TreeWAS – Variant ID: rs12355831

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.3 With ophthalmic complications	0.094	0.906	0.000
E10 Insulin-dependent diabetes mellitus	0.093	0.907	0.000
E10.9 Without complications	0.090	0.910	0.000
E10.5 With peripheral circulatory complications	0.077	0.923	0.000
E10.2 With renal complications	0.077	0.923	0.000
E10.4 With neurological complications	0.073	0.927	0.000
E10.8 With unspecified complications	0.071	0.929	0.000
E10.1 With ketoacidosis	0.068	0.932	0.000
E10.7 With multiple complications	0.067	0.933	0.000
E10.0 With coma	0.067	0.933	0.000
E10.6 With other specified complications	0.067	0.933	0.000
E10-E14 Diabetes mellitus	0.042	0.958	0.000
E14 Unspecified diabetes mellitus	0.036	0.964	0.000
E14.3 With ophthalmic complications	0.032	0.968	0.000
E12 Malnutrition-related diabetes mellitus	0.030	0.970	0.000
E14.4 With neurological complications	0.029	0.971	0.000
E13 Other specified diabetes mellitus	0.027	0.973	0.000
E14.8 With unspecified complications	0.026	0.974	0.000
E14.7 With multiple complications	0.026	0.974	0.000
E14.6 With other specified complications	0.026	0.974	0.000
E14.5 With peripheral circulatory complications	0.026	0.974	0.000
E14.2 Withrenal complications	0.026	0.974	0.000
E14.1 With ketoacidosis	0.026	0.974	0.000
E14.0 With coma	0.026	0.974	0.000
E14.9 Without complications	0.025	0.975	0.000
E12.9 Without complications	0.022	0.978	0.000
E12.8 With unspecified complications	0.022	0.978	0.000
E12.7 With multiple complications	0.022	0.978	0.000
E12.6 With other specified complications	0.022	0.978	0.000
E12.5 With peripheral circulatory complications	0.022	0.978	0.000
E12.4 With neurological complications	0.022	0.978	0.000
E12.3 With ophthalmic complications	0.022	0.978	0.000
E12.2 With renal complications	0.022	0.978	0.000
E12.1 With ketoacidosis	0.022	0.978	0.000
E12.0 With coma	0.022	0.978	0.000
E11 Non-insulin-dependent diabetes mellitus	0.022	0.978	0.000
E11.8 With unspecified complications	0.020	0.980	0.000
E13.8 With unspecified complications	0.019	0.980	0.000
E13.7 With multiple complications	0.019	0.980	0.000
E13.6 With other specified complications	0.019	0.980	0.000
E13.5 With peripheral circulatory complications	0.019	0.980	0.000
E13.4 With neurological complications	0.019	0.980	0.000
E13.3 With ophthalmic complications	0.019	0.980	0.000
E13.2 With renal complications	0.019	0.980	0.000
E13.1 With ketoacidosis	0.019	0.980	0.000
E13.0 With coma	0.019	0.980	0.000
E11.0 With coma	0.019	0.981	0.000
E11.2 With renal complications	0.019	0.981	0.000
E13.9 Without complications	0.016	0.984	0.000
E11.7 With multiple complications	0.016	0.984	0.000
E11.6 With other specified complications	0.015	0.984	0.000
E11.1 With ketoacidosis	0.015	0.985	0.000
E11.5 With peripheral circulatory complications	0.015	0.985	0.000
J32.9 Chronic sinusitis, unspecified	0.013	0.987	0.000
E55.9 Vitamin D deficiency, unspecified	0.009	0.991	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.009	0.991	0.000
E55 Vitamin D deficiency	0.009	0.991	0.000
E11.9 Without complications	0.008	0.992	0.000
T88.4 Failed or difficult intubation	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.008	0.992	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.008	0.992	0.000
E22.0 Acromegaly and pituitary gigantism	0.008	0.992	0.000
E22 Hyperfunction of pituitary gland	0.007	0.993	0.000
R73.9 Hyperglycaemia, unspecified	0.007	0.993	0.000
E51 Thiamine deficiency	0.007	0.993	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.007	0.993	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.007	0.993	0.000
E20-E35 Disorders of other endocrine glands	0.007	0.993	0.000
E55.0 Rickets, active	0.006	0.994	0.000
E53 Deficiency of other B group vitamins	0.006	0.994	0.000
E51.2 Wernicke's encephalopathy	0.006	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.006	0.994	0.000
E56 Other vitamin deficiencies	0.006	0.994	0.000
E50 Vitamin A deficiency	0.006	0.994	0.000
E60 Dietary zinc deficiency	0.006	0.994	0.000
E59 Dietary selenium deficiency	0.006	0.994	0.000
E58 Dietary calcium deficiency	0.006	0.994	0.000
E54 Ascorbic acid deficiency	0.006	0.994	0.000
E52 Niacin deficiency [pellagra]	0.006	0.994	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.006	0.994	0.000
E16 Other disorders of pancreatic internal secretion	0.006	0.994	0.000
R73 Elevated blood glucose level	0.006	0.994	0.000
D12.6 Colon, unspecified	0.006	0.994	0.000
E11.4 With neurological complications	0.005	0.994	0.000
R73.0 Abnormal glucose tolerance test	0.006	0.994	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.005	0.995	0.000
E22.8 Other hyperfunction of pituitary gland	0.005	0.995	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.005	0.995	0.000
E40-E46 Malnutrition	0.005	0.995	0.000
E16.2 Hypoglycaemia, unspecified	0.005	0.995	0.000
E34 Other endocrine disorders	0.005	0.995	0.000
E51.9 Thiamine deficiency, unspecified	0.005	0.995	0.000
E51.8 Other manifestations of thiamine deficiency	0.005	0.995	0.000
E51.1 Beriberi	0.005	0.995	0.000
T88.9 Complication of surgical and medical care, unspecified	0.005	0.995	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.005	0.995	0.000
T88.2 Shock due to anaesthesia	0.005	0.995	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.005	0.995	0.000
T88.0 Infection following immunisation	0.005	0.995	0.000
E28 Ovarian dysfunction	0.005	0.995	0.000
E15 Nondiabetic hypoglycaemic coma	0.005	0.995	0.000
E20 Hypoparathyroidism	0.005	0.995	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E32 Diseases of thymus	0.005	0.995	0.000
E31 Polyglandular dysfunction	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
E25 Adrenogenital disorders	0.005	0.995	0.000
E11.3 With ophthalmic complications	0.005	0.995	0.000
E24 Cushing's syndrome	0.005	0.995	0.000
E61 Deficiency of other nutrient elements	0.005	0.995	0.000
E27 Other disorders of adrenal gland	0.005	0.995	0.000
E22.1 Hyperprolactinaemia	0.005	0.995	0.000
E26 Hyperaldosteronism	0.005	0.995	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.005	0.995	0.000
E23 Hypofunction and other disorders of pituitary gland	0.005	0.995	0.000
E53.8 Deficiency of other specified B group vitamins	0.005	0.995	0.000
E53.9 Vitamin B deficiency, unspecified	0.005	0.995	0.000
E53.1 Pyridoxine deficiency	0.005	0.995	0.000
E53.0 Riboflavin deficiency	0.005	0.995	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.005	0.995	0.000
E50.9 Vitamin A deficiency, unspecified	0.005	0.995	0.000
E50.8 Other manifestations of vitamin A deficiency	0.005	0.995	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.005	0.995	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.005	0.995	0.000
E50.5 Vitamin A deficiency with night blindness	0.005	0.995	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.005	0.995	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.005	0.995	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.005	0.995	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.005	0.995	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.005	0.995	0.000
E56.9 Vitamin deficiency, unspecified	0.005	0.995	0.000
E56.8 Deficiency of other vitamins	0.005	0.995	0.000
E56.1 Deficiency of vitamin K	0.005	0.995	0.000
E56.0 Deficiency of vitamin E	0.005	0.995	0.000
E63.9 Nutritional deficiency, unspecified	0.005	0.995	0.000
E63.8 Other specified nutritional deficiencies	0.005	0.995	0.000
E63.1 Imbalance of constituents of food intake	0.005	0.995	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.005	0.995	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.005	0.995	0.000
E64.8 Sequelae of other nutritional deficiencies	0.005	0.995	0.000
E64.3 Sequelae of rickets	0.005	0.995	0.000
E64.2 Sequelae of vitamin C deficiency	0.005	0.995	0.000
E64.1 Sequelae of vitamin A deficiency	0.005	0.995	0.000
E64.0 Sequelae of protein-energy malnutrition	0.005	0.995	0.000
Z04.8 Examination and observation for other specified reasons	0.005	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.995	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.004	0.995	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.004	0.995	0.000
E16.4 Abnormal secretion of gastrin	0.004	0.995	0.000
E16.3 Increased secretion of glucagon	0.004	0.995	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.004	0.996	0.000
E16.1 Other hypoglycaemia	0.004	0.996	0.000
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.996	0.000
E34.0 Carcinoid syndrome	0.004	0.996	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.004	0.996	0.000
E45 Retarded development following protein-energy malnutrition	0.004	0.996	0.000
E43 Unspecified severe protein-energy malnutrition	0.004	0.996	0.000
E42 Marasmic kwashiorkor	0.004	0.996	0.000
E41 Nutritional marasmus	0.004	0.996	0.000
E40 Kwashiorkor	0.004	0.996	0.000
E34.5 Androgen resistance syndrome	0.004	0.996	0.000
E34.4 Constitutional tall stature	0.004	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.004	0.996	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.996	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.996	0.000
B18.2 Chronic viral hepatitis C	0.004	0.996	0.000
E24.2 Drug-induced Cushing's syndrome	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
G97.8 Other postprocedural disorders of nervous system	0.004	0.996	0.000
E28.9 Ovarian dysfunction, unspecified	0.004	0.996	0.000
E28.8 Other ovarian dysfunction	0.004	0.996	0.000
E28.1 Androgen excess	0.004	0.996	0.000
E28.0 Oestrogen excess	0.004	0.996	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.004	0.996	0.000
T88.5 Other complications of anaesthesia	0.004	0.996	0.000
E20.9 Hypoparathyroidism, unspecified	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.004	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.004	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.004	0.996	0.000
E25.8 Other adrenogenital disorders	0.004	0.996	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.004	0.996	0.000
E30.9 Disorder of puberty, unspecified	0.004	0.996	0.000
E30.8 Other disorders of puberty	0.004	0.996	0.000
E30.1 Precocious puberty	0.004	0.996	0.000
E30.0 Delayed puberty	0.004	0.996	0.000
E31.9 Polyglandular dysfunction, unspecified	0.004	0.996	0.000
E31.8 Other polyglandular dysfunction	0.004	0.996	0.000
E31.1 Polyglandular hyperfunction	0.004	0.996	0.000
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
E32.9 Disease of thymus, unspecified	0.004	0.996	0.000
E32.8 Other diseases of thymus	0.004	0.996	0.000
E32.1 Abscess of thymus	0.004	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.996	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
E24.8 Other Cushing's syndrome	0.004	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.004	0.996	0.000
E24.3 Ectopic ACTH syndrome	0.004	0.996	0.000
E24.1 Nelson's syndrome	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.996	0.000
E27.5 Adrenomedullary hyperfunction	0.004	0.996	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.004	0.996	0.000
E27.0 Other adrenocortical overactivity	0.004	0.996	0.000
E61.9 Deficiency of nutrient element, unspecified	0.004	0.996	0.000
E61.8 Deficiency of other specified nutrient elements	0.004	0.996	0.000
E61.7 Deficiency of multiple nutrient elements	0.004	0.996	0.000
E61.6 Vanadium deficiency	0.004	0.996	0.000
E61.5 Molybdenum deficiency	0.004	0.996	0.000
E61.4 Chromium deficiency	0.004	0.996	0.000
E61.3 Manganese deficiency	0.004	0.996	0.000
E61.2 Magnesium deficiency	0.004	0.996	0.000
E61.0 Copper deficiency	0.004	0.996	0.000
E23.6 Other disorders of pituitary gland	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.996	0.000
E26.8 Other hyperaldosteronism	0.004	0.996	0.000
E26.1 Secondary hyperaldosteronism	0.004	0.996	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.004	0.996	0.000
G90-G99 Other disorders of the nervous system	0.004	0.996	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.996	0.000
E23.2 Diabetes insipidus	0.004	0.996	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.996	0.000
B18 Chronic viral hepatitis	0.004	0.996	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.004	0.996	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.996	0.004
E04.2 Non-toxic multinodular goitre	0.004	0.996	0.000
G90 Disorders of autonomic nervous system	0.004	0.996	0.000
E27.2 Addisonian crisis	0.003	0.996	0.000
E28.3 Primary ovarian failure	0.003	0.996	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.996	0.000
I84.5 External haemorrhoids without complication	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.003	0.996	0.000
B17.1 Acute hepatitis C	0.003	0.996	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.003	0.996	0.000
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.003	0.997	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.003	0.997	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.003	0.997	0.000
A41.8 Other specified septicaemia	0.003	0.997	0.000
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.997	0.000
E29.8 Other testicular dysfunction	0.003	0.997	0.000
E29.0 Testicular hyperfunction	0.003	0.997	0.000
G90.2 Horner's syndrome	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
E44.1 Mild protein-energy malnutrition	0.003	0.997	0.000
E44.0 Moderate protein-energy malnutrition	0.003	0.997	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.003	0.997	0.000
J32.2 Chronic ethmoidal sinusitis	0.003	0.997	0.000
E23.0 Hypopituitarism	0.003	0.997	0.000
B17 Other acute viral hepatitis	0.003	0.997	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.003	0.997	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.003	0.997	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.003	0.997	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.003	0.997	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.003	0.997	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
E65-E68 Obesity and other hyperalimentation	0.003	0.997	0.000
G96 Other disorders of central nervous system	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.003	0.997	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.997	0.003
G91 Hydrocephalus	0.003	0.997	0.000
G92 Toxic encephalopathy	0.003	0.997	0.000
B15-B19 Viral hepatitis	0.003	0.997	0.000
B18.9 Chronic viral hepatitis, unspecified	0.003	0.997	0.000
B18.8 Other chronic viral hepatitis	0.003	0.997	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.003	0.997	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.003	0.997	0.000
E04 Other non-toxic goitre	0.003	0.997	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.003	0.997	0.000
J32 Chronic sinusitis	0.003	0.997	0.000
G90.8 Other disorders of autonomic nervous system	0.003	0.997	0.000
G90.4 Autonomic dysreflexia	0.003	0.997	0.000
G90.3 Multisystem degeneration	0.003	0.997	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.997	0.003
G91.9 Hydrocephalus, unspecified	0.003	0.997	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.003	0.997	0.000
G95 Other diseases of spinal cord	0.003	0.997	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.003	0.997	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.003	0.997	0.000
S61.0 Open wound of finger(s) without damage to nail	0.000	0.997	0.003
I80 Phlebitis and thrombophlebitis	0.003	0.997	0.000
E61.1 Iron deficiency	0.002	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.997	0.000
E21.2 Other hyperparathyroidism	0.002	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.997	0.000
A41 Other septicaemia	0.003	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
B17.9 Acute viral hepatitis, unspecified	0.002	0.997	0.000
B17.8 Other specified acute viral hepatitis	0.002	0.997	0.000
B17.2 Acute hepatitis E	0.002	0.997	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.002	0.997	0.000
G95.0 Syringomyelia and syringobulbia	0.002	0.997	0.000
B16 Acute hepatitis B	0.002	0.997	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.003	0.997	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.997	0.003
Y86 Sequelae of other accidents	0.003	0.997	0.000
E29.1 Testicular hypofunction	0.002	0.997	0.000
R77 Other abnormalities of plasma proteins	0.002	0.997	0.000
G54.0 Brachial plexus disorders	0.002	0.997	0.000
G95.2 Cord compression, unspecified	0.002	0.997	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.003	0.997	0.000
E67 Other hyperalimentation	0.002	0.997	0.000
E68 Sequelae of hyperalimentation	0.002	0.997	0.000
H11.0 Pterygium	0.000	0.997	0.002
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
R76 Other abnormal immunological findings in serum	0.002	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.002	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
B19 Unspecified viral hepatitis	0.002	0.998	0.000
G91.8 Other hydrocephalus	0.002	0.998	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.002	0.998	0.000
G91.0 Communicating hydrocephalus	0.002	0.998	0.000
G96.0 Cerebrospinal fluid leak	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
R59.9 Enlarged lymph nodes, unspecified	0.002	0.998	0.000
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.002	0.998	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
G91.2 Normal-pressure hydrocephalus	0.002	0.998	0.000
G94.1 Hydrocephalus in neoplastic disease	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.002	0.998	0.000
R03.1 Nonspecific low blood-pressure reading	0.000	0.998	0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.998	0.000
G93 Other disorders of brain	0.002	0.998	0.000
E04.1 Non-toxic single thyroid nodule	0.002	0.998	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.002	0.998	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.998	0.002
B15 Acute hepatitis A	0.002	0.998	0.000
R77.9 Abnormality of plasma protein, unspecified	0.002	0.998	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.002	0.998	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.002	0.998	0.000
R71 Abnormality of red blood cells	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.998	0.002
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
J32.1 Chronic frontal sinusitis	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.000	0.998	0.002
G95.1 Vascular myelopathies	0.002	0.998	0.000
R74 Abnormal serum enzyme levels	0.002	0.998	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.002	0.998	0.000
A41.4 Septicaemia due to anaerobes	0.002	0.998	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.002	0.998	0.000
G62 Other polyneuropathies	0.000	0.998	0.002
J00 Acute nasopharyngitis [common cold]	0.002	0.998	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.002	0.998	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.002	0.998	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.002	0.998	0.000
R77.8 Other specified abnormalities of plasma proteins	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.002	0.998	0.000
E67.3 Hypervitaminosis D	0.002	0.998	0.000
E67.2 Megavitamin-B6 syndrome	0.002	0.998	0.000
E67.1 Hypercarotenaemia	0.002	0.998	0.000
E67.0 Hypervitaminosis A	0.002	0.998	0.000
R77.2 Abnormality of alphafetoprotein	0.002	0.998	0.000
R77.1 Abnormality of globulin	0.002	0.998	0.000
R77.0 Abnormality of albumin	0.002	0.998	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.002	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.002	0.998	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.002	0.998	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.002	0.998	0.000
B19.9 Unspecified viral hepatitis without coma	0.002	0.998	0.000
B19.0 Unspecified viral hepatitis with coma	0.002	0.998	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.002	0.998	0.000
R76.2 False-positive serological test for syphilis	0.002	0.998	0.000
R76.1 Abnormal reaction to tuberculin test	0.002	0.998	0.000
R76.0 Raised antibody titer	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
E06 Thyroiditis	0.001	0.998	0.001
H73 Other disorders of tympanic membrane	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
E07 Other disorders of thyroid	0.002	0.998	0.000
G93.5 Compression of brain	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
G93.7 Reye's syndrome	0.002	0.998	0.000
G91.1 Obstructive hydrocephalus	0.002	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.002	0.998	0.000
B15.0 Hepatitis A with hepatic coma	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.002	0.998	0.000
J93.9 Pneumothorax, unspecified	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.002	0.998	0.000
H11 Other disorders of conjunctiva	0.000	0.998	0.002
G93.2 Benign intracranial hypertension	0.002	0.998	0.000
E65 Localised adiposity	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.002	0.998	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.002	0.998	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.002	0.998	0.000
R78.6 Finding of steroid agent in blood	0.002	0.998	0.000
R78.5 Finding of psychotropic drug in blood	0.002	0.998	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.002	0.998	0.000
R78.3 Finding of hallucinogen in blood	0.002	0.998	0.000
R78.2 Finding of cocaine in blood	0.002	0.998	0.000
R78.1 Finding of opiate drug in blood	0.002	0.998	0.000
R78.0 Finding of alcohol in blood	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.002	0.998	0.000
J32.4 Chronic pansinusitis	0.002	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.998	0.002
R74.9 Abnormal level of unspecified serum enzyme	0.002	0.998	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.002	0.998	0.000
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
S61 Open wound of wrist and hand	0.000	0.998	0.002
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
G62.2 Polyneuropathy due to other toxic agents	0.000	0.998	0.002
G62.1 Alcoholic polyneuropathy	0.000	0.998	0.002
G62.0 Drug-induced polyneuropathy	0.000	0.998	0.002
J32.8 Other chronic sinusitis	0.002	0.998	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
B15.9 Hepatitis A without hepatic coma	0.002	0.998	0.000
H57.1 Ocular pain	0.000	0.998	0.002
Z49.1 Extracorporeal dialysis	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
R41.3 Other amnesia	0.000	0.998	0.002
A40 Streptococcal septicaemia	0.002	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.002	0.998	0.000
R70.1 Abnormal plasma viscosity	0.002	0.998	0.000
A30-A49 Other bacterial diseases	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
M45 Ankylosing spondylitis	0.002	0.998	0.000
A40.0 Septicaemia due to streptococcus, group A	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.001	0.998	0.001
E06.4 Drug-induced thyroiditis	0.001	0.998	0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.001	0.998	0.001
E06.1 Subacute thyroiditis	0.001	0.998	0.001
E06.0 Acute thyroiditis	0.001	0.998	0.001
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.998	0.002
H73.1 Chronic myringitis	0.000	0.998	0.002
H73.0 Acute myringitis	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.001	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.001	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
I80.8 Phlebitis and thrombophlebitis of other sites	0.002	0.998	0.000
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
H11.2 Conjunctival scars	0.000	0.998	0.001
N13 Obstructive and reflux uropathy	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.001	0.998	0.001
G93.8 Other specified disorders of brain	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.998	0.000
H11.3 Conjunctival haemorrhage	0.000	0.998	0.002
G54 Nerve root and plexus disorders	0.002	0.998	0.000
Z41 Procedures for purposes other than remedying health state	0.000	0.998	0.002
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.002	0.998	0.000
A48 Other bacterial diseases, not elsewhere classified	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.001	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.001	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.001	0.998	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.001
H58.1 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.001
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations