TreeWAS – Variant ID: rs12408810

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C16 Malignant neoplasm of stomach	0.109	0.891	0.000
C18 Malignant neoplasm of colon	0.107	0.893	0.000
C16.9 Stomach, unspecified	0.106	0.894	0.000
C18.4 Transverse colon	0.104	0.896	0.000
C18.9 Colon, unspecified	0.103	0.897	0.000
C16.0 Cardia	0.101	0.899	0.000
C18.2 Ascending colon	0.100	0.900	0.000
C15-C26 Malignant neoplasms of digestive organs	0.099	0.901	0.000
C18.0 Caecum	0.089	0.911	0.000
C16.3 Pyloric antrum	0.089	0.911	0.000
C18.8 Overlapping lesion of colon	0.087	0.913	0.000
C18.5 Splenic flexure	0.086	0.914	0.000
C16.1 Fundus of stomach	0.086	0.914	0.000
C16.6 Greater curvature of stomach, unspecified	0.083	0.917	0.000
C16.2 Body of stomach	0.082	0.918	0.000
C16.5 Lesser curvature of stomach, unspecified	0.081	0.919	0.000
C18.3 Hepatic flexure	0.080	0.920	0.000
C17 Malignant neoplasm of small intestine	0.080	0.920	0.000
C16.8 Overlapping lesion of stomach	0.078	0.922	0.000
C16.4 Pylorus	0.078	0.922	0.000
C25 Malignant neoplasm of pancreas	0.077	0.923	0.000
C21 Malignant neoplasm of anus and anal canal	0.074	0.926	0.000
C18.1 Appendix	0.073	0.927	0.000
C23 Malignant neoplasm of gallbladder	0.072	0.928	0.000
C15 Malignant neoplasm of oesophagus	0.068	0.932	0.000
C17.9 Small intestine, unspecified	0.066	0.934	0.000
C25.0 Head of pancreas	0.065	0.935	0.000
C17.1 Jejunum	0.065	0.935	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.063	0.937	0.000
C15.9 Oesophagus, unspecified	0.062	0.938	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.062	0.938	0.000
C21.1 Anal canal	0.062	0.938	0.000
C25.3 Pancreatic duct	0.060	0.940	0.000
C25.1 Body of pancreas	0.058	0.942	0.000
C17.8 Overlapping lesion of small intestine	0.057	0.942	0.000
C17.3 Meckel's diverticulum	0.057	0.942	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.057	0.943	0.000
C17.0 Duodenum	0.057	0.943	0.000
C25.8 Overlapping lesion of pancreas	0.055	0.944	0.000
C25.7 Other parts of pancreas	0.055	0.944	0.000
C25.4 Endocrine pancreas	0.055	0.944	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.053	0.946	0.000
C21.2 Cloacogenic zone	0.053	0.946	0.000
C20 Malignant neoplasm of rectum	0.052	0.948	0.000
C25.9 Pancreas, unspecified	0.050	0.950	0.000
C15.8 Overlapping lesion of oesophagus	0.049	0.951	0.000
C15.2 Abdominal part of oesophagus	0.049	0.951	0.000
C15.1 Thoracic part of oesophagus	0.049	0.951	0.000
C15.0 Cervical part of oesophagus	0.049	0.951	0.000
C15.3 Upper third of oesophagus	0.048	0.952	0.000
C17.2 Ileum	0.048	0.952	0.000
Z87.4 Personal history of diseases of the genito-urinary system	0.047	0.953	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.047	0.953	0.000
C21.0 Anus, unspecified	0.046	0.954	0.000
C26.9 Ill-defined sites within the digestive system	0.045	0.954	0.000
C26.8 Overlapping lesion of digestive system	0.045	0.954	0.000
C26.1 Spleen	0.045	0.954	0.000
C24.9 Biliary tract, unspecified	0.044	0.955	0.000
C24.8 Overlapping lesion of biliary tract	0.044	0.955	0.000
C24.0 Extrahepatic bile duct	0.044	0.955	0.000
C25.2 Tail of pancreas	0.044	0.956	0.000
C22.7 Other specified carcinomas of liver	0.041	0.959	0.000
C22.4 Other sarcomas of liver	0.041	0.959	0.000
C22.3 Angiosarcoma of liver	0.041	0.959	0.000
C22.2 Hepatoblastoma	0.041	0.959	0.000
C22.9 Liver, unspecified	0.041	0.959	0.000
C22.0 Liver cell carcinoma	0.039	0.961	0.000
C26.0 Intestinal tract, part unspecified	0.038	0.962	0.000
C24.1 Ampulla of Vater	0.035	0.965	0.000
C15.5 Lower third of oesophagus	0.035	0.965	0.000
C18.6 Descending colon	0.033	0.966	0.001
C15.4 Middle third of oesophagus	0.032	0.968	0.000
C22.1 Intrahepatic bile duct carcinoma	0.031	0.969	0.000
I12.0 Hypertensive renal disease with renal failure	0.026	0.974	0.000
I12 Hypertensive renal disease	0.022	0.978	0.000
I12.9 Hypertensive renal disease without renal failure	0.021	0.979	0.000
G40.9 Epilepsy, unspecified	0.000	0.986	0.014
N13.3 Other and unspecified hydronephrosis	0.013	0.987	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.987	0.013
G40 Epilepsy	0.000	0.987	0.013
C18.7 Sigmoid colon	0.012	0.987	0.000
G40.8 Other epilepsy	0.000	0.989	0.011
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.989	0.011
N13.8 Other obstructive and reflux uropathy	0.010	0.990	0.000
Z71.8 Other specified counselling	0.000	0.990	0.010
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.990	0.010
N13 Obstructive and reflux uropathy	0.010	0.990	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.990	0.009
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.990	0.009
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.990	0.009
G40.5 Special epileptic syndromes	0.000	0.991	0.009
N13.7 Vesicoureteral-reflux-associated uropathy	0.008	0.991	0.000
D48.5 Skin	0.008	0.992	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.008	0.992	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.008	0.992	0.000
N13.4 Hydroureter	0.007	0.993	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.993	0.007
N13.5 Kinking and stricture of ureter without hydronephrosis	0.007	0.993	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.006	0.994	0.000
N28.1 Cyst of kidney, acquired	0.006	0.994	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.006	0.994	0.000
N13.6 Pyonephrosis	0.006	0.994	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.006	0.994	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.005	0.995	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.005	0.995	0.000
N28.8 Other specified disorders of kidney and ureter	0.005	0.995	0.000
Q21.1 Atrial septal defect	0.000	0.995	0.005
D48.1 Connective and other soft tissue	0.005	0.995	0.000
D48.7 Other specified sites	0.005	0.995	0.000
N28.0 Ischaemia and infarction of kidney	0.005	0.995	0.000
B02.9 Zoster without complication	0.004	0.995	0.000
H53.8 Other visual disturbances	0.004	0.996	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.004	0.996	0.000
D48.4 Peritoneum	0.004	0.996	0.000
D48.3 Retroperitoneum	0.004	0.996	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.004	0.996	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.004	0.996	0.000
D48.6 Breast	0.004	0.996	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.996	0.004
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.004	0.996	0.000
N88.2 Stricture and stenosis of cervix uteri	0.004	0.996	0.000
D48.0 Bone and articular cartilage	0.003	0.996	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
L90.5 Scar conditions and fibrosis of skin	0.000	0.997	0.003
M25.77 Osteophyte (Ankle and foot)	0.000	0.997	0.003
M67.8 Other specified disorders of synovium and tendon	0.000	0.997	0.003
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.997	0.003
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.997	0.003
N88 Other noninflammatory disorders of cervix uteri	0.003	0.997	0.000
I10-I15 Hypertensive diseases	0.003	0.997	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.003	0.997	0.000
K65.0 Acute peritonitis	0.000	0.997	0.003
Q21 Congenital malformations of cardiac septa	0.000	0.997	0.003
Z43.6 Attention to other artificial openings of urinary tract	0.003	0.997	0.000
B02 Zoster [herpes zoster]	0.003	0.997	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.997	0.003
D25.2 Subserosal leiomyoma of uterus	0.003	0.997	0.000
L30.9 Dermatitis, unspecified	0.003	0.997	0.000
H53.2 Diplopia	0.003	0.997	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.003	0.997	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.003	0.997	0.000
D37.6 Liver, gallbladder and bile ducts	0.003	0.997	0.000
N88.4 Hypertrophic elongation of cervix uteri	0.002	0.997	0.000
N88.3 Incompetence of cervix uteri	0.002	0.997	0.000
N88.0 Leukoplakia of cervix uteri	0.002	0.997	0.000
G59.0 Diabetic mononeuropathy	0.000	0.997	0.003
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
H53 Visual disturbances	0.003	0.997	0.000
D37.7 Other digestive organs	0.003	0.997	0.000
D39.1 Ovary	0.002	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.997	0.003
I13 Hypertensive heart and renal disease	0.002	0.997	0.000
I11 Hypertensive heart disease	0.002	0.997	0.000
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
D39.0 Uterus	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
F17.2 Dependence syndrome	0.000	0.998	0.002
H53.9 Visual disturbance, unspecified	0.002	0.998	0.000
N88.1 Old laceration of cervix uteri	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.998	0.002
Q21.8 Other congenital malformations of cardiac septa	0.000	0.998	0.002
Q21.4 Aortopulmonary septal defect	0.000	0.998	0.002
Q21.3 Tetralogy of Fallot	0.000	0.998	0.002
Q21.2 Atrioventricular septal defect	0.000	0.998	0.002
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.000	0.998	0.002
B02.8 Zoster with other complications	0.002	0.998	0.000
B02.7 Disseminated zoster	0.002	0.998	0.000
B02.1 Zoster meningitis	0.002	0.998	0.000
B02.0 Zoster encephalitis	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
I15 Secondary hypertension	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
K65.8 Other peritonitis	0.000	0.998	0.002
D40.1 Testis	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.000	0.998	0.002
N25-N29 Other disorders of kidney and ureter	0.002	0.998	0.000
B02.3 Zoster ocular disease	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
H53.6 Night blindness	0.002	0.998	0.000
H53.5 Colour vision deficiencies	0.002	0.998	0.000
H53.3 Other disorders of binocular vision	0.002	0.998	0.000
K65 Peritonitis	0.000	0.998	0.002
B00.5 Herpesviral ocular disease	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.002	0.998	0.000
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
D38.5 Other respiratory organs	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.002	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.002
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
D40.9 Male genital organ, unspecified	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.000	0.998	0.002
Z71.5 Drug abuse counselling and surveillance	0.000	0.998	0.002
Z71.4 Alcohol abuse counselling and surveillance	0.000	0.998	0.002
Z71.2 Person consulting for explanation of investigation findings	0.000	0.998	0.002
Z71.0 Person consulting on behalf of another person	0.000	0.998	0.002
D40.0 Prostate	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.998	0.000
L30 Other dermatitis	0.002	0.998	0.000
D37.3 Appendix	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.002	0.998	0.000
D38.4 Thymus	0.002	0.998	0.000
D38.3 Mediastinum	0.002	0.998	0.000
D38.2 Pleura	0.002	0.998	0.000
D38.0 Larynx	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.002	0.998	0.000
D42.1 Spinal meninges	0.002	0.998	0.000
D42.0 Cerebral meninges	0.002	0.998	0.000
I15.8 Other secondary hypertension	0.002	0.998	0.000
I15.2 Hypertension secondary to endocrine disorders	0.002	0.998	0.000
I15.0 Renovascular hypertension	0.002	0.998	0.000
B00.8 Other forms of herpesviral infection	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.002
L30.3 Infective dermatitis	0.002	0.998	0.000
B00 Herpesviral [herpes simplex] infections	0.002	0.998	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
N25 Disorders resulting from impaired renal tubular function	0.002	0.998	0.000
M25.71 Osteophyte (Shoulder region)	0.000	0.998	0.002
E07.9 Disorder of thyroid, unspecified	0.000	0.998	0.002
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
M67.1 Other contracture of tendon (sheath)	0.000	0.998	0.002
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.002	0.998	0.000
H53-H54 Visual disturbances and blindness	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.000	0.998	0.002
R16.1 Splenomegaly, not elsewhere classified	0.002	0.998	0.000
B08.1 Molluscum contagiosum	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.002	0.998	0.000
H54.5 Low vision, one eye	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
Z48.8 Other specified surgical follow-up care	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.000	0.998	0.002
N27 Small kidney of unknown cause	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
N25.1 Nephrogenic diabetes insipidus	0.002	0.998	0.000
Z71.3 Dietary counselling and surveillance	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.002
I15.9 Seconday hypertension, unspecified	0.001	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
D44.8 Pluriglandular involvement	0.001	0.998	0.000
G41.9 Status epilepticus, unspecified	0.000	0.998	0.002
L30.5 Pityriasis alba	0.002	0.998	0.000
L30.4 Erythema intertrigo	0.002	0.998	0.000
L30.2 Cutaneous autosensitisation	0.002	0.998	0.000
L30.1 Dyshidrosis [pompholyx]	0.002	0.998	0.000
L30.0 Nummular dermatitis	0.002	0.998	0.000
D44.9 Endocrine gland, unspecified	0.001	0.998	0.000
D44.7 Aortic body and other paraganglia	0.001	0.998	0.000
D44.6 Carotid body	0.001	0.998	0.000
D44.5 Pineal gland	0.001	0.998	0.000
D44.2 Parathyroid gland	0.001	0.998	0.000
D44.0 Thyroid gland	0.001	0.998	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.000	0.998	0.002
D43.9 Central nervous system, unspecified	0.001	0.998	0.000
D43.7 Other parts of central nervous system	0.001	0.998	0.000
D43.4 Spinal cord	0.001	0.998	0.000
D43.3 Cranial nerves	0.001	0.998	0.000
D43.1 Brain, infratentorial	0.001	0.998	0.000
N10-N16 Renal tubulo-interstitial diseases	0.002	0.998	0.000
D44.1 Adrenal gland	0.001	0.998	0.000
G30.8 Other Alzheimer's disease	0.000	0.998	0.001
L30.8 Other specified dermatitis	0.002	0.998	0.000
B00.7 Disseminated herpesviral disease	0.001	0.998	0.000
B00.3 Herpesviral meningitis	0.001	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.001	0.998	0.000
B00.0 Eczema herpeticum	0.001	0.998	0.000
D38.1 Trachea, bronchus and lung	0.001	0.998	0.000
D41.9 Urinary organ, unspecified	0.001	0.998	0.000
D41.7 Other urinary organs	0.001	0.998	0.000
D41.3 Urethra	0.001	0.998	0.000
D41.2 Ureter	0.001	0.998	0.000
D41.1 Renal pelvis	0.001	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.001	0.998	0.000
N25.0 Renal osteodystrophy	0.001	0.998	0.000
Z71.6 Tobacco abuse counselling	0.000	0.998	0.001
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.002	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.001	0.998	0.000
L25.9 Unspecified contact dermatitis, unspecified cause	0.002	0.998	0.000
N93.0 Postcoital and contact bleeding	0.000	0.998	0.002
B00.4 Herpesviral encephalitis	0.001	0.998	0.000
D43.2 Brain, unspecified	0.001	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.001	0.998	0.000
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
N29.0 Late syphilis of kidney	0.001	0.998	0.000
O21.2 Late vomiting of pregnancy	0.001	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
D44.4 Craniopharyngeal duct	0.001	0.998	0.000
H53.1 Subjective visual disturbances	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.998	0.001
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
M25.7 Osteophyte	0.000	0.998	0.002
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.998	0.001
M67.4 Ganglion	0.000	0.998	0.001
M67.3 Transient synovitis	0.000	0.998	0.001
M67.0 Short Achilles tendon (acquired)	0.000	0.998	0.001
N27.9 Small kidney, unspecified	0.001	0.998	0.000
N27.1 Small kidney, bilateral	0.001	0.998	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.001	0.998	0.000
D41.0 Kidney	0.001	0.998	0.000
H40.0 Glaucoma suspect	0.002	0.998	0.000
N15 Other renal tubulo-interstitial diseases	0.001	0.998	0.000
D10.1 Tongue	0.001	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.001	0.998	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.001	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.998	0.001
I33.0 Acute and subacute infective endocarditis	0.001	0.998	0.000
N27.0 Small kidney, unilateral	0.001	0.998	0.000
O21 Excessive vomiting in pregnancy	0.001	0.998	0.000
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.001	0.999	0.000
B08.5 Enteroviral vesicular pharyngitis	0.001	0.999	0.000
B08.4 Enteroviral vesicular stomatitis with exanthem	0.001	0.999	0.000
B08.3 Erythema infectiosum [fifth disease]	0.001	0.999	0.000
B08.2 Exanthema subitum [sixth disease]	0.001	0.999	0.000
B08.0 Other orthopoxvirus infections	0.001	0.999	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.001	0.999	0.000
T90.9 Sequelae of unspecified injury of head	0.001	0.999	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.999	0.001
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.999	0.001
D44.3 Pituitary gland	0.001	0.999	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.999	0.001
O36.8 Maternal care for other specified foetal problems	0.001	0.999	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.001	0.999	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.001	0.999	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.001	0.999	0.000
L29.2 Pruritus vulvae	0.001	0.999	0.000
R09.1 Pleurisy	0.001	0.999	0.000
B06 Rubella [German measles]	0.001	0.999	0.000
B05 Measles	0.001	0.999	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.001	0.999	0.000
B04 Monkeypox	0.001	0.999	0.000
B03 Smallpox	0.001	0.999	0.000
F99 Mental disorder, not otherwise specified	0.000	0.999	0.001
B00.1 Herpesviral vesicular dermatitis	0.001	0.999	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.001	0.999	0.000
N11 Chronic tubulo-interstitial nephritis	0.001	0.999	0.000
N26 Unspecified contracted kidney	0.001	0.999	0.000
D43.0 Brain, supratentorial	0.001	0.999	0.000
Y40.5 Aminoglycosides	0.001	0.999	0.000
Z43.8 Attention to other artificial openings	0.001	0.999	0.000
Z43.1 Attention to gastrostomy	0.001	0.999	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.999	0.001
M25.79 Osteophyte (Site unspecified)	0.000	0.999	0.001
M25.73 Osteophyte (Forearm)	0.000	0.999	0.001
M25.70 Osteophyte (Multiple sites)	0.000	0.999	0.001
M67.49 Ganglion, multiple sites	0.000	0.999	0.001
M67.47 Ganglion, ankle and foot	0.000	0.999	0.001
M67.45 Ganglion, hip	0.000	0.999	0.001
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.000	0.999	0.001
D37.5 Rectum	0.001	0.999	0.000
S27.2 Traumatic heamopneumothorax	0.001	0.999	0.000
W19.4 Street and highway	0.001	0.999	0.000
G24.5 Blepharospasm	0.001	0.999	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.001	0.999	0.000
N14.3 Nephropathy induced by heavy metals	0.001	0.999	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.001	0.999	0.000
N14.0 Analgesic nephropathy	0.001	0.999	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.001	0.999	0.000
N15.1 Renal and perinephric abscess	0.001	0.999	0.000
N15.0 Balkan nephropathy	0.001	0.999	0.000
Y40.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
M60.05 Infective myositis (Pelvic region and thigh)	0.001	0.999	0.000
M67.43 Ganglion, wrist	0.000	0.999	0.001
H53.4 Visual field defects	0.001	0.999	0.000
M25.78 Osteophyte (Other)	0.000	0.999	0.001
D10.3 Other and unspecified parts of mouth	0.001	0.999	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.999	0.001
F41.9 Anxiety disorder, unspecified	0.001	0.999	0.000
H26.4 After-cataract	0.001	0.999	0.000
O21.8 Other vomiting complicating pregnancy	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.999	0.001
G24 Dystonia	0.001	0.999	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.001	0.999	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.001	0.999	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.001	0.999	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.001	0.999	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.001	0.999	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.001	0.999	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
G41 Status epilepticus	0.000	0.999	0.001
H66.9 Otitis media, unspecified	0.001	0.999	0.000
S27.0 Traumatic pneumothorax	0.001	0.999	0.000
T93.2 Sequelae of other fractures of lower limb	0.001	0.999	0.000
B01 Varicella [chickenpox]	0.001	0.999	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.000	0.999	0.001
S36.00 Injury of spleen (without open wound into cavity)	0.001	0.999	0.000
B05.9 Measles without complication	0.001	0.999	0.000
B05.8 Measles with other complications	0.001	0.999	0.000
B05.4 Measles with intestinal complications	0.001	0.999	0.000
B05.3 Measles complicated by otitis media	0.001	0.999	0.000
B05.2 Measles complicated by pneumonia	0.001	0.999	0.000
B05.1 Measles complicated by meningitis	0.001	0.999	0.000
B05.0 Measles complicated by encephalitis	0.001	0.999	0.000
B06.9 Rubella without complication	0.001	0.999	0.000
B06.8 Rubella with other complications	0.001	0.999	0.000
B06.0 Rubella with neurological complications	0.001	0.999	0.000
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
N11.8 Other chronic tubulo-interstitial nephritis	0.001	0.999	0.000
N11.1 Chronic obstructive pyelonephritis	0.001	0.999	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.001	0.999	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.999	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.999	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.999	0.001
Q23.3 Congenital mitral insufficiency	0.000	0.999	0.001
Q23.2 Congenital mitral stenosis	0.000	0.999	0.001
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.999	0.000
Y40.3 Macrolides	0.001	0.999	0.000
F03 Unspecified dementia	0.000	0.999	0.001
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
T90.0 Sequelae of superficial injury of head	0.001	0.999	0.000
Z13.1 Special screening examination for diabetes mellitus	0.001	0.999	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
G24.3 Spasmodic torticollis	0.001	0.999	0.000
G58.8 Other specified mononeuropathies	0.000	0.999	0.001
H54.4 Blindness, one eye	0.001	0.999	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.001	0.999	0.001
M25.72 Osteophyte (Upper arm)	0.000	0.999	0.001
D03.4 Melanoma in situ of scalp and neck	0.001	0.999	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.001	0.999	0.000
D04.7 Skin of lower limb, including hip	0.001	0.999	0.000
O36.5 Maternal care for poor foetal growth	0.001	0.999	0.000
Z43.5 Attention to cyctostomy	0.001	0.999	0.000
L25 Unspecified contact dermatitis	0.001	0.999	0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
G24.4 Idiopathic orofacial dystonia	0.001	0.999	0.000
G24.2 Idiopathic nonfamilial dystonia	0.001	0.999	0.000
G24.1 Idiopathic familial dystonia	0.001	0.999	0.000
G24.0 Drug-induced dystonia	0.001	0.999	0.000
G41.8 Other status epilepticus	0.000	0.999	0.001
G41.2 Complex partial status epilepticus	0.000	0.999	0.001
G41.1 Petit mal status epilepticus	0.000	0.999	0.001
G41.0 Grand mal status epilepticus	0.000	0.999	0.001
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.999	0.001
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.999	0.000
W29.9 Unspecified place	0.001	0.999	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.001	0.999	0.000
D03 Melanoma in situ	0.001	0.999	0.000
T93 Sequelae of injuries of lower limb	0.001	0.999	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.999	0.001
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
M24.27 Disorder of ligament (Ankle and foot)	0.001	0.999	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
B01.8 Varicella with other complications	0.001	0.999	0.000
B01.2 Varicella pneumonia	0.001	0.999	0.000
B01.1 Varicella encephalitis	0.001	0.999	0.000
B01.0 Varicella meningitis	0.001	0.999	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.001	0.999	0.000
D41.4 Bladder	0.001	0.999	0.000
G24.8 Other dystonia	0.001	0.999	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.000	0.999	0.001
K70.0 Alcoholic fatty liver	0.000	0.999	0.001
O21.9 Vomiting of pregnancy, unspecified	0.001	0.999	0.000
Q25.1 Coarctation of aorta	0.001	0.999	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.001	0.999	0.000
D04.2 Skin of ear and external auricular canal	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations