TreeWAS – Variant ID: rs12632235

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
M15-M19 Arthrosis	0.996	0.004
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.989	0.011
Chapter XV Pregnancy, childbirth and the puerperium	0.989	0.011
Chapter VII Diseases of the eye and adnexa	0.987	0.013
Chapter V Mental and behavioural disorders	0.983	0.017
M16 Coxarthrosis [arthrosis of hip]	0.980	0.020
M45-M49 Spondylopathies	0.978	0.022
M20-M25 Other joint disorders	0.977	0.023
M16.1 Other primary coxarthrosis	0.974	0.026
Chapter IV Endocrine, nutritional and metabolic diseases	0.970	0.030
E10-E14 Diabetes mellitus	0.969	0.031
E10 Insulin-dependent diabetes mellitus	0.968	0.032
Chapter VIII Diseases of the ear and mastoid process	0.962	0.038
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.957	0.043
H30-H36 Disorders of choroid and retina	0.953	0.047
M47 Spondylosis	0.949	0.051
M47.8 Other spondylosis	0.936	0.064
E10.9 Without complications	0.934	0.066
M18 Arthrosis of first carpometacarpal joint	0.917	0.083
F30-F39 Mood [affective] disorders	0.915	0.085
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.911	0.089
H65-H75 Diseases of middle ear and mastoid	0.903	0.097
F00-F09 Organic, including symptomatic, mental disorders	0.900	0.100
O20-O29 Other maternal disorders predominantly related to pregnancy	0.891	0.109
S00-S09 Injuries to the head	0.890	0.110
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.889	0.111
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.886	0.114
Chapter II Neoplasms	0.886	0.114
E10.3 With ophthalmic complications	0.882	0.118
H43-H45 Disorders of vitreous body and globe	0.879	0.121
M47.82 Other spondylosis (Cervical region)	0.878	0.122
M17 Gonarthrosis [arthrosis of knee]	0.877	0.123
H35 Other retinal disorders	0.875	0.125
M48 Other spondylopathies	0.868	0.132
H80-H83 Diseases of inner ear	0.865	0.135
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.859	0.141
M22 Disorders of patella	0.854	0.146
H33 Retinal detachments and breaks	0.853	0.147
C15-C26 Malignant neoplasms of digestive organs	0.850	0.150
D70-D77 Other diseases of blood and blood-forming organs	0.848	0.152
H10-H13 Disorders of conjunctiva	0.846	0.154
S60-S69 Injuries to the wrist and hand	0.844	0.156
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.841	0.159
M47.80 Other spondylosis (Multiple sites in spine)	0.841	0.159
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.839	0.161
M05-M14 Inflammatory polyarthropathies	0.838	0.162
E10.5 With peripheral circulatory complications	0.837	0.163
F31 Bipolar affective disorder	0.829	0.171
O60-O75 Complications of labour and delivery	0.829	0.171
E10.4 With neurological complications	0.826	0.174
Chapter XIV Diseases of the genitourinary system	0.825	0.175
H65 Nonsuppurative otitis media	0.824	0.176
M35 Other systemic involvement of connective tissue	0.822	0.178
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.822	0.178
M47.87 Other spondylosis (Lumbosacral region)	0.820	0.180
M86-M90 Other osteopathies	0.820	0.180
M23 Internal derangement of knee	0.820	0.180
S40-S49 Injuries to the shoulder and upper arm	0.816	0.183
M40-M43 Deforming dorsopathies	0.814	0.186
M31 Other necrotising vasculopathies	0.807	0.193
H43 Disorders of vitreous body	0.806	0.194
M16.0 Primary coxarthrosis, bilateral	0.803	0.196
M80-M85 Disorders of bone density and structure	0.802	0.198
Chapter XXII Codes for special purposes	0.802	0.198
F40-F48 Neurotic, stress-related and somatoform disorders	0.800	0.200
F05 Delirium, not induced by alcohol and other psychoactive substances	0.798	0.202
O46 Antepartum haemorrhage, not elsewhere classified	0.794	0.206
E10.2 With renal complications	0.794	0.206
M22.4 Chondromalacia patellae	0.793	0.207
M48.0 Spinal stenosis	0.789	0.211
O94-O99 Other obstetric conditions, not elsewhere classified	0.786	0.214
D69 Purpura and other haemorrhagic conditions	0.786	0.214
S09 Other and unspecified injuries of head	0.782	0.218
E10.1 With ketoacidosis	0.780	0.220
H33.3 Retinal breaks without detachment	0.779	0.221
H81 Disorders of vestibular function	0.777	0.222
H71 Cholesteatoma of middle ear	0.777	0.223
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.777	0.223
M17.0 Primary gonarthrosis, bilateral	0.777	0.223
T20-T25 Burns and corrosions of external body surface, specified by site	0.775	0.224
M21 Other acquired deformities of limbs	0.773	0.227
H36 Retinal disorders in diseases classified elsewhere	0.772	0.228
M17.1 Other primary gonarthrosis	0.772	0.228
O16 Unspecified maternal hypertension	0.771	0.229
M91-M94 Chondropathies	0.771	0.229
D68 Other coagulation defects	0.771	0.229
S01 Open wound of head	0.766	0.234
E14 Unspecified diabetes mellitus	0.766	0.234
T66-T78 Other and unspecified effects of external causes	0.764	0.236
N40-N51 Diseases of male genital organs	0.764	0.236
O20 Haemorrhage in early pregnancy	0.764	0.236
H35.0 Background retinopathy and retinal vascular changes	0.763	0.237
F32 Depressive episode	0.762	0.237
H35.6 Retinal haemorrhage	0.762	0.238
C64-C68 Malignant neoplasms of urinary tract	0.760	0.240
O21 Excessive vomiting in pregnancy	0.753	0.247
S90-S99 Injuries to the ankle and foot	0.751	0.249
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.749	0.251
H65.3 Chronic mucoid otitis media	0.749	0.251
T79-T79 Certain early complications of trauma	0.748	0.252
S50-S59 Injuries to the elbow and forearm	0.746	0.254
C19 Malignant neoplasm of rectosigmoid junction	0.745	0.255
M06 Other rheumatoid arthritis	0.743	0.257
O32 Maternal care for known or suspected malpresentation of foetus	0.742	0.258
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.742	0.258
H25-H28 Disorders of lens	0.741	0.258
Chapter XX External causes of morbidity and mortality	0.741	0.259
M24 Other specific joint derangements	0.740	0.260
M25 Other joint disorders, not elsewhere classified	0.740	0.260
S20-S29 Injuries to the thorax	0.739	0.261
F03 Unspecified dementia	0.738	0.261
Chapter VI Diseases of the nervous system	0.735	0.265
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.735	0.265
F31.0 Bipolar affective disorder, current episode hypomanic	0.734	0.266
O42 Premature rupture of membranes	0.732	0.268
T15-T19 Effects of foreign body entering through natural orifice	0.731	0.269
D75 Other diseases of blood and blood-forming organs	0.730	0.270
H46-H48 Disorders of optic nerve and visual pathways	0.727	0.272
F05.9 Delirium, unspecified	0.725	0.275
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.725	0.275
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.724	0.275
O80-O84 Delivery	0.724	0.276
H11 Other disorders of conjunctiva	0.722	0.277
M23.3 Other meniscus derangements	0.722	0.278
O47 False labour	0.720	0.280
H35.4 Peripheral retinal degeneration	0.720	0.280
H81.1 Benign paroxysmal vertigo	0.720	0.280
M35.3 Polymyalgia rheumatica	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
N40 Hyperplasia of prostate	0.715	0.285
M50-M54 Other dorsopathies	0.715	0.285
M15 Polyarthrosis	0.714	0.286
N30-N39 Other diseases of urinary system	0.712	0.288
O46.9 Antepartum haemorrhage, unspecified	0.711	0.289
O63 Long labour	0.711	0.289
C18 Malignant neoplasm of colon	0.711	0.289
D37-D48 Neoplasms of uncertain or unknown behaviour	0.711	0.289
D80-D89 Certain disorders involving the immune mechanism	0.710	0.290
T33-T35 Frostbite	0.709	0.291
T26-T28 Burns and corrosions confined to eye and internal organs	0.709	0.291
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.709	0.291
T00-T07 Injuries involving multiple body regions	0.709	0.291
S10-S19 Injuries to the neck	0.709	0.291
O85-O92 Complications predominantly related to the puerperium	0.709	0.291
S01.0 Open wound of scalp	0.709	0.291
H50 Other strabismus	0.709	0.291
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.708	0.292
D60-D64 Aplastic and other anaemias	0.707	0.293
F99-F99 Unspecified mental disorder	0.707	0.293
S80-S89 Injuries to the knee and lower leg	0.705	0.295
S62 Fracture at wrist and hand level	0.705	0.295
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.705	0.295
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.704	0.295
F80-F89 Disorders of psychological development	0.704	0.295
F70-F79 Mental retardation	0.704	0.295
F60-F69 Disorders of adult personality and behaviour	0.704	0.295
S09.9 Unspecified injury of head	0.704	0.296
M16.7 Other secondary coxarthrosis	0.702	0.298
M16.6 Other secondary coxarthrosis, bilateral	0.702	0.298
M16.5 Other posttraumatic coxarthrosis	0.702	0.298
M16.4 Posttraumatic coxarthrosis, bilateral	0.702	0.298
M16.3 Other dysplastic coxarthrosis	0.702	0.298
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.702	0.298
S70-S79 Injuries to the hip and thigh	0.702	0.298
N50 Other disorders of male genital organs	0.702	0.298
M49 Spondylopathies in diseases classified elsewhere	0.701	0.299
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.700	0.300
M34 Systemic sclerosis	0.700	0.300
M33 Dermatopolymyositis	0.700	0.300
M32 Systemic lupus erythematosus	0.700	0.300
M30 Polyarteritis nodosa and related conditions	0.700	0.300
H43.3 Other vitreous opacities	0.699	0.301
H35.7 Separation of retinal layers	0.699	0.301
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.696	0.304
H55-H59 Other disorders of eye and adnexa	0.696	0.304
E13 Other specified diabetes mellitus	0.695	0.305
E12 Malnutrition-related diabetes mellitus	0.695	0.305
D69.3 Idiopathic thrombocytopenic purpura	0.695	0.305
E10.8 With unspecified complications	0.694	0.306
E10.7 With multiple complications	0.694	0.306
E10.6 With other specified complications	0.694	0.306
E10.0 With coma	0.694	0.306
D70 Agranulocytosis	0.694	0.306
H43.1 Vitreous haemorrhage	0.694	0.306
C16 Malignant neoplasm of stomach	0.692	0.308
O72 Postpartum haemorrhage	0.692	0.308
E40-E46 Malnutrition	0.691	0.309
F41 Other anxiety disorders	0.690	0.310
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.689	0.311
E11 Non-insulin-dependent diabetes mellitus	0.688	0.312
M48.09 Spinal stenosis (Site unspecified)	0.688	0.312
M89 Other disorders of bone	0.687	0.313
D55-D59 Haemolytic anaemias	0.686	0.314
D68.9 Coagulation defect, unspecified	0.686	0.314
C51-C58 Malignant neoplasms of female genital organs	0.684	0.315
H32 Chorioretinal disorders in diseases classified elsewhere	0.683	0.317
H31 Other disorders of choroid	0.683	0.317
H30 Chorioretinal inflammation	0.683	0.317
S31 Open wound of abdomen, lower back and pelvis	0.683	0.317
H33.2 Serous retinal detachment	0.682	0.318
E20-E35 Disorders of other endocrine glands	0.681	0.318
M06.9 Rheumatoid arthritis, unspecified	0.681	0.319
N60-N64 Disorders of breast	0.681	0.319
M47.1 Other spondylosis with myelopathy	0.680	0.320
M47.0 Anterior spinal and vertebral artery compression syndromes	0.680	0.320
O43 Placental disorders	0.680	0.320
M48.06 Spinal stenosis (Lumbar region)	0.680	0.320
T36-T50 Poisoning by drugs, medicaments and biological substances	0.680	0.320
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.680	0.320
O23 Infections of genito-urinary tract in pregnancy	0.679	0.320
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.678	0.322
M47.89 Other spondylosis (Site unspecified)	0.677	0.323
M47.2 Other spondylosis with radiculopathy	0.676	0.324
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.675	0.325
M23.8 Other internal derangements of knee	0.675	0.325
S60 Superficial injury of wrist and hand	0.674	0.326
H83 Other diseases of inner ear	0.672	0.328
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.671	0.329
M47.85 Other spondylosis (Thoracolumbar region)	0.671	0.329
M47.84 Other spondylosis (Thoracic region)	0.671	0.329
M47.83 Other spondylosis (Cervicothoracic region)	0.671	0.329
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.671	0.329
F33 Recurrent depressive disorder	0.670	0.330
S06 Intracranial injury	0.667	0.333
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.666	0.334
H72 Perforation of tympanic membrane	0.665	0.335
C64 Malignant neoplasm of kidney, except renal pelvis	0.664	0.336
M43 Other deforming dorsopathies	0.664	0.336
O75 Other complications of labour and delivery, not elsewhere classified	0.664	0.336
O41 Other disorders of amniotic fluid and membranes	0.663	0.337
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.663	0.337
M23.4 Loose body in knee	0.663	0.337
H65.4 Other chronic nonsuppurative otitis media	0.663	0.337
H60-H62 Diseases of external ear	0.663	0.337
S32 Fracture of lumbar spine and pelvis	0.662	0.338
M17.3 Other posttraumatic gonarthrosis	0.661	0.339
F32.9 Depressive episode, unspecified	0.661	0.339
N50.8 Other specified disorders of male genital organs	0.660	0.340
M47.86 Other spondylosis (Lumbar region)	0.659	0.341
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.659	0.341
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.659	0.341
M54 Dorsalgia	0.658	0.342
O34 Maternal care for known or suspected abnormality of pelvic organs	0.658	0.342
M46 Other inflammatory spondylopathies	0.658	0.342
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.658	0.342
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.657	0.342
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.657	0.342
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.657	0.342
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.657	0.342
O61 Failed induction of labour	0.657	0.343
M25.8 Other specified joint disorders	0.657	0.343
F38 Other mood [affective] disorders	0.656	0.344
F34 Persistent mood [affective] disorders	0.656	0.344
F30 Manic episode	0.656	0.344
F39 Unspecified mood [affective] disorder	0.656	0.344
S66 Injury of muscle and tendon at wrist and hand level	0.656	0.344
O36 Maternal care for other known or suspected foetal problems	0.654	0.346
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.653	0.346
O45 Premature separation of placenta [abruptio placentae]	0.653	0.347
O44 Placenta praevia	0.653	0.347
O35 Maternal care for known or suspected foetal abnormality and damage	0.653	0.347
O33 Maternal care for known or suspected disproportion	0.653	0.347
O31 Complications specific to multiple gestation	0.653	0.347
O40 Polyhydramnios	0.653	0.347
C22.1 Intrahepatic bile duct carcinoma	0.653	0.347
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.653	0.347
F20 Schizophrenia	0.652	0.348
M45 Ankylosing spondylitis	0.652	0.348
S67 Crushing injury of wrist and hand	0.651	0.349
F00 Dementia in Alzheimer's disease	0.649	0.350
F31.9 Bipolar affective disorder, unspecified	0.649	0.351
H10 Conjunctivitis	0.649	0.351
H49 Paralytic strabismus	0.649	0.351
M05 Seropositive rheumatoid arthritis	0.649	0.351
N25-N29 Other disorders of kidney and ureter	0.648	0.352
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.647	0.353
H74 Other disorders of middle ear and mastoid	0.647	0.353
H70 Mastoiditis and related conditions	0.647	0.353
H69 Other disorders of Eustachian tube	0.647	0.353
H68 Eustachian salpingitis and obstruction	0.647	0.353
H67 Otitis media in diseases classified elsewhere	0.647	0.353
D75.1 Secondary polycythaemia	0.647	0.353
M31.6 Other giant cell arteritis	0.646	0.354
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.646	0.354
F02 Dementia in other diseases classified elsewhere	0.646	0.354
F01 Vascular dementia	0.646	0.354
F09 Unspecified organic or symptomatic mental disorder	0.646	0.354
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.646	0.354
H90-H95 Other disorders of ear	0.644	0.355
M18.1 Other primary arthrosis of first carpometacarpal joint	0.643	0.356
M80 Osteoporosis with pathological fracture	0.643	0.357
H36.0 Diabetic retinopathy	0.643	0.357
D72 Other disorders of white blood cells	0.642	0.358
O20.9 Haemorrhage in early pregnancy, unspecified	0.642	0.358
O30 Multiple gestation	0.640	0.359
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.640	0.360
S30 Superficial injury of abdomen, lower back and pelvis	0.639	0.360
O29 Complications of anaesthesia during pregnancy	0.639	0.361
O28 Abnormal findings on antenatal screening of mother	0.639	0.361
O24 Diabetes mellitus in pregnancy	0.639	0.361
O22 Venous complications in pregnancy	0.639	0.361
O25 Malnutrition in pregnancy	0.639	0.361
S08 Traumatic amputation of part of head	0.638	0.362
S07 Crushing injury of head	0.638	0.362
S05 Injury of eye and orbit	0.638	0.362
S04 Injury of cranial nerves	0.638	0.362
S03 Dislocation, sprain and strain of joints and ligaments of head	0.638	0.362
N70-N77 Inflammatory diseases of female pelvic organs	0.638	0.362
D67 Hereditary factor IX deficiency	0.637	0.363
D66 Hereditary factor VIII deficiency	0.637	0.363
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.637	0.363
M84 Disorders of continuity of bone	0.636	0.364
H73 Other disorders of tympanic membrane	0.636	0.364
O15 Eclampsia	0.635	0.365
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.635	0.365
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.635	0.365
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.635	0.365
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.635	0.365
C40-C41 Malignant neoplasms of bone and articular cartilage	0.635	0.365
M31.3 Wegener's granulomatosis	0.634	0.366
F29 Unspecified nonorganic psychosis	0.633	0.367
C32 Malignant neoplasm of larynx	0.633	0.367
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.633	0.367
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.632	0.368
H33.5 Other retinal detachments	0.632	0.368
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.632	0.368
O21.9 Vomiting of pregnancy, unspecified	0.631	0.369
N39 Other disorders of urinary system	0.631	0.369
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.630	0.369
E14.9 Without complications	0.629	0.371
M17.5 Other secondary gonarthrosis	0.629	0.371
M17.4 Other secondary gonarthrosis, bilateral	0.629	0.371
M17.2 Posttraumatic gonarthrosis, bilateral	0.629	0.371
N00-N08 Glomerular diseases	0.628	0.372
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.628	0.372
F22 Persistent delusional disorders	0.628	0.372
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.628	0.372
H35.9 Retinal disorder, unspecified	0.627	0.373
H35.5 Hereditary retinal dystrophy	0.627	0.373
H35.2 Other proliferative retinopathy	0.627	0.373
H35.1 Retinopathy of prematurity	0.627	0.373
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.627	0.373
M21.3 Wrist or foot drop (acquired)	0.627	0.373
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.625	0.375
M20 Acquired deformities of fingers and toes	0.624	0.376
E50-E64 Other nutritional deficiencies	0.623	0.377
T20 Burn and corrosion of head and neck	0.622	0.378
M48.9 Spondylopathy, unspecified	0.622	0.378
M48.8 Other specified spondylopathies	0.622	0.378
M48.5 Collapsed vertebra, not elsewhere classified	0.622	0.378
M48.4 Fatigue fracture of vertebra	0.622	0.378
M48.3 Traumatic spondylopathy	0.622	0.378
M48.2 Kissing spine	0.622	0.378
M48.1 Ankylosing hyperostosis [Forestier]	0.622	0.378
O32.1 Maternal care for breech presentation	0.622	0.378
E11.4 With neurological complications	0.621	0.379
C56 Malignant neoplasm of ovary	0.621	0.379
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.621	0.379
H80 Otosclerosis	0.620	0.379
H82 Vertiginous syndromes in diseases classified elsewhere	0.620	0.379
M25.7 Osteophyte	0.620	0.380
S40 Superficial injury of shoulder and upper arm	0.620	0.380
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.619	0.381
S46 Injury of muscle and tendon at shoulder and upper arm level	0.619	0.381
W00-W19 Falls	0.619	0.381
H44 Disorders of globe	0.618	0.382
N42 Other disorders of prostate	0.617	0.383
O66 Other obstructed labour	0.616	0.384
H34 Retinal vascular occlusions	0.613	0.386
M22.1 Recurrent subluxation of patella	0.612	0.387
M22.9 Disorder of patella, unspecified	0.612	0.387
M22.3 Other derangements of patella	0.612	0.387
M22.0 Recurrent dislocation of patella	0.612	0.387
H11.0 Pterygium	0.612	0.388
O72.2 Delayed and secondary postpartum haemorrhage	0.612	0.388
C15 Malignant neoplasm of oesophagus	0.612	0.388
H33.4 Traction detachment of retina	0.611	0.389
H33.1 Retinoschisis and retinal cysts	0.611	0.389
H66 Suppurative and unspecified otitis media	0.611	0.389
C26 Malignant neoplasm of other and ill-defined digestive organs	0.609	0.391
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.609	0.391
C21 Malignant neoplasm of anus and anal canal	0.609	0.391
C17 Malignant neoplasm of small intestine	0.609	0.391
C23 Malignant neoplasm of gallbladder	0.609	0.391
H52 Disorders of refraction and accommodation	0.608	0.392
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.608	0.392
D74 Methaemoglobinaemia	0.608	0.392
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.608	0.392
D71 Functional disorders of polymorphonuclear neutrophils	0.608	0.392
M41 Scoliosis	0.608	0.392
Chapter XII Diseases of the skin and subcutaneous tissue	0.607	0.393
M86 Osteomyelitis	0.607	0.393
M94 Other disorders of cartilage	0.607	0.393
H13 Disorders of conjunctiva in diseases classified elsewhere	0.606	0.393
M48.07 Spinal stenosis (Lumbosacral region)	0.606	0.394
F32.3 Severe depressive episode with psychotic symptoms	0.605	0.395
S69 Other and unspecified injuries of wrist and hand	0.605	0.395
S65 Injury of blood vessels at wrist and hand level	0.605	0.395
D69.6 Thrombocytopenia, unspecified	0.605	0.395
N43 Hydrocele and spermatocele	0.603	0.397
T78 Adverse effects, not elsewhere classified	0.603	0.397
H51 Other disorders of binocular movement	0.603	0.397
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.603	0.397
C18.9 Colon, unspecified	0.602	0.398
T91 Sequelae of injuries of neck and trunk	0.602	0.398
O20.0 Threatened abortion	0.601	0.398
O42.9 Premature rupture of membranes, unspecified	0.601	0.398
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.601	0.399
S37 Injury of urinary and pelvic organs	0.601	0.399
S36 Injury of intra-abdominal organs	0.601	0.399
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.601	0.399
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.601	0.399
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.601	0.399
M14 Arthropathies in other diseases classified elsewhere	0.601	0.399
M12 Other specific arthropathies	0.601	0.399
M09 Juvenile arthritis in diseases classified elsewhere	0.601	0.399
M08 Juvenile arthritis	0.601	0.399
G63 Polyneuropathy in diseases classified elsewhere	0.601	0.399
O69 Labour and delivery complicated by umbilical cord complications	0.601	0.399
H25 Senile cataract	0.599	0.401
M07 Psoriatic and enteropathic arthropathies	0.598	0.402
C20 Malignant neoplasm of rectum	0.597	0.402
S01.2 Open wound of nose	0.597	0.403
S62.3 Fracture of other metacarpal bone	0.596	0.404
T90 Sequelae of injuries of head	0.596	0.404
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.596	0.404
O64 Obstructed labour due to malposition and malpresentation of foetus	0.595	0.405
S61 Open wound of wrist and hand	0.594	0.406
F31.8 Other bipolar affective disorders	0.594	0.406
F31.7 Bipolar affective disorder, currently in remission	0.594	0.406
F31.6 Bipolar affective disorder, current episode mixed	0.594	0.406
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.594	0.406
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.594	0.406
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.594	0.406
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.594	0.406
O74 Complications of anaesthesia during labour and delivery	0.594	0.406
O73 Retained placenta and membranes, without haemorrhage	0.594	0.406
O71 Other obstetric trauma	0.594	0.406
O65 Obstructed labour due to maternal pelvic abnormality	0.594	0.406
O60 Preterm delivery	0.594	0.406
O63.1 Prolonged second stage (of labour)	0.594	0.406
M23.5 Chronic instability of knee	0.593	0.407
N17-N19 Renal failure	0.593	0.407
M25.6 Stiffness of joint, not elsewhere classified	0.593	0.407
S00 Superficial injury of head	0.593	0.407
S01.8 Open wound of other parts of head	0.593	0.407
M89.9 Disorder of bone, unspecified	0.592	0.408
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.592	0.408
H65.2 Chronic serous otitis media	0.591	0.409
H65.1 Other acute nonsuppurative otitis media	0.591	0.409
H65.0 Acute serous otitis media	0.591	0.409
M54.5 Low back pain	0.591	0.409
M19 Other arthrosis	0.591	0.409
M35.9 Systemic involvement of connective tissue, unspecified	0.590	0.410
M35.8 Other specified systemic involvement of connective tissue	0.590	0.410
M35.7 Hypermobility syndrome	0.590	0.410
M35.6 Relapsing panniculitis [Weber-Christian]	0.590	0.410
M35.5 Multifocal fibrosclerosis	0.590	0.410
M35.4 Diffuse (eosinophilic) fasciitis	0.590	0.410
M35.2 Behcet's disease	0.590	0.410
M35.1 Other overlap syndromes	0.590	0.410
F25 Schizoaffective disorders	0.589	0.410
F23 Acute and transient psychotic disorders	0.589	0.410
F28 Other nonorganic psychotic disorders	0.589	0.410
F24 Induced delusional disorder	0.589	0.410
F21 Schizotypal disorder	0.589	0.410
F43 Reaction to severe stress, and adjustment disorders	0.589	0.410
O26 Maternal care for other conditions predominantly related to pregnancy	0.588	0.411
M90 Osteopathies in diseases classified elsewhere	0.588	0.412
M87 Osteonecrosis	0.588	0.412
M23.9 Internal derangement of knee, unspecified	0.588	0.412
M23.6 Other spontaneous disruption of ligament(s) of knee	0.588	0.412
M23.1 Discoid meniscus (congenital)	0.588	0.412
M23.0 Cystic meniscus	0.588	0.412
D50-D53 Nutritional anaemias	0.588	0.412
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.588	0.412
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.588	0.412
S49 Other and unspecified injuries of shoulder and upper arm	0.585	0.414
S48 Traumatic amputation of shoulder and upper arm	0.585	0.414
S45 Injury of blood vessels at shoulder and upper arm level	0.585	0.414
S44 Injury of nerves at shoulder and upper arm level	0.585	0.414
S41 Open wound of shoulder and upper arm	0.585	0.414
S47 Crushing injury of shoulder and upper arm	0.585	0.414
O82 Single delivery by Caesarean section	0.585	0.415
M11 Other crystal arthropathies	0.585	0.415
F45 Somatoform disorders	0.584	0.415
F41.9 Anxiety disorder, unspecified	0.584	0.416
M42 Spinal osteochondrosis	0.583	0.417
M40 Kyphosis and lordosis	0.583	0.417
H53-H54 Visual disturbances and blindness	0.583	0.417
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.583	0.417
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.582	0.418
S43.0 Dislocation of shoulder joint	0.582	0.418
M10 Gout	0.582	0.418
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.581	0.419
O21.0 Mild hyperemesis gravidarum	0.581	0.419

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations