TreeWAS – Variant ID: rs12579720

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.993	0.007	0.000
I25.1 Atherosclerotic heart disease	0.955	0.045	0.000
I25 Chronic ischaemic heart disease	0.940	0.060	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.906	0.094	0.000
I25.5 Ischaemic cardiomyopathy	0.889	0.111	0.000
I25.2 Old myocardial infarction	0.821	0.179	0.000
I25.4 Coronary artery aneurysm	0.808	0.192	0.000
I25.3 Aneurysm of heart	0.690	0.310	0.000
I25.6 Silent myocardial ischaemia	0.690	0.310	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.440	0.560	0.000
I20-I25 Ischaemic heart diseases	0.388	0.612	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.380	0.619	0.001
I20 Angina pectoris	0.304	0.696	0.000
I23 Certain current complications following acute myocardial infarction	0.296	0.704	0.000
I20.8 Other forms of angina pectoris	0.292	0.708	0.000
I21 Acute myocardial infarction	0.282	0.718	0.000
I10-I15 Hypertensive diseases	0.279	0.721	0.000
I22 Subsequent myocardial infarction	0.255	0.745	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.240	0.760	0.000
I20.1 Angina pectoris with documented spasm	0.236	0.764	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.236	0.764	0.000
I23.8 Other current complications following acute myocardial infarction	0.230	0.770	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.224	0.776	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.212	0.788	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.212	0.788	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.212	0.788	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.212	0.788	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.212	0.788	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.212	0.788	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.212	0.788	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.205	0.795	0.000
I13 Hypertensive heart and renal disease	0.205	0.795	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.202	0.798	0.000
I21.4 Acute subendocardial myocardial infarction	0.198	0.802	0.000
I24 Other acute ischaemic heart diseases	0.194	0.806	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.194	0.806	0.000
I22.8 Subsequent myocardial infarction of other sites	0.184	0.816	0.000
I11 Hypertensive heart disease	0.178	0.822	0.000
I12 Hypertensive renal disease	0.175	0.825	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.160	0.840	0.000
I24.8 Other forms of acute ischaemic heart disease	0.157	0.843	0.000
I12.9 Hypertensive renal disease without renal failure	0.151	0.849	0.000
I24.1 Dressler's syndrome	0.148	0.852	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.147	0.853	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.147	0.853	0.000
I20.9 Angina pectoris, unspecified	0.146	0.854	0.000
I15 Secondary hypertension	0.144	0.856	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.141	0.859	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.139	0.860	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.136	0.864	0.000
I15.8 Other secondary hypertension	0.098	0.902	0.000
I15.2 Hypertension secondary to endocrine disorders	0.098	0.902	0.000
I15.9 Seconday hypertension, unspecified	0.096	0.904	0.000
I21.9 Acute myocardial infarction, unspecified	0.096	0.904	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.096	0.904	0.000
I15.1 Hypertension secondary to other renal disorders	0.094	0.906	0.000
Chapter IX Diseases of the circulatory system	0.093	0.907	0.000
I15.0 Renovascular hypertension	0.092	0.907	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.092	0.908	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.082	0.918	0.000
I00-I02 Acute rheumatic fever	0.068	0.932	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.060	0.940	0.000
I00 Rheumatic fever without mention of heart involvement	0.050	0.950	0.000
I02 Rheumatic chorea	0.049	0.951	0.000
I01 Rheumatic fever with heart involvement	0.049	0.951	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.041	0.958	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.035	0.965	0.000
I01.8 Other acute rheumatic heart disease	0.035	0.965	0.000
I01.2 Acute rheumatic myocarditis	0.035	0.965	0.000
I01.1 Acute rheumatic endocarditis	0.035	0.965	0.000
I01.0 Acute rheumatic pericarditis	0.035	0.965	0.000
I02.9 Rheumatic chorea without heart involvement	0.035	0.965	0.000
I02.0 Rheumatic chorea with heart involvement	0.035	0.965	0.000
I28 Other diseases of pulmonary vessels	0.032	0.968	0.000
C78.7 Secondary malignant neoplasm of liver	0.030	0.970	0.000
I28.8 Other specified diseases of pulmonary vessels	0.027	0.972	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.975	0.025
I28.1 Aneurysm of pulmonary artery	0.023	0.977	0.000
I12.0 Hypertensive renal disease with renal failure	0.023	0.977	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.022	0.977	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.022	0.978	0.000
I27 Other pulmonary heart diseases	0.021	0.979	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.020	0.979	0.000
I20.0 Unstable angina	0.019	0.981	0.000
C44.0 Skin of lip	0.000	0.982	0.018
I27.9 Pulmonary heart disease, unspecified	0.017	0.983	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.016	0.984	0.000
I27.1 Kyphoscoliotic heart disease	0.015	0.984	0.000
I26 Pulmonary embolism	0.015	0.985	0.000
I27.8 Other specified pulmonary heart diseases	0.015	0.985	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.015	0.985	0.000
I27.0 Primary pulmonary hypertension	0.015	0.985	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.015	0.985	0.000
C20 Malignant neoplasm of rectum	0.013	0.987	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.013	0.987	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.013	0.987	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.013	0.987	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.012	0.988	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
I98.0 Cardiovascular syphilis	0.012	0.988	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.012	0.988	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.012	0.988	0.000
N43.3 Hydrocele, unspecified	0.000	0.988	0.012
C78.0 Secondary malignant neoplasm of lung	0.012	0.988	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.012	0.988	0.000
I97.1 Other functional disturbances following cardiac surgery	0.011	0.989	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.010	0.990	0.000
I97.0 Postcardiotomy syndrome	0.010	0.990	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.010	0.990	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.010	0.990	0.000
I05-I09 Chronic rheumatic heart diseases	0.009	0.990	0.000
N48.0 Leukoplakia of penis	0.000	0.991	0.009
N48 Other disorders of penis	0.000	0.991	0.009
N48.2 Other inflammatory disorders of penis	0.000	0.991	0.009
I97.2 Postmastectomy lymphoedema syndrome	0.008	0.991	0.000
C78.2 Secondary malignant neoplasm of pleura	0.008	0.992	0.000
C81.9 Hodgkin's disease, unspecified	0.008	0.992	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.008	0.992	0.000
Z74.0 Reduced mobility	0.008	0.992	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.007	0.992	0.000
I27.2 Other secondary pulmonary hypertension	0.007	0.993	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.993	0.007
N48.3 Priapism	0.000	0.993	0.007
N48.9 Disorder of penis, unspecified	0.000	0.993	0.007
O70.0 First degree perineal laceration during delivery	0.007	0.993	0.000
H18.4 Corneal degeneration	0.007	0.993	0.000
I06 Rheumatic aortic valve diseases	0.006	0.993	0.001
I85.9 Oesophageal varices without bleeding	0.006	0.994	0.000
I09 Other rheumatic heart diseases	0.006	0.994	0.001
I99 Other and unspecified disorders of circulatory system	0.006	0.994	0.001
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.006	0.994	0.000
N48.5 Ulcer of penis	0.000	0.994	0.006
H18.8 Other specified disorders of cornea	0.006	0.994	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.006	0.994	0.000
C02.9 Tongue, unspecified	0.006	0.994	0.000
H18 Other disorders of cornea	0.005	0.995	0.000
N43 Hydrocele and spermatocele	0.000	0.995	0.005
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.005	0.995	0.000
J32.0 Chronic maxillary sinusitis	0.005	0.995	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.005	0.995	0.000
N02.8 Other	0.000	0.995	0.005
I06.9 Rheumatic aortic valve disease, unspecified	0.005	0.995	0.000
I06.8 Other rheumatic aortic valve diseases	0.005	0.995	0.001
I06.0 Rheumatic aortic stenosis	0.005	0.995	0.000
I07 Rheumatic tricuspid valve diseases	0.004	0.995	0.001
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.005	0.995	0.000
H18.6 Keratoconus	0.005	0.995	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.005	0.995	0.000
I85 Oesophageal varices	0.005	0.995	0.000
H18.5 Hereditary corneal dystrophies	0.005	0.995	0.000
I09.8 Other specified rheumatic heart diseases	0.004	0.995	0.001
I09.2 Chronic rheumatic pericarditis	0.004	0.995	0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.004	0.995	0.001
I09.0 Rheumatic myocarditis	0.004	0.995	0.001
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.995	0.005
C79 Secondary malignant neoplasm of other sites	0.005	0.995	0.000
M07.3 Other psoriatic arthropathies	0.005	0.995	0.000
C02.1 Border of tongue	0.004	0.995	0.000
N43.2 Other hydrocele	0.000	0.995	0.004
N48.4 Impotence of organic origin	0.000	0.995	0.004
S02.2 Fracture of nasal bones	0.000	0.995	0.004
I06.1 Rheumatic aortic insufficiency	0.004	0.996	0.001
C02.3 Anterior two-thirds of tongue, part unspecified	0.004	0.996	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.004	0.996	0.000
C02.4 Lingual tonsil	0.004	0.996	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.004	0.996	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.004	0.996	0.000
H18.9 Disorder of cornea, unspecified	0.004	0.996	0.000
N43.0 Encysted hydrocele	0.000	0.996	0.004
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.004	0.996	0.000
C79.2 Secondary malignant neoplasm of skin	0.004	0.996	0.000
N48.1 Balanoposthitis	0.000	0.996	0.004
I89.1 Lymphangitis	0.004	0.996	0.000
N43.4 Spermatocele	0.000	0.996	0.004
C76 Malignant neoplasm of other and ill-defined sites	0.004	0.996	0.000
C02.8 Overlapping lesion of tongue	0.004	0.996	0.000
C02.0 Dorsal surface of tongue	0.004	0.996	0.000
H18.7 Other corneal deformities	0.004	0.996	0.000
I09.9 Rheumatic heart disease, unspecified	0.003	0.996	0.001
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.004	0.996	0.000
N43.1 Infected hydrocele	0.000	0.996	0.004
C08 Malignant neoplasm of other and unspecified major salivary glands	0.004	0.996	0.000
C02.2 Ventral surface of tongue	0.004	0.996	0.000
I07.9 Tricuspid valve disease, unspecified	0.003	0.996	0.001
I07.8 Other tricuspid valve diseases	0.003	0.996	0.001
I07.2 Tricuspid stenosis with insufficiency	0.003	0.996	0.001
I07.0 Tricuspid stenosis	0.003	0.996	0.001
L40.5 Arthropathic psoriasis	0.004	0.996	0.000
C79.6 Secondary malignant neoplasm of ovary	0.004	0.996	0.000
C11 Malignant neoplasm of nasopharynx	0.004	0.996	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.004	0.996	0.000
H18.1 Bullous keratopathy	0.004	0.996	0.000
C04 Malignant neoplasm of floor of mouth	0.004	0.996	0.000
C09 Malignant neoplasm of tonsil	0.004	0.996	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.996	0.004
M07.38 Other psoriatic arthropathies (Other)	0.004	0.996	0.000
C00 Malignant neoplasm of lip	0.004	0.996	0.000
Z74 Problems related to care-provider dependency	0.004	0.996	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.004	0.996	0.000
C08.0 Submandibular gland	0.004	0.996	0.000
H18.3 Changes in corneal membranes	0.003	0.996	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.003	0.996	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.003	0.996	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.003	0.996	0.000
L43.9 Lichen planus, unspecified	0.004	0.996	0.000
C80 Malignant neoplasm without specification of site	0.004	0.996	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.003	0.996	0.000
C01 Malignant neoplasm of base of tongue	0.003	0.996	0.000
C76.3 Pelvis	0.003	0.997	0.000
N48.8 Other specified disorders of penis	0.000	0.997	0.003
C11.9 Nasopharynx, unspecified	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.003	0.997	0.000
C12 Malignant neoplasm of pyriform sinus	0.003	0.997	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.003	0.997	0.000
C76.0 Head, face and neck	0.003	0.997	0.000
C05 Malignant neoplasm of palate	0.003	0.997	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.997	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.997	0.003
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
C09.9 Tonsil, unspecified	0.003	0.997	0.000
C08.9 Major salivary gland, unspecified	0.003	0.997	0.000
I49.3 Ventricular premature depolarisation	0.003	0.997	0.000
C07 Malignant neoplasm of parotid gland	0.003	0.997	0.000
C13 Malignant neoplasm of hypopharynx	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
Z63.0 Problems in relationship with spouse or partner	0.000	0.997	0.003
C04.9 Floor of mouth, unspecified	0.003	0.997	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.003	0.997	0.000
C76.7 Other ill-defined sites	0.003	0.997	0.000
C76.5 Lower limb	0.003	0.997	0.000
C76.4 Upper limb	0.003	0.997	0.000
C10 Malignant neoplasm of oropharynx	0.003	0.997	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.003	0.997	0.000
I81 Portal vein thrombosis	0.003	0.997	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.003	0.997	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.003	0.997	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.003	0.997	0.000
C08.8 Overlapping lesion of major salivary glands	0.003	0.997	0.000
C08.1 Sublingual gland	0.003	0.997	0.000
C09.0 Tonsillar fossa	0.003	0.997	0.000
C76.1 Thorax	0.003	0.997	0.000
I85.0 Oesophageal varices with bleeding	0.003	0.997	0.000
Z74.1 Need for assistance with personal care	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.003	0.997	0.000
C03 Malignant neoplasm of gum	0.003	0.997	0.000
C76.2 Abdomen	0.003	0.997	0.000
C00.9 Lip, unspecified	0.003	0.997	0.000
C11.1 Posterior wall of nasopharynx	0.003	0.997	0.000
C11.8 Overlapping lesion of nasopharynx	0.003	0.997	0.000
C11.3 Anterior wall of nasopharynx	0.003	0.997	0.000
C11.2 Lateral wall of nasopharynx	0.003	0.997	0.000
C11.0 Superior wall of nasopharynx	0.003	0.997	0.000
O69.8 Labour and delivery complicated by other cord complications	0.000	0.997	0.003
C00.1 External lower lip	0.003	0.997	0.000
C04.0 Anterior floor of mouth	0.003	0.997	0.000
C06.0 Cheek mucosa	0.003	0.997	0.000
J32 Chronic sinusitis	0.003	0.997	0.000
C05.1 Soft palate	0.003	0.997	0.000
W07.0 Home	0.003	0.997	0.000
I05 Rheumatic mitral valve diseases	0.002	0.997	0.001
C04.8 Overlapping lesion of floor of mouth	0.003	0.997	0.000
C04.1 Lateral floor of mouth	0.003	0.997	0.000
Z74.3 Need for continuous supervision	0.003	0.997	0.000
I88 Nonspecific lymphadenitis	0.003	0.997	0.000
C09.8 Overlapping lesion of tonsil	0.003	0.997	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.003	0.997	0.000
C00.0 External upper lip	0.003	0.997	0.000
C00.8 Overlapping lesion of lip	0.003	0.997	0.000
C00.6 Commissure of lip	0.003	0.997	0.000
C00.5 Lip, unspecified, inner aspect	0.003	0.997	0.000
C00.4 Lower lip, inner aspect	0.003	0.997	0.000
C00.3 Upper lip, inner aspect	0.003	0.997	0.000
C00.2 External lip, unspecified	0.003	0.997	0.000
C14.0 Pharynx, unspecified	0.003	0.997	0.000
Z63.8 Other specified problems related to primary support group	0.000	0.997	0.003
Z63.7 Other stressful life events affecting family and household	0.000	0.997	0.003
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
Z63 Other problems related to primary support group, including family circumstances	0.000	0.997	0.003
L05.0 Pilonidal cyst with abscess	0.000	0.997	0.003
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.003	0.997	0.000
C14.2 Waldeyer's ring	0.003	0.997	0.000
S06.5 Traumatic subdural haemorrhage	0.003	0.997	0.000
G80 Infantile cerebral palsy	0.000	0.997	0.003
J32.2 Chronic ethmoidal sinusitis	0.003	0.997	0.000
J32.1 Chronic frontal sinusitis	0.003	0.997	0.000
F06.7 Mild cognitive disorder	0.000	0.997	0.003
Z74.2 Need for assistance at home and no other household member able to render care	0.003	0.997	0.000
M22.8 Other disorders of patella	0.000	0.997	0.003
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.997	0.003
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.003	0.997	0.000
C06.1 Vestibule of mouth	0.003	0.997	0.000
C05.8 Overlapping lesion of palate	0.002	0.997	0.000
C05.2 Uvula	0.002	0.997	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.003	0.997	0.000
C03.9 Gum, unspecified	0.002	0.997	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.002	0.997	0.000
C13.9 Hypopharynx, unspecified	0.002	0.997	0.000
G80.1 Spastic diplegia	0.000	0.997	0.003
I88.0 Nonspecific mesenteric lymphadenitis	0.002	0.997	0.000
C13.8 Overlapping lesion of hypopharynx	0.002	0.997	0.000
C13.2 Posterior wall of hypopharynx	0.002	0.997	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.002	0.997	0.000
L40 Psoriasis	0.003	0.997	0.000
C10.8 Overlapping lesion of oropharynx	0.002	0.997	0.000
C10.4 Branchial cleft	0.002	0.997	0.000
C10.3 Posterior wall of oropharynx	0.002	0.997	0.000
C10.2 Lateral wall of oropharynx	0.002	0.997	0.000
C10.1 Anterior surface of epiglottis	0.002	0.997	0.000
C10.0 Vallecula	0.002	0.997	0.000
C81 Hodgkin's disease	0.003	0.997	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.997	0.003
C05.9 Palate, unspecified	0.002	0.997	0.000
C06.9 Mouth, unspecified	0.002	0.997	0.000
J32.3 Chronic sphenoidal sinusitis	0.002	0.997	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.003	0.997	0.000
E78.0 Pure hypercholesterolaemia	0.003	0.997	0.000
J32.8 Other chronic sinusitis	0.002	0.997	0.000
W07.9 Unspecified place	0.002	0.997	0.000
C06.2 Retromolar area	0.002	0.998	0.000
R47.0 Dysphasia and aphasia	0.002	0.998	0.000
Z63.6 Dependent relative needing care at home	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.000	0.998	0.002
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
C81.2 Mixed cellularity	0.002	0.998	0.000
W07 Fall involving chair	0.002	0.998	0.000
C05.0 Hard palate	0.002	0.998	0.000
C10.9 Oropharynx, unspecified	0.002	0.998	0.000
C13.0 Postcricoid region	0.002	0.998	0.000
G80.2 Infantile hemiplegia	0.000	0.998	0.002
I88.1 Chronic lymphadenitis, except mesenteric	0.002	0.998	0.000
Z63.4 Disappearance and death of family member	0.000	0.998	0.002
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.001	0.998	0.001
C03.0 Upper gum	0.002	0.998	0.000
G80.0 Spastic cerebral palsy	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.998	0.002
Z63.9 Problem related to primary support group, unspecified	0.000	0.998	0.002
Z63.3 Absence of family member	0.000	0.998	0.002
Z63.2 Inadequate family support	0.000	0.998	0.002
Z63.1 Problems in relationship with parents and in-laws	0.000	0.998	0.002
L40.9 Psoriasis, unspecified	0.002	0.998	0.000
D11.0 Parotid gland	0.002	0.998	0.000
L43 Lichen planus	0.002	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.000	0.998	0.002
G80.3 Dyskinetic cerebral palsy	0.000	0.998	0.002
H47.3 Other disorders of optic disk	0.000	0.998	0.002
I86 Varicose veins of other sites	0.002	0.998	0.000
L40.3 Pustulosis palmaris et plantaris	0.002	0.998	0.000
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
L40.1 Generalised pustular psoriasis	0.002	0.998	0.000
I05.0 Mitral stenosis	0.001	0.998	0.002
K50.9 Crohn's disease, unspecified	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.001	0.998	0.001
I88.8 Other nonspecific lymphadenitis	0.002	0.998	0.000
H02.3 Blepharochalasis	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.001	0.998	0.001
J32.4 Chronic pansinusitis	0.002	0.998	0.000
W07.8 Other specified place	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.000	0.998	0.002
C81.7 Other Hodgkin's disease	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
L40.2 Acrodermatitis continua	0.002	0.998	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.002	0.998	0.000
K50.1 Crohn's disease of large intestine	0.000	0.998	0.002
W07.5 Trade and service area	0.002	0.998	0.000
Z63.5 Disruption of family by separation and divorce	0.000	0.998	0.002
C03.1 Lower gum	0.002	0.998	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.002	0.998	0.000
C81.3 Lymphocytic depletion	0.002	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.002	0.998	0.000
L40.8 Other psoriasis	0.002	0.998	0.000
W07.1 Residential institution	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
D21.2 Connective and other soft tissue of lower limb, including hip	0.002	0.998	0.000
S02.6 Fracture of mandible	0.000	0.998	0.002
L98.0 Pyogenic granuloma	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.000	0.998	0.002
L40.4 Guttate psoriasis	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.998	0.002
I86.3 Vulval varices	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.000	0.998	0.002
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
W07.2 School, other institution and public administrative area	0.002	0.998	0.000
W07.7 Farm	0.002	0.998	0.000
W07.6 Industrial and construction area	0.002	0.998	0.000
W07.4 Street and highway	0.002	0.998	0.000
W07.3 Sports and athletics area	0.002	0.998	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.998	0.002
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
Z74.8 Other problems related to care-provider dependency	0.001	0.998	0.001
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
H53.0 Amblyopia ex anopsia	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.998	0.002
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.998	0.002
L43.3 Subacute (active) lichen planus	0.002	0.998	0.000
L43.2 Lichenoid drug reaction	0.002	0.998	0.000
L43.1 Bullous lichen planus	0.002	0.998	0.000
L43.0 Hypertrophic lichen planus	0.002	0.998	0.000
I86.0 Sublingual varices	0.002	0.998	0.000
M07.6 Other enteropathic arthropathies	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
M07.5 Arthropathy in ulcerative colitis	0.002	0.998	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.002	0.998	0.000
M07.2 Psoriatic spondylitis	0.002	0.998	0.000
M07.1 Arthritis mutilans	0.002	0.998	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.002	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.002
I88.9 Nonspecific lymphadenitis, unspecified	0.002	0.998	0.000
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
I83 Varicose veins of lower extremities	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.000	0.998	0.002
N02 Recurrent and persistent haematuria	0.000	0.998	0.002
M19.92 Arthrosis, unspecified (Upper arm)	0.002	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
I07.1 Tricuspid insufficiency	0.001	0.998	0.001
H73 Other disorders of tympanic membrane	0.000	0.998	0.002
I08 Multiple valve diseases	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.998	0.002
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.002	0.998	0.000
C81.0 Lymphocytic predominance	0.001	0.998	0.000
I86.4 Gastric varices	0.002	0.998	0.000
M22.2 Patellofemoral disorders	0.000	0.998	0.002
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.998	0.002
S02.3 Fracture of orbital floor	0.000	0.998	0.002
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.002
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
G82.3 Flaccid tetraplegia	0.000	0.998	0.002
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
W07.29 Fall involving chair; School, other institution and public administrative area; During unspecified activity	0.001	0.998	0.000
G82.0 Flaccid paraplegia	0.000	0.998	0.002
L05 Pilonidal cyst	0.000	0.998	0.002
L40-L45 Papulosquamous disorders	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.001
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.001	0.998	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
H16.0 Corneal ulcer	0.002	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.998	0.002
H73.0 Acute myringitis	0.000	0.998	0.002
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
S02.5 Fracture of tooth	0.000	0.998	0.002
S02.4 Fracture of malar and maxillary bones	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.002	0.998	0.000
M07.68 Other enteropathic arthropathies (Other)	0.001	0.998	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.001	0.998	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.001	0.998	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.001	0.998	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.001	0.998	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.001	0.998	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.001	0.998	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.001	0.998	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.001	0.998	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.000	0.998	0.002
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.001	0.998	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.001	0.998	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.001	0.998	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.001	0.998	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.001	0.998	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.001	0.998	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.001	0.998	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.001	0.998	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.001	0.998	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.001	0.998	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.001	0.998	0.000
M07.18 Arthritis mutilans (Other)	0.001	0.998	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.001	0.998	0.000
M07.16 Arthritis mutilans (Lower leg)	0.001	0.998	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.001	0.998	0.000
M07.14 Arthritis mutilans (Hand)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations