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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12074980
log Bayes Factor = 15.0721
Chromosome 1   position 184,636,516  (GRCh37) Explore rs12074980 on Ensembl!
Variant rs12074980 is part of Cluster X0139

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.994 0.006 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.987 0.013 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.981 0.019 0.000
Z50 Care involving use of rehabilitation procedures
0.981 0.019 0.000
Chapter X Diseases of the respiratory system
0.980 0.020 0.000
I95 Hypotension
0.978 0.022 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.978 0.022 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.977 0.023 0.000
D50-D53 Nutritional anaemias
0.971 0.029 0.000
I30-I52 Other forms of heart disease
0.965 0.035 0.000
Chapter I Certain infectious and parasitic diseases
0.964 0.036 0.000
M05-M14 Inflammatory polyarthropathies
0.962 0.038 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.961 0.039 0.000
T81 Complications of procedures, not elsewhere classified
0.955 0.045 0.000
I95.9 Hypotension, unspecified
0.944 0.056 0.000
Z50.1 Other physical therapy
0.944 0.056 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.943 0.057 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.942 0.058 0.000
B95-B98 Bacterial, viral and other infectious agents
0.941 0.059 0.000
I60-I69 Cerebrovascular diseases
0.931 0.069 0.000
H25-H28 Disorders of lens
0.927 0.073 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.926 0.074 0.000
D51 Vitamin B12 deficiency anaemia
0.924 0.076 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.922 0.078 0.000
M50-M54 Other dorsopathies
0.922 0.078 0.000
Z04 Examination and observation for other reasons
0.920 0.080 0.000
Z47 Other orthopaedic follow-up care
0.913 0.087 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.913 0.087 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.910 0.090 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.908 0.092 0.000
I20-I25 Ischaemic heart diseases
0.907 0.093 0.000
Z13 Special screening examination for other diseases and disorders
0.900 0.100 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.899 0.101 0.000
M06 Other rheumatoid arthritis
0.894 0.106 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.890 0.110 0.000
Y86 Sequelae of other accidents
0.886 0.114 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.885 0.115 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.884 0.116 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.881 0.119 0.000
J40-J47 Chronic lower respiratory diseases
0.880 0.120 0.000
I47 Paroxysmal tachycardia
0.879 0.121 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.876 0.124 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.875 0.125 0.000
I95.1 Orthostatic hypotension
0.872 0.128 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.872 0.128 0.000
R42 Dizziness and giddiness
0.870 0.130 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.869 0.131 0.000
Chapter XI Diseases of the digestive system
0.869 0.131 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.867 0.132 0.000
H04 Disorders of lachrymal system
0.861 0.139 0.000
D50 Iron deficiency anaemia
0.861 0.139 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.857 0.143 0.000
J45 Asthma
0.857 0.143 0.000
M10 Gout
0.857 0.143 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.856 0.144 0.000
I25 Chronic ischaemic heart disease
0.854 0.146 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.851 0.149 0.000
E70-E90 Metabolic disorders
0.849 0.151 0.000
M54 Dorsalgia
0.849 0.151 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.848 0.152 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.846 0.154 0.000
M06.9 Rheumatoid arthritis, unspecified
0.846 0.154 0.000
J45.9 Asthma, unspecified
0.845 0.155 0.000
D69 Purpura and other haemorrhagic conditions
0.845 0.155 0.000
I95.2 Hypotension due to drugs
0.842 0.158 0.000
S80-S89 Injuries to the knee and lower leg
0.839 0.161 0.000
Z04.8 Examination and observation for other specified reasons
0.839 0.161 0.000
I44 Atrioventricular and left bundle-branch block
0.834 0.166 0.000
H02 Other disorders of eyelid
0.833 0.167 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.832 0.168 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.828 0.172 0.000
I67 Other cerebrovascular diseases
0.826 0.174 0.000
J00-J06 Acute upper respiratory infections
0.825 0.175 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.825 0.175 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.825 0.175 0.000
I10-I15 Hypertensive diseases
0.824 0.176 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.824 0.176 0.000
I34 Nonrheumatic mitral valve disorders
0.823 0.177 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.822 0.178 0.000
Chapter XXII Codes for special purposes
0.822 0.178 0.000
J60-J70 Lung diseases due to external agents
0.822 0.178 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.821 0.179 0.000
D50.8 Other iron deficiency anaemias
0.820 0.180 0.000
T66-T78 Other and unspecified effects of external causes
0.817 0.183 0.000
Z50.0 Cardiac rehabilitation
0.816 0.184 0.000
H25 Senile cataract
0.815 0.185 0.000
H26 Other cataract
0.814 0.186 0.000
Z40 Prophylactic surgery
0.813 0.187 0.000
K50-K52 Noninfective enteritis and colitis
0.811 0.189 0.000
R20 Disturbances of skin sensation
0.809 0.191 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.809 0.191 0.000
I05-I09 Chronic rheumatic heart diseases
0.806 0.194 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.803 0.196 0.000
H04.2 Epiphora
0.802 0.198 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.801 0.199 0.000
Z47.8 Other specified orthopaedic follow-up care
0.800 0.199 0.000
Z13.9 Special screening examination, unspecified
0.800 0.200 0.000
J81 Pulmonary oedema
0.798 0.202 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.797 0.203 0.000
T93 Sequelae of injuries of lower limb
0.790 0.210 0.000
H25.1 Senile nuclear cataract
0.789 0.211 0.000
Z03.8 Observation for other suspected diseases and conditions
0.788 0.212 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.788 0.212 0.000
T51 Toxic effect of alcohol
0.788 0.212 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.784 0.216 0.000
I20 Angina pectoris
0.783 0.217 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.783 0.217 0.000
E86 Volume depletion
0.783 0.217 0.000
J95-J99 Other diseases of the respiratory system
0.783 0.217 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.782 0.218 0.000
M10.9 Gout, unspecified
0.782 0.218 0.000
M51 Other intervertebral disk disorders
0.781 0.219 0.000
M80-M85 Disorders of bone density and structure
0.780 0.220 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.779 0.221 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.779 0.221 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.779 0.221 0.000
S40-S49 Injuries to the shoulder and upper arm
0.779 0.221 0.000
I47.1 Supraventricular tachycardia
0.779 0.221 0.000
H02.4 Ptosis of eyelid
0.777 0.223 0.000
M86-M90 Other osteopathies
0.776 0.224 0.000
J30-J39 Other diseases of upper respiratory tract
0.774 0.226 0.000
H10-H13 Disorders of conjunctiva
0.773 0.226 0.000
R47-R49 Symptoms and signs involving speech and voice
0.772 0.228 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.772 0.228 0.000
I71 Aortic aneurysm and dissection
0.771 0.229 0.000
E83 Disorders of mineral metabolism
0.768 0.232 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.768 0.232 0.000
H55-H59 Other disorders of eye and adnexa
0.767 0.233 0.000
I49 Other cardiac arrhythmias
0.767 0.233 0.000
M07 Psoriatic and enteropathic arthropathies
0.766 0.234 0.000
Chapter V Mental and behavioural disorders
0.766 0.234 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.766 0.234 0.000
V20-V29 Motorcycle rider injured in transport accident
0.763 0.237 0.000
H43-H45 Disorders of vitreous body and globe
0.763 0.237 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.763 0.237 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.763 0.237 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.762 0.238 0.000
I62 Other nontraumatic intracranial haemorrhage
0.761 0.239 0.000
K50 Crohn's disease [regional enteritis]
0.761 0.239 0.000
S60-S69 Injuries to the wrist and hand
0.760 0.240 0.000
D69.6 Thrombocytopenia, unspecified
0.760 0.240 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.760 0.240 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.759 0.240 0.000
D80-D89 Certain disorders involving the immune mechanism
0.759 0.241 0.000
M13 Other arthritis
0.756 0.244 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.756 0.244 0.000
A00-A09 Intestinal infectious diseases
0.756 0.244 0.000
K70-K77 Diseases of liver
0.754 0.246 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.754 0.246 0.000
H26.9 Cataract, unspecified
0.754 0.246 0.000
H53-H54 Visual disturbances and blindness
0.754 0.246 0.000
Z52 Donors of organs and tissues
0.751 0.249 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.750 0.250 0.000
Y88 Sequelae of surgical and medical care as external cause
0.750 0.250 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.750 0.250 0.000
I20.0 Unstable angina
0.749 0.251 0.000
S20-S29 Injuries to the thorax
0.748 0.252 0.000
M45-M49 Spondylopathies
0.748 0.252 0.000
M54.5 Low back pain
0.747 0.253 0.000
D68 Other coagulation defects
0.747 0.253 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.745 0.255 0.000
Z04.9 Examination and observation for unspecified reason
0.744 0.256 0.000
I34.0 Mitral (valve) insufficiency
0.744 0.256 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.743 0.257 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.742 0.258 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.742 0.258 0.000
X60-X84 Intentional self-harm
0.740 0.260 0.000
I38 Endocarditis, valve unspecified
0.740 0.260 0.000
E50-E64 Other nutritional deficiencies
0.737 0.263 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.736 0.264 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.736 0.264 0.000
W20-W49 Exposure to inanimate mechanical forces
0.736 0.264 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.734 0.266 0.000
Z49 Care involving dialysis
0.734 0.266 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.734 0.266 0.000
I44.7 Left bundle-branch block, unspecified
0.732 0.268 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.731 0.268 0.000
R45 Symptoms and signs involving emotional state
0.731 0.269 0.000
T43.2 Other and unspecified antidepressants
0.729 0.271 0.000
I67.9 Cerebrovascular disease, unspecified
0.729 0.271 0.000
Z51 Other medical care
0.729 0.271 0.000
Z43 Attention to artificial openings
0.728 0.272 0.000
I10 Essential (primary) hypertension
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.726 0.274 0.000
T39.0 Salicylates
0.725 0.274 0.000
S70-S79 Injuries to the hip and thigh
0.725 0.275 0.000
I46 Cardiac arrest
0.725 0.275 0.000
Z04.3 Examination and observation following other accident
0.724 0.276 0.000
T51.0 Ethanol
0.724 0.276 0.000
I33 Acute and subacute endocarditis
0.724 0.276 0.000
I44.1 Atrioventricular block, second degree
0.723 0.277 0.000
Y84.8 Other medical procedures
0.722 0.277 0.000
I73 Other peripheral vascular diseases
0.722 0.278 0.000
R30-R39 Symptoms and signs involving the urinary system
0.722 0.278 0.000
Z53.8 Procedure not carried out for other reasons
0.721 0.279 0.000
K40-K46 Hernia
0.720 0.280 0.000
D52 Folate deficiency anaemia
0.720 0.280 0.000
E20-E35 Disorders of other endocrine glands
0.720 0.280 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.716 0.284 0.000
H00 Hordeolum and chalazion
0.716 0.284 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.713 0.287 0.000
Z54 Convalescence
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.712 0.288 0.000
M10.99 Gout, unspecified (Site unspecified)
0.712 0.288 0.000
I63 Cerebral infarction
0.712 0.288 0.000
E83.1 Disorders of iron metabolism
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.710 0.290 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.709 0.290 0.000
I61 Intracerebral haemorrhage
0.709 0.291 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.708 0.292 0.000
I99 Other and unspecified disorders of circulatory system
0.708 0.292 0.000
R79 Other abnormal findings of blood chemistry
0.708 0.292 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.706 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.706 0.293 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.706 0.293 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.706 0.293 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.706 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.706 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.706 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.706 0.293 0.000
T36 Poisoning by systemic antibiotics
0.706 0.293 0.000
Y85 Sequelae of transport accidents
0.705 0.295 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.705 0.295 0.000
T39.1 4-Aminophenol derivatives
0.704 0.296 0.000
M91-M94 Chondropathies
0.704 0.296 0.000
M60-M63 Disorders of muscles
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.704 0.296 0.000
Z50.6 Orthoptic training
0.704 0.296 0.000
Z50.5 Speech therapy
0.704 0.296 0.000
Z50.3 Drug rehabilitation
0.704 0.296 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.702 0.298 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.702 0.298 0.000
I95.8 Other hypotension
0.701 0.298 0.000
I95.0 Idiopathic hypotension
0.701 0.298 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.702 0.298 0.000
Z10 Routine general health check-up of defined subpopulation
0.701 0.299 0.000
T87 Complications peculiar to reattachment and amputation
0.701 0.299 0.000
T86 Failure and rejection of transplanted organs and tissues
0.701 0.299 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.701 0.299 0.000
S50-S59 Injuries to the elbow and forearm
0.700 0.300 0.000
K86 Other diseases of pancreas
0.700 0.300 0.000
B35-B49 Mycoses
0.699 0.300 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.699 0.301 0.000
K51 Ulcerative colitis
0.699 0.301 0.000
D60-D64 Aplastic and other anaemias
0.699 0.301 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.699 0.301 0.000
M15-M19 Arthrosis
0.698 0.302 0.000
J09-J18 Influenza and pneumonia
0.698 0.302 0.000
Z50.2 Alcohol rehabilitation
0.698 0.302 0.000
Y57 Other and unspecified drugs and medicaments
0.698 0.302 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.698 0.302 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.698 0.302 0.000
D53 Other nutritional anaemias
0.696 0.304 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.695 0.305 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.694 0.306 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.694 0.306 0.000
M05 Seropositive rheumatoid arthritis
0.694 0.306 0.000
A30-A49 Other bacterial diseases
0.694 0.306 0.000
E65-E68 Obesity and other hyperalimentation
0.693 0.307 0.000
K85 Acute pancreatitis
0.693 0.307 0.000
T92 Sequelae of injuries of upper limb
0.692 0.308 0.000
I52 Other heart disorders in diseases classified elsewhere
0.692 0.308 0.000
I48 Atrial fibrillation and flutter
0.692 0.308 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.692 0.308 0.000
I41 Myocarditis in diseases classified elsewhere
0.692 0.308 0.000
I40 Acute myocarditis
0.692 0.308 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.692 0.308 0.000
I37 Pulmonary valve disorders
0.692 0.308 0.000
I36 Nonrheumatic tricuspid valve disorders
0.692 0.308 0.000
I32 Pericarditis in diseases classified elsewhere
0.692 0.308 0.000
I30 Acute pericarditis
0.692 0.308 0.000
B99-B99 Other infectious diseases
0.691 0.308 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.691 0.308 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.691 0.308 0.000
B65-B83 Helminthiases
0.691 0.308 0.000
B50-B64 Protozoal diseases
0.691 0.308 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.691 0.308 0.000
B15-B19 Viral hepatitis
0.691 0.308 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.691 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.308 0.000
A75-A79 Rickettsioses
0.691 0.308 0.000
A70-A74 Other diseases caused by chlamydiae
0.691 0.308 0.000
A65-A69 Other spirochaetal diseases
0.691 0.308 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.691 0.308 0.000
A20-A28 Certain zoonotic bacterial diseases
0.691 0.308 0.000
A15-A19 Tuberculosis
0.691 0.308 0.000
R20.2 Paraesthesia of skin
0.691 0.309 0.000
I50 Heart failure
0.690 0.309 0.000
M14 Arthropathies in other diseases classified elsewhere
0.690 0.310 0.000
M12 Other specific arthropathies
0.690 0.310 0.000
M11 Other crystal arthropathies
0.690 0.310 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.690 0.310 0.000
M08 Juvenile arthritis
0.690 0.310 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.689 0.311 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.689 0.311 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.689 0.311 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.689 0.311 0.000
H30-H36 Disorders of choroid and retina
0.688 0.312 0.000
Y43 Primarily systemic agents
0.688 0.312 0.000
J84 Other interstitial pulmonary diseases
0.688 0.312 0.000
K83 Other diseases of biliary tract
0.687 0.313 0.000
F30-F39 Mood [affective] disorders
0.687 0.313 0.000
Z12 Special screening examination for neoplasms
0.686 0.314 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.686 0.314 0.000
T81.9 Unspecified complication of procedure
0.685 0.315 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.685 0.315 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.685 0.315 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.685 0.315 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.685 0.315 0.000
I35 Nonrheumatic aortic valve disorders
0.685 0.315 0.000
K82 Other diseases of gallbladder
0.684 0.316 0.000
M54.9 Dorsalgia, unspecified
0.684 0.316 0.000
Z22 Carrier of infectious disease
0.683 0.317 0.000
H02.1 Ectropion of eyelid
0.683 0.317 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.683 0.317 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.680 0.320 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.680 0.320 0.000
I25.3 Aneurysm of heart
0.679 0.321 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.679 0.321 0.000
Z45 Adjustment and management of implanted device
0.679 0.321 0.000
I42 Cardiomyopathy
0.678 0.322 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.676 0.324 0.000
H05 Disorders of orbit
0.676 0.324 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.676 0.324 0.000
Y89 Sequelae of other external causes
0.675 0.325 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.675 0.325 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.674 0.325 0.000
I72 Other aneurysm
0.673 0.326 0.000
J00 Acute nasopharyngitis [common cold]
0.671 0.329 0.000
I08 Multiple valve diseases
0.670 0.330 0.000
M65-M68 Disorders of synovium and tendon
0.670 0.330 0.000
E00-E07 Disorders of thyroid gland
0.668 0.332 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.667 0.333 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.667 0.333 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.665 0.335 0.000
J46 Status asthmaticus
0.665 0.335 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.665 0.335 0.000
H27 Other disorders of lens
0.665 0.335 0.000
I47.2 Ventricular tachycardia
0.664 0.335 0.000
R46 Symptoms and signs involving appearance and behaviour
0.664 0.336 0.000
R43 Disturbances of smell and taste
0.664 0.336 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.663 0.337 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.663 0.337 0.000
D51.2 Transcobalamin II deficiency
0.663 0.337 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.663 0.337 0.000
T68 Hypothermia
0.663 0.337 0.000
H50 Other strabismus
0.662 0.337 0.000
J35 Chronic diseases of tonsils and adenoids
0.662 0.338 0.000
I67.1 Cerebral aneurysm, nonruptured
0.662 0.338 0.000
D67 Hereditary factor IX deficiency
0.661 0.339 0.000
D66 Hereditary factor VIII deficiency
0.661 0.339 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.661 0.339 0.000
M53 Other dorsopathies, not elsewhere classified
0.661 0.339 0.000
Y83.8 Other surgical procedures
0.660 0.340 0.000
I60 Subarachnoid haemorrhage
0.660 0.340 0.000
Z04.6 General psychiatric examination, requested by authority
0.660 0.340 0.000
Z04.5 Examination and observation following other inflicted injury
0.660 0.340 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.660 0.340 0.000
Z04.2 Examination and observation following work accident
0.660 0.340 0.000
Z04.1 Examination and observation following transport accident
0.660 0.340 0.000
Z04.0 Blood-alcohol and blood-drug test
0.660 0.340 0.000
M40-M43 Deforming dorsopathies
0.659 0.340 0.000
R04 Haemorrhage from respiratory passages
0.660 0.340 0.000
K75 Other inflammatory liver diseases
0.659 0.341 0.000
K50.1 Crohn's disease of large intestine
0.659 0.341 0.000
M54.56 Low back pain (Lumbar region)
0.658 0.342 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.658 0.342 0.000
Y83.3 Surgical operation with formation of external stoma
0.656 0.344 0.000
V10-V19 Pedal cyclist injured in transport accident
0.655 0.345 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.655 0.345 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.654 0.345 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.654 0.345 0.000
T39.4 Antirheumatics, not elsewhere classified
0.654 0.345 0.000
T39.2 Pyrazolone derivatives
0.654 0.345 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.654 0.346 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.654 0.346 0.000
K50.9 Crohn's disease, unspecified
0.654 0.346 0.000
Z51.2 Other chemotherapy
0.653 0.347 0.000
E40-E46 Malnutrition
0.653 0.347 0.000
S64 Injury of nerves at wrist and hand level
0.652 0.348 0.000
J32 Chronic sinusitis
0.652 0.348 0.000
I23 Certain current complications following acute myocardial infarction
0.650 0.350 0.000
J02 Acute pharyngitis
0.650 0.350 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.650 0.350 0.000
S81 Open wound of lower leg
0.650 0.350 0.000
I31 Other diseases of pericardium
0.649 0.351 0.000
I71.0 Dissection of aorta [any part]
0.649 0.351 0.000
K42 Umbilical hernia
0.649 0.351 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.647 0.353 0.000
H02.5 Other disorders affecting eyelid function
0.647 0.353 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.647 0.353 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.646 0.353 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.646 0.354 0.000
M54.2 Cervicalgia
0.646 0.354 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.645 0.355 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.645 0.355 0.000
Z13.5 Special screening examination for eye and ear disorders
0.645 0.355 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.645 0.355 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.645 0.355 0.000
Z13.2 Special screening examination for nutritional disorders
0.645 0.355 0.000
Z13.1 Special screening examination for diabetes mellitus
0.645 0.355 0.000
Z51.8 Other specified medical care
0.644 0.356 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.644 0.356 0.000
R73 Elevated blood glucose level
0.642 0.358 0.000
A08 Viral and other specified intestinal infections
0.642 0.358 0.000
R47 Speech disturbances, not elsewhere classified
0.642 0.358 0.000
M51.2 Other specified intervertebral disk displacement
0.642 0.358 0.000
M06.8 Other specified rheumatoid arthritis
0.641 0.359 0.000
M06.4 Inflammatory polyarthropathy
0.641 0.359 0.000
M06.3 Rheumatoid nodule
0.641 0.359 0.000
M06.2 Rheumatoid bursitis
0.641 0.359 0.000
M06.1 Adult-onset Still's disease
0.641 0.359 0.000
M06.0 Seronegative rheumatoid arthritis
0.641 0.359 0.000
R40 Somnolence, stupor and coma
0.641 0.359 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.640 0.360 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.640 0.360 0.000
M50 Cervical disk disorders
0.639 0.361 0.000
H52 Disorders of refraction and accommodation
0.639 0.361 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.639 0.361 0.000
S89 Other and unspecified injuries of lower leg
0.638 0.362 0.000
T98 Sequelae of other and unspecified effects of external causes
0.638 0.362 0.000
T95 Sequelae of burns, corrosions and frostbite
0.638 0.362 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.638 0.362 0.000
T91 Sequelae of injuries of neck and trunk
0.638 0.362 0.000
T90 Sequelae of injuries of head
0.638 0.362 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.638 0.362 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.638 0.362 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.638 0.362 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.638 0.362 0.000
B25-B34 Other viral diseases
0.638 0.362 0.000
R76 Other abnormal immunological findings in serum
0.637 0.363 0.000
J69 Pneumonitis due to solids and liquids
0.636 0.364 0.000
M54.3 Sciatica
0.636 0.364 0.000
S40 Superficial injury of shoulder and upper arm
0.636 0.364 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.634 0.366 0.000
J80 Adult respiratory distress syndrome
0.634 0.366 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.634 0.366 0.000
S80 Superficial injury of lower leg
0.634 0.366 0.000
Y84.0 Cardiac catheterisation
0.633 0.367 0.000
K70 Alcoholic liver disease
0.632 0.368 0.000
Z50.8 Care involving use of rehabilitation procedures
0.632 0.368 0.000
T43.9 Psychotropic drug, unspecified
0.632 0.368 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
T43.6 Psychostimulants with abuse potential
0.632 0.368 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.632 0.368 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.632 0.368 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.632 0.368 0.000
J41 Simple and mucopurulent chronic bronchitis
0.631 0.369 0.000
J42 Unspecified chronic bronchitis
0.631 0.369 0.000
Z48 Other surgical follow-up care
0.630 0.370 0.000
I47.0 Reentry ventricular arrhythmia
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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