TreeWAS – Variant ID: rs12046289

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
S00-S09 Injuries to the head	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000
E03 Other hypothyroidism	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000
E10.9 Without complications	0.999	0.001
# Top node	0.999	0.001
M05-M14 Inflammatory polyarthropathies	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.998	0.002
S02 Fracture of skull and facial bones	0.998	0.002
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
S06 Intracranial injury	0.996	0.004
E10.1 With ketoacidosis	0.996	0.004
Chapter X Diseases of the respiratory system	0.995	0.005
J20-J22 Other acute lower respiratory infections	0.988	0.012
M75.0 Adhesive capsulitis of shoulder	0.984	0.016
S09 Other and unspecified injuries of head	0.982	0.018
M75 Shoulder lesions	0.982	0.018
M70-M79 Other soft tissue disorders	0.981	0.019
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.980	0.020
J22 Unspecified acute lower respiratory infection	0.978	0.022
S01 Open wound of head	0.976	0.024
E05 Thyrotoxicosis [hyperthyroidism]	0.974	0.026
S00 Superficial injury of head	0.969	0.031
Chapter V Mental and behavioural disorders	0.968	0.032
E16 Other disorders of pancreatic internal secretion	0.967	0.033
F10 Mental and behavioural disorders due to use of alcohol	0.966	0.034
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.964	0.036
F10.1 Harmful use	0.960	0.040
S06.2 Diffuse brain injury	0.958	0.042
E16.2 Hypoglycaemia, unspecified	0.957	0.043
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.953	0.047
M75.2 Bicipital tendinitis	0.952	0.048
S09.9 Unspecified injury of head	0.952	0.048
E05.9 Thyrotoxicosis, unspecified	0.952	0.048
E70-E90 Metabolic disorders	0.951	0.049
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.946	0.054
E10.5 With peripheral circulatory complications	0.945	0.055
S00.8 Superficial injury of other parts of head	0.944	0.056
S00.0 Superficial injury of scalp	0.939	0.061
J95-J99 Other diseases of the respiratory system	0.938	0.062
M06.0 Seronegative rheumatoid arthritis	0.935	0.065
S06.20 Diffuse brain injury (without open intracranial wound)	0.931	0.069
S02.3 Fracture of orbital floor	0.925	0.075
J86 Pyothorax	0.924	0.076
F10.0 Acute intoxication	0.922	0.078
E87 Other disorders of fluid, electrolyte and acid-base balance	0.920	0.080
S40-S49 Injuries to the shoulder and upper arm	0.919	0.081
S02.0 Fracture of vault of skull	0.917	0.083
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.917	0.083
S20-S29 Injuries to the thorax	0.914	0.086
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.910	0.090
E10.3 With ophthalmic complications	0.909	0.091
J86.9 Pyothorax without fistula	0.907	0.093
S06.5 Traumatic subdural haemorrhage	0.907	0.093
S01.9 Open wound of head, part unspecified	0.907	0.093
S02.2 Fracture of nasal bones	0.906	0.094
E65-E68 Obesity and other hyperalimentation	0.901	0.099
E89.0 Postprocedural hypothyroidism	0.901	0.099
S01.2 Open wound of nose	0.893	0.107
M60-M63 Disorders of muscles	0.892	0.108
M86-M90 Other osteopathies	0.888	0.112
E87.2 Acidosis	0.888	0.112
J99 Respiratory disorders in diseases classified elsewhere	0.888	0.112
J60-J70 Lung diseases due to external agents	0.876	0.124
E40-E46 Malnutrition	0.874	0.126
S02.30 Fracture of orbital floor (closed)	0.874	0.126
S01.0 Open wound of scalp	0.873	0.127
E87.5 Hyperkalaemia	0.872	0.128
S06.6 Traumatic subarachnoid haemorrhage	0.870	0.130
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.867	0.133
S01.5 Open wound of lip and oral cavity	0.866	0.134
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.862	0.138
T20-T25 Burns and corrosions of external body surface, specified by site	0.861	0.139
E10.0 With coma	0.861	0.139
S02.00 Fracture of vault of skull (closed)	0.859	0.141
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.859	0.141
J99.8 Respiratory disorders in other diseases classified elsewhere	0.856	0.144
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.851	0.149
S10-S19 Injuries to the neck	0.847	0.153
E03.8 Other specified hypothyroidism	0.843	0.157
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.843	0.157
S02.1 Fracture of base of skull	0.842	0.158
S02.20 Fracture of nasal bones (closed)	0.840	0.160
M07 Psoriatic and enteropathic arthropathies	0.838	0.162
Q20-Q28 Congenital malformations of the circulatory system	0.832	0.168
E66 Obesity	0.831	0.169
E85 Amyloidosis	0.829	0.171
S05 Injury of eye and orbit	0.827	0.173
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.825	0.175
S09.2 Traumatic rupture of ear drum	0.822	0.178
M06.8 Other specified rheumatoid arthritis	0.821	0.179
T00-T07 Injuries involving multiple body regions	0.821	0.179
F10.4 Withdrawal state with delirium	0.820	0.180
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.815	0.185
S00.5 Superficial injury of lip and oral cavity	0.814	0.186
S41 Open wound of shoulder and upper arm	0.813	0.187
F10.9 Unspecified mental and behavioural disorder	0.807	0.193
F10.6 Amnesic syndrome	0.807	0.193
M75.5 Bursitis of shoulder	0.806	0.194
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.804	0.196
J20 Acute bronchitis	0.799	0.201
M06.98 Rheumatoid arthritis, unspecified (Other)	0.799	0.201
S06.3 Focal brain injury	0.799	0.201
E10.8 With unspecified complications	0.798	0.202
S02.4 Fracture of malar and maxillary bones	0.797	0.203
M62 Other disorders of muscle	0.796	0.204
J90-J94 Other diseases of pleura	0.792	0.208
E10.6 With other specified complications	0.791	0.209
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.789	0.211
M76 Enthesopathies of lower limb, excluding foot	0.788	0.212
M86 Osteomyelitis	0.787	0.213
S06.0 Concussion	0.785	0.215
S21 Open wound of thorax	0.785	0.215
E46 Unspecified protein-energy malnutrition	0.784	0.216
E87.7 Fluid overload	0.782	0.218
S02.7 Multiple fractures involving skull and facial bones	0.781	0.219
E88 Other metabolic disorders	0.781	0.219
S09.0 Injury of blood vessels of head, not elsewhere classified	0.781	0.219
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.780	0.220
E10.4 With neurological complications	0.774	0.226
M06.3 Rheumatoid nodule	0.771	0.229
Q80-Q89 Other congenital malformations	0.771	0.229
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.770	0.230
J21 Acute bronchiolitis	0.769	0.231
S27 Injury of other and unspecified intrathoracic organs	0.769	0.231
S06.4 Epidural haemorrhage	0.766	0.234
E02 Subclinical iodine-deficiency hypothyroidism	0.764	0.236
M12 Other specific arthropathies	0.763	0.237
E66.9 Obesity, unspecified	0.763	0.237
Q50-Q56 Congenital malformations of genital organs	0.763	0.237
F20 Schizophrenia	0.762	0.238
S50-S59 Injuries to the elbow and forearm	0.761	0.239
S43.4 Sprain and strain of shoulder joint	0.761	0.239
S49 Other and unspecified injuries of shoulder and upper arm	0.758	0.242
E20-E35 Disorders of other endocrine glands	0.756	0.244
D50-D53 Nutritional anaemias	0.755	0.245
F14 Mental and behavioural disorders due to use of cocaine	0.752	0.247
J92 Pleural plaque	0.752	0.248
S43.0 Dislocation of shoulder joint	0.752	0.248
E10.2 With renal complications	0.751	0.249
S06.8 Other intracranial injuries	0.747	0.253
E84 Cystic fibrosis	0.746	0.254
Q00-Q07 Congenital malformations of the nervous system	0.746	0.254
J69 Pneumonitis due to solids and liquids	0.745	0.255
S02.9 Fracture of skull and facial bones, part unspecified	0.741	0.259
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.740	0.260
E06 Thyroiditis	0.740	0.260
S90-S99 Injuries to the ankle and foot	0.738	0.262
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.732	0.268
M91-M94 Chondropathies	0.731	0.269
S02.10 Fracture of base of skull (closed)	0.730	0.270
J98 Other respiratory disorders	0.729	0.271
S02.5 Fracture of tooth	0.727	0.273
E85.4 Organ-limited amyloidosis	0.726	0.274
E05.0 Thyrotoxicosis with diffuse goitre	0.726	0.274
M07.3 Other psoriatic arthropathies	0.723	0.277
D51 Vitamin B12 deficiency anaemia	0.723	0.277
T66-T78 Other and unspecified effects of external causes	0.722	0.278
S00.4 Superficial injury of ear	0.722	0.278
S02.8 Fractures of other skull and facial bones	0.721	0.279
E66.8 Other obesity	0.721	0.279
F70-F79 Mental retardation	0.720	0.280
M90 Osteopathies in diseases classified elsewhere	0.717	0.283
J92.9 Pleural plaque without asbestos	0.717	0.283
E10.7 With multiple complications	0.717	0.283
S08 Traumatic amputation of part of head	0.717	0.283
S07 Crushing injury of head	0.717	0.283
S04 Injury of cranial nerves	0.717	0.283
S03 Dislocation, sprain and strain of joints and ligaments of head	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283
E00 Congenital iodine-deficiency syndrome	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
M06.2 Rheumatoid bursitis	0.717	0.283
M06.1 Adult-onset Still's disease	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
M09 Juvenile arthritis in diseases classified elsewhere	0.716	0.284
M08 Juvenile arthritis	0.716	0.284
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.715	0.285
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
E16.1 Other hypoglycaemia	0.715	0.285
Q38-Q45 Other congenital malformations of the digestive system	0.714	0.286
S06.7 Intracranial injury with prolonged coma	0.714	0.286
S06.1 Traumatic cerebral oedema	0.714	0.286
D80-D89 Certain disorders involving the immune mechanism	0.714	0.286
S02.6 Fracture of mandible	0.714	0.286
Q24 Other congenital malformations of heart	0.714	0.286
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.709	0.291
I80 Phlebitis and thrombophlebitis	0.708	0.292
S29 Other and unspecified injuries of thorax	0.705	0.295
S09.7 Multiple injuries of head	0.704	0.296
S09.1 Injury of muscle and tendon of head	0.704	0.296
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.704	0.296
M75.8 Other shoulder lesions	0.704	0.296
T00 Superficial injuries involving multiple body regions	0.704	0.296
M73 Soft tissue disorders in diseases classified elsewhere	0.703	0.297
E15 Nondiabetic hypoglycaemic coma	0.703	0.297
Q25 Congenital malformations of great arteries	0.703	0.297
Chapter IX Diseases of the circulatory system	0.701	0.299
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.700	0.300
M86.9 Osteomyelitis, unspecified	0.700	0.300
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.700	0.300
T14 Injury of unspecified body region	0.699	0.301
S22 Fracture of rib(s), sternum and thoracic spine	0.699	0.301
S41.0 Open wound of shoulder	0.699	0.301
E05.5 Thyroid crisis or storm	0.698	0.302
E05.4 Thyrotoxicosis factitia	0.698	0.302
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.698	0.302
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.698	0.302
M40-M43 Deforming dorsopathies	0.696	0.304
S09.8 Other specified injuries of head	0.696	0.304
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.694	0.306
M60 Myositis	0.693	0.307
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.693	0.307
E16.9 Disorder of pancreatic internal secretion, unspecified	0.693	0.307
E16.8 Other specified disorders of pancreatic internal secretion	0.693	0.307
E16.4 Abnormal secretion of gastrin	0.693	0.307
E16.3 Increased secretion of glucagon	0.693	0.307
M80-M85 Disorders of bone density and structure	0.693	0.307
F10.8 Other mental and behavioural disorders	0.692	0.307
F10.7 Residual and late-onset psychotic disorder	0.692	0.307
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.691	0.309
F18 Mental and behavioural disorders due to use of volatile solvents	0.691	0.309
F16 Mental and behavioural disorders due to use of hallucinogens	0.691	0.309
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.691	0.309
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.691	0.309
E89.3 Postprocedural hypopituitarism	0.691	0.309
S01.4 Open wound of cheek and temporomandibular area	0.691	0.309
E11 Non-insulin-dependent diabetes mellitus	0.689	0.311
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.689	0.311
M62.8 Other specified disorders of muscle	0.688	0.312
J64 Unspecified pneumoconiosis	0.687	0.312
E79 Disorders of purine and pyrimidine metabolism	0.687	0.312
S06.21 Diffuse brain injury (with open intracranial wound)	0.687	0.313
M00-M03 Infectious arthropathies	0.686	0.313
M88 Paget's disease of bone [osteitis deformans]	0.687	0.313
S05.9 Injury of eye and orbit, part unspecified	0.685	0.315
F20.9 Schizophrenia, unspecified	0.685	0.315
Chapter I Certain infectious and parasitic diseases	0.682	0.318
E77 Disorders of glycoprotein metabolism	0.682	0.318
E76 Disorders of glycosaminoglycan metabolism	0.682	0.318
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.682	0.318
E72 Other disorders of amino-acid metabolism	0.682	0.318
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.682	0.318
E70 Disorders of aromatic amino-acid metabolism	0.682	0.318
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.682	0.318
F10.5 Psychotic disorder	0.681	0.319
S43.1 Dislocation of acromioclavicular joint	0.680	0.320
E87.3 Alkalosis	0.680	0.320
Q35-Q37 Cleft lip and cleft palate	0.678	0.321
Q30-Q34 Congenital malformations of the respiratory system	0.678	0.321
E05.8 Other thyrotoxicosis	0.678	0.322
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.677	0.323
T20 Burn and corrosion of head and neck	0.676	0.324
F11 Mental and behavioural disorders due to use of opioids	0.675	0.325
F60-F69 Disorders of adult personality and behaviour	0.674	0.326
S10 Superficial injury of neck	0.674	0.326
E23 Hypofunction and other disorders of pituitary gland	0.674	0.326
J20.9 Acute bronchitis, unspecified	0.674	0.326
J85 Abscess of lung and mediastinum	0.673	0.327
S01.8 Open wound of other parts of head	0.673	0.327
J96 Respiratory failure, not elsewhere classified	0.673	0.327
T21 Burn and corrosion of trunk	0.671	0.329
M06.08 Seronegative rheumatoid arthritis (Other)	0.671	0.329
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.671	0.329
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.671	0.329
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.671	0.329
M06.04 Seronegative rheumatoid arthritis (Hand)	0.671	0.329
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.671	0.329
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.671	0.329
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.671	0.329
J60 Coalworker's pneumoconiosis	0.669	0.331
M05 Seropositive rheumatoid arthritis	0.669	0.331
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.668	0.331
F25 Schizoaffective disorders	0.668	0.332
Q21 Congenital malformations of cardiac septa	0.667	0.333
J09-J18 Influenza and pneumonia	0.666	0.334
I83 Varicose veins of lower extremities	0.665	0.335
E16.0 Drug-induced hypoglycaemia without coma	0.665	0.335
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.664	0.336
S02.31 Fracture of orbital floor (open)	0.663	0.336
S99 Other and unspecified injuries of ankle and foot	0.663	0.337
J95 Postprocedural respiratory disorders, not elsewhere classified	0.663	0.337
S41.1 Open wound of upper arm	0.660	0.339
E87.4 Mixed disorder of acid-base balance	0.659	0.340
S48 Traumatic amputation of shoulder and upper arm	0.659	0.341
S45 Injury of blood vessels at shoulder and upper arm level	0.659	0.341
S44 Injury of nerves at shoulder and upper arm level	0.659	0.341
S47 Crushing injury of shoulder and upper arm	0.659	0.341
S02.01 Fracture of vault of skull (open)	0.657	0.342
S06.30 Focal brain injury (without open intracranial wound)	0.657	0.343
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.657	0.343
E89.8 Other postprocedural endocrine and metabolic disorders	0.657	0.343
E89.5 Postprocedural testicular hypofunction	0.657	0.343
E89.4 Postprocedural ovarian failure	0.657	0.343
E89.1 Postprocedural hypoinsulinaemia	0.657	0.343
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.656	0.344
S26 Injury of heart	0.656	0.344
S25 Injury of blood vessels of thorax	0.656	0.344
S24 Injury of nerves and spinal cord at thorax level	0.656	0.344
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.656	0.344
S21.9 Open wound of thorax, part unspecified	0.654	0.346
S02.40 Fracture of malar and maxillary bones (closed)	0.654	0.346
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.652	0.348
J69.0 Pneumonitis due to food and vomit	0.652	0.348
S14 Injury of nerves and spinal cord at neck level	0.651	0.349
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.650	0.350
M62.6 Muscle strain	0.650	0.350
B90-B94 Sequelae of infectious and parasitic diseases	0.650	0.350
S02.21 Fracture of nasal bones (open)	0.649	0.351
E11.1 With ketoacidosis	0.649	0.351
M06.4 Inflammatory polyarthropathy	0.649	0.351
I87 Other disorders of veins	0.649	0.351
F80-F89 Disorders of psychological development	0.649	0.351
M92 Other juvenile osteochondrosis	0.648	0.352
M76.6 Achilles tendinitis	0.647	0.353
J70 Respiratory conditions due to other external agents	0.647	0.353
E67 Other hyperalimentation	0.646	0.354
E68 Sequelae of hyperalimentation	0.646	0.354
J67 Hypersensitivity pneumonitis due to organic dust	0.644	0.356
E65 Localised adiposity	0.644	0.356
E23.0 Hypopituitarism	0.643	0.357
F22 Persistent delusional disorders	0.643	0.357
M10 Gout	0.641	0.359
M63 Disorders of muscle in diseases classified elsewhere	0.640	0.360
M61 Calcification and ossification of muscle	0.640	0.360
M75.9 Shoulder lesion, unspecified	0.639	0.361
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.639	0.361
S19 Other and unspecified injuries of neck	0.635	0.365
D50 Iron deficiency anaemia	0.634	0.366
S06.00 Concussion (without open intracranial wound)	0.634	0.366
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.631	0.369
M85 Other disorders of bone density and structure	0.631	0.369
M86.8 Other osteomyelitis	0.630	0.369
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.630	0.370
E85.9 Amyloidosis, unspecified	0.629	0.371
S05.8 Other injuries of eye and orbit	0.629	0.371
S21.1 Open wound of front wall of thorax	0.629	0.371
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.628	0.372
J66 Airway disease due to specific organic dust	0.628	0.372
J63 Pneumoconiosis due to other inorganic dusts	0.628	0.372
J62 Pneumoconiosis due to dust containing silica	0.628	0.372
J65 Pneumoconiosis associated with tuberculosis	0.628	0.372
E20 Hypoparathyroidism	0.628	0.372
E44 Protein-energy malnutrition of moderate and mild degree	0.627	0.373
E45 Retarded development following protein-energy malnutrition	0.627	0.373
E43 Unspecified severe protein-energy malnutrition	0.627	0.373
E42 Marasmic kwashiorkor	0.627	0.373
E41 Nutritional marasmus	0.627	0.373
E40 Kwashiorkor	0.627	0.373
S02.70 Multiple fractures involving skull and facial bones (closed)	0.626	0.374
F40-F48 Neurotic, stress-related and somatoform disorders	0.625	0.375
S56 Injury of muscle and tendon at forearm level	0.625	0.375
S12 Fracture of neck	0.625	0.375
Q07 Other congenital malformations of nervous system	0.624	0.376
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.624	0.376
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.624	0.376
B91 Sequelae of poliomyelitis	0.624	0.376
S06.9 Intracranial injury, unspecified	0.623	0.377
E13 Other specified diabetes mellitus	0.621	0.378
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.621	0.379
S43.6 Sprain and strain of sternoclavicular joint	0.621	0.379
S43.5 Sprain and strain of acromioclavicular joint	0.621	0.379
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.621	0.379
S43.2 Dislocation of sternoclavicular joint	0.621	0.379
M87 Osteonecrosis	0.621	0.379
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.620	0.380
J99.0 Rheumatoid lung disease	0.619	0.381
J98.5 Diseases of mediastinum, not elsewhere classified	0.619	0.381
S00.3 Superficial injury of nose	0.618	0.382
T25 Burn and corrosion of ankle and foot	0.618	0.382
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.618	0.382
E74 Other disorders of carbohydrate metabolism	0.616	0.384
S27.0 Traumatic pneumothorax	0.616	0.384
B35-B49 Mycoses	0.614	0.385
S27.2 Traumatic heamopneumothorax	0.614	0.386
S59 Other and unspecified injuries of forearm	0.614	0.386
M13 Other arthritis	0.613	0.387
E06.3 Autoimmune thyroiditis	0.613	0.387
Q38 Other congenital malformations of tongue, mouth and pharynx	0.613	0.387
J21.9 Acute bronchiolitis, unspecified	0.612	0.388
I83.1 Varicose veins of lower extremities with inflammation	0.612	0.388
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.611	0.389
D84 Other immunodeficiencies	0.611	0.389
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.611	0.389
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.611	0.389
S49.9 Unspecified injury of shoulder and upper arm	0.610	0.390
F28 Other nonorganic psychotic disorders	0.610	0.390
F24 Induced delusional disorder	0.610	0.390
F21 Schizotypal disorder	0.610	0.390
M62.88 Other specified disorders of muscle (Other)	0.610	0.390
D50.8 Other iron deficiency anaemias	0.608	0.392
S17 Crushing injury of neck	0.607	0.393
S15 Injury of blood vessels at neck level	0.607	0.393
S18 Traumatic amputation at neck level	0.607	0.393
S16 Injury of muscle and tendon at neck level	0.607	0.393
M06.34 Rheumatoid nodule (Hand)	0.607	0.393
Q27 Other congenital malformations of peripheral vascular system	0.607	0.393
M85.6 Other cyst of bone	0.605	0.395
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.604	0.396
S02.11 Fracture of base of skull (open)	0.603	0.396
M75.3 Calcific tendinitis of shoulder	0.604	0.396
I05-I09 Chronic rheumatic heart diseases	0.603	0.397
E26 Hyperaldosteronism	0.603	0.397
S20 Superficial injury of thorax	0.601	0.399
M07.6 Other enteropathic arthropathies	0.601	0.399
M07.5 Arthropathy in ulcerative colitis	0.601	0.399
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.601	0.399
M07.2 Psoriatic spondylitis	0.601	0.399
M07.1 Arthritis mutilans	0.601	0.399
M07.0 Distal interphalangeal psoriatic arthropathy	0.601	0.399
F14.1 Harmful use	0.601	0.399
S06.40 Epidural haemorrhage (without open intracranial wound)	0.601	0.399
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.600	0.400
E84.9 Cystic fibrosis, unspecified	0.599	0.401
J86.0 Pyothorax with fistula	0.599	0.401
M11 Other crystal arthropathies	0.598	0.402
Chapter XXII Codes for special purposes	0.597	0.403
T14.9 Injury, unspecified	0.597	0.403
Q26 Congenital malformations of great veins	0.597	0.403
Q22 Congenital malformations of pulmonary and tricuspid valves	0.597	0.403
Q20 Congenital malformations of cardiac chambers and connexions	0.597	0.403
E85.3 Secondary systemic amyloidosis	0.597	0.403
E66.1 Drug-induced obesity	0.596	0.404
M12.2 Villonodular synovitis (pigmented)	0.595	0.405
E85.8 Other amyloidosis	0.594	0.405
E85.2 Heredofamilial amyloidosis, unspecified	0.594	0.405
E85.1 Neuropathic heredofamilial amyloidosis	0.594	0.405
E85.0 Nonneuropathic heredofamilial amyloidosis	0.594	0.405
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.593	0.407
M07.39 Other psoriatic arthropathies (Site unspecified)	0.593	0.407
S05.7 Avulsion of eye	0.593	0.407
S05.6 Penetrating wound of eyeball without foreign body	0.593	0.407
S05.5 Penetrating wound of eyeball with foreign body	0.593	0.407
S05.4 Penetrating wound of orbit with or without foreign body	0.593	0.407
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.593	0.407
Q53 Undescended testicle	0.593	0.407
B44 Aspergillosis	0.593	0.407
E66.2 Extreme obesity with alveolar hypoventilation	0.592	0.408
I85 Oesophageal varices	0.591	0.409
M90.7 Fracture of bone in neoplastic disease	0.591	0.409
M07.30 Other psoriatic arthropathies (Multiple sites)	0.590	0.410
S49.8 Other specified injuries of shoulder and upper arm	0.590	0.410
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.589	0.411
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.589	0.411
M06.88 Other specified rheumatoid arthritis (Other)	0.589	0.411
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.589	0.411
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.589	0.411
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.589	0.411
M06.84 Other specified rheumatoid arthritis (Hand)	0.589	0.411
M06.83 Other specified rheumatoid arthritis (Forearm)	0.589	0.411
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.589	0.411
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.589	0.411
T06 Other injuries involving multiple body regions, not elsewhere classified	0.588	0.411
T05 Traumatic amputations involving multiple body regions	0.588	0.411
T04 Crushing injuries involving multiple body regions	0.588	0.411
T03 Dislocations, sprains and strains involving multiple body regions	0.588	0.411
T01 Open wounds involving multiple body regions	0.588	0.411
T07 Unspecified multiple injuries	0.588	0.411
S51 Open wound of forearm	0.588	0.412
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.587	0.413
S27.1 Traumatic haemothorax	0.587	0.413
S22.0 Fracture of thoracic vertebra	0.587	0.413
T09 Other injuries of spine and trunk, level unspecified	0.586	0.413
E24 Cushing's syndrome	0.586	0.414
J98.8 Other specified respiratory disorders	0.586	0.414
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.585	0.415
T78 Adverse effects, not elsewhere classified	0.585	0.415
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.584	0.416
F20.0 Paranoid schizophrenia	0.584	0.416
Q24.0 Dextrocardia	0.583	0.417
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.583	0.417
S41.7 Multiple open wounds of shoulder and upper arm	0.583	0.417
I83.0 Varicose veins of lower extremities with ulcer	0.582	0.418
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.582	0.418
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.582	0.418
Q83 Congenital malformations of breast	0.581	0.419
M14 Arthropathies in other diseases classified elsewhere	0.580	0.419
E11.0 With coma	0.580	0.420
T15-T19 Effects of foreign body entering through natural orifice	0.580	0.420
J94 Other pleural conditions	0.580	0.420
J92.0 Pleural plaque with presence of asbestos	0.580	0.420
F12 Mental and behavioural disorders due to use of cannabinoids	0.579	0.421
T79-T79 Certain early complications of trauma	0.578	0.422
M62.86 Other specified disorders of muscle (Lower leg)	0.578	0.422
F29 Unspecified nonorganic psychosis	0.578	0.422
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.578	0.422

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations