TreeWAS – Variant ID: rs12875271

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.001	0.999
I25.2 Old myocardial infarction	0.000	0.010	0.990
I20-I25 Ischaemic heart diseases	0.000	0.024	0.976
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.027	0.973
I21 Acute myocardial infarction	0.000	0.048	0.952
I20 Angina pectoris	0.000	0.063	0.937
I20.9 Angina pectoris, unspecified	0.000	0.079	0.921
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.121	0.879
I25.5 Ischaemic cardiomyopathy	0.000	0.139	0.861
I20.8 Other forms of angina pectoris	0.000	0.156	0.844
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.166	0.834
I22 Subsequent myocardial infarction	0.000	0.201	0.799
I21.9 Acute myocardial infarction, unspecified	0.000	0.229	0.771
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.250	0.750
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.270	0.730
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I25.3 Aneurysm of heart	0.000	0.294	0.706
I25.4 Coronary artery aneurysm	0.000	0.312	0.688
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.315	0.685
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.318	0.682
I23 Certain current complications following acute myocardial infarction	0.000	0.334	0.666
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.336	0.664
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.387	0.613
I21.4 Acute subendocardial myocardial infarction	0.000	0.411	0.589
I22.8 Subsequent myocardial infarction of other sites	0.000	0.452	0.548
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.474	0.526
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.478	0.522
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.522	0.477
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.522	0.477
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.522	0.477
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.522	0.477
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.522	0.477
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.522	0.477
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.522	0.477
I23.8 Other current complications following acute myocardial infarction	0.000	0.556	0.443
I20.1 Angina pectoris with documented spasm	0.001	0.615	0.384
I24 Other acute ischaemic heart diseases	0.000	0.666	0.334
I20.0 Unstable angina	0.000	0.684	0.316
I24.1 Dressler's syndrome	0.000	0.760	0.239
H40.1 Primary open-angle glaucoma	0.208	0.792	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.799	0.201
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.811	0.189
H40 Glaucoma	0.185	0.815	0.000
H40.9 Glaucoma, unspecified	0.178	0.822	0.000
Chapter IX Diseases of the circulatory system	0.000	0.825	0.175
I60-I69 Cerebrovascular diseases	0.000	0.827	0.173
I63 Cerebral infarction	0.000	0.835	0.165
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.839	0.161
I63.9 Cerebral infarction, unspecified	0.000	0.847	0.153
I65.2 Occlusion and stenosis of carotid artery	0.000	0.848	0.152
H40.8 Other glaucoma	0.151	0.849	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.853	0.147
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.855	0.145
H40.5 Glaucoma secondary to other eye disorders	0.142	0.858	0.000
I62 Other nontraumatic intracranial haemorrhage	0.000	0.858	0.142
I61 Intracerebral haemorrhage	0.000	0.860	0.140
H40.0 Glaucoma suspect	0.137	0.863	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.864	0.136
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.865	0.135
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.867	0.133
H40.6 Glaucoma secondary to drugs	0.133	0.867	0.000
H40.4 Glaucoma secondary to eye inflammation	0.133	0.867	0.000
H40.3 Glaucoma secondary to eye trauma	0.133	0.867	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.869	0.131
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.872	0.128
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.873	0.127
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.874	0.126
I00-I02 Acute rheumatic fever	0.000	0.875	0.125
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.876	0.124
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.876	0.124
I24.8 Other forms of acute ischaemic heart disease	0.000	0.878	0.122
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.881	0.119
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.881	0.119
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.881	0.119
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.884	0.115
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.884	0.115
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.884	0.115
I65.1 Occlusion and stenosis of basilar artery	0.000	0.884	0.115
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.884	0.115
I69.3 Sequelae of cerebral infarction	0.000	0.888	0.112
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.890	0.109
I99 Other and unspecified disorders of circulatory system	0.000	0.891	0.109
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.891	0.109
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.892	0.108
I73 Other peripheral vascular diseases	0.000	0.894	0.106
I74 Arterial embolism and thrombosis	0.000	0.894	0.106
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.894	0.106
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.895	0.105
I61.8 Other intracerebral haemorrhage	0.000	0.896	0.104
I85 Oesophageal varices	0.000	0.897	0.103
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.897	0.103
I62.1 Nontraumatic extradural haemorrhage	0.000	0.898	0.102
I77 Other disorders of arteries and arterioles	0.000	0.899	0.101
I73.9 Peripheral vascular disease, unspecified	0.000	0.899	0.101
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.900	0.100
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.900	0.100
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.900	0.100
I81 Portal vein thrombosis	0.000	0.900	0.100
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.902	0.097
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.903	0.097
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.903	0.097
I95 Hypotension	0.000	0.903	0.097
I78 Diseases of capillaries	0.000	0.903	0.097
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.904	0.096
I72 Other aneurysm	0.000	0.906	0.094
I85.9 Oesophageal varices without bleeding	0.000	0.907	0.093
I63.8 Other cerebral infarction	0.000	0.908	0.092
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.908	0.092
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.909	0.091
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.909	0.091
I02 Rheumatic chorea	0.000	0.910	0.090
I01 Rheumatic fever with heart involvement	0.000	0.910	0.090
I00 Rheumatic fever without mention of heart involvement	0.000	0.910	0.090
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.911	0.089
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.911	0.089
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.911	0.089
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.911	0.089
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.911	0.089
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.911	0.089
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.911	0.089
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.911	0.089
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.911	0.089
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.911	0.089
I68.0 Cerebral amyloid angiopathy	0.000	0.911	0.089
I85.0 Oesophageal varices with bleeding	0.000	0.911	0.089
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.911	0.088
I86 Varicose veins of other sites	0.000	0.911	0.088
I71 Aortic aneurysm and dissection	0.000	0.912	0.088
I70 Atherosclerosis	0.000	0.914	0.085
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.917	0.082
I88 Nonspecific lymphadenitis	0.000	0.919	0.081
H40.2 Primary angle-closure glaucoma	0.080	0.920	0.000
I95.1 Orthostatic hypotension	0.000	0.920	0.080
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.920	0.080
I74.8 Embolism and thrombosis of other arteries	0.000	0.920	0.079
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.921	0.079
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.921	0.079
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.921	0.079
I98.0 Cardiovascular syphilis	0.000	0.921	0.079
I95.2 Hypotension due to drugs	0.000	0.922	0.078
I72.4 Aneurysm of artery of lower extremity	0.000	0.922	0.078
H40-H42 Glaucoma	0.077	0.922	0.000
I77.1 Stricture of artery	0.000	0.923	0.077
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.923	0.076
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.923	0.076
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.923	0.076
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.923	0.076
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.924	0.076
I77.8 Other specified disorders of arteries and arterioles	0.000	0.925	0.075
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.925	0.075
I73.8 Other specified peripheral vascular diseases	0.000	0.925	0.074
I95.8 Other hypotension	0.000	0.926	0.074
Chapter XX External causes of morbidity and mortality	0.074	0.926	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.927	0.073
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.073	0.927	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.927	0.073
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.927	0.073
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.927	0.073
I77.5 Necrosis of artery	0.000	0.927	0.073
I77.4 Coeliac artery compression syndrome	0.000	0.927	0.073
I77.3 Arterial fibromuscular dysplasia	0.000	0.927	0.073
I77.2 Rupture of artery	0.000	0.927	0.073
I77.0 Arteriovenous fistula, acquired	0.000	0.927	0.073
I95.0 Idiopathic hypotension	0.000	0.927	0.073
I86.4 Gastric varices	0.000	0.927	0.073
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.070	0.930	0.000
I86.1 Scrotal varices	0.000	0.930	0.070
I78.9 Disease of capillaries, unspecified	0.000	0.930	0.069
I78.8 Other diseases of capillaries	0.000	0.930	0.069
W00-W19 Falls	0.069	0.931	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.931	0.069
W20-W49 Exposure to inanimate mechanical forces	0.069	0.931	0.000
I87 Other disorders of veins	0.000	0.931	0.069
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.069	0.931	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.932	0.068
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.932	0.068
I72.2 Aneurysm of renal artery	0.000	0.932	0.068
I72.1 Aneurysm of artery of upper extremity	0.000	0.932	0.068
I72.0 Aneurysm of carotid artery	0.000	0.934	0.066
Y52 Agents primarily affecting the cardiovascular system	0.066	0.934	0.000
I72.3 Aneurysm of iliac artery	0.000	0.934	0.066
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.935	0.065
I79.1 Aortitis in diseases classified elsewhere	0.000	0.935	0.065
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.935	0.065
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.935	0.065
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.935	0.065
I01.8 Other acute rheumatic heart disease	0.000	0.935	0.065
I01.2 Acute rheumatic myocarditis	0.000	0.935	0.065
I01.1 Acute rheumatic endocarditis	0.000	0.935	0.065
I01.0 Acute rheumatic pericarditis	0.000	0.935	0.065
I02.9 Rheumatic chorea without heart involvement	0.000	0.935	0.065
I02.0 Rheumatic chorea with heart involvement	0.000	0.935	0.065
Z95.1 Presence of aortocoronary bypass graft	0.000	0.935	0.065
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.935	0.065
W49 Exposure to other and unspecified inanimate mechanical forces	0.064	0.935	0.000
I78.1 Naevus, nonneoplastic	0.000	0.936	0.064
I72.8 Aneurysm of other specified arteries	0.000	0.936	0.064
I86.3 Vulval varices	0.000	0.936	0.064
I86.2 Pelvic varices	0.000	0.936	0.064
I86.0 Sublingual varices	0.000	0.936	0.064
X40-X49 Accidental poisoning by and exposure to noxious substances	0.063	0.937	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.937	0.063
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.937	0.063
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.937	0.063
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.937	0.063
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.937	0.063
Y85 Sequelae of transport accidents	0.063	0.937	0.000
I77.6 Arteritis, unspecified	0.000	0.938	0.062
X50-X57 Overexertion, travel and privation	0.062	0.938	0.000
W08 Fall involving other furniture	0.062	0.938	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.938	0.062
I70.9 Generalised and unspecified atherosclerosis	0.000	0.938	0.061
I70.8 Atherosclerosis of other arteries	0.000	0.938	0.061
I70.1 Atherosclerosis of renal artery	0.000	0.938	0.061
Y42.7 Androgens and anabolic congeners	0.061	0.939	0.000
I83 Varicose veins of lower extremities	0.008	0.939	0.052
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.939	0.060
W50-W64 Exposure to animate mechanical forces	0.060	0.939	0.000
I72.9 Aneurysm of unspecified site	0.000	0.939	0.060
W49.9 Unspecified place	0.060	0.940	0.000
Y86 Sequelae of other accidents	0.060	0.940	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.940	0.060
Y10-Y34 Event of undetermined intent	0.060	0.940	0.000
X10-X19 Contact with heat and hot substances	0.060	0.940	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.059	0.941	0.000
Y57 Other and unspecified drugs and medicaments	0.059	0.941	0.000
Y42.1 Thyroid hormones and substitutes	0.059	0.941	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.059	0.941	0.000
I70.0 Atherosclerosis of aorta	0.000	0.941	0.059
Y59 Other and unspecified vaccines and biological substances	0.059	0.941	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.058	0.942	0.000
I88.8 Other nonspecific lymphadenitis	0.000	0.942	0.058
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.942	0.058
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.942	0.058
V01-V09 Pedestrian injured in transport accident	0.058	0.942	0.000
Y85.0 Sequelae of motor-vehicle accident	0.058	0.942	0.000
W45 Foreign body or object entering through skin	0.058	0.942	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.058	0.942	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.057	0.942	0.000
I86.8 Varicose veins of other specified sites	0.000	0.943	0.057
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.943	0.057
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.057	0.943	0.000
W22 Striking against or struck by other objects	0.056	0.944	0.000
W17 Other fall from one level to another	0.056	0.944	0.000
H42 Glaucoma in diseases classified elsewhere	0.056	0.944	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.056	0.944	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.056	0.944	0.000
Y40 Systemic antibiotics	0.056	0.944	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.945	0.055
I82 Other venous embolism and thrombosis	0.000	0.945	0.055
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.945	0.055
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.055	0.945	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.945	0.054
I97.0 Postcardiotomy syndrome	0.000	0.945	0.054
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.945	0.055
I60 Subarachnoid haemorrhage	0.003	0.945	0.051
W13 Fall from, out of or through building or structure	0.054	0.946	0.000
I67 Other cerebrovascular diseases	0.000	0.946	0.054
W03 Other fall on same level due to collision with, or pushing by, another person	0.054	0.946	0.000
W08.9 Unspecified place	0.054	0.946	0.000
W14 Fall from tree	0.054	0.946	0.000
I89.1 Lymphangitis	0.000	0.946	0.054
W11 Fall on and from ladder	0.054	0.946	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.054	0.946	0.000
Y43 Primarily systemic agents	0.054	0.946	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.946	0.054
X49.9 Unspecified place	0.054	0.946	0.000
Y00-Y09 Assault	0.054	0.946	0.000
Y88 Sequelae of surgical and medical care as external cause	0.054	0.946	0.000
X51 Travel and motion	0.054	0.946	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.053	0.946	0.000
Y35-Y36 Legal intervention and operations of war	0.053	0.947	0.000
X85-X99 Assault	0.053	0.947	0.000
X30-X39 Exposure to forces of nature	0.053	0.947	0.000
X00-X09 Exposure to smoke, fire and flames	0.053	0.947	0.000
W75-W84 Other accidental threats to breathing	0.053	0.947	0.000
W65-W74 Accidental drowning and submersion	0.053	0.947	0.000
V98-V99 Other and unspecified transport accidents	0.053	0.947	0.000
V95-V97 Air and space transport accidents	0.053	0.947	0.000
V90-V94 Water transport accidents	0.053	0.947	0.000
V70-V79 Bus occupant injured in transport accident	0.053	0.947	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.053	0.947	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.053	0.947	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.053	0.947	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.053	0.947	0.000
V20-V29 Motorcycle rider injured in transport accident	0.053	0.947	0.000
Y58 Bacterial vaccines	0.053	0.947	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.053	0.947	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.053	0.947	0.000
W05 Fall involving wheelchair	0.053	0.947	0.000
X20-X29 Contact with venomous animals and plants	0.052	0.948	0.000
W25 Contact with sharp glass	0.052	0.948	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.052	0.948	0.000
W55 Bitten or struck by other mammals	0.052	0.948	0.000
Y48 Anaesthetics and therapeutic gases	0.052	0.948	0.000
I71.0 Dissection of aorta [any part]	0.000	0.949	0.051
W15 Fall from cliff	0.051	0.949	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.949	0.051
I28 Other diseases of pulmonary vessels	0.000	0.949	0.051
W18 Other fall on same level	0.051	0.949	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.051	0.949	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.050	0.949	0.000
Y52.1 Calcium-channel blockers	0.050	0.950	0.000
V40-V49 Car occupant injured in transport accident	0.050	0.950	0.000
Y41.5 Antiviral drugs	0.050	0.950	0.000
W49.0 Home	0.050	0.950	0.000
W08.0 Home	0.050	0.950	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.050	0.950	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.050	0.950	0.000
W12 Fall on and from scaffolding	0.050	0.950	0.000
W09 Fall involving playground equipment	0.050	0.950	0.000
W04 Fall while being carried or supported by other persons	0.050	0.950	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.050	0.950	0.000
W00 Fall on same level involving ice and snow	0.050	0.950	0.000
Y28 Contact with sharp object, undetermined intent	0.050	0.950	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.050	0.950	0.000
W46 Contact with hypodermic needle	0.050	0.950	0.000
W43 Exposure to vibration	0.050	0.950	0.000
W42 Exposure to noise	0.050	0.950	0.000
W41 Exposure to high-pressure jet	0.050	0.950	0.000
W40 Explosion of other materials	0.050	0.950	0.000
W39 Discharge of firework	0.050	0.950	0.000
W38 Explosion and rupture of other specified pressurised devices	0.050	0.950	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.050	0.950	0.000
W36 Explosion and rupture of gas cylinder	0.050	0.950	0.000
W35 Explosion and rupture of boiler	0.050	0.950	0.000
W34 Discharge from other and unspecified firearms	0.050	0.950	0.000
W33 Rifle, shotgun and larger firearm discharge	0.050	0.950	0.000
W32 Handgun discharge	0.050	0.950	0.000
W31 Contact with other and unspecified machinery	0.050	0.950	0.000
W30 Contact with agricultural machinery	0.050	0.950	0.000
W28 Contact with powered lawn mower	0.050	0.950	0.000
W27 Contact with nonpowered hand tool	0.050	0.950	0.000
W26 Contact with knife, sword or dagger	0.050	0.950	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.050	0.950	0.000
Y40.9 Systemic antibiotic, unspecified	0.050	0.950	0.000
I87.9 Disorder of vein, unspecified	0.000	0.950	0.049
I87.0 Postphlebitic syndrome	0.000	0.950	0.049
Y42.0 Glucocorticoids and synthetic analogs	0.050	0.950	0.000
Y89 Sequelae of other external causes	0.049	0.950	0.000
W45.8 Other specified place	0.049	0.950	0.000
Y42.9 Other and unspecified hormone antagonists	0.049	0.950	0.000
Y42.4 Oral contraceptives	0.049	0.950	0.000
Y42.2 Antithyroid drugs	0.049	0.950	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.951	0.049
Y46 Antiepileptics and anti-Parkinsonism drugs	0.049	0.951	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.951	0.049
X16 Contact with hot heating appliances, radiators and pipes	0.049	0.951	0.000
W02.9 Unspecified place	0.049	0.951	0.000
W20 Struck by thrown, projected or falling object	0.048	0.951	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.048	0.952	0.000
Y59.3 Immunoglobulin	0.048	0.952	0.000
V80-V89 Other land transport accidents	0.048	0.952	0.000
I87.1 Compression of vein	0.000	0.952	0.048
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.048	0.952	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.047	0.952	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.047	0.952	0.000
Y52.7 Peripheral vasodilators	0.047	0.952	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.001	0.953	0.046
Y57.9 Drug or medicament, unspecified	0.047	0.953	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.047	0.953	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.047	0.953	0.000
W22.5 Trade and service area	0.047	0.953	0.000
V02 Pedestrian injured in collision with two- or three-wheeled motor vehicle	0.047	0.953	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.047	0.953	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.047	0.953	0.000
W06 Fall involving bed	0.047	0.953	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.003	0.953	0.044
W49.8 Other specified place	0.046	0.953	0.000
W49.7 Farm	0.046	0.953	0.000
W49.6 Industrial and construction area	0.046	0.953	0.000
W49.5 Trade and service area	0.046	0.953	0.000
W49.4 Street and highway	0.046	0.953	0.000
W49.3 Sports and athletics area	0.046	0.953	0.000
W49.2 School, other institution and public administrative area	0.046	0.953	0.000
W49.1 Residential institution	0.046	0.953	0.000
W21 Striking against or struck by sports equipment	0.046	0.954	0.000
Y57.5 X-ray contrast media	0.046	0.954	0.000
Y54.4 Loop [high-ceiling] diuretics	0.046	0.954	0.000
W23.2 School, other institution and public administrative area	0.046	0.954	0.000
W07 Fall involving chair	0.046	0.954	0.000
X48 Accidental poisoning by and exposure to pesticides	0.046	0.954	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.046	0.954	0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.046	0.954	0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.046	0.954	0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system	0.046	0.954	0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.046	0.954	0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.046	0.954	0.000
W55.0 Home	0.046	0.954	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.045	0.954	0.000
W22.2 School, other institution and public administrative area	0.045	0.954	0.000
I05-I09 Chronic rheumatic heart diseases	0.001	0.955	0.045
Y54.5 Other diuretics	0.045	0.955	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.955	0.045
I67.2 Cerebral atherosclerosis	0.000	0.955	0.045
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.045	0.955	0.000
X45 Accidental poisoning by and exposure to alcohol	0.045	0.955	0.000
X12 Contact with other hot fluids	0.045	0.955	0.000
X57 Unspecified privation	0.045	0.955	0.000
X54 Lack of water	0.045	0.955	0.000
X53 Lack of food	0.045	0.955	0.000
X52 Prolonged stay in weightless environment	0.045	0.955	0.000
X50 Overexertion and strenuous or repetitive movements	0.045	0.955	0.000
W08.8 Other specified place	0.044	0.955	0.000
W08.7 Farm	0.044	0.955	0.000
W08.6 Industrial and construction area	0.044	0.955	0.000
W08.5 Trade and service area	0.044	0.955	0.000
W08.4 Street and highway	0.044	0.955	0.000
W08.3 Sports and athletics area	0.044	0.955	0.000
W08.2 School, other institution and public administrative area	0.044	0.955	0.000
W08.1 Residential institution	0.044	0.955	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.956	0.044
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.956	0.044
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.956	0.044
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.956	0.044
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.956	0.044
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.956	0.044
Y51 Drugs primarily affecting the autonomic nervous system	0.044	0.956	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.956	0.044
Y54.8 Agents affecting uric acid metabolism	0.044	0.956	0.000
X51.8 Other specified place	0.044	0.956	0.000
W51 Striking against or bumped into by another person	0.044	0.956	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.956	0.044
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.956	0.044
W17.5 Trade and service area	0.044	0.956	0.000
X51.9 Unspecified place	0.044	0.956	0.000
W13.9 Unspecified place	0.044	0.956	0.000
Y40.8 Other systemic antibiotics	0.044	0.956	0.000
I97.1 Other functional disturbances following cardiac surgery	0.000	0.956	0.043
W64 Exposure to other and unspecified animate mechanical forces	0.043	0.956	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.043	0.956	0.000
W59 Bitten or crushed by other reptiles	0.043	0.956	0.000
W58 Bitten or struck by crocodile or alligator	0.043	0.956	0.000
W56 Contact with marine animal	0.043	0.956	0.000
W54 Bitten or struck by dog	0.043	0.956	0.000
W53 Bitten by rat	0.043	0.956	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.043	0.956	0.000
W03.9 Unspecified place	0.044	0.956	0.000
V10-V19 Pedal cyclist injured in transport accident	0.043	0.957	0.000
I10-I15 Hypertensive diseases	0.000	0.957	0.043
W17.4 Street and highway	0.043	0.957	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.043	0.957	0.000
Y34 Unspecified event, undetermined intent	0.043	0.957	0.000
Y33 Other specified events, undetermined intent	0.043	0.957	0.000
Y32 Crashing of motor vehicle, undetermined intent	0.043	0.957	0.000
Y31 Falling, lying or running before or into moving object, undetermined intent	0.043	0.957	0.000
Y30 Falling, jumping or pushed from a high place, undetermined intent	0.043	0.957	0.000
Y29 Contact with blunt object, undetermined intent	0.043	0.957	0.000
Y27 Contact with steam, hot vapours and hot objects, undetermined intent	0.043	0.957	0.000
Y26 Exposure to smoke, fire and flames, undetermined intent	0.043	0.957	0.000
Y25 Contact with explosive material, undetermined intent	0.043	0.957	0.000
Y24 Other and unspecified firearm discharge, undetermined intent	0.043	0.957	0.000
Y23 Rifle, shotgun and larger firearm discharge, undetermined intent	0.043	0.957	0.000
Y22 Handgun discharge, undetermined intent	0.043	0.957	0.000
Y21 Drowning and submersion, undetermined intent	0.043	0.957	0.000
Y20 Hanging, strangulation and suffocation, undetermined intent	0.043	0.957	0.000
Y19 Poisoning by and exposure to other and unspecified chemicals and noxious substances, undetermined intent	0.043	0.957	0.000
Y18 Poisoning by and exposure to pesticides, undetermined intent	0.043	0.957	0.000
Y17 Poisoning by and exposure to other gases and vapours, undetermined intent	0.043	0.957	0.000
Y16 Poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours, undetermined intent	0.043	0.957	0.000
Y15 Poisoning by and exposure to alcohol, undetermined intent	0.043	0.957	0.000
Y14 Poisoning by and exposure to other and unspecified drugs, medicaments and biological substances, undetermined intent	0.043	0.957	0.000
Y13 Poisoning by and exposure to other drugs acting on the autonomic nervous system, undetermined intent	0.043	0.957	0.000
Y12 Poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified, undetermined intent	0.043	0.957	0.000
Y11 Poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified, undetermined intent	0.043	0.957	0.000
Y10 Poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics, undetermined intent	0.043	0.957	0.000
X19 Contact with other and unspecified heat and hot substances	0.043	0.957	0.000
X18 Contact with other hot metals	0.043	0.957	0.000
X17 Contact with hot engines, machinery and tools	0.043	0.957	0.000
X15 Contact with hot household appliances	0.043	0.957	0.000
X14 Contact with hot air and gases	0.043	0.957	0.000
X13 Contact with steam and hot vapours	0.043	0.957	0.000
X11 Contact with hot tap-water	0.043	0.957	0.000
W14.9 Unspecified place	0.043	0.957	0.000
V27 Motorcycle rider injured in collision with fixed or stationary object	0.043	0.957	0.000
W11.6 Industrial and construction area	0.043	0.957	0.000
Y54.9 Mineral salts, not elsewhere classified	0.043	0.957	0.000
Y54.7 Agents affecting calcification	0.043	0.957	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.043	0.957	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.043	0.957	0.000
Y54.0 Mineralocorticoids	0.043	0.957	0.000
X10 Contact with hot drinks, food, fats and cooking oils	0.043	0.957	0.000
Y28.9 Unspecified place	0.043	0.957	0.000
Y57.7 Vitamins, not elsewhere classified	0.042	0.957	0.000
Y57.6 Other diagnostic agents	0.042	0.957	0.000
Y57.4 Pharmaceutical excipients	0.042	0.957	0.000
Y57.3 Alcohol deterrents	0.042	0.957	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.042	0.957	0.000
Y57.1 Lipotropic drugs	0.042	0.957	0.000
Y57.0 Appetite depressants [anorectics]	0.042	0.957	0.000
I82.2 Embolism and thrombosis of vena cava	0.000	0.957	0.042
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.042	0.958	0.000
Y41.4 Anthelminthics	0.042	0.958	0.000
Y41.3 Other antiprotozoal drugs	0.042	0.958	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.042	0.958	0.000
Y41.1 Antimycobacterial drugs	0.042	0.958	0.000
Y41.0 Sulphonamides	0.042	0.958	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.958	0.042

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations