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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12214416
log Bayes Factor = 11.1563
Chromosome 6   position 160,910,517  (GRCh37) Explore rs12214416 on Ensembl!
Variant rs12214416 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
I73 Other peripheral vascular diseases
0.000 0.002 0.998
I73.9 Peripheral vascular disease, unspecified
0.000 0.004 0.996
I25.2 Old myocardial infarction
0.000 0.005 0.995
I30-I52 Other forms of heart disease
0.000 0.007 0.993
I25.1 Atherosclerotic heart disease
0.000 0.008 0.992
I51 Complications and ill-defined descriptions of heart disease
0.000 0.012 0.988
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.019 0.981
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.019 0.981
I20.0 Unstable angina
0.000 0.020 0.980
I71 Aortic aneurysm and dissection
0.000 0.027 0.973
I51.7 Cardiomegaly
0.000 0.037 0.963
I50 Heart failure
0.000 0.041 0.959
I22 Subsequent myocardial infarction
0.000 0.048 0.952
I47 Paroxysmal tachycardia
0.000 0.060 0.940
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.064 0.936
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.089 0.911
I51.8 Other ill-defined heart diseases
0.000 0.093 0.907
I47.2 Ventricular tachycardia
0.000 0.112 0.888
I51.9 Heart disease, unspecified
0.000 0.118 0.882
I50.0 Congestive heart failure
0.000 0.121 0.879
I25.5 Ischaemic cardiomyopathy
0.000 0.122 0.878
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.127 0.873
I74 Arterial embolism and thrombosis
0.000 0.130 0.870
I73.0 Raynaud's syndrome
0.000 0.130 0.870
I77 Other disorders of arteries and arterioles
0.000 0.164 0.836
I50.1 Left ventricular failure
0.000 0.176 0.824
I30 Acute pericarditis
0.000 0.177 0.823
I05-I09 Chronic rheumatic heart diseases
0.000 0.189 0.811
I31 Other diseases of pericardium
0.000 0.190 0.810
I46 Cardiac arrest
0.000 0.193 0.807
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.201 0.799
I47.1 Supraventricular tachycardia
0.000 0.205 0.795
I50.9 Heart failure, unspecified
0.000 0.206 0.794
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.221 0.779
I24 Other acute ischaemic heart diseases
0.000 0.233 0.766
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.251 0.749
I36 Nonrheumatic tricuspid valve disorders
0.000 0.260 0.740
I70 Atherosclerosis
0.000 0.263 0.737
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.271 0.729
I71.0 Dissection of aorta [any part]
0.000 0.274 0.726
I37 Pulmonary valve disorders
0.000 0.275 0.725
I31.9 Disease of pericardium, unspecified
0.000 0.276 0.724
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.280 0.720
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.4 Coronary artery aneurysm
0.000 0.283 0.717
I25.3 Aneurysm of heart
0.000 0.283 0.717
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.283 0.717
I08 Multiple valve diseases
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
I73.8 Other specified peripheral vascular diseases
0.000 0.284 0.716
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.284 0.716
I52 Other heart disorders in diseases classified elsewhere
0.000 0.288 0.712
I48 Atrial fibrillation and flutter
0.000 0.288 0.712
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.288 0.712
I41 Myocarditis in diseases classified elsewhere
0.000 0.288 0.712
I40 Acute myocarditis
0.000 0.288 0.712
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.288 0.712
I32 Pericarditis in diseases classified elsewhere
0.000 0.288 0.712
I51.5 Myocardial degeneration
0.000 0.291 0.709
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.291 0.709
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.291 0.709
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.291 0.709
I51.0 Cardiac septal defect, acquired
0.000 0.291 0.709
I77.6 Arteritis, unspecified
0.000 0.297 0.703
I30.9 Acute pericarditis, unspecified
0.000 0.298 0.702
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.302 0.698
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.302 0.698
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.302 0.698
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.302 0.698
I77.1 Stricture of artery
0.000 0.302 0.698
I27 Other pulmonary heart diseases
0.000 0.308 0.692
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.323 0.677
I51.4 Myocarditis, unspecified
0.000 0.324 0.676
I47.0 Reentry ventricular arrhythmia
0.000 0.326 0.674
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.326 0.674
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.328 0.672
I74.5 Embolism and thrombosis of iliac artery
0.000 0.335 0.665
I51.6 Cardiovascular disease, unspecified
0.000 0.341 0.659
I46.0 Cardiac arrest with successful resuscitation
0.000 0.342 0.658
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.355 0.645
I20.1 Angina pectoris with documented spasm
0.000 0.368 0.632
I80 Phlebitis and thrombophlebitis
0.000 0.368 0.632
I07 Rheumatic tricuspid valve diseases
0.000 0.370 0.630
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.370 0.629
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.376 0.624
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.376 0.624
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.376 0.624
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.376 0.624
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.376 0.624
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.385 0.615
I22.8 Subsequent myocardial infarction of other sites
0.000 0.394 0.606
I46.9 Cardiac arrest, unspecified
0.000 0.400 0.600
I77.5 Necrosis of artery
0.000 0.400 0.599
I77.4 Coeliac artery compression syndrome
0.000 0.400 0.599
I77.3 Arterial fibromuscular dysplasia
0.000 0.400 0.599
I77.2 Rupture of artery
0.000 0.400 0.599
I77.0 Arteriovenous fistula, acquired
0.000 0.400 0.599
I30.8 Other forms of acute pericarditis
0.000 0.410 0.590
I30.1 Infective pericarditis
0.000 0.410 0.590
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.410 0.590
I27.0 Primary pulmonary hypertension
0.000 0.412 0.588
I72 Other aneurysm
0.000 0.416 0.584
I09 Other rheumatic heart diseases
0.000 0.418 0.581
I06 Rheumatic aortic valve diseases
0.000 0.418 0.581
I31.8 Other specified diseases of pericardium
0.000 0.419 0.581
I31.2 Haemopericardium, not elsewhere classified
0.000 0.419 0.581
I31.1 Chronic constrictive pericarditis
0.000 0.419 0.581
I31.0 Chronic adhesive pericarditis
0.000 0.419 0.581
I46.1 Sudden cardiac death, so described
0.000 0.422 0.578
I33 Acute and subacute endocarditis
0.000 0.425 0.575
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.426 0.574
I28 Other diseases of pulmonary vessels
0.000 0.427 0.573
I74.8 Embolism and thrombosis of other arteries
0.000 0.430 0.569
I77.8 Other specified disorders of arteries and arterioles
0.000 0.436 0.564
I45 Other conduction disorders
0.000 0.438 0.562
I42 Cardiomyopathy
0.000 0.440 0.560
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.441 0.558
I86 Varicose veins of other sites
0.000 0.442 0.557
I21 Acute myocardial infarction
0.000 0.449 0.551
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.449 0.551
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.450 0.550
I27.2 Other secondary pulmonary hypertension
0.000 0.452 0.548
I70.0 Atherosclerosis of aorta
0.000 0.453 0.547
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.465 0.535
I81 Portal vein thrombosis
0.000 0.466 0.534
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.467 0.533
I37.1 Pulmonary valve insufficiency
0.000 0.467 0.533
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.469 0.531
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.469 0.531
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.469 0.531
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.469 0.531
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.469 0.531
I70.9 Generalised and unspecified atherosclerosis
0.000 0.471 0.529
I70.8 Atherosclerosis of other arteries
0.000 0.471 0.529
I70.1 Atherosclerosis of renal artery
0.000 0.471 0.529
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.475 0.525
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.475 0.525
I38 Endocarditis, valve unspecified
0.000 0.475 0.525
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.477 0.523
I79.1 Aortitis in diseases classified elsewhere
0.000 0.477 0.523
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.477 0.523
I37.9 Pulmonary valve disorder, unspecified
0.000 0.480 0.520
I37.8 Other pulmonary valve disorders
0.000 0.480 0.520
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.480 0.520
I37.0 Pulmonary valve stenosis
0.000 0.480 0.520
I08.8 Other multiple valve diseases
0.000 0.485 0.514
I08.9 Multiple valve disease, unspecified
0.000 0.486 0.514
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I02 Rheumatic chorea
0.000 0.486 0.514
I01 Rheumatic fever with heart involvement
0.000 0.486 0.514
I00 Rheumatic fever without mention of heart involvement
0.000 0.486 0.514
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.489 0.511
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.489 0.511
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.489 0.511
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.489 0.511
I40.9 Acute myocarditis, unspecified
0.000 0.489 0.511
I40.8 Other acute myocarditis
0.000 0.489 0.511
I40.1 Isolated myocarditis
0.000 0.489 0.511
I40.0 Infective myocarditis
0.000 0.489 0.511
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.489 0.511
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.489 0.511
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.489 0.511
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.489 0.511
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.489 0.511
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.489 0.511
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.489 0.511
I48.4 Atypical atrial flutter
0.000 0.489 0.511
I48.3 Typical atrial flutter
0.000 0.489 0.511
I48.2 Chronic atrial fibrillation
0.000 0.489 0.511
I48.1 Persistent atrial fibrillation
0.000 0.489 0.511
I48.0 Paroxysmal atrial fibrillation
0.000 0.489 0.511
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.489 0.511
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.489 0.511
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.489 0.511
I08.0 Disorders of both mitral and aortic valves
0.000 0.492 0.508
I34 Nonrheumatic mitral valve disorders
0.000 0.494 0.506
I07.1 Tricuspid insufficiency
0.000 0.500 0.500
I85 Oesophageal varices
0.000 0.503 0.497
I27.9 Pulmonary heart disease, unspecified
0.000 0.504 0.496
I27.8 Other specified pulmonary heart diseases
0.000 0.504 0.496
I27.1 Kyphoscoliotic heart disease
0.000 0.504 0.496
I26 Pulmonary embolism
0.000 0.506 0.494
I86.1 Scrotal varices
0.000 0.510 0.490
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.512 0.488
I88 Nonspecific lymphadenitis
0.000 0.518 0.482
I78 Diseases of capillaries
0.001 0.526 0.474
I45.9 Conduction disorder, unspecified
0.000 0.534 0.466
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.535 0.465
I31.3 Pericardial effusion (noninflammatory)
0.000 0.539 0.461
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.540 0.460
I24.1 Dressler's syndrome
0.000 0.542 0.457
I07.9 Tricuspid valve disease, unspecified
0.000 0.548 0.452
I07.8 Other tricuspid valve diseases
0.000 0.548 0.452
I07.2 Tricuspid stenosis with insufficiency
0.000 0.548 0.452
I07.0 Tricuspid stenosis
0.000 0.548 0.452
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.554 0.446
I21.4 Acute subendocardial myocardial infarction
0.000 0.557 0.443
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.557 0.443
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.557 0.442
I42.9 Cardiomyopathy, unspecified
0.000 0.558 0.442
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.560 0.440
I10-I15 Hypertensive diseases
0.000 0.560 0.440
I20.8 Other forms of angina pectoris
0.000 0.565 0.435
I72.8 Aneurysm of other specified arteries
0.000 0.572 0.428
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.581 0.419
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.581 0.419
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.581 0.419
I72.2 Aneurysm of renal artery
0.000 0.581 0.419
I72.1 Aneurysm of artery of upper extremity
0.000 0.581 0.419
I72.3 Aneurysm of iliac artery
0.000 0.582 0.418
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.583 0.417
I06.8 Other rheumatic aortic valve diseases
0.000 0.583 0.417
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.583 0.417
I06.1 Rheumatic aortic insufficiency
0.000 0.583 0.417
I06.0 Rheumatic aortic stenosis
0.000 0.583 0.417
I09.9 Rheumatic heart disease, unspecified
0.000 0.583 0.417
I09.8 Other specified rheumatic heart diseases
0.000 0.583 0.417
I09.2 Chronic rheumatic pericarditis
0.000 0.583 0.417
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.583 0.417
I09.0 Rheumatic myocarditis
0.000 0.583 0.417
I33.9 Acute endocarditis, unspecified
0.000 0.588 0.412
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.589 0.411
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.589 0.411
I28.8 Other specified diseases of pulmonary vessels
0.000 0.589 0.411
I28.1 Aneurysm of pulmonary artery
0.000 0.589 0.411
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.589 0.411
I45.2 Bifascicular block
0.000 0.590 0.410
I82 Other venous embolism and thrombosis
0.000 0.591 0.409
I42.2 Other hypertrophic cardiomyopathy
0.000 0.594 0.406
I45.4 Nonspecific intraventricular block
0.000 0.597 0.403
I45.3 Trifascicular block
0.000 0.597 0.403
I45.0 Right fascicular block
0.000 0.597 0.403
I42.8 Other cardiomyopathies
0.000 0.598 0.402
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.598 0.401
I42.5 Other restrictive cardiomyopathy
0.000 0.598 0.401
I42.4 Endocardial fibroelastosis
0.000 0.598 0.401
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.598 0.401
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.599 0.401
I86.4 Gastric varices
0.000 0.600 0.400
I86.3 Vulval varices
0.000 0.600 0.400
I86.2 Pelvic varices
0.000 0.600 0.400
I86.0 Sublingual varices
0.000 0.600 0.400
I72.4 Aneurysm of artery of lower extremity
0.000 0.604 0.396
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.605 0.395
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.605 0.395
I99 Other and unspecified disorders of circulatory system
0.000 0.607 0.393
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.607 0.392
I05 Rheumatic mitral valve diseases
0.001 0.608 0.391
I45.6 Preexcitation syndrome
0.000 0.615 0.384
I72.0 Aneurysm of carotid artery
0.000 0.615 0.384
I87 Other disorders of veins
0.000 0.616 0.384
I45.8 Other specified conduction disorders
0.000 0.616 0.384
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.617 0.382
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.619 0.380
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.621 0.379
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.621 0.379
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.621 0.379
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.621 0.379
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.621 0.379
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.621 0.379
I83 Varicose veins of lower extremities
0.000 0.622 0.378
I85.9 Oesophageal varices without bleeding
0.000 0.624 0.375
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.631 0.369
I01.8 Other acute rheumatic heart disease
0.000 0.631 0.369
I01.2 Acute rheumatic myocarditis
0.000 0.631 0.369
I01.1 Acute rheumatic endocarditis
0.000 0.631 0.369
I01.0 Acute rheumatic pericarditis
0.000 0.631 0.369
I02.9 Rheumatic chorea without heart involvement
0.000 0.631 0.369
I02.0 Rheumatic chorea with heart involvement
0.000 0.631 0.369
I86.8 Varicose veins of other specified sites
0.000 0.634 0.366
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.637 0.363
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.637 0.363
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.637 0.363
I72.9 Aneurysm of unspecified site
0.000 0.642 0.357
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.645 0.355
I85.0 Oesophageal varices with bleeding
0.000 0.647 0.353
I21.9 Acute myocardial infarction, unspecified
0.000 0.648 0.352
I44 Atrioventricular and left bundle-branch block
0.000 0.653 0.347
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.654 0.345
I88.8 Other nonspecific lymphadenitis
0.000 0.654 0.345
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.654 0.345
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.654 0.345
I78.9 Disease of capillaries, unspecified
0.001 0.660 0.340
I78.8 Other diseases of capillaries
0.001 0.660 0.340
I11 Hypertensive heart disease
0.000 0.666 0.334
I42.6 Alcoholic cardiomyopathy
0.000 0.672 0.328
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.674 0.325
Z95.1 Presence of aortocoronary bypass graft
0.000 0.677 0.323
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.680 0.319
I13 Hypertensive heart and renal disease
0.000 0.684 0.316
I24.8 Other forms of acute ischaemic heart disease
0.000 0.685 0.314
I34.1 Mitral (valve) prolapse
0.000 0.687 0.313
I45.5 Other specified heart block
0.000 0.687 0.313
I78.0 Hereditary haemorrhagic telangiectasia
0.001 0.691 0.308
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.693 0.306
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.699 0.301
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.699 0.301
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.699 0.301
I98.0 Cardiovascular syphilis
0.000 0.699 0.301
I35 Nonrheumatic aortic valve disorders
0.000 0.704 0.296
I82.3 Embolism and thrombosis of renal vein
0.000 0.707 0.293
I82.1 Thrombophlebitis migrans
0.000 0.707 0.293
I82.0 Budd-Chiari syndrome
0.000 0.707 0.293
I95 Hypotension
0.000 0.707 0.293
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.710 0.290
I45.1 Other and unspecified right bundle-branch block
0.000 0.710 0.290
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.712 0.288
I60-I69 Cerebrovascular diseases
0.000 0.712 0.288
I15 Secondary hypertension
0.000 0.718 0.281
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.719 0.281
I05.8 Other mitral valve diseases
0.001 0.719 0.280
I05.1 Rheumatic mitral insufficiency
0.001 0.719 0.280
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.720 0.279
I82.2 Embolism and thrombosis of vena cava
0.000 0.722 0.278
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.724 0.276
I87.9 Disorder of vein, unspecified
0.000 0.725 0.275
I87.0 Postphlebitic syndrome
0.000 0.725 0.275
I33.0 Acute and subacute infective endocarditis
0.001 0.725 0.274
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.726 0.274
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.729 0.271
I44.1 Atrioventricular block, second degree
0.000 0.733 0.267
I82.8 Embolism and thrombosis of other specified veins
0.000 0.733 0.267
I87.1 Compression of vein
0.000 0.741 0.258
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.742 0.258
I89.1 Lymphangitis
0.000 0.742 0.257
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.744 0.255
I44.5 Left posterior fascicular block
0.000 0.751 0.249
I44.4 Left anterior fascicular block
0.000 0.751 0.249
I34.0 Mitral (valve) insufficiency
0.000 0.754 0.246
I62 Other nontraumatic intracranial haemorrhage
0.000 0.755 0.245
I89.0 Lymphoedema, not elsewhere classified
0.000 0.756 0.244
I05.9 Mitral valve disease, unspecified
0.001 0.759 0.241
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.760 0.240
I05.0 Mitral stenosis
0.001 0.763 0.236
I44.3 Other and unspecified atrioventricular block
0.000 0.766 0.234
I05.2 Mitral stenosis with insufficiency
0.001 0.767 0.232
I10 Essential (primary) hypertension
0.000 0.769 0.231
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.771 0.229
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.771 0.229
I97.0 Postcardiotomy syndrome
0.000 0.771 0.229
I95.1 Orthostatic hypotension
0.000 0.771 0.229
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.773 0.226
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.773 0.226
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.773 0.226
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.773 0.226
I44.6 Other and unspecified fascicular block
0.000 0.776 0.224
I12 Hypertensive renal disease
0.000 0.779 0.220
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.780 0.220
I44.2 Atrioventricular block, complete
0.000 0.782 0.217
I63 Cerebral infarction
0.000 0.783 0.217
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.784 0.216
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.788 0.211
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.788 0.212
I95.0 Idiopathic hypotension
0.000 0.789 0.210
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.790 0.210
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.793 0.206
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.793 0.206
I35.8 Other aortic valve disorders
0.000 0.795 0.205
I95.9 Hypotension, unspecified
0.000 0.798 0.202
I15.9 Seconday hypertension, unspecified
0.000 0.798 0.202
I15.8 Other secondary hypertension
0.000 0.798 0.202
I15.2 Hypertension secondary to endocrine disorders
0.000 0.798 0.202
I15.0 Renovascular hypertension
0.000 0.798 0.202
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.798 0.202
I35.9 Aortic valve disorder, unspecified
0.000 0.800 0.200
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.800 0.200
I87.8 Other specified disorders of veins
0.001 0.802 0.198
I44.0 Atrioventricular block, first degree
0.000 0.809 0.191
I35.1 Aortic (valve) insufficiency
0.000 0.810 0.190
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.818 0.182
I97.1 Other functional disturbances following cardiac surgery
0.001 0.819 0.181
I95.8 Other hypotension
0.000 0.820 0.180
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.820 0.180
I63.9 Cerebral infarction, unspecified
0.000 0.821 0.179
I62.1 Nontraumatic extradural haemorrhage
0.000 0.824 0.175
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.826 0.173
I67 Other cerebrovascular diseases
0.000 0.829 0.171
I78.1 Naevus, nonneoplastic
0.001 0.831 0.168
I15.1 Hypertension secondary to other renal disorders
0.000 0.832 0.167
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.834 0.166
Z95.0 Presence of cardiac pacemaker
0.000 0.834 0.166
I65.2 Occlusion and stenosis of carotid artery
0.000 0.836 0.164
I44.7 Left bundle-branch block, unspecified
0.000 0.837 0.163
I42.0 Dilated cardiomyopathy
0.001 0.839 0.160
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.844 0.155
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.844 0.155
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.844 0.155
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.844 0.155
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.845 0.155
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.845 0.155
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.845 0.155
I65.1 Occlusion and stenosis of basilar artery
0.000 0.845 0.155
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.845 0.155
Z95.3 Presence of xenogenic heart valve
0.000 0.847 0.153
I63.8 Other cerebral infarction
0.000 0.848 0.152
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.852 0.148
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.852 0.148
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.852 0.148
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.852 0.148
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.852 0.148
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.852 0.148
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.852 0.148
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.852 0.148
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.852 0.148
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.852 0.148
I68.0 Cerebral amyloid angiopathy
0.000 0.852 0.148
I12.9 Hypertensive renal disease without renal failure
0.000 0.854 0.145
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.856 0.144
I95.2 Hypotension due to drugs
0.000 0.865 0.135
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.866 0.134
I67.9 Cerebrovascular disease, unspecified
0.000 0.868 0.132
I49 Other cardiac arrhythmias
0.001 0.870 0.129
Z95.4 Presence of other heart-valve replacement
0.000 0.874 0.126
I67.8 Other specified cerebrovascular diseases
0.000 0.875 0.125
I60 Subarachnoid haemorrhage
0.000 0.877 0.123
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.877 0.123
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.877 0.123
I67.5 Moyamoya disease
0.000 0.877 0.123
I67.4 Hypertensive encephalopathy
0.000 0.877 0.123
I67.3 Progressive vascular leukoencephalopathy
0.000 0.877 0.123
I67.1 Cerebral aneurysm, nonruptured
0.000 0.881 0.119
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.890 0.110
I61 Intracerebral haemorrhage
0.001 0.890 0.110
I69 Sequelae of cerebrovascular disease
0.000 0.894 0.106
I49.8 Other specified cardiac arrhythmias
0.000 0.898 0.101
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.001 0.898 0.101
I35.0 Aortic (valve) stenosis
0.000 0.906 0.094
I67.2 Cerebral atherosclerosis
0.000 0.906 0.094
I49.2 Junctional premature depolarisation
0.001 0.907 0.092
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.908 0.092
I12.0 Hypertensive renal disease with renal failure
0.000 0.910 0.089
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.911 0.088
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.911 0.088
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.911 0.088
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.911 0.088
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.911 0.088
I49.0 Ventricular fibrillation and flutter
0.001 0.914 0.086
I60.8 Other subarachnoid haemorrhage
0.000 0.917 0.083
I61.8 Other intracerebral haemorrhage
0.001 0.921 0.079
I61.6 Intracerebral haemorrhage, multiple localised
0.001 0.921 0.079
I61.4 Intracerebral haemorrhage in cerebellum
0.001 0.921 0.079
I61.3 Intracerebral haemorrhage in brain stem
0.001 0.921 0.079
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.001 0.921 0.079
I49.4 Other and unspecified premature depolarisation
0.001 0.922 0.077
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.922 0.077
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.924 0.076
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.925 0.075
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.926 0.074
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.928 0.072
I49.1 Atrial premature depolarisation
0.001 0.928 0.071
I84 Haemorrhoids
0.000 0.929 0.071
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.001 0.929 0.070
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.930 0.070
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.933 0.067
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.937 0.063
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.001 0.937 0.062
I69.3 Sequelae of cerebral infarction
0.000 0.938 0.062
I61.5 Intracerebral haemorrhage, intraventricular
0.001 0.940 0.060
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.940 0.060
I84.2 Internal haemorrhoids without complication
0.000 0.940 0.059
I49.5 Sick sinus syndrome
0.001 0.943 0.056
I49.9 Cardiac arrhythmia, unspecified
0.001 0.945 0.054
I49.3 Ventricular premature depolarisation
0.001 0.946 0.053
I84.3 External thrombosed haemorrhoids
0.000 0.947 0.053
M13.9 Arthritis, unspecified
0.000 0.949 0.051
I69.1 Sequelae of intracerebral haemorrhage
0.001 0.951 0.048
I84.6 Residual haemorrhoidal skin tags
0.000 0.951 0.049
I84.4 External haemorrhoids with other complications
0.000 0.952 0.048
I84.0 Internal thrombosed haemorrhoids
0.000 0.953 0.047
M13.94 Arthritis, unspecified (Hand)
0.000 0.955 0.045
I84.5 External haemorrhoids without complication
0.000 0.955 0.045
I84.7 Unspecified thrombosed haemorrhoids
0.000 0.956 0.044
D05.1 Intraductal carcinoma in situ
0.000 0.957 0.043
M13.91 Arthritis, unspecified (Shoulder region)
0.000 0.957 0.043
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.958 0.042
I84.9 Unspecified haemorrhoids without complication
0.000 0.959 0.041
M13.93 Arthritis, unspecified (Forearm)
0.000 0.959 0.041
M13.98 Arthritis, unspecified (Other)
0.000 0.961 0.038
M13.97 Arthritis, unspecified (Ankle and foot)
0.000 0.962 0.038

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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