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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12892019
log Bayes Factor = 13.1568
Chromosome 14   position 25,759,476  (GRCh37) Explore rs12892019 on Ensembl!
Variant rs12892019 is part of Cluster X0137

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.996 0.004 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
Z86.7 Personal history of diseases of the circulatory system
0.994 0.006 0.000
Z86 Personal history of certain other diseases
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
O36 Maternal care for other known or suspected foetal problems
0.989 0.011 0.000
I63 Cerebral infarction
0.988 0.012 0.000
S60-S69 Injuries to the wrist and hand
0.987 0.013 0.000
I67 Other cerebrovascular diseases
0.984 0.016 0.000
I30-I52 Other forms of heart disease
0.984 0.016 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.982 0.018 0.000
Z92 Personal history of medical treatment
0.981 0.019 0.000
Z93 Artificial opening status
0.979 0.021 0.000
I50 Heart failure
0.975 0.025 0.000
I67.8 Other specified cerebrovascular diseases
0.972 0.028 0.000
K70-K77 Diseases of liver
0.971 0.029 0.000
K80 Cholelithiasis
0.968 0.032 0.000
I63.9 Cerebral infarction, unspecified
0.967 0.033 0.000
I50.0 Congestive heart failure
0.967 0.033 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.965 0.035 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.961 0.039 0.000
T81 Complications of procedures, not elsewhere classified
0.960 0.040 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.950 0.050 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.949 0.051 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.948 0.052 0.000
Z93.2 Ileostomy status
0.941 0.059 0.000
Chapter VI Diseases of the nervous system
0.938 0.062 0.000
O47 False labour
0.934 0.066 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.934 0.066 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.931 0.069 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.928 0.072 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.928 0.072 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.924 0.076 0.000
Z83 Family history of other specific disorders
0.918 0.082 0.000
K11 Diseases of salivary glands
0.917 0.083 0.000
Z92.3 Personal history of irradiation
0.916 0.084 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.916 0.084 0.000
O36.8 Maternal care for other specified foetal problems
0.916 0.084 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.914 0.086 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.910 0.090 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.908 0.092 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.904 0.096 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.903 0.097 0.000
O80-O84 Delivery
0.903 0.097 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.901 0.099 0.000
S70-S79 Injuries to the hip and thigh
0.900 0.100 0.000
I67.9 Cerebrovascular disease, unspecified
0.900 0.100 0.000
G20-G26 Extrapyramidal and movement disorders
0.897 0.103 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.896 0.104 0.000
O36.5 Maternal care for poor foetal growth
0.893 0.107 0.000
K83 Other diseases of biliary tract
0.886 0.114 0.000
K70 Alcoholic liver disease
0.884 0.116 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.881 0.119 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.881 0.119 0.000
S64 Injury of nerves at wrist and hand level
0.880 0.120 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.879 0.121 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.872 0.128 0.000
Z03.1 Observation for suspected malignant neoplasm
0.872 0.128 0.000
K72 Hepatic failure, not elsewhere classified
0.870 0.130 0.000
M65-M68 Disorders of synovium and tendon
0.869 0.131 0.000
O30 Multiple gestation
0.866 0.134 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.864 0.136 0.000
Z12 Special screening examination for neoplasms
0.864 0.136 0.000
Z83.5 Family history of eye and ear disorders
0.863 0.137 0.000
Z94 Transplanted organ and tissue status
0.854 0.146 0.000
I26 Pulmonary embolism
0.854 0.146 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.854 0.146 0.000
K08 Other disorders of teeth and supporting structures
0.851 0.149 0.000
M65 Synovitis and tenosynovitis
0.851 0.149 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.851 0.149 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.851 0.149 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.851 0.149 0.000
Z93.3 Colostomy status
0.851 0.149 0.000
G20 Parkinson's disease
0.847 0.153 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.847 0.153 0.000
Z89 Acquired absence of limb
0.846 0.154 0.000
Z03.8 Observation for other suspected diseases and conditions
0.846 0.154 0.000
I45 Other conduction disorders
0.843 0.157 0.000
I27 Other pulmonary heart diseases
0.843 0.157 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.841 0.159 0.000
I71 Aortic aneurysm and dissection
0.837 0.163 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.836 0.164 0.000
G81 Hemiplegia
0.835 0.164 0.000
O80 Single spontaneous delivery
0.830 0.170 0.000
M65.3 Trigger finger
0.829 0.171 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.828 0.172 0.000
Z86.0 Personal history of other neoplasms
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.827 0.172 0.000
S61 Open wound of wrist and hand
0.827 0.173 0.000
K11.2 Sialoadenitis
0.827 0.173 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.825 0.175 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.825 0.175 0.000
S10-S19 Injuries to the neck
0.823 0.177 0.000
O47.0 False labour before 37 completed weeks of gestation
0.823 0.177 0.000
I42 Cardiomyopathy
0.823 0.177 0.000
K82 Other diseases of gallbladder
0.821 0.179 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.821 0.179 0.000
S40-S49 Injuries to the shoulder and upper arm
0.818 0.182 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.815 0.185 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.815 0.185 0.000
G90-G99 Other disorders of the nervous system
0.813 0.187 0.000
M65.34 Trigger finger-Hand
0.813 0.187 0.000
I69 Sequelae of cerebrovascular disease
0.809 0.191 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.806 0.194 0.000
K90-K93 Other diseases of the digestive system
0.806 0.194 0.000
S72 Fracture of femur
0.805 0.195 0.000
G81.9 Hemiplegia, unspecified
0.805 0.195 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.804 0.195 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.804 0.196 0.000
S68 Traumatic amputation of wrist and hand
0.802 0.198 0.000
K74 Fibrosis and cirrhosis of liver
0.801 0.199 0.000
K10 Other diseases of jaws
0.801 0.199 0.000
I51 Complications and ill-defined descriptions of heart disease
0.800 0.200 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.799 0.201 0.000
I65.2 Occlusion and stenosis of carotid artery
0.797 0.203 0.000
T92 Sequelae of injuries of upper limb
0.794 0.206 0.000
Z93.1 Gastrostomy status
0.793 0.207 0.000
I27.0 Primary pulmonary hypertension
0.793 0.207 0.000
I63.8 Other cerebral infarction
0.792 0.207 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.788 0.212 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.788 0.212 0.000
T81.9 Unspecified complication of procedure
0.787 0.213 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.787 0.213 0.000
S90-S99 Injuries to the ankle and foot
0.786 0.214 0.000
M70-M79 Other soft tissue disorders
0.786 0.214 0.000
I50.1 Left ventricular failure
0.786 0.214 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.781 0.219 0.000
O43 Placental disorders
0.780 0.220 0.000
O80.0 Spontaneous vertex delivery
0.780 0.220 0.000
S64.4 Injury of digital nerve of other finger
0.780 0.220 0.000
T93 Sequelae of injuries of lower limb
0.778 0.222 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.777 0.223 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.776 0.224 0.000
T42.4 Benzodiazepines
0.773 0.227 0.000
K07 Dentofacial anomalies [including malocclusion]
0.773 0.227 0.000
T90 Sequelae of injuries of head
0.771 0.229 0.000
O30.0 Twin pregnancy
0.770 0.230 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.767 0.233 0.000
O32.1 Maternal care for breech presentation
0.766 0.234 0.000
S61.0 Open wound of finger(s) without damage to nail
0.765 0.235 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.764 0.236 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.764 0.236 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.762 0.238 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.761 0.238 0.000
K11.1 Hypertrophy of salivary gland
0.761 0.239 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.758 0.242 0.000
Chapter I Certain infectious and parasitic diseases
0.757 0.243 0.000
K72.0 Acute and subacute hepatic failure
0.754 0.246 0.000
K70.9 Alcoholic liver disease, unspecified
0.754 0.246 0.000
Chapter X Diseases of the respiratory system
0.753 0.247 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.752 0.248 0.000
O36.9 Maternal care for foetal problem, unspecified
0.751 0.249 0.000
O44 Placenta praevia
0.751 0.249 0.000
T98 Sequelae of other and unspecified effects of external causes
0.750 0.250 0.000
T79-T79 Certain early complications of trauma
0.750 0.250 0.000
T86 Failure and rejection of transplanted organs and tissues
0.750 0.250 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.750 0.250 0.000
G70-G73 Diseases of myoneural junction and muscle
0.749 0.251 0.000
Z93.0 Tracheostomy status
0.749 0.251 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.745 0.255 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.744 0.256 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.743 0.257 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.742 0.258 0.000
K75 Other inflammatory liver diseases
0.742 0.258 0.000
G25 Other extrapyramidal and movement disorders
0.742 0.258 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.739 0.261 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.739 0.261 0.000
K01 Embedded and impacted teeth
0.738 0.262 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.737 0.263 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.737 0.263 0.000
O41 Other disorders of amniotic fluid and membranes
0.737 0.263 0.000
J90-J94 Other diseases of pleura
0.737 0.263 0.000
K70.3 Alcoholic cirrhosis of liver
0.736 0.264 0.000
M80-M85 Disorders of bone density and structure
0.735 0.264 0.000
K83.8 Other specified diseases of biliary tract
0.731 0.269 0.000
K11.9 Disease of salivary gland, unspecified
0.730 0.270 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.730 0.270 0.000
K02 Dental caries
0.728 0.272 0.000
K83.1 Obstruction of bile duct
0.728 0.272 0.000
I71.0 Dissection of aorta [any part]
0.728 0.272 0.000
K09 Cysts of oral region, not elsewhere classified
0.726 0.274 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.724 0.276 0.000
Z92.0 Personal history of contraception
0.724 0.276 0.000
K80.4 Calculus of bile duct with cholecystitis
0.721 0.279 0.000
I49 Other cardiac arrhythmias
0.720 0.280 0.000
S67 Crushing injury of wrist and hand
0.718 0.282 0.000
O21 Excessive vomiting in pregnancy
0.717 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
K72.9 Hepatic failure, unspecified
0.717 0.283 0.000
S60 Superficial injury of wrist and hand
0.717 0.283 0.000
Chapter XX External causes of morbidity and mortality
0.717 0.283 0.000
O45 Premature separation of placenta [abruptio placentae]
0.717 0.283 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.717 0.283 0.000
O33 Maternal care for known or suspected disproportion
0.717 0.283 0.000
O31 Complications specific to multiple gestation
0.717 0.283 0.000
O40 Polyhydramnios
0.717 0.283 0.000
M86-M90 Other osteopathies
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.715 0.284 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.715 0.285 0.000
Z94.4 Liver transplant status
0.714 0.286 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.288 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.288 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.711 0.288 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.288 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.288 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.288 0.000
T36 Poisoning by systemic antibiotics
0.711 0.288 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.711 0.289 0.000
Z89.6 Acquired absence of leg above knee
0.711 0.289 0.000
T40.2 Other opioids
0.711 0.289 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.710 0.290 0.000
K82.4 Cholesterolosis of gallbladder
0.710 0.290 0.000
I70 Atherosclerosis
0.710 0.290 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.709 0.291 0.000
O36.4 Maternal care for intra-uterine death
0.709 0.291 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.709 0.291 0.000
O36.2 Maternal care for hydrops foetalis
0.709 0.291 0.000
O36.1 Maternal care for other isoimmunisation
0.709 0.291 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.709 0.291 0.000
S70 Superficial injury of hip and thigh
0.709 0.291 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.709 0.291 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.708 0.292 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.708 0.292 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.708 0.292 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.708 0.292 0.000
S69 Other and unspecified injuries of wrist and hand
0.708 0.292 0.000
S65 Injury of blood vessels at wrist and hand level
0.708 0.292 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.708 0.292 0.000
K83.0 Cholangitis
0.706 0.294 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.706 0.294 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.706 0.294 0.000
I67.5 Moyamoya disease
0.706 0.294 0.000
I67.4 Hypertensive encephalopathy
0.706 0.294 0.000
I67.3 Progressive vascular leukoencephalopathy
0.706 0.294 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.706 0.294 0.000
K05 Gingivitis and periodontal diseases
0.706 0.294 0.000
I52 Other heart disorders in diseases classified elsewhere
0.705 0.295 0.000
I48 Atrial fibrillation and flutter
0.705 0.295 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.705 0.295 0.000
I41 Myocarditis in diseases classified elsewhere
0.705 0.295 0.000
I40 Acute myocarditis
0.705 0.295 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.705 0.295 0.000
I37 Pulmonary valve disorders
0.705 0.295 0.000
I36 Nonrheumatic tricuspid valve disorders
0.705 0.295 0.000
I33 Acute and subacute endocarditis
0.705 0.295 0.000
I32 Pericarditis in diseases classified elsewhere
0.705 0.295 0.000
I30 Acute pericarditis
0.705 0.295 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.704 0.295 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.704 0.296 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.704 0.296 0.000
Z92.9 Personal history of medical treatment, unspecified
0.703 0.296 0.000
Z92.8 Personal history of other medical treatment
0.703 0.296 0.000
Z92.5 Personal history of rehabilitation measures
0.703 0.296 0.000
Z93.9 Artificial opening status, unspecified
0.702 0.298 0.000
Z93.8 Other artificial opening status
0.702 0.298 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.702 0.298 0.000
O23 Infections of genito-urinary tract in pregnancy
0.701 0.299 0.000
I62 Other nontraumatic intracranial haemorrhage
0.701 0.299 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.700 0.300 0.000
I45.9 Conduction disorder, unspecified
0.700 0.300 0.000
I35 Nonrheumatic aortic valve disorders
0.699 0.301 0.000
T43.2 Other and unspecified antidepressants
0.699 0.301 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.699 0.301 0.000
Z93.6 Other artificial openings of urinary tract status
0.699 0.301 0.000
I78 Diseases of capillaries
0.697 0.303 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.697 0.303 0.000
K77 Liver disorders in diseases classified elsewhere
0.696 0.304 0.000
K73 Chronic hepatitis, not elsewhere classified
0.696 0.304 0.000
K71 Toxic liver disease
0.696 0.304 0.000
L20-L30 Dermatitis and eczema
0.696 0.304 0.000
S00-S09 Injuries to the head
0.696 0.304 0.000
S72.0 Fracture of neck of femur
0.695 0.305 0.000
S61.7 Multiple open wounds of wrist and hand
0.695 0.305 0.000
K85 Acute pancreatitis
0.694 0.306 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.694 0.306 0.000
K80.3 Calculus of bile duct with cholangitis
0.694 0.306 0.000
T82.1 Mechanical complication of cardiac electronic device
0.694 0.306 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.692 0.308 0.000
K03 Other diseases of hard tissues of teeth
0.692 0.308 0.000
K00 Disorders of tooth development and eruption
0.692 0.308 0.000
K11.5 Sialolithiasis
0.690 0.310 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.690 0.310 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.689 0.311 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.689 0.311 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.689 0.311 0.000
T82.3 Mechanical complication of other vascular grafts
0.689 0.311 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.689 0.311 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.688 0.312 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.688 0.312 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.688 0.312 0.000
M79.8 Other specified soft tissue disorders
0.687 0.313 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.687 0.313 0.000
K08.3 Retained dental root
0.685 0.315 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.682 0.318 0.000
O46.9 Antepartum haemorrhage, unspecified
0.682 0.318 0.000
L40-L45 Papulosquamous disorders
0.682 0.318 0.000
O20 Haemorrhage in early pregnancy
0.681 0.319 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.680 0.320 0.000
T95 Sequelae of burns, corrosions and frostbite
0.680 0.320 0.000
T91 Sequelae of injuries of neck and trunk
0.680 0.320 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.680 0.320 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.680 0.320 0.000
Chapter V Mental and behavioural disorders
0.680 0.320 0.000
K70.4 Alcoholic hepatic failure
0.680 0.320 0.000
I28 Other diseases of pulmonary vessels
0.680 0.320 0.000
Z94.0 Kidney transplant status
0.680 0.320 0.000
Z93.5 Cystostomy status
0.678 0.322 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.676 0.324 0.000
K40-K46 Hernia
0.676 0.324 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.676 0.324 0.000
I61 Intracerebral haemorrhage
0.674 0.325 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.674 0.325 0.000
S80-S89 Injuries to the knee and lower leg
0.674 0.326 0.000
Z29 Need for other prophylactic measures
0.674 0.326 0.000
M91-M94 Chondropathies
0.673 0.326 0.000
G95 Other diseases of spinal cord
0.673 0.327 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.673 0.327 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.672 0.328 0.000
K76 Other diseases of liver
0.672 0.328 0.000
J90 Pleural effusion, not elsewhere classified
0.672 0.328 0.000
M00-M03 Infectious arthropathies
0.671 0.328 0.000
O47.9 False labour, unspecified
0.671 0.329 0.000
O36.6 Maternal care for excessive foetal growth
0.671 0.329 0.000
I69.3 Sequelae of cerebral infarction
0.670 0.330 0.000
Z83.7 Family history of diseases of the digestive system
0.670 0.330 0.000
K90 Intestinal malabsorption
0.670 0.330 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.669 0.331 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.669 0.331 0.000
T92.1 Sequelae of fracture of arm
0.669 0.331 0.000
I44 Atrioventricular and left bundle-branch block
0.668 0.332 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.668 0.332 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.668 0.332 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.668 0.332 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.668 0.332 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.668 0.332 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.668 0.332 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.668 0.332 0.000
I77 Other disorders of arteries and arterioles
0.668 0.332 0.000
O16 Unspecified maternal hypertension
0.667 0.333 0.000
S72.1 Pertrochanteric fracture
0.667 0.333 0.000
Z97 Presence of other devices
0.667 0.333 0.000
Z22 Carrier of infectious disease
0.667 0.333 0.000
O42 Premature rupture of membranes
0.666 0.334 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.666 0.334 0.000
T43.9 Psychotropic drug, unspecified
0.665 0.334 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.665 0.334 0.000
T43.6 Psychostimulants with abuse potential
0.665 0.334 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.665 0.334 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.665 0.334 0.000
M05-M14 Inflammatory polyarthropathies
0.665 0.335 0.000
J92 Pleural plaque
0.665 0.335 0.000
I51.8 Other ill-defined heart diseases
0.664 0.336 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.664 0.336 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.663 0.337 0.000
Z10 Routine general health check-up of defined subpopulation
0.662 0.338 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.662 0.338 0.000
I45.6 Preexcitation syndrome
0.662 0.338 0.000
K80.8 Other cholelithiasis
0.661 0.339 0.000
K12 Stomatitis and related lesions
0.660 0.340 0.000
G80 Infantile cerebral palsy
0.660 0.340 0.000
G93 Other disorders of brain
0.660 0.340 0.000
I50.9 Heart failure, unspecified
0.660 0.340 0.000
Chapter VII Diseases of the eye and adnexa
0.660 0.340 0.000
Z83.6 Family history of diseases of the respiratory system
0.658 0.342 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.658 0.342 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.658 0.342 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.658 0.342 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.658 0.342 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.658 0.342 0.000
K11.8 Other diseases of salivary glands
0.658 0.342 0.000
K11.7 Disturbances of salivary secretion
0.658 0.342 0.000
K11.6 Mucocele of salivary gland
0.658 0.342 0.000
K11.4 Fistula of salivary gland
0.658 0.342 0.000
K11.3 Abscess of salivary gland
0.658 0.342 0.000
K11.0 Atrophy of salivary gland
0.658 0.342 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.657 0.342 0.000
O82 Single delivery by Caesarean section
0.657 0.343 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.657 0.343 0.000
Z03.0 Observation for suspected tuberculosis
0.657 0.343 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.657 0.343 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.656 0.344 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.655 0.345 0.000
O15 Eclampsia
0.655 0.345 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.655 0.345 0.000
I42.9 Cardiomyopathy, unspecified
0.655 0.345 0.000
K10.8 Other specified diseases of jaws
0.655 0.345 0.000
K13 Other diseases of lip and oral mucosa
0.653 0.347 0.000
S12 Fracture of neck
0.653 0.347 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.652 0.347 0.000
I72 Other aneurysm
0.652 0.347 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.651 0.349 0.000
S10 Superficial injury of neck
0.650 0.349 0.000
Z83.3 Family history of diabetes mellitus
0.650 0.350 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.649 0.351 0.000
S50-S59 Injuries to the elbow and forearm
0.648 0.352 0.000
O29 Complications of anaesthesia during pregnancy
0.647 0.352 0.000
O28 Abnormal findings on antenatal screening of mother
0.647 0.352 0.000
O24 Diabetes mellitus in pregnancy
0.647 0.352 0.000
O22 Venous complications in pregnancy
0.647 0.352 0.000
O25 Malnutrition in pregnancy
0.647 0.352 0.000
O84 Multiple delivery
0.647 0.353 0.000
O83 Other assisted single delivery
0.647 0.353 0.000
O81 Single delivery by forceps and vacuum extractor
0.647 0.353 0.000
B95-B98 Bacterial, viral and other infectious agents
0.647 0.353 0.000
S79 Other and unspecified injuries of hip and thigh
0.645 0.354 0.000
S78 Traumatic amputation of hip and thigh
0.645 0.354 0.000
S77 Crushing injury of hip and thigh
0.645 0.354 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.645 0.354 0.000
S75 Injury of blood vessels at hip and thigh level
0.645 0.354 0.000
S74 Injury of nerves at hip and thigh level
0.645 0.354 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.645 0.354 0.000
S71 Open wound of hip and thigh
0.645 0.354 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.645 0.355 0.000
S62 Fracture at wrist and hand level
0.645 0.355 0.000
G24 Dystonia
0.644 0.356 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.643 0.357 0.000
G23 Other degenerative diseases of basal ganglia
0.643 0.357 0.000
G21 Secondary Parkinsonism
0.643 0.357 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.643 0.357 0.000
G22 Parkinsonism in diseases classified elsewhere
0.643 0.357 0.000
M60-M63 Disorders of muscles
0.642 0.357 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.642 0.358 0.000
K43 Ventral hernia
0.642 0.358 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.642 0.358 0.000
O26.8 Other specified pregnancy-related conditions
0.641 0.359 0.000
Z89.4 Acquired absence of foot and ankle
0.641 0.359 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.639 0.360 0.000
T51 Toxic effect of alcohol
0.639 0.361 0.000
S43.0 Dislocation of shoulder joint
0.639 0.361 0.000
T66-T78 Other and unspecified effects of external causes
0.638 0.361 0.000
K74.0 Hepatic fibrosis
0.638 0.362 0.000
I42.0 Dilated cardiomyopathy
0.636 0.364 0.000
I46 Cardiac arrest
0.636 0.364 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.636 0.364 0.000
K07.6 Temporomandibular joint disorders
0.635 0.365 0.000
K83.9 Disease of biliary tract, unspecified
0.635 0.365 0.000
K83.5 Biliary cyst
0.635 0.365 0.000
K83.4 Spasm of sphincter of Oddi
0.635 0.365 0.000
K83.3 Fistula of bile duct
0.635 0.365 0.000
K83.2 Perforation of bile duct
0.635 0.365 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.635 0.365 0.000
I38 Endocarditis, valve unspecified
0.635 0.365 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.634 0.366 0.000
K70.1 Alcoholic hepatitis
0.634 0.366 0.000
K70.0 Alcoholic fatty liver
0.634 0.366 0.000
I51.4 Myocarditis, unspecified
0.633 0.367 0.000
K50-K52 Noninfective enteritis and colitis
0.632 0.368 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.632 0.368 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.632 0.368 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.632 0.368 0.000
I65.1 Occlusion and stenosis of basilar artery
0.632 0.368 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.632 0.368 0.000
Z73 Problems related to life-management difficulty
0.631 0.368 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.631 0.369 0.000
S64.8 Injury of other nerves at wrist and hand level
0.631 0.369 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.631 0.369 0.000
S64.3 Injury of digital nerve of thumb
0.631 0.369 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.631 0.369 0.000
S64.1 Injury of median nerve at wrist and hand level
0.631 0.369 0.000
I60 Subarachnoid haemorrhage
0.630 0.370 0.000
B15-B19 Viral hepatitis
0.630 0.370 0.000
G83 Other paralytic syndromes
0.630 0.370 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.629 0.371 0.000
Z89.5 Acquired absence of leg at or below knee
0.626 0.373 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.626 0.374 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.625 0.375 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.625 0.375 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.625 0.375 0.000
O34.6 Maternal care for abnormality of vagina
0.625 0.375 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.625 0.375 0.000
O34.4 Maternal care for other abnormalities of cervix
0.625 0.375 0.000
O34.3 Maternal care for cervical incompetence
0.625 0.375 0.000
O34.1 Maternal care for tumour of corpus uteri
0.625 0.375 0.000
O34.0 Maternal care for congenital malformation of uterus
0.625 0.375 0.000
J95-J99 Other diseases of the respiratory system
0.625 0.375 0.000
I42.2 Other hypertrophic cardiomyopathy
0.624 0.375 0.000
I45.1 Other and unspecified right bundle-branch block
0.624 0.376 0.000
K72.1 Chronic hepatic failure
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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