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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12524865
log Bayes Factor = 18.2244
Chromosome 6   position 134,196,674  (GRCh37) Explore rs12524865 on Ensembl!
Variant rs12524865 is listed in the   GWAS Catalog   ⇪
Variant rs12524865 is part of Cluster X0228

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
I21.9 Acute myocardial infarction, unspecified
0.000 0.004 0.996
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.008 0.992
I20 Angina pectoris
0.000 0.014 0.986
I20.9 Angina pectoris, unspecified
0.000 0.017 0.983
I25.5 Ischaemic cardiomyopathy
0.000 0.040 0.960
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.088 0.912
I22 Subsequent myocardial infarction
0.000 0.123 0.877
I21.4 Acute subendocardial myocardial infarction
0.000 0.151 0.849
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.189 0.811
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.200 0.800
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.224 0.776
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.256 0.744
I23 Certain current complications following acute myocardial infarction
0.000 0.258 0.742
I24 Other acute ischaemic heart diseases
0.000 0.261 0.739
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.272 0.728
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.284 0.716
I25.4 Coronary artery aneurysm
0.000 0.325 0.675
I20.1 Angina pectoris with documented spasm
0.000 0.363 0.637
I22.8 Subsequent myocardial infarction of other sites
0.000 0.382 0.617
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.393 0.607
I25.3 Aneurysm of heart
0.000 0.395 0.605
I20.8 Other forms of angina pectoris
0.000 0.405 0.595
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.409 0.591
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.411 0.589
I24.1 Dressler's syndrome
0.000 0.437 0.563
I23.8 Other current complications following acute myocardial infarction
0.000 0.442 0.558
I20.0 Unstable angina
0.000 0.466 0.534
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.468 0.532
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.468 0.532
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.468 0.532
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.468 0.532
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.468 0.532
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.468 0.532
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.468 0.532
I10-I15 Hypertensive diseases
0.000 0.487 0.513
I24.8 Other forms of acute ischaemic heart disease
0.000 0.515 0.485
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.520 0.480
I11 Hypertensive heart disease
0.000 0.605 0.395
I13 Hypertensive heart and renal disease
0.000 0.632 0.368
I15 Secondary hypertension
0.000 0.654 0.346
Chapter IX Diseases of the circulatory system
0.000 0.656 0.344
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.668 0.332
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.736 0.264
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.736 0.264
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.736 0.264
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.736 0.264
I15.8 Other secondary hypertension
0.000 0.752 0.248
I15.2 Hypertension secondary to endocrine disorders
0.000 0.752 0.248
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.754 0.246
I00-I02 Acute rheumatic fever
0.000 0.755 0.245
I15.0 Renovascular hypertension
0.000 0.756 0.244
I15.9 Seconday hypertension, unspecified
0.000 0.758 0.242
I15.1 Hypertension secondary to other renal disorders
0.000 0.762 0.238
I12 Hypertensive renal disease
0.000 0.807 0.193
I02 Rheumatic chorea
0.000 0.824 0.176
I01 Rheumatic fever with heart involvement
0.000 0.824 0.176
I00 Rheumatic fever without mention of heart involvement
0.000 0.826 0.174
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.867 0.133
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.874 0.126
I01.8 Other acute rheumatic heart disease
0.000 0.874 0.126
I01.2 Acute rheumatic myocarditis
0.000 0.874 0.126
I01.1 Acute rheumatic endocarditis
0.000 0.874 0.126
I01.0 Acute rheumatic pericarditis
0.000 0.874 0.126
I02.9 Rheumatic chorea without heart involvement
0.000 0.874 0.126
I02.0 Rheumatic chorea with heart involvement
0.000 0.874 0.126
I12.9 Hypertensive renal disease without renal failure
0.000 0.878 0.122
I05-I09 Chronic rheumatic heart diseases
0.000 0.879 0.121
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.900 0.100
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.906 0.094
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.913 0.087
I99 Other and unspecified disorders of circulatory system
0.000 0.913 0.087
I06 Rheumatic aortic valve diseases
0.000 0.916 0.084
I09 Other rheumatic heart diseases
0.000 0.918 0.082
I05 Rheumatic mitral valve diseases
0.000 0.924 0.076
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.927 0.073
I50.1 Left ventricular failure
0.000 0.930 0.070
K29.8 Duodenitis
0.000 0.931 0.069
I07 Rheumatic tricuspid valve diseases
0.000 0.931 0.069
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.932 0.068
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.932 0.068
I97.0 Postcardiotomy syndrome
0.000 0.932 0.068
I28 Other diseases of pulmonary vessels
0.000 0.935 0.065
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.936 0.064
I05.0 Mitral stenosis
0.000 0.937 0.063
I97.1 Other functional disturbances following cardiac surgery
0.000 0.937 0.063
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.937 0.063
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.937 0.063
I98.0 Cardiovascular syphilis
0.000 0.937 0.063
I06.0 Rheumatic aortic stenosis
0.000 0.937 0.063
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.940 0.060
I06.8 Other rheumatic aortic valve diseases
0.000 0.940 0.060
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.940 0.060
I08 Multiple valve diseases
0.000 0.940 0.060
I09.8 Other specified rheumatic heart diseases
0.000 0.941 0.059
I09.2 Chronic rheumatic pericarditis
0.000 0.941 0.059
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.941 0.059
I09.0 Rheumatic myocarditis
0.000 0.941 0.059
I05.8 Other mitral valve diseases
0.000 0.946 0.054
I06.1 Rheumatic aortic insufficiency
0.000 0.946 0.054
I05.2 Mitral stenosis with insufficiency
0.000 0.946 0.054
I09.9 Rheumatic heart disease, unspecified
0.000 0.946 0.053
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.948 0.052
I08.8 Other multiple valve diseases
0.000 0.950 0.050
I07.9 Tricuspid valve disease, unspecified
0.000 0.950 0.049
I07.8 Other tricuspid valve diseases
0.000 0.950 0.049
I07.2 Tricuspid stenosis with insufficiency
0.000 0.950 0.049
I07.0 Tricuspid stenosis
0.000 0.950 0.049
I26 Pulmonary embolism
0.000 0.951 0.049
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.953 0.047
I28.1 Aneurysm of pulmonary artery
0.000 0.953 0.047
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.953 0.047
I05.1 Rheumatic mitral insufficiency
0.000 0.953 0.047
I08.9 Multiple valve disease, unspecified
0.000 0.954 0.046
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.954 0.045
Z03.4 Observation for suspected myocardial infarction
0.000 0.958 0.042
I28.8 Other specified diseases of pulmonary vessels
0.000 0.960 0.040
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.962 0.038
I95 Hypotension
0.000 0.965 0.035
I05.9 Mitral valve disease, unspecified
0.000 0.966 0.034
I50 Heart failure
0.000 0.966 0.034
E78.5 Hyperlipidaemia, unspecified
0.000 0.967 0.033
N20 Calculus of kidney and ureter
0.000 0.967 0.033
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.967 0.032
N20.9 Urinary calculus, unspecified
0.000 0.968 0.032
N21 Calculus of lower urinary tract
0.000 0.968 0.032
N20-N23 Urolithiasis
0.000 0.969 0.031
N21.0 Calculus in bladder
0.000 0.969 0.031
I07.1 Tricuspid insufficiency
0.000 0.969 0.031
N21.1 Calculus in urethra
0.000 0.971 0.029
N23 Unspecified renal colic
0.000 0.972 0.028
N20.1 Calculus of ureter
0.000 0.972 0.028
N20.0 Calculus of kidney
0.000 0.972 0.028
I30-I52 Other forms of heart disease
0.000 0.972 0.028
I95.8 Other hypotension
0.000 0.972 0.028
I49.8 Other specified cardiac arrhythmias
0.000 0.973 0.027
I46.0 Cardiac arrest with successful resuscitation
0.000 0.973 0.027
I49 Other cardiac arrhythmias
0.000 0.974 0.026
I46 Cardiac arrest
0.000 0.974 0.026
I95.0 Idiopathic hypotension
0.000 0.974 0.026
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.024 0.976 0.000
I49.1 Atrial premature depolarisation
0.000 0.977 0.023
N21.9 Calculus of lower urinary tract, unspecified
0.000 0.977 0.023
N22 Calculus of urinary tract in diseases classified elsewhere
0.000 0.977 0.023
I08.0 Disorders of both mitral and aortic valves
0.000 0.978 0.022
I27 Other pulmonary heart diseases
0.000 0.978 0.022
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.978 0.022
I49.4 Other and unspecified premature depolarisation
0.000 0.979 0.021
N20.2 Calculus of kidney with calculus of ureter
0.000 0.979 0.021
I37 Pulmonary valve disorders
0.000 0.979 0.021
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.979 0.021
I95.2 Hypotension due to drugs
0.000 0.979 0.021
Q61.3 Polycystic kidney, unspecified
0.020 0.980 0.000
I49.0 Ventricular fibrillation and flutter
0.000 0.980 0.020
I52 Other heart disorders in diseases classified elsewhere
0.000 0.980 0.020
I48 Atrial fibrillation and flutter
0.000 0.980 0.020
I41 Myocarditis in diseases classified elsewhere
0.000 0.980 0.020
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.980 0.020
I32 Pericarditis in diseases classified elsewhere
0.000 0.980 0.020
I40 Acute myocarditis
0.000 0.980 0.020
Q61.2 Polycystic kidney, adult type
0.020 0.980 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.980 0.020
M05.9 Seropositive rheumatoid arthritis, unspecified
0.020 0.980 0.000
Q61 Cystic kidney disease
0.020 0.980 0.000
I30 Acute pericarditis
0.000 0.980 0.020
I50.0 Congestive heart failure
0.000 0.980 0.020
I49.2 Junctional premature depolarisation
0.000 0.981 0.019
I49.3 Ventricular premature depolarisation
0.000 0.981 0.019
I36 Nonrheumatic tricuspid valve disorders
0.000 0.982 0.018
N21.8 Other lower urinary tract calculus
0.000 0.982 0.018
E78.8 Other disorders of lipoprotein metabolism
0.000 0.982 0.018
N87.9 Dysplasia of cervix uteri, unspecified
0.017 0.983 0.000
Q61.9 Cystic kidney disease, unspecified
0.017 0.983 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.017 0.983 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.983 0.017
I46.9 Cardiac arrest, unspecified
0.000 0.983 0.017
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.017 0.983 0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere
0.000 0.983 0.016
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]
0.000 0.983 0.016
I46.1 Sudden cardiac death, so described
0.000 0.983 0.016
M95.0 Acquired deformity of nose
0.016 0.984 0.000
N32.8 Other specified disorders of bladder
0.000 0.984 0.016
I12.0 Hypertensive renal disease with renal failure
0.000 0.984 0.016
I95.1 Orthostatic hypotension
0.000 0.984 0.016
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.016 0.984 0.000
I27.1 Kyphoscoliotic heart disease
0.000 0.984 0.016
I47 Paroxysmal tachycardia
0.000 0.984 0.016
E78.1 Pure hyperglyceridaemia
0.000 0.984 0.016
M96.8 Other postprocedural musculoskeletal disorders
0.016 0.984 0.000
I37.0 Pulmonary valve stenosis
0.000 0.984 0.015
I37.1 Pulmonary valve insufficiency
0.000 0.985 0.015
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.015 0.985 0.000
I37.9 Pulmonary valve disorder, unspecified
0.000 0.985 0.015
I37.8 Other pulmonary valve disorders
0.000 0.985 0.015
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.985 0.015
I33 Acute and subacute endocarditis
0.001 0.985 0.015
E78.3 Hyperchylomicronaemia
0.000 0.985 0.015
I30.1 Infective pericarditis
0.000 0.985 0.015
Q61.0 Congenital single renal cyst
0.015 0.985 0.000
S91.3 Open wound of other parts of foot
0.000 0.985 0.015
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.015 0.985 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.985 0.015
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.985 0.015
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.985 0.015
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.985 0.015
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.985 0.015
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.985 0.015
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.985 0.015
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.985 0.015
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.985 0.015
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.985 0.015
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.985 0.015
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.985 0.015
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.985 0.015
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.985 0.015
I48.4 Atypical atrial flutter
0.000 0.985 0.015
I48.3 Typical atrial flutter
0.000 0.985 0.015
I48.2 Chronic atrial fibrillation
0.000 0.985 0.015
I48.1 Persistent atrial fibrillation
0.000 0.985 0.015
I48.0 Paroxysmal atrial fibrillation
0.000 0.985 0.015
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.985 0.015
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.985 0.015
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.985 0.015
E78.6 Lipoprotein deficiency
0.000 0.985 0.015
I40.9 Acute myocarditis, unspecified
0.000 0.985 0.015
I40.8 Other acute myocarditis
0.000 0.985 0.015
I40.1 Isolated myocarditis
0.000 0.985 0.015
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.985 0.014
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.985 0.014
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.985 0.014
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.014 0.985 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.014 0.985 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.014 0.985 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.014 0.985 0.000
I40.0 Infective myocarditis
0.000 0.985 0.014
Q61.8 Other cystic kidney diseases
0.014 0.985 0.000
Q61.1 Polycystic kidney, infantile type
0.014 0.985 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.986 0.014
J47 Bronchiectasis
0.014 0.986 0.000
I30.8 Other forms of acute pericarditis
0.000 0.986 0.014
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.986 0.014
M96.0 Pseudarthrosis after fusion or arthrodesis
0.014 0.986 0.000
Q61.4 Renal dysplasia
0.014 0.986 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.014 0.986 0.000
K31.8 Other specified diseases of stomach and duodenum
0.014 0.986 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.014 0.986 0.000
Q61.5 Medullary cystic kidney
0.014 0.986 0.000
I31 Other diseases of pericardium
0.000 0.986 0.014
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.014 0.986 0.000
S91 Open wound of ankle and foot
0.000 0.987 0.013
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.987 0.013
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.987 0.013
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.987 0.013
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.987 0.013
S92 Fracture of foot, except ankle
0.000 0.987 0.013
I30.9 Acute pericarditis, unspecified
0.000 0.987 0.013
S92.30 Fracture of metatarsal bone (closed)
0.000 0.987 0.013
S92.3 Fracture of metatarsal bone
0.000 0.987 0.013
I47.0 Reentry ventricular arrhythmia
0.000 0.987 0.013
E78.4 Other hyperlipidaemia
0.000 0.988 0.012
S90-S99 Injuries to the ankle and foot
0.000 0.988 0.012
S92.4 Fracture of great toe
0.000 0.988 0.012
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.988 0.012
I33.9 Acute endocarditis, unspecified
0.000 0.988 0.012
M95.1 Cauliflower ear
0.012 0.988 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.012 0.988 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.012 0.988 0.000
K31 Other diseases of stomach and duodenum
0.012 0.988 0.000
I49.5 Sick sinus syndrome
0.000 0.989 0.011
S92.1 Fracture of talus
0.000 0.989 0.011
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.989 0.011
K31.1 Adult hypertrophic pyloric stenosis
0.011 0.989 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.011 0.989 0.000
M96.5 Postradiation scoliosis
0.011 0.989 0.000
M96.4 Postsurgical lordosis
0.011 0.989 0.000
M96.3 Postlaminectomy kyphosis
0.011 0.989 0.000
M96.2 Postradiation kyphosis
0.011 0.989 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.000 0.989 0.011
M05 Seropositive rheumatoid arthritis
0.011 0.989 0.000
I31.9 Disease of pericardium, unspecified
0.000 0.989 0.011
S92.41 Fracture of great toe (open)
0.000 0.989 0.011
I51.8 Other ill-defined heart diseases
0.000 0.989 0.011
S91.1 Open wound of toe(s) without damage to nail
0.000 0.989 0.011
M99 Biomechanical lesions, not elsewhere classified
0.011 0.989 0.000
I31.0 Chronic adhesive pericarditis
0.000 0.989 0.011
I27.9 Pulmonary heart disease, unspecified
0.000 0.989 0.010
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.010 0.989 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.010 0.989 0.000
M95.5 Acquired deformity of pelvis
0.010 0.989 0.000
I31.8 Other specified diseases of pericardium
0.000 0.990 0.010
I31.2 Haemopericardium, not elsewhere classified
0.000 0.990 0.010
I51 Complications and ill-defined descriptions of heart disease
0.000 0.990 0.010
I47.1 Supraventricular tachycardia
0.000 0.990 0.010
S92.2 Fracture of other tarsal bone(s)
0.000 0.990 0.010
S93.1 Dislocation of toe(s)
0.000 0.990 0.010
S92.10 Fracture of talus (closed)
0.000 0.990 0.010
S92.40 Fracture of great toe (closed)
0.000 0.990 0.010
S92.5 Fracture of other toe
0.000 0.990 0.010
K31.7 Polyp of stomach and duodenum
0.010 0.990 0.000
S91.0 Open wound of ankle
0.000 0.990 0.010
S91.7 Multiple open wounds of ankle and foot
0.000 0.990 0.010
M95.3 Acquired deformity of neck
0.010 0.990 0.000
S99 Other and unspecified injuries of ankle and foot
0.000 0.990 0.010
Q60-Q64 Congenital malformations of the urinary system
0.010 0.990 0.000
I47.2 Ventricular tachycardia
0.000 0.990 0.010
M95.2 Other acquired deformity of head
0.010 0.990 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.010 0.990 0.000
S92.9 Fracture of foot, unspecified
0.000 0.990 0.010
I31.1 Chronic constrictive pericarditis
0.000 0.990 0.009
K31.6 Fistula of stomach and duodenum
0.010 0.990 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.000 0.990 0.010
S92.31 Fracture of metatarsal bone (open)
0.000 0.991 0.009
I38 Endocarditis, valve unspecified
0.000 0.991 0.009
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.991 0.009
J92.0 Pleural plaque with presence of asbestos
0.000 0.991 0.009
S92.7 Multiple fractures of foot
0.000 0.991 0.009
E78.2 Mixed hyperlipidaemia
0.000 0.991 0.009
S91.2 Open wound of toe(s) with damage to nail
0.000 0.991 0.009
S98 Traumatic amputation of ankle and foot
0.000 0.991 0.009
S95 Injury of blood vessels at ankle and foot level
0.000 0.991 0.009
S94 Injury of nerves at ankle and foot level
0.000 0.991 0.009
K31.3 Pylorospasm, not elsewhere classified
0.009 0.991 0.000
S99.9 Unspecified injury of ankle and foot
0.000 0.991 0.009
M05.2 Rheumatoid vasculitis
0.009 0.991 0.000
M05.1 Rheumatoid lung disease
0.009 0.991 0.000
S92.50 Fracture of other toe (closed)
0.000 0.991 0.009
M99.8 Other biomechanical lesions
0.008 0.991 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.008 0.991 0.000
K31.0 Acute dilatation of stomach
0.008 0.991 0.000
K31.4 Gastric diverticulum
0.009 0.991 0.000
M95.4 Acquired deformity of chest and rib
0.008 0.991 0.000
S97 Crushing injury of ankle and foot
0.000 0.991 0.008
I51.0 Cardiac septal defect, acquired
0.000 0.992 0.008
S92.11 Fracture of talus (open)
0.000 0.992 0.008
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)
0.008 0.992 0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate
0.008 0.992 0.000
S93.4 Sprain and strain of ankle
0.000 0.992 0.008
S93.6 Sprain and strain of other and unspecified parts of foot
0.000 0.992 0.008
S93.5 Sprain and strain of toe(s)
0.000 0.992 0.008
S93.2 Rupture of ligaments at ankle and foot level
0.000 0.992 0.008
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.008 0.992 0.000
M05.0 Felty's syndrome
0.008 0.992 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.992 0.008
K31.5 Obstruction of duodenum
0.008 0.992 0.000
M05.8 Other seropositive rheumatoid arthritis
0.008 0.992 0.000
S93.0 Dislocation of ankle joint
0.000 0.992 0.008
M99.5 Intervertebral disk stenosis of neural canal
0.008 0.992 0.000
M99.9 Biomechanical lesion, unspecified
0.008 0.992 0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina
0.008 0.992 0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina
0.008 0.992 0.000
M99.4 Connective tissue stenosis of neural canal
0.008 0.992 0.000
M99.3 Osseous stenosis of neural canal
0.008 0.992 0.000
M99.2 Subluxation stenosis of neural canal
0.008 0.992 0.000
M99.1 Subluxation complex (vertebral)
0.008 0.992 0.000
M99.0 Segmental and somatic dysfunction
0.008 0.992 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.008 0.992 0.000
S92.20 Fracture of other tarsal bone(s) (closed)
0.000 0.992 0.008
M95.96 Acquired deformity of musculoskeletal system, unspecified
0.008 0.992 0.000
I51.5 Myocardial degeneration
0.000 0.992 0.008
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.992 0.008
Q64 Other congenital malformations of urinary system
0.008 0.992 0.000
S92.21 Fracture of other tarsal bone(s) (open)
0.000 0.992 0.007
S99.7 Multiple injuries of ankle and foot
0.000 0.993 0.007
S90 Superficial injury of ankle and foot
0.000 0.993 0.007
M05.20 Rheumatoid vasculitis (Multiple sites)
0.007 0.993 0.000
S92.91 Fracture of foot, unspecified (open)
0.000 0.993 0.007
S92.90 Fracture of foot, unspecified (closed)
0.000 0.993 0.007
S96 Injury of muscle and tendon at ankle and foot level
0.000 0.993 0.007
J44 Other chronic obstructive pulmonary disease
0.007 0.993 0.000
M99.83 Other biomechanical lesions (Lumbar region)
0.007 0.993 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.993 0.007
M05.19 Rheumatoid lung disease (Site unspecified)
0.007 0.993 0.000
S92.71 Multiple fractures of foot (open)
0.000 0.993 0.007
S92.0 Fracture of calcaneus
0.000 0.993 0.007
S94.9 Injury of unspecified nerve at ankle and foot level
0.000 0.993 0.007
S94.8 Injury of other nerves at ankle and foot level
0.000 0.993 0.007
S94.7 Injury of multiple nerves at ankle and foot level
0.000 0.993 0.007
S94.3 Injury of cutaneous sensory nerve at ankle and foot level
0.000 0.993 0.007
S94.2 Injury of deep peroneal nerve at ankle and foot level
0.000 0.993 0.007
S94.1 Injury of medial plantar nerve
0.000 0.993 0.007
S94.0 Injury of lateral plantar nerve
0.000 0.993 0.007
S95.9 Injury of unspecified blood vessel at ankle and foot level
0.000 0.993 0.007
S95.8 Injury of other blood vessels at ankle and foot level
0.000 0.993 0.007
S95.7 Injury of multiple blood vessels at ankle and foot level
0.000 0.993 0.007
S95.2 Injury of dorsal vein of foot
0.000 0.993 0.007
S95.1 Injury of plantar artery of foot
0.000 0.993 0.007
S95.0 Injury of dorsal artery of foot
0.000 0.993 0.007
S98.4 Traumatic amputation of foot, level unspecified
0.000 0.993 0.007
S98.3 Traumatic amputation of other parts of foot
0.000 0.993 0.007
S98.2 Traumatic amputation of two or more toes
0.000 0.993 0.007
S98.1 Traumatic amputation of one toe
0.000 0.993 0.007
S98.0 Traumatic amputation of foot at ankle level
0.000 0.993 0.007
M05.29 Rheumatoid vasculitis (Site unspecified)
0.006 0.993 0.000
M05.28 Rheumatoid vasculitis (Other)
0.006 0.993 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.006 0.993 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.006 0.993 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.006 0.993 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.006 0.993 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.006 0.993 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.006 0.993 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.006 0.993 0.000
Q62.5 Duplication of ureter
0.006 0.993 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.006 0.993 0.000
J38.7 Other diseases of larynx
0.007 0.993 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.993 0.006
M05.18 Rheumatoid lung disease (Other)
0.006 0.993 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.006 0.993 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.006 0.993 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.006 0.993 0.000
M05.14 Rheumatoid lung disease (Hand)
0.006 0.993 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.006 0.993 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.006 0.993 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.006 0.993 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.006 0.993 0.000
I50.9 Heart failure, unspecified
0.000 0.994 0.006
M99.89 Other biomechanical lesions (Abdomen and other)
0.006 0.994 0.000
M99.88 Other biomechanical lesions (Rib cage)
0.006 0.994 0.000
M99.87 Other biomechanical lesions (Upper extremity)
0.006 0.994 0.000
M99.86 Other biomechanical lesions (Lower extremity)
0.006 0.994 0.000
M99.85 Other biomechanical lesions (Pelvic region)
0.006 0.994 0.000
M99.84 Other biomechanical lesions (Sacral region)
0.006 0.994 0.000
M99.82 Other biomechanical lesions (Thoracic region)
0.006 0.994 0.000
M99.81 Other biomechanical lesions (Cervical region)
0.006 0.994 0.000
M99.80 Other biomechanical lesions (Head region)
0.006 0.994 0.000
G93.9 Disorder of brain, unspecified
0.006 0.994 0.000
S97.1 Crushing injury of toe(s)
0.000 0.994 0.006
S97.0 Crushing injury of ankle
0.000 0.994 0.006
Q63 Other congenital malformations of kidney
0.006 0.994 0.000
S92.70 Multiple fractures of foot (closed)
0.000 0.994 0.006
M05.09 Felty's syndrome (Site unspecified)
0.006 0.994 0.000
M05.08 Felty's syndrome (Other)
0.006 0.994 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.006 0.994 0.000
M05.06 Felty's syndrome (Lower leg)
0.006 0.994 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.006 0.994 0.000
M05.04 Felty's syndrome (Hand)
0.006 0.994 0.000
M05.03 Felty's syndrome (Forearm)
0.006 0.994 0.000
M05.02 Felty's syndrome (Upper arm)
0.006 0.994 0.000
M05.01 Felty's syndrome (Shoulder region)
0.006 0.994 0.000
M05.00 Felty's syndrome (Multiple sites)
0.006 0.994 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.006 0.994 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.006 0.994 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.006 0.994 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.006 0.994 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.006 0.994 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.006 0.994 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.006 0.994 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.006 0.994 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.006 0.994 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.006 0.994 0.000
S93.40 Sprain of unspecified ligament of ankle
0.000 0.994 0.006
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)
0.006 0.994 0.000
S92.51 Fracture of other toe (open)
0.000 0.994 0.006
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.006 0.994 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.006 0.994 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.006 0.994 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.006 0.994 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.006 0.994 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.006 0.994 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.006 0.994 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.006 0.994 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.006 0.994 0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck
0.006 0.994 0.000
M99.59 Intervertebral disc stenosis of neural canal-Abdomen/other
0.006 0.994 0.000
M99.58 Intervertebral disc stenosis of neural canal-Rib cage
0.006 0.994 0.000
M99.57 Intervertebral disc stenosis of neural canal-Upper extremit
0.006 0.994 0.000
M99.56 Intervertebral disc stenosis of neural canal-Lower extremit
0.006 0.994 0.000
M99.55 Intervertebral disc stenosis of neural canal (Pelvic region)
0.006 0.994 0.000
M99.54 Intervertebral disc stenosis of neural canal (Sacral region)
0.006 0.994 0.000
M99.52 Intervertebral disc stenosis of neural canal (Thoracic region)
0.006 0.994 0.000
M99.51 Intervertebral disc stenosis of neural canal (Cervical region)
0.006 0.994 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.006 0.994 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.006 0.994 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.994 0.006
T42.4 Benzodiazepines
0.006 0.994 0.000
M99.09 Segmental and somatic dysfunction (Abdomen and other)
0.006 0.994 0.000
M99.08 Segmental and somatic dysfunction (Rib cage)
0.006 0.994 0.000
M99.07 Segmental and somatic dysfunction (Upper extremity)
0.006 0.994 0.000
M99.06 Segmental and somatic dysfunction (Lower extremity)
0.006 0.994 0.000
M99.05 Segmental and somatic dysfunction (Pelvic region)
0.006 0.994 0.000
M99.04 Segmental and somatic dysfunction (Sacral region)
0.006 0.994 0.000
M99.03 Segmental and somatic dysfunction (Lumbar region)
0.006 0.994 0.000
M99.02 Segmental and somatic dysfunction (Thoracic region)
0.006 0.994 0.000
M99.01 Segmental and somatic dysfunction (Cervical region)
0.006 0.994 0.000
M99.00 Segmental and somatic dysfunction (Head region)
0.006 0.994 0.000
M99.19 Subluxation complex (vertebral) (Abdomen and other)
0.006 0.994 0.000
M99.18 Subluxation complex (vertebral) (Rib cage)
0.006 0.994 0.000
M99.17 Subluxation complex (vertebral) (Upper extremity)
0.006 0.994 0.000
M99.16 Subluxation complex (vertebral) (Lower extremity)
0.006 0.994 0.000
M99.15 Subluxation complex (vertebral) (Pelvic region)
0.006 0.994 0.000
M99.14 Subluxation complex (vertebral) (Sacral region)
0.006 0.994 0.000
M99.13 Subluxation complex (vertebral) (Lumbar region)
0.006 0.994 0.000
M99.12 Subluxation complex (vertebral) (Thoracic region)
0.006 0.994 0.000
M99.11 Subluxation complex (vertebral) (Cervical region)
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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