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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12308914
log Bayes Factor = 12.8877
Chromosome 12   position 104,633,842  (GRCh37) Explore rs12308914 on Ensembl!
Variant rs12308914 is part of Cluster X0111

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.999 0.001 0.000
G40-G47 Episodic and paroxysmal disorders
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
G62 Other polyneuropathies
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.991 0.009 0.000
I69 Sequelae of cerebrovascular disease
0.989 0.011 0.000
I60-I69 Cerebrovascular diseases
0.989 0.011 0.000
G62.9 Polyneuropathy, unspecified
0.988 0.012 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.987 0.013 0.000
G47 Sleep disorders
0.986 0.014 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.982 0.018 0.000
O60-O75 Complications of labour and delivery
0.979 0.021 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.977 0.023 0.000
Chapter XXI Factors influencing health status and contact with health services
0.970 0.030 0.000
Chapter I Certain infectious and parasitic diseases
0.968 0.032 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.967 0.033 0.000
G47.3 Sleep apnoea
0.966 0.034 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.963 0.037 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.961 0.039 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.960 0.040 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.956 0.044 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.954 0.046 0.000
Chapter X Diseases of the respiratory system
0.954 0.046 0.000
Z30 Contraceptive management
0.951 0.049 0.000
E10-E14 Diabetes mellitus
0.950 0.050 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.949 0.051 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.946 0.054 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.946 0.054 0.000
G20-G26 Extrapyramidal and movement disorders
0.944 0.056 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.939 0.061 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.938 0.062 0.000
Z35 Supervision of high-risk pregnancy
0.936 0.064 0.000
G81 Hemiplegia
0.935 0.065 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.933 0.067 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.932 0.068 0.000
J95-J99 Other diseases of the respiratory system
0.930 0.070 0.000
D70 Agranulocytosis
0.926 0.074 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.924 0.076 0.000
G44 Other headache syndromes
0.918 0.082 0.000
J40-J47 Chronic lower respiratory diseases
0.917 0.083 0.000
S70-S79 Injuries to the hip and thigh
0.916 0.084 0.000
E10 Insulin-dependent diabetes mellitus
0.913 0.087 0.000
I69.3 Sequelae of cerebral infarction
0.905 0.095 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.905 0.095 0.000
J98 Other respiratory disorders
0.905 0.095 0.000
G81.9 Hemiplegia, unspecified
0.904 0.096 0.000
G20 Parkinson's disease
0.901 0.099 0.000
G70-G73 Diseases of myoneural junction and muscle
0.894 0.106 0.000
A30-A49 Other bacterial diseases
0.893 0.107 0.000
G61 Inflammatory polyneuropathy
0.891 0.109 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.889 0.111 0.000
S60-S69 Injuries to the wrist and hand
0.884 0.116 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.884 0.116 0.000
M05-M14 Inflammatory polyarthropathies
0.882 0.118 0.000
G41 Status epilepticus
0.881 0.119 0.000
J44 Other chronic obstructive pulmonary disease
0.880 0.120 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.879 0.121 0.000
Z53.9 Procedure not carried out, unspecified reason
0.878 0.122 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.878 0.122 0.000
O61 Failed induction of labour
0.877 0.123 0.000
I71 Aortic aneurysm and dissection
0.877 0.123 0.000
G43 Migraine
0.876 0.124 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.875 0.125 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.873 0.127 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.871 0.129 0.000
G44.2 Tension-type headache
0.866 0.134 0.000
Y52 Agents primarily affecting the cardiovascular system
0.865 0.135 0.000
O20 Haemorrhage in early pregnancy
0.865 0.135 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.864 0.136 0.000
J98.1 Pulmonary collapse
0.860 0.140 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.859 0.141 0.000
Y86 Sequelae of other accidents
0.859 0.141 0.000
O72 Postpartum haemorrhage
0.854 0.146 0.000
I05-I09 Chronic rheumatic heart diseases
0.851 0.149 0.000
E11 Non-insulin-dependent diabetes mellitus
0.850 0.150 0.000
M06 Other rheumatoid arthritis
0.850 0.150 0.000
O62 Abnormalities of forces of labour
0.846 0.154 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.845 0.155 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.845 0.155 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.842 0.158 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.841 0.159 0.000
W20-W49 Exposure to inanimate mechanical forces
0.838 0.162 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.835 0.165 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.833 0.167 0.000
S70 Superficial injury of hip and thigh
0.831 0.169 0.000
O66 Other obstructed labour
0.831 0.169 0.000
Y40 Systemic antibiotics
0.830 0.169 0.000
J47 Bronchiectasis
0.825 0.175 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.824 0.176 0.000
W00-W19 Falls
0.822 0.178 0.000
I74 Arterial embolism and thrombosis
0.822 0.178 0.000
G30-G32 Other degenerative diseases of the nervous system
0.820 0.180 0.000
E14 Unspecified diabetes mellitus
0.819 0.181 0.000
E00-E07 Disorders of thyroid gland
0.815 0.185 0.000
M86-M90 Other osteopathies
0.814 0.186 0.000
I73 Other peripheral vascular diseases
0.813 0.187 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.812 0.188 0.000
O75.0 Maternal distress during labour and delivery
0.812 0.188 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.811 0.189 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.811 0.189 0.000
G63.2 Diabetic polyneuropathy
0.811 0.189 0.000
E10.4 With neurological complications
0.807 0.193 0.000
Z39 Postpartum care and examination
0.805 0.195 0.000
G72 Other myopathies
0.804 0.196 0.000
Y42.5 Other oestrogens and progestogens
0.804 0.196 0.000
O61.0 Failed medical induction of labour
0.804 0.196 0.000
E10.1 With ketoacidosis
0.801 0.199 0.000
A49 Bacterial infection of unspecified site
0.800 0.200 0.000
M06.9 Rheumatoid arthritis, unspecified
0.799 0.201 0.000
J46 Status asthmaticus
0.795 0.205 0.000
Chapter VIII Diseases of the ear and mastoid process
0.795 0.205 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.794 0.206 0.000
S80-S89 Injuries to the knee and lower leg
0.790 0.210 0.000
E10.3 With ophthalmic complications
0.790 0.210 0.000
O42 Premature rupture of membranes
0.788 0.212 0.000
S61 Open wound of wrist and hand
0.787 0.213 0.000
B25-B34 Other viral diseases
0.786 0.214 0.000
E13 Other specified diabetes mellitus
0.786 0.214 0.000
G62.8 Other specified polyneuropathies
0.785 0.214 0.000
O44 Placenta praevia
0.785 0.215 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.783 0.217 0.000
Z30.3 Menstrual extraction
0.782 0.218 0.000
M80-M85 Disorders of bone density and structure
0.781 0.219 0.000
Z42 Follow-up care involving plastic surgery
0.781 0.219 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.780 0.220 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.779 0.221 0.000
G81.1 Spastic hemiplegia
0.778 0.222 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.778 0.222 0.000
O72.1 Other immediate postpartum haemorrhage
0.778 0.222 0.000
I70 Atherosclerosis
0.777 0.223 0.000
S72 Fracture of femur
0.777 0.223 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.776 0.224 0.000
A00-A09 Intestinal infectious diseases
0.775 0.225 0.000
G61.0 Guillain-Barre syndrome
0.775 0.225 0.000
S62 Fracture at wrist and hand level
0.775 0.225 0.000
S50-S59 Injuries to the elbow and forearm
0.774 0.226 0.000
O85-O92 Complications predominantly related to the puerperium
0.774 0.226 0.000
O21 Excessive vomiting in pregnancy
0.774 0.226 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.773 0.227 0.000
S10-S19 Injuries to the neck
0.770 0.229 0.000
A40 Streptococcal septicaemia
0.770 0.230 0.000
O45 Premature separation of placenta [abruptio placentae]
0.769 0.231 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.768 0.232 0.000
D72 Other disorders of white blood cells
0.765 0.235 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.762 0.238 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.762 0.238 0.000
O75.8 Other specified complications of labour and delivery
0.762 0.238 0.000
E11.0 With coma
0.762 0.238 0.000
Z35.5 Supervision of elderly primigravida
0.762 0.238 0.000
W13 Fall from, out of or through building or structure
0.761 0.239 0.000
G47.9 Sleep disorder, unspecified
0.759 0.241 0.000
T79-T79 Certain early complications of trauma
0.758 0.242 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.755 0.244 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.755 0.245 0.000
G82 Paraplegia and tetraplegia
0.754 0.246 0.000
G47.4 Narcolepsy and cataplexy
0.753 0.247 0.000
G41.9 Status epilepticus, unspecified
0.752 0.248 0.000
S70.1 Contusion of thigh
0.752 0.248 0.000
V80-V89 Other land transport accidents
0.750 0.250 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.750 0.250 0.000
T66-T78 Other and unspecified effects of external causes
0.750 0.250 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.749 0.251 0.000
B50-B64 Protozoal diseases
0.748 0.252 0.000
O80-O84 Delivery
0.748 0.252 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.747 0.253 0.000
H60-H62 Diseases of external ear
0.747 0.253 0.000
I61 Intracerebral haemorrhage
0.746 0.254 0.000
G43.9 Migraine, unspecified
0.746 0.254 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.745 0.255 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.743 0.257 0.000
D73 Diseases of spleen
0.742 0.258 0.000
S61.8 Open wound of other parts of wrist and hand
0.742 0.258 0.000
I08 Multiple valve diseases
0.742 0.258 0.000
T00-T07 Injuries involving multiple body regions
0.742 0.258 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.742 0.258 0.000
Y88 Sequelae of surgical and medical care as external cause
0.741 0.259 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
B99-B99 Other infectious diseases
0.741 0.259 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.741 0.259 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.741 0.259 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.741 0.259 0.000
I60 Subarachnoid haemorrhage
0.740 0.260 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.739 0.261 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.739 0.261 0.000
E11.4 With neurological complications
0.738 0.262 0.000
G25 Other extrapyramidal and movement disorders
0.738 0.262 0.000
M06.4 Inflammatory polyarthropathy
0.737 0.263 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.736 0.264 0.000
Y40.0 Penicillins
0.736 0.264 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.735 0.264 0.000
Y43 Primarily systemic agents
0.735 0.265 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.735 0.265 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.732 0.268 0.000
O41 Other disorders of amniotic fluid and membranes
0.728 0.272 0.000
O40 Polyhydramnios
0.728 0.272 0.000
G43.1 Migraine with aura [classical migraine]
0.728 0.272 0.000
X50-X57 Overexertion, travel and privation
0.728 0.272 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.728 0.272 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.727 0.273 0.000
G60 Hereditary and idiopathic neuropathy
0.726 0.274 0.000
A46 Erysipelas
0.726 0.274 0.000
E11.1 With ketoacidosis
0.726 0.274 0.000
S80 Superficial injury of lower leg
0.725 0.275 0.000
J98.6 Disorders of diaphragm
0.725 0.275 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.725 0.275 0.000
M13 Other arthritis
0.725 0.275 0.000
M11 Other crystal arthropathies
0.724 0.276 0.000
B35-B49 Mycoses
0.724 0.276 0.000
X10-X19 Contact with heat and hot substances
0.723 0.277 0.000
O30 Multiple gestation
0.722 0.278 0.000
G47.8 Other sleep disorders
0.722 0.278 0.000
O69.8 Labour and delivery complicated by other cord complications
0.721 0.279 0.000
Y48 Anaesthetics and therapeutic gases
0.721 0.279 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.721 0.279 0.000
G61.8 Other inflammatory polyneuropathies
0.721 0.279 0.000
O20.0 Threatened abortion
0.720 0.280 0.000
Y89 Sequelae of other external causes
0.719 0.281 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.719 0.281 0.000
G41.0 Grand mal status epilepticus
0.719 0.281 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
H61 Other disorders of external ear
0.718 0.282 0.000
I62 Other nontraumatic intracranial haemorrhage
0.717 0.283 0.000
O62.2 Other uterine inertia
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
W13.9 Unspecified place
0.717 0.283 0.000
I71.0 Dissection of aorta [any part]
0.716 0.284 0.000
G64 Other disorders of peripheral nervous system
0.716 0.284 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.716 0.284 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.715 0.285 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.714 0.286 0.000
Y85 Sequelae of transport accidents
0.714 0.286 0.000
S68 Traumatic amputation of wrist and hand
0.714 0.286 0.000
D75 Other diseases of blood and blood-forming organs
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
G62.2 Polyneuropathy due to other toxic agents
0.712 0.288 0.000
G62.1 Alcoholic polyneuropathy
0.712 0.288 0.000
G62.0 Drug-induced polyneuropathy
0.712 0.288 0.000
J00-J06 Acute upper respiratory infections
0.712 0.288 0.000
Z45 Adjustment and management of implanted device
0.712 0.288 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.710 0.289 0.000
I00-I02 Acute rheumatic fever
0.710 0.289 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.710 0.290 0.000
Q60-Q64 Congenital malformations of the urinary system
0.710 0.290 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.709 0.291 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.709 0.291 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.709 0.291 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.709 0.291 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.709 0.291 0.000
G47.2 Disorders of the sleep-wake schedule
0.707 0.293 0.000
I78 Diseases of capillaries
0.707 0.293 0.000
W50-W64 Exposure to animate mechanical forces
0.707 0.293 0.000
M84 Disorders of continuity of bone
0.707 0.293 0.000
S71 Open wound of hip and thigh
0.706 0.294 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.706 0.294 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.705 0.295 0.000
O20.8 Other haemorrhage in early pregnancy
0.705 0.295 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
G72.9 Myopathy, unspecified
0.704 0.296 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.296 0.000
A49.1 Streptococcal infection, unspecified
0.703 0.297 0.000
J40 Bronchitis, not specified as acute or chronic
0.703 0.297 0.000
O74 Complications of anaesthesia during labour and delivery
0.702 0.298 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.702 0.298 0.000
O60 Preterm delivery
0.702 0.298 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.701 0.299 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.701 0.299 0.000
O97 Death from sequelae of direct obstetric causes
0.701 0.299 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.701 0.299 0.000
O95 Obstetric death of unspecified cause
0.701 0.299 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.701 0.299 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.700 0.300 0.000
I74.8 Embolism and thrombosis of other arteries
0.700 0.300 0.000
E11.3 With ophthalmic complications
0.700 0.300 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.699 0.301 0.000
V20-V29 Motorcycle rider injured in transport accident
0.698 0.302 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.696 0.304 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.695 0.305 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.694 0.306 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.694 0.306 0.000
A75-A79 Rickettsioses
0.694 0.306 0.000
A70-A74 Other diseases caused by chlamydiae
0.694 0.306 0.000
A65-A69 Other spirochaetal diseases
0.694 0.306 0.000
A20-A28 Certain zoonotic bacterial diseases
0.694 0.306 0.000
A15-A19 Tuberculosis
0.694 0.306 0.000
I73.0 Raynaud's syndrome
0.694 0.306 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
I20-I25 Ischaemic heart diseases
0.693 0.307 0.000
E10.0 With coma
0.693 0.307 0.000
O24 Diabetes mellitus in pregnancy
0.691 0.308 0.000
Z35.8 Supervision of other high-risk pregnancies
0.691 0.309 0.000
X20-X29 Contact with venomous animals and plants
0.691 0.309 0.000
S60 Superficial injury of wrist and hand
0.691 0.309 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.691 0.309 0.000
Z38 Liveborn infants according to place of birth
0.691 0.309 0.000
Z54 Convalescence
0.690 0.310 0.000
J95.8 Other postprocedural respiratory disorders
0.690 0.310 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.689 0.311 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.689 0.311 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.689 0.311 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.689 0.311 0.000
W22 Striking against or struck by other objects
0.689 0.311 0.000
Z22 Carrier of infectious disease
0.688 0.312 0.000
O71 Other obstetric trauma
0.687 0.313 0.000
S61.0 Open wound of finger(s) without damage to nail
0.687 0.313 0.000
M91-M94 Chondropathies
0.686 0.314 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.686 0.314 0.000
E14.3 With ophthalmic complications
0.685 0.315 0.000
V10-V19 Pedal cyclist injured in transport accident
0.684 0.316 0.000
Y52.1 Calcium-channel blockers
0.682 0.318 0.000
Z30.9 Contraceptive management, unspecified
0.682 0.318 0.000
Z30.8 Other contraceptive management
0.682 0.318 0.000
Z30.4 Surveillance of contraceptive drugs
0.682 0.318 0.000
Z30.0 General counselling and advice on contraception
0.682 0.318 0.000
E12 Malnutrition-related diabetes mellitus
0.681 0.318 0.000
G71 Primary disorders of muscles
0.681 0.319 0.000
S80.9 Superficial injury of lower leg, unspecified
0.681 0.319 0.000
B65-B83 Helminthiases
0.681 0.319 0.000
Z39.1 Care and examination of lactating mother
0.681 0.319 0.000
O33 Maternal care for known or suspected disproportion
0.680 0.320 0.000
O31 Complications specific to multiple gestation
0.680 0.320 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.680 0.320 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.678 0.322 0.000
A49.0 Staphylococcal infection, unspecified
0.678 0.322 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.677 0.323 0.000
G23 Other degenerative diseases of basal ganglia
0.677 0.323 0.000
G21 Secondary Parkinsonism
0.677 0.323 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.677 0.323 0.000
G22 Parkinsonism in diseases classified elsewhere
0.677 0.323 0.000
Y42.7 Androgens and anabolic congeners
0.677 0.323 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.676 0.323 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.675 0.325 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.673 0.327 0.000
D74 Methaemoglobinaemia
0.673 0.327 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.673 0.327 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.673 0.327 0.000
M89 Other disorders of bone
0.673 0.327 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.672 0.327 0.000
Y57 Other and unspecified drugs and medicaments
0.672 0.328 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.672 0.328 0.000
Z34 Supervision of normal pregnancy
0.671 0.329 0.000
Z35.9 Supervision of high-risk pregnancy, unspecified
0.671 0.329 0.000
Z35.7 Supervision of high-risk pregnancy due to social problems
0.671 0.329 0.000
Z35.6 Supervision of very young primigravida
0.671 0.329 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.671 0.329 0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care
0.671 0.329 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.671 0.329 0.000
M86 Osteomyelitis
0.670 0.329 0.000
G81.0 Flaccid hemiplegia
0.670 0.330 0.000
Z57 Occupational exposure to risk-factors
0.670 0.330 0.000
E14.4 With neurological complications
0.670 0.330 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.669 0.331 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.669 0.331 0.000
O75.9 Complication of labour and delivery, unspecified
0.669 0.331 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.669 0.331 0.000
O75.4 Other complications of obstetric surgery and procedures
0.669 0.331 0.000
O75.3 Other infection during labour
0.669 0.331 0.000
O75.1 Shock during or following labour and delivery
0.669 0.331 0.000
O62.3 Precipitate labour
0.669 0.331 0.000
E06 Thyroiditis
0.669 0.331 0.000
E13.9 Without complications
0.668 0.332 0.000
O29 Complications of anaesthesia during pregnancy
0.668 0.332 0.000
O28 Abnormal findings on antenatal screening of mother
0.668 0.332 0.000
O22 Venous complications in pregnancy
0.668 0.332 0.000
O25 Malnutrition in pregnancy
0.668 0.332 0.000
W06 Fall involving bed
0.668 0.332 0.000
J96 Respiratory failure, not elsewhere classified
0.667 0.333 0.000
W18 Other fall on same level
0.666 0.334 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.666 0.334 0.000
S72.1 Pertrochanteric fracture
0.666 0.334 0.000
J84 Other interstitial pulmonary diseases
0.666 0.334 0.000
M06.3 Rheumatoid nodule
0.665 0.335 0.000
T98 Sequelae of other and unspecified effects of external causes
0.665 0.335 0.000
J98.9 Respiratory disorder, unspecified
0.663 0.337 0.000
S20-S29 Injuries to the thorax
0.661 0.339 0.000
B95-B98 Bacterial, viral and other infectious agents
0.661 0.339 0.000
H61.0 Perichondritis of external ear
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.660 0.340 0.000
D55-D59 Haemolytic anaemias
0.660 0.340 0.000
Q50-Q56 Congenital malformations of genital organs
0.660 0.340 0.000
E10.5 With peripheral circulatory complications
0.659 0.341 0.000
G72.0 Drug-induced myopathy
0.659 0.341 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.659 0.341 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.658 0.342 0.000
G44.3 Chronic posttraumatic headache
0.658 0.342 0.000
G44.1 Vascular headache, not elsewhere classified
0.658 0.342 0.000
G44.0 Cluster headache syndrome
0.658 0.342 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.658 0.342 0.000
J41 Simple and mucopurulent chronic bronchitis
0.658 0.342 0.000
M60-M63 Disorders of muscles
0.657 0.342 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.657 0.343 0.000
D80-D89 Certain disorders involving the immune mechanism
0.657 0.343 0.000
S78 Traumatic amputation of hip and thigh
0.657 0.343 0.000
S77 Crushing injury of hip and thigh
0.657 0.343 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.657 0.343 0.000
S75 Injury of blood vessels at hip and thigh level
0.657 0.343 0.000
S74 Injury of nerves at hip and thigh level
0.657 0.343 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.657 0.343 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.657 0.343 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.657 0.343 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.655 0.345 0.000
G40 Epilepsy
0.655 0.345 0.000
E10.8 With unspecified complications
0.654 0.346 0.000
E10.7 With multiple complications
0.654 0.346 0.000
E10.6 With other specified complications
0.654 0.346 0.000
E10.2 With renal complications
0.654 0.346 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.654 0.346 0.000
J60-J70 Lung diseases due to external agents
0.653 0.346 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.653 0.347 0.000
M14 Arthropathies in other diseases classified elsewhere
0.652 0.348 0.000
G83 Other paralytic syndromes
0.651 0.348 0.000
Z48 Other surgical follow-up care
0.651 0.349 0.000
D72.8 Other specified disorders of white blood cells
0.651 0.349 0.000
Z45.1 Adjustment and management of infusion pump
0.651 0.349 0.000
G30 Alzheimer's disease
0.650 0.349 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.650 0.350 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.649 0.350 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.649 0.351 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.648 0.351 0.000
J98.3 Compensatory emphysema
0.648 0.351 0.000
J98.2 Interstitial emphysema
0.648 0.351 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.646 0.354 0.000
M40-M43 Deforming dorsopathies
0.645 0.355 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.645 0.355 0.000
O73 Retained placenta and membranes, without haemorrhage
0.645 0.355 0.000
Y44 Agents primarily affecting blood constituents
0.645 0.355 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.644 0.355 0.000
G03 Meningitis due to other and unspecified causes
0.644 0.356 0.000
J80 Adult respiratory distress syndrome
0.644 0.356 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.643 0.357 0.000
O21.9 Vomiting of pregnancy, unspecified
0.643 0.357 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.642 0.358 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.642 0.358 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.642 0.358 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.642 0.358 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.641 0.359 0.000
A44 Bartonellosis
0.640 0.360 0.000
A43 Nocardiosis
0.640 0.360 0.000
A42 Actinomycosis
0.640 0.360 0.000
A39 Meningococcal infection
0.640 0.360 0.000
A37 Whooping cough
0.640 0.360 0.000
A36 Diphtheria
0.640 0.360 0.000
A32 Listeriosis
0.640 0.360 0.000
A31 Infection due to other mycobacteria
0.640 0.360 0.000
A30 Leprosy [Hansen's disease]
0.640 0.360 0.000
A38 Scarlet fever
0.640 0.360 0.000
A35 Other tetanus
0.640 0.360 0.000
A34 Obstetrical tetanus
0.640 0.360 0.000
A33 Tetanus neonatorum
0.640 0.360 0.000
O45.9 Premature separation of placenta, unspecified
0.640 0.360 0.000
A02 Other Salmonella infections
0.639 0.361 0.000
W21 Striking against or struck by sports equipment
0.639 0.361 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.639 0.361 0.000
I09 Other rheumatic heart diseases
0.639 0.361 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.638 0.361 0.000
G61.1 Serum neuropathy
0.638 0.361 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.638 0.362 0.000
T20 Burn and corrosion of head and neck
0.638 0.362 0.000
G70 Myasthenia gravis and other myoneural disorders
0.638 0.362 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.638 0.362 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.638 0.362 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.638 0.362 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.638 0.362 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.638 0.362 0.000
G63.1 Polyneuropathy in neoplastic disease
0.638 0.362 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.638 0.362 0.000
Z52 Donors of organs and tissues
0.637 0.363 0.000
M00-M03 Infectious arthropathies
0.637 0.363 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.636 0.364 0.000
B34 Viral infection of unspecified site
0.636 0.364 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.635 0.365 0.000
T92 Sequelae of injuries of upper limb
0.635 0.365 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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