TreeWAS – Variant ID: rs12628854

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.188	0.812
# Top node	0.187	0.813
Chapter X Diseases of the respiratory system	0.185	0.815
M15-M19 Arthrosis	0.184	0.816
M17 Gonarthrosis [arthrosis of knee]	0.178	0.822
M20-M25 Other joint disorders	0.174	0.826
Chapter VII Diseases of the eye and adnexa	0.174	0.826
J30-J39 Other diseases of upper respiratory tract	0.172	0.828
M19 Other arthrosis	0.169	0.830
Chapter XIV Diseases of the genitourinary system	0.168	0.832
Chapter IX Diseases of the circulatory system	0.168	0.832
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.166	0.834
M17.0 Primary gonarthrosis, bilateral	0.166	0.834
M23 Internal derangement of knee	0.163	0.837
Chapter XII Diseases of the skin and subcutaneous tissue	0.159	0.841
J40-J47 Chronic lower respiratory diseases	0.158	0.842
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.158	0.842
N17-N19 Renal failure	0.157	0.843
H30-H36 Disorders of choroid and retina	0.156	0.844
I60-I69 Cerebrovascular diseases	0.155	0.845
I83 Varicose veins of lower extremities	0.155	0.845
J60-J70 Lung diseases due to external agents	0.154	0.846
Chapter VIII Diseases of the ear and mastoid process	0.154	0.846
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.154	0.846
Chapter V Mental and behavioural disorders	0.153	0.847
Chapter I Certain infectious and parasitic diseases	0.153	0.847
M19.9 Arthrosis, unspecified	0.152	0.848
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.148	0.852
J35 Chronic diseases of tonsils and adenoids	0.148	0.852
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.147	0.853
J90-J94 Other diseases of pleura	0.146	0.854
L80-L99 Other disorders of the skin and subcutaneous tissue	0.146	0.854
M17.1 Other primary gonarthrosis	0.146	0.854
N40-N51 Diseases of male genital organs	0.146	0.854
M65-M68 Disorders of synovium and tendon	0.145	0.855
J80-J84 Other respiratory diseases principally affecting the interstitium	0.143	0.857
I63 Cerebral infarction	0.143	0.857
H35 Other retinal disorders	0.141	0.859
M17.9 Gonarthrosis, unspecified	0.141	0.859
M19.0 Primary arthrosis of other joints	0.141	0.859
M23.2 Derangement of meniscus due to old tear or injury	0.141	0.859
J32 Chronic sinusitis	0.140	0.859
I70-I79 Diseases of arteries, arterioles and capillaries	0.141	0.859
S80-S89 Injuries to the knee and lower leg	0.140	0.860
Chapter IV Endocrine, nutritional and metabolic diseases	0.140	0.860
N19 Unspecified renal failure	0.139	0.861
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.139	0.861
J09-J18 Influenza and pneumonia	0.139	0.861
M40-M43 Deforming dorsopathies	0.137	0.863
M05-M14 Inflammatory polyarthropathies	0.136	0.863
Chapter XX External causes of morbidity and mortality	0.136	0.864
N60-N64 Disorders of breast	0.135	0.865
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.135	0.865
M91-M94 Chondropathies	0.135	0.865
M86-M90 Other osteopathies	0.135	0.865
M60-M63 Disorders of muscles	0.135	0.865
M00-M03 Infectious arthropathies	0.135	0.865
H04 Disorders of lachrymal system	0.135	0.865
Chapter XXII Codes for special purposes	0.134	0.865
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.134	0.865
Chapter XVI Certain conditions originating in the perinatal period	0.134	0.865
M23.4 Loose body in knee	0.134	0.866
I63.9 Cerebral infarction, unspecified	0.134	0.866
M23.8 Other internal derangements of knee	0.134	0.866
J20-J22 Other acute lower respiratory infections	0.134	0.866
S60-S69 Injuries to the wrist and hand	0.134	0.866
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.133	0.867
M70-M79 Other soft tissue disorders	0.133	0.867
J45 Asthma	0.132	0.868
M15 Polyarthrosis	0.132	0.868
M25 Other joint disorders, not elsewhere classified	0.131	0.869
M19.97 Arthrosis, unspecified (Ankle and foot)	0.131	0.869
I67 Other cerebrovascular diseases	0.130	0.869
F40-F48 Neurotic, stress-related and somatoform disorders	0.130	0.870
J35.1 Hypertrophy of tonsils	0.130	0.870
S20-S29 Injuries to the thorax	0.130	0.870
J00-J06 Acute upper respiratory infections	0.129	0.870
H53-H54 Visual disturbances and blindness	0.129	0.871
N17 Acute renal failure	0.129	0.871
E70-E90 Metabolic disorders	0.129	0.871
N20-N23 Urolithiasis	0.128	0.871
J34 Other disorders of nose and nasal sinuses	0.128	0.872
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.128	0.872
J38.0 Paralysis of vocal cords and larynx	0.128	0.872
H43-H45 Disorders of vitreous body and globe	0.128	0.872
M35 Other systemic involvement of connective tissue	0.128	0.872
M17.5 Other secondary gonarthrosis	0.127	0.872
M17.4 Other secondary gonarthrosis, bilateral	0.127	0.872
M17.3 Other posttraumatic gonarthrosis	0.127	0.872
M17.2 Posttraumatic gonarthrosis, bilateral	0.127	0.872
H35.8 Other specified retinal disorders	0.127	0.873
M18 Arthrosis of first carpometacarpal joint	0.127	0.873
N00-N08 Glomerular diseases	0.126	0.873
N18 Chronic renal failure	0.126	0.874
M80-M85 Disorders of bone density and structure	0.125	0.875
M50-M54 Other dorsopathies	0.125	0.875
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.125	0.875
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.125	0.875
M34 Systemic sclerosis	0.125	0.875
M33 Dermatopolymyositis	0.125	0.875
M32 Systemic lupus erythematosus	0.125	0.875
M31 Other necrotising vasculopathies	0.125	0.875
M30 Polyarteritis nodosa and related conditions	0.125	0.875
M24 Other specific joint derangements	0.125	0.875
M22 Disorders of patella	0.125	0.875
M21 Other acquired deformities of limbs	0.125	0.875
H55-H59 Other disorders of eye and adnexa	0.125	0.875
H46-H48 Disorders of optic nerve and visual pathways	0.125	0.875
H10-H13 Disorders of conjunctiva	0.125	0.875
T36-T50 Poisoning by drugs, medicaments and biological substances	0.125	0.875
H90-H95 Other disorders of ear	0.124	0.876
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.124	0.876
J39 Other diseases of upper respiratory tract	0.124	0.876
J37 Chronic laryngitis and laryngotracheitis	0.124	0.876
J36 Peritonsillar abscess	0.124	0.876
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.124	0.876
L91 Hypertrophic disorders of skin	0.124	0.876
L90 Atrophic disorders of skin	0.124	0.876
N10-N16 Renal tubulo-interstitial diseases	0.123	0.876
J30 Vasomotor and allergic rhinitis	0.123	0.877
M19.94 Arthrosis, unspecified (Hand)	0.123	0.877
J44 Other chronic obstructive pulmonary disease	0.123	0.877
M23.3 Other meniscus derangements	0.122	0.878
I69 Sequelae of cerebrovascular disease	0.122	0.878
I80 Phlebitis and thrombophlebitis	0.122	0.878
M45-M49 Spondylopathies	0.122	0.878
M20 Acquired deformities of fingers and toes	0.122	0.878
M19.8 Other specified arthrosis	0.122	0.878
M19.2 Other secondary arthrosis	0.122	0.878
M19.1 Posttraumatic arthrosis of other joints	0.122	0.878
H33 Retinal detachments and breaks	0.121	0.878
J43 Emphysema	0.121	0.879
S82 Fracture of lower leg, including ankle	0.121	0.879
N99-N99 Other disorders of the genitourinary system	0.121	0.879
I05-I09 Chronic rheumatic heart diseases	0.120	0.879
I00-I02 Acute rheumatic fever	0.120	0.879
B95-B98 Bacterial, viral and other infectious agents	0.121	0.879
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.120	0.880
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.119	0.880
T79-T79 Certain early complications of trauma	0.119	0.880
T66-T78 Other and unspecified effects of external causes	0.119	0.880
T33-T35 Frostbite	0.119	0.880
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.119	0.880
T26-T28 Burns and corrosions confined to eye and internal organs	0.119	0.880
T20-T25 Burns and corrosions of external body surface, specified by site	0.119	0.880
T15-T19 Effects of foreign body entering through natural orifice	0.119	0.880
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.119	0.880
T00-T07 Injuries involving multiple body regions	0.119	0.880
S90-S99 Injuries to the ankle and foot	0.119	0.880
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.119	0.880
S10-S19 Injuries to the neck	0.119	0.880
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.119	0.881
L20-L30 Dermatitis and eczema	0.119	0.881
H04.5 Stenosis and insufficiency of lachrymal passages	0.119	0.881
N47 Redundant prepuce, phimosis and paraphimosis	0.119	0.881
J95-J99 Other diseases of the respiratory system	0.119	0.881
J90 Pleural effusion, not elsewhere classified	0.118	0.881
S00-S09 Injuries to the head	0.118	0.882
J69 Pneumonitis due to solids and liquids	0.118	0.882
L82 Seborrhoeic keratosis	0.118	0.882
J32.9 Chronic sinusitis, unspecified	0.118	0.882
F00-F09 Organic, including symptomatic, mental disorders	0.118	0.882
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.118	0.882
M23.9 Internal derangement of knee, unspecified	0.117	0.883
M23.6 Other spontaneous disruption of ligament(s) of knee	0.117	0.883
M23.5 Chronic instability of knee	0.117	0.883
M23.1 Discoid meniscus (congenital)	0.117	0.883
M23.0 Cystic meniscus	0.117	0.883
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.117	0.883
Chapter XV Pregnancy, childbirth and the puerperium	0.117	0.883
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.117	0.883
S70-S79 Injuries to the hip and thigh	0.117	0.883
H60-H62 Diseases of external ear	0.117	0.883
S50-S59 Injuries to the elbow and forearm	0.116	0.884
H25-H28 Disorders of lens	0.116	0.884
B35-B49 Mycoses	0.116	0.884
S40-S49 Injuries to the shoulder and upper arm	0.116	0.884
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.116	0.884
N40 Hyperplasia of prostate	0.115	0.885
N41 Inflammatory diseases of prostate	0.115	0.885
E87 Other disorders of fluid, electrolyte and acid-base balance	0.115	0.885
H18 Other disorders of cornea	0.114	0.885
I95-I99 Other and unspecified disorders of the circulatory system	0.114	0.886
J45.9 Asthma, unspecified	0.114	0.886
L50-L54 Urticaria and erythema	0.114	0.886
L10-L14 Bullous disorders	0.114	0.886
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.114	0.886
I67.9 Cerebrovascular disease, unspecified	0.114	0.886
J84 Other interstitial pulmonary diseases	0.113	0.886
F41 Other anxiety disorders	0.113	0.887
J41 Simple and mucopurulent chronic bronchitis	0.113	0.887
J46 Status asthmaticus	0.113	0.887
J42 Unspecified chronic bronchitis	0.113	0.887
M23.49 Loose body in knee-Unspec lig/men	0.113	0.887
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.113	0.887
M65 Synovitis and tenosynovitis	0.113	0.887
H65-H75 Diseases of middle ear and mastoid	0.113	0.887
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.113	0.887
I88 Nonspecific lymphadenitis	0.113	0.887
I87 Other disorders of veins	0.113	0.887
I86 Varicose veins of other sites	0.113	0.887
I85 Oesophageal varices	0.113	0.887
I82 Other venous embolism and thrombosis	0.113	0.887
I81 Portal vein thrombosis	0.113	0.887
I73 Other peripheral vascular diseases	0.113	0.887
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.112	0.888
N42 Other disorders of prostate	0.112	0.888
H34 Retinal vascular occlusions	0.112	0.888
H32 Chorioretinal disorders in diseases classified elsewhere	0.112	0.888
H31 Other disorders of choroid	0.112	0.888
H30 Chorioretinal inflammation	0.112	0.888
J40 Bronchitis, not specified as acute or chronic	0.112	0.888
L97 Ulcer of lower limb, not elsewhere classified	0.112	0.888
I68 Cerebrovascular disorders in diseases classified elsewhere	0.112	0.888
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.112	0.888
I62 Other nontraumatic intracranial haemorrhage	0.112	0.888
I61 Intracerebral haemorrhage	0.112	0.888
I60 Subarachnoid haemorrhage	0.112	0.888
M19.99 Arthrosis, unspecified (Site unspecified)	0.112	0.888
A30-A49 Other bacterial diseases	0.111	0.889
I74 Arterial embolism and thrombosis	0.111	0.889
H35.3 Degeneration of macula and posterior pole	0.111	0.889
N25-N29 Other disorders of kidney and ureter	0.111	0.889
B25-B34 Other viral diseases	0.111	0.889
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.111	0.889
I83.1 Varicose veins of lower extremities with inflammation	0.111	0.889
I83.0 Varicose veins of lower extremities with ulcer	0.111	0.889
H04.2 Epiphora	0.111	0.889
J70 Respiratory conditions due to other external agents	0.111	0.889
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.111	0.889
J67 Hypersensitivity pneumonitis due to organic dust	0.111	0.889
J66 Airway disease due to specific organic dust	0.111	0.889
J63 Pneumoconiosis due to other inorganic dusts	0.111	0.889
J62 Pneumoconiosis due to dust containing silica	0.111	0.889
J65 Pneumoconiosis associated with tuberculosis	0.111	0.889
J64 Unspecified pneumoconiosis	0.111	0.889
J60 Coalworker's pneumoconiosis	0.111	0.889
H80-H83 Diseases of inner ear	0.110	0.889
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.111	0.889
H01 Other inflammation of eyelid	0.110	0.889
L00-L08 Infections of the skin and subcutaneous tissue	0.110	0.890
F99-F99 Unspecified mental disorder	0.110	0.890
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.110	0.890
F80-F89 Disorders of psychological development	0.110	0.890
F70-F79 Mental retardation	0.110	0.890
F60-F69 Disorders of adult personality and behaviour	0.110	0.890
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.110	0.890
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.110	0.890
H40-H42 Glaucoma	0.110	0.890
B99-B99 Other infectious diseases	0.110	0.890
B90-B94 Sequelae of infectious and parasitic diseases	0.110	0.890
B85-B89 Pediculosis, acariasis and other infestations	0.110	0.890
B65-B83 Helminthiases	0.110	0.890
B50-B64 Protozoal diseases	0.110	0.890
B20-B24 Human immunodeficiency virus [HIV] disease	0.110	0.890
B15-B19 Viral hepatitis	0.110	0.890
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.110	0.890
A80-A89 Viral infections of the central nervous system	0.110	0.890
A75-A79 Rickettsioses	0.110	0.890
A70-A74 Other diseases caused by chlamydiae	0.110	0.890
A65-A69 Other spirochaetal diseases	0.110	0.890
A50-A64 Infections with a predominantly sexual mode of transmission	0.110	0.890
A20-A28 Certain zoonotic bacterial diseases	0.110	0.890
A15-A19 Tuberculosis	0.110	0.890
H36 Retinal disorders in diseases classified elsewhere	0.109	0.890
N30-N39 Other diseases of urinary system	0.109	0.890
J38.3 Other diseases of vocal cords	0.109	0.890
J33 Nasal polyp	0.109	0.890
M19.91 Arthrosis, unspecified (Shoulder region)	0.109	0.891
E83 Disorders of mineral metabolism	0.109	0.891
M19.98 Arthrosis, unspecified (Other)	0.109	0.891
M19.96 Arthrosis, unspecified-Lower leg	0.109	0.891
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.109	0.891
M19.93 Arthrosis, unspecified (Forearm)	0.109	0.891
M19.92 Arthrosis, unspecified (Upper arm)	0.109	0.891
M19.90 Arthrosis, unspecified (Multiple sites)	0.109	0.891
E86 Volume depletion	0.109	0.891
N17.9 Acute renal failure, unspecified	0.109	0.891
J34.3 Hypertrophy of nasal turbinates	0.108	0.891
L81 Other disorders of pigmentation	0.108	0.892
H33.2 Serous retinal detachment	0.108	0.892
L91.8 Other hypertrophic disorders of skin	0.108	0.892
N63 Unspecified lump in breast	0.108	0.892
H00 Hordeolum and chalazion	0.107	0.892
L90.5 Scar conditions and fibrosis of skin	0.107	0.893
N43 Hydrocele and spermatocele	0.107	0.893
A00-A09 Intestinal infectious diseases	0.107	0.893
E50-E64 Other nutritional deficiencies	0.107	0.893
N60 Benign mammary dysplasia	0.107	0.893
M67 Other disorders of synovium and tendon	0.106	0.893
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.106	0.894
H05 Disorders of orbit	0.106	0.894
H03 Disorders of eyelid in diseases classified elsewhere	0.106	0.894
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.106	0.894
J35.8 Other chronic diseases of tonsils and adenoids	0.106	0.894
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.106	0.894
J35.2 Hypertrophy of adenoids	0.106	0.894
J35.0 Chronic tonsillitis	0.106	0.894
J38.7 Other diseases of larynx	0.106	0.894
J38.6 Stenosis of larynx	0.106	0.894
J38.5 Laryngeal spasm	0.106	0.894
J38.4 Oedema of larynx	0.106	0.894
J38.2 Nodules of vocal cords	0.106	0.894
J38.1 Polyp of vocal cord and larynx	0.106	0.894
J47 Bronchiectasis	0.106	0.894
J18 Pneumonia, organism unspecified	0.106	0.894
M25.7 Osteophyte	0.106	0.894
M16 Coxarthrosis [arthrosis of hip]	0.105	0.894
J94 Other pleural conditions	0.105	0.895
J93 Pneumothorax	0.105	0.895
J92 Pleural plaque	0.105	0.895
J91 Pleural effusion in conditions classified elsewhere	0.105	0.895
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.105	0.895
L95 Vasculitis limited to skin, not elsewhere classified	0.105	0.895
L94 Other localised connective tissue disorders	0.105	0.895
L93 Lupus erythematosus	0.105	0.895
L92 Granulomatous disorders of skin and subcutaneous tissue	0.105	0.895
L89 Decubitus ulcer	0.105	0.895
L87 Transepidermal elimination disorders	0.105	0.895
L85 Other epidermal thickening	0.105	0.895
L88 Pyoderma gangrenosum	0.105	0.895
L86 Keratoderma in diseases classified elsewhere	0.105	0.895
L84 Corns and callosities	0.105	0.895
L83 Acanthosis nigricans	0.105	0.895
L80 Vitiligo	0.105	0.895
I77 Other disorders of arteries and arterioles	0.105	0.895
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.105	0.895
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.105	0.895
N51 Disorders of male genital organs in diseases classified elsewhere	0.105	0.895
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.105	0.895
N48 Other disorders of penis	0.105	0.895
N46 Male infertility	0.105	0.895
N44 Torsion of testis	0.105	0.895
F30-F39 Mood [affective] disorders	0.105	0.895
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.104	0.895
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.104	0.896
M66 Spontaneous rupture of synovium and tendon	0.104	0.896
L40-L45 Papulosquamous disorders	0.104	0.896
L60-L75 Disorders of skin appendages	0.104	0.896
M06 Other rheumatoid arthritis	0.104	0.896
S68 Traumatic amputation of wrist and hand	0.103	0.896
S22 Fracture of rib(s), sternum and thoracic spine	0.103	0.897
H91 Other hearing loss	0.103	0.897
J82 Pulmonary eosinophilia, not elsewhere classified	0.103	0.897
J81 Pulmonary oedema	0.103	0.897
J80 Adult respiratory distress syndrome	0.103	0.897
I63.8 Other cerebral infarction	0.103	0.897
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.103	0.897
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.103	0.897
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.103	0.897
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.103	0.897
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.103	0.897
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.103	0.897
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.103	0.897
S64 Injury of nerves at wrist and hand level	0.102	0.897
S62 Fracture at wrist and hand level	0.102	0.898
H35.9 Retinal disorder, unspecified	0.101	0.898
H35.7 Separation of retinal layers	0.101	0.898
H35.6 Retinal haemorrhage	0.101	0.898
H35.5 Hereditary retinal dystrophy	0.101	0.898
H35.4 Peripheral retinal degeneration	0.101	0.898
H35.2 Other proliferative retinopathy	0.101	0.898
H35.1 Retinopathy of prematurity	0.101	0.898
H35.0 Background retinopathy and retinal vascular changes	0.101	0.898
N70-N77 Inflammatory diseases of female pelvic organs	0.101	0.898
M19.09 Primary arthrosis of other joints (Site unspecified)	0.101	0.899
M19.08 Primary arthrosis of other joints (Other)	0.101	0.899
M19.06 Primary arthrosis of other joints-Lower leg	0.101	0.899
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.101	0.899
M19.04 Primary arthrosis of other joints (Hand)	0.101	0.899
M19.03 Primary arthrosis of other joints (Forearm)	0.101	0.899
M19.02 Primary arthrosis of other joints (Upper arm)	0.101	0.899
M19.01 Primary arthrosis of other joints (Shoulder region)	0.101	0.899
M19.00 Primary arthrosis of other joints (Multiple sites)	0.101	0.899
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.101	0.899
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.101	0.899
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.101	0.899
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.101	0.899
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.101	0.899
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.101	0.899
J32.8 Other chronic sinusitis	0.101	0.899
J32.4 Chronic pansinusitis	0.101	0.899
J32.3 Chronic sphenoidal sinusitis	0.101	0.899
J32.2 Chronic ethmoidal sinusitis	0.101	0.899
J32.1 Chronic frontal sinusitis	0.101	0.899
J32.0 Chronic maxillary sinusitis	0.101	0.899
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.101	0.899
I72 Other aneurysm	0.101	0.899
I70 Atherosclerosis	0.101	0.899
I78 Diseases of capillaries	0.101	0.899
E87.7 Fluid overload	0.101	0.899
N20 Calculus of kidney and ureter	0.101	0.899
S89 Other and unspecified injuries of lower leg	0.100	0.899
S88 Traumatic amputation of lower leg	0.100	0.899
S87 Crushing injury of lower leg	0.100	0.899
S86 Injury of muscle and tendon at lower leg level	0.100	0.899
S85 Injury of blood vessels at lower leg level	0.100	0.899
S84 Injury of nerves at lower leg level	0.100	0.899
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.100	0.899
S81 Open wound of lower leg	0.100	0.899
S80 Superficial injury of lower leg	0.100	0.899
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.100	0.900
E40-E46 Malnutrition	0.100	0.900
E20-E35 Disorders of other endocrine glands	0.100	0.900
M43 Other deforming dorsopathies	0.100	0.900
F41.9 Anxiety disorder, unspecified	0.100	0.900
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.100	0.900
H21 Other disorders of iris and ciliary body	0.100	0.900
H20 Iridocyclitis	0.100	0.900
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.100	0.900
H17 Corneal scars and opacities	0.100	0.900
H16 Keratitis	0.100	0.900
H15 Disorders of sclera	0.100	0.900
J17 Pneumonia in diseases classified elsewhere	0.100	0.900
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.100	0.900
J15 Bacterial pneumonia, not elsewhere classified	0.100	0.900
J12 Viral pneumonia, not elsewhere classified	0.100	0.900
J11 Influenza, virus not identified	0.100	0.900
J10 Influenza due to identified influenza virus	0.100	0.900
J14 Pneumonia due to Haemophilus influenzae	0.100	0.900
J13 Pneumonia due to Streptococcus pneumoniae	0.100	0.900
J09 Influenza due to certain identified influenza virus	0.100	0.900
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.100	0.900
N45 Orchitis and epididymitis	0.100	0.900
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.100	0.900
M20.6 Acquired deformity of toe(s), unspecified	0.099	0.900
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.099	0.901
J34.2 Deviated nasal septum	0.099	0.901
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.099	0.901
Y95 Nosocomial condition	0.099	0.901
N18.9 Chronic renal failure, unspecified	0.099	0.901
I71 Aortic aneurysm and dissection	0.098	0.901
T85 Complications of other internal prosthetic devices, implants and grafts	0.098	0.901
M13 Other arthritis	0.098	0.901
M42 Spinal osteochondrosis	0.098	0.902
M41 Scoliosis	0.098	0.902
M40 Kyphosis and lordosis	0.098	0.902
S82.8 Fractures of other parts of lower leg	0.098	0.902
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.098	0.902
M14 Arthropathies in other diseases classified elsewhere	0.098	0.902
M12 Other specific arthropathies	0.098	0.902
M11 Other crystal arthropathies	0.098	0.902
M09 Juvenile arthritis in diseases classified elsewhere	0.098	0.902
M08 Juvenile arthritis	0.098	0.902
M07 Psoriatic and enteropathic arthropathies	0.098	0.902
M05 Seropositive rheumatoid arthritis	0.098	0.902
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.098	0.902
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.097	0.903
Y60-Y69 Misadventures to patients during surgical and medical care	0.097	0.903
Y35-Y36 Legal intervention and operations of war	0.097	0.903
Y10-Y34 Event of undetermined intent	0.097	0.903
Y00-Y09 Assault	0.097	0.903
X85-X99 Assault	0.097	0.903
X60-X84 Intentional self-harm	0.097	0.903
X58-X59 Accidental exposure to other and unspecified factors	0.097	0.903
X50-X57 Overexertion, travel and privation	0.097	0.903
X40-X49 Accidental poisoning by and exposure to noxious substances	0.097	0.903
X30-X39 Exposure to forces of nature	0.097	0.903
X20-X29 Contact with venomous animals and plants	0.097	0.903
X10-X19 Contact with heat and hot substances	0.097	0.903
X00-X09 Exposure to smoke, fire and flames	0.097	0.903
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.097	0.903
W75-W84 Other accidental threats to breathing	0.097	0.903
W65-W74 Accidental drowning and submersion	0.097	0.903
W50-W64 Exposure to animate mechanical forces	0.097	0.903
W20-W49 Exposure to inanimate mechanical forces	0.097	0.903
V98-V99 Other and unspecified transport accidents	0.097	0.903
V95-V97 Air and space transport accidents	0.097	0.903
V90-V94 Water transport accidents	0.097	0.903
V80-V89 Other land transport accidents	0.097	0.903
V70-V79 Bus occupant injured in transport accident	0.097	0.903
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.097	0.903
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.097	0.903
V40-V49 Car occupant injured in transport accident	0.097	0.903
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.097	0.903
V20-V29 Motorcycle rider injured in transport accident	0.097	0.903
V10-V19 Pedal cyclist injured in transport accident	0.097	0.903
V01-V09 Pedestrian injured in transport accident	0.097	0.903
N18.3 Chronic kidney disease, stage 3	0.097	0.903
N64 Other disorders of breast	0.097	0.903
N61 Inflammatory disorders of breast	0.097	0.903
H53 Visual disturbances	0.097	0.903
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.097	0.903
M02 Reactive arthropathies	0.097	0.903
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.097	0.903
M00 Pyogenic arthritis	0.097	0.903
M63 Disorders of muscle in diseases classified elsewhere	0.097	0.903
M62 Other disorders of muscle	0.097	0.903
M61 Calcification and ossification of muscle	0.097	0.903
M60 Myositis	0.097	0.903
M90 Osteopathies in diseases classified elsewhere	0.097	0.903
M89 Other disorders of bone	0.097	0.903
M88 Paget's disease of bone [osteitis deformans]	0.097	0.903
M87 Osteonecrosis	0.097	0.903
M86 Osteomyelitis	0.097	0.903
M94 Other disorders of cartilage	0.097	0.903
M93 Other osteochondropathies	0.097	0.903
M92 Other juvenile osteochondrosis	0.097	0.903
M91 Juvenile osteochondrosis of hip and pelvis	0.097	0.903
M99 Biomechanical lesions, not elsewhere classified	0.097	0.903

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations