TreeWAS – Variant ID: rs12185265

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C34.9 Bronchus or lung, unspecified	0.084	0.916	0.000
C34 Malignant neoplasm of bronchus and lung	0.063	0.937	0.000
C34.3 Lower lobe, bronchus or lung	0.062	0.938	0.000
C34.2 Middle lobe, bronchus or lung	0.052	0.948	0.000
C34.8 Overlapping lesion of bronchus and lung	0.047	0.952	0.000
K75.8 Other specified inflammatory liver diseases	0.043	0.957	0.000
C34.0 Main bronchus	0.030	0.970	0.000
K75 Other inflammatory liver diseases	0.027	0.973	0.000
K75.4 Autoimmune hepatitis	0.025	0.975	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.977	0.023
N93.8 Other specified abnormal uterine and vaginal bleeding	0.023	0.977	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.023	0.977	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.980	0.020
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.020	0.980	0.000
K75.2 Nonspecific reactive hepatitis	0.019	0.980	0.000
K75.1 Phlebitis of portal vein	0.019	0.980	0.000
E27.1 Primary adrenocortical insufficiency	0.018	0.982	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.017	0.983	0.000
C34.1 Upper lobe, bronchus or lung	0.017	0.983	0.000
C38.4 Pleura	0.016	0.984	0.000
G95.2 Cord compression, unspecified	0.016	0.984	0.000
C31 Malignant neoplasm of accessory sinuses	0.015	0.984	0.000
C33 Malignant neoplasm of trachea	0.015	0.985	0.000
S00.0 Superficial injury of scalp	0.015	0.985	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.014	0.985	0.000
K75.9 Inflammatory liver disease, unspecified	0.014	0.986	0.000
C37 Malignant neoplasm of thymus	0.013	0.987	0.000
I44.0 Atrioventricular block, first degree	0.013	0.987	0.000
K75.0 Abscess of liver	0.013	0.987	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.013	0.987	0.000
C38.2 Posterior mediastinum	0.013	0.987	0.000
C38.1 Anterior mediastinum	0.013	0.987	0.000
C38.0 Heart	0.013	0.987	0.000
C31.0 Maxillary sinus	0.012	0.988	0.000
C38.3 Mediastinum, part unspecified	0.012	0.988	0.000
G91.9 Hydrocephalus, unspecified	0.012	0.988	0.000
F25.9 Schizoaffective disorder, unspecified	0.012	0.988	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.011	0.988	0.000
C31.9 Accessory sinus, unspecified	0.011	0.989	0.000
C31.8 Overlapping lesion of accessory sinuses	0.011	0.989	0.000
C31.3 Sphenoidal sinus	0.011	0.989	0.000
C31.2 Frontal sinus	0.011	0.989	0.000
C31.1 Ethmoidal sinus	0.011	0.989	0.000
E27 Other disorders of adrenal gland	0.011	0.989	0.000
C39.9 Ill-defined sites within the respiratory system	0.011	0.989	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.011	0.989	0.000
C39.0 Upper respiratory tract, part unspecified	0.011	0.989	0.000
E27.2 Addisonian crisis	0.010	0.990	0.000
F25 Schizoaffective disorders	0.010	0.990	0.000
E27.8 Other specified disorders of adrenal gland	0.010	0.990	0.000
N93 Other abnormal uterine and vaginal bleeding	0.009	0.991	0.000
K50.1 Crohn's disease of large intestine	0.009	0.991	0.000
K74 Fibrosis and cirrhosis of liver	0.009	0.991	0.000
K74.6 Other and unspecified cirrhosis of liver	0.009	0.991	0.000
E27.9 Disorder of adrenal gland, unspecified	0.009	0.991	0.000
K70-K77 Diseases of liver	0.009	0.991	0.000
C30.1 Middle ear	0.008	0.991	0.000
F25.1 Schizoaffective disorder, depressive type	0.009	0.991	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.008	0.992	0.000
E27.5 Adrenomedullary hyperfunction	0.008	0.992	0.000
E27.0 Other adrenocortical overactivity	0.008	0.992	0.000
F25.0 Schizoaffective disorder, manic type	0.008	0.992	0.000
C32 Malignant neoplasm of larynx	0.008	0.992	0.000
E04.9 Non-toxic goitre, unspecified	0.008	0.992	0.000
K73 Chronic hepatitis, not elsewhere classified	0.008	0.992	0.000
K74.5 Biliary cirrhosis, unspecified	0.008	0.992	0.000
F25.2 Schizoaffective disorder, mixed type	0.007	0.992	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.007	0.992	0.000
F25.8 Other schizoaffective disorders	0.007	0.993	0.000
K71 Toxic liver disease	0.007	0.993	0.000
Z98.1 Arthrodesis status	0.000	0.993	0.007
K74.3 Primary biliary cirrhosis	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.993	0.000
F29 Unspecified nonorganic psychosis	0.007	0.993	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.007	0.993	0.000
C18.0 Caecum	0.007	0.993	0.000
N93.0 Postcoital and contact bleeding	0.007	0.993	0.000
K74.4 Secondary biliary cirrhosis	0.007	0.993	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.007	0.993	0.000
K73.9 Chronic hepatitis, unspecified	0.007	0.993	0.000
K74.1 Hepatic sclerosis	0.006	0.993	0.000
K77 Liver disorders in diseases classified elsewhere	0.006	0.993	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.993	0.006
S72.10 Pertrochanteric fracture (closed)	0.006	0.994	0.000
E87.7 Fluid overload	0.006	0.994	0.000
K71.0 Toxic liver disease with cholestasis	0.006	0.994	0.000
C32.8 Overlapping lesion of larynx	0.006	0.994	0.000
C32.3 Laryngeal cartilage	0.006	0.994	0.000
C32.2 Subglottis	0.006	0.994	0.000
G95 Other diseases of spinal cord	0.006	0.994	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.006	0.994	0.000
G91 Hydrocephalus	0.006	0.994	0.000
D10.3 Other and unspecified parts of mouth	0.000	0.994	0.006
Q50.4 Embryonic cyst of Fallopian tube	0.006	0.994	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.006	0.994	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.006	0.994	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.006	0.994	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.006	0.994	0.000
K71.9 Toxic liver disease, unspecified	0.006	0.994	0.000
C30.0 Nasal cavity	0.005	0.994	0.001
K74.0 Hepatic fibrosis	0.006	0.994	0.000
H35.0 Background retinopathy and retinal vascular changes	0.006	0.994	0.000
K71.8 Toxic liver disease with other disorders of liver	0.005	0.994	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.005	0.994	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.005	0.994	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.005	0.994	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.005	0.994	0.000
K71.2 Toxic liver disease with acute hepatitis	0.005	0.994	0.000
C32.9 Larynx, unspecified	0.005	0.995	0.000
F22.0 Delusional disorder	0.000	0.995	0.005
G95.9 Disease of spinal cord, unspecified	0.005	0.995	0.000
Z31.4 Procreative investigation and testing	0.005	0.995	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.005	0.995	0.000
E10.9 Without complications	0.005	0.995	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.005	0.995	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
D10.1 Tongue	0.000	0.995	0.005
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.995	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.005	0.995	0.000
S00 Superficial injury of head	0.005	0.995	0.000
C32.0 Glottis	0.005	0.995	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
F22 Persistent delusional disorders	0.003	0.995	0.002
D10 Benign neoplasm of mouth and pharynx	0.000	0.995	0.005
E10.5 With peripheral circulatory complications	0.005	0.995	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.004	0.995	0.000
Q54.9 Hypospadias, unspecified	0.005	0.995	0.000
F28 Other nonorganic psychotic disorders	0.004	0.995	0.000
F24 Induced delusional disorder	0.004	0.995	0.000
F21 Schizotypal disorder	0.004	0.995	0.000
G91.0 Communicating hydrocephalus	0.005	0.995	0.000
L05 Pilonidal cyst	0.000	0.995	0.005
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.005	0.995	0.000
D10.0 Lip	0.000	0.996	0.004
S00.9 Superficial injury of head, part unspecified	0.004	0.996	0.000
E10.4 With neurological complications	0.004	0.996	0.000
Z31 Procreative management	0.004	0.996	0.000
Z31.2 In vitro fertilisation	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
G91.2 Normal-pressure hydrocephalus	0.004	0.996	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.996	0.004
E10 Insulin-dependent diabetes mellitus	0.004	0.996	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.004	0.996	0.000
G91.8 Other hydrocephalus	0.004	0.996	0.000
S00.7 Multiple superficial injuries of head	0.004	0.996	0.000
G91.1 Obstructive hydrocephalus	0.004	0.996	0.000
S00.4 Superficial injury of ear	0.004	0.996	0.000
F23 Acute and transient psychotic disorders	0.004	0.996	0.000
T23.2 Burn of second degree of wrist and hand	0.000	0.996	0.004
F20 Schizophrenia	0.004	0.996	0.000
C32.1 Supraglottis	0.004	0.996	0.000
Z97.8 Presence of other specified devices	0.000	0.996	0.004
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Z31.9 Procreative management, unspecified	0.004	0.996	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.004	0.996	0.000
O26.8 Other specified pregnancy-related conditions	0.000	0.996	0.004
G95.0 Syringomyelia and syringobulbia	0.004	0.996	0.000
E10.7 With multiple complications	0.004	0.996	0.000
Q54.0 Hypospadias, balanic	0.004	0.996	0.000
F22.8 Other persistent delusional disorders	0.002	0.996	0.002
D10.7 Hypopharynx	0.000	0.996	0.004
D10.2 Floor of mouth	0.000	0.996	0.004
D10.6 Nasopharynx	0.000	0.996	0.004
Z31.3 Other assisted fertilisation methods	0.004	0.996	0.000
E85.9 Amyloidosis, unspecified	0.004	0.996	0.000
D10.4 Tonsil	0.000	0.996	0.003
F22.9 Persistent delusional disorder, unspecified	0.002	0.996	0.001
O26.2 Pregnancy care of habitual aborter	0.000	0.996	0.004
G90-G99 Other disorders of the nervous system	0.004	0.996	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.996	0.000
T23 Burn and corrosion of wrist and hand	0.000	0.996	0.004
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.003	0.996	0.000
Q50.3 Other congenital malformations of ovary	0.003	0.996	0.000
Q50.2 Congenital torsion of ovary	0.003	0.996	0.000
Q50.1 Developmental ovarian cyst	0.003	0.996	0.000
Q50.0 Congenital absence of ovary	0.003	0.996	0.000
E10.6 With other specified complications	0.003	0.996	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.996	0.004
D37.4 Colon	0.004	0.996	0.000
G95.1 Vascular myelopathies	0.003	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
D10.5 Other parts of oropharynx	0.000	0.997	0.003
Z31.8 Other procreative management	0.003	0.997	0.000
D10.9 Pharynx, unspecified	0.000	0.997	0.003
E10.2 With renal complications	0.003	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.997	0.003
Z31.6 General counselling and advice on procreation	0.003	0.997	0.000
S00.1 Contusion of eyelid and periocular area	0.003	0.997	0.000
K70.0 Alcoholic fatty liver	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
Z31.5 Genetic counselling	0.003	0.997	0.000
Z31.1 Artifical insemination	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.003	0.997	0.000
K50.0 Crohn's disease of small intestine	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
E85.3 Secondary systemic amyloidosis	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.997	0.003
E10.1 With ketoacidosis	0.003	0.997	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.003	0.997	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M25.7 Osteophyte	0.000	0.997	0.003
K50 Crohn's disease [regional enteritis]	0.003	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.997	0.003
G95.8 Other specified diseases of spinal cord	0.003	0.997	0.000
F23.8 Other acute and transient psychotic disorders	0.003	0.997	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.003	0.997	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.003	0.997	0.000
F20.2 Catatonic schizophrenia	0.003	0.997	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.003	0.997	0.000
E85 Amyloidosis	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
T17.2 Foreign body in pharynx	0.000	0.997	0.003
F20.6 Simple schizophrenia	0.003	0.997	0.000
F20.4 Postschizophrenic depression	0.003	0.997	0.000
F20.3 Undifferentiated schizophrenia	0.003	0.997	0.000
F20.1 Hebephrenic schizophrenia	0.003	0.997	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.003	0.997	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.003	0.997	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
D33.3 Cranial nerves	0.003	0.997	0.000
Q51.3 Bicornate uterus	0.003	0.997	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.003	0.997	0.000
M25.51 Pain in joint (Shoulder region)	0.000	0.997	0.003
G94.2 Hydrocephalus in other diseases classified elsewhere	0.003	0.997	0.000
S01.5 Open wound of lip and oral cavity	0.003	0.997	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.997	0.003
F20.8 Other schizophrenia	0.003	0.997	0.000
O26.0 Excessive weight gain in pregnancy	0.000	0.997	0.003
I72.4 Aneurysm of artery of lower extremity	0.003	0.997	0.000
S72.1 Pertrochanteric fracture	0.003	0.997	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.003	0.997	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.997	0.003
Q52.1 Doubling of vagina	0.003	0.997	0.000
T23.1 Burn of first degree of wrist and hand	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.997	0.003
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
Q50.5 Embryonic cyst of broad ligament	0.003	0.997	0.000
R50.8 Other specified fever	0.000	0.997	0.003
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.997	0.003
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
S00.8 Superficial injury of other parts of head	0.003	0.997	0.000
E85.4 Organ-limited amyloidosis	0.003	0.997	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.997	0.000
Q52.3 Imperforate hymen	0.003	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.997	0.000
Q52.0 Congenital absence of vagina	0.003	0.997	0.000
G92 Toxic encephalopathy	0.003	0.997	0.000
E85.8 Other amyloidosis	0.003	0.997	0.000
G97.8 Other postprocedural disorders of nervous system	0.003	0.997	0.000
T23.7 Corrosion of third degree of wrist and hand	0.000	0.997	0.003
T23.6 Corrosion of second degree of wrist and hand	0.000	0.997	0.003
T23.5 Corrosion of first degree of wrist and hand	0.000	0.997	0.003
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.997	0.003
K72 Hepatic failure, not elsewhere classified	0.003	0.997	0.000
O26.4 Herpes gestationis	0.000	0.997	0.003
O26.1 Low weight gain in pregnancy	0.000	0.997	0.003
Q52.5 Fusion of labia	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.997	0.003
T23.3 Burn of third degree of wrist and hand	0.000	0.997	0.003
U89.8 Agent resistant to other single specified antibiotic	0.003	0.997	0.000
Z97.4 Presence of external hearing-aid	0.000	0.997	0.003
E11.5 With peripheral circulatory complications	0.000	0.997	0.003
G94.1 Hydrocephalus in neoplastic disease	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
M25.73 Osteophyte (Forearm)	0.000	0.997	0.003
Q51.4 Unicornate uterus	0.003	0.997	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.997	0.003
O26.5 Maternal hypotension syndrome	0.000	0.997	0.003
L27.0 Generalised skin eruption due to drugs and medicaments	0.003	0.997	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.002	0.997	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
E10.0 With coma	0.002	0.997	0.000
F20.5 Residual schizophrenia	0.002	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.997	0.000
Z03.3 Observation for suspected nervous system disorder	0.000	0.997	0.003
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.002	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.997	0.000
S01.8 Open wound of other parts of head	0.003	0.997	0.000
M25.70 Osteophyte (Multiple sites)	0.000	0.997	0.002
D86.0 Sarcoidosis of lung	0.000	0.997	0.003
E10.8 With unspecified complications	0.002	0.997	0.000
M25.78 Osteophyte (Other)	0.000	0.997	0.003
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.997	0.003
I44.3 Other and unspecified atrioventricular block	0.003	0.997	0.000
Z97 Presence of other devices	0.000	0.997	0.003
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.997	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.997	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.997	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.002
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.997	0.002
O23 Infections of genito-urinary tract in pregnancy	0.000	0.997	0.003
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.997	0.003
F20.9 Schizophrenia, unspecified	0.002	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.997	0.000
O20 Haemorrhage in early pregnancy	0.000	0.997	0.003
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.997	0.000
Q55.3 Atresia of vas deferens	0.002	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.997	0.000
Q55.0 Absence and aplasia of testis	0.002	0.997	0.000
Z97.3 Presence of spectacles and contact lenses	0.000	0.997	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
S72.11 Pertrochanteric fracture (open)	0.002	0.998	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.002	0.998	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.002	0.998	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.000	0.998	0.002
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
Q53 Undescended testicle	0.002	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.002	0.998	0.000
S00.3 Superficial injury of nose	0.002	0.998	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
I70 Atherosclerosis	0.000	0.998	0.002
O23.5 Infections of the genital tract in pregnancy	0.000	0.998	0.002
S00.5 Superficial injury of lip and oral cavity	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
W55.0 Home	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
O21 Excessive vomiting in pregnancy	0.000	0.998	0.002
G97.0 Cerebrospinal fluid leak from spinal puncture	0.002	0.998	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.998	0.002
I72 Other aneurysm	0.002	0.998	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.998	0.002
K50.8 Other Crohn's disease	0.002	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
Z97.0 Presence of artificial eye	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.000	0.998	0.002
I89.1 Lymphangitis	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
T25 Burn and corrosion of ankle and foot	0.000	0.998	0.002
O20.8 Other haemorrhage in early pregnancy	0.000	0.998	0.002
G99 Other disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
O22.1 Genital varices in pregnancy	0.000	0.998	0.002
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.998	0.002
O23.2 Infections of urethra in pregnancy	0.000	0.998	0.002
O23.1 Infections of bladder in pregnancy	0.000	0.998	0.002
O29 Complications of anaesthesia during pregnancy	0.000	0.998	0.002
O25 Malnutrition in pregnancy	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
I70.8 Atherosclerosis of other arteries	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.998	0.002
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.000	0.998	0.002
Q53.9 Undescended testicle, unspecified	0.002	0.998	0.000
Q53.0 Ectopic testis	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
A04.5 Campylobacter enteritis	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
G93.8 Other specified disorders of brain	0.002	0.998	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.998	0.002
O23.0 Infections of kidney in pregnancy	0.000	0.998	0.002
T21.2 Burn of second degree of trunk	0.000	0.998	0.002
I70.1 Atherosclerosis of renal artery	0.000	0.998	0.002
I72.1 Aneurysm of artery of upper extremity	0.002	0.998	0.000
K72.1 Chronic hepatic failure	0.002	0.998	0.000
T21.3 Burn of third degree of trunk	0.000	0.998	0.002
I72.9 Aneurysm of unspecified site	0.002	0.998	0.000
O22.9 Venous complication in pregnancy, unspecified	0.000	0.998	0.002
O22.8 Other venous complications in pregnancy	0.000	0.998	0.002
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.998	0.002
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.998	0.002
D33.0 Brain, supratentorial	0.002	0.998	0.000
H35.5 Hereditary retinal dystrophy	0.002	0.998	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.000	0.998	0.002
I72.6 Aneurysm and dissection of vertebral artery	0.002	0.998	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.002	0.998	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
Q53.2 Undescended testicle, bilateral	0.001	0.998	0.000
T21.7 Corrosion of third degree of trunk	0.000	0.998	0.002
T21.6 Corrosion of second degree of trunk	0.000	0.998	0.002
T21.5 Corrosion of first degree of trunk	0.000	0.998	0.002
T21.4 Corrosion of unspecified degree of trunk	0.000	0.998	0.002
T25.7 Corrosion of third degree of ankle and foot	0.000	0.998	0.002
T25.6 Corrosion of second degree of ankle and foot	0.000	0.998	0.002
T25.5 Corrosion of first degree of ankle and foot	0.000	0.998	0.002
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.998	0.002
T25.1 Burn of first degree of ankle and foot	0.000	0.998	0.002
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.998	0.002
Q21.0 Ventricular septal defect	0.000	0.998	0.002
T21.1 Burn of first degree of trunk	0.000	0.998	0.002
S01 Open wound of head	0.002	0.998	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.002	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.000	0.998	0.002
T25.3 Burn of third degree of ankle and foot	0.000	0.998	0.002
D33 Benign neoplasm of brain and other parts of central nervous system	0.002	0.998	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.998	0.002
M25.86 Other specified joint disorders (Lower leg)	0.000	0.998	0.002
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.998	0.002
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.998	0.002
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.6 Failed or difficult intubation during pregnancy	0.000	0.998	0.002
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.998	0.002
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.998	0.002
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.998	0.002
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.998	0.002
C56 Malignant neoplasm of ovary	0.000	0.998	0.002
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.998	0.002
M25.72 Osteophyte (Upper arm)	0.000	0.998	0.002
H61.2 Impacted cerumen	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.998	0.002
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.000	0.998	0.001
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.998	0.002
K00.6 Disturbances in tooth eruption	0.002	0.998	0.000
N99.0 Postprocedural renal failure	0.002	0.998	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.998	0.002
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.998	0.001
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.998	0.001
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.001
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.998	0.002
S06.6 Traumatic subarachnoid haemorrhage	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.998	0.002
T25.2 Burn of second degree of ankle and foot	0.000	0.998	0.001
H61.9 Disorder of external ear, unspecified	0.000	0.998	0.002
L23.5 Allergic contact dermatitis due to other chemical products	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.998	0.001
H35 Other retinal disorders	0.002	0.998	0.000
T17 Foreign body in respiratory tract	0.000	0.998	0.002
S37.00 Injury of kidney (without open wound into cavity)	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.002	0.998	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.000	0.998	0.002
T21.0 Burn of unspecified degree of trunk	0.000	0.998	0.001
U89 Agent resistant to other and unspecified antibiotics	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.002
Q53.1 Undescended testicle, unilateral	0.001	0.998	0.000
S01.9 Open wound of head, part unspecified	0.002	0.998	0.000
I44 Atrioventricular and left bundle-branch block	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.000	0.998	0.001
D33.9 Central nervous system, unspecified	0.001	0.998	0.000
D33.7 Other specified parts of central nervous system	0.001	0.998	0.000
D33.1 Brain, infratentorial	0.001	0.998	0.000
O21.2 Late vomiting of pregnancy	0.000	0.998	0.001
S01.2 Open wound of nose	0.002	0.998	0.000
T17.5 Foreign body in bronchus	0.000	0.998	0.001
L05.0 Pilonidal cyst with abscess	0.000	0.998	0.001
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.998	0.001
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.998	0.002
M25.74 Osteophyte (Hand)	0.000	0.998	0.001
D33.2 Brain, unspecified	0.001	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.001	0.998	0.000
T56.8 Other metals	0.001	0.998	0.000
A49.0 Staphylococcal infection, unspecified	0.002	0.998	0.000
I72.2 Aneurysm of renal artery	0.001	0.998	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.998	0.001
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.998	0.001
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations