TreeWAS – Variant ID: rs12515891

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M23 Internal derangement of knee	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.999	0.001
M70-M79 Other soft tissue disorders	0.999	0.001
M79 Other soft tissue disorders, not elsewhere classified	0.998	0.002
M23.3 Other meniscus derangements	0.996	0.004
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.995	0.005
M25 Other joint disorders, not elsewhere classified	0.994	0.006
M25.5 Pain in joint	0.991	0.009
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.989	0.011
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.987	0.013
M79.8 Other specified soft tissue disorders	0.976	0.024
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.974	0.026
M25.56 Pain in joint (Lower leg)	0.967	0.033
M77 Other enthesopathies	0.962	0.038
M65-M68 Disorders of synovium and tendon	0.957	0.043
M25.57 Pain in joint (Ankle and foot)	0.949	0.051
M79.6 Pain in limb	0.936	0.064
M79.86 Other specified soft tissue disorders (Lower leg)	0.936	0.064
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.935	0.065
M67 Other disorders of synovium and tendon	0.917	0.083
M23.4 Loose body in knee	0.911	0.089
M24 Other specific joint derangements	0.910	0.090
M91-M94 Chondropathies	0.910	0.090
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.898	0.102
M77.1 Lateral epicondylitis	0.886	0.114
M79.67 Pain in limb (Ankle and foot)	0.885	0.115
M67.8 Other specified disorders of synovium and tendon	0.883	0.117
M79.9 Soft tissue disorder, unspecified	0.859	0.141
M70 Soft tissue disorders related to use, overuse and pressure	0.856	0.144
M79.80 Other specified soft tissue disorders (Multiple sites)	0.841	0.159
M77.12 Lateral epicondylitis (Upper arm)	0.832	0.168
M79.5 Residual foreign body in soft tissue	0.828	0.172
M79.64 Pain in limb (Hand)	0.828	0.172
M80-M85 Disorders of bone density and structure	0.826	0.174
M15-M19 Arthrosis	0.824	0.176
M25.0 Haemarthrosis	0.824	0.176
M23.49 Loose body in knee-Unspec lig/men	0.818	0.182
M23.0 Cystic meniscus	0.817	0.183
M40-M43 Deforming dorsopathies	0.815	0.185
M25.58 Pain in joint (Other)	0.814	0.186
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.813	0.187
M79.60 Pain in limb (Multiple sites)	0.811	0.189
M23.5 Chronic instability of knee	0.810	0.190
M77.9 Enthesopathy, unspecified	0.808	0.192
M17.9 Gonarthrosis, unspecified	0.805	0.195
M25.53 Pain in joint (Forearm)	0.805	0.195
M17 Gonarthrosis [arthrosis of knee]	0.804	0.196
M94 Other disorders of cartilage	0.802	0.198
M60-M63 Disorders of muscles	0.790	0.210
M79.7 Fibromyalgia	0.784	0.216
M66 Spontaneous rupture of synovium and tendon	0.782	0.218
M76 Enthesopathies of lower limb, excluding foot	0.778	0.222
M24.2 Disorder of ligament	0.777	0.223
M79.2 Neuralgia and neuritis, unspecified	0.770	0.230
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.769	0.231
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.762	0.238
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.760	0.240
M25.50 Pain in joint (Multiple sites)	0.753	0.247
M95.0 Acquired deformity of nose	0.753	0.247
M79.82 Other specified soft tissue disorders (Upper arm)	0.749	0.251
M25.8 Other specified joint disorders	0.747	0.253
M25.3 Other instability of joint	0.746	0.254
M25.59 Pain in joint (Site unspecified)	0.743	0.257
M70.7 Other bursitis of hip	0.741	0.259
M25.55 Pain in joint (Pelvic region and thigh)	0.740	0.260
M77.5 Other enthesopathy of foot	0.739	0.261
M23.9 Internal derangement of knee, unspecified	0.738	0.261
M22 Disorders of patella	0.737	0.263
M23.43 Loose body in knee-Med lig/oth men	0.736	0.264
M77.0 Medial epicondylitis	0.732	0.268
M25.4 Effusion of joint	0.731	0.269
M31 Other necrotising vasculopathies	0.729	0.270
M94.8 Other specified disorders of cartilage	0.727	0.273
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.724	0.276
M79.1 Myalgia	0.723	0.277
M24.5 Contracture of joint	0.719	0.281
M23.6 Other spontaneous disruption of ligament(s) of knee	0.717	0.283
M23.1 Discoid meniscus (congenital)	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.716	0.284
M73 Soft tissue disorders in diseases classified elsewhere	0.716	0.284
M77.4 Metatarsalgia	0.716	0.284
M79.3 Panniculitis, unspecified	0.715	0.285
M23.37 Other meniscus derangements-Capsular lig	0.714	0.285
M23.30 Other meniscus derangements (Multiple sites)	0.714	0.286
M93 Other osteochondropathies	0.714	0.286
M25.2 Flail joint	0.713	0.287
M25.1 Fistula of joint	0.713	0.287
M00-M03 Infectious arthropathies	0.709	0.291
M92 Other juvenile osteochondrosis	0.706	0.294
M79.54 Residual foreign body in soft tissue (Hand)	0.706	0.294
M79.4 Hypertrophy of (infrapatellar) fat pad	0.706	0.294
M24.0 Loose body in joint	0.705	0.295
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.704	0.296
M79.61 Pain in limb (Shoulder region)	0.703	0.297
M79.69 Pain in limb (Site unspecified)	0.703	0.297
M25.06 Haemarthrosis (Lower leg)	0.702	0.298
M79.81 Other specified soft tissue disorders (Shoulder region)	0.700	0.300
M24.7 Protrusio acetabuli	0.700	0.300
M34 Systemic sclerosis	0.699	0.301
M24.8 Other specific joint derangements, not elsewhere classified	0.696	0.304
M67.1 Other contracture of tendon (sheath)	0.694	0.306
M30 Polyarteritis nodosa and related conditions	0.692	0.308
M77.8 Other enthesopathies, not elsewhere classified	0.690	0.310
M77.3 Calcaneal spur	0.690	0.310
M77.2 Periarthritis of wrist	0.690	0.310
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.689	0.311
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.686	0.314
M41 Scoliosis	0.683	0.317
M23.8 Other internal derangements of knee	0.683	0.317
M79.0 Rheumatism, unspecified	0.682	0.318
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.679	0.321
M15 Polyarthrosis	0.677	0.323
M24.27 Disorder of ligament (Ankle and foot)	0.675	0.325
M21 Other acquired deformities of limbs	0.674	0.326
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.674	0.326
M84 Disorders of continuity of bone	0.672	0.328
M85 Other disorders of bone density and structure	0.672	0.328
M79.68 Pain in limb (Other)	0.671	0.329
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.671	0.329
M66.0 Rupture of popliteal cyst	0.668	0.332
M25.84 Other specified joint disorders (Hand)	0.666	0.334
M25.54 Pain in joint (Hand)	0.666	0.334
M67.2 Synovial hypertrophy, not elsewhere classified	0.665	0.335
M70.75 Other bursitis of hip-Pelvic/Thigh	0.659	0.341
M50-M54 Other dorsopathies	0.659	0.341
M67.9 Disorder of synovium and tendon, unspecified	0.658	0.342
M67.4 Ganglion	0.658	0.342
M67.3 Transient synovitis	0.658	0.342
M67.0 Short Achilles tendon (acquired)	0.658	0.342
M25.52 Pain in joint (Upper arm)	0.655	0.345
M22.2 Patellofemoral disorders	0.655	0.345
M23.47 Loose body in knee-Capsular lig	0.653	0.347
M23.46 Loose body in knee-O/unsp lat men	0.653	0.347
M23.45 Loose body in knee-Pst hrn lat men	0.653	0.347
M23.44 Loose body in knee-Lat lig/ant men	0.653	0.347
M23.42 Loose body in knee-Pst lig/hrn men	0.653	0.347
M23.41 Loose body in knee-Ant lig/hrn men	0.653	0.347
M23.40 Loose body in knee-Mult sites	0.653	0.347
M25.9 Joint disorder, unspecified	0.653	0.347
M24.9 Joint derangement, unspecified	0.652	0.347
M24.6 Ankylosis of joint	0.652	0.347
M91 Juvenile osteochondrosis of hip and pelvis	0.652	0.348
M25.6 Stiffness of joint, not elsewhere classified	0.650	0.350
M70.6 Trochanteric bursitis	0.649	0.351
M79.88 Other specified soft tissue disorders (Other)	0.648	0.352
M79.79 Fibromyalgia (Site unspecified)	0.646	0.354
M99 Biomechanical lesions, not elsewhere classified	0.644	0.356
M79.65 Pain in limb (Pelvic region and thigh)	0.643	0.357
M62 Other disorders of muscle	0.640	0.360
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.637	0.363
M79.83 Other specified soft tissue disorders (Forearm)	0.636	0.363
M77.19 Lateral epicondylitis (Site unspecified)	0.636	0.364
M77.18 Lateral epicondylitis-Other	0.636	0.364
M77.17 Lateral epicondylitis-Ankle/Foot	0.636	0.364
M77.16 Lateral epicondylitis (Lower leg)	0.636	0.364
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.636	0.364
M77.14 Lateral epicondylitis-Hand	0.636	0.364
M77.13 Lateral epicondylitis-Forearm	0.636	0.364
M77.11 Lateral epicondylitis-Shldr region	0.636	0.364
M77.10 Lateral epicondylitis (Multiple sites)	0.636	0.364
M65 Synovitis and tenosynovitis	0.634	0.366
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.632	0.368
M70.2 Olecranon bursitis	0.631	0.368
M94.86 Other specified disorders of cartilage (Lower leg)	0.629	0.371
M71 Other bursopathies	0.628	0.372
M77.91 Enthesopathy, unspecified (Shoulder region)	0.625	0.375
M81 Osteoporosis without pathological fracture	0.622	0.378
M22.3 Other derangements of patella	0.622	0.378
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.621	0.379
M76.6 Achilles tendinitis	0.620	0.380
M31.3 Wegener's granulomatosis	0.618	0.382
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.616	0.384
M79.98 Soft tissue disorder, unspecified (Other)	0.616	0.384
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.616	0.384
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.616	0.384
M79.94 Soft tissue disorder, unspecified (Hand)	0.616	0.384
M79.93 Soft tissue disorder, unspecified (Forearm)	0.616	0.384
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.616	0.384
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.616	0.384
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.616	0.384
M79.63 Pain in limb (Forearm)	0.616	0.384
M94.88 Other specified disorders of cartilage (Other)	0.615	0.385
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.613	0.386
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.613	0.386
M70.5 Other bursitis of knee	0.613	0.386
M70.3 Other bursitis of elbow	0.613	0.386
M70.1 Bursitis of hand	0.613	0.386
M70.0 Chronic crepitant synovitis of hand and wrist	0.613	0.386
M24.4 Recurrent dislocation and subluxation of joint	0.611	0.389
M25.51 Pain in joint (Shoulder region)	0.610	0.390
M25.47 Effusion of joint (Ankle and foot)	0.608	0.392
M24.02 Loose body in joint (Upper arm)	0.599	0.401
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.594	0.406
M79.58 Residual foreign body in soft tissue (Other)	0.594	0.406
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.594	0.406
M79.56 Residual foreign body in soft tissue (Lower leg)	0.594	0.406
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.594	0.406
M79.53 Residual foreign body in soft tissue (Forearm)	0.594	0.406
M79.52 Residual foreign body in soft tissue (Upper arm)	0.594	0.406
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.594	0.406
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.594	0.406
M17.3 Other posttraumatic gonarthrosis	0.592	0.408
M83 Adult osteomalacia	0.592	0.408
M94.9 Disorder of cartilage, unspecified	0.591	0.409
M25.09 Haemarthrosis (Site unspecified)	0.591	0.409
M25.08 Haemarthrosis (Other)	0.591	0.409
M25.07 Haemarthrosis (Ankle and foot)	0.591	0.409
M25.05 Haemarthrosis (Pelvic region and thigh)	0.591	0.409
M25.04 Haemarthrosis (Hand)	0.591	0.409
M25.03 Haemarthrosis (Forearm)	0.591	0.409
M25.02 Haemarthrosis (Upper arm)	0.591	0.409
M25.01 Haemarthrosis (Shoulder region)	0.591	0.409
M25.00 Haemarthrosis (Multiple sites)	0.591	0.409
M40 Kyphosis and lordosis	0.588	0.412
M66.06 Rupture of popliteal cyst-Lower leg	0.586	0.414
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.586	0.414
M23.07 Cystic meniscus-Capsular lig	0.586	0.414
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.586	0.414
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.586	0.414
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.586	0.414
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.586	0.414
M23.00 Cystic meniscus (Multiple sites)	0.586	0.414
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.585	0.415
M85.8 Other specified disorders of bone density and structure	0.584	0.416
M42 Spinal osteochondrosis	0.584	0.416
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.584	0.416
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.583	0.417
M95.8 Other specified acquired deformities of musculoskeletal system	0.583	0.417
M95.5 Acquired deformity of pelvis	0.583	0.417
M95.4 Acquired deformity of chest and rib	0.583	0.417
M95.3 Acquired deformity of neck	0.583	0.417
M95.2 Other acquired deformity of head	0.583	0.417
M95.1 Cauliflower ear	0.583	0.417
M50 Cervical disk disorders	0.582	0.418
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.581	0.419
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.581	0.419
M23.57 Chronic instability of knee (Capsular ligament)	0.581	0.419
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.581	0.419
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.581	0.419
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.581	0.419
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.581	0.419
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.581	0.419
M23.50 Chronic instability of knee (Multiple sites)	0.581	0.419
M70.4 Prepatellar bursitis	0.580	0.420
M77.57 Other enthesopathy of foot-Ankle/Foot	0.580	0.420
M77.99 Enthesopathy, unspecified (Site unspecified)	0.580	0.420
M77.98 Enthesopathy, unspecified (Other)	0.580	0.420
M77.96 Enthesopathy, unspecified (Lower leg)	0.580	0.420
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.580	0.420
M77.94 Enthesopathy, unspecified (Hand)	0.580	0.420
M77.93 Enthesopathy, unspecified (Forearm)	0.580	0.420
M77.92 Enthesopathy, unspecified (Upper arm)	0.580	0.420
M77.90 Enthesopathy, unspecified (Multiple sites)	0.580	0.420
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.578	0.421
M43 Other deforming dorsopathies	0.578	0.422
M82 Osteoporosis in diseases classified elsewhere	0.578	0.422
M24.1 Other articular cartilage disorders	0.577	0.423
M17.4 Other secondary gonarthrosis, bilateral	0.576	0.423
M17.2 Posttraumatic gonarthrosis, bilateral	0.576	0.423
M94.3 Chondrolysis	0.575	0.425
M94.1 Relapsing polychondritis	0.575	0.425
M94.0 Chondrocostal junction syndrome [Tietze]	0.575	0.425
M84.0 Malunion of fracture	0.575	0.425
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.574	0.425
M93.9 Osteochondropathy, unspecified	0.573	0.427
M15.1 Heberden's nodes (with arthropathy)	0.571	0.429
M24.26 Disorder of ligament (Lower leg)	0.570	0.429
M63 Disorders of muscle in diseases classified elsewhere	0.566	0.433
M61 Calcification and ossification of muscle	0.566	0.433
M60 Myositis	0.566	0.433
M77.02 Medial epicondylitis (Upper arm)	0.567	0.433
M17.5 Other secondary gonarthrosis	0.566	0.434
M25.45 Effusion of joint (Pelvic region and thigh)	0.563	0.437
M79.78 Fibromyalgia (Other)	0.562	0.438
M79.77 Fibromyalgia (Ankle and foot)	0.562	0.438
M79.76 Fibromyalgia (Lower leg)	0.562	0.438
M79.75 Fibromyalgia (Pelvic region and thigh)	0.562	0.438
M79.74 Fibromyalgia (Hand)	0.562	0.438
M79.73 Fibromyalgia (Forearm)	0.562	0.438
M79.72 Fibromyalgia (Upper arm)	0.562	0.438
M79.71 Fibromyalgia (Shoulder region)	0.562	0.438
M66.5 Spontaneous rupture of unspecified tendon	0.561	0.439
M66.4 Spontaneous rupture of other tendons	0.561	0.439
M66.3 Spontaneous rupture of flexor tendons	0.561	0.439
M66.1 Rupture of synovium	0.561	0.439
M92.6 Juvenile osteochondrosis of tarsus	0.561	0.439
M25.81 Other specified joint disorders (Shoulder region)	0.561	0.439
M24.51 Contracture of joint (Shoulder region)	0.559	0.441
M41.9 Scoliosis, unspecified	0.559	0.441
M76.9 Enthesopathy of lower limb, unspecified	0.558	0.442
M76.8 Other enthesopathies of lower limb, excluding foot	0.558	0.442
M76.7 Peroneal tendinitis	0.558	0.442
M76.5 Patellar tendinitis	0.558	0.442
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]	0.558	0.442
M76.3 Iliotibial band syndrome	0.558	0.442
M76.2 Iliac crest spur	0.558	0.442
M76.1 Psoas tendinitis	0.558	0.442
M76.0 Gluteal tendinitis	0.558	0.442
M25.31 Other instability of joint (Shoulder region)	0.557	0.443
M24.29 Disorder of ligament (Site unspecified)	0.557	0.443
M24.28 Disorder of ligament (Other)	0.557	0.443
M24.25 Disorder of ligament (Pelvic region and thigh)	0.557	0.443
M24.24 Disorder of ligament (Hand)	0.557	0.443
M24.23 Disorder of ligament (Forearm)	0.557	0.443
M24.22 Disorder of ligament (Upper arm)	0.557	0.443
M24.21 Disorder of ligament (Shoulder region)	0.557	0.443
M24.20 Disorder of ligament (Multiple sites)	0.557	0.443
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.557	0.443
M79.10 Myalgia (Multiple sites)	0.555	0.444
M79.19 Myalgia (Site unspecified)	0.553	0.447
M79.28 Neuralgia and neuritis, unspecified (Other)	0.552	0.448
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.552	0.448
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.552	0.448
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.552	0.448
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.552	0.448
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.552	0.448
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.552	0.448
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.552	0.448
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.551	0.449
M94.2 Chondromalacia	0.551	0.449
M24.75 Protrusio acetabuli-Pelvic/thigh	0.549	0.451
M25.37 Other instability of joint (Ankle and foot)	0.546	0.453
M24.54 Contracture of joint (Hand)	0.546	0.454
M81.4 Drug-induced osteoporosis	0.545	0.455
M79.89 Other specified soft tissue disorders (Site unspecified)	0.542	0.458
M23.80 Other internal derangements of knee (Multiple sites)	0.541	0.459
M86-M90 Other osteopathies	0.540	0.460
M66.2 Spontaneous rupture of extensor tendons	0.539	0.460
M77.47 Metatarsalgia-Ankle/Foot	0.539	0.461
M79.70 Fibromyalgia (Multiple sites)	0.538	0.462
M41.8 Other forms of scoliosis	0.537	0.463
M25.89 Other specified joint disorders (Site unspecified)	0.536	0.464
M25.88 Other specified joint disorders (Other)	0.536	0.464
M25.83 Other specified joint disorders (Forearm)	0.536	0.464
M25.82 Other specified joint disorders (Upper arm)	0.536	0.464
M25.80 Other specified joint disorders (Multiple sites)	0.536	0.464
M25.39 Other instability of joint (Site unspecified)	0.535	0.465
M25.38 Other instability of joint (Other)	0.535	0.465
M25.36 Other instability of joint (Lower leg)	0.535	0.465
M25.35 Other instability of joint (Pelvic region and thigh)	0.535	0.465
M25.34 Other instability of joint (Hand)	0.535	0.465
M25.33 Other instability of joint (Forearm)	0.535	0.465
M25.32 Other instability of joint (Upper arm)	0.535	0.465
M25.30 Other instability of joint (Multiple sites)	0.535	0.465
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.534	0.465
M62.8 Other specified disorders of muscle	0.532	0.468
M70.79 Other bursitis of hip-Site unspec	0.531	0.469
M70.78 Other bursitis of hip-Other	0.531	0.469
M70.77 Other bursitis of hip-Ankle/Foot	0.531	0.469
M70.76 Other bursitis of hip-Lower Leg	0.531	0.469
M70.74 Other bursitis of hip-Hand	0.531	0.469
M70.73 Other bursitis of hip-Forearm	0.531	0.469
M70.72 Other bursitis of hip-Upper arm	0.531	0.469
M70.71 Other bursitis of hip-Shldr region	0.531	0.469
M70.70 Other bursitis of hip-Mult sites	0.531	0.469
M77.59 Other enthesopathy of foot-Site unspec	0.530	0.470
M77.58 Other enthesopathy of foot-Other	0.530	0.470
M77.56 Other enthesopathy of foot-Lower Leg	0.530	0.470
M77.55 Other enthesopathy of foot-Pelvic/Thigh	0.530	0.470
M77.54 Other enthesopathy of foot-Hand	0.530	0.470
M77.53 Other enthesopathy of foot-Forearm	0.530	0.470
M77.52 Other enthesopathy of foot-Upper arm	0.530	0.470
M77.51 Other enthesopathy of foot-Shldr region	0.530	0.470
M77.50 Other enthesopathy of foot-Mult sites	0.530	0.470
M79.00 Rheumatism, unspecified (Multiple sites)	0.530	0.470
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.529	0.470
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.529	0.470
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.529	0.470
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.529	0.470
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.529	0.470
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.529	0.470
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.529	0.470
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.529	0.470
M22.1 Recurrent subluxation of patella	0.528	0.471
M22.9 Disorder of patella, unspecified	0.528	0.471
M22.0 Recurrent dislocation of patella	0.528	0.471
M53 Other dorsopathies, not elsewhere classified	0.526	0.474
M77.09 Medial epicondylitis (Site unspecified)	0.525	0.475
M77.08 Medial epicondylitis-Other	0.525	0.475
M77.07 Medial epicondylitis-Ankle/Foot	0.525	0.475
M77.06 Medial epicondylitis (Lower leg)	0.525	0.475
M77.05 Medial epicondylitis (Pelvic region and thigh)	0.525	0.475
M77.04 Medial epicondylitis-Hand	0.525	0.475
M77.03 Medial epicondylitis-Forearm	0.525	0.475
M77.01 Medial epicondylitis-Shldr region	0.525	0.475
M77.00 Medial epicondylitis (Multiple sites)	0.525	0.475
M25.49 Effusion of joint (Site unspecified)	0.524	0.476
M25.48 Effusion of joint (Other)	0.524	0.476
M25.44 Effusion of joint (Hand)	0.524	0.476
M25.43 Effusion of joint (Forearm)	0.524	0.476
M25.42 Effusion of joint (Upper arm)	0.524	0.476
M25.41 Effusion of joint (Shoulder region)	0.524	0.476
M25.40 Effusion of joint (Multiple sites)	0.524	0.476
M31.9 Necrotising vasculopathy, unspecified	0.523	0.477
M31.8 Other specified necrotising vasculopathies	0.523	0.477
M31.7 Microscopic polyangiitis	0.523	0.477
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.523	0.477
M31.4 Aortic arch syndrome [Takayasu]	0.523	0.477
M31.2 Lethal midline granuloma	0.523	0.477
M31.1 Thrombotic microangiopathy	0.523	0.477
M31.0 Hypersensitivity angiitis	0.523	0.477
M79.62 Pain in limb (Upper arm)	0.523	0.477
M94.89 Other specified disorders of cartilage (Site unspecified)	0.521	0.478
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.521	0.478
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.521	0.478
M94.84 Other specified disorders of cartilage (Hand)	0.521	0.478
M94.83 Other specified disorders of cartilage (Forearm)	0.521	0.478
M94.82 Other specified disorders of cartilage (Upper arm)	0.521	0.478
M94.81 Other specified disorders of cartilage (Shoulder region)	0.521	0.478
M94.80 Other specified disorders of cartilage (Multiple sites)	0.521	0.478
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.521	0.479
M79.17 Myalgia (Ankle and foot)	0.519	0.481
M79.16 Myalgia (Lower leg)	0.519	0.481
M79.15 Myalgia (Pelvic region and thigh)	0.519	0.481
M79.14 Myalgia (Hand)	0.519	0.481
M79.13 Myalgia (Forearm)	0.519	0.481
M79.12 Myalgia (Upper arm)	0.519	0.481
M79.11 Myalgia (Shoulder region)	0.519	0.481
M80 Osteoporosis with pathological fracture	0.519	0.481
M50.1 Cervical disk disorder with radiculopathy	0.518	0.482
M24.59 Contracture of joint (Site unspecified)	0.516	0.484
M24.58 Contracture of joint (Other)	0.516	0.484
M24.57 Contracture of joint (Ankle and foot)	0.516	0.484
M24.56 Contracture of joint (Lower leg)	0.516	0.484
M24.55 Contracture of joint (Pelvic region and thigh)	0.516	0.484
M24.53 Contracture of joint (Forearm)	0.516	0.484
M24.52 Contracture of joint (Upper arm)	0.516	0.484
M24.50 Contracture of joint (Multiple sites)	0.516	0.484
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.514	0.486
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.514	0.486
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.514	0.486
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.514	0.486
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.514	0.486
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.514	0.486
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.514	0.486
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.514	0.486
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.514	0.486
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.514	0.486
M23.17 Discoid meniscus (congenital)-Capsular lig	0.514	0.486
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.514	0.486
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.514	0.486
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.514	0.486
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.514	0.486
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.514	0.486
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.514	0.486
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.514	0.486
M32.9 Systemic lupus erythematosus, unspecified	0.514	0.486
M32.8 Other forms of systemic lupus erythematosus	0.514	0.486
M32.1 Systemic lupus erythematosus with organ or system involvement	0.514	0.486
M32.0 Drug-induced systemic lupus erythematosus	0.514	0.486
M33.9 Dermatopolymyositis, unspecified	0.514	0.486
M33.2 Polymyositis	0.514	0.486
M33.1 Other dermatomyositis	0.514	0.486
M33.0 Juvenile dermatomyositis	0.514	0.486
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.514	0.486
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.514	0.486
M36.3 Arthropathy in other blood disorders	0.514	0.486
M36.2 Haemophilic arthropathy	0.514	0.486
M36.1 Arthropathy in neoplastic disease	0.514	0.486
M36.0 Dermato(poly)myositis in neoplastic disease	0.514	0.486
M24.01 Loose body in joint (Shoulder region)	0.514	0.486
M73.8 Other soft tissue disorders in diseases classified elsewhere	0.514	0.486
M73.1 Syphilitic bursitis	0.514	0.486
M73.0 Gonococcal bursitis	0.514	0.486
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.514	0.486
M77.49 Metatarsalgia-Site unspec	0.513	0.487
M77.48 Metatarsalgia-Other	0.513	0.487
M77.46 Metatarsalgia-Lower Leg	0.513	0.487
M77.45 Metatarsalgia-Pelvic/Thigh	0.513	0.487
M77.44 Metatarsalgia-Hand	0.513	0.487
M77.43 Metatarsalgia-Forearm	0.513	0.487
M77.42 Metatarsalgia-Upper arm	0.513	0.487
M77.41 Metatarsalgia-Shldr region	0.513	0.487
M77.40 Metatarsalgia-Mult sites	0.513	0.487
M79.39 Panniculitis, unspecified (Site unspecified)	0.513	0.487
M79.38 Panniculitis, unspecified (Other)	0.513	0.487
M79.37 Panniculitis, unspecified (Ankle and foot)	0.513	0.487
M79.36 Panniculitis, unspecified (Lower leg)	0.513	0.487
M79.35 Panniculitis, unspecified (Pelvic region and thigh)	0.513	0.487
M79.34 Panniculitis, unspecified (Hand)	0.513	0.487
M79.33 Panniculitis, unspecified (Forearm)	0.513	0.487
M79.32 Panniculitis, unspecified (Upper arm)	0.513	0.487
M79.31 Panniculitis, unspecified (Shoulder region)	0.513	0.487
M79.30 Panniculitis, unspecified (Multiple sites)	0.513	0.487
M93.8 Other specified osteochondropathies	0.512	0.488
M93.2 Osteochondritis dissecans	0.512	0.488
M93.1 Kienbock's disease of adults	0.512	0.488
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.512	0.488
M25.19 Fistula of joint (Site unspecified)	0.511	0.489
M25.18 Fistula of joint (Other)	0.511	0.489
M25.17 Fistula of joint (Ankle and foot)	0.511	0.489
M25.16 Fistula of joint (Lower leg)	0.511	0.489
M25.15 Fistula of joint (Pelvic region and thigh)	0.511	0.489
M25.14 Fistula of joint (Hand)	0.511	0.489
M25.13 Fistula of joint (Forearm)	0.511	0.489

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations