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.675	0.325	0.000
M65-M68 Disorders of synovium and tendon	0.674	0.326	0.000
N23 Unspecified renal colic	0.671	0.329	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.671	0.329	0.000
M86.9 Osteomyelitis, unspecified	0.668	0.332	0.000
Q00-Q07 Congenital malformations of the nervous system	0.668	0.332	0.000
G24.9 Dystonia, unspecified	0.666	0.333	0.000
F17.9 Unspecified mental and behavioural disorder	0.666	0.334	0.000
F17.8 Other mental and behavioural disorders	0.666	0.334	0.000
F17.7 Residual and late-onset psychotic disorder	0.666	0.334	0.000
F17.6 Amnesic syndrome	0.666	0.334	0.000
F17.5 Psychotic disorder	0.666	0.334	0.000
F17.4 Withdrawal state with delirium	0.666	0.334	0.000
F17.3 Withdrawal state	0.666	0.334	0.000
F17.0 Acute intoxication	0.666	0.334	0.000
E13.9 Without complications	0.000	0.337	0.663
Q60-Q64 Congenital malformations of the urinary system	0.663	0.337	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.663	0.337	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.337	0.663
E63 Other nutritional deficiencies	0.000	0.337	0.663
E56 Other vitamin deficiencies	0.000	0.337	0.663
E51 Thiamine deficiency	0.000	0.337	0.663
E50 Vitamin A deficiency	0.000	0.337	0.663
E60 Dietary zinc deficiency	0.000	0.337	0.663
E59 Dietary selenium deficiency	0.000	0.337	0.663
E58 Dietary calcium deficiency	0.000	0.337	0.663
E54 Ascorbic acid deficiency	0.000	0.337	0.663
E52 Niacin deficiency [pellagra]	0.000	0.337	0.663
F44 Dissociative [conversion] disorders	0.662	0.337	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.662	0.338	0.000
M90 Osteopathies in diseases classified elsewhere	0.661	0.339	0.000
M10 Gout	0.661	0.339	0.000
T36 Poisoning by systemic antibiotics	0.661	0.339	0.000
F41.9 Anxiety disorder, unspecified	0.659	0.341	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.659	0.341	0.000
S14 Injury of nerves and spinal cord at neck level	0.658	0.342	0.000
C32 Malignant neoplasm of larynx	0.657	0.343	0.000
F43 Reaction to severe stress, and adjustment disorders	0.655	0.345	0.000
F11.1 Harmful use	0.654	0.346	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.654	0.346	0.000
C34.2 Middle lobe, bronchus or lung	0.651	0.349	0.000
T33-T35 Frostbite	0.651	0.349	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.651	0.349	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.650	0.350	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.649	0.351	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.648	0.352	0.000
Q35-Q37 Cleft lip and cleft palate	0.648	0.352	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.648	0.352	0.000
N64.8 Other specified disorders of breast	0.647	0.353	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.647	0.353	0.000
F12.1 Harmful use	0.647	0.353	0.000
F30.9 Manic episode, unspecified	0.645	0.355	0.000
T16 Foreign body in ear	0.645	0.355	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.645	0.355	0.000
M42 Spinal osteochondrosis	0.643	0.356	0.000
M40 Kyphosis and lordosis	0.643	0.356	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.643	0.356	0.000
M11 Other crystal arthropathies	0.643	0.357	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.643	0.357	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.643	0.357	0.000
M47.84 Other spondylosis (Thoracic region)	0.643	0.357	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.643	0.357	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.643	0.357	0.000
E61 Deficiency of other nutrient elements	0.000	0.358	0.642
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.642	0.358	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.642	0.358	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.642	0.358	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.642	0.358	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.641	0.359	0.000
D06.9 Cervix, unspecified	0.640	0.360	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.360	0.640
M70-M79 Other soft tissue disorders	0.639	0.361	0.000
M87.9 Osteonecrosis, unspecified	0.639	0.361	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.639	0.361	0.000
F11.2 Dependence syndrome	0.638	0.362	0.000
N10 Acute tubulo-interstitial nephritis	0.638	0.362	0.000
M00 Pyogenic arthritis	0.638	0.362	0.000
S36 Injury of intra-abdominal organs	0.637	0.363	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.637	0.363	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.636	0.364	0.000
C65 Malignant neoplasm of renal pelvis	0.636	0.364	0.000
M89.3 Hypertrophy of bone	0.634	0.366	0.000
C01 Malignant neoplasm of base of tongue	0.632	0.368	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.631	0.369	0.000
F42 Obsessive-compulsive disorder	0.630	0.369	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.630	0.370	0.000
G30-G32 Other degenerative diseases of the nervous system	0.630	0.370	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.630	0.370	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.629	0.371	0.000
N21.8 Other lower urinary tract calculus	0.629	0.371	0.000
N21.1 Calculus in urethra	0.629	0.371	0.000
M87.8 Other osteonecrosis	0.628	0.372	0.000
E06.9 Thyroiditis, unspecified	0.000	0.373	0.627
L57.0 Actinic keratosis	0.626	0.374	0.000
Q78 Other osteochondrodysplasias	0.626	0.374	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.625	0.375	0.000
M92 Other juvenile osteochondrosis	0.624	0.376	0.000
C66 Malignant neoplasm of ureter	0.624	0.376	0.000
F48 Other neurotic disorders	0.623	0.377	0.000
F40 Phobic anxiety disorders	0.623	0.377	0.000
Chapter XX External causes of morbidity and mortality	0.622	0.378	0.000
C09 Malignant neoplasm of tonsil	0.622	0.378	0.000
T42.4 Benzodiazepines	0.621	0.379	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.621	0.379	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.620	0.380	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.619	0.381	0.000
S11 Open wound of neck	0.619	0.381	0.000
C91 Lymphoid leukaemia	0.618	0.381	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.618	0.382	0.000
M47.2 Other spondylosis with radiculopathy	0.618	0.382	0.000
S80 Superficial injury of lower leg	0.617	0.383	0.000
T19 Foreign body in genito-urinary tract	0.617	0.383	0.000
T15 Foreign body on external eye	0.617	0.383	0.000
M94 Other disorders of cartilage	0.617	0.383	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.616	0.384	0.000
M80-M85 Disorders of bone density and structure	0.615	0.385	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.615	0.385	0.000
M93 Other osteochondropathies	0.613	0.387	0.000
G24.3 Spasmodic torticollis	0.613	0.387	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.612	0.388	0.000
L60-L75 Disorders of skin appendages	0.612	0.388	0.000
C34.1 Upper lobe, bronchus or lung	0.610	0.390	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.609	0.390	0.000
W20-W49 Exposure to inanimate mechanical forces	0.609	0.391	0.000
M46.8 Other specified inflammatory spondylopathies	0.608	0.392	0.000
M46.5 Other infective spondylopathies	0.608	0.392	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.608	0.392	0.000
M46.2 Osteomyelitis of vertebra	0.608	0.392	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.608	0.392	0.000
M46.0 Spinal enthesopathy	0.608	0.392	0.000
C34.0 Main bronchus	0.608	0.392	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.608	0.392	0.000
S31.4 Open wound of vagina and vulva	0.607	0.392	0.000
E55.0 Rickets, active	0.000	0.393	0.607
S32.0 Fracture of lumbar vertebra	0.607	0.393	0.000
M43.0 Spondylolysis	0.606	0.394	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.606	0.394	0.000
S37 Injury of urinary and pelvic organs	0.606	0.394	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.606	0.394	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.606	0.394	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.606	0.394	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.605	0.395	0.000
F31.8 Other bipolar affective disorders	0.604	0.395	0.000
F31.7 Bipolar affective disorder, currently in remission	0.604	0.395	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.604	0.395	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.604	0.395	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.604	0.395	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.604	0.396	0.000
D45 Polycythaemia vera	0.604	0.396	0.000
S19 Other and unspecified injuries of neck	0.602	0.398	0.000
F30.8 Other manic episodes	0.602	0.398	0.000
F30.1 Mania without psychotic symptoms	0.602	0.398	0.000
E04 Other non-toxic goitre	0.000	0.399	0.601
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.601	0.399	0.000
C31 Malignant neoplasm of accessory sinuses	0.601	0.399	0.000
C37 Malignant neoplasm of thymus	0.601	0.399	0.000
C33 Malignant neoplasm of trachea	0.601	0.399	0.000
G37 Other demyelinating diseases of central nervous system	0.601	0.399	0.000
S10 Superficial injury of neck	0.600	0.399	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.600	0.400	0.000
D07.1 Vulva	0.600	0.400	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.600	0.400	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.599	0.401	0.000
E06.5 Other chronic thyroiditis	0.000	0.401	0.599
E06.4 Drug-induced thyroiditis	0.000	0.401	0.599
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.401	0.599
E06.1 Subacute thyroiditis	0.000	0.401	0.599
E06.0 Acute thyroiditis	0.000	0.401	0.599
M50.9 Cervical disk disorder, unspecified	0.599	0.401	0.000
T18.5 Foreign body in anus and rectum	0.598	0.402	0.000
B65-B83 Helminthiases	0.597	0.403	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.597	0.403	0.000
M50.0 Cervical disk disorder with myelopathy	0.595	0.405	0.000
G25 Other extrapyramidal and movement disorders	0.595	0.405	0.000
C34.3 Lower lobe, bronchus or lung	0.594	0.406	0.000
N99-N99 Other disorders of the genitourinary system	0.594	0.406	0.000
W22 Striking against or struck by other objects	0.593	0.407	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.593	0.407	0.000
T43.9 Psychotropic drug, unspecified	0.593	0.407	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.593	0.407	0.000
T43.6 Psychostimulants with abuse potential	0.593	0.407	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.593	0.407	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.592	0.408	0.000
M89.6 Osteopathy after poliomyelitis	0.591	0.409	0.000
M89.5 Osteolysis	0.591	0.409	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.591	0.409	0.000
M89.2 Other disorders of bone development and growth	0.591	0.409	0.000
M89.1 Epiphyseal arrest	0.591	0.409	0.000
M89.0 Algoneurodystrophy	0.591	0.409	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.591	0.409	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.591	0.409	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.590	0.410	0.000
M87.3 Other secondary osteonecrosis	0.590	0.410	0.000
M87.1 Osteonecrosis due to drugs	0.590	0.410	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.590	0.410	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.590	0.410	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.590	0.410	0.000
T42.3 Barbiturates	0.590	0.410	0.000
T42.2 Succinimides and oxazolidinediones	0.590	0.410	0.000
T42.1 Iminostilbenes	0.590	0.410	0.000
T42.0 Hydantoin derivatives	0.590	0.410	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.589	0.411	0.000
G62 Other polyneuropathies	0.588	0.412	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.587	0.413	0.000
A30-A49 Other bacterial diseases	0.586	0.413	0.000
S90-S99 Injuries to the ankle and foot	0.587	0.413	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.586	0.414	0.000
F50 Eating disorders	0.586	0.414	0.000
M77 Other enthesopathies	0.585	0.415	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.584	0.416	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.584	0.416	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.584	0.416	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.584	0.416	0.000
C05 Malignant neoplasm of palate	0.584	0.416	0.000
T45.0 Antiallergic and antiemetic drugs	0.583	0.417	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.583	0.417	0.000
Q80-Q89 Other congenital malformations	0.583	0.417	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.418	0.582
M43.9 Deforming dorsopathy, unspecified	0.582	0.418	0.000
M43.8 Other specified deforming dorsopathies	0.582	0.418	0.000
M43.6 Torticollis	0.582	0.418	0.000
M43.5 Other recurrent vertebral subluxation	0.582	0.418	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.582	0.418	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.582	0.418	0.000
M43.2 Other fusion of spine	0.582	0.418	0.000
A15-A19 Tuberculosis	0.582	0.418	0.000
T17.2 Foreign body in pharynx	0.582	0.418	0.000
W22.9 Unspecified place	0.582	0.418	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.581	0.418	0.000
L58 Radiodermatitis	0.581	0.418	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.581	0.418	0.000
L55 Sunburn	0.581	0.418	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.419	0.581
B25-B34 Other viral diseases	0.581	0.419	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.581	0.419	0.000
Q21 Congenital malformations of cardiac septa	0.580	0.419	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.420	0.580
G60 Hereditary and idiopathic neuropathy	0.580	0.420	0.000
D07.2 Vagina	0.578	0.421	0.000
M47.1 Other spondylosis with myelopathy	0.578	0.422	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.578	0.422	0.000
G40.9 Epilepsy, unspecified	0.577	0.423	0.000
E13.8 With unspecified complications	0.000	0.424	0.576
E13.7 With multiple complications	0.000	0.424	0.576
E13.6 With other specified complications	0.000	0.424	0.576
E13.5 With peripheral circulatory complications	0.000	0.424	0.576
E13.4 With neurological complications	0.000	0.424	0.576
E13.3 With ophthalmic complications	0.000	0.424	0.576
E13.2 With renal complications	0.000	0.424	0.576
E13.1 With ketoacidosis	0.000	0.424	0.576
E13.0 With coma	0.000	0.424	0.576
F11.9 Unspecified mental and behavioural disorder	0.576	0.424	0.000
F11.8 Other mental and behavioural disorders	0.576	0.424	0.000
F11.7 Residual and late-onset psychotic disorder	0.576	0.424	0.000
F11.6 Amnesic syndrome	0.576	0.424	0.000
F11.5 Psychotic disorder	0.576	0.424	0.000
F11.4 Withdrawal state with delirium	0.576	0.424	0.000
F11.3 Withdrawal state	0.576	0.424	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations