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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12483148
log Bayes Factor = <0.0001
Chromosome 21   position 37,013,621  (GRCh37) Explore rs12483148 on Ensembl!
Variant rs12483148 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K56.6 Other and unspecified intestinal obstruction
0.021 0.979 0.000
D45 Polycythaemia vera
0.020 0.980 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.016 0.984 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.015 0.985 0.000
D47.1 Chronic myeloproliferative disease
0.014 0.986 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.013 0.987 0.000
D47.4 Osteomyelofibrosis
0.012 0.988 0.000
D46 Myelodysplastic syndromes
0.011 0.989 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.011 0.989 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.011 0.989 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.011 0.989 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.011 0.989 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.010 0.990 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.010 0.990 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.009 0.991 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.009 0.991 0.000
D43.0 Brain, supratentorial
0.009 0.991 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.009 0.991 0.000
D47.2 Monoclonal gammopathy
0.008 0.992 0.000
D46.7 Other myelodysplastic syndromes
0.008 0.992 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.008 0.992 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.008 0.992 0.000
D46.4 Refractory anaemia, unspecified
0.008 0.992 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.008 0.992 0.000
D46.1 Refractory anaemia with sideroblasts
0.008 0.992 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.008 0.992 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.008 0.992 0.000
D43.4 Spinal cord
0.008 0.992 0.000
D46.2 Refractory anaemia with excess of blasts
0.008 0.992 0.000
D43.9 Central nervous system, unspecified
0.008 0.992 0.000
D43.7 Other parts of central nervous system
0.008 0.992 0.000
D43.3 Cranial nerves
0.008 0.992 0.000
D43.1 Brain, infratentorial
0.008 0.992 0.000
D40.1 Testis
0.008 0.992 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.008 0.992 0.000
D43.2 Brain, unspecified
0.007 0.992 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.007 0.993 0.000
D37.0 Lip, oral cavity and pharynx
0.007 0.993 0.000
D44.8 Pluriglandular involvement
0.007 0.993 0.000
D42.9 Meninges, unspecified
0.007 0.993 0.000
D42.1 Spinal meninges
0.007 0.993 0.000
D42.0 Cerebral meninges
0.007 0.993 0.000
D40.9 Male genital organ, unspecified
0.007 0.993 0.000
D40.7 Other male genital organs
0.007 0.993 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.007 0.993 0.000
D44.9 Endocrine gland, unspecified
0.006 0.993 0.000
D44.7 Aortic body and other paraganglia
0.006 0.993 0.000
D44.6 Carotid body
0.006 0.993 0.000
D44.5 Pineal gland
0.006 0.993 0.000
D44.2 Parathyroid gland
0.006 0.993 0.000
D44.0 Thyroid gland
0.006 0.993 0.000
D44.1 Adrenal gland
0.006 0.994 0.000
D44.4 Craniopharyngeal duct
0.006 0.994 0.000
D39.9 Female genital organ, unspecified
0.006 0.994 0.000
D39.7 Other female genital organs
0.006 0.994 0.000
D39.2 Placenta
0.006 0.994 0.000
D39.0 Uterus
0.006 0.994 0.000
R23.3 Spontaneous ecchymoses
0.006 0.994 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.006 0.994 0.000
D44.3 Pituitary gland
0.006 0.994 0.000
D37.3 Appendix
0.006 0.994 0.000
D37.5 Rectum
0.006 0.994 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.005 0.994 0.000
D38.6 Respiratory organ, unspecified
0.005 0.994 0.000
D38.5 Other respiratory organs
0.005 0.994 0.000
D38.4 Thymus
0.005 0.994 0.000
D38.3 Mediastinum
0.005 0.994 0.000
D38.2 Pleura
0.005 0.994 0.000
D38.0 Larynx
0.005 0.994 0.000
D37.9 Digestive organ, unspecified
0.005 0.994 0.000
D37.2 Small intestine
0.005 0.995 0.000
D37.7 Other digestive organs
0.005 0.995 0.000
D39.1 Ovary
0.005 0.995 0.000
D48.7 Other specified sites
0.005 0.995 0.000
D37.6 Liver, gallbladder and bile ducts
0.005 0.995 0.000
D40.0 Prostate
0.005 0.995 0.000
D48.4 Peritoneum
0.005 0.995 0.000
D48.3 Retroperitoneum
0.005 0.995 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.005 0.995 0.000
D48.5 Skin
0.005 0.995 0.000
D37.4 Colon
0.005 0.995 0.000
D48.0 Bone and articular cartilage
0.004 0.995 0.000
R23.1 Pallor
0.005 0.995 0.000
D37.1 Stomach
0.004 0.995 0.000
R23 Other skin changes
0.004 0.996 0.000
O72.1 Other immediate postpartum haemorrhage
0.000 0.996 0.004
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.004 0.996 0.000
R23.0 Cyanosis
0.004 0.996 0.000
D48.6 Breast
0.004 0.996 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.996 0.004
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.000 0.996 0.004
D38.1 Trachea, bronchus and lung
0.003 0.996 0.001
D48.1 Connective and other soft tissue
0.003 0.997 0.000
D41.9 Urinary organ, unspecified
0.003 0.997 0.000
D41.7 Other urinary organs
0.003 0.997 0.000
D41.3 Urethra
0.003 0.997 0.000
D41.2 Ureter
0.003 0.997 0.000
D41.1 Renal pelvis
0.003 0.997 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.997 0.003
M16.9 Coxarthrosis, unspecified
0.000 0.997 0.003
R23.4 Changes in skin texture
0.003 0.997 0.000
M13.94 Arthritis, unspecified (Hand)
0.003 0.997 0.000
H66.9 Otitis media, unspecified
0.003 0.997 0.000
I45.1 Other and unspecified right bundle-branch block
0.000 0.997 0.003
Z94.8 Other transplanted organ and tissue status
0.003 0.997 0.000
R23.2 Flushing
0.003 0.997 0.000
R23.8 Other and unspecified skin changes
0.003 0.997 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.000 0.997 0.003
M22.4 Chondromalacia patellae
0.003 0.997 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.002 0.998 0.000
R80 Isolated proteinuria
0.002 0.998 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.002 0.998 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.000 0.998 0.002
S72.00 Fracture of neck of femur (closed)
0.000 0.998 0.002
H66 Suppurative and unspecified otitis media
0.002 0.998 0.000
H11.0 Pterygium
0.000 0.998 0.002
R63.0 Anorexia
0.002 0.998 0.000
I49.9 Cardiac arrhythmia, unspecified
0.002 0.998 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.998 0.002
D41.0 Kidney
0.001 0.998 0.001
H66.4 Suppurative otitis media, unspecified
0.002 0.998 0.000
I44.2 Atrioventricular block, complete
0.000 0.998 0.002
C91.4 Hairy-cell leukaemia
0.002 0.998 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.002 0.998 0.000
H66.0 Acute suppurative otitis media
0.002 0.998 0.000
H80.9 Otosclerosis, unspecified
0.002 0.998 0.000
R22.1 Localised swelling, mass and lump, neck
0.002 0.998 0.000
N02.8 Other
0.002 0.998 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.000 0.998 0.002
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.002 0.998 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.002 0.998 0.000
K59.3 Megacolon, not elsewhere classified
0.000 0.998 0.002
J02.9 Acute pharyngitis, unspecified
0.002 0.998 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.002 0.998 0.000
R22.2 Localised swelling, mass and lump, trunk
0.002 0.998 0.000
H18.5 Hereditary corneal dystrophies
0.000 0.998 0.002
R22.7 Localised swelling, mass and lump, multiple sites
0.002 0.998 0.000
C81 Hodgkin's disease
0.002 0.998 0.000
C81.0 Lymphocytic predominance
0.002 0.998 0.000
J92.0 Pleural plaque with presence of asbestos
0.000 0.998 0.002
C81.7 Other Hodgkin's disease
0.002 0.998 0.000
R22.0 Localised swelling, mass and lump, head
0.002 0.998 0.000
C81.2 Mixed cellularity
0.002 0.998 0.000
I45.3 Trifascicular block
0.000 0.998 0.002
C81.1 Nodular sclerosis
0.002 0.998 0.000
C95.9 Leukaemia, unspecified
0.002 0.998 0.000
K12.1 Other forms of stomatitis
0.002 0.998 0.000
H18.8 Other specified disorders of cornea
0.000 0.998 0.002
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.002 0.998 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.998 0.002
H11.3 Conjunctival haemorrhage
0.000 0.998 0.002
H66.3 Other chronic suppurative otitis media
0.002 0.998 0.000
H71 Cholesteatoma of middle ear
0.002 0.998 0.000
S72.0 Fracture of neck of femur
0.000 0.998 0.002
C91 Lymphoid leukaemia
0.002 0.998 0.000
C86 Other specified types of T/NK-cell lymphoma
0.002 0.998 0.000
H11 Other disorders of conjunctiva
0.000 0.998 0.002
H11.1 Conjunctival degenerations and deposits
0.000 0.998 0.002
B97 Viral agents as the cause of diseases classified to other chapters
0.000 0.998 0.002
H18.9 Disorder of cornea, unspecified
0.000 0.998 0.002
C91.9 Lymphoid leukaemia, unspecified
0.002 0.998 0.000
C95 Leukaemia of unspecified cell type
0.002 0.998 0.000
I45.5 Other specified heart block
0.000 0.998 0.002
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.002 0.998 0.000
A63.0 Anogenital (venereal) warts
0.002 0.998 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.001 0.998 0.000
C81.3 Lymphocytic depletion
0.001 0.998 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.998 0.002
C43.9 Malignant melanoma of skin, unspecified
0.000 0.998 0.002
M25.76 Osteophyte (Lower leg)
0.002 0.998 0.000
H18.2 Other corneal oedema
0.000 0.998 0.001
H18 Other disorders of cornea
0.000 0.998 0.002
I27.0 Primary pulmonary hypertension
0.002 0.998 0.000
Y57.9 Drug or medicament, unspecified
0.000 0.998 0.002
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.002 0.998 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.000 0.998 0.002
S72.01 Fracture of neck of femur (open)
0.000 0.998 0.001
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.001 0.998 0.000
C86.4 Blastic NK-cell lymphoma
0.001 0.998 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.001 0.998 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.001 0.998 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.001 0.998 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.001 0.998 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.001 0.998 0.000
C91.7 Other lymphoid leukaemia
0.001 0.998 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.001 0.998 0.000
C91.5 Adult T-cell leukaemia
0.001 0.998 0.000
C91.3 Prolymphocytic leukaemia
0.001 0.998 0.000
C91.2 Subacute lymphocytic leukaemia
0.001 0.998 0.000
H11.8 Other specified disorders of conjunctiva
0.000 0.998 0.001
H11.2 Conjunctival scars
0.000 0.998 0.001
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.000 0.999 0.001
B97.5 Reovirus as the cause of diseases classified to other chapters
0.000 0.999 0.001
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.000 0.999 0.001
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.000 0.999 0.001
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.000 0.999 0.001
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.000 0.999 0.001
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.000 0.999 0.001
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.001 0.999 0.000
C82.3 Follicular lymphoma grade IIIa
0.001 0.999 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.000 0.999 0.001
C67.2 Lateral wall of bladder
0.001 0.999 0.000
C95.7 Other leukaemia of unspecified cell type
0.001 0.999 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.001 0.999 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.001 0.999 0.000
C95.0 Acute leukaemia of unspecified cell type
0.001 0.999 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.999 0.001
I45 Other conduction disorders
0.000 0.999 0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.999 0.001
I35.1 Aortic (valve) insufficiency
0.000 0.999 0.001
C15.5 Lower third of oesophagus
0.001 0.999 0.000
C82.4 Follicular lymphoma grade IIIb
0.001 0.999 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.999 0.001
H11.4 Other conjunctival vascular disorders and cysts
0.000 0.999 0.001
C88 Malignant immunoproliferative diseases
0.001 0.999 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.001 0.999 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.000 0.999 0.001
H18.7 Other corneal deformities
0.000 0.999 0.001
H18.3 Changes in corneal membranes
0.000 0.999 0.001
H18.0 Corneal pigmentations and deposits
0.000 0.999 0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.999 0.001
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.001 0.999 0.000
C94 Other leukaemias of specified cell type
0.001 0.999 0.000
C93 Monocytic leukaemia
0.001 0.999 0.000
S72.30 Fracture of shaft of femur (closed)
0.000 0.999 0.001
C15.3 Upper third of oesophagus
0.001 0.999 0.000
I45.9 Conduction disorder, unspecified
0.000 0.999 0.001
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.001 0.999 0.000
C91.0 Acute lymphoblastic leukaemia
0.001 0.999 0.000
G83.4 Cauda equina syndrome
0.001 0.999 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.001 0.999 0.000
R68.8 Other specified general symptoms and signs
0.001 0.999 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.001 0.999 0.000
H18.6 Keratoconus
0.000 0.999 0.001
H18.4 Corneal degeneration
0.000 0.999 0.001
K83.1 Obstruction of bile duct
0.001 0.999 0.000
O14.0 Moderate preeclampsia
0.001 0.999 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.001 0.999 0.000
H11.9 Disorder of conjunctiva, unspecified
0.000 0.999 0.001
I45.0 Right fascicular block
0.000 0.999 0.001
R09.1 Pleurisy
0.000 0.999 0.001
C84.4 Peripheral T-cell lymphoma
0.001 0.999 0.000
C91.1 Chronic lymphocytic leukaemia
0.001 0.999 0.000
I45.4 Nonspecific intraventricular block
0.000 0.999 0.001
M79.0 Rheumatism, unspecified
0.000 0.999 0.001
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.999 0.001
C81.9 Hodgkin's disease, unspecified
0.001 0.999 0.000
C82.6 Cutaneous follicle centre lymphoma
0.001 0.999 0.000
C82.5 Diffuse follicle centre lymphoma
0.001 0.999 0.000
C82.2 Large cell, follicular
0.001 0.999 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.001 0.999 0.000
C88.7 Other malignant immunoproliferative diseases
0.001 0.999 0.000
C88.3 Immunoproliferative small intestinal disease
0.001 0.999 0.000
C88.2 Gamma heavy chain disease
0.001 0.999 0.000
C88.1 Alpha heavy chain disease
0.001 0.999 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.999 0.001
Z31.2 In vitro fertilisation
0.000 0.999 0.001
C93.9 Monocytic leukaemia, unspecified
0.001 0.999 0.000
C93.7 Other monocytic leukaemia
0.001 0.999 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.001 0.999 0.000
C93.2 Subacute monocytic leukaemia
0.001 0.999 0.000
C93.1 Chronic monocytic leukaemia
0.001 0.999 0.000
C93.0 Acute monocytic leukaemia
0.001 0.999 0.000
C94.7 Other specified leukaemias
0.001 0.999 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.001 0.999 0.000
C94.5 Acute myelofibrosis
0.001 0.999 0.000
C94.4 Acute panmyelosis
0.001 0.999 0.000
C94.3 Mast cell leukaemia
0.001 0.999 0.000
C94.2 Acute megakaryoblastic leukaemia
0.001 0.999 0.000
C94.1 Chronic erythraemia
0.001 0.999 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.001 0.999 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.001 0.999 0.000
C96.8 Histiocytic sarcoma
0.001 0.999 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.001 0.999 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.001 0.999 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.001 0.999 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.001 0.999 0.000
C96.3 True histiocytic lymphoma
0.001 0.999 0.000
C96.2 Malignant mast cell tumour
0.001 0.999 0.000
C96.1 Malignant histiocytosis
0.001 0.999 0.000
C96.0 Letterer-Siwe disease
0.001 0.999 0.000
D41.4 Bladder
0.001 0.999 0.000
H18.1 Bullous keratopathy
0.000 0.999 0.001
M06.9 Rheumatoid arthritis, unspecified
0.000 0.999 0.001
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.999 0.001
I65.2 Occlusion and stenosis of carotid artery
0.001 0.999 0.000
K10.8 Other specified diseases of jaws
0.000 0.999 0.001
K51.5 Mucosal proctocolitis
0.001 0.999 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.000 0.999 0.001
S72.3 Fracture of shaft of femur
0.000 0.999 0.001
T92.1 Sequelae of fracture of arm
0.001 0.999 0.000
Z45.8 Adjustment and management of other implanted devices
0.000 0.999 0.001
R21 Rash and other nonspecific skin eruption
0.001 0.999 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.001 0.999 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.001 0.999 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.001 0.999 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.001 0.999 0.000
C84.3 Lymphoepithelioid lymphoma
0.001 0.999 0.000
C84.2 T-zone lymphoma
0.001 0.999 0.000
C84.1 Sezary's diease
0.001 0.999 0.000
C84.0 Mycosis fungoides
0.001 0.999 0.000
Z47.8 Other specified orthopaedic follow-up care
0.000 0.999 0.001
C15.9 Oesophagus, unspecified
0.001 0.999 0.000
C15.4 Middle third of oesophagus
0.001 0.999 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.001 0.999 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.001 0.999 0.000
I77.6 Arteritis, unspecified
0.001 0.999 0.000
K51.8 Other ulcerative colitis
0.001 0.999 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.999 0.001
Z39.0 Care and examination immediately after delivery
0.000 0.999 0.001
M79.07 Rheumatism, unspecified (Ankle and foot)
0.000 0.999 0.001
M79.06 Rheumatism, unspecified (Lower leg)
0.000 0.999 0.001
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.000 0.999 0.001
M79.04 Rheumatism, unspecified (Hand)
0.000 0.999 0.001
M79.03 Rheumatism, unspecified (Forearm)
0.000 0.999 0.001
M79.02 Rheumatism, unspecified (Upper arm)
0.000 0.999 0.001
M79.01 Rheumatism, unspecified (Shoulder region)
0.000 0.999 0.001
E27.2 Addisonian crisis
0.000 0.999 0.001
I35.9 Aortic valve disorder, unspecified
0.000 0.999 0.001
N97.9 Female infertility, unspecified
0.000 0.999 0.001
O12.1 Gestational proteinuria
0.001 0.999 0.000
C15 Malignant neoplasm of oesophagus
0.001 0.999 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.999 0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.000 0.999 0.001
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.000 0.999 0.001
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.000 0.999 0.001
M96.5 Postradiation scoliosis
0.000 0.999 0.001
M96.4 Postsurgical lordosis
0.000 0.999 0.001
M96.3 Postlaminectomy kyphosis
0.000 0.999 0.001
M96.2 Postradiation kyphosis
0.000 0.999 0.001
O12.2 Gestational oedema with proteinuria
0.001 0.999 0.000
S05.1 Contusion of eyeball and orbital tissues
0.001 0.999 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.001 0.999 0.000
S72.31 Fracture of shaft of femur (open)
0.000 0.999 0.001
C90.1 Plasma cell leukaemia
0.001 0.999 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.001 0.999 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.001 0.999 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.001 0.999 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.999 0.001
C82.0 Small cleaved cell, follicular
0.001 0.999 0.000
C90.3 Solitary plasmacytoma
0.001 0.999 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.999 0.001
T84.1 Mechanical complication of internal fixation device of bones of limb
0.000 0.999 0.001
C92 Myeloid leukaemia
0.001 0.999 0.000
C15.8 Overlapping lesion of oesophagus
0.001 0.999 0.000
C15.2 Abdominal part of oesophagus
0.001 0.999 0.000
C15.1 Thoracic part of oesophagus
0.001 0.999 0.000
C15.0 Cervical part of oesophagus
0.001 0.999 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.999 0.001
J02.8 Acute pharyngitis due to other specified organisms
0.001 0.999 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.000 0.999 0.001
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)
0.000 0.999 0.001
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate
0.000 0.999 0.001
C82.1 Mixed small cleaved and large cell, follicular
0.001 0.999 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.001 0.999 0.000
C85.0 Lymphosarcoma
0.001 0.999 0.000
G83.1 Monoplegia of lower limb
0.001 0.999 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.001 0.999 0.000
O14.1 Severe preeclampsia
0.001 0.999 0.000
S06.8 Other intracranial injuries
0.000 0.999 0.001
S72 Fracture of femur
0.000 0.999 0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.999 0.001
M79.08 Rheumatism, unspecified (Other)
0.000 0.999 0.001
S02.10 Fracture of base of skull (closed)
0.000 0.999 0.001
B18.2 Chronic viral hepatitis C
0.001 0.999 0.000
C92.9 Myeloid leukaemia, unspecified
0.001 0.999 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.001 0.999 0.000
C92.7 Other myeloid leukaemia
0.001 0.999 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.001 0.999 0.000
C92.5 Acute myelomonocytic leukaemia
0.001 0.999 0.000
C92.4 Acute promyelocytic leukaemia
0.001 0.999 0.000
C92.3 Myeloid sarcoma
0.001 0.999 0.000
C92.2 Subacute myeloid leukaemia
0.001 0.999 0.000
J02.0 Streptococcal pharyngitis
0.001 0.999 0.000
K10.2 Inflammatory conditions of jaws
0.000 0.999 0.001
M06.0 Seronegative rheumatoid arthritis
0.000 0.999 0.001
M95.0 Acquired deformity of nose
0.000 0.999 0.001
N02.0 Minor glomerular abnormality
0.001 0.999 0.000
O14.9 Preeclampsia, unspecified
0.001 0.999 0.000
O14.2 HELLP syndrome
0.001 0.999 0.000
E27 Other disorders of adrenal gland
0.000 0.999 0.001
M06.34 Rheumatoid nodule (Hand)
0.000 0.999 0.001
S06.81 Other intracranial injuries (with open intracranial wound)
0.000 0.999 0.001
C84.5 Other and unspecified T-cell lymphomas
0.001 0.999 0.000
C85.1 B-cell lymphoma, unspecified
0.001 0.999 0.000
I45.8 Other specified conduction disorders
0.000 0.999 0.001
K57.2 Diverticular disease of large intestine with perforation and abscess
0.001 0.999 0.000
K62.3 Rectal prolapse
0.000 0.999 0.001
O28.1 Abnormal biochemical finding on antenatal screening of mother
0.001 0.999 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.001 0.999 0.000
J02 Acute pharyngitis
0.001 0.999 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.999 0.001
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.999 0.001
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.999 0.001
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.999 0.001
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.999 0.001
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.999 0.001
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.999 0.001
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.999 0.001
E27.5 Adrenomedullary hyperfunction
0.000 0.999 0.001
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.999 0.001
E27.0 Other adrenocortical overactivity
0.000 0.999 0.001
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.001 0.999 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.000 0.999 0.001
S72.8 Fractures of other parts of femur
0.000 0.999 0.001
S72.7 Multiple fractures of femur
0.000 0.999 0.001
S81.8 Open wound of other parts of lower leg
0.001 0.999 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.001 0.999 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.001 0.999 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.999 0.001
H44.1 Other endophthalmitis
0.001 0.999 0.000
S72.4 Fracture of lower end of femur
0.000 0.999 0.001
H80 Otosclerosis
0.001 0.999 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.000 0.999 0.001
S72.41 Fracture of lower end of femur (open)
0.000 0.999 0.001
S72.71 Multiple fractures of femur (open)
0.000 0.999 0.001
S72.70 Multiple fractures of femur (closed)
0.000 0.999 0.001
S72.81 Fractures of other parts of femur (open)
0.000 0.999 0.001
S72.80 Fractures of other parts of femur (closed)
0.000 0.999 0.001
B34.9 Viral infection, unspecified
0.000 0.999 0.001
H80.8 Other otosclerosis
0.001 0.999 0.000
H80.2 Cochlear otosclerosis
0.001 0.999 0.000
H80.1 Otosclerosis involving oval window, obliterative
0.001 0.999 0.000
H80.0 Otosclerosis involving oval window, nonobliterative
0.001 0.999 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.001 0.999 0.000
M43.1 Spondylolisthesis
0.001 0.999 0.000
S72.9 Fracture of femur, part unspecified
0.000 0.999 0.001
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.001 0.999 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.000 0.999 0.001
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.001 0.999 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.001 0.999 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.001 0.999 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.001 0.999 0.000
M43.12 Spondylolisthesis (Cervical region)
0.001 0.999 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.001 0.999 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.001 0.999 0.000
S72.91 Fracture of femur, part unspecified (open)
0.000 0.999 0.001
E53.8 Deficiency of other specified B group vitamins
0.000 0.999 0.001
I45.2 Bifascicular block
0.000 0.999 0.001
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.001 0.999 0.000
Y45.8 Other analgesics and antipyretics
0.001 0.999 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.999 0.001
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.999 0.001
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.999 0.001
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.000 0.999 0.001
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.999 0.001
J38.2 Nodules of vocal cords
0.000 0.999 0.001
M06.3 Rheumatoid nodule
0.000 0.999 0.001
S01.5 Open wound of lip and oral cavity
0.001 0.999 0.000
S06.5 Traumatic subdural haemorrhage
0.000 0.999 0.001
S72.2 Subtrochanteric fracture
0.000 0.999 0.001
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.999 0.001
M06.38 Rheumatoid nodule (Other)
0.000 0.999 0.001
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.999 0.001
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.999 0.001
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.999 0.001
M06.33 Rheumatoid nodule (Forearm)
0.000 0.999 0.001
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.999 0.001
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.999 0.001
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.999 0.001
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.000 0.999 0.001
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.000 0.999 0.001
S72.21 Subtrochanteric fracture (open)
0.000 0.999 0.001
S72.40 Fracture of lower end of femur (closed)
0.000 0.999 0.001
C69.0 Conjunctiva
0.001 0.999 0.000
C90.2 Plasmacytoma, extramedullary
0.001 0.999 0.000
C92.1 Chronic myeloid leukaemia
0.001 0.999 0.000
G25.3 Myoclonus
0.000 0.999 0.001
J98.9 Respiratory disorder, unspecified
0.000 0.999 0.001
Y40.9 Systemic antibiotic, unspecified
0.001 0.999 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.001 0.999 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.999 0.001
S72.90 Fracture of femur, part unspecified (closed)
0.000 0.999 0.001
S92.20 Fracture of other tarsal bone(s) (closed)
0.000 0.999 0.001
A63.8 Other specified predominantly sexually transmitted diseases
0.001 0.999 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.001 0.999 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.001 0.999 0.000
I65.1 Occlusion and stenosis of basilar artery
0.001 0.999 0.000
M95.2 Other acquired deformity of head
0.000 0.999 0.001
N02.2 Diffuse membranous glomerulonephritis
0.001 0.999 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.001 0.999 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.999 0.001
M95.96 Acquired deformity of musculoskeletal system, unspecified
0.000 0.999 0.001
S72.11 Pertrochanteric fracture (open)
0.000 0.999 0.001
G83.8 Other specified paralytic syndromes
0.001 0.999 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.001 0.999 0.000
K90.0 Coeliac disease
0.000 0.999 0.001
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.999 0.001
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.999 0.001
M95.5 Acquired deformity of pelvis
0.000 0.999 0.001
M95.4 Acquired deformity of chest and rib
0.000 0.999 0.001
M95.3 Acquired deformity of neck
0.000 0.999 0.001
M95.1 Cauliflower ear
0.000 0.999 0.001
O03.4 Incomplete, without complication
0.001 0.999 0.000
Y48.4 Anaesthetic, unspecified
0.001 0.999 0.000
Z56.3 Stressful work schedule
0.001 0.999 0.000
Z59.2 Discord with neighbours, lodgers and landlord
0.001 0.999 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.999 0.001
M06.18 Adult-onset Still's disease (Other)
0.000 0.999 0.001
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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