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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12660817
log Bayes Factor = 9.11468
Chromosome 6   position 31,336,757  (GRCh37) Explore rs12660817 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.990 0.010 0.000
M20-M25 Other joint disorders
0.979 0.021 0.000
K90.0 Coeliac disease
0.000 0.031 0.969
M70-M79 Other soft tissue disorders
0.966 0.034 0.000
M35 Other systemic involvement of connective tissue
0.962 0.038 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.958 0.042 0.000
M35.3 Polymyalgia rheumatica
0.958 0.042 0.000
C44.3 Skin of other and unspecified parts of face
0.000 0.042 0.958
M79.6 Pain in limb
0.942 0.058 0.000
C44 Other malignant neoplasms of skin
0.000 0.061 0.939
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.936 0.064 0.000
C44.4 Skin of scalp and neck
0.000 0.075 0.925
M80-M85 Disorders of bone density and structure
0.919 0.081 0.000
M05 Seropositive rheumatoid arthritis
0.919 0.081 0.000
M65-M68 Disorders of synovium and tendon
0.910 0.090 0.000
M06.3 Rheumatoid nodule
0.910 0.090 0.000
M79.64 Pain in limb (Hand)
0.905 0.095 0.000
E10 Insulin-dependent diabetes mellitus
0.884 0.116 0.000
M79.7 Fibromyalgia
0.883 0.117 0.000
E10-E14 Diabetes mellitus
0.883 0.117 0.000
E10.9 Without complications
0.880 0.120 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.870 0.130 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.869 0.131 0.000
E11 Non-insulin-dependent diabetes mellitus
0.868 0.132 0.000
E14 Unspecified diabetes mellitus
0.863 0.137 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.863 0.137 0.000
E11.9 Without complications
0.862 0.138 0.000
E14.9 Without complications
0.853 0.147 0.000
M31 Other necrotising vasculopathies
0.852 0.148 0.000
M65 Synovitis and tenosynovitis
0.851 0.149 0.000
M79.66 Pain in limb (Lower leg)
0.849 0.151 0.000
M24 Other specific joint derangements
0.848 0.152 0.000
M12 Other specific arthropathies
0.832 0.168 0.000
M79.79 Fibromyalgia (Site unspecified)
0.829 0.171 0.000
M84 Disorders of continuity of bone
0.829 0.171 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.176 0.824
M79.1 Myalgia
0.819 0.181 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.815 0.185 0.000
M06.34 Rheumatoid nodule (Hand)
0.813 0.187 0.000
M60-M63 Disorders of muscles
0.811 0.189 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.793 0.207 0.000
C44.7 Skin of lower limb, including hip
0.000 0.216 0.784
M65.9 Synovitis and tenosynovitis, unspecified
0.781 0.219 0.000
M20 Acquired deformities of fingers and toes
0.779 0.221 0.000
M30 Polyarteritis nodosa and related conditions
0.776 0.224 0.000
M86-M90 Other osteopathies
0.767 0.233 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.766 0.234 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.763 0.237 0.000
M91-M94 Chondropathies
0.763 0.237 0.000
C44.5 Skin of trunk
0.000 0.238 0.762
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.757 0.243 0.000
E11.4 With neurological complications
0.753 0.247 0.000
M35.1 Other overlap syndromes
0.750 0.250 0.000
M21 Other acquired deformities of limbs
0.746 0.254 0.000
E11.5 With peripheral circulatory complications
0.746 0.254 0.000
M82 Osteoporosis in diseases classified elsewhere
0.742 0.258 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.742 0.258 0.000
E10.5 With peripheral circulatory complications
0.741 0.259 0.000
M31.6 Other giant cell arteritis
0.738 0.262 0.000
M79.63 Pain in limb (Forearm)
0.738 0.262 0.000
M79.15 Myalgia (Pelvic region and thigh)
0.737 0.263 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.736 0.264 0.000
M81 Osteoporosis without pathological fracture
0.736 0.264 0.000
M79.67 Pain in limb (Ankle and foot)
0.735 0.265 0.000
M00-M03 Infectious arthropathies
0.735 0.265 0.000
E10.1 With ketoacidosis
0.734 0.266 0.000
M66 Spontaneous rupture of synovium and tendon
0.732 0.268 0.000
M79.2 Neuralgia and neuritis, unspecified
0.731 0.269 0.000
M32 Systemic lupus erythematosus
0.725 0.275 0.000
M10 Gout
0.724 0.276 0.000
C44.0 Skin of lip
0.000 0.280 0.720
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.712 0.288 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.706 0.294 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.706 0.294 0.000
M84.0 Malunion of fracture
0.705 0.295 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.702 0.298 0.000
M33 Dermatopolymyositis
0.702 0.298 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.702 0.298 0.000
M34 Systemic sclerosis
0.699 0.301 0.000
E10.3 With ophthalmic complications
0.697 0.303 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.695 0.305 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.693 0.307 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.690 0.310 0.000
M35.8 Other specified systemic involvement of connective tissue
0.690 0.310 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.690 0.310 0.000
M35.5 Multifocal fibrosclerosis
0.690 0.310 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.690 0.310 0.000
M35.2 Behcet's disease
0.690 0.310 0.000
M20.5 Other deformities of toe(s) (acquired)
0.688 0.312 0.000
M06.4 Inflammatory polyarthropathy
0.688 0.312 0.000
M79.9 Soft tissue disorder, unspecified
0.687 0.313 0.000
M79.3 Panniculitis, unspecified
0.687 0.313 0.000
M79.62 Pain in limb (Upper arm)
0.686 0.314 0.000
M79.61 Pain in limb (Shoulder region)
0.685 0.315 0.000
E13 Other specified diabetes mellitus
0.683 0.317 0.000
M62 Other disorders of muscle
0.680 0.320 0.000
E10.6 With other specified complications
0.679 0.321 0.000
E11.8 With unspecified complications
0.675 0.325 0.000
M79.68 Pain in limb (Other)
0.675 0.325 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.674 0.326 0.000
C44.8 Overlapping lesion of skin
0.000 0.326 0.673
M12.2 Villonodular synovitis (pigmented)
0.673 0.327 0.000
M79.5 Residual foreign body in soft tissue
0.670 0.329 0.000
M89 Other disorders of bone
0.670 0.330 0.000
M24.1 Other articular cartilage disorders
0.669 0.331 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.668 0.332 0.000
M76 Enthesopathies of lower limb, excluding foot
0.667 0.333 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.667 0.333 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.334 0.666
E10.8 With unspecified complications
0.663 0.336 0.000
M40-M43 Deforming dorsopathies
0.662 0.337 0.000
M11 Other crystal arthropathies
0.659 0.341 0.000
M12.3 Palindromic rheumatism
0.659 0.341 0.000
M83 Adult osteomalacia
0.659 0.341 0.000
M05.8 Other seropositive rheumatoid arthritis
0.659 0.341 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.659 0.341 0.000
M05.2 Rheumatoid vasculitis
0.659 0.341 0.000
M05.1 Rheumatoid lung disease
0.659 0.341 0.000
M05.0 Felty's syndrome
0.659 0.341 0.000
M79.0 Rheumatism, unspecified
0.657 0.343 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.653 0.347 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.653 0.347 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.652 0.347 0.000
M06.38 Rheumatoid nodule (Other)
0.652 0.347 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.652 0.347 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.652 0.347 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.652 0.347 0.000
M06.33 Rheumatoid nodule (Forearm)
0.652 0.347 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.652 0.347 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.652 0.347 0.000
M24.0 Loose body in joint
0.652 0.348 0.000
M77 Other enthesopathies
0.651 0.348 0.000
M85 Other disorders of bone density and structure
0.648 0.352 0.000
M31.3 Wegener's granulomatosis
0.646 0.354 0.000
M79.69 Pain in limb (Site unspecified)
0.641 0.359 0.000
M65.8 Other synovitis and tenosynovitis
0.636 0.363 0.000
M71 Other bursopathies
0.636 0.364 0.000
M24.5 Contracture of joint
0.635 0.365 0.000
M24.2 Disorder of ligament
0.635 0.365 0.000
M20.1 Hallux valgus (acquired)
0.634 0.366 0.000
E10.7 With multiple complications
0.634 0.366 0.000
E10.2 With renal complications
0.634 0.366 0.000
E10.0 With coma
0.634 0.366 0.000
M79.78 Fibromyalgia (Other)
0.633 0.367 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.633 0.367 0.000
M79.76 Fibromyalgia (Lower leg)
0.633 0.367 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.633 0.367 0.000
M79.74 Fibromyalgia (Hand)
0.633 0.367 0.000
M79.73 Fibromyalgia (Forearm)
0.633 0.367 0.000
M79.72 Fibromyalgia (Upper arm)
0.633 0.367 0.000
M79.71 Fibromyalgia (Shoulder region)
0.633 0.367 0.000
M79.70 Fibromyalgia (Multiple sites)
0.633 0.367 0.000
E12 Malnutrition-related diabetes mellitus
0.633 0.367 0.000
M35.7 Hypermobility syndrome
0.631 0.369 0.000
E11.0 With coma
0.631 0.369 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.630 0.369 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.628 0.372 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.626 0.374 0.000
M79.16 Myalgia (Lower leg)
0.625 0.375 0.000
E11.7 With multiple complications
0.623 0.377 0.000
M20.4 Other hammer toe(s) (acquired)
0.623 0.377 0.000
E14.8 With unspecified complications
0.619 0.381 0.000
E14.7 With multiple complications
0.619 0.381 0.000
E14.6 With other specified complications
0.619 0.381 0.000
E14.5 With peripheral circulatory complications
0.619 0.381 0.000
E14.4 With neurological complications
0.619 0.381 0.000
E14.2 Withrenal complications
0.619 0.381 0.000
E14.1 With ketoacidosis
0.619 0.381 0.000
E14.0 With coma
0.619 0.381 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.619 0.381 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.619 0.381 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.619 0.381 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.619 0.381 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.619 0.381 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.619 0.381 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.619 0.381 0.000
M75 Shoulder lesions
0.618 0.382 0.000
M82.1 Osteoporosis in endocrine disorders
0.616 0.384 0.000
M92 Other juvenile osteochondrosis
0.615 0.384 0.000
M80 Osteoporosis with pathological fracture
0.611 0.389 0.000
M31.9 Necrotising vasculopathy, unspecified
0.611 0.389 0.000
M31.8 Other specified necrotising vasculopathies
0.611 0.389 0.000
M31.7 Microscopic polyangiitis
0.611 0.389 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.611 0.389 0.000
M31.2 Lethal midline granuloma
0.611 0.389 0.000
M31.1 Thrombotic microangiopathy
0.611 0.389 0.000
M31.0 Hypersensitivity angiitis
0.611 0.389 0.000
M65.2 Calcific tendinitis
0.610 0.389 0.000
M65.1 Other infective (teno)synovitis
0.610 0.389 0.000
M65.0 Abscess of tendon sheath
0.610 0.389 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.609 0.391 0.000
M24.9 Joint derangement, unspecified
0.608 0.392 0.000
M24.7 Protrusio acetabuli
0.608 0.392 0.000
M24.6 Ankylosis of joint
0.608 0.392 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.608 0.392 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.607 0.393 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.603 0.397 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.601 0.399 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.597 0.403 0.000
M12.5 Traumatic arthropathy
0.597 0.403 0.000
M12.4 Intermittent hydrarthrosis
0.597 0.403 0.000
M12.1 Kaschin-Beck disease
0.597 0.403 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.597 0.403 0.000
M66.2 Spontaneous rupture of extensor tendons
0.596 0.404 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.596 0.404 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.596 0.404 0.000
M84.4 Pathological fracture, not elsewhere classified
0.595 0.405 0.000
M84.9 Disorder of continuity of bone, unspecified
0.594 0.406 0.000
M84.8 Other disorders of continuity of bone
0.594 0.406 0.000
M84.3 Stress fracture, not elsewhere classified
0.594 0.406 0.000
M84.2 Delayed union of fracture
0.594 0.406 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.594 0.406 0.000
M89.0 Algoneurodystrophy
0.594 0.406 0.000
M72 Fibroblastic disorders
0.592 0.407 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.593 0.407 0.000
M84.04 Malunion of fracture (Hand)
0.592 0.408 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.589 0.411 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.588 0.412 0.000
M79.19 Myalgia (Site unspecified)
0.587 0.413 0.000
M79.17 Myalgia (Ankle and foot)
0.587 0.413 0.000
M79.14 Myalgia (Hand)
0.587 0.413 0.000
M79.13 Myalgia (Forearm)
0.587 0.413 0.000
M79.12 Myalgia (Upper arm)
0.587 0.413 0.000
M79.11 Myalgia (Shoulder region)
0.587 0.413 0.000
M21.2 Flexion deformity
0.586 0.413 0.000
M62.8 Other specified disorders of muscle
0.586 0.414 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.582 0.418 0.000
M86 Osteomyelitis
0.581 0.418 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.581 0.419 0.000
M61 Calcification and ossification of muscle
0.581 0.419 0.000
M60 Myositis
0.581 0.419 0.000
M81.4 Drug-induced osteoporosis
0.577 0.423 0.000
M21.3 Wrist or foot drop (acquired)
0.575 0.424 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.426 0.574
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.567 0.433 0.000
M06.0 Seronegative rheumatoid arthritis
0.567 0.433 0.000
M25 Other joint disorders, not elsewhere classified
0.565 0.435 0.000
M81.9 Osteoporosis, unspecified
0.564 0.436 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.560 0.440 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.560 0.440 0.000
M12.24 Villonodular synovitis (pigmented) (Hand)
0.559 0.441 0.000
M21.0 Valgus deformity, not elsewhere classified
0.557 0.442 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.556 0.444 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.556 0.444 0.000
M30.2 Juvenile polyarteritis
0.556 0.444 0.000
M30.0 Polyarteritis nodosa
0.556 0.444 0.000
M20.0 Deformity of finger(s)
0.556 0.444 0.000
M79.18 Myalgia (Other)
0.551 0.449 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.550 0.450 0.000
M00 Pyogenic arthritis
0.549 0.451 0.000
M84.03 Malunion of fracture (Forearm)
0.549 0.451 0.000
M93 Other osteochondropathies
0.548 0.452 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.547 0.453 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.545 0.455 0.000
E11.2 With renal complications
0.544 0.456 0.000
M70.2 Olecranon bursitis
0.544 0.456 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.543 0.457 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.543 0.457 0.000
E14.3 With ophthalmic complications
0.543 0.457 0.000
E10.4 With neurological complications
0.542 0.457 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.540 0.460 0.000
E13.9 Without complications
0.540 0.460 0.000
M66.0 Rupture of popliteal cyst
0.537 0.463 0.000
M70.4 Prepatellar bursitis
0.537 0.463 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.535 0.464 0.000
M21.9 Acquired deformity of limb, unspecified
0.535 0.465 0.000
M21.8 Other specified acquired deformities of limbs
0.535 0.465 0.000
M21.7 Unequal limb length (acquired)
0.535 0.465 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.535 0.465 0.000
M67 Other disorders of synovium and tendon
0.534 0.466 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.532 0.468 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.532 0.468 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.532 0.468 0.000
M79.60 Pain in limb (Multiple sites)
0.530 0.469 0.000
M07 Psoriatic and enteropathic arthropathies
0.529 0.470 0.001
M10.9 Gout, unspecified
0.528 0.472 0.000
M21.4 Flat foot [pes planus] (acquired)
0.528 0.472 0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.528 0.472 0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.528 0.472 0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.528 0.472 0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.528 0.472 0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.528 0.472 0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.528 0.472 0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.528 0.472 0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.528 0.472 0.000
M81.8 Other osteoporosis
0.528 0.472 0.000
M81.6 Localised osteoporosis [Lequesne]
0.528 0.472 0.000
M81.5 Idiopathic osteoporosis
0.528 0.472 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.528 0.472 0.000
M81.2 Osteoporosis of disuse
0.528 0.472 0.000
M81.1 Postoophorectomy osteoporosis
0.528 0.472 0.000
M81.0 Postmenopausal osteoporosis
0.528 0.472 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.527 0.473 0.000
M02 Reactive arthropathies
0.527 0.473 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.527 0.473 0.000
M79.10 Myalgia (Multiple sites)
0.525 0.475 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.525 0.475 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.525 0.475 0.000
M66.4 Spontaneous rupture of other tendons
0.525 0.475 0.000
M66.3 Spontaneous rupture of flexor tendons
0.525 0.475 0.000
M66.1 Rupture of synovium
0.525 0.475 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.524 0.476 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.524 0.476 0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)
0.524 0.476 0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)
0.524 0.476 0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)
0.524 0.476 0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)
0.524 0.476 0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)
0.524 0.476 0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)
0.524 0.476 0.000
M34.8 Other forms of systemic sclerosis
0.523 0.476 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.522 0.478 0.000
M24.01 Loose body in joint (Shoulder region)
0.522 0.478 0.000
M22 Disorders of patella
0.520 0.479 0.000
M94 Other disorders of cartilage
0.520 0.480 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.520 0.480 0.000
M32.8 Other forms of systemic lupus erythematosus
0.520 0.480 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.520 0.480 0.000
M10.4 Other secondary gout
0.519 0.481 0.000
M10.3 Gout due to impairment of renal function
0.519 0.481 0.000
M10.2 Drug-induced gout
0.519 0.481 0.000
M10.1 Lead-induced gout
0.519 0.481 0.000
M10.0 Idiopathic gout
0.519 0.481 0.000
M75.5 Bursitis of shoulder
0.519 0.481 0.000
M88 Paget's disease of bone [osteitis deformans]
0.518 0.482 0.000
M65.3 Trigger finger
0.515 0.484 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.515 0.485 0.000
M92.7 Juvenile osteochondrosis of metatarsus
0.513 0.487 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.513 0.487 0.000
M06.18 Adult-onset Still's disease (Other)
0.513 0.487 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.513 0.487 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.513 0.487 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.513 0.487 0.000
M06.14 Adult-onset Still's disease (Hand)
0.513 0.487 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.513 0.487 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.513 0.487 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.513 0.487 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.513 0.487 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.513 0.487 0.000
M06.28 Rheumatoid bursitis (Other)
0.513 0.487 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.513 0.487 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.513 0.487 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.513 0.487 0.000
M06.24 Rheumatoid bursitis (Hand)
0.513 0.487 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.513 0.487 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.513 0.487 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.513 0.487 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.513 0.487 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.513 0.487 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.513 0.487 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.513 0.487 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.513 0.487 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.513 0.487 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.513 0.487 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.513 0.487 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.513 0.487 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.513 0.487 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.513 0.487 0.000
M08.9 Juvenile arthritis, unspecified
0.512 0.488 0.000
M08.8 Other juvenile arthritis
0.512 0.488 0.000
M08.4 Pauciarticular juvenile arthritis
0.512 0.488 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.512 0.488 0.000
M08.2 Juvenile arthritis with systemic onset
0.512 0.488 0.000
M08.1 Juvenile ankylosing spondylitis
0.512 0.488 0.000
M08.0 Juvenile rheumatoid arthritis
0.512 0.488 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.512 0.488 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.512 0.488 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.512 0.488 0.000
M09.0 Juvenile arthritis in psoriasis
0.512 0.488 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.509 0.490 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.508 0.491 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.508 0.491 0.000
M70.7 Other bursitis of hip
0.508 0.491 0.000
M70.5 Other bursitis of knee
0.508 0.491 0.000
M70.3 Other bursitis of elbow
0.508 0.491 0.000
M70.1 Bursitis of hand
0.508 0.491 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.508 0.491 0.000
M75.4 Impingement syndrome of shoulder
0.508 0.492 0.000
M34.1 CR(E)ST syndrome
0.507 0.492 0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)
0.506 0.493 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.506 0.493 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.506 0.493 0.000
M14.4 Arthropathy in amyloidosis
0.506 0.493 0.000
M14.3 Lipoid dermatoarthritis
0.506 0.493 0.000
M14.2 Diabetic arthropathy
0.506 0.493 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.506 0.493 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.506 0.493 0.000
M41 Scoliosis
0.506 0.494 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.506 0.494 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.506 0.494 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.506 0.494 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.506 0.494 0.000
M84.09 Malunion of fracture (Site unspecified)
0.506 0.494 0.000
M84.08 Malunion of fracture (Other)
0.506 0.494 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.506 0.494 0.000
M84.06 Malunion of fracture (Lower leg)
0.506 0.494 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.506 0.494 0.000
M84.02 Malunion of fracture (Upper arm)
0.506 0.494 0.000
M84.01 Malunion of fracture (Shoulder region)
0.506 0.494 0.000
M84.00 Malunion of fracture (Multiple sites)
0.506 0.494 0.000
M33.9 Dermatopolymyositis, unspecified
0.503 0.497 0.000
M33.2 Polymyositis
0.503 0.497 0.000
M33.1 Other dermatomyositis
0.503 0.497 0.000
M33.0 Juvenile dermatomyositis
0.503 0.497 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.503 0.497 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.503 0.497 0.000
M36.3 Arthropathy in other blood disorders
0.503 0.497 0.000
M36.2 Haemophilic arthropathy
0.503 0.497 0.000
M36.1 Arthropathy in neoplastic disease
0.503 0.497 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.503 0.497 0.000
M89.8 Other specified disorders of bone
0.502 0.498 0.000
M21.6 Other acquired deformities of ankle and foot
0.502 0.498 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.501 0.499 0.000
M34.0 Progressive systemic sclerosis
0.501 0.499 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.500 0.500 0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)
0.499 0.501 0.000
M90 Osteopathies in diseases classified elsewhere
0.499 0.501 0.000
M14.6 Neuropathic arthropathy
0.499 0.501 0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec
0.498 0.501 0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)
0.498 0.501 0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)
0.498 0.501 0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)
0.498 0.501 0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)
0.498 0.501 0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)
0.498 0.501 0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)
0.498 0.501 0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)
0.498 0.501 0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)
0.498 0.501 0.000
M24.26 Disorder of ligament (Lower leg)
0.498 0.502 0.000
M73.8 Other soft tissue disorders in diseases classified elsewhere
0.497 0.503 0.000
M73.1 Syphilitic bursitis
0.497 0.503 0.000
M73.0 Gonococcal bursitis
0.497 0.503 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.495 0.505 0.000
M77.4 Metatarsalgia
0.494 0.506 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.493 0.507 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.493 0.507 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.493 0.507 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.493 0.507 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.493 0.507 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.493 0.507 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.493 0.507 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.493 0.507 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.493 0.507 0.000
M89.5 Osteolysis
0.493 0.507 0.000
E11.6 With other specified complications
0.493 0.507 0.000
M79.39 Panniculitis, unspecified (Site unspecified)
0.493 0.507 0.000
M79.38 Panniculitis, unspecified (Other)
0.493 0.507 0.000
M79.37 Panniculitis, unspecified (Ankle and foot)
0.493 0.507 0.000
M79.36 Panniculitis, unspecified (Lower leg)
0.493 0.507 0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)
0.493 0.507 0.000
M79.34 Panniculitis, unspecified (Hand)
0.493 0.507 0.000
M79.33 Panniculitis, unspecified (Forearm)
0.493 0.507 0.000
M79.32 Panniculitis, unspecified (Upper arm)
0.493 0.507 0.000
M79.31 Panniculitis, unspecified (Shoulder region)
0.493 0.507 0.000
M79.30 Panniculitis, unspecified (Multiple sites)
0.493 0.507 0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)
0.493 0.507 0.000
M79.98 Soft tissue disorder, unspecified (Other)
0.493 0.507 0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)
0.493 0.507 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.493 0.507 0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)
0.493 0.507 0.000
M79.94 Soft tissue disorder, unspecified (Hand)
0.493 0.507 0.000
M79.93 Soft tissue disorder, unspecified (Forearm)
0.493 0.507 0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)
0.493 0.507 0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)
0.493 0.507 0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)
0.493 0.507 0.000
C44.1 Skin of eyelid, including canthus
0.000 0.507 0.493
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.493 0.507 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.491 0.509 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.490 0.510 0.000
E13.8 With unspecified complications
0.490 0.510 0.000
E13.7 With multiple complications
0.490 0.510 0.000
E13.6 With other specified complications
0.490 0.510 0.000
E13.5 With peripheral circulatory complications
0.490 0.510 0.000
E13.4 With neurological complications
0.490 0.510 0.000
E13.3 With ophthalmic complications
0.490 0.510 0.000
E13.2 With renal complications
0.490 0.510 0.000
E13.1 With ketoacidosis
0.490 0.510 0.000
E13.0 With coma
0.490 0.510 0.000
M20.3 Other deformity of hallux (acquired)
0.488 0.512 0.000
M62.9 Disorder of muscle, unspecified
0.487 0.513 0.000
M62.6 Muscle strain
0.487 0.513 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.487 0.513 0.000
M62.4 Contracture of muscle
0.487 0.513 0.000
M62.3 Immobility syndrome (paraplegic)
0.487 0.513 0.000
M62.2 Ischaemic infarction of muscle
0.487 0.513 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.487 0.513 0.000
M62.0 Diastasis of muscle
0.487 0.513 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.487 0.513 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.482 0.517 0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)
0.482 0.517 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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