TreeWAS – Variant ID: rs12655917

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter VI Diseases of the nervous system	0.930	0.070	0.000
G40-G47 Episodic and paroxysmal disorders	0.929	0.071	0.000
G43 Migraine	0.923	0.077	0.000
G43.9 Migraine, unspecified	0.919	0.081	0.000
G47 Sleep disorders	0.912	0.088	0.000
M45-M49 Spondylopathies	0.906	0.094	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.906	0.094	0.000
G90-G99 Other disorders of the nervous system	0.901	0.099	0.000
M47 Spondylosis	0.887	0.113	0.000
M65-M68 Disorders of synovium and tendon	0.882	0.118	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.873	0.127	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.868	0.132	0.000
M05-M14 Inflammatory polyarthropathies	0.868	0.132	0.000
M48 Other spondylopathies	0.866	0.134	0.000
G47.9 Sleep disorder, unspecified	0.853	0.147	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.852	0.148	0.000
G47.3 Sleep apnoea	0.851	0.149	0.000
M47.9 Spondylosis, unspecified	0.846	0.154	0.000
M48.0 Spinal stenosis	0.840	0.160	0.000
M06 Other rheumatoid arthritis	0.835	0.165	0.000
M65 Synovitis and tenosynovitis	0.835	0.165	0.000
M50-M54 Other dorsopathies	0.827	0.173	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.805	0.195	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.794	0.206	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.792	0.208	0.000
# Top node	0.784	0.216	0.000
M10 Gout	0.780	0.220	0.000
G51 Facial nerve disorders	0.778	0.222	0.000
M47.8 Other spondylosis	0.777	0.223	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.775	0.224	0.000
M06.0 Seronegative rheumatoid arthritis	0.773	0.227	0.000
M67 Other disorders of synovium and tendon	0.773	0.227	0.000
M48.02 Spinal stenosis (Cervical region)	0.770	0.230	0.000
M86-M90 Other osteopathies	0.768	0.232	0.000
G61 Inflammatory polyneuropathy	0.767	0.233	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.763	0.237	0.000
M50 Cervical disk disorders	0.759	0.241	0.000
G96 Other disorders of central nervous system	0.759	0.241	0.000
M48.09 Spinal stenosis (Site unspecified)	0.756	0.244	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.752	0.248	0.000
M45 Ankylosing spondylitis	0.751	0.249	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.751	0.249	0.000
M47.82 Other spondylosis (Cervical region)	0.750	0.250	0.000
M06.9 Rheumatoid arthritis, unspecified	0.742	0.258	0.000
G51.0 Bell's palsy	0.736	0.264	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.724	0.276	0.000
M50.0 Cervical disk disorder with myelopathy	0.721	0.279	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.718	0.282	0.000
M10.9 Gout, unspecified	0.717	0.283	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.710	0.290	0.000
M60-M63 Disorders of muscles	0.707	0.293	0.000
M46 Other inflammatory spondylopathies	0.705	0.294	0.000
M67.8 Other specified disorders of synovium and tendon	0.705	0.295	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.703	0.297	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.703	0.297	0.000
M40-M43 Deforming dorsopathies	0.702	0.297	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.702	0.298	0.000
M47.1 Other spondylosis with myelopathy	0.700	0.300	0.000
G62 Other polyneuropathies	0.694	0.306	0.000
S50-S59 Injuries to the elbow and forearm	0.689	0.311	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.688	0.312	0.000
G90 Disorders of autonomic nervous system	0.687	0.312	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.686	0.314	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.685	0.315	0.000
S10-S19 Injuries to the neck	0.684	0.316	0.000
M48.06 Spinal stenosis (Lumbar region)	0.684	0.316	0.000
G30-G32 Other degenerative diseases of the nervous system	0.683	0.317	0.000
M10.99 Gout, unspecified (Site unspecified)	0.680	0.320	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.679	0.321	0.000
G20-G26 Extrapyramidal and movement disorders	0.671	0.329	0.000
M66 Spontaneous rupture of synovium and tendon	0.671	0.329	0.000
G57 Mononeuropathies of lower limb	0.669	0.331	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.669	0.331	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.667	0.333	0.000
M54 Dorsalgia	0.667	0.333	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.666	0.334	0.000
G60 Hereditary and idiopathic neuropathy	0.665	0.335	0.000
G12 Spinal muscular atrophy and related syndromes	0.665	0.335	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.663	0.337	0.000
G43.8 Other migraine	0.662	0.338	0.000
G43.3 Complicated migraine	0.662	0.338	0.000
G43.2 Status migrainosus	0.662	0.338	0.000
G43.0 Migraine without aura [common migraine]	0.662	0.338	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.660	0.340	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.655	0.345	0.000
G47.4 Narcolepsy and cataplexy	0.654	0.346	0.000
G47.2 Disorders of the sleep-wake schedule	0.654	0.346	0.000
G61.0 Guillain-Barre syndrome	0.653	0.347	0.000
G43.1 Migraine with aura [classical migraine]	0.651	0.349	0.000
M49 Spondylopathies in diseases classified elsewhere	0.650	0.350	0.000
M00-M03 Infectious arthropathies	0.649	0.350	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.648	0.351	0.000
M88 Paget's disease of bone [osteitis deformans]	0.648	0.352	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.647	0.353	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.646	0.354	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.646	0.354	0.000
G92 Toxic encephalopathy	0.646	0.354	0.000
G41 Status epilepticus	0.645	0.355	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.639	0.361	0.000
M65.3 Trigger finger	0.638	0.362	0.000
G47.8 Other sleep disorders	0.637	0.363	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.636	0.364	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.635	0.365	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.635	0.365	0.000
M91-M94 Chondropathies	0.634	0.366	0.000
G51.9 Disorder of facial nerve, unspecified	0.634	0.366	0.000
G44 Other headache syndromes	0.634	0.366	0.000
G70-G73 Diseases of myoneural junction and muscle	0.633	0.367	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.633	0.367	0.000
S00-S09 Injuries to the head	0.633	0.367	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.632	0.368	0.000
M80-M85 Disorders of bone density and structure	0.632	0.368	0.000
G96.0 Cerebrospinal fluid leak	0.632	0.368	0.000
M47.2 Other spondylosis with radiculopathy	0.631	0.369	0.000
S60-S69 Injuries to the wrist and hand	0.629	0.371	0.000
M14 Arthropathies in other diseases classified elsewhere	0.628	0.372	0.000
G61.8 Other inflammatory polyneuropathies	0.628	0.372	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.626	0.374	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.626	0.374	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.626	0.374	0.000
M50.2 Other cervical disk displacement	0.625	0.375	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.623	0.376	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.623	0.377	0.000
G64 Other disorders of peripheral nervous system	0.623	0.377	0.000
M12 Other specific arthropathies	0.622	0.378	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.622	0.378	0.000
M08 Juvenile arthritis	0.622	0.378	0.000
M48.9 Spondylopathy, unspecified	0.621	0.379	0.000
M48.8 Other specified spondylopathies	0.621	0.379	0.000
M48.4 Fatigue fracture of vertebra	0.621	0.379	0.000
M48.3 Traumatic spondylopathy	0.621	0.379	0.000
M48.2 Kissing spine	0.621	0.379	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.621	0.379	0.000
G51.8 Other disorders of facial nerve	0.621	0.379	0.000
S51 Open wound of forearm	0.620	0.380	0.000
G93 Other disorders of brain	0.614	0.386	0.000
M07 Psoriatic and enteropathic arthropathies	0.613	0.387	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.613	0.387	0.000
G95 Other diseases of spinal cord	0.612	0.388	0.000
M06.4 Inflammatory polyarthropathy	0.610	0.390	0.000
M53 Other dorsopathies, not elsewhere classified	0.609	0.391	0.000
T51 Toxic effect of alcohol	0.609	0.391	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.606	0.394	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.606	0.394	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.606	0.394	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.606	0.394	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.606	0.394	0.000
S90-S99 Injuries to the ankle and foot	0.606	0.394	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.605	0.395	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.604	0.396	0.000
T23 Burn and corrosion of wrist and hand	0.603	0.397	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.603	0.397	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.602	0.398	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.602	0.398	0.000
M48.04 Spinal stenosis (Thoracic region)	0.602	0.398	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.602	0.398	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.602	0.398	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.602	0.398	0.000
M54.2 Cervicalgia	0.599	0.401	0.000
M06.8 Other specified rheumatoid arthritis	0.599	0.401	0.000
M06.3 Rheumatoid nodule	0.599	0.401	0.000
M06.2 Rheumatoid bursitis	0.599	0.401	0.000
M06.1 Adult-onset Still's disease	0.599	0.401	0.000
M65.8 Other synovitis and tenosynovitis	0.599	0.401	0.000
M65.2 Calcific tendinitis	0.599	0.401	0.000
M65.1 Other infective (teno)synovitis	0.599	0.401	0.000
M65.0 Abscess of tendon sheath	0.599	0.401	0.000
M11 Other crystal arthropathies	0.597	0.403	0.000
S40-S49 Injuries to the shoulder and upper arm	0.595	0.405	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.593	0.406	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.591	0.408	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.591	0.408	0.000
G91 Hydrocephalus	0.591	0.408	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.591	0.409	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.588	0.412	0.000
M05 Seropositive rheumatoid arthritis	0.587	0.413	0.000
G03 Meningitis due to other and unspecified causes	0.586	0.414	0.000
Chapter XX External causes of morbidity and mortality	0.586	0.414	0.000
G12.2 Motor neuron disease	0.585	0.415	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.584	0.416	0.000
T66-T78 Other and unspecified effects of external causes	0.578	0.422	0.000
G52 Disorders of other cranial nerves	0.577	0.422	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.575	0.425	0.000
M89 Other disorders of bone	0.575	0.425	0.000
G62.9 Polyneuropathy, unspecified	0.574	0.426	0.000
M47.89 Other spondylosis (Site unspecified)	0.573	0.427	0.000
S51.9 Open wound of forearm, part unspecified	0.573	0.427	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.569	0.431	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.569	0.431	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.569	0.431	0.000
G00 Bacterial meningitis, not elsewhere classified	0.569	0.431	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.569	0.431	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.569	0.431	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.569	0.431	0.000
T33-T35 Frostbite	0.568	0.432	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.568	0.432	0.000
T00-T07 Injuries involving multiple body regions	0.568	0.432	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.568	0.432	0.000
S56 Injury of muscle and tendon at forearm level	0.568	0.432	0.000
M87 Osteonecrosis	0.566	0.434	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.565	0.435	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.565	0.435	0.000
S00 Superficial injury of head	0.565	0.435	0.000
M62 Other disorders of muscle	0.564	0.436	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.564	0.436	0.000
S12 Fracture of neck	0.563	0.437	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.562	0.438	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.562	0.438	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.562	0.438	0.000
M88.9 Paget's disease of bone, unspecified	0.561	0.439	0.000
M10.4 Other secondary gout	0.559	0.441	0.000
M10.3 Gout due to impairment of renal function	0.559	0.441	0.000
M10.2 Drug-induced gout	0.559	0.441	0.000
M10.1 Lead-induced gout	0.559	0.441	0.000
M10.0 Idiopathic gout	0.559	0.441	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.558	0.442	0.000
G51.4 Facial myokymia	0.558	0.442	0.000
G51.3 Clonic hemifacial spasm	0.558	0.442	0.000
G51.2 Melkersson's syndrome	0.558	0.442	0.000
G51.1 Geniculate ganglionitis	0.558	0.442	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.557	0.443	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.557	0.443	0.000
M47.84 Other spondylosis (Thoracic region)	0.557	0.443	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.557	0.443	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.557	0.443	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.557	0.443	0.000
G57.6 Lesion of plantar nerve	0.557	0.443	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.556	0.444	0.000
G11 Hereditary ataxia	0.556	0.444	0.000
G14 Postpolio syndrome	0.556	0.444	0.000
G10 Huntington's disease	0.556	0.444	0.000
G63.2 Diabetic polyneuropathy	0.556	0.444	0.000
S19 Other and unspecified injuries of neck	0.555	0.445	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.554	0.446	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.554	0.446	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.554	0.446	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.554	0.446	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.554	0.446	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.554	0.446	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.554	0.446	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.554	0.446	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.554	0.446	0.000
M67.4 Ganglion	0.554	0.446	0.000
M67.3 Transient synovitis	0.554	0.446	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.554	0.446	0.000
M67.0 Short Achilles tendon (acquired)	0.554	0.446	0.000
T51.0 Ethanol	0.553	0.447	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.553	0.447	0.000
M86 Osteomyelitis	0.552	0.447	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.551	0.449	0.000
M90 Osteopathies in diseases classified elsewhere	0.551	0.449	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.550	0.450	0.000
G61.1 Serum neuropathy	0.550	0.450	0.000
Chapter I Certain infectious and parasitic diseases	0.548	0.452	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.547	0.453	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.547	0.453	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.547	0.453	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.547	0.453	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.547	0.453	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.545	0.455	0.000
M50.9 Cervical disk disorder, unspecified	0.544	0.455	0.000
M50.8 Other cervical disk disorders	0.544	0.455	0.000
G96.9 Disorder of central nervous system, unspecified	0.544	0.455	0.000
G96.8 Other specified disorders of central nervous system	0.544	0.455	0.000
M54.9 Dorsalgia, unspecified	0.544	0.456	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.544	0.456	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.542	0.458	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.541	0.459	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.541	0.459	0.000
T93 Sequelae of injuries of lower limb	0.541	0.459	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.539	0.461	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.539	0.461	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.539	0.461	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.539	0.461	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.539	0.461	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.539	0.461	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.539	0.461	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.538	0.462	0.000
T36 Poisoning by systemic antibiotics	0.538	0.462	0.000
G54 Nerve root and plexus disorders	0.537	0.463	0.000
G20 Parkinson's disease	0.535	0.465	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.534	0.466	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.533	0.467	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.533	0.467	0.000
M43 Other deforming dorsopathies	0.532	0.468	0.001
M41 Scoliosis	0.532	0.468	0.000
Chapter XXII Codes for special purposes	0.532	0.468	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.532	0.468	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.532	0.468	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.532	0.468	0.000
G80 Infantile cerebral palsy	0.532	0.468	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.531	0.469	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.530	0.470	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.530	0.470	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.530	0.470	0.000
S70-S79 Injuries to the hip and thigh	0.529	0.471	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.526	0.474	0.000
T17 Foreign body in respiratory tract	0.524	0.476	0.000
T59 Toxic effect of other gases, fumes and vapours	0.524	0.476	0.000
M66.0 Rupture of popliteal cyst	0.520	0.480	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.520	0.480	0.000
M67.1 Other contracture of tendon (sheath)	0.520	0.480	0.000
M51 Other intervertebral disk disorders	0.519	0.481	0.000
G60.0 Hereditary motor and sensory neuropathy	0.519	0.481	0.000
T91 Sequelae of injuries of neck and trunk	0.519	0.481	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.519	0.481	0.000
M54.22 Cervicalgia (Cervical region)	0.518	0.482	0.000
G93.0 Cerebral cysts	0.516	0.484	0.000
S06 Intracranial injury	0.516	0.484	0.000
T18 Foreign body in alimentary tract	0.516	0.484	0.000
T25 Burn and corrosion of ankle and foot	0.515	0.485	0.000
T21 Burn and corrosion of trunk	0.515	0.485	0.000
T20 Burn and corrosion of head and neck	0.515	0.485	0.000
S62 Fracture at wrist and hand level	0.515	0.485	0.000
M10.98 Gout, unspecified (Other)	0.514	0.486	0.000
M10.96 Gout, unspecified (Lower leg)	0.514	0.486	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.514	0.486	0.000
M10.94 Gout, unspecified (Hand)	0.514	0.486	0.000
M10.93 Gout, unspecified (Forearm)	0.514	0.486	0.000
M10.92 Gout, unspecified (Upper arm)	0.514	0.486	0.000
M10.91 Gout, unspecified (Shoulder region)	0.514	0.486	0.000
M10.90 Gout, unspecified (Multiple sites)	0.514	0.486	0.000
M84 Disorders of continuity of bone	0.514	0.486	0.000
S00.1 Contusion of eyelid and periocular area	0.513	0.487	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.512	0.487	0.000
S40 Superficial injury of shoulder and upper arm	0.512	0.488	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.511	0.489	0.000
T87 Complications peculiar to reattachment and amputation	0.510	0.489	0.000
T90 Sequelae of injuries of head	0.510	0.490	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.507	0.493	0.000
M61 Calcification and ossification of muscle	0.507	0.493	0.000
M60 Myositis	0.507	0.493	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.507	0.493	0.000
M46.8 Other specified inflammatory spondylopathies	0.506	0.494	0.000
M46.5 Other infective spondylopathies	0.506	0.494	0.000
M46.4 Discitis, unspecified	0.506	0.494	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.506	0.494	0.000
M46.2 Osteomyelitis of vertebra	0.506	0.494	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.506	0.494	0.000
M46.0 Spinal enthesopathy	0.506	0.494	0.000
G50 Disorders of trigeminal nerve	0.505	0.494	0.000
G57.8 Other mononeuropathies of lower limb	0.505	0.495	0.000
Q00-Q07 Congenital malformations of the nervous system	0.505	0.495	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.504	0.496	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.504	0.496	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.504	0.496	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.504	0.496	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.504	0.496	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.504	0.496	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.504	0.496	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.504	0.496	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.504	0.496	0.000
M42 Spinal osteochondrosis	0.504	0.496	0.000
M40 Kyphosis and lordosis	0.504	0.496	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.504	0.496	0.000
M54.1 Radiculopathy	0.504	0.496	0.000
T31 Burns classified according to extent of body surface involved	0.503	0.497	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.502	0.498	0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.502	0.498	0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.502	0.498	0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.502	0.498	0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.502	0.498	0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.502	0.498	0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.502	0.498	0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.502	0.498	0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.502	0.498	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.501	0.499	0.000
S10 Superficial injury of neck	0.499	0.500	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.499	0.501	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.498	0.502	0.000
G95.1 Vascular myelopathies	0.498	0.502	0.000
G62.2 Polyneuropathy due to other toxic agents	0.497	0.502	0.000
G62.1 Alcoholic polyneuropathy	0.497	0.502	0.000
G62.0 Drug-induced polyneuropathy	0.497	0.502	0.000
M54.29 Cervicalgia-Site unspe	0.496	0.504	0.000
M65.34 Trigger finger-Hand	0.496	0.504	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.496	0.504	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.496	0.504	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.496	0.504	0.000
T23.2 Burn of second degree of wrist and hand	0.495	0.505	0.000
S59 Other and unspecified injuries of forearm	0.494	0.506	0.000
S58 Traumatic amputation of forearm	0.494	0.506	0.000
S57 Crushing injury of forearm	0.494	0.506	0.000
S55 Injury of blood vessels at forearm level	0.494	0.506	0.000
S54 Injury of nerves at forearm level	0.494	0.506	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.494	0.506	0.000
G90.8 Other disorders of autonomic nervous system	0.493	0.507	0.000
G90.4 Autonomic dysreflexia	0.493	0.507	0.000
G90.3 Multisystem degeneration	0.493	0.507	0.000
G90.2 Horner's syndrome	0.493	0.507	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.493	0.507	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.493	0.507	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.493	0.507	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.492	0.508	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.492	0.508	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.492	0.508	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.492	0.508	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.492	0.508	0.000
G63.1 Polyneuropathy in neoplastic disease	0.492	0.508	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.492	0.508	0.000
T65 Toxic effect of other and unspecified substances	0.491	0.509	0.000
T62 Toxic effect of other noxious substances eaten as food	0.491	0.509	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.491	0.509	0.000
T60 Toxic effect of pesticides	0.491	0.509	0.000
T57 Toxic effect of other inorganic substances	0.491	0.509	0.000
T56 Toxic effect of metals	0.491	0.509	0.000
T54 Toxic effect of corrosive substances	0.491	0.509	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.491	0.509	0.000
T52 Toxic effect of organic solvents	0.491	0.509	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.491	0.509	0.000
T58 Toxic effect of carbon monoxide	0.491	0.509	0.000
T55 Toxic effect of soaps and detergents	0.491	0.509	0.000
S17 Crushing injury of neck	0.491	0.509	0.000
S15 Injury of blood vessels at neck level	0.491	0.509	0.000
S14 Injury of nerves and spinal cord at neck level	0.491	0.509	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.491	0.509	0.000
S11 Open wound of neck	0.491	0.509	0.000
S18 Traumatic amputation at neck level	0.491	0.509	0.000
S16 Injury of muscle and tendon at neck level	0.491	0.509	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.489	0.510	0.000
Q80-Q89 Other congenital malformations	0.489	0.511	0.000
G62.8 Other specified polyneuropathies	0.489	0.511	0.000
S50 Superficial injury of forearm	0.488	0.512	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.488	0.512	0.000
Chapter VIII Diseases of the ear and mastoid process	0.487	0.513	0.000
T98 Sequelae of other and unspecified effects of external causes	0.487	0.513	0.000
Q50-Q56 Congenital malformations of genital organs	0.485	0.515	0.000
G44.0 Cluster headache syndrome	0.485	0.515	0.000
G58 Other mononeuropathies	0.485	0.515	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.483	0.517	0.000
B35-B49 Mycoses	0.483	0.517	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.482	0.518	0.000
G23 Other degenerative diseases of basal ganglia	0.481	0.518	0.000
G21 Secondary Parkinsonism	0.481	0.518	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.481	0.518	0.000
G22 Parkinsonism in diseases classified elsewhere	0.481	0.518	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.481	0.519	0.000
M66.4 Spontaneous rupture of other tendons	0.481	0.519	0.000
M66.3 Spontaneous rupture of flexor tendons	0.481	0.519	0.000
M66.2 Spontaneous rupture of extensor tendons	0.481	0.519	0.000
M66.1 Rupture of synovium	0.481	0.519	0.000
T79-T79 Certain early complications of trauma	0.481	0.519	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.481	0.519	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.480	0.520	0.000
S30.0 Contusion of lower back and pelvis	0.480	0.520	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.480	0.520	0.000
G57.5 Tarsal tunnel syndrome	0.480	0.520	0.000
G57.4 Lesion of medial popliteal nerve	0.480	0.520	0.000
G57.3 Lesion of lateral popliteal nerve	0.480	0.520	0.000
G57.2 Lesion of femoral nerve	0.480	0.520	0.000
G57.1 Meralgia paraesthetica	0.480	0.520	0.000
G57.0 Lesion of sciatic nerve	0.480	0.520	0.000
T95 Sequelae of burns, corrosions and frostbite	0.480	0.520	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.480	0.520	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.480	0.520	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.480	0.520	0.000
S20-S29 Injuries to the thorax	0.478	0.521	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.478	0.522	0.000
Q35-Q37 Cleft lip and cleft palate	0.478	0.522	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.478	0.522	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.478	0.522	0.000
M54.8 Other dorsalgia	0.478	0.522	0.000
M54.6 Pain in thoracic spine	0.478	0.522	0.000
M54.0 Panniculitis affecting regions of neck and back	0.478	0.522	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.478	0.522	0.000
G46.7 Other lacunar syndromes	0.478	0.522	0.000
G46.6 Pure sensory lacunar syndrome	0.478	0.522	0.000
G46.5 Pure motor lacunar syndrome	0.478	0.522	0.000
G46.4 Cerebellar stroke syndrome	0.478	0.522	0.000
G46.3 Brain stem stroke syndrome	0.478	0.522	0.000
G46.2 Posterior cerebral artery syndrome	0.478	0.522	0.000
G46.1 Anterior cerebral artery syndrome	0.478	0.522	0.000
G46.0 Middle cerebral artery syndrome	0.478	0.522	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.477	0.523	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.477	0.523	0.000
G60.3 Idiopathic progressive neuropathy	0.477	0.523	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.477	0.523	0.000
G60.1 Refsum's disease	0.477	0.523	0.000
G12.9 Spinal muscular atrophy, unspecified	0.476	0.523	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.476	0.523	0.000
G12.1 Other inherited spinal muscular atrophy	0.476	0.523	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.476	0.523	0.000
M50.1 Cervical disk disorder with radiculopathy	0.476	0.524	0.000
M20-M25 Other joint disorders	0.475	0.525	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.475	0.525	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.475	0.525	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.475	0.525	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.475	0.525	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.475	0.525	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.475	0.525	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.475	0.525	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.475	0.525	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.475	0.525	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.475	0.525	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.475	0.525	0.000
G24 Dystonia	0.474	0.526	0.000
T23.3 Burn of third degree of wrist and hand	0.474	0.526	0.000
Q60-Q64 Congenital malformations of the urinary system	0.473	0.526	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.473	0.527	0.000
S37 Injury of urinary and pelvic organs	0.473	0.527	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations