TreeWAS – Variant ID: rs1199333

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C50.3 Lower-inner quadrant of breast	0.324	0.676	0.000
C50 Malignant neoplasm of breast	0.323	0.677	0.000
C50.2 Upper-inner quadrant of breast	0.309	0.691	0.000
C50.1 Central portion of breast	0.304	0.696	0.000
C50.9 Breast, unspecified	0.300	0.700	0.000
C50.5 Lower-outer quadrant of breast	0.289	0.711	0.000
C50.6 Axillary tail of breast	0.231	0.769	0.000
C50.8 Overlapping lesion of breast	0.204	0.796	0.000
C50.0 Nipple and areola	0.200	0.800	0.000
C50-C50 Malignant neoplasm of breast	0.135	0.865	0.000
S01 Open wound of head	0.000	0.923	0.077
S01.8 Open wound of other parts of head	0.000	0.923	0.077
S01.0 Open wound of scalp	0.000	0.924	0.076
S01.5 Open wound of lip and oral cavity	0.000	0.927	0.073
S01.9 Open wound of head, part unspecified	0.000	0.930	0.070
C50.4 Upper-outer quadrant of breast	0.070	0.930	0.000
S01.4 Open wound of cheek and temporomandibular area	0.000	0.939	0.061
S01.1 Open wound of eyelid and periocular area	0.000	0.940	0.060
E04.2 Non-toxic multinodular goitre	0.046	0.954	0.000
S01.7 Multiple open wounds of head	0.000	0.956	0.043
S01.2 Open wound of nose	0.000	0.958	0.041
S01.3 Open wound of ear	0.000	0.963	0.037
S00-S09 Injuries to the head	0.000	0.974	0.026
S02 Fracture of skull and facial bones	0.000	0.974	0.026
S02.4 Fracture of malar and maxillary bones	0.000	0.976	0.024
S03 Dislocation, sprain and strain of joints and ligaments of head	0.000	0.977	0.023
S02.5 Fracture of tooth	0.000	0.977	0.023
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.978	0.022
S02.7 Multiple fractures involving skull and facial bones	0.000	0.979	0.021
S02.3 Fracture of orbital floor	0.000	0.979	0.021
S02.6 Fracture of mandible	0.000	0.980	0.020
S32 Fracture of lumbar spine and pelvis	0.020	0.980	0.000
S02.0 Fracture of vault of skull	0.000	0.980	0.020
S02.50 Fracture of tooth (closed)	0.000	0.980	0.020
S32.50 Fracture of pubis (closed)	0.020	0.980	0.000
S32.5 Fracture of pubis	0.020	0.980	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.980	0.020
S07 Crushing injury of head	0.000	0.981	0.019
S03.1 Dislocation of septal cartilage of nose	0.000	0.981	0.019
S32.0 Fracture of lumbar vertebra	0.019	0.981	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.981	0.019
S04 Injury of cranial nerves	0.000	0.981	0.019
S32.00 Fracture of lumbar vertebra (closed)	0.019	0.981	0.000
S08 Traumatic amputation of part of head	0.000	0.981	0.018
S32.7 Multiple fractures of lumbar spine and pelvis	0.018	0.982	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.982	0.018
S32.1 Fracture of sacrum	0.017	0.982	0.000
S03.0 Dislocation of jaw	0.000	0.983	0.017
S05 Injury of eye and orbit	0.000	0.983	0.017
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.983	0.017
S02.2 Fracture of nasal bones	0.000	0.983	0.017
S03.2 Dislocation of tooth	0.000	0.983	0.017
T79.7 Traumatic subcutaneous emphysema	0.000	0.983	0.017
S02.1 Fracture of base of skull	0.000	0.983	0.017
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.983	0.017
S02.30 Fracture of orbital floor (closed)	0.000	0.983	0.017
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.983	0.017
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.000	0.983	0.016
S03.4 Sprain and strain of jaw	0.000	0.983	0.016
S03.3 Dislocation of other and unspecified parts of head	0.000	0.983	0.016
S02.51 Fracture of tooth (open)	0.000	0.984	0.016
S32.3 Fracture of ilium	0.016	0.984	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.016	0.984	0.000
S02.60 Fracture of mandible (closed)	0.000	0.984	0.016
S32.10 Fracture of sacrum (closed)	0.016	0.984	0.000
S32.2 Fracture of coccyx	0.016	0.984	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.985	0.015
S02.00 Fracture of vault of skull (closed)	0.000	0.985	0.015
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.985	0.015
S02.31 Fracture of orbital floor (open)	0.000	0.985	0.015
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.985	0.015
S02.61 Fracture of mandible (open)	0.000	0.985	0.015
S02.01 Fracture of vault of skull (open)	0.000	0.985	0.015
T79.6 Traumatic ischaemia of muscle	0.000	0.985	0.015
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.986	0.014
S32.51 Fracture of pubis (open)	0.014	0.986	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.986	0.014
S07.9 Crushing injury of head, part unspecified	0.000	0.986	0.014
S07.8 Crushing injury of other parts of head	0.000	0.986	0.014
S07.1 Crushing injury of skull	0.000	0.986	0.014
S07.0 Crushing injury of face	0.000	0.986	0.014
S32.01 Fracture of lumbar vertebra (open)	0.014	0.986	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.986	0.014
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.986	0.014
S04.9 Injury of unspecified cranial nerve	0.000	0.986	0.014
S04.8 Injury of other cranial nerves	0.000	0.986	0.014
S04.7 Injury of accessory nerve	0.000	0.986	0.014
S04.6 Injury of acoustic nerve	0.000	0.986	0.014
S04.4 Injury of abducent nerve	0.000	0.986	0.014
S04.3 Injury of trigeminal nerve	0.000	0.986	0.014
S04.2 Injury of trochlear nerve	0.000	0.986	0.014
S04.1 Injury of oculomotor nerve	0.000	0.986	0.014
S04.0 Injury of optic nerve and pathways	0.000	0.986	0.014
S32.4 Fracture of acetabulum	0.014	0.986	0.000
S04.5 Injury of facial nerve	0.000	0.986	0.013
S08.9 Traumatic amputation of unspecified part of head	0.000	0.986	0.013
S08.8 Traumatic amputation of other parts of head	0.000	0.986	0.013
S08.0 Avulsion of scalp	0.000	0.986	0.013
S32.30 Fracture of ilium (closed)	0.013	0.986	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.986	0.013
S05.1 Contusion of eyeball and orbital tissues	0.000	0.987	0.013
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.013	0.987	0.000
S08.1 Traumatic amputation of ear	0.000	0.987	0.013
S32.11 Fracture of sacrum (open)	0.013	0.987	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.013	0.987	0.000
S05.7 Avulsion of eye	0.000	0.987	0.013
T79.4 Traumatic shock	0.000	0.987	0.013
S02.11 Fracture of base of skull (open)	0.000	0.987	0.012
T79.8 Other early complications of trauma	0.000	0.988	0.012
S32.20 Fracture of coccyx (closed)	0.012	0.988	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.988	0.012
T79.9 Unspecified early complication of trauma	0.000	0.988	0.012
T79.1 Fat embolism (traumatic)	0.000	0.988	0.012
T79.0 Air embolism (traumatic)	0.000	0.988	0.012
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.988	0.012
S32.31 Fracture of ilium (open)	0.012	0.988	0.000
T79.5 Traumatic anuria	0.000	0.988	0.012
S72.00 Fracture of neck of femur (closed)	0.000	0.988	0.012
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.012	0.988	0.000
S32.21 Fracture of coccyx (open)	0.011	0.989	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.989	0.011
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.989	0.011
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.011	0.989	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.989	0.011
S00 Superficial injury of head	0.000	0.989	0.011
S36 Injury of intra-abdominal organs	0.010	0.990	0.000
S05.9 Injury of eye and orbit, part unspecified	0.000	0.990	0.010
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.990	0.010
S32.41 Fracture of acetabulum (open)	0.010	0.990	0.000
S09 Other and unspecified injuries of head	0.000	0.990	0.010
S05.8 Other injuries of eye and orbit	0.000	0.990	0.010
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.010	0.990	0.000
M10.99 Gout, unspecified (Site unspecified)	0.000	0.990	0.010
S02.10 Fracture of base of skull (closed)	0.000	0.990	0.010
S00.7 Multiple superficial injuries of head	0.000	0.991	0.009
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.009	0.991	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.009	0.991	0.000
S36.8 Injury of other intra-abdominal organs	0.009	0.991	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.009	0.991	0.000
S32.40 Fracture of acetabulum (closed)	0.009	0.991	0.000
S72.0 Fracture of neck of femur	0.000	0.991	0.009
S06 Intracranial injury	0.000	0.991	0.009
S00.3 Superficial injury of nose	0.000	0.991	0.009
S36.4 Injury of small intestine	0.009	0.991	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.009	0.991	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.008	0.991	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.008	0.991	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.008	0.991	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.008	0.992	0.000
S37 Injury of urinary and pelvic organs	0.008	0.992	0.000
Z12 Special screening examination for neoplasms	0.008	0.992	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.008	0.992	0.000
S00.1 Contusion of eyelid and periocular area	0.000	0.992	0.008
S36.5 Injury of colon	0.008	0.992	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.008	0.992	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.008	0.992	0.000
S09.7 Multiple injuries of head	0.000	0.992	0.008
S36.0 Injury of spleen	0.008	0.992	0.000
Z12.3 Special screening examination for neoplasm of breast	0.008	0.992	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.008	0.992	0.000
S36.7 Injury of multiple intra-abdominal organs	0.008	0.992	0.000
S36.6 Injury of rectum	0.008	0.992	0.000
S36.3 Injury of stomach	0.008	0.992	0.000
S36.2 Injury of pancreas	0.008	0.992	0.000
S00.4 Superficial injury of ear	0.000	0.992	0.008
S35.2 Injury of coeliac or mesenteric artery	0.007	0.992	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.007	0.992	0.000
S09.1 Injury of muscle and tendon of head	0.000	0.992	0.007
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.007	0.993	0.000
S72 Fracture of femur	0.000	0.993	0.007
S36.40 Injury of small intestine (without open wound into cavity)	0.007	0.993	0.000
S00.0 Superficial injury of scalp	0.000	0.993	0.007
E04 Other non-toxic goitre	0.007	0.993	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.007	0.993	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.007	0.993	0.000
S00.5 Superficial injury of lip and oral cavity	0.000	0.993	0.007
S09.2 Traumatic rupture of ear drum	0.000	0.993	0.007
T79-T79 Certain early complications of trauma	0.000	0.993	0.007
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.993	0.007
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.007	0.993	0.000
S72.2 Subtrochanteric fracture	0.000	0.993	0.007
S33.1 Dislocation of lumbar vertebra	0.007	0.993	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.007	0.993	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.007	0.993	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.007	0.993	0.000
S35.5 Injury of iliac blood vessels	0.007	0.993	0.000
S35.4 Injury of renal blood vessels	0.007	0.993	0.000
S35.3 Injury of portal or splenic vein	0.007	0.993	0.000
S35.1 Injury of inferior vena cava	0.007	0.993	0.000
S35.0 Injury of abdominal aorta	0.007	0.993	0.000
S36.1 Injury of liver or gallbladder	0.007	0.993	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.993	0.007
S33.5 Sprain and strain of lumbar spine	0.007	0.993	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.993	0.007
S72.20 Subtrochanteric fracture (closed)	0.000	0.993	0.007
Z12.6 Special screening examination for neoplasm of bladder	0.007	0.993	0.000
S06.0 Concussion	0.000	0.993	0.007
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.006	0.993	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.006	0.993	0.000
S33.4 Traumatic rupture of symphysis pubis	0.006	0.993	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.006	0.993	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.006	0.993	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.006	0.993	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.006	0.993	0.000
S34.1 Other injury of lumbar spinal cord	0.006	0.993	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.006	0.994	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.006	0.994	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.006	0.994	0.000
S34.4 Injury of lumbosacral plexus	0.006	0.994	0.000
S34.3 Injury of cauda equina	0.006	0.994	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.006	0.994	0.000
S06.1 Traumatic cerebral oedema	0.000	0.994	0.006
S06.2 Diffuse brain injury	0.000	0.994	0.006
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.006	0.994	0.000
S38.2 Traumatic amputation of external genital organs	0.006	0.994	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.006	0.994	0.000
S38.0 Crushing injury of external genital organs	0.006	0.994	0.000
S72.1 Pertrochanteric fracture	0.000	0.994	0.006
S06.4 Epidural haemorrhage	0.000	0.994	0.006
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.006	0.994	0.000
S36.50 Injury of colon (without open wound into cavity)	0.006	0.994	0.000
S06.3 Focal brain injury	0.000	0.994	0.006
S72.3 Fracture of shaft of femur	0.000	0.994	0.006
S31 Open wound of abdomen, lower back and pelvis	0.006	0.994	0.000
S37.9 Injury of unspecified pelvic organ	0.006	0.994	0.000
S37.8 Injury of other pelvic organs	0.006	0.994	0.000
S37.7 Injury of multiple pelvic organs	0.006	0.994	0.000
S37.6 Injury of uterus	0.006	0.994	0.000
S37.5 Injury of Fallopian tube	0.006	0.994	0.000
S37.4 Injury of ovary	0.006	0.994	0.000
S37.2 Injury of bladder	0.006	0.994	0.000
S37.1 Injury of ureter	0.006	0.994	0.000
S37.0 Injury of kidney	0.006	0.994	0.000
S06.8 Other intracranial injuries	0.000	0.994	0.006
S09.8 Other specified injuries of head	0.000	0.994	0.006
Z12.2 Special screening examination for neoplasm of respiratory organs	0.006	0.994	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.006	0.994	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.994	0.006
S36.51 Injury of colon (with open wound into cavity)	0.006	0.994	0.000
S37.3 Injury of urethra	0.006	0.994	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.006	0.994	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.994	0.006
S36.21 Injury of pancreas (with open wound into cavity)	0.006	0.994	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.006	0.994	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.006	0.994	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.006	0.994	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.006	0.994	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.006	0.994	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.006	0.994	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.006	0.994	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.006	0.994	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.006	0.994	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.006	0.994	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.994	0.006
S06.9 Intracranial injury, unspecified	0.000	0.994	0.005
S72.4 Fracture of lower end of femur	0.000	0.994	0.006
T42.4 Benzodiazepines	0.006	0.994	0.000
N64.5 Other signs and symptoms in breast	0.006	0.994	0.000
S72.7 Multiple fractures of femur	0.000	0.994	0.005
E04.8 Other specified non-toxic goitre	0.005	0.995	0.000
Z45.1 Adjustment and management of infusion pump	0.000	0.995	0.005
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.995	0.005
S00.8 Superficial injury of other parts of head	0.000	0.995	0.005
S72.9 Fracture of femur, part unspecified	0.000	0.995	0.005
T50.9 Other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
S72.21 Subtrochanteric fracture (open)	0.000	0.995	0.005
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.005	0.995	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.995	0.005
S72.8 Fractures of other parts of femur	0.000	0.995	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.005	0.995	0.000
G20 Parkinson's disease	0.000	0.995	0.005
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.995	0.005
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.995	0.005
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
S06.01 Concussion (with open intracranial wound)	0.000	0.995	0.005
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.995	0.005
S31.0 Open wound of lower back and pelvis	0.005	0.995	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.995	0.005
S72.31 Fracture of shaft of femur (open)	0.000	0.995	0.005
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.995	0.005
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.005	0.995	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.995	0.005
S72.11 Pertrochanteric fracture (open)	0.000	0.995	0.005
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.995	0.005
E04.9 Non-toxic goitre, unspecified	0.005	0.995	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.995	0.004
S31.5 Open wound of other and unspecified external genital organs	0.004	0.995	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.004	0.995	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.004	0.995	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.004	0.995	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.004	0.995	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.004	0.995	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.004	0.995	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.004	0.995	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.004	0.995	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.004	0.995	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.004	0.995	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.004	0.995	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.004	0.995	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.004	0.995	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.004	0.995	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.004	0.995	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.004	0.995	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.004	0.995	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.995	0.004
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.995	0.004
S37.00 Injury of kidney (without open wound into cavity)	0.004	0.995	0.000
M10.9 Gout, unspecified	0.000	0.995	0.005
S31.8 Open wound of other and unspecified parts of abdomen	0.004	0.995	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.995	0.004
T42.0 Hydantoin derivatives	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.995	0.004
S31.2 Open wound of penis	0.004	0.995	0.000
S37.31 Injury of urethra (with open wound into cavity)	0.004	0.995	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.995	0.000
Z48.8 Other specified surgical follow-up care	0.005	0.995	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.996	0.004
Z42.1 Follow-up care involving plastic surgery of breast	0.004	0.996	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.996	0.004
E04.0 Non-toxic diffuse goitre	0.004	0.996	0.000
S31.4 Open wound of vagina and vulva	0.004	0.996	0.000
T46.1 Calcium-channel blockers	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
S31.3 Open wound of scrotum and testes	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.996	0.004
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.004	0.996	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.004	0.996	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.996	0.004
M10.96 Gout, unspecified (Lower leg)	0.000	0.996	0.004
T42.1 Iminostilbenes	0.004	0.996	0.000
S72.70 Multiple fractures of femur (closed)	0.000	0.996	0.004
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.996	0.004
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.996	0.004
S72.41 Fracture of lower end of femur (open)	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
S72.91 Fracture of femur, part unspecified (open)	0.000	0.996	0.004
S72.81 Fractures of other parts of femur (open)	0.000	0.996	0.004
T40.5 Cocaine	0.004	0.996	0.000
T40.1 Heroin	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
T46.7 Peripheral vasodilators	0.004	0.996	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.996	0.004
S00.9 Superficial injury of head, part unspecified	0.000	0.996	0.004
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.996	0.004
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T40.2 Other opioids	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.996	0.003
S82.50 Fracture of medial malleolus (closed)	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
S30.2 Contusion of external genital organs	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.996	0.000
D34 Benign neoplasm of thyroid gland	0.000	0.996	0.004
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.004	0.996	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.004	0.996	0.000
M10.98 Gout, unspecified (Other)	0.000	0.996	0.003
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.996	0.003
M10.91 Gout, unspecified (Shoulder region)	0.000	0.996	0.003
S72.80 Fractures of other parts of femur (closed)	0.000	0.996	0.003
T45.2 Vitamins, not elsewhere classified	0.004	0.996	0.000
D13.1 Stomach	0.000	0.996	0.004
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.996	0.000
T40.8 Lysergide [LSD]	0.003	0.996	0.000
T40.7 Cannabis (derivatives)	0.003	0.996	0.000
T40.3 Methadone	0.003	0.996	0.000
T40.0 Opium	0.003	0.996	0.000
T36.0 Penicillins	0.003	0.996	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
M10.92 Gout, unspecified (Upper arm)	0.000	0.997	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
N64.1 Fat necrosis of breast	0.003	0.997	0.000
Z04.9 Examination and observation for unspecified reason	0.003	0.997	0.000
S09.9 Unspecified injury of head	0.000	0.997	0.003
M10.90 Gout, unspecified (Multiple sites)	0.000	0.997	0.003
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
N64 Other disorders of breast	0.003	0.997	0.000
S31.1 Open wound of abdominal wall	0.003	0.997	0.001
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
M10.94 Gout, unspecified (Hand)	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.997	0.003
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
G20-G26 Extrapyramidal and movement disorders	0.000	0.997	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
O00.1 Tubal pregnancy	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
G25 Other extrapyramidal and movement disorders	0.000	0.997	0.003
Q65.8 Other congenital deformities of hip	0.000	0.997	0.003
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.997	0.003
N64.4 Mastodynia	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
G25.0 Essential tremor	0.000	0.997	0.003
S30.0 Contusion of lower back and pelvis	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
G25.5 Other chorea	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
G21 Secondary Parkinsonism	0.000	0.997	0.003
N64.2 Atrophy of breast	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations