TreeWAS – Variant ID: rs12666280

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F20.9 Schizophrenia, unspecified	0.089	0.911	0.000
F20 Schizophrenia	0.081	0.919	0.000
F20.0 Paranoid schizophrenia	0.079	0.921	0.000
F20.8 Other schizophrenia	0.064	0.936	0.000
F20.2 Catatonic schizophrenia	0.059	0.940	0.000
F20.6 Simple schizophrenia	0.058	0.942	0.000
F20.4 Postschizophrenic depression	0.058	0.942	0.000
F20.3 Undifferentiated schizophrenia	0.058	0.942	0.000
F20.1 Hebephrenic schizophrenia	0.058	0.942	0.000
F20.5 Residual schizophrenia	0.056	0.944	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.949	0.051
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.030	0.970	0.000
R73 Elevated blood glucose level	0.000	0.971	0.029
F22 Persistent delusional disorders	0.024	0.976	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.976	0.024
F21 Schizotypal disorder	0.022	0.978	0.000
Q21.1 Atrial septal defect	0.022	0.978	0.000
F28 Other nonorganic psychotic disorders	0.021	0.979	0.000
F24 Induced delusional disorder	0.021	0.979	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.979	0.021
F22.0 Delusional disorder	0.021	0.979	0.000
F29 Unspecified nonorganic psychosis	0.020	0.980	0.000
F23 Acute and transient psychotic disorders	0.019	0.981	0.000
F25 Schizoaffective disorders	0.018	0.982	0.000
Q21 Congenital malformations of cardiac septa	0.018	0.982	0.000
F22.8 Other persistent delusional disorders	0.017	0.982	0.000
F22.9 Persistent delusional disorder, unspecified	0.017	0.983	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.017	0.983	0.000
Q28 Other congenital malformations of circulatory system	0.016	0.984	0.000
F25.1 Schizoaffective disorder, depressive type	0.015	0.984	0.000
S00.0 Superficial injury of scalp	0.015	0.985	0.000
F23.8 Other acute and transient psychotic disorders	0.015	0.985	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.015	0.985	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.014	0.986	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.014	0.986	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.014	0.986	0.000
Q21.0 Ventricular septal defect	0.014	0.986	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.013	0.986	0.000
F25.8 Other schizoaffective disorders	0.013	0.987	0.000
F25.2 Schizoaffective disorder, mixed type	0.013	0.987	0.000
Q21.4 Aortopulmonary septal defect	0.013	0.987	0.000
Q21.2 Atrioventricular septal defect	0.013	0.987	0.000
Q25 Congenital malformations of great arteries	0.013	0.987	0.000
Q21.8 Other congenital malformations of cardiac septa	0.013	0.987	0.000
Q21.3 Tetralogy of Fallot	0.012	0.987	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.012	0.988	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.012	0.988	0.000
Q28.3 Other malformations of cerebral vessels	0.012	0.988	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.011	0.988	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.011	0.988	0.000
Q28.1 Other malformations of precerebral vessels	0.011	0.988	0.000
Q26 Congenital malformations of great veins	0.011	0.988	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.011	0.989	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.011	0.989	0.000
F25.0 Schizoaffective disorder, manic type	0.011	0.989	0.000
Z90.5 Acquired absence of kidney	0.000	0.989	0.011
M79.60 Pain in limb (Multiple sites)	0.010	0.990	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.010	0.990	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.010	0.990	0.000
Q25.3 Stenosis of aorta	0.010	0.990	0.000
Q23 Congenital malformations of aortic and mitral valves	0.010	0.990	0.000
F25.9 Schizoaffective disorder, unspecified	0.010	0.990	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.010	0.990	0.000
Q25.6 Stenosis of pulmonary artery	0.010	0.990	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.990	0.010
Q24 Other congenital malformations of heart	0.010	0.990	0.000
Q25.1 Coarctation of aorta	0.009	0.990	0.000
Q25.0 Patent ductus arteriosus	0.009	0.990	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.009	0.991	0.000
Q25.8 Other congenital malformations of great arteries	0.009	0.991	0.000
Q25.5 Atresia of pulmonary artery	0.009	0.991	0.000
Q25.2 Atresia of aorta	0.009	0.991	0.000
Q25.4 Other congenital malformations of aorta	0.009	0.991	0.000
S06.8 Other intracranial injuries	0.009	0.991	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.009	0.991	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.009	0.991	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.008	0.991	0.000
Q26.8 Other congenital malformations of great veins	0.008	0.991	0.000
Q26.6 Portal vein-hepatic artery fistula	0.008	0.991	0.000
Q26.5 Anomalous portal venous connexion	0.008	0.991	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.008	0.991	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.008	0.991	0.000
Q26.1 Persistent left superior vena cava	0.008	0.991	0.000
Q26.0 Congenital stenosis of vena cava	0.008	0.991	0.000
S06 Intracranial injury	0.008	0.992	0.000
S06.2 Diffuse brain injury	0.008	0.992	0.000
S00 Superficial injury of head	0.008	0.992	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.008	0.992	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.008	0.992	0.000
Q20.6 Isomerism of atrial appendages	0.008	0.992	0.000
Q20.5 Discordant atrioventricular connexion	0.008	0.992	0.000
Q20.4 Double inlet ventricle	0.008	0.992	0.000
Q20.3 Discordant ventriculoarterial connexion	0.008	0.992	0.000
Q20.2 Double outlet left ventricle	0.008	0.992	0.000
Q20.1 Double outlet right ventricle	0.008	0.992	0.000
Q20.0 Common arterial trunk	0.008	0.992	0.000
S00.5 Superficial injury of lip and oral cavity	0.008	0.992	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.992	0.008
S06.6 Traumatic subarachnoid haemorrhage	0.008	0.992	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.007	0.992	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.007	0.992	0.000
Q23.4 Hypoplastic left heart syndrome	0.007	0.992	0.000
Q23.3 Congenital mitral insufficiency	0.007	0.992	0.000
Q23.2 Congenital mitral stenosis	0.007	0.992	0.000
Q23.0 Congenital stenosis of aortic valve	0.007	0.992	0.000
Q27 Other congenital malformations of peripheral vascular system	0.007	0.992	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.008	0.992	0.000
Q24.0 Dextrocardia	0.007	0.992	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.007	0.993	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.007	0.993	0.000
Q22.6 Hypoplastic right heart syndrome	0.007	0.993	0.000
Q22.4 Congenital tricuspid stenosis	0.007	0.993	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.007	0.993	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.007	0.993	0.000
Q22.0 Pulmonary valve atresia	0.007	0.993	0.000
Q24.5 Malformation of coronary vessels	0.007	0.993	0.000
Q24.6 Congenital heart block	0.007	0.993	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.007	0.993	0.000
Q24.4 Congenital subaortic stenosis	0.007	0.993	0.000
Q24.3 Pulmonary infundibular stenosis	0.007	0.993	0.000
Q24.2 Cor triatriatum	0.007	0.993	0.000
Q24.1 Levocardia	0.007	0.993	0.000
S72.30 Fracture of shaft of femur (closed)	0.007	0.993	0.000
S06.5 Traumatic subdural haemorrhage	0.007	0.993	0.000
S00.1 Contusion of eyelid and periocular area	0.007	0.993	0.000
Q22.5 Ebstein's anomaly	0.007	0.993	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.007	0.993	0.000
Q22.1 Congenital pulmonary valve stenosis	0.007	0.993	0.000
S00.3 Superficial injury of nose	0.007	0.993	0.000
Q23.1 Congenital insufficiency of aortic valve	0.007	0.993	0.000
Q24.8 Other specified congenital malformations of heart	0.006	0.993	0.000
Q54 Hypospadias	0.006	0.993	0.000
Q54.9 Hypospadias, unspecified	0.006	0.994	0.000
S00-S09 Injuries to the head	0.006	0.994	0.000
S06.7 Intracranial injury with prolonged coma	0.006	0.994	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.006	0.994	0.000
S00.4 Superficial injury of ear	0.006	0.994	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.006	0.994	0.000
Q52 Other congenital malformations of female genitalia	0.006	0.994	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.006	0.994	0.000
S06.1 Traumatic cerebral oedema	0.006	0.994	0.000
Q50-Q56 Congenital malformations of genital organs	0.006	0.994	0.000
S06.0 Concussion	0.006	0.994	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.006	0.994	0.000
Q27.4 Congenital phlebectasia	0.005	0.994	0.000
Q27.2 Other congenital malformations of renal artery	0.005	0.994	0.000
Q27.1 Congenital renal artery stenosis	0.005	0.994	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.005	0.994	0.000
Q54.0 Hypospadias, balanic	0.006	0.994	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.994	0.000
S06.4 Epidural haemorrhage	0.005	0.994	0.000
Q54.1 Hypospadias, penile	0.006	0.994	0.000
S01.0 Open wound of scalp	0.006	0.994	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.005	0.994	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.005	0.995	0.000
K01.1 Impacted teeth	0.005	0.995	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.005	0.995	0.000
Q52.1 Doubling of vagina	0.005	0.995	0.000
S06.9 Intracranial injury, unspecified	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
S06.3 Focal brain injury	0.005	0.995	0.000
S01 Open wound of head	0.005	0.995	0.000
Q52.5 Fusion of labia	0.005	0.995	0.000
Q76 Congenital malformations of spine and bony thorax	0.005	0.995	0.000
S08 Traumatic amputation of part of head	0.005	0.995	0.000
Q76.0 Spina bifida occulta	0.005	0.995	0.000
S03.2 Dislocation of tooth	0.005	0.995	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.995	0.005
Q52.4 Other congenital malformations of vagina	0.005	0.995	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.005	0.995	0.000
Q54.4 Congenital chordee	0.005	0.995	0.000
Q54.3 Hypospadias, perineal	0.005	0.995	0.000
Q54.2 Hypospadias, penoscrotal	0.005	0.995	0.000
Q27.3 Peripheral arteriovenous malformation	0.005	0.995	0.000
S07 Crushing injury of head	0.005	0.995	0.000
S04 Injury of cranial nerves	0.005	0.995	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.005	0.995	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.005	0.995	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.005	0.995	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.995	0.000
Q76.1 Klippel-Feil syndrome	0.005	0.995	0.000
O66 Other obstructed labour	0.000	0.995	0.005
F06.7 Mild cognitive disorder	0.005	0.995	0.000
S01.4 Open wound of cheek and temporomandibular area	0.005	0.995	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.995	0.005
Q54.8 Other hypospadias	0.004	0.995	0.000
S02 Fracture of skull and facial bones	0.005	0.995	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.004	0.995	0.000
Q52.7 Other congenital malformations of vulva	0.004	0.995	0.000
Q52.6 Congenital malformation of clitoris	0.004	0.995	0.000
Q52.3 Imperforate hymen	0.004	0.995	0.000
Q52.2 Congenital rectovaginal fistula	0.004	0.995	0.000
Q52.0 Congenital absence of vagina	0.004	0.995	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.004	0.995	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.995	0.005
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.995	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.995	0.004
S06.01 Concussion (with open intracranial wound)	0.004	0.996	0.000
S01.2 Open wound of nose	0.004	0.996	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.004	0.996	0.000
Q53 Undescended testicle	0.004	0.996	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.004	0.996	0.000
S03.4 Sprain and strain of jaw	0.004	0.996	0.000
S03.3 Dislocation of other and unspecified parts of head	0.004	0.996	0.000
S03.1 Dislocation of septal cartilage of nose	0.004	0.996	0.000
S02.8 Fractures of other skull and facial bones	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q76.5 Cervical rib	0.004	0.996	0.000
H11.3 Conjunctival haemorrhage	0.000	0.996	0.004
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.996	0.004
S08.1 Traumatic amputation of ear	0.004	0.996	0.000
S01.7 Multiple open wounds of head	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.004	0.996	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.004	0.996	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.004	0.996	0.000
S02.6 Fracture of mandible	0.004	0.996	0.000
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.996	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.004	0.996	0.000
S02.7 Multiple fractures involving skull and facial bones	0.004	0.996	0.000
S03.0 Dislocation of jaw	0.004	0.996	0.000
Q51.2 Other doubling of uterus	0.004	0.996	0.000
S08.9 Traumatic amputation of unspecified part of head	0.004	0.996	0.000
S08.8 Traumatic amputation of other parts of head	0.004	0.996	0.000
S08.0 Avulsion of scalp	0.004	0.996	0.000
S01.1 Open wound of eyelid and periocular area	0.004	0.996	0.000
S06.00 Concussion (without open intracranial wound)	0.004	0.996	0.000
N99.0 Postprocedural renal failure	0.000	0.996	0.004
R35 Polyuria	0.004	0.996	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.996	0.004
S01.5 Open wound of lip and oral cavity	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
S04.9 Injury of unspecified cranial nerve	0.004	0.996	0.000
S04.8 Injury of other cranial nerves	0.004	0.996	0.000
S04.7 Injury of accessory nerve	0.004	0.996	0.000
S04.6 Injury of acoustic nerve	0.004	0.996	0.000
S04.5 Injury of facial nerve	0.004	0.996	0.000
S04.4 Injury of abducent nerve	0.004	0.996	0.000
S04.3 Injury of trigeminal nerve	0.004	0.996	0.000
S04.2 Injury of trochlear nerve	0.004	0.996	0.000
S04.1 Injury of oculomotor nerve	0.004	0.996	0.000
S04.0 Injury of optic nerve and pathways	0.004	0.996	0.000
S07.9 Crushing injury of head, part unspecified	0.004	0.996	0.000
S07.8 Crushing injury of other parts of head	0.004	0.996	0.000
S07.1 Crushing injury of skull	0.004	0.996	0.000
S07.0 Crushing injury of face	0.004	0.996	0.000
Q53.2 Undescended testicle, bilateral	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.996	0.000
H11 Other disorders of conjunctiva	0.000	0.996	0.004
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.996	0.004
O66.1 Obstructed labour due to locked twins	0.000	0.996	0.004
Q38.6 Other congenital malformations of mouth	0.004	0.996	0.000
S02.60 Fracture of mandible (closed)	0.004	0.996	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
S02.5 Fracture of tooth	0.004	0.996	0.000
O66.9 Obstructed labour, unspecified	0.000	0.996	0.003
H54.7 Unspecified visual loss	0.000	0.996	0.004
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.003	0.996	0.000
C17.0 Duodenum	0.004	0.996	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.003	0.996	0.000
Q51.4 Unicornate uterus	0.003	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.996	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.996	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.996	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.996	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.996	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.996	0.000
O66.8 Other specified obstructed labour	0.000	0.997	0.003
Q31 Congenital malformations of larynx	0.003	0.997	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.997	0.003
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
S01.9 Open wound of head, part unspecified	0.003	0.997	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.997	0.003
Q53.0 Ectopic testis	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
O66.2 Obstructed labour due to unusually large foetus	0.000	0.997	0.003
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
S02.81 Fractures of other skull and facial bones (open)	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
C17.9 Small intestine, unspecified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.003	0.997	0.000
C17 Malignant neoplasm of small intestine	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.997	0.000
K11.5 Sialolithiasis	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
S72.3 Fracture of shaft of femur	0.003	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
S02.61 Fracture of mandible (open)	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
C17.2 Ileum	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.003	0.997	0.000
C32.0 Glottis	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q67.8 Other congenital deformities of chest	0.003	0.997	0.000
Q67.7 Pectus carinatum	0.003	0.997	0.000
Q67.3 Plagiocephaly	0.003	0.997	0.000
Q67.2 Dolichocephaly	0.003	0.997	0.000
Q67.1 Compression facies	0.003	0.997	0.000
Q67.0 Facial asymmetry	0.003	0.997	0.000
S00.7 Multiple superficial injuries of head	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
S01.3 Open wound of ear	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
S02.50 Fracture of tooth (closed)	0.003	0.997	0.000
N99.1 Postprocedural urethral stricture	0.000	0.997	0.003
Q31.3 Laryngocele	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.003	0.997	0.000
Q44.2 Atresia of bile ducts	0.003	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.003	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
S02.51 Fracture of tooth (open)	0.003	0.997	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
C17.1 Jejunum	0.003	0.997	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.997	0.003
R78.0 Finding of alcohol in blood	0.000	0.997	0.003
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
H11.2 Conjunctival scars	0.000	0.997	0.003
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.000	0.997	0.003
S02.4 Fracture of malar and maxillary bones	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.003	0.997	0.000
S00.8 Superficial injury of other parts of head	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.000	0.997	0.003
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.997	0.000
R52.1 Chronic intractable pain	0.000	0.997	0.003
Q31.0 Web of larynx	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.002	0.997	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.003	0.997	0.000
Q31.8 Other congenital malformations of larynx	0.003	0.997	0.000
Q31.5 Congenital laryngomalacia	0.003	0.997	0.000
Q31.4 Congenital laryngeal stridor	0.003	0.997	0.000
Q31.2 Laryngeal hypoplasia	0.003	0.997	0.000
Q31.1 Congenital subglottic stenosis	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.000	0.997	0.003
C15.4 Middle third of oesophagus	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.997	0.000
Q53.1 Undescended testicle, unilateral	0.002	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
Q99.8 Other specified chromosome abnormalities	0.003	0.997	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.997	0.000
C15.5 Lower third of oesophagus	0.003	0.997	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.997	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.997	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.997	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.997	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.997	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.997	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.997	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.997	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.997	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.997	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.997	0.000
Q69.9 Polydactyly, unspecified	0.002	0.997	0.000
Q69.2 Accessory toe(s)	0.002	0.997	0.000
Q69.1 Accessory thumb(s)	0.002	0.997	0.000
Q69.0 Accessory finger(s)	0.002	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.997	0.000
Q71.6 Lobster-claw hand	0.002	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.997	0.000
Q72.7 Split foot	0.002	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.997	0.000
Q77.5 Diastrophic dysplasia	0.002	0.997	0.000
Q77.4 Achondroplasia	0.002	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.997	0.000
Q77.2 Short rib syndrome	0.002	0.997	0.000
Q77.1 Thanatophoric short stature	0.002	0.997	0.000
Q77.0 Achondrogenesis	0.002	0.997	0.000
S02.01 Fracture of vault of skull (open)	0.003	0.997	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q17.5 Prominent ear	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.002	0.997	0.000
Q70.4 Polysyndactyly	0.002	0.997	0.000
Q70.2 Fused toes	0.002	0.997	0.000
Q70.1 Webbed fingers	0.002	0.997	0.000
Q70.0 Fused fingers	0.002	0.997	0.000
H11.8 Other specified disorders of conjunctiva	0.000	0.997	0.003
Q40.1 Congenital hiatus hernia	0.002	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.002	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.002	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.002	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.002	0.997	0.000
Q98.5 Karyotype 47,XYY	0.002	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.002	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations