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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12423247
log Bayes Factor = 0.921356
Chromosome 12   position 96,858,362  (GRCh37) Explore rs12423247 on Ensembl!
Variant rs12423247 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.877 0.123 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.876 0.124 0.000
Chapter VII Diseases of the eye and adnexa
0.869 0.131 0.000
Chapter XIV Diseases of the genitourinary system
0.868 0.132 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.865 0.135 0.000
M20-M25 Other joint disorders
0.848 0.152 0.000
N40-N51 Diseases of male genital organs
0.843 0.157 0.000
M25 Other joint disorders, not elsewhere classified
0.835 0.165 0.000
M05-M14 Inflammatory polyarthropathies
0.823 0.177 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.820 0.180 0.000
M25.5 Pain in joint
0.819 0.181 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.799 0.201 0.000
N50 Other disorders of male genital organs
0.798 0.202 0.000
H30-H36 Disorders of choroid and retina
0.786 0.214 0.000
H55-H59 Other disorders of eye and adnexa
0.780 0.220 0.000
N99-N99 Other disorders of the genitourinary system
0.774 0.226 0.000
N50.8 Other specified disorders of male genital organs
0.766 0.234 0.000
D69 Purpura and other haemorrhagic conditions
0.765 0.235 0.000
M65-M68 Disorders of synovium and tendon
0.765 0.235 0.000
N25-N29 Other disorders of kidney and ureter
0.764 0.236 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.764 0.236 0.000
Chapter VIII Diseases of the ear and mastoid process
0.748 0.252 0.000
D50-D53 Nutritional anaemias
0.740 0.260 0.000
M06 Other rheumatoid arthritis
0.733 0.267 0.000
H35 Other retinal disorders
0.731 0.269 0.000
D69.6 Thrombocytopenia, unspecified
0.731 0.269 0.000
S80-S89 Injuries to the knee and lower leg
0.730 0.270 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.730 0.270 0.000
N42 Other disorders of prostate
0.728 0.272 0.000
N60-N64 Disorders of breast
0.725 0.275 0.000
D80-D89 Certain disorders involving the immune mechanism
0.725 0.275 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.722 0.278 0.000
N43 Hydrocele and spermatocele
0.719 0.281 0.000
Chapter X Diseases of the respiratory system
0.715 0.285 0.000
M70-M79 Other soft tissue disorders
0.715 0.285 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.710 0.290 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.707 0.293 0.000
N00-N08 Glomerular diseases
0.702 0.298 0.000
M65 Synovitis and tenosynovitis
0.701 0.299 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.696 0.304 0.000
M45-M49 Spondylopathies
0.694 0.305 0.000
M91-M94 Chondropathies
0.693 0.307 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.689 0.311 0.000
M25.52 Pain in joint (Upper arm)
0.688 0.312 0.000
D68 Other coagulation defects
0.685 0.315 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.683 0.317 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.683 0.317 0.000
H57 Other disorders of eye and adnexa
0.683 0.317 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.681 0.319 0.000
S20-S29 Injuries to the thorax
0.680 0.320 0.000
H43-H45 Disorders of vitreous body and globe
0.680 0.320 0.000
N30-N39 Other diseases of urinary system
0.675 0.325 0.000
T79-T79 Certain early complications of trauma
0.674 0.326 0.000
N17-N19 Renal failure
0.671 0.329 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.667 0.333 0.000
H60-H62 Diseases of external ear
0.667 0.333 0.000
N60 Benign mammary dysplasia
0.667 0.333 0.000
M21 Other acquired deformities of limbs
0.663 0.337 0.000
N20-N23 Urolithiasis
0.660 0.340 0.000
M13 Other arthritis
0.659 0.341 0.000
M25.8 Other specified joint disorders
0.658 0.342 0.000
M40-M43 Deforming dorsopathies
0.656 0.344 0.000
M25.56 Pain in joint (Lower leg)
0.653 0.347 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.652 0.348 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.652 0.348 0.000
M65.3 Trigger finger
0.647 0.353 0.000
M25.54 Pain in joint (Hand)
0.644 0.356 0.000
M25.53 Pain in joint (Forearm)
0.639 0.361 0.000
M31 Other necrotising vasculopathies
0.637 0.363 0.000
Chapter I Certain infectious and parasitic diseases
0.637 0.363 0.000
J90-J94 Other diseases of pleura
0.636 0.364 0.000
H40-H42 Glaucoma
0.635 0.365 0.000
N42.8 Other specified disorders of prostate
0.633 0.367 0.000
M06.9 Rheumatoid arthritis, unspecified
0.631 0.369 0.000
N43.3 Hydrocele, unspecified
0.629 0.371 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.629 0.371 0.000
Chapter XXII Codes for special purposes
0.628 0.372 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.628 0.372 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.628 0.372 0.000
M60-M63 Disorders of muscles
0.628 0.372 0.000
M00-M03 Infectious arthropathies
0.628 0.372 0.000
H53-H54 Visual disturbances and blindness
0.627 0.372 0.000
M50-M54 Other dorsopathies
0.627 0.373 0.000
O00-O08 Pregnancy with abortive outcome
0.627 0.373 0.000
M10 Gout
0.627 0.373 0.000
M25.4 Effusion of joint
0.626 0.374 0.000
M25.51 Pain in joint (Shoulder region)
0.625 0.375 0.000
M86-M90 Other osteopathies
0.625 0.375 0.000
H25-H28 Disorders of lens
0.624 0.376 0.000
M11 Other crystal arthropathies
0.624 0.376 0.000
H10-H13 Disorders of conjunctiva
0.623 0.377 0.000
D72 Other disorders of white blood cells
0.622 0.378 0.000
D55-D59 Haemolytic anaemias
0.620 0.380 0.000
S82 Fracture of lower leg, including ankle
0.619 0.381 0.000
M24 Other specific joint derangements
0.619 0.381 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.618 0.382 0.000
M05 Seropositive rheumatoid arthritis
0.614 0.386 0.000
D52 Folate deficiency anaemia
0.614 0.386 0.000
H00 Hordeolum and chalazion
0.613 0.387 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.613 0.387 0.000
H50 Other strabismus
0.612 0.388 0.000
D75 Other diseases of blood and blood-forming organs
0.612 0.388 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.612 0.388 0.000
M25.7 Osteophyte
0.611 0.389 0.000
M25.57 Pain in joint (Ankle and foot)
0.611 0.389 0.000
N48 Other disorders of penis
0.610 0.390 0.000
M07 Psoriatic and enteropathic arthropathies
0.609 0.391 0.000
S81 Open wound of lower leg
0.609 0.391 0.000
M65.34 Trigger finger-Hand
0.609 0.391 0.000
H55 Nystagmus and other irregular eye movements
0.608 0.392 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.608 0.392 0.000
M34 Systemic sclerosis
0.608 0.392 0.000
M33 Dermatopolymyositis
0.608 0.392 0.000
M32 Systemic lupus erythematosus
0.608 0.392 0.000
M30 Polyarteritis nodosa and related conditions
0.608 0.392 0.000
N30 Cystitis
0.607 0.393 0.000
O60-O75 Complications of labour and delivery
0.605 0.395 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.605 0.395 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.605 0.395 0.000
N46 Male infertility
0.605 0.395 0.000
N44 Torsion of testis
0.605 0.395 0.000
N28.1 Cyst of kidney, acquired
0.603 0.397 0.000
H61 Other disorders of external ear
0.600 0.400 0.000
M35 Other systemic involvement of connective tissue
0.599 0.401 0.000
M25.9 Joint disorder, unspecified
0.599 0.401 0.000
M25.3 Other instability of joint
0.599 0.401 0.000
M25.2 Flail joint
0.599 0.401 0.000
M25.1 Fistula of joint
0.599 0.401 0.000
M25.0 Haemarthrosis
0.599 0.401 0.000
H35.0 Background retinopathy and retinal vascular changes
0.596 0.404 0.000
N02 Recurrent and persistent haematuria
0.596 0.404 0.000
S10-S19 Injuries to the neck
0.595 0.405 0.000
S70-S79 Injuries to the hip and thigh
0.593 0.406 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.592 0.408 0.000
M14 Arthropathies in other diseases classified elsewhere
0.590 0.410 0.000
M12 Other specific arthropathies
0.590 0.410 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.590 0.410 0.000
M08 Juvenile arthritis
0.590 0.410 0.000
M06.4 Inflammatory polyarthropathy
0.590 0.410 0.000
H33 Retinal detachments and breaks
0.589 0.411 0.000
D67 Hereditary factor IX deficiency
0.588 0.412 0.000
D66 Hereditary factor VIII deficiency
0.588 0.412 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.588 0.412 0.000
H35.9 Retinal disorder, unspecified
0.588 0.412 0.000
M25.59 Pain in joint (Site unspecified)
0.587 0.413 0.000
M25.58 Pain in joint (Other)
0.587 0.413 0.000
D60-D64 Aplastic and other anaemias
0.586 0.414 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.584 0.416 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.584 0.416 0.000
H35.7 Separation of retinal layers
0.581 0.418 0.000
J90 Pleural effusion, not elsewhere classified
0.581 0.419 0.000
H34 Retinal vascular occlusions
0.581 0.419 0.000
S50-S59 Injuries to the elbow and forearm
0.581 0.419 0.000
M77 Other enthesopathies
0.580 0.420 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.580 0.420 0.000
Chapter V Mental and behavioural disorders
0.578 0.422 0.000
D51 Vitamin B12 deficiency anaemia
0.576 0.424 0.000
T33-T35 Frostbite
0.573 0.427 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.573 0.427 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.573 0.427 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.573 0.427 0.000
T00-T07 Injuries involving multiple body regions
0.573 0.427 0.000
N62 Hypertrophy of breast
0.573 0.427 0.000
N50.1 Vascular disorders of male genital organs
0.573 0.427 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.573 0.427 0.000
N50.9 Disorder of male genital organs, unspecified
0.572 0.427 0.000
N50.0 Atrophy of testis
0.572 0.427 0.000
M22 Disorders of patella
0.572 0.428 0.000
H35.6 Retinal haemorrhage
0.572 0.428 0.000
H80-H83 Diseases of inner ear
0.570 0.430 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.568 0.432 0.000
H57.8 Other specified disorders of eye and adnexa
0.568 0.432 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.564 0.435 0.000
M75 Shoulder lesions
0.564 0.436 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.563 0.437 0.000
H31 Other disorders of choroid
0.563 0.437 0.000
H30 Chorioretinal inflammation
0.563 0.437 0.000
H00.1 Chalazion
0.563 0.437 0.000
H35.3 Degeneration of macula and posterior pole
0.563 0.437 0.000
M94 Other disorders of cartilage
0.562 0.438 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.562 0.438 0.000
D68.0 Von Willebrand's disease
0.561 0.439 0.000
D72.8 Other specified disorders of white blood cells
0.560 0.440 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.559 0.441 0.000
N28.0 Ischaemia and infarction of kidney
0.559 0.441 0.000
N10-N16 Renal tubulo-interstitial diseases
0.558 0.442 0.000
N60.4 Mammary duct ectasia
0.556 0.444 0.000
H26 Other cataract
0.555 0.445 0.000
H61.0 Perichondritis of external ear
0.553 0.447 0.000
M48 Other spondylopathies
0.552 0.448 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.551 0.449 0.000
N42.9 Disorder of prostate, unspecified
0.551 0.449 0.000
T86 Failure and rejection of transplanted organs and tissues
0.551 0.449 0.000
D50 Iron deficiency anaemia
0.550 0.450 0.000
H46 Optic neuritis
0.550 0.450 0.000
D69.9 Haemorrhagic condition, unspecified
0.549 0.451 0.000
D69.8 Other specified haemorrhagic conditions
0.549 0.451 0.000
D69.5 Secondary thrombocytopenia
0.549 0.451 0.000
D69.4 Other primary thrombocytopenia
0.549 0.451 0.000
D69.2 Other nonthrombocytopenic purpura
0.549 0.451 0.000
D69.1 Qualitative platelet defects
0.549 0.451 0.000
D69.0 Allergic purpura
0.549 0.451 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.549 0.451 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.549 0.451 0.000
M66 Spontaneous rupture of synovium and tendon
0.549 0.451 0.000
J60-J70 Lung diseases due to external agents
0.548 0.451 0.000
S00-S09 Injuries to the head
0.548 0.452 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.547 0.452 0.000
N27 Small kidney of unknown cause
0.547 0.452 0.000
N25 Disorders resulting from impaired renal tubular function
0.547 0.452 0.000
N26 Unspecified contracted kidney
0.547 0.452 0.000
S90-S99 Injuries to the ankle and foot
0.547 0.453 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.546 0.454 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.546 0.454 0.000
M06.0 Seronegative rheumatoid arthritis
0.545 0.455 0.000
H43 Disorders of vitreous body
0.544 0.456 0.000
H35.8 Other specified retinal disorders
0.543 0.457 0.000
N60.1 Diffuse cystic mastopathy
0.543 0.457 0.000
M25.50 Pain in joint (Multiple sites)
0.543 0.457 0.000
S89 Other and unspecified injuries of lower leg
0.542 0.458 0.000
T66-T78 Other and unspecified effects of external causes
0.541 0.459 0.000
N41 Inflammatory diseases of prostate
0.541 0.459 0.000
D86 Sarcoidosis
0.540 0.460 0.000
H50.0 Convergent concomitant strabismus
0.539 0.461 0.000
N19 Unspecified renal failure
0.538 0.462 0.000
N45 Orchitis and epididymitis
0.538 0.462 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.537 0.463 0.000
J95-J99 Other diseases of the respiratory system
0.536 0.463 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.536 0.464 0.000
J09-J18 Influenza and pneumonia
0.534 0.466 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.533 0.467 0.000
D68.9 Coagulation defect, unspecified
0.533 0.467 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.533 0.467 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.532 0.468 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.532 0.468 0.000
M80-M85 Disorders of bone density and structure
0.532 0.468 0.000
B15-B19 Viral hepatitis
0.531 0.469 0.000
S40-S49 Injuries to the shoulder and upper arm
0.531 0.469 0.000
D53 Other nutritional anaemias
0.530 0.469 0.000
M71 Other bursopathies
0.529 0.471 0.000
M72 Fibroblastic disorders
0.528 0.472 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.528 0.472 0.000
S27 Injury of other and unspecified intrathoracic organs
0.527 0.473 0.000
N61 Inflammatory disorders of breast
0.526 0.474 0.000
M06.8 Other specified rheumatoid arthritis
0.526 0.474 0.000
M06.3 Rheumatoid nodule
0.526 0.474 0.000
M06.2 Rheumatoid bursitis
0.526 0.474 0.000
M06.1 Adult-onset Still's disease
0.526 0.474 0.000
O04 Medical abortion
0.525 0.475 0.000
H02 Other disorders of eyelid
0.525 0.475 0.000
N60.2 Fibroadenosis of breast
0.525 0.475 0.000
N30.9 Cystitis, unspecified
0.525 0.475 0.000
H35.5 Hereditary retinal dystrophy
0.524 0.475 0.000
H35.4 Peripheral retinal degeneration
0.524 0.475 0.000
H35.2 Other proliferative retinopathy
0.524 0.475 0.000
H35.1 Retinopathy of prematurity
0.524 0.475 0.000
H52 Disorders of refraction and accommodation
0.524 0.476 0.000
D52.9 Folate deficiency anaemia, unspecified
0.524 0.476 0.000
S88 Traumatic amputation of lower leg
0.523 0.476 0.000
S87 Crushing injury of lower leg
0.523 0.476 0.000
S86 Injury of muscle and tendon at lower leg level
0.523 0.476 0.000
S85 Injury of blood vessels at lower leg level
0.523 0.476 0.000
S84 Injury of nerves at lower leg level
0.523 0.476 0.000
O85-O92 Complications predominantly related to the puerperium
0.523 0.476 0.000
N42.3 Dysplasia of prostate
0.522 0.478 0.000
N42.2 Atrophy of prostate
0.522 0.478 0.000
N42.0 Calculus of prostate
0.522 0.478 0.000
M41 Scoliosis
0.522 0.478 0.000
S81.8 Open wound of other parts of lower leg
0.522 0.478 0.000
N42.1 Congestion and haemorrhage of prostate
0.522 0.478 0.000
H57.1 Ocular pain
0.520 0.479 0.000
N02.9 Unspecified
0.520 0.480 0.000
D84 Other immunodeficiencies
0.519 0.480 0.000
D83 Common variable immunodeficiency
0.519 0.480 0.000
D82 Immunodeficiency associated with other major defects
0.519 0.480 0.000
D81 Combined immunodeficiencies
0.519 0.480 0.000
D80 Immunodeficiency with predominantly antibody defects
0.519 0.480 0.000
M50 Cervical disk disorders
0.519 0.481 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.518 0.481 0.000
N20 Calculus of kidney and ureter
0.518 0.482 0.000
H54 Blindness and low vision
0.518 0.482 0.000
H51 Other disorders of binocular movement
0.517 0.482 0.000
H49 Paralytic strabismus
0.517 0.482 0.000
N48.2 Other inflammatory disorders of penis
0.517 0.483 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.517 0.483 0.000
M21.1 Varus deformity, not elsewhere classified
0.517 0.483 0.000
N60.0 Solitary cyst of breast
0.516 0.484 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.516 0.484 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.516 0.484 0.000
N43.4 Spermatocele
0.515 0.485 0.000
N43.2 Other hydrocele
0.515 0.485 0.000
N43.1 Infected hydrocele
0.515 0.485 0.000
N43.0 Encysted hydrocele
0.515 0.485 0.000
M25.84 Other specified joint disorders (Hand)
0.515 0.485 0.000
M13.9 Arthritis, unspecified
0.513 0.487 0.000
D75.1 Secondary polycythaemia
0.513 0.487 0.000
M76 Enthesopathies of lower limb, excluding foot
0.512 0.488 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.512 0.488 0.000
M47 Spondylosis
0.512 0.488 0.000
H18 Other disorders of cornea
0.511 0.489 0.000
S80 Superficial injury of lower leg
0.510 0.489 0.000
H65-H75 Diseases of middle ear and mastoid
0.510 0.490 0.000
M20 Acquired deformities of fingers and toes
0.509 0.491 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.509 0.491 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.509 0.491 0.000
D74 Methaemoglobinaemia
0.509 0.491 0.000
D73 Diseases of spleen
0.509 0.491 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.509 0.491 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.509 0.491 0.000
M13.0 Polyarthritis, unspecified
0.508 0.492 0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified
0.507 0.493 0.000
N99.5 Malfunction of external stoma of urinary tract
0.507 0.493 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.507 0.493 0.000
N99.2 Postprocedural adhesions of vagina
0.507 0.493 0.000
N99.1 Postprocedural urethral stricture
0.507 0.493 0.000
N99.0 Postprocedural renal failure
0.507 0.493 0.000
S60-S69 Injuries to the wrist and hand
0.506 0.494 0.000
D50.8 Other iron deficiency anaemias
0.505 0.495 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.503 0.496 0.000
N06 Isolated proteinuria with specified morphological lesion
0.503 0.496 0.000
N05 Unspecified nephritic syndrome
0.503 0.496 0.000
N04 Nephrotic syndrome
0.503 0.496 0.000
N01 Rapidly progressive nephritic syndrome
0.503 0.496 0.000
N00 Acute nephritic syndrome
0.503 0.496 0.000
M65.8 Other synovitis and tenosynovitis
0.503 0.497 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.503 0.497 0.000
M65.2 Calcific tendinitis
0.503 0.497 0.000
M65.1 Other infective (teno)synovitis
0.503 0.497 0.000
M65.0 Abscess of tendon sheath
0.503 0.497 0.000
S20 Superficial injury of thorax
0.502 0.497 0.000
H60 Otitis externa
0.502 0.498 0.000
S82.3 Fracture of lower end of tibia
0.502 0.498 0.000
Q60-Q64 Congenital malformations of the urinary system
0.501 0.499 0.000
M21.0 Valgus deformity, not elsewhere classified
0.501 0.499 0.000
O62 Abnormalities of forces of labour
0.501 0.499 0.000
M45 Ankylosing spondylitis
0.501 0.499 0.000
S82.5 Fracture of medial malleolus
0.501 0.499 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.500 0.500 0.000
M23 Internal derangement of knee
0.499 0.501 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.499 0.501 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.499 0.501 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.499 0.501 0.000
T87 Complications peculiar to reattachment and amputation
0.499 0.501 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.499 0.501 0.000
B95-B98 Bacterial, viral and other infectious agents
0.499 0.501 0.000
M67 Other disorders of synovium and tendon
0.499 0.501 0.000
N36 Other disorders of urethra
0.498 0.501 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.498 0.502 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.498 0.502 0.000
M49 Spondylopathies in diseases classified elsewhere
0.498 0.502 0.000
M46 Other inflammatory spondylopathies
0.498 0.502 0.000
M93 Other osteochondropathies
0.497 0.503 0.000
M92 Other juvenile osteochondrosis
0.497 0.503 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.497 0.503 0.000
N40 Hyperplasia of prostate
0.497 0.503 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.494 0.506 0.000
H81 Disorders of vestibular function
0.494 0.506 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.494 0.506 0.000
J92 Pleural plaque
0.493 0.507 0.000
Chapter XX External causes of morbidity and mortality
0.493 0.507 0.000
N21 Calculus of lower urinary tract
0.493 0.507 0.000
M25.86 Other specified joint disorders (Lower leg)
0.493 0.507 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.493 0.507 0.000
H90-H95 Other disorders of ear
0.492 0.508 0.000
O02 Other abnormal products of conception
0.492 0.508 0.000
T79.6 Traumatic ischaemia of muscle
0.491 0.508 0.000
H20 Iridocyclitis
0.491 0.509 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.491 0.509 0.000
D68.8 Other specified coagulation defects
0.491 0.509 0.000
D68.6 Other Thrombophilia
0.491 0.509 0.000
D68.5 Primary Thrombophilia
0.491 0.509 0.000
D68.4 Acquired coagulation factor deficiency
0.491 0.509 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.491 0.509 0.000
D68.2 Hereditary deficiency of other clotting factors
0.491 0.509 0.000
D68.1 Hereditary factor XI deficiency
0.491 0.509 0.000
A80-A89 Viral infections of the central nervous system
0.491 0.509 0.000
D75.2 Essential thrombocytosis
0.490 0.510 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.490 0.510 0.000
H05 Disorders of orbit
0.490 0.510 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.490 0.510 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.490 0.510 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.490 0.510 0.000
H57.0 Anomalies of pupillary function
0.490 0.510 0.000
S82.6 Fracture of lateral malleolus
0.489 0.511 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.488 0.512 0.000
N30.1 Interstitial cystitis (chronic)
0.488 0.512 0.000
M31.3 Wegener's granulomatosis
0.488 0.512 0.000
N17 Acute renal failure
0.488 0.512 0.000
S29 Other and unspecified injuries of thorax
0.488 0.512 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.488 0.512 0.000
S26 Injury of heart
0.488 0.512 0.000
S25 Injury of blood vessels of thorax
0.488 0.512 0.000
S24 Injury of nerves and spinal cord at thorax level
0.488 0.512 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.488 0.512 0.000
S21 Open wound of thorax
0.488 0.512 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.487 0.512 0.000
H44 Disorders of globe
0.487 0.512 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.487 0.512 0.000
M24.2 Disorder of ligament
0.487 0.513 0.000
M10.9 Gout, unspecified
0.486 0.514 0.000
O42 Premature rupture of membranes
0.486 0.514 0.000
N60.8 Other benign mammary dysplasias
0.486 0.514 0.000
N30.0 Acute cystitis
0.486 0.514 0.000
H36 Retinal disorders in diseases classified elsewhere
0.485 0.515 0.000
N28.8 Other specified disorders of kidney and ureter
0.485 0.515 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.485 0.515 0.000
J40-J47 Chronic lower respiratory diseases
0.485 0.515 0.000
M77.1 Lateral epicondylitis
0.484 0.516 0.000
N37 Urethral disorders in diseases classified elsewhere
0.484 0.516 0.000
N34 Urethritis and urethral syndrome
0.484 0.516 0.000
N33 Bladder disorders in diseases classified elsewhere
0.484 0.516 0.000
N03 Chronic nephritic syndrome
0.483 0.516 0.000
H26.4 After-cataract
0.482 0.518 0.000
O72 Postpartum haemorrhage
0.482 0.518 0.000
M11.2 Other chondrocalcinosis
0.481 0.518 0.000
O63 Long labour
0.480 0.520 0.000
B25-B34 Other viral diseases
0.480 0.520 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.479 0.520 0.000
M35.0 Sicca syndrome [Sjogren]
0.478 0.521 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.478 0.522 0.000
H21 Other disorders of iris and ciliary body
0.478 0.522 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.478 0.522 0.000
H17 Corneal scars and opacities
0.478 0.522 0.000
H16 Keratitis
0.478 0.522 0.000
H15 Disorders of sclera
0.478 0.522 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.478 0.522 0.000
N60.9 Benign mammary dysplasia, unspecified
0.478 0.522 0.000
N60.3 Fibrosclerosis of breast
0.478 0.522 0.000
H33.2 Serous retinal detachment
0.478 0.522 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.478 0.522 0.000
J81 Pulmonary oedema
0.476 0.524 0.000
J30-J39 Other diseases of upper respiratory tract
0.476 0.524 0.000
M21.9 Acquired deformity of limb, unspecified
0.475 0.525 0.000
M21.8 Other specified acquired deformities of limbs
0.475 0.525 0.000
M21.7 Unequal limb length (acquired)
0.475 0.525 0.000
M21.6 Other acquired deformities of ankle and foot
0.475 0.525 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.475 0.525 0.000
M21.4 Flat foot [pes planus] (acquired)
0.475 0.525 0.000
M21.2 Flexion deformity
0.475 0.525 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.474 0.526 0.000
H43.8 Other disorders of vitreous body
0.473 0.527 0.000
M13.8 Other specified arthritis
0.472 0.528 0.000
M13.1 Monoarthritis, not elsewhere classified
0.472 0.528 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.472 0.528 0.000
M25.88 Other specified joint disorders (Other)
0.472 0.528 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.472 0.528 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.472 0.528 0.000
M25.83 Other specified joint disorders (Forearm)
0.472 0.528 0.000
M25.82 Other specified joint disorders (Upper arm)
0.472 0.528 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.472 0.528 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.472 0.528 0.000
M42 Spinal osteochondrosis
0.471 0.529 0.000
M40 Kyphosis and lordosis
0.471 0.529 0.000
M25.47 Effusion of joint (Ankle and foot)
0.471 0.529 0.000
H26.9 Cataract, unspecified
0.471 0.529 0.000
S22.3 Fracture of rib
0.470 0.530 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.470 0.530 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.470 0.530 0.000
M94.8 Other specified disorders of cartilage
0.469 0.531 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.469 0.531 0.000
M75.5 Bursitis of shoulder
0.469 0.531 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.468 0.532 0.000
Q80-Q89 Other congenital malformations
0.468 0.532 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.468 0.532 0.000
Q50-Q56 Congenital malformations of genital organs
0.468 0.532 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.468 0.532 0.000
Q35-Q37 Cleft lip and cleft palate
0.468 0.532 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.468 0.532 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.468 0.532 0.000
Q00-Q07 Congenital malformations of the nervous system
0.468 0.532 0.000
S82.2 Fracture of shaft of tibia
0.467 0.533 0.000
H01 Other inflammation of eyelid
0.467 0.533 0.000
T82.1 Mechanical complication of cardiac electronic device
0.467 0.533 0.000
H40 Glaucoma
0.467 0.533 0.000
M86 Osteomyelitis
0.466 0.534 0.000
M21.3 Wrist or foot drop (acquired)
0.466 0.534 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.464 0.536 0.000
M65.39 Trigger finger-Site unspec
0.464 0.536 0.000
M65.38 Trigger finger-Other
0.464 0.536 0.000
M65.37 Trigger finger-Ankle/foot
0.464 0.536 0.000
M65.36 Trigger finger-Lower leg
0.464 0.536 0.000
M65.35 Trigger finger-Pelvic/thigh
0.464 0.536 0.000
M65.33 Trigger finger-Forearm
0.464 0.536 0.000
M65.32 Trigger finger-Upper arm
0.464 0.536 0.000
M65.31 Trigger finger-Shldr region
0.464 0.536 0.000
M65.30 Trigger finger-Mult sites
0.464 0.536 0.000
H50.9 Strabismus, unspecified
0.464 0.536 0.000
N39 Other disorders of urinary system
0.463 0.537 0.000
N48.0 Leukoplakia of penis
0.463 0.537 0.000
N64 Other disorders of breast
0.462 0.537 0.000
N48.8 Other specified disorders of penis
0.461 0.539 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.461 0.539 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.461 0.539 0.000
O80-O84 Delivery
0.460 0.540 0.000
N18 Chronic renal failure
0.460 0.540 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.459 0.541 0.000
J00-J06 Acute upper respiratory infections
0.459 0.541 0.000
J91 Pleural effusion in conditions classified elsewhere
0.459 0.541 0.000
O03 Spontaneous abortion
0.458 0.541 0.000
T85.2 Mechanical complication of intraocular lens
0.458 0.541 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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