TreeWAS – Variant ID: rs12413409

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I10 Essential (primary) hypertension	0.000	0.000	1.000
I20.0 Unstable angina	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.003	0.997
I20.9 Angina pectoris, unspecified	0.000	0.005	0.995
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.006	0.994
I25.2 Old myocardial infarction	0.000	0.007	0.993
I24 Other acute ischaemic heart diseases	0.000	0.045	0.955
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.101	0.899
I21 Acute myocardial infarction	0.000	0.112	0.888
I24.8 Other forms of acute ischaemic heart disease	0.000	0.142	0.858
I22 Subsequent myocardial infarction	0.000	0.142	0.858
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.195	0.805
I21.4 Acute subendocardial myocardial infarction	0.000	0.197	0.803
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.208	0.792
I25.4 Coronary artery aneurysm	0.000	0.236	0.763
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.243	0.757
I25.5 Ischaemic cardiomyopathy	0.000	0.264	0.736
I20.1 Angina pectoris with documented spasm	0.000	0.272	0.728
I25.3 Aneurysm of heart	0.000	0.281	0.719
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.283	0.717
I10-I15 Hypertensive diseases	0.000	0.294	0.706
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.306	0.694
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.313	0.687
I24.1 Dressler's syndrome	0.000	0.315	0.685
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.335	0.665
I23 Certain current complications following acute myocardial infarction	0.000	0.355	0.644
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.360	0.640
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.360	0.640
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.364	0.636
I22.8 Subsequent myocardial infarction of other sites	0.000	0.382	0.618
Chapter IX Diseases of the circulatory system	0.000	0.414	0.586
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.438	0.562
I15 Secondary hypertension	0.000	0.446	0.553
I13 Hypertensive heart and renal disease	0.000	0.494	0.506
I21.9 Acute myocardial infarction, unspecified	0.000	0.520	0.480
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.538	0.462
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.538	0.462
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.538	0.462
I15.1 Hypertension secondary to other renal disorders	0.000	0.556	0.444
I20.8 Other forms of angina pectoris	0.000	0.564	0.436
I11 Hypertensive heart disease	0.000	0.569	0.430
I00-I02 Acute rheumatic fever	0.000	0.579	0.420
I15.9 Seconday hypertension, unspecified	0.000	0.603	0.397
I15.8 Other secondary hypertension	0.000	0.603	0.397
I15.2 Hypertension secondary to endocrine disorders	0.000	0.603	0.397
I15.0 Renovascular hypertension	0.000	0.603	0.397
I23.8 Other current complications following acute myocardial infarction	0.000	0.610	0.390
I12 Hypertensive renal disease	0.000	0.628	0.372
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.637	0.363
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.637	0.363
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.637	0.363
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.637	0.363
I60-I69 Cerebrovascular diseases	0.000	0.696	0.304
I02 Rheumatic chorea	0.000	0.698	0.301
I01 Rheumatic fever with heart involvement	0.000	0.698	0.301
I00 Rheumatic fever without mention of heart involvement	0.000	0.698	0.301
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.712	0.288
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.725	0.275
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.738	0.261
I12.9 Hypertensive renal disease without renal failure	0.000	0.743	0.257
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.751	0.249
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.763	0.237
I62 Other nontraumatic intracranial haemorrhage	0.000	0.765	0.235
K30 Dyspepsia	0.000	0.765	0.235
I69 Sequelae of cerebrovascular disease	0.000	0.768	0.232
I99 Other and unspecified disorders of circulatory system	0.000	0.777	0.223
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.782	0.218
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.783	0.216
I01.8 Other acute rheumatic heart disease	0.000	0.783	0.216
I01.2 Acute rheumatic myocarditis	0.000	0.783	0.216
I01.1 Acute rheumatic endocarditis	0.000	0.783	0.216
I01.0 Acute rheumatic pericarditis	0.000	0.783	0.216
I02.9 Rheumatic chorea without heart involvement	0.000	0.783	0.216
I02.0 Rheumatic chorea with heart involvement	0.000	0.783	0.216
I63 Cerebral infarction	0.000	0.792	0.208
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.792	0.207
I60 Subarachnoid haemorrhage	0.000	0.793	0.207
I65.2 Occlusion and stenosis of carotid artery	0.000	0.798	0.202
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.807	0.192
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.808	0.191
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.818	0.182
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.819	0.181
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.821	0.179
I69.3 Sequelae of cerebral infarction	0.000	0.826	0.174
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.830	0.170
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.830	0.170
I65.1 Occlusion and stenosis of basilar artery	0.000	0.830	0.170
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.830	0.170
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.830	0.170
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.830	0.170
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.831	0.169
I62.1 Nontraumatic extradural haemorrhage	0.000	0.831	0.169
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.834	0.165
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.835	0.165
I67 Other cerebrovascular diseases	0.000	0.835	0.165
I60.8 Other subarachnoid haemorrhage	0.000	0.837	0.163
I05-I09 Chronic rheumatic heart diseases	0.001	0.838	0.162
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.839	0.161
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.840	0.160
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.844	0.156
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.844	0.156
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.844	0.156
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.844	0.156
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.844	0.156
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.844	0.156
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.844	0.156
I63.8 Other cerebral infarction	0.000	0.846	0.154
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.847	0.153
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.847	0.153
I12.0 Hypertensive renal disease with renal failure	0.000	0.847	0.153
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.851	0.149
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.851	0.149
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.851	0.149
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.851	0.149
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.851	0.149
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.851	0.149
I98.0 Cardiovascular syphilis	0.000	0.851	0.149
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.851	0.148
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.851	0.148
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.851	0.148
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.851	0.148
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.851	0.148
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.855	0.145
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.860	0.140
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.861	0.139
I67.1 Cerebral aneurysm, nonruptured	0.000	0.861	0.139
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.862	0.138
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.862	0.138
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.862	0.138
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.868	0.132
I67.2 Cerebral atherosclerosis	0.000	0.870	0.130
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.871	0.129
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.882	0.118
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.882	0.118
I67.5 Moyamoya disease	0.000	0.882	0.118
I67.4 Hypertensive encephalopathy	0.000	0.882	0.118
I67.3 Progressive vascular leukoencephalopathy	0.000	0.882	0.118
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.882	0.118
I09 Other rheumatic heart diseases	0.001	0.883	0.116
I06 Rheumatic aortic valve diseases	0.001	0.883	0.116
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.887	0.113
I68.0 Cerebral amyloid angiopathy	0.000	0.887	0.112
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.893	0.107
I97.0 Postcardiotomy syndrome	0.000	0.893	0.107
I28 Other diseases of pulmonary vessels	0.001	0.894	0.105
I07 Rheumatic tricuspid valve diseases	0.001	0.896	0.104
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.896	0.104
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.916	0.083
I06.8 Other rheumatic aortic valve diseases	0.001	0.916	0.083
I06.2 Rheumatic aortic stenosis with insufficiency	0.001	0.916	0.083
I06.1 Rheumatic aortic insufficiency	0.001	0.916	0.083
I06.0 Rheumatic aortic stenosis	0.001	0.916	0.083
I09.9 Rheumatic heart disease, unspecified	0.001	0.916	0.083
I09.8 Other specified rheumatic heart diseases	0.001	0.916	0.083
I09.2 Chronic rheumatic pericarditis	0.001	0.916	0.083
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.916	0.083
I09.0 Rheumatic myocarditis	0.001	0.916	0.083
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.917	0.083
I97.1 Other functional disturbances following cardiac surgery	0.001	0.917	0.082
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.924	0.075
I28.1 Aneurysm of pulmonary artery	0.001	0.924	0.075
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.924	0.075
I07.9 Tricuspid valve disease, unspecified	0.001	0.925	0.074
I07.8 Other tricuspid valve diseases	0.001	0.925	0.074
I07.2 Tricuspid stenosis with insufficiency	0.001	0.925	0.074
I07.0 Tricuspid stenosis	0.001	0.925	0.074
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.000	0.925	0.075
I27 Other pulmonary heart diseases	0.001	0.927	0.073
I05 Rheumatic mitral valve diseases	0.001	0.928	0.071
I61 Intracerebral haemorrhage	0.002	0.930	0.068
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.931	0.069
I07.1 Tricuspid insufficiency	0.001	0.938	0.062
I67.8 Other specified cerebrovascular diseases	0.000	0.938	0.062
I26 Pulmonary embolism	0.001	0.939	0.060
I28.8 Other specified diseases of pulmonary vessels	0.001	0.940	0.059
I67.9 Cerebrovascular disease, unspecified	0.000	0.944	0.056
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.945	0.055
I77 Other disorders of arteries and arterioles	0.000	0.946	0.054
I27.0 Primary pulmonary hypertension	0.000	0.946	0.054
I27.8 Other specified pulmonary heart diseases	0.001	0.947	0.053
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.947	0.052
I27.1 Kyphoscoliotic heart disease	0.001	0.947	0.052
I05.8 Other mitral valve diseases	0.001	0.948	0.051
I05.1 Rheumatic mitral insufficiency	0.001	0.948	0.051
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.950	0.049
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.950	0.048
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.002	0.951	0.047
I05.9 Mitral valve disease, unspecified	0.001	0.953	0.046
I77.1 Stricture of artery	0.000	0.953	0.047
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.953	0.045
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.954	0.045
I61.8 Other intracerebral haemorrhage	0.002	0.955	0.043
I27.9 Pulmonary heart disease, unspecified	0.001	0.955	0.044
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.955	0.044
I05.2 Mitral stenosis with insufficiency	0.001	0.958	0.041
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.958	0.042
I08 Multiple valve diseases	0.001	0.958	0.041
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.961	0.039
I79.1 Aortitis in diseases classified elsewhere	0.000	0.961	0.039
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.961	0.039
I70 Atherosclerosis	0.000	0.961	0.039
I77.5 Necrosis of artery	0.000	0.961	0.039
I77.4 Coeliac artery compression syndrome	0.000	0.961	0.039
I77.3 Arterial fibromuscular dysplasia	0.000	0.961	0.039
I77.2 Rupture of artery	0.000	0.961	0.039
I77.6 Arteritis, unspecified	0.000	0.961	0.038
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.001	0.963	0.037
I05.0 Mitral stenosis	0.001	0.963	0.036
I71 Aortic aneurysm and dissection	0.000	0.963	0.037
I95 Hypotension	0.000	0.963	0.037
I72 Other aneurysm	0.000	0.963	0.037
I78 Diseases of capillaries	0.000	0.963	0.036
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.964	0.034
K62.0 Anal polyp	0.035	0.965	0.000
R07.4 Chest pain, unspecified	0.000	0.965	0.035
I30-I52 Other forms of heart disease	0.000	0.965	0.035
I50.1 Left ventricular failure	0.000	0.966	0.034
I74 Arterial embolism and thrombosis	0.000	0.966	0.034
I77.8 Other specified disorders of arteries and arterioles	0.000	0.966	0.033
I77.0 Arteriovenous fistula, acquired	0.000	0.966	0.033
I50 Heart failure	0.000	0.967	0.033
K21 Gastro-oesophageal reflux disease	0.000	0.967	0.033
I45 Other conduction disorders	0.000	0.968	0.032
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.969	0.030
I44 Atrioventricular and left bundle-branch block	0.000	0.970	0.030
I63.9 Cerebral infarction, unspecified	0.000	0.970	0.030
I45.1 Other and unspecified right bundle-branch block	0.000	0.970	0.030
I08.9 Multiple valve disease, unspecified	0.001	0.970	0.029
I72.0 Aneurysm of carotid artery	0.000	0.971	0.029
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.971	0.029
I70.9 Generalised and unspecified atherosclerosis	0.000	0.971	0.028
I70.8 Atherosclerosis of other arteries	0.000	0.971	0.028
I44.1 Atrioventricular block, second degree	0.000	0.972	0.028
I74.5 Embolism and thrombosis of iliac artery	0.000	0.972	0.028
I08.8 Other multiple valve diseases	0.001	0.972	0.027
I72.8 Aneurysm of other specified arteries	0.000	0.972	0.027
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.973	0.027
I71.0 Dissection of aorta [any part]	0.000	0.973	0.027
I44.7 Left bundle-branch block, unspecified	0.000	0.973	0.027
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.973	0.027
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.973	0.027
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.973	0.027
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.973	0.027
I70.1 Atherosclerosis of renal artery	0.000	0.973	0.027
I95.8 Other hypotension	0.000	0.973	0.026
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.973	0.026
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.973	0.026
I72.2 Aneurysm of renal artery	0.000	0.973	0.026
I72.1 Aneurysm of artery of upper extremity	0.000	0.973	0.026
I95.0 Idiopathic hypotension	0.000	0.973	0.026
I78.9 Disease of capillaries, unspecified	0.000	0.973	0.026
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.974	0.026
I78.8 Other diseases of capillaries	0.000	0.974	0.026
I70.0 Atherosclerosis of aorta	0.000	0.974	0.025
I36 Nonrheumatic tricuspid valve disorders	0.000	0.975	0.025
I45.6 Preexcitation syndrome	0.000	0.975	0.025
I52 Other heart disorders in diseases classified elsewhere	0.000	0.975	0.025
I48 Atrial fibrillation and flutter	0.000	0.975	0.025
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.975	0.025
I41 Myocarditis in diseases classified elsewhere	0.000	0.975	0.025
I40 Acute myocarditis	0.000	0.975	0.025
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.975	0.025
I32 Pericarditis in diseases classified elsewhere	0.000	0.975	0.025
I45.3 Trifascicular block	0.000	0.975	0.025
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.975	0.025
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.975	0.025
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.975	0.025
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.975	0.025
I37 Pulmonary valve disorders	0.000	0.975	0.025
I45.2 Bifascicular block	0.000	0.975	0.024
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.976	0.024
I72.4 Aneurysm of artery of lower extremity	0.000	0.976	0.024
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.976	0.024
I72.9 Aneurysm of unspecified site	0.000	0.976	0.023
I45.8 Other specified conduction disorders	0.000	0.976	0.024
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.976	0.024
I74.8 Embolism and thrombosis of other arteries	0.000	0.976	0.023
I45.0 Right fascicular block	0.000	0.977	0.023
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.977	0.023
I44.0 Atrioventricular block, first degree	0.000	0.977	0.023
I45.4 Nonspecific intraventricular block	0.000	0.977	0.022
I44.5 Left posterior fascicular block	0.000	0.978	0.022
I44.6 Other and unspecified fascicular block	0.000	0.978	0.022
I46 Cardiac arrest	0.000	0.978	0.022
I50.9 Heart failure, unspecified	0.000	0.978	0.022
I45.9 Conduction disorder, unspecified	0.000	0.978	0.022
I33 Acute and subacute endocarditis	0.000	0.979	0.021
I45.5 Other specified heart block	0.000	0.979	0.021
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.979	0.020
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.979	0.020
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.979	0.020
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.979	0.020
M20.1 Hallux valgus (acquired)	0.021	0.979	0.000
I30 Acute pericarditis	0.000	0.980	0.020
K27 Peptic ulcer, site unspecified	0.000	0.980	0.020
I95.2 Hypotension due to drugs	0.000	0.980	0.019
I44.3 Other and unspecified atrioventricular block	0.000	0.980	0.020
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.980	0.019
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.980	0.020
I27.2 Other secondary pulmonary hypertension	0.002	0.981	0.018
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.981	0.018
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.981	0.019
I78.1 Naevus, nonneoplastic	0.000	0.981	0.019
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.981	0.019
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.981	0.018
I49 Other cardiac arrhythmias	0.000	0.981	0.019
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.981	0.018
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.981	0.018
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.981	0.018
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.981	0.018
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.982	0.018
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.982	0.018
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.982	0.018
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.982	0.018
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.982	0.018
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.982	0.018
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.982	0.018
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.982	0.018
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.982	0.018
I40.9 Acute myocarditis, unspecified	0.000	0.982	0.018
I40.8 Other acute myocarditis	0.000	0.982	0.018
I40.1 Isolated myocarditis	0.000	0.982	0.018
I40.0 Infective myocarditis	0.000	0.982	0.018
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.982	0.018
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.982	0.018
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.982	0.018
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.982	0.018
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.982	0.018
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.982	0.018
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.982	0.018
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.982	0.018
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.982	0.018
I48.4 Atypical atrial flutter	0.000	0.982	0.018
I48.3 Typical atrial flutter	0.000	0.982	0.018
I48.2 Chronic atrial fibrillation	0.000	0.982	0.018
I48.1 Persistent atrial fibrillation	0.000	0.982	0.018
I48.0 Paroxysmal atrial fibrillation	0.000	0.982	0.018
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.982	0.018
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.982	0.018
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.982	0.018
I38 Endocarditis, valve unspecified	0.000	0.982	0.018
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.982	0.018
I37.9 Pulmonary valve disorder, unspecified	0.000	0.982	0.018
I37.8 Other pulmonary valve disorders	0.000	0.982	0.018
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.982	0.018
I37.0 Pulmonary valve stenosis	0.000	0.982	0.018
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.982	0.018
I37.1 Pulmonary valve insufficiency	0.000	0.982	0.017
I44.4 Left anterior fascicular block	0.000	0.982	0.017
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.982	0.017
I35 Nonrheumatic aortic valve disorders	0.000	0.983	0.017
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.983	0.017
K28 Gastrojejunal ulcer	0.000	0.983	0.017
K23 Disorders of oesophagus in diseases classified elsewhere	0.000	0.983	0.017
I49.0 Ventricular fibrillation and flutter	0.000	0.983	0.017
I44.2 Atrioventricular block, complete	0.000	0.983	0.017
I31 Other diseases of pericardium	0.000	0.983	0.017
I42 Cardiomyopathy	0.000	0.983	0.017
I50.0 Congestive heart failure	0.000	0.984	0.016
I72.3 Aneurysm of iliac artery	0.001	0.984	0.015
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.984	0.013
I46.1 Sudden cardiac death, so described	0.000	0.984	0.016
I73 Other peripheral vascular diseases	0.000	0.984	0.016
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.984	0.015
I46.0 Cardiac arrest with successful resuscitation	0.000	0.984	0.016
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.984	0.015
I33.9 Acute endocarditis, unspecified	0.000	0.985	0.015
I30.8 Other forms of acute pericarditis	0.000	0.985	0.014
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.985	0.014
K27.7 Chronic without haemorrhage or perforation	0.000	0.985	0.014
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.985	0.014
K27.5 Chronic or unspecified with perforation	0.000	0.985	0.014
K27.4 Chronic or unspecified with haemorrhage	0.000	0.985	0.014
K27.3 Acute without haemorrhage or perforation	0.000	0.985	0.014
K27.2 Acute with both haemorrhage and perforation	0.000	0.985	0.014
K27.1 Acute with perforation	0.000	0.985	0.014
K27.0 Acute with haemorrhage	0.000	0.985	0.014
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.986	0.014
M25.46 Effusion of joint (Lower leg)	0.014	0.986	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.986	0.014
K26 Duodenal ulcer	0.000	0.986	0.014
I49.2 Junctional premature depolarisation	0.000	0.986	0.013
I42.0 Dilated cardiomyopathy	0.000	0.987	0.013
I49.8 Other specified cardiac arrhythmias	0.000	0.987	0.013
I46.9 Cardiac arrest, unspecified	0.000	0.987	0.013
I30.1 Infective pericarditis	0.000	0.987	0.013
I49.9 Cardiac arrhythmia, unspecified	0.000	0.987	0.013
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.000	0.987	0.012
K23.1 Megaoesophagus in Chagas' disease	0.000	0.987	0.012
K23.0 Tuberculous oesophagitis	0.000	0.987	0.012
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.987	0.012
K28.7 Chronic without haemorrhage or perforation	0.000	0.987	0.012
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.987	0.012
K28.5 Chronic or unspecified with perforation	0.000	0.987	0.012
K28.4 Chronic or unspecified with haemorrhage	0.000	0.987	0.012
K28.3 Acute without haemorrhage or perforation	0.000	0.987	0.012
K28.2 Acute with both haemorrhage and perforation	0.000	0.987	0.012
K28.1 Acute with perforation	0.000	0.987	0.012
K28.0 Acute with haemorrhage	0.000	0.987	0.012
I35.0 Aortic (valve) stenosis	0.000	0.987	0.013
K26.3 Acute without haemorrhage or perforation	0.000	0.988	0.012
I31.8 Other specified diseases of pericardium	0.000	0.988	0.012
I31.2 Haemopericardium, not elsewhere classified	0.000	0.988	0.012
I31.1 Chronic constrictive pericarditis	0.000	0.988	0.012
I31.0 Chronic adhesive pericarditis	0.000	0.988	0.012
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.988	0.012
I42.6 Alcoholic cardiomyopathy	0.000	0.988	0.012
I42.5 Other restrictive cardiomyopathy	0.000	0.988	0.012
I42.4 Endocardial fibroelastosis	0.000	0.988	0.012
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.988	0.012
I49.1 Atrial premature depolarisation	0.000	0.988	0.012
I30.9 Acute pericarditis, unspecified	0.000	0.988	0.012
I49.4 Other and unspecified premature depolarisation	0.000	0.988	0.012
I42.2 Other hypertrophic cardiomyopathy	0.000	0.988	0.012
R07 Pain in throat and chest	0.000	0.988	0.012
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.988	0.011
I35.1 Aortic (valve) insufficiency	0.000	0.988	0.012
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.988	0.011
I33.0 Acute and subacute infective endocarditis	0.000	0.988	0.011
I73.8 Other specified peripheral vascular diseases	0.000	0.989	0.011
F31.9 Bipolar affective disorder, unspecified	0.000	0.989	0.011
K26.5 Chronic or unspecified with perforation	0.000	0.989	0.011
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.010	0.990	0.000
I42.8 Other cardiomyopathies	0.000	0.990	0.010
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.990	0.010
K26.2 Acute with both haemorrhage and perforation	0.000	0.990	0.010
I35.8 Other aortic valve disorders	0.000	0.990	0.010
I49.5 Sick sinus syndrome	0.000	0.990	0.010
I31.9 Disease of pericardium, unspecified	0.000	0.990	0.010
I47 Paroxysmal tachycardia	0.000	0.990	0.010
K26.7 Chronic without haemorrhage or perforation	0.000	0.990	0.010
R07.2 Precordial pain	0.000	0.990	0.010
I08.0 Disorders of both mitral and aortic valves	0.002	0.991	0.008
K26.0 Acute with haemorrhage	0.000	0.991	0.009
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.991	0.009
F31 Bipolar affective disorder	0.000	0.991	0.009
K26.1 Acute with perforation	0.000	0.991	0.009
I49.3 Ventricular premature depolarisation	0.000	0.991	0.009
R07.3 Other chest pain	0.000	0.991	0.009
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.009	0.991	0.000
R07.0 Pain in throat	0.000	0.991	0.009
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.992	0.008
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.992	0.008
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.008	0.992	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.008	0.992	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.992	0.008
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.008	0.992	0.000
I95.1 Orthostatic hypotension	0.000	0.992	0.007
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.992	0.008
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.993	0.007
M65.9 Synovitis and tenosynovitis, unspecified	0.007	0.993	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.993	0.007
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.007	0.993	0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.007	0.993	0.000
F31.8 Other bipolar affective disorders	0.000	0.993	0.007
F31.7 Bipolar affective disorder, currently in remission	0.000	0.993	0.007
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.993	0.007
K26.4 Chronic or unspecified with haemorrhage	0.000	0.993	0.007
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.993	0.007
I42.9 Cardiomyopathy, unspecified	0.000	0.993	0.006
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.993	0.007
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.993	0.006
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.006	0.993	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.994	0.006
M65.4 Radial styloid tenosynovitis [de Quervain]	0.006	0.994	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.006	0.994	0.000
I47.0 Reentry ventricular arrhythmia	0.000	0.994	0.006
H52.1 Myopia	0.006	0.994	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.006	0.994	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.994	0.006
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.006	0.994	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.006	0.994	0.000
I47.2 Ventricular tachycardia	0.000	0.994	0.006
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.994	0.006
M65 Synovitis and tenosynovitis	0.006	0.994	0.000
M25.4 Effusion of joint	0.006	0.994	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.006	0.994	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.006	0.994	0.000
Z88.6 Personal history of allergy to analgesic agent	0.000	0.995	0.005
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.005	0.995	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.005	0.995	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.005	0.995	0.000
R22.1 Localised swelling, mass and lump, neck	0.005	0.995	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.995	0.005
I88 Nonspecific lymphadenitis	0.000	0.995	0.005
R22.0 Localised swelling, mass and lump, head	0.005	0.995	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.995	0.005
Z95.3 Presence of xenogenic heart valve	0.000	0.995	0.005
H52.0 Hypermetropia	0.005	0.995	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations