TreeWAS – Variant ID: rs12602901

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C15.5 Lower third of oesophagus	0.204	0.796	0.000
C15.9 Oesophagus, unspecified	0.203	0.797	0.000
C15 Malignant neoplasm of oesophagus	0.201	0.799	0.000
C15.3 Upper third of oesophagus	0.172	0.828	0.000
C15.0 Cervical part of oesophagus	0.156	0.844	0.000
C15.8 Overlapping lesion of oesophagus	0.144	0.856	0.000
C15.2 Abdominal part of oesophagus	0.144	0.856	0.000
C15.1 Thoracic part of oesophagus	0.144	0.856	0.000
C15.4 Middle third of oesophagus	0.135	0.865	0.000
E66.8 Other obesity	0.133	0.867	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.898	0.102
S02.4 Fracture of malar and maxillary bones	0.000	0.908	0.092
S02.20 Fracture of nasal bones (closed)	0.000	0.914	0.086
S02 Fracture of skull and facial bones	0.000	0.914	0.086
S02.2 Fracture of nasal bones	0.000	0.915	0.085
S02.8 Fractures of other skull and facial bones	0.000	0.923	0.077
S02.1 Fracture of base of skull	0.000	0.927	0.073
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.930	0.070
S02.3 Fracture of orbital floor	0.000	0.933	0.067
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.934	0.066
S02.10 Fracture of base of skull (closed)	0.000	0.936	0.064
S02.7 Multiple fractures involving skull and facial bones	0.000	0.938	0.062
S02.21 Fracture of nasal bones (open)	0.000	0.939	0.061
S02.6 Fracture of mandible	0.000	0.941	0.059
S02.81 Fractures of other skull and facial bones (open)	0.000	0.945	0.055
S02.30 Fracture of orbital floor (closed)	0.000	0.946	0.054
S02.11 Fracture of base of skull (open)	0.000	0.947	0.053
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.950	0.050
S02.5 Fracture of tooth	0.000	0.950	0.050
S02.31 Fracture of orbital floor (open)	0.000	0.952	0.048
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.955	0.044
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.955	0.044
S02.0 Fracture of vault of skull	0.000	0.957	0.043
E66 Obesity	0.043	0.957	0.000
S02.61 Fracture of mandible (open)	0.000	0.958	0.042
S02.60 Fracture of mandible (closed)	0.000	0.960	0.040
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.964	0.036
S02.51 Fracture of tooth (open)	0.000	0.964	0.036
E66.2 Extreme obesity with alveolar hypoventilation	0.036	0.964	0.000
E66.0 Obesity due to excess calories	0.032	0.968	0.000
E66.1 Drug-induced obesity	0.031	0.969	0.000
S02.01 Fracture of vault of skull (open)	0.001	0.975	0.025
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.001	0.975	0.024
S02.50 Fracture of tooth (closed)	0.000	0.975	0.025
S02.00 Fracture of vault of skull (closed)	0.000	0.977	0.023
M25.74 Osteophyte (Hand)	0.000	0.982	0.018
C16.0 Cardia	0.017	0.983	0.000
C15-C26 Malignant neoplasms of digestive organs	0.016	0.984	0.000
C16 Malignant neoplasm of stomach	0.016	0.984	0.000
C16.1 Fundus of stomach	0.013	0.986	0.000
C23 Malignant neoplasm of gallbladder	0.014	0.986	0.000
C21 Malignant neoplasm of anus and anal canal	0.013	0.987	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.012	0.988	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.012	0.988	0.000
C16.8 Overlapping lesion of stomach	0.012	0.988	0.000
C16.4 Pylorus	0.012	0.988	0.000
E65-E68 Obesity and other hyperalimentation	0.011	0.988	0.000
C16.6 Greater curvature of stomach, unspecified	0.011	0.989	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.011	0.989	0.000
C16.2 Body of stomach	0.010	0.989	0.000
C16.3 Pyloric antrum	0.010	0.989	0.000
C16.5 Lesser curvature of stomach, unspecified	0.010	0.990	0.000
C24.0 Extrahepatic bile duct	0.010	0.990	0.000
C21.1 Anal canal	0.010	0.990	0.000
C21.2 Cloacogenic zone	0.009	0.990	0.000
C16.9 Stomach, unspecified	0.009	0.991	0.000
C26.9 Ill-defined sites within the digestive system	0.009	0.991	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.009	0.991	0.000
C17 Malignant neoplasm of small intestine	0.009	0.991	0.000
C24.8 Overlapping lesion of biliary tract	0.009	0.991	0.000
C26.8 Overlapping lesion of digestive system	0.009	0.991	0.000
C26.1 Spleen	0.009	0.991	0.000
C24.9 Biliary tract, unspecified	0.009	0.991	0.000
C26.0 Intestinal tract, part unspecified	0.008	0.991	0.000
E67 Other hyperalimentation	0.008	0.991	0.000
E68 Sequelae of hyperalimentation	0.008	0.991	0.000
C21.0 Anus, unspecified	0.008	0.992	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.008	0.992	0.000
M25.7 Osteophyte	0.000	0.992	0.008
C17.1 Jejunum	0.007	0.993	0.000
M25.78 Osteophyte (Other)	0.000	0.993	0.007
C22.7 Other specified carcinomas of liver	0.007	0.993	0.000
C22.4 Other sarcomas of liver	0.007	0.993	0.000
C22.3 Angiosarcoma of liver	0.007	0.993	0.000
C22.2 Hepatoblastoma	0.007	0.993	0.000
C24.1 Ampulla of Vater	0.006	0.993	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.993	0.007
C17.8 Overlapping lesion of small intestine	0.006	0.993	0.000
C17.3 Meckel's diverticulum	0.006	0.993	0.000
C22.1 Intrahepatic bile duct carcinoma	0.006	0.993	0.000
E67.8 Other specified hyperalimentation	0.006	0.994	0.000
E67.3 Hypervitaminosis D	0.006	0.994	0.000
E67.2 Megavitamin-B6 syndrome	0.006	0.994	0.000
E67.1 Hypercarotenaemia	0.006	0.994	0.000
E67.0 Hypervitaminosis A	0.006	0.994	0.000
C22.0 Liver cell carcinoma	0.006	0.994	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.994	0.006
C17.0 Duodenum	0.006	0.994	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.994	0.006
M25.73 Osteophyte (Forearm)	0.000	0.994	0.006
M25.70 Osteophyte (Multiple sites)	0.000	0.994	0.006
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
C20 Malignant neoplasm of rectum	0.006	0.994	0.000
C17.9 Small intestine, unspecified	0.005	0.994	0.000
E65 Localised adiposity	0.005	0.995	0.000
C22.9 Liver, unspecified	0.005	0.995	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.995	0.005
I44.0 Atrioventricular block, first degree	0.005	0.995	0.000
C17.2 Ileum	0.005	0.995	0.000
D86 Sarcoidosis	0.005	0.995	0.000
C25 Malignant neoplasm of pancreas	0.004	0.995	0.001
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.996	0.004
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
R01.1 Cardiac murmur, unspecified	0.004	0.996	0.000
I44.1 Atrioventricular block, second degree	0.004	0.996	0.000
R01.0 Benign and innocent cardiac murmurs	0.004	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.004	0.996	0.000
Q21.1 Atrial septal defect	0.004	0.996	0.000
M25.71 Osteophyte (Shoulder region)	0.000	0.996	0.004
L50.9 Urticaria, unspecified	0.004	0.996	0.000
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
S43.0 Dislocation of shoulder joint	0.004	0.996	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.996	0.004
C25.4 Endocrine pancreas	0.003	0.996	0.001
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
D86.1 Sarcoidosis of lymph nodes	0.004	0.996	0.000
I44 Atrioventricular and left bundle-branch block	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.996	0.001
C25.7 Other parts of pancreas	0.003	0.996	0.001
K22.9 Disease of oesophagus, unspecified	0.004	0.996	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.004	0.996	0.000
R01 Cardiac murmurs and other cardiac sounds	0.003	0.997	0.000
C25.3 Pancreatic duct	0.003	0.997	0.001
C25.2 Tail of pancreas	0.003	0.997	0.001
I44.2 Atrioventricular block, complete	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
K05.3 Chronic periodontitis	0.000	0.997	0.003
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
I44.6 Other and unspecified fascicular block	0.003	0.997	0.000
C25.9 Pancreas, unspecified	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
C25.1 Body of pancreas	0.002	0.997	0.001
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
I44.5 Left posterior fascicular block	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
I44.4 Left anterior fascicular block	0.003	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.997	0.000
R01.2 Other cardiac sounds	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
D07.5 Prostate	0.000	0.997	0.003
C25.0 Head of pancreas	0.002	0.997	0.001
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.997	0.003
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.997	0.000
Y52.7 Peripheral vasodilators	0.002	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
L57.0 Actinic keratosis	0.000	0.998	0.002
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
D84.1 Defects in the complement system	0.002	0.998	0.000
C44.7 Skin of lower limb, including hip	0.000	0.998	0.002
R27.0 Ataxia, unspecified	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.000	0.998	0.002
S06.9 Intracranial injury, unspecified	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.002
S06 Intracranial injury	0.000	0.998	0.002
W25.9 Unspecified place	0.002	0.998	0.000
R00.2 Palpitations	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.998	0.002
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
S00-S09 Injuries to the head	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
I44.3 Other and unspecified atrioventricular block	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
L50 Urticaria	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.998	0.002
D07.1 Vulva	0.000	0.998	0.002
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.998	0.002
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
R10.2 Pelvic and perineal pain	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.002	0.998	0.000
W25.8 Other specified place	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
E88 Other metabolic disorders	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.998	0.002
S00.9 Superficial injury of head, part unspecified	0.002	0.998	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.998	0.002
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.002
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
Y54.5 Other diuretics	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
L50.1 Idiopathic urticaria	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
S08 Traumatic amputation of part of head	0.000	0.998	0.002
S07 Crushing injury of head	0.000	0.998	0.002
S04 Injury of cranial nerves	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.998	0.002
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.998	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.998	0.002
D09.0 Bladder	0.002	0.998	0.000
E88.2 Lipomatosis, not elsewhere classified	0.000	0.998	0.002
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
L50.6 Contact urticaria	0.001	0.998	0.000
L50.5 Cholinergic urticaria	0.001	0.998	0.000
L50.4 Vibratory urticaria	0.001	0.998	0.000
L50.3 Dermatographic urticaria	0.001	0.998	0.000
L50.2 Urticaria due to cold and heat	0.001	0.998	0.000
B02.3 Zoster ocular disease	0.000	0.998	0.002
K63.8 Other specified diseases of intestine	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.000	0.998	0.002
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.000	0.998	0.001
G61.8 Other inflammatory polyneuropathies	0.000	0.998	0.002
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.002	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
W25 Contact with sharp glass	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.001	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.002	0.998	0.000
E88.9 Metabolic disorder, unspecified	0.000	0.998	0.001
E88.3 Tumour lysis syndrome	0.000	0.998	0.001
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.998	0.001
G53.0 Postzoster neuralgia	0.000	0.998	0.002
I44.7 Left bundle-branch block, unspecified	0.002	0.998	0.000
S29.9 Unspecified injury of thorax	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.998	0.000
Y54.7 Agents affecting calcification	0.001	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.998	0.000
Y54.0 Mineralocorticoids	0.001	0.998	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.001
S06.4 Epidural haemorrhage	0.000	0.998	0.001
S46.2 Injury of muscle and tendon of other parts of biceps	0.001	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.001	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.001
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.001
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.998	0.001
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.998	0.001
Q27.3 Peripheral arteriovenous malformation	0.001	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.001	0.998	0.000
Y44.7 Plasma substitutes	0.001	0.998	0.000
Y44.6 Natural blood and blood products	0.001	0.998	0.000
Y44.5 Thrombolytic drugs	0.001	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.001	0.998	0.000
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.001
C71.1 Frontal lobe	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.998	0.000
D81.4 Nezelof's syndrome	0.001	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.1 Di George's syndrome	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.998	0.000
S06.8 Other intracranial injuries	0.000	0.998	0.001
S46.3 Injury of muscle and tendon of triceps	0.001	0.998	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.998	0.000
Y48.4 Anaesthetic, unspecified	0.001	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
Q25 Congenital malformations of great arteries	0.001	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.998	0.001
J86.0 Pyothorax with fistula	0.000	0.998	0.001
Q25.6 Stenosis of pulmonary artery	0.001	0.998	0.000
Q25.1 Coarctation of aorta	0.001	0.998	0.000
Y48.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
D07.6 Other and unspecified male genital organs	0.000	0.998	0.001
D07.3 Other and unspecified female genital organs	0.000	0.998	0.001
D07.0 Endometrium	0.000	0.998	0.001
H47.1 Papilloedema, unspecified	0.000	0.998	0.001
S04.9 Injury of unspecified cranial nerve	0.000	0.998	0.001
S04.8 Injury of other cranial nerves	0.000	0.998	0.001
S04.7 Injury of accessory nerve	0.000	0.998	0.001
S04.6 Injury of acoustic nerve	0.000	0.998	0.001
S04.5 Injury of facial nerve	0.000	0.998	0.001
S04.4 Injury of abducent nerve	0.000	0.998	0.001
S04.3 Injury of trigeminal nerve	0.000	0.998	0.001
S04.2 Injury of trochlear nerve	0.000	0.998	0.001
S04.1 Injury of oculomotor nerve	0.000	0.998	0.001
S04.0 Injury of optic nerve and pathways	0.000	0.998	0.001
S06.3 Focal brain injury	0.000	0.998	0.001
S06.0 Concussion	0.000	0.998	0.001
S07.9 Crushing injury of head, part unspecified	0.000	0.998	0.001
S07.8 Crushing injury of other parts of head	0.000	0.998	0.001
S07.1 Crushing injury of skull	0.000	0.998	0.001
S07.0 Crushing injury of face	0.000	0.998	0.001
S08.9 Traumatic amputation of unspecified part of head	0.000	0.998	0.001
S08.8 Traumatic amputation of other parts of head	0.000	0.998	0.001
S08.1 Traumatic amputation of ear	0.000	0.998	0.001
S08.0 Avulsion of scalp	0.000	0.998	0.001
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.999	0.001
K22.7 Barrett's oesophagus	0.001	0.999	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.001	0.999	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.001	0.999	0.000
Y48.5 Therapeutic gases	0.001	0.999	0.000
Y48.1 Parenteral anaesthetics	0.001	0.999	0.000
Y48.0 Inhaled anaesthetics	0.001	0.999	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.999	0.000
Y50.8 Other central nervous system stimulants	0.001	0.999	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.999	0.000
Y50.1 Opioid receptor antagonists	0.001	0.999	0.000
Y50.0 Analeptics	0.001	0.999	0.000
Y54.3 Benzothiadiazine derivatives	0.001	0.999	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.999	0.000
Y55.5 Anticommon cold drugs	0.001	0.999	0.000
Y55.4 Expectorants	0.001	0.999	0.000
Y55.3 Antitussives	0.001	0.999	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
Y55.0 Oxytocic drugs	0.001	0.999	0.000
Y58.9 Other and unspecified bacterial vaccines	0.001	0.999	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.001	0.999	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.001	0.999	0.000
Y58.5 Diphtheria vaccine	0.001	0.999	0.000
Y58.4 Tetanus vaccine	0.001	0.999	0.000
Y58.3 Plague vaccine	0.001	0.999	0.000
Y58.2 Cholera vaccine	0.001	0.999	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.001	0.999	0.000
Y58.0 BCG vaccine	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.999	0.001
I08 Multiple valve diseases	0.001	0.999	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.001	0.999	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.999	0.001
E88.8 Other specified metabolic disorders	0.000	0.999	0.001
R82.9 Other and unspecified abnormal finding in urine	0.001	0.999	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.000	0.999	0.001
S03.4 Sprain and strain of jaw	0.000	0.999	0.001
S03.3 Dislocation of other and unspecified parts of head	0.000	0.999	0.001
S03.1 Dislocation of septal cartilage of nose	0.000	0.999	0.001
S03.0 Dislocation of jaw	0.000	0.999	0.001
S49.9 Unspecified injury of shoulder and upper arm	0.001	0.999	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.001	0.999	0.000
D07.4 Penis	0.000	0.999	0.001
I08.0 Disorders of both mitral and aortic valves	0.001	0.999	0.000
L50.8 Other urticaria	0.001	0.999	0.000
W25.6 Industrial and construction area	0.001	0.999	0.000
W25.5 Trade and service area	0.001	0.999	0.000
W25.1 Residential institution	0.001	0.999	0.000
W25.0 Home	0.001	0.999	0.000
W25.7 Farm	0.001	0.999	0.000
W25.4 Street and highway	0.001	0.999	0.000
W25.3 Sports and athletics area	0.001	0.999	0.000
W25.2 School, other institution and public administrative area	0.001	0.999	0.000
E11.1 With ketoacidosis	0.000	0.999	0.001
J86.9 Pyothorax without fistula	0.000	0.999	0.001
Y57.7 Vitamins, not elsewhere classified	0.001	0.999	0.000
Y57.6 Other diagnostic agents	0.001	0.999	0.000
Y57.4 Pharmaceutical excipients	0.001	0.999	0.000
Y57.3 Alcohol deterrents	0.001	0.999	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
Y57.1 Lipotropic drugs	0.001	0.999	0.000
Y57.0 Appetite depressants [anorectics]	0.001	0.999	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.001	0.999	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.999	0.001
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.999	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.001	0.999	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.999	0.001
B35.3 Tinea pedis	0.001	0.999	0.000
D07.2 Vagina	0.000	0.999	0.001
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.999	0.000
S40.0 Contusion of shoulder and upper arm	0.001	0.999	0.000
Y46.6 Other and unspecified antiepileptics	0.001	0.999	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.001	0.999	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.999	0.000
B99 Other and unspecified infectious diseases	0.000	0.999	0.001
S49 Other and unspecified injuries of shoulder and upper arm	0.001	0.999	0.000
Y40 Systemic antibiotics	0.001	0.999	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.999	0.001
I49.9 Cardiac arrhythmia, unspecified	0.001	0.999	0.000
I82.2 Embolism and thrombosis of vena cava	0.001	0.999	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.999	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.999	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.999	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.999	0.000
Q25.3 Stenosis of aorta	0.001	0.999	0.000
Q25.2 Atresia of aorta	0.001	0.999	0.000
Q25.0 Patent ductus arteriosus	0.001	0.999	0.000
S03.2 Dislocation of tooth	0.000	0.999	0.001
Y41.5 Antiviral drugs	0.001	0.999	0.000
Y45.4 Antirheumatics	0.001	0.999	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.999	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.999	0.000
Y47.4 Bromine compounds	0.001	0.999	0.000
Y47.3 Paraldehyde	0.001	0.999	0.000
Y47.2 Chloral derivatives	0.001	0.999	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.999	0.000
Z80.3 Family history of malignant neoplasm of breast	0.000	0.999	0.001
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.999	0.001
S06.01 Concussion (with open intracranial wound)	0.000	0.999	0.001
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.999	0.001
C49.0 Connective and soft tissue of head, face and neck	0.000	0.999	0.001
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations