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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12582852
log Bayes Factor = 14.3759
Chromosome 12   position 3,315,933  (GRCh37) Explore rs12582852 on Ensembl!
Variant rs12582852 is part of Cluster X0106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
J34 Other disorders of nose and nasal sinuses
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.996 0.004 0.000
Z51 Other medical care
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.992 0.008 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.992 0.008 0.000
R50.9 Fever, unspecified
0.991 0.009 0.000
R50 Fever of unknown origin
0.990 0.010 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.989 0.011 0.000
M50-M54 Other dorsopathies
0.987 0.013 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.986 0.014 0.000
Z96 Presence of other functional implants
0.985 0.015 0.000
Z47 Other orthopaedic follow-up care
0.981 0.019 0.000
Z51.0 Radiotherapy session
0.978 0.022 0.000
Chapter XIV Diseases of the genitourinary system
0.975 0.025 0.000
M54 Dorsalgia
0.974 0.026 0.000
N10-N16 Renal tubulo-interstitial diseases
0.974 0.026 0.000
Z85 Personal history of malignant neoplasm
0.973 0.027 0.000
C15-C26 Malignant neoplasms of digestive organs
0.967 0.033 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.964 0.036 0.000
J00-J06 Acute upper respiratory infections
0.961 0.039 0.000
M54.5 Low back pain
0.960 0.040 0.000
C77.0 Lymph nodes of head, face and neck
0.960 0.040 0.000
N13 Obstructive and reflux uropathy
0.958 0.042 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.958 0.042 0.000
C18 Malignant neoplasm of colon
0.955 0.045 0.000
R63 Symptoms and signs concerning food and fluid intake
0.950 0.050 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.947 0.053 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.947 0.053 0.000
N25-N29 Other disorders of kidney and ureter
0.947 0.053 0.000
J34.2 Deviated nasal septum
0.945 0.055 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.943 0.057 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.941 0.059 0.000
M20-M25 Other joint disorders
0.935 0.065 0.000
R59 Enlarged lymph nodes
0.934 0.066 0.000
Z80 Family history of malignant neoplasm
0.933 0.067 0.000
M65-M68 Disorders of synovium and tendon
0.931 0.069 0.000
R53 Malaise and fatigue
0.931 0.069 0.000
S80-S89 Injuries to the knee and lower leg
0.931 0.069 0.000
J34.3 Hypertrophy of nasal turbinates
0.930 0.070 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.926 0.074 0.000
R63.0 Anorexia
0.925 0.075 0.000
C18.9 Colon, unspecified
0.922 0.078 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.920 0.080 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.917 0.083 0.000
C77.3 Axillary and upper limb lymph nodes
0.914 0.086 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.914 0.086 0.000
Z96.8 Presence of other specified functional implants
0.912 0.088 0.000
M25 Other joint disorders, not elsewhere classified
0.908 0.092 0.000
M54.56 Low back pain (Lumbar region)
0.906 0.094 0.000
N13.3 Other and unspecified hydronephrosis
0.906 0.094 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.902 0.098 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.901 0.099 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.899 0.101 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.896 0.104 0.000
Chapter XX External causes of morbidity and mortality
0.895 0.105 0.000
M54.59 Low back pain (Site unspecified)
0.895 0.105 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.891 0.109 0.000
J03 Acute tonsillitis
0.887 0.113 0.000
M50 Cervical disk disorders
0.885 0.115 0.000
C18.2 Ascending colon
0.884 0.116 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.882 0.118 0.000
Chapter I Certain infectious and parasitic diseases
0.882 0.118 0.000
S40-S49 Injuries to the shoulder and upper arm
0.880 0.120 0.000
Z96.6 Presence of orthopaedic joint implants
0.876 0.124 0.000
R59.0 Localised enlarged lymph nodes
0.874 0.126 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.873 0.127 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.872 0.128 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.870 0.130 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.867 0.133 0.000
S20-S29 Injuries to the thorax
0.864 0.136 0.000
Z40 Prophylactic surgery
0.864 0.136 0.000
Z96.1 Presence of intraocular lens
0.863 0.137 0.000
Z92 Personal history of medical treatment
0.862 0.138 0.000
J38.7 Other diseases of larynx
0.859 0.141 0.000
M65 Synovitis and tenosynovitis
0.858 0.142 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.858 0.142 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.855 0.145 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.854 0.146 0.000
Z45 Adjustment and management of implanted device
0.853 0.147 0.000
N28.8 Other specified disorders of kidney and ureter
0.852 0.148 0.000
T81 Complications of procedures, not elsewhere classified
0.852 0.148 0.000
Z96.7 Presence of other bone and tendon implants
0.849 0.151 0.000
C34 Malignant neoplasm of bronchus and lung
0.848 0.152 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.848 0.152 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.846 0.154 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.844 0.156 0.000
C64-C68 Malignant neoplasms of urinary tract
0.844 0.156 0.000
Z92.3 Personal history of irradiation
0.843 0.157 0.000
D69 Purpura and other haemorrhagic conditions
0.843 0.157 0.000
Z46 Fitting and adjustment of other devices
0.843 0.157 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.841 0.159 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.841 0.159 0.000
C77.2 Intra-abdominal lymph nodes
0.839 0.161 0.000
R51 Headache
0.839 0.161 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.837 0.162 0.000
J02 Acute pharyngitis
0.837 0.163 0.000
T79-T79 Certain early complications of trauma
0.836 0.164 0.000
J03.9 Acute tonsillitis, unspecified
0.834 0.166 0.000
C50-C50 Malignant neoplasm of breast
0.834 0.166 0.000
M25.4 Effusion of joint
0.834 0.166 0.000
M86-M90 Other osteopathies
0.833 0.167 0.000
Z94 Transplanted organ and tissue status
0.833 0.167 0.000
Z51.2 Other chemotherapy
0.830 0.170 0.000
J95-J99 Other diseases of the respiratory system
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.823 0.177 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.823 0.177 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.822 0.178 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.822 0.178 0.000
Z47.8 Other specified orthopaedic follow-up care
0.821 0.179 0.000
R68 Other general symptoms and signs
0.817 0.183 0.000
Z48 Other surgical follow-up care
0.817 0.183 0.000
Z41 Procedures for purposes other than remedying health state
0.816 0.184 0.000
M54.4 Lumbago with sciatica
0.811 0.188 0.000
T86 Failure and rejection of transplanted organs and tissues
0.811 0.189 0.000
Z98 Other postsurgical states
0.810 0.190 0.000
S60-S69 Injuries to the wrist and hand
0.807 0.193 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.805 0.195 0.000
M25.5 Pain in joint
0.799 0.201 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.798 0.202 0.000
C17 Malignant neoplasm of small intestine
0.798 0.202 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.798 0.202 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.797 0.203 0.000
M50.0 Cervical disk disorder with myelopathy
0.797 0.203 0.000
C92 Myeloid leukaemia
0.795 0.205 0.000
C79 Secondary malignant neoplasm of other sites
0.795 0.205 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.792 0.208 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.792 0.208 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.792 0.208 0.000
Z49 Care involving dialysis
0.791 0.209 0.000
M91-M94 Chondropathies
0.791 0.209 0.000
C18.7 Sigmoid colon
0.789 0.211 0.000
Z97 Presence of other devices
0.789 0.211 0.000
J38.1 Polyp of vocal cord and larynx
0.788 0.212 0.000
Z51.1 Chemotherapy session for neoplasm
0.787 0.213 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.786 0.213 0.000
M40-M43 Deforming dorsopathies
0.786 0.214 0.000
Z99.2 Dependence on renal dialysis
0.785 0.215 0.000
C77.1 Intrathoracic lymph nodes
0.782 0.218 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.781 0.219 0.000
M25.46 Effusion of joint (Lower leg)
0.781 0.219 0.000
N13.4 Hydroureter
0.780 0.220 0.000
M54.57 Low back pain (Lumbosacral region)
0.778 0.222 0.000
M24 Other specific joint derangements
0.776 0.224 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.776 0.224 0.000
Z51.5 Palliative care
0.775 0.225 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.774 0.226 0.000
S83.2 Tear of meniscus, current
0.774 0.226 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.774 0.226 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.774 0.226 0.000
M80-M85 Disorders of bone density and structure
0.772 0.228 0.000
M65.3 Trigger finger
0.771 0.229 0.000
J81 Pulmonary oedema
0.771 0.229 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.770 0.230 0.000
M60-M63 Disorders of muscles
0.768 0.232 0.000
N26 Unspecified contracted kidney
0.767 0.233 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.767 0.233 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.766 0.234 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.766 0.234 0.000
C85.1 B-cell lymphoma, unspecified
0.766 0.234 0.000
N99-N99 Other disorders of the genitourinary system
0.765 0.235 0.000
N27 Small kidney of unknown cause
0.765 0.235 0.000
M54.1 Radiculopathy
0.761 0.239 0.000
C77.4 Inguinal and lower limb lymph nodes
0.760 0.240 0.000
J38.4 Oedema of larynx
0.758 0.242 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.757 0.243 0.000
R52 Pain, not elsewhere classified
0.755 0.245 0.000
R58 Haemorrhage, not elsewhere classified
0.755 0.245 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.755 0.245 0.000
S81 Open wound of lower leg
0.754 0.246 0.000
Z81 Family history of mental and behavioural disorders
0.752 0.247 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.752 0.248 0.000
M21 Other acquired deformities of limbs
0.751 0.249 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.749 0.251 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.749 0.251 0.000
J02.9 Acute pharyngitis, unspecified
0.748 0.252 0.000
S80 Superficial injury of lower leg
0.747 0.253 0.000
M34 Systemic sclerosis
0.745 0.255 0.000
Z80.3 Family history of malignant neoplasm of breast
0.745 0.255 0.000
C78.2 Secondary malignant neoplasm of pleura
0.744 0.256 0.000
M22 Disorders of patella
0.743 0.257 0.000
T93 Sequelae of injuries of lower limb
0.743 0.257 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.743 0.257 0.000
J39 Other diseases of upper respiratory tract
0.742 0.258 0.000
Z80.6 Family history of leukaemia
0.742 0.258 0.000
A30-A49 Other bacterial diseases
0.742 0.258 0.000
J35 Chronic diseases of tonsils and adenoids
0.742 0.258 0.000
D69.6 Thrombocytopenia, unspecified
0.742 0.258 0.000
C34.3 Lower lobe, bronchus or lung
0.742 0.258 0.000
M66 Spontaneous rupture of synovium and tendon
0.740 0.260 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.740 0.260 0.000
J00 Acute nasopharyngitis [common cold]
0.739 0.261 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.738 0.262 0.000
D66 Hereditary factor VIII deficiency
0.736 0.264 0.000
R59.9 Enlarged lymph nodes, unspecified
0.735 0.265 0.000
R47-R49 Symptoms and signs involving speech and voice
0.735 0.265 0.000
Z91.5 Personal history of self-harm
0.734 0.266 0.000
D45 Polycythaemia vera
0.732 0.268 0.000
M00-M03 Infectious arthropathies
0.731 0.269 0.000
M54.2 Cervicalgia
0.730 0.270 0.000
Z46.6 Fitting and adjustment of urinary device
0.730 0.270 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.730 0.270 0.000
N13.6 Pyonephrosis
0.729 0.271 0.000
J04 Acute laryngitis and tracheitis
0.729 0.271 0.000
S70-S79 Injuries to the hip and thigh
0.727 0.272 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.726 0.274 0.000
C77.9 Lymph node, unspecified
0.726 0.274 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.725 0.275 0.000
R63.4 Abnormal weight loss
0.724 0.276 0.000
Z52 Donors of organs and tissues
0.724 0.276 0.000
M50.1 Cervical disk disorder with radiculopathy
0.723 0.277 0.000
N28.1 Cyst of kidney, acquired
0.722 0.278 0.000
R40 Somnolence, stupor and coma
0.720 0.280 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.719 0.281 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.718 0.282 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.718 0.282 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.718 0.282 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
M53 Other dorsopathies, not elsewhere classified
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
J37 Chronic laryngitis and laryngotracheitis
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.715 0.284 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.715 0.285 0.000
C50 Malignant neoplasm of breast
0.715 0.285 0.000
C80 Malignant neoplasm without specification of site
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
C32 Malignant neoplasm of larynx
0.715 0.285 0.000
Z84 Family history of other conditions
0.714 0.286 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.714 0.286 0.000
Z51.9 Medical care, unspecified
0.713 0.287 0.000
Z51.6 Desensitisation to allergens
0.713 0.287 0.000
N13.8 Other obstructive and reflux uropathy
0.713 0.287 0.000
Z42 Follow-up care involving plastic surgery
0.713 0.287 0.000
Z48.9 Surgical follow-up care, unspecified
0.712 0.288 0.000
Q50-Q56 Congenital malformations of genital organs
0.711 0.289 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.711 0.289 0.000
R62 Lack of expected normal physiological development
0.711 0.289 0.000
R64 Cachexia
0.711 0.289 0.000
C77.8 Lymph nodes of multiple regions
0.711 0.289 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.711 0.289 0.000
R50.2 Drug-induced fever
0.710 0.290 0.000
R50.1 Persistent fever
0.710 0.290 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.710 0.290 0.000
R57 Shock, not elsewhere classified
0.709 0.291 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.709 0.291 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.709 0.291 0.000
M65.34 Trigger finger-Hand
0.709 0.291 0.000
D48.1 Connective and other soft tissue
0.708 0.292 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.707 0.293 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.707 0.293 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
C95 Leukaemia of unspecified cell type
0.707 0.293 0.000
C94 Other leukaemias of specified cell type
0.707 0.293 0.000
C93 Monocytic leukaemia
0.707 0.293 0.000
C88 Malignant immunoproliferative diseases
0.707 0.293 0.000
C86 Other specified types of T/NK-cell lymphoma
0.707 0.293 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.707 0.293 0.000
Q80-Q89 Other congenital malformations
0.707 0.293 0.000
Z96.9 Presence of functional implant, unspecified
0.706 0.293 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.706 0.293 0.000
Z96.4 Presence of endocrine implants
0.706 0.293 0.000
Z96.3 Presence of artificial larynx
0.706 0.293 0.000
Z96.2 Presence of otological and audiological implants
0.706 0.293 0.000
M25.3 Other instability of joint
0.705 0.295 0.000
D60-D64 Aplastic and other anaemias
0.705 0.295 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.705 0.295 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.703 0.296 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.703 0.297 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.703 0.297 0.000
R45 Symptoms and signs involving emotional state
0.703 0.297 0.000
J38.3 Other diseases of vocal cords
0.703 0.297 0.000
Z45.2 Adjustment and management of vascular access device
0.702 0.298 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.298 0.000
C18.0 Caecum
0.700 0.300 0.000
S43.0 Dislocation of shoulder joint
0.700 0.300 0.000
J09-J18 Influenza and pneumonia
0.699 0.301 0.000
M54.8 Other dorsalgia
0.698 0.302 0.000
M54.6 Pain in thoracic spine
0.698 0.302 0.000
M54.0 Panniculitis affecting regions of neck and back
0.698 0.302 0.000
C25 Malignant neoplasm of pancreas
0.698 0.302 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.698 0.302 0.000
N15 Other renal tubulo-interstitial diseases
0.698 0.302 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.698 0.302 0.000
N11 Chronic tubulo-interstitial nephritis
0.698 0.302 0.000
B35-B49 Mycoses
0.698 0.302 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.697 0.302 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.697 0.302 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.697 0.303 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.697 0.303 0.000
Z83 Family history of other specific disorders
0.697 0.303 0.000
D48.5 Skin
0.696 0.304 0.000
C50.9 Breast, unspecified
0.696 0.304 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.696 0.304 0.000
M87 Osteonecrosis
0.696 0.304 0.000
R59.1 Generalised enlarged lymph nodes
0.694 0.306 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.694 0.306 0.000
M25.8 Other specified joint disorders
0.694 0.306 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.693 0.307 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.693 0.307 0.000
C21 Malignant neoplasm of anus and anal canal
0.693 0.307 0.000
C23 Malignant neoplasm of gallbladder
0.693 0.307 0.000
T17 Foreign body in respiratory tract
0.693 0.307 0.000
Z93 Artificial opening status
0.693 0.307 0.000
R68.8 Other specified general symptoms and signs
0.692 0.308 0.000
M67 Other disorders of synovium and tendon
0.692 0.308 0.000
N17-N19 Renal failure
0.692 0.308 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.692 0.308 0.000
C34.9 Bronchus or lung, unspecified
0.691 0.309 0.000
Z92.8 Personal history of other medical treatment
0.689 0.311 0.000
T92 Sequelae of injuries of upper limb
0.689 0.311 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.689 0.311 0.000
J01 Acute sinusitis
0.689 0.311 0.000
M54.55 Low back pain (Thoracolumbar region)
0.689 0.311 0.000
M54.54 Low back pain-Thoracic
0.689 0.311 0.000
M54.53 Low back pain-Cervicothoracic
0.689 0.311 0.000
M54.52 Low back pain-Cervical
0.689 0.311 0.000
M54.51 Low back pain-Occipit-atl-axl
0.689 0.311 0.000
M54.50 Low back pain (Multiple sites in spine)
0.689 0.311 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.687 0.313 0.000
C20 Malignant neoplasm of rectum
0.687 0.313 0.000
D75 Other diseases of blood and blood-forming organs
0.687 0.313 0.000
S89 Other and unspecified injuries of lower leg
0.685 0.315 0.000
M45-M49 Spondylopathies
0.685 0.315 0.000
C18.8 Overlapping lesion of colon
0.685 0.315 0.000
C18.5 Splenic flexure
0.685 0.315 0.000
C18.1 Appendix
0.685 0.315 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.685 0.315 0.000
D46 Myelodysplastic syndromes
0.683 0.317 0.000
M25.53 Pain in joint (Forearm)
0.683 0.317 0.000
C01 Malignant neoplasm of base of tongue
0.682 0.318 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.681 0.319 0.000
R63.5 Abnormal weight gain
0.681 0.319 0.000
R63.3 Feeding difficulties and mismanagement
0.681 0.319 0.000
R63.2 Polyphagia
0.681 0.319 0.000
R63.1 Polydipsia
0.681 0.319 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.681 0.319 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.680 0.320 0.000
R56 Convulsions, not elsewhere classified
0.679 0.320 0.000
J38.6 Stenosis of larynx
0.679 0.321 0.000
J38.5 Laryngeal spasm
0.679 0.321 0.000
J38.2 Nodules of vocal cords
0.679 0.321 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.679 0.321 0.000
N25 Disorders resulting from impaired renal tubular function
0.679 0.321 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.677 0.323 0.000
Z98.8 Other specified postsurgical states
0.677 0.323 0.000
C17.9 Small intestine, unspecified
0.677 0.323 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.676 0.324 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.676 0.324 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.676 0.324 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.676 0.324 0.000
C92.0 Acute myeloid leukaemia
0.676 0.324 0.000
D55-D59 Haemolytic anaemias
0.674 0.325 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.674 0.326 0.000
Z97.8 Presence of other specified devices
0.674 0.326 0.000
M25.7 Osteophyte
0.674 0.326 0.000
C81 Hodgkin's disease
0.674 0.326 0.000
Z51.3 Blood transfusion without reported diagnosis
0.673 0.326 0.000
R50.8 Other specified fever
0.673 0.326 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.672 0.327 0.000
J30 Vasomotor and allergic rhinitis
0.672 0.328 0.000
C66 Malignant neoplasm of ureter
0.672 0.328 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.671 0.329 0.000
M33 Dermatopolymyositis
0.671 0.329 0.000
M32 Systemic lupus erythematosus
0.671 0.329 0.000
M30 Polyarteritis nodosa and related conditions
0.671 0.329 0.000
S40 Superficial injury of shoulder and upper arm
0.670 0.330 0.000
C79.2 Secondary malignant neoplasm of skin
0.670 0.330 0.000
A49 Bacterial infection of unspecified site
0.670 0.330 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.669 0.331 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.669 0.331 0.000
S27 Injury of other and unspecified intrathoracic organs
0.669 0.331 0.000
B99-B99 Other infectious diseases
0.669 0.331 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.668 0.332 0.000
C34.1 Upper lobe, bronchus or lung
0.668 0.332 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.668 0.332 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.667 0.332 0.000
Z94.7 Corneal transplant status
0.667 0.333 0.000
D80-D89 Certain disorders involving the immune mechanism
0.667 0.333 0.000
S88 Traumatic amputation of lower leg
0.667 0.333 0.000
S87 Crushing injury of lower leg
0.667 0.333 0.000
S86 Injury of muscle and tendon at lower leg level
0.667 0.333 0.000
S85 Injury of blood vessels at lower leg level
0.667 0.333 0.000
S84 Injury of nerves at lower leg level
0.667 0.333 0.000
M50.3 Other cervical disk degeneration
0.667 0.333 0.000
V10-V19 Pedal cyclist injured in transport accident
0.666 0.334 0.000
J33 Nasal polyp
0.666 0.334 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.666 0.334 0.000
B95-B98 Bacterial, viral and other infectious agents
0.666 0.334 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.665 0.335 0.000
Z94.8 Other transplanted organ and tissue status
0.665 0.335 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.665 0.335 0.000
X20-X29 Contact with venomous animals and plants
0.664 0.335 0.000
T87 Complications peculiar to reattachment and amputation
0.664 0.336 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.664 0.336 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.662 0.338 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.662 0.338 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.662 0.338 0.000
Y40 Systemic antibiotics
0.661 0.339 0.000
J38.0 Paralysis of vocal cords and larynx
0.660 0.340 0.000
C09 Malignant neoplasm of tonsil
0.660 0.340 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.660 0.340 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.660 0.340 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.660 0.340 0.000
C31 Malignant neoplasm of accessory sinuses
0.660 0.340 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.660 0.340 0.000
C37 Malignant neoplasm of thymus
0.660 0.340 0.000
C33 Malignant neoplasm of trachea
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.659 0.341 0.000
J60-J70 Lung diseases due to external agents
0.659 0.341 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.657 0.343 0.000
C82.6 Cutaneous follicle centre lymphoma
0.657 0.343 0.000
C82.5 Diffuse follicle centre lymphoma
0.657 0.343 0.000
C82.4 Follicular lymphoma grade IIIb
0.657 0.343 0.000
C82.3 Follicular lymphoma grade IIIa
0.657 0.343 0.000
C82.2 Large cell, follicular
0.657 0.343 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.657 0.343 0.000
C82.0 Small cleaved cell, follicular
0.657 0.343 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.655 0.345 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.655 0.345 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.655 0.345 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.655 0.345 0.000
C85.0 Lymphosarcoma
0.655 0.345 0.000
Q60-Q64 Congenital malformations of the urinary system
0.655 0.345 0.000
Chapter VI Diseases of the nervous system
0.654 0.346 0.000
S62 Fracture at wrist and hand level
0.654 0.346 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.654 0.346 0.000
M43 Other deforming dorsopathies
0.653 0.347 0.000
J98 Other respiratory disorders
0.653 0.347 0.000
J84 Other interstitial pulmonary diseases
0.653 0.347 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.652 0.348 0.000
C18.3 Hepatic flexure
0.652 0.348 0.000
T86.1 Kidney transplant failure and rejection
0.652 0.348 0.000
M25.9 Joint disorder, unspecified
0.651 0.349 0.000
M25.2 Flail joint
0.651 0.349 0.000
M25.1 Fistula of joint
0.651 0.349 0.000
M25.0 Haemarthrosis
0.651 0.349 0.000
D68 Other coagulation defects
0.649 0.351 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.649 0.351 0.000
R80 Isolated proteinuria
0.648 0.352 0.000
M54.3 Sciatica
0.648 0.352 0.000
T79.6 Traumatic ischaemia of muscle
0.647 0.353 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.647 0.353 0.000
X60-X84 Intentional self-harm
0.647 0.353 0.000
M25.54 Pain in joint (Hand)
0.647 0.353 0.000
N28.0 Ischaemia and infarction of kidney
0.646 0.353 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.646 0.354 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.646 0.354 0.000
Q35-Q37 Cleft lip and cleft palate
0.646 0.354 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.646 0.354 0.000
Q00-Q07 Congenital malformations of the nervous system
0.646 0.354 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.645 0.355 0.000
D48.0 Bone and articular cartilage
0.645 0.355 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.644 0.356 0.000
S80.8 Other superficial injuries of lower leg
0.644 0.356 0.000
M89 Other disorders of bone
0.643 0.357 0.000
M94 Other disorders of cartilage
0.642 0.357 0.000
D67 Hereditary factor IX deficiency
0.642 0.358 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.642 0.358 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.642 0.358 0.000
M22.2 Patellofemoral disorders
0.642 0.358 0.000
Z85.6 Personal history of leukaemia
0.642 0.358 0.000
N10 Acute tubulo-interstitial nephritis
0.642 0.358 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.642 0.358 0.000
Y35-Y36 Legal intervention and operations of war
0.642 0.358 0.000
Y10-Y34 Event of undetermined intent
0.642 0.358 0.000
Y00-Y09 Assault
0.642 0.358 0.000
X85-X99 Assault
0.642 0.358 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.642 0.358 0.000
X50-X57 Overexertion, travel and privation
0.642 0.358 0.000
X30-X39 Exposure to forces of nature
0.642 0.358 0.000
X10-X19 Contact with heat and hot substances
0.642 0.358 0.000
X00-X09 Exposure to smoke, fire and flames
0.642 0.358 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.642 0.358 0.000
W75-W84 Other accidental threats to breathing
0.642 0.358 0.000
W65-W74 Accidental drowning and submersion
0.642 0.358 0.000
W50-W64 Exposure to animate mechanical forces
0.642 0.358 0.000
V98-V99 Other and unspecified transport accidents
0.642 0.358 0.000
V95-V97 Air and space transport accidents
0.642 0.358 0.000
V90-V94 Water transport accidents
0.642 0.358 0.000
V70-V79 Bus occupant injured in transport accident
0.642 0.358 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.642 0.358 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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