TreeWAS – Variant ID: rs12460850

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000
Chapter IX Diseases of the circulatory system	0.998	0.002
I70-I79 Diseases of arteries, arterioles and capillaries	0.997	0.003
Chapter XXI Factors influencing health status and contact with health services	0.996	0.004
I73 Other peripheral vascular diseases	0.995	0.005
M20-M25 Other joint disorders	0.994	0.006
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.993	0.007
Chapter VII Diseases of the eye and adnexa	0.992	0.008
I73.0 Raynaud's syndrome	0.991	0.009
Chapter XV Pregnancy, childbirth and the puerperium	0.989	0.011
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.988	0.012
Chapter I Certain infectious and parasitic diseases	0.988	0.012
H40-H42 Glaucoma	0.985	0.015
H40 Glaucoma	0.980	0.020
Chapter XX External causes of morbidity and mortality	0.976	0.024
Z33 Pregnant state, incidental	0.970	0.030
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.963	0.037
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.961	0.039
H40.9 Glaucoma, unspecified	0.959	0.041
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.958	0.042
I30-I52 Other forms of heart disease	0.955	0.045
A30-A49 Other bacterial diseases	0.945	0.055
Z35 Supervision of high-risk pregnancy	0.943	0.057
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.935	0.065
I73.9 Peripheral vascular disease, unspecified	0.923	0.077
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.923	0.077
Z00-Z13 Persons encountering health services for examination and investigation	0.908	0.092
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.908	0.092
A49 Bacterial infection of unspecified site	0.905	0.095
M25 Other joint disorders, not elsewhere classified	0.900	0.100
H18 Other disorders of cornea	0.899	0.101
Z02 Examination and encounter for administrative purposes	0.894	0.106
Z36 Antenatal screening	0.887	0.113
I49 Other cardiac arrhythmias	0.886	0.114
M31 Other necrotising vasculopathies	0.885	0.115
Z02.8 Other examinations for administrative purposes	0.884	0.116
I77 Other disorders of arteries and arterioles	0.884	0.116
M34 Systemic sclerosis	0.883	0.117
A49.0 Staphylococcal infection, unspecified	0.883	0.117
M25.7 Osteophyte	0.882	0.118
M35 Other systemic involvement of connective tissue	0.881	0.119
I38 Endocarditis, valve unspecified	0.881	0.119
Y42.7 Androgens and anabolic congeners	0.880	0.120
I34 Nonrheumatic mitral valve disorders	0.879	0.121
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.876	0.124
M00-M03 Infectious arthropathies	0.875	0.125
I51 Complications and ill-defined descriptions of heart disease	0.872	0.128
Z39 Postpartum care and examination	0.869	0.131
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.869	0.131
O20-O29 Other maternal disorders predominantly related to pregnancy	0.868	0.132
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.867	0.133
T15-T19 Effects of foreign body entering through natural orifice	0.864	0.136
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.863	0.137
Y40 Systemic antibiotics	0.862	0.138
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.853	0.147
M06.0 Seronegative rheumatoid arthritis	0.850	0.150
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.849	0.151
M21 Other acquired deformities of limbs	0.849	0.151
H46-H48 Disorders of optic nerve and visual pathways	0.845	0.155
M25.76 Osteophyte (Lower leg)	0.844	0.156
I34.0 Mitral (valve) insufficiency	0.843	0.157
I74 Arterial embolism and thrombosis	0.838	0.162
I77.1 Stricture of artery	0.837	0.163
I05-I09 Chronic rheumatic heart diseases	0.837	0.163
I49.0 Ventricular fibrillation and flutter	0.836	0.164
I47 Paroxysmal tachycardia	0.836	0.164
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.836	0.164
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.835	0.165
H40.5 Glaucoma secondary to other eye disorders	0.833	0.167
I30 Acute pericarditis	0.833	0.167
B15-B19 Viral hepatitis	0.833	0.167
O36 Maternal care for other known or suspected foetal problems	0.832	0.168
H30-H36 Disorders of choroid and retina	0.826	0.174
I51.7 Cardiomegaly	0.826	0.174
I72 Other aneurysm	0.825	0.175
O60-O75 Complications of labour and delivery	0.824	0.176
O80-O84 Delivery	0.821	0.179
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.820	0.180
O47 False labour	0.819	0.181
M20 Acquired deformities of fingers and toes	0.814	0.186
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.813	0.187
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.812	0.188
S00-S09 Injuries to the head	0.810	0.190
M24 Other specific joint derangements	0.810	0.190
Y53 Agents primarily affecting the gastro-intestinal system	0.808	0.192
H40.2 Primary angle-closure glaucoma	0.808	0.192
M06.3 Rheumatoid nodule	0.807	0.192
O44 Placenta praevia	0.807	0.193
T36-T50 Poisoning by drugs, medicaments and biological substances	0.805	0.195
H20 Iridocyclitis	0.803	0.197
M20.5 Other deformities of toe(s) (acquired)	0.803	0.197
H40.4 Glaucoma secondary to eye inflammation	0.797	0.203
W00-W19 Falls	0.797	0.203
M25.78 Osteophyte (Other)	0.796	0.204
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.795	0.205
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.795	0.205
M91-M94 Chondropathies	0.794	0.206
O26 Maternal care for other conditions predominantly related to pregnancy	0.793	0.207
Chapter VI Diseases of the nervous system	0.793	0.207
T17 Foreign body in respiratory tract	0.791	0.209
W20-W49 Exposure to inanimate mechanical forces	0.790	0.210
M60-M63 Disorders of muscles	0.790	0.210
Z35.0 Supervision of pregnancy with history of infertility	0.790	0.210
B99-B99 Other infectious diseases	0.787	0.213
M40-M43 Deforming dorsopathies	0.786	0.214
S60-S69 Injuries to the wrist and hand	0.786	0.214
M00 Pyogenic arthritis	0.785	0.215
Z35.8 Supervision of other high-risk pregnancies	0.785	0.215
M34.9 Systemic sclerosis, unspecified	0.784	0.216
M86-M90 Other osteopathies	0.784	0.216
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.783	0.217
S00 Superficial injury of head	0.782	0.218
B35-B49 Mycoses	0.780	0.220
Z63 Other problems related to primary support group, including family circumstances	0.779	0.221
Z39.2 Routine postpartum follow-up	0.779	0.221
M07 Psoriatic and enteropathic arthropathies	0.779	0.221
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.778	0.222
H34 Retinal vascular occlusions	0.777	0.223
B90-B94 Sequelae of infectious and parasitic diseases	0.775	0.225
V10-V19 Pedal cyclist injured in transport accident	0.774	0.226
S40-S49 Injuries to the shoulder and upper arm	0.771	0.229
Z36.2 Other antenatal screening based on amniocentesis	0.769	0.231
Z01.8 Other specified special examinations	0.766	0.234
S70-S79 Injuries to the hip and thigh	0.764	0.236
M11 Other crystal arthropathies	0.763	0.236
Z37 Outcome of delivery	0.763	0.237
H21 Other disorders of iris and ciliary body	0.762	0.238
Q60-Q64 Congenital malformations of the urinary system	0.762	0.238
Y48 Anaesthetics and therapeutic gases	0.761	0.239
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.761	0.239
H18.6 Keratoconus	0.760	0.240
H53-H54 Visual disturbances and blindness	0.756	0.244
H40.8 Other glaucoma	0.755	0.244
Y40.0 Penicillins	0.755	0.245
W50-W64 Exposure to animate mechanical forces	0.754	0.246
B25-B34 Other viral diseases	0.753	0.247
O85-O92 Complications predominantly related to the puerperium	0.753	0.247
Z08 Follow-up examination after treatment for malignant neoplasm	0.753	0.247
Y42.0 Glucocorticoids and synthetic analogs	0.749	0.251
Z35.1 Supervision of pregnancy with history of abortive outcome	0.748	0.252
M65-M68 Disorders of synovium and tendon	0.748	0.252
M06.4 Inflammatory polyarthropathy	0.748	0.252
M35.0 Sicca syndrome [Sjogren]	0.748	0.252
I47.1 Supraventricular tachycardia	0.746	0.254
I30.9 Acute pericarditis, unspecified	0.746	0.254
Y49 Psychotropic drugs, not elsewhere classified	0.745	0.255
O42 Premature rupture of membranes	0.745	0.255
H18.4 Corneal degeneration	0.745	0.255
Z34 Supervision of normal pregnancy	0.741	0.259
Z36.0 Antenatal screening for chromosomal anomalies	0.739	0.261
M31.3 Wegener's granulomatosis	0.738	0.262
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.737	0.263
I10-I15 Hypertensive diseases	0.736	0.263
O24 Diabetes mellitus in pregnancy	0.736	0.264
H47 Other disorders of optic [2nd] nerve and visual pathways	0.735	0.265
H40.0 Glaucoma suspect	0.731	0.268
O44.1 Placenta praevia with haemorrhage	0.730	0.270
Z36.1 Antenatal screening for raised alphafetoprotein level	0.728	0.272
I08 Multiple valve diseases	0.727	0.273
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.726	0.274
S10-S19 Injuries to the neck	0.726	0.274
A00-A09 Intestinal infectious diseases	0.726	0.274
H55-H59 Other disorders of eye and adnexa	0.724	0.276
M14 Arthropathies in other diseases classified elsewhere	0.723	0.277
H18.5 Hereditary corneal dystrophies	0.722	0.278
M35.3 Polymyalgia rheumatica	0.722	0.278
H18.2 Other corneal oedema	0.721	0.279
M00.9 Pyogenic arthritis, unspecified	0.721	0.279
T17.2 Foreign body in pharynx	0.720	0.280
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.718	0.282
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.718	0.282
A80-A89 Viral infections of the central nervous system	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M21.2 Flexion deformity	0.717	0.283
M06.8 Other specified rheumatoid arthritis	0.717	0.283
M06.2 Rheumatoid bursitis	0.717	0.283
M06.1 Adult-onset Still's disease	0.717	0.283
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.717	0.283
M12 Other specific arthropathies	0.717	0.283
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283
M08 Juvenile arthritis	0.717	0.283
V40-V49 Car occupant injured in transport accident	0.717	0.283
I00-I02 Acute rheumatic fever	0.716	0.284
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.715	0.285
O36.9 Maternal care for foetal problem, unspecified	0.714	0.286
G50-G59 Nerve, nerve root and plexus disorders	0.714	0.286
I73.8 Other specified peripheral vascular diseases	0.713	0.286
I73.1 Thromboangiitis obliterans [Buerger]	0.713	0.286
I33 Acute and subacute endocarditis	0.713	0.287
G70-G73 Diseases of myoneural junction and muscle	0.713	0.287
A50-A64 Infections with a predominantly sexual mode of transmission	0.712	0.287
H34.8 Other retinal vascular occlusions	0.712	0.287
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.712	0.288
M33 Dermatopolymyositis	0.712	0.288
M32 Systemic lupus erythematosus	0.712	0.288
M30 Polyarteritis nodosa and related conditions	0.712	0.288
Z38 Liveborn infants according to place of birth	0.712	0.288
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.712	0.288
O47.9 False labour, unspecified	0.711	0.289
M25.74 Osteophyte (Hand)	0.710	0.290
Z01.5 Diagnostic skin and sensitisation tests	0.709	0.290
B85-B89 Pediculosis, acariasis and other infestations	0.708	0.292
B65-B83 Helminthiases	0.708	0.292
B50-B64 Protozoal diseases	0.708	0.292
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.708	0.292
A75-A79 Rickettsioses	0.708	0.292
A70-A74 Other diseases caused by chlamydiae	0.708	0.292
A65-A69 Other spirochaetal diseases	0.708	0.292
A20-A28 Certain zoonotic bacterial diseases	0.708	0.292
A15-A19 Tuberculosis	0.708	0.292
I49.5 Sick sinus syndrome	0.708	0.292
O75 Other complications of labour and delivery, not elsewhere classified	0.708	0.292
B20-B24 Human immunodeficiency virus [HIV] disease	0.708	0.292
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.707	0.293
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.707	0.293
A46 Erysipelas	0.707	0.293
H42 Glaucoma in diseases classified elsewhere	0.706	0.293
H40.6 Glaucoma secondary to drugs	0.703	0.297
H40.3 Glaucoma secondary to eye trauma	0.703	0.297
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.703	0.297
A40 Streptococcal septicaemia	0.703	0.297
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.703	0.297
O26.9 Pregnancy-related condition, unspecified	0.701	0.299
Z39.1 Care and examination of lactating mother	0.700	0.299
S00.0 Superficial injury of scalp	0.700	0.300
Y35-Y36 Legal intervention and operations of war	0.700	0.300
Y10-Y34 Event of undetermined intent	0.700	0.300
Y00-Y09 Assault	0.700	0.300
X85-X99 Assault	0.700	0.300
X58-X59 Accidental exposure to other and unspecified factors	0.700	0.300
X50-X57 Overexertion, travel and privation	0.700	0.300
X30-X39 Exposure to forces of nature	0.700	0.300
X10-X19 Contact with heat and hot substances	0.700	0.300
X00-X09 Exposure to smoke, fire and flames	0.700	0.300
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.700	0.300
W75-W84 Other accidental threats to breathing	0.700	0.300
W65-W74 Accidental drowning and submersion	0.700	0.300
V98-V99 Other and unspecified transport accidents	0.700	0.300
V95-V97 Air and space transport accidents	0.700	0.300
V90-V94 Water transport accidents	0.700	0.300
V70-V79 Bus occupant injured in transport accident	0.700	0.300
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.700	0.300
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.700	0.300
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.700	0.300
V01-V09 Pedestrian injured in transport accident	0.700	0.300
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.698	0.301
O82 Single delivery by Caesarean section	0.698	0.302
Y53.4 Other laxatives	0.697	0.303
Chapter VIII Diseases of the ear and mastoid process	0.697	0.303
S00.8 Superficial injury of other parts of head	0.694	0.305
T18 Foreign body in alimentary tract	0.693	0.307
I49.9 Cardiac arrhythmia, unspecified	0.692	0.308
A41 Other septicaemia	0.692	0.308
Y44 Agents primarily affecting blood constituents	0.691	0.309
Y59 Other and unspecified vaccines and biological substances	0.691	0.309
Y58 Bacterial vaccines	0.691	0.309
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.691	0.309
Y50 Central nervous system stimulants, not elsewhere classified	0.691	0.309
Y47 Sedatives, hypnotics and antianxiety drugs	0.691	0.309
Y46 Antiepileptics and anti-Parkinsonism drugs	0.691	0.309
S06 Intracranial injury	0.691	0.309
H40.1 Primary open-angle glaucoma	0.690	0.310
M25.75 Osteophyte (Pelvic region and thigh)	0.690	0.310
H17 Corneal scars and opacities	0.690	0.310
O94-O99 Other obstetric conditions, not elsewhere classified	0.688	0.311
M31.6 Other giant cell arteritis	0.688	0.312
Chapter XXII Codes for special purposes	0.688	0.312
W44 Foreign body entering into or through eye or natural orifice	0.688	0.312
O36.3 Maternal care for signs of foetal hypoxia	0.688	0.312
O66 Other obstructed labour	0.687	0.312
M80-M85 Disorders of bone density and structure	0.687	0.313
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.687	0.313
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.687	0.313
H15 Disorders of sclera	0.687	0.313
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.687	0.313
Z63.8 Other specified problems related to primary support group	0.686	0.314
O36.0 Maternal care for rhesus isoimmunisation	0.686	0.314
S62 Fracture at wrist and hand level	0.686	0.314
B95-B98 Bacterial, viral and other infectious agents	0.685	0.315
I52 Other heart disorders in diseases classified elsewhere	0.685	0.315
I48 Atrial fibrillation and flutter	0.685	0.315
I43 Cardiomyopathy in diseases classified elsewhere	0.685	0.315
I41 Myocarditis in diseases classified elsewhere	0.685	0.315
I40 Acute myocarditis	0.685	0.315
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.685	0.315
I32 Pericarditis in diseases classified elsewhere	0.685	0.315
S66 Injury of muscle and tendon at wrist and hand level	0.684	0.316
T90 Sequelae of injuries of head	0.684	0.316
V20-V29 Motorcycle rider injured in transport accident	0.684	0.316
H16 Keratitis	0.682	0.318
I12 Hypertensive renal disease	0.682	0.318
Z70-Z76 Persons encountering health services in other circumstances	0.681	0.319
M34.1 CR(E)ST syndrome	0.681	0.319
B16 Acute hepatitis B	0.681	0.319
Z01.4 Gynaecological examination (general)(routine)	0.681	0.319
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.680	0.320
M25.0 Haemarthrosis	0.679	0.321
H20.9 Iridocyclitis, unspecified	0.679	0.321
Y40.8 Other systemic antibiotics	0.679	0.321
A48 Other bacterial diseases, not elsewhere classified	0.678	0.322
A44 Bartonellosis	0.678	0.322
A43 Nocardiosis	0.678	0.322
A42 Actinomycosis	0.678	0.322
A39 Meningococcal infection	0.678	0.322
A37 Whooping cough	0.678	0.322
A36 Diphtheria	0.678	0.322
A32 Listeriosis	0.678	0.322
A31 Infection due to other mycobacteria	0.678	0.322
A30 Leprosy [Hansen's disease]	0.678	0.322
A38 Scarlet fever	0.678	0.322
A35 Other tetanus	0.678	0.322
A34 Obstetrical tetanus	0.678	0.322
A33 Tetanus neonatorum	0.678	0.322
I08.1 Disorders of both mitral and tricuspid valves	0.677	0.323
Q63 Other congenital malformations of kidney	0.676	0.324
G30-G32 Other degenerative diseases of the nervous system	0.676	0.324
Z35.9 Supervision of high-risk pregnancy, unspecified	0.676	0.324
Z35.7 Supervision of high-risk pregnancy due to social problems	0.676	0.324
Z35.6 Supervision of very young primigravida	0.676	0.324
Z35.4 Supervision of pregnancy with grand multiparity	0.676	0.324
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.676	0.324
G20-G26 Extrapyramidal and movement disorders	0.676	0.324
Y42.5 Other oestrogens and progestogens	0.674	0.326
G50 Disorders of trigeminal nerve	0.674	0.326
I49.3 Ventricular premature depolarisation	0.672	0.328
T92 Sequelae of injuries of upper limb	0.672	0.328
I51.4 Myocarditis, unspecified	0.672	0.328
I47.0 Reentry ventricular arrhythmia	0.671	0.329
T33-T35 Frostbite	0.670	0.330
T26-T28 Burns and corrosions confined to eye and internal organs	0.670	0.330
T20-T25 Burns and corrosions of external body surface, specified by site	0.670	0.330
T00-T07 Injuries involving multiple body regions	0.670	0.330
Z36.8 Other antenatal screening	0.670	0.330
M06.34 Rheumatoid nodule (Hand)	0.670	0.330
M89 Other disorders of bone	0.669	0.331
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.668	0.332
O42.9 Premature rupture of membranes, unspecified	0.668	0.332
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.668	0.332
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.667	0.332
I72.4 Aneurysm of artery of lower extremity	0.667	0.333
V80-V89 Other land transport accidents	0.667	0.333
M93 Other osteochondropathies	0.667	0.333
M13 Other arthritis	0.666	0.334
X40-X49 Accidental poisoning by and exposure to noxious substances	0.666	0.334
O47.0 False labour before 37 completed weeks of gestation	0.666	0.334
Y51 Drugs primarily affecting the autonomic nervous system	0.665	0.335
M24.8 Other specific joint derangements, not elsewhere classified	0.664	0.336
I37 Pulmonary valve disorders	0.664	0.336
Z32 Pregnancy examination and test	0.664	0.336
X20-X29 Contact with venomous animals and plants	0.663	0.337
Q80-Q89 Other congenital malformations	0.662	0.338
H35 Other retinal disorders	0.662	0.338
Y42.9 Other and unspecified hormone antagonists	0.661	0.338
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.661	0.338
Y42.4 Oral contraceptives	0.661	0.338
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.661	0.338
Y42.2 Antithyroid drugs	0.661	0.338
Y42.1 Thyroid hormones and substitutes	0.661	0.338
I77.0 Arteriovenous fistula, acquired	0.659	0.341
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.658	0.341
A49.9 Bacterial infection, unspecified	0.658	0.342
H34.2 Other retinal artery occlusions	0.658	0.342
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.656	0.344
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.654	0.346
Z22 Carrier of infectious disease	0.654	0.346
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.653	0.347
O36.4 Maternal care for intra-uterine death	0.653	0.347
O69 Labour and delivery complicated by umbilical cord complications	0.653	0.347
Z10 Routine general health check-up of defined subpopulation	0.651	0.349
O45 Premature separation of placenta [abruptio placentae]	0.651	0.349
O33 Maternal care for known or suspected disproportion	0.651	0.349
O31 Complications specific to multiple gestation	0.651	0.349
M21.0 Valgus deformity, not elsewhere classified	0.651	0.349
Q50-Q56 Congenital malformations of genital organs	0.650	0.349
Z57 Occupational exposure to risk-factors	0.650	0.350
A49.3 Mycoplasma infection, unspecified	0.649	0.351
A49.2 Haemophilus influenzae infection, unspecified	0.649	0.351
M25.3 Other instability of joint	0.649	0.351
I60-I69 Cerebrovascular diseases	0.648	0.352
S68 Traumatic amputation of wrist and hand	0.647	0.353
O26.8 Other specified pregnancy-related conditions	0.646	0.354
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.646	0.354
S00.9 Superficial injury of head, part unspecified	0.646	0.354
I74.5 Embolism and thrombosis of iliac artery	0.645	0.355
M25.2 Flail joint	0.645	0.355
M25.1 Fistula of joint	0.645	0.355
M21.4 Flat foot [pes planus] (acquired)	0.645	0.355
M35.7 Hypermobility syndrome	0.645	0.355
H18.9 Disorder of cornea, unspecified	0.644	0.355
H18.7 Other corneal deformities	0.644	0.355
H18.3 Changes in corneal membranes	0.644	0.355
H18.1 Bullous keratopathy	0.644	0.355
H18.0 Corneal pigmentations and deposits	0.644	0.355
X60-X84 Intentional self-harm	0.644	0.355
I72.3 Aneurysm of iliac artery	0.644	0.356
Z35.5 Supervision of elderly primigravida	0.644	0.356
S64 Injury of nerves at wrist and hand level	0.644	0.356
Z11 Special screening examination for infectious and parasitic diseases	0.643	0.356
I51.8 Other ill-defined heart diseases	0.643	0.357
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.643	0.357
B99 Other and unspecified infectious diseases	0.643	0.357
I51.0 Cardiac septal defect, acquired	0.642	0.358
S70 Superficial injury of hip and thigh	0.642	0.358
A49.8 Other bacterial infections of unspecified site	0.642	0.358
Z01.6 Radiological examination, not elsewhere classified	0.642	0.358
I95-I99 Other and unspecified disorders of the circulatory system	0.642	0.358
Z04 Examination and observation for other reasons	0.642	0.358
T79-T79 Certain early complications of trauma	0.642	0.358
O24.4 Diabetes mellitus arising in pregnancy	0.642	0.358
Z02.9 Examination for administrative purposes, unspecified	0.641	0.359
Z02.7 Issue of medical certificate	0.641	0.359
Z02.6 Examination for insurance purposes	0.641	0.359
Z02.5 Examination for participation in sport	0.641	0.359
Z02.4 Examination for driving licence	0.641	0.359
Z02.3 Examination for recruitment to armed forces	0.641	0.359
Z02.2 Examination for admission to residential institution	0.641	0.359
Z02.1 Pre-employment examination	0.641	0.359
Z02.0 Examination for admission to educational institution	0.641	0.359
S00.2 Other superficial injuries of eyelid and periocular area	0.640	0.360
O40 Polyhydramnios	0.640	0.360
W07 Fall involving chair	0.640	0.360
M62 Other disorders of muscle	0.639	0.361
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.639	0.361
O64 Obstructed labour due to malposition and malpresentation of foetus	0.639	0.361
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.639	0.361
Z31 Procreative management	0.638	0.361
I47.9 Paroxysmal tachycardia, unspecified	0.638	0.362
H60-H62 Diseases of external ear	0.638	0.362
I05 Rheumatic mitral valve diseases	0.637	0.363
Y40.3 Macrolides	0.636	0.364
Z60 Problems related to social environment	0.636	0.364
Z36.5 Antenatal screening for isoimmunisation	0.636	0.364
G50.0 Trigeminal neuralgia	0.636	0.364
H18.8 Other specified disorders of cornea	0.635	0.364
I49.2 Junctional premature depolarisation	0.635	0.365
M31.9 Necrotising vasculopathy, unspecified	0.635	0.365
M31.8 Other specified necrotising vasculopathies	0.635	0.365
M31.7 Microscopic polyangiitis	0.635	0.365
M31.4 Aortic arch syndrome [Takayasu]	0.635	0.365
M31.2 Lethal midline granuloma	0.635	0.365
M31.1 Thrombotic microangiopathy	0.635	0.365
M31.0 Hypersensitivity angiitis	0.635	0.365
Y45.2 Propionic acid derivatives	0.635	0.365
O34 Maternal care for known or suspected abnormality of pelvic organs	0.634	0.365
O61 Failed induction of labour	0.634	0.366
W17 Other fall from one level to another	0.634	0.366
G00-G09 Inflammatory diseases of the central nervous system	0.634	0.366
O43 Placental disorders	0.634	0.366
I77.5 Necrosis of artery	0.634	0.366
I77.4 Coeliac artery compression syndrome	0.634	0.366
I77.3 Arterial fibromuscular dysplasia	0.634	0.366
I77.2 Rupture of artery	0.634	0.366
Y45.8 Other analgesics and antipyretics	0.633	0.367
B17 Other acute viral hepatitis	0.633	0.367
M34.8 Other forms of systemic sclerosis	0.633	0.367
M34.2 Systemic sclerosis induced by drugs and chemicals	0.633	0.367
M34.0 Progressive systemic sclerosis	0.633	0.367
I70 Atherosclerosis	0.633	0.367
M25.79 Osteophyte (Site unspecified)	0.632	0.367
M25.73 Osteophyte (Forearm)	0.632	0.367
M25.70 Osteophyte (Multiple sites)	0.632	0.367
Y57 Other and unspecified drugs and medicaments	0.632	0.367
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.632	0.368
M35.9 Systemic involvement of connective tissue, unspecified	0.632	0.368
M35.8 Other specified systemic involvement of connective tissue	0.632	0.368
M35.6 Relapsing panniculitis [Weber-Christian]	0.632	0.368
M35.5 Multifocal fibrosclerosis	0.632	0.368
M35.4 Diffuse (eosinophilic) fasciitis	0.632	0.368
M35.2 Behcet's disease	0.632	0.368
M35.1 Other overlap syndromes	0.632	0.368
O75.7 Vaginal delivery following previous Caesarean section	0.632	0.368
M24.5 Contracture of joint	0.631	0.369
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.631	0.369
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.631	0.369
I34.8 Other nonrheumatic mitral valve disorders	0.630	0.370
I34.2 Nonrheumatic mitral (valve) stenosis	0.630	0.370
I74.8 Embolism and thrombosis of other arteries	0.630	0.370
M24.0 Loose body in joint	0.630	0.370
Y41 Other systemic anti-infectives and antiparasitics	0.629	0.370
B18 Chronic viral hepatitis	0.629	0.370
S71 Open wound of hip and thigh	0.629	0.371
V18 Pedal cyclist injured in noncollision transport accident	0.629	0.371
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.628	0.371
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.628	0.372
Z65 Problems related to other psychosocial circumstances	0.628	0.372
Z64 Problems related to certain psychosocial circumstances	0.628	0.372
Z62 Other problems related to upbringing	0.628	0.372
Z61 Problems related to negative life events in childhood	0.628	0.372
Z59 Problems related to housing and economic circumstances	0.628	0.372
Z58 Problems related to physical environment	0.628	0.372
Z56 Problems related to employment and unemployment	0.628	0.372
Z55 Problems related to education and literacy	0.628	0.372
M05 Seropositive rheumatoid arthritis	0.628	0.372
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.627	0.373
M02 Reactive arthropathies	0.627	0.373

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations