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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1243507
log Bayes Factor = 18.6876
Chromosome 14   position 95,314,433  (GRCh37) Explore rs1243507 on Ensembl!
Variant rs1243507 is part of Cluster X0181

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.995 0.005 0.000
J40-J47 Chronic lower respiratory diseases
0.994 0.006 0.000
F30-F39 Mood [affective] disorders
0.991 0.009 0.000
M25 Other joint disorders, not elsewhere classified
0.990 0.010 0.000
M45-M49 Spondylopathies
0.987 0.013 0.000
S50-S59 Injuries to the elbow and forearm
0.987 0.013 0.000
J47 Bronchiectasis
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.984 0.016 0.000
M13 Other arthritis
0.981 0.019 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.974 0.026 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.973 0.027 0.000
J20-J22 Other acute lower respiratory infections
0.967 0.033 0.000
Chapter I Certain infectious and parasitic diseases
0.967 0.033 0.000
M13.9 Arthritis, unspecified
0.964 0.036 0.000
M47 Spondylosis
0.963 0.037 0.000
S52 Fracture of forearm
0.962 0.038 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.952 0.048 0.000
F31 Bipolar affective disorder
0.951 0.049 0.000
Chapter IX Diseases of the circulatory system
0.946 0.054 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.940 0.060 0.000
J44 Other chronic obstructive pulmonary disease
0.938 0.062 0.000
M21 Other acquired deformities of limbs
0.938 0.062 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.937 0.063 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.936 0.064 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.935 0.065 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.934 0.066 0.000
I95 Hypotension
0.931 0.069 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.928 0.072 0.000
M25.5 Pain in joint
0.923 0.077 0.000
S80-S89 Injuries to the knee and lower leg
0.922 0.078 0.000
J22 Unspecified acute lower respiratory infection
0.922 0.078 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.921 0.079 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.918 0.082 0.000
F32 Depressive episode
0.917 0.083 0.000
F31.9 Bipolar affective disorder, unspecified
0.914 0.086 0.000
M47.8 Other spondylosis
0.913 0.087 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.909 0.091 0.000
E00-E07 Disorders of thyroid gland
0.908 0.092 0.000
J95-J99 Other diseases of the respiratory system
0.908 0.092 0.000
M10 Gout
0.908 0.092 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.908 0.092 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.907 0.093 0.000
M06 Other rheumatoid arthritis
0.899 0.101 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.898 0.102 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.898 0.102 0.000
M86-M90 Other osteopathies
0.897 0.103 0.000
M24 Other specific joint derangements
0.895 0.105 0.000
T91 Sequelae of injuries of neck and trunk
0.893 0.107 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.893 0.107 0.000
M23 Internal derangement of knee
0.891 0.109 0.000
Y43 Primarily systemic agents
0.890 0.110 0.000
J60-J70 Lung diseases due to external agents
0.889 0.111 0.000
M47.9 Spondylosis, unspecified
0.887 0.113 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.886 0.114 0.000
S51 Open wound of forearm
0.886 0.114 0.000
I95.9 Hypotension, unspecified
0.884 0.116 0.000
Chapter VII Diseases of the eye and adnexa
0.883 0.117 0.000
M65-M68 Disorders of synovium and tendon
0.882 0.118 0.000
I95.1 Orthostatic hypotension
0.880 0.120 0.000
Chapter VIII Diseases of the ear and mastoid process
0.875 0.125 0.000
B95-B98 Bacterial, viral and other infectious agents
0.874 0.126 0.000
E04 Other non-toxic goitre
0.874 0.126 0.000
S52.6 Fracture of lower end of both ulna and radius
0.874 0.126 0.000
M15-M19 Arthrosis
0.873 0.127 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.872 0.128 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.867 0.133 0.000
A30-A49 Other bacterial diseases
0.866 0.134 0.000
J90-J94 Other diseases of pleura
0.863 0.137 0.000
J98 Other respiratory disorders
0.859 0.141 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.858 0.142 0.000
M45 Ankylosing spondylitis
0.857 0.143 0.000
M31 Other necrotising vasculopathies
0.853 0.147 0.000
M25.4 Effusion of joint
0.852 0.148 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.849 0.151 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.849 0.151 0.000
M17 Gonarthrosis [arthrosis of knee]
0.848 0.152 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.848 0.152 0.000
M10.9 Gout, unspecified
0.845 0.155 0.000
M17.1 Other primary gonarthrosis
0.843 0.157 0.000
X50-X57 Overexertion, travel and privation
0.843 0.157 0.000
F32.0 Mild depressive episode
0.842 0.158 0.000
M21.3 Wrist or foot drop (acquired)
0.841 0.159 0.000
M25.8 Other specified joint disorders
0.840 0.160 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.840 0.160 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.838 0.162 0.000
E06 Thyroiditis
0.837 0.163 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.836 0.164 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.834 0.166 0.000
Y42.7 Androgens and anabolic congeners
0.834 0.166 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.831 0.169 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.831 0.169 0.000
T79-T79 Certain early complications of trauma
0.829 0.171 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.829 0.171 0.000
M25.50 Pain in joint (Multiple sites)
0.827 0.173 0.000
M25.7 Osteophyte
0.826 0.174 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.825 0.174 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.825 0.175 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.824 0.176 0.000
E04.9 Non-toxic goitre, unspecified
0.823 0.177 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.823 0.177 0.000
G82 Paraplegia and tetraplegia
0.822 0.178 0.000
J20 Acute bronchitis
0.821 0.179 0.000
F99-F99 Unspecified mental disorder
0.820 0.180 0.000
T90 Sequelae of injuries of head
0.819 0.181 0.000
G51 Facial nerve disorders
0.818 0.182 0.000
I95.2 Hypotension due to drugs
0.817 0.183 0.000
S52.2 Fracture of shaft of ulna
0.816 0.184 0.000
T93 Sequelae of injuries of lower limb
0.816 0.184 0.000
Y86 Sequelae of other accidents
0.814 0.186 0.000
F33 Recurrent depressive disorder
0.813 0.187 0.000
M13.0 Polyarthritis, unspecified
0.813 0.187 0.000
M91-M94 Chondropathies
0.812 0.188 0.000
M06.9 Rheumatoid arthritis, unspecified
0.812 0.188 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.811 0.189 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.811 0.189 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.811 0.189 0.000
S81 Open wound of lower leg
0.810 0.190 0.000
M21.6 Other acquired deformities of ankle and foot
0.809 0.191 0.000
J92 Pleural plaque
0.809 0.191 0.000
Y52 Agents primarily affecting the cardiovascular system
0.809 0.191 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.808 0.192 0.000
S52.1 Fracture of upper end of radius
0.808 0.192 0.000
S80 Superficial injury of lower leg
0.806 0.194 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.806 0.194 0.000
G83 Other paralytic syndromes
0.804 0.196 0.000
S40-S49 Injuries to the shoulder and upper arm
0.804 0.196 0.000
S86 Injury of muscle and tendon at lower leg level
0.803 0.197 0.000
F43 Reaction to severe stress, and adjustment disorders
0.803 0.197 0.000
X60-X84 Intentional self-harm
0.803 0.197 0.000
M23.8 Other internal derangements of knee
0.801 0.199 0.000
M25.53 Pain in joint (Forearm)
0.799 0.201 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.798 0.202 0.000
S52.0 Fracture of upper end of ulna
0.797 0.203 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.796 0.204 0.000
Y43.4 Immunosuppressive agents
0.796 0.204 0.000
J94 Other pleural conditions
0.795 0.205 0.000
M46 Other inflammatory spondylopathies
0.795 0.205 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.795 0.205 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.792 0.208 0.000
F80-F89 Disorders of psychological development
0.791 0.209 0.000
M25.9 Joint disorder, unspecified
0.791 0.209 0.000
S20-S29 Injuries to the thorax
0.791 0.209 0.000
M65 Synovitis and tenosynovitis
0.790 0.210 0.000
M40-M43 Deforming dorsopathies
0.790 0.210 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.788 0.212 0.000
Y48 Anaesthetics and therapeutic gases
0.788 0.212 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.787 0.213 0.000
M20 Acquired deformities of fingers and toes
0.787 0.213 0.000
H04 Disorders of lachrymal system
0.787 0.213 0.000
E06.3 Autoimmune thyroiditis
0.786 0.214 0.000
I05-I09 Chronic rheumatic heart diseases
0.785 0.215 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.784 0.216 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.784 0.216 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.784 0.216 0.000
S51.9 Open wound of forearm, part unspecified
0.783 0.217 0.000
M47.86 Other spondylosis (Lumbar region)
0.782 0.218 0.000
T00-T07 Injuries involving multiple body regions
0.782 0.218 0.000
Q60-Q64 Congenital malformations of the urinary system
0.781 0.219 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.781 0.219 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.778 0.222 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.777 0.223 0.000
G81 Hemiplegia
0.777 0.223 0.000
M23.3 Other meniscus derangements
0.777 0.223 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.777 0.223 0.000
F34 Persistent mood [affective] disorders
0.776 0.224 0.000
Y57 Other and unspecified drugs and medicaments
0.776 0.224 0.000
H65-H75 Diseases of middle ear and mastoid
0.776 0.224 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.775 0.225 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.775 0.225 0.000
E50-E64 Other nutritional deficiencies
0.775 0.225 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.772 0.228 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.772 0.228 0.000
A00-A09 Intestinal infectious diseases
0.772 0.228 0.000
M10.99 Gout, unspecified (Site unspecified)
0.771 0.229 0.000
M47.89 Other spondylosis (Site unspecified)
0.770 0.230 0.000
J43 Emphysema
0.769 0.231 0.000
M33 Dermatopolymyositis
0.767 0.232 0.000
E40-E46 Malnutrition
0.767 0.233 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.767 0.233 0.000
H02 Other disorders of eyelid
0.766 0.234 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.765 0.235 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.763 0.237 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.762 0.238 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.762 0.238 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.761 0.238 0.000
M00-M03 Infectious arthropathies
0.761 0.239 0.000
M24.1 Other articular cartilage disorders
0.760 0.240 0.000
V40-V49 Car occupant injured in transport accident
0.758 0.242 0.000
Y40 Systemic antibiotics
0.757 0.243 0.000
S52.8 Fracture of other parts of forearm
0.757 0.243 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.756 0.243 0.000
T98 Sequelae of other and unspecified effects of external causes
0.752 0.248 0.000
V20-V29 Motorcycle rider injured in transport accident
0.750 0.250 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.750 0.250 0.000
A40 Streptococcal septicaemia
0.749 0.251 0.000
Q50-Q56 Congenital malformations of genital organs
0.749 0.251 0.000
M25.46 Effusion of joint (Lower leg)
0.749 0.251 0.000
M23.5 Chronic instability of knee
0.749 0.251 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.748 0.252 0.000
B35-B49 Mycoses
0.748 0.252 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.747 0.253 0.000
T86 Failure and rejection of transplanted organs and tissues
0.747 0.253 0.000
M14 Arthropathies in other diseases classified elsewhere
0.746 0.254 0.000
Q80-Q89 Other congenital malformations
0.746 0.254 0.000
Y42.5 Other oestrogens and progestogens
0.745 0.255 0.000
J00-J06 Acute upper respiratory infections
0.744 0.256 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.743 0.257 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.743 0.257 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.743 0.257 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.743 0.257 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.742 0.258 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.742 0.258 0.000
I87 Other disorders of veins
0.742 0.258 0.000
M25.57 Pain in joint (Ankle and foot)
0.741 0.259 0.000
S70-S79 Injuries to the hip and thigh
0.741 0.259 0.000
M86 Osteomyelitis
0.741 0.259 0.000
E04.0 Non-toxic diffuse goitre
0.741 0.259 0.000
M89 Other disorders of bone
0.740 0.260 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.739 0.261 0.000
M60-M63 Disorders of muscles
0.738 0.262 0.000
M22 Disorders of patella
0.737 0.263 0.000
Y84.0 Cardiac catheterisation
0.735 0.265 0.000
T92 Sequelae of injuries of upper limb
0.735 0.265 0.000
M25.58 Pain in joint (Other)
0.734 0.266 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.734 0.266 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.734 0.266 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.733 0.267 0.000
F42 Obsessive-compulsive disorder
0.732 0.268 0.000
H02.3 Blepharochalasis
0.731 0.269 0.000
T39.1 4-Aminophenol derivatives
0.731 0.269 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.730 0.270 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.729 0.271 0.000
M31.6 Other giant cell arteritis
0.729 0.271 0.000
M06.3 Rheumatoid nodule
0.728 0.272 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.727 0.273 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.725 0.274 0.000
J94.8 Other specified pleural conditions
0.725 0.275 0.000
W00-W19 Falls
0.725 0.275 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.725 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.724 0.276 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.724 0.276 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.723 0.277 0.000
F60-F69 Disorders of adult personality and behaviour
0.722 0.278 0.000
J92.9 Pleural plaque without asbestos
0.721 0.279 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.718 0.282 0.000
S51.0 Open wound of elbow
0.717 0.283 0.000
J20.9 Acute bronchitis, unspecified
0.717 0.283 0.000
M21.2 Flexion deformity
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
S52.7 Multiple fractures of forearm
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.716 0.284 0.000
Y59 Other and unspecified vaccines and biological substances
0.715 0.284 0.000
Y58 Bacterial vaccines
0.715 0.284 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.715 0.284 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.284 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.715 0.284 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.715 0.284 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.715 0.284 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.715 0.284 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.715 0.285 0.000
T91.3 Sequelae of injury of spinal cord
0.715 0.285 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.713 0.287 0.000
J41 Simple and mucopurulent chronic bronchitis
0.713 0.287 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.713 0.287 0.000
M21.4 Flat foot [pes planus] (acquired)
0.712 0.288 0.000
S52.20 Fracture of shaft of ulna (closed)
0.712 0.288 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.711 0.288 0.000
F38 Other mood [affective] disorders
0.711 0.289 0.000
F30 Manic episode
0.711 0.289 0.000
F39 Unspecified mood [affective] disorder
0.711 0.289 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.710 0.290 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.710 0.290 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.710 0.290 0.000
J92.0 Pleural plaque with presence of asbestos
0.710 0.290 0.000
H01 Other inflammation of eyelid
0.710 0.290 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
M25.3 Other instability of joint
0.710 0.290 0.000
M25.2 Flail joint
0.710 0.290 0.000
M25.1 Fistula of joint
0.710 0.290 0.000
M25.0 Haemarthrosis
0.710 0.290 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.708 0.292 0.000
G54 Nerve root and plexus disorders
0.708 0.292 0.000
G61 Inflammatory polyneuropathy
0.708 0.292 0.000
M49 Spondylopathies in diseases classified elsewhere
0.708 0.292 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.708 0.292 0.000
S59 Other and unspecified injuries of forearm
0.707 0.293 0.000
S58 Traumatic amputation of forearm
0.707 0.293 0.000
S57 Crushing injury of forearm
0.707 0.293 0.000
S56 Injury of muscle and tendon at forearm level
0.707 0.293 0.000
S55 Injury of blood vessels at forearm level
0.707 0.293 0.000
S54 Injury of nerves at forearm level
0.707 0.293 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.707 0.293 0.000
S81.9 Open wound of lower leg, part unspecified
0.707 0.293 0.000
M25.84 Other specified joint disorders (Hand)
0.707 0.293 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.707 0.293 0.000
M25.76 Osteophyte (Lower leg)
0.707 0.293 0.000
T87 Complications peculiar to reattachment and amputation
0.705 0.294 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.705 0.295 0.000
M35 Other systemic involvement of connective tissue
0.704 0.296 0.000
T45.0 Antiallergic and antiemetic drugs
0.704 0.296 0.000
M13.8 Other specified arthritis
0.704 0.296 0.000
M13.1 Monoarthritis, not elsewhere classified
0.704 0.296 0.000
G58 Other mononeuropathies
0.703 0.297 0.000
G90-G99 Other disorders of the nervous system
0.703 0.297 0.000
I71 Aortic aneurysm and dissection
0.702 0.298 0.000
T91.1 Sequelae of fracture of spine
0.702 0.298 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.700 0.299 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.700 0.300 0.000
M23.9 Internal derangement of knee, unspecified
0.699 0.301 0.000
T95 Sequelae of burns, corrosions and frostbite
0.699 0.301 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.699 0.301 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.699 0.301 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.699 0.301 0.000
M21.1 Varus deformity, not elsewhere classified
0.698 0.302 0.000
S52.10 Fracture of upper end of radius (closed)
0.698 0.302 0.000
T43.9 Psychotropic drug, unspecified
0.697 0.302 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.697 0.302 0.000
T43.6 Psychostimulants with abuse potential
0.697 0.302 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.697 0.302 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.697 0.302 0.000
M88 Paget's disease of bone [osteitis deformans]
0.697 0.303 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.697 0.303 0.000
Y85 Sequelae of transport accidents
0.696 0.304 0.000
J98.8 Other specified respiratory disorders
0.695 0.305 0.000
A46 Erysipelas
0.695 0.305 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.695 0.305 0.000
S89 Other and unspecified injuries of lower leg
0.694 0.305 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.694 0.306 0.000
M65.3 Trigger finger
0.694 0.306 0.000
F29 Unspecified nonorganic psychosis
0.693 0.307 0.000
J21 Acute bronchiolitis
0.693 0.307 0.000
B99-B99 Other infectious diseases
0.693 0.307 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.693 0.307 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.693 0.307 0.000
B65-B83 Helminthiases
0.693 0.307 0.000
B50-B64 Protozoal diseases
0.693 0.307 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.693 0.307 0.000
A75-A79 Rickettsioses
0.693 0.307 0.000
A70-A74 Other diseases caused by chlamydiae
0.693 0.307 0.000
A65-A69 Other spirochaetal diseases
0.693 0.307 0.000
A20-A28 Certain zoonotic bacterial diseases
0.693 0.307 0.000
A15-A19 Tuberculosis
0.693 0.307 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.692 0.308 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.692 0.308 0.000
F99 Mental disorder, not otherwise specified
0.692 0.308 0.000
Y45.8 Other analgesics and antipyretics
0.692 0.308 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.691 0.309 0.000
M25.42 Effusion of joint (Upper arm)
0.691 0.309 0.000
X50 Overexertion and strenuous or repetitive movements
0.690 0.309 0.000
H55-H59 Other disorders of eye and adnexa
0.690 0.309 0.000
M47.1 Other spondylosis with myelopathy
0.690 0.310 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.690 0.310 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.690 0.310 0.000
S52.9 Fracture of forearm, part unspecified
0.690 0.310 0.000
S52.4 Fracture of shafts of both ulna and radius
0.690 0.310 0.000
S52.3 Fracture of shaft of radius
0.690 0.310 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.690 0.310 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.690 0.310 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.690 0.310 0.000
B15-B19 Viral hepatitis
0.689 0.311 0.000
J98.4 Other disorders of lung
0.689 0.311 0.000
M94 Other disorders of cartilage
0.688 0.311 0.000
S50 Superficial injury of forearm
0.688 0.312 0.000
A48 Other bacterial diseases, not elsewhere classified
0.687 0.313 0.000
M13.93 Arthritis, unspecified (Forearm)
0.686 0.314 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.686 0.314 0.000
J98.6 Disorders of diaphragm
0.686 0.314 0.000
M20.1 Hallux valgus (acquired)
0.686 0.314 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.685 0.315 0.000
A08 Viral and other specified intestinal infections
0.685 0.315 0.000
M17.3 Other posttraumatic gonarthrosis
0.684 0.316 0.000
F80 Specific developmental disorders of speech and language
0.684 0.316 0.000
H90-H95 Other disorders of ear
0.684 0.316 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.683 0.317 0.000
G52 Disorders of other cranial nerves
0.683 0.317 0.000
F31.8 Other bipolar affective disorders
0.682 0.318 0.000
F31.7 Bipolar affective disorder, currently in remission
0.682 0.318 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.682 0.318 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.682 0.318 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.682 0.318 0.000
G51.0 Bell's palsy
0.682 0.318 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.681 0.319 0.000
F43.0 Acute stress reaction
0.681 0.319 0.000
T90.9 Sequelae of unspecified injury of head
0.681 0.319 0.000
S10-S19 Injuries to the neck
0.680 0.320 0.000
G20-G26 Extrapyramidal and movement disorders
0.680 0.320 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.679 0.321 0.000
F43.9 Reaction to severe stress, unspecified
0.679 0.321 0.000
I00-I02 Acute rheumatic fever
0.678 0.321 0.000
J42 Unspecified chronic bronchitis
0.678 0.322 0.000
M25.86 Other specified joint disorders (Lower leg)
0.678 0.322 0.000
F43.2 Adjustment disorders
0.678 0.322 0.000
M80-M85 Disorders of bone density and structure
0.677 0.323 0.000
Y49.2 Other and unspecified antidepressants
0.675 0.325 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.675 0.325 0.000
I27 Other pulmonary heart diseases
0.675 0.325 0.000
I99 Other and unspecified disorders of circulatory system
0.675 0.325 0.000
I87.8 Other specified disorders of veins
0.675 0.325 0.000
V80-V89 Other land transport accidents
0.674 0.326 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.674 0.326 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.673 0.327 0.000
G57 Mononeuropathies of lower limb
0.673 0.327 0.000
M21.9 Acquired deformity of limb, unspecified
0.673 0.327 0.000
M21.8 Other specified acquired deformities of limbs
0.673 0.327 0.000
M21.7 Unequal limb length (acquired)
0.673 0.327 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.673 0.327 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.673 0.327 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.672 0.328 0.000
Y42.9 Other and unspecified hormone antagonists
0.672 0.328 0.000
Y42.4 Oral contraceptives
0.672 0.328 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.672 0.328 0.000
Y42.2 Antithyroid drugs
0.672 0.328 0.000
Y42.1 Thyroid hormones and substitutes
0.672 0.328 0.000
M41 Scoliosis
0.672 0.328 0.000
E04.2 Non-toxic multinodular goitre
0.672 0.328 0.000
J09-J18 Influenza and pneumonia
0.671 0.329 0.000
Y84.6 Urinary catheterisation
0.671 0.329 0.000
I08 Multiple valve diseases
0.671 0.329 0.000
J69 Pneumonitis due to solids and liquids
0.670 0.330 0.000
Y44 Agents primarily affecting blood constituents
0.670 0.330 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.669 0.331 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.669 0.331 0.000
M11 Other crystal arthropathies
0.668 0.332 0.000
E10-E14 Diabetes mellitus
0.668 0.332 0.000
M66 Spontaneous rupture of synovium and tendon
0.668 0.332 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.667 0.332 0.000
I95.8 Other hypotension
0.667 0.332 0.000
I95.0 Idiopathic hypotension
0.667 0.332 0.000
G83.2 Monoplegia of upper limb
0.667 0.333 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.667 0.333 0.000
M34 Systemic sclerosis
0.666 0.333 0.000
A41 Other septicaemia
0.667 0.333 0.000
M13.98 Arthritis, unspecified (Other)
0.666 0.334 0.000
X51 Travel and motion
0.666 0.334 0.000
M90 Osteopathies in diseases classified elsewhere
0.665 0.335 0.000
Y43.3 Other antineoplastic drugs
0.665 0.335 0.000
F32.1 Moderate depressive episode
0.665 0.335 0.000
J02 Acute pharyngitis
0.665 0.335 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.664 0.336 0.000
G53.0 Postzoster neuralgia
0.664 0.336 0.000
S52.00 Fracture of upper end of ulna (closed)
0.664 0.336 0.000
M24.2 Disorder of ligament
0.664 0.336 0.000
G81.9 Hemiplegia, unspecified
0.664 0.336 0.000
S41 Open wound of shoulder and upper arm
0.663 0.337 0.000
F25 Schizoaffective disorders
0.663 0.337 0.000
Q63 Other congenital malformations of kidney
0.663 0.337 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.662 0.338 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.662 0.338 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.662 0.338 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.662 0.338 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.661 0.339 0.000
S88 Traumatic amputation of lower leg
0.661 0.339 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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