TreeWAS – Variant ID: rs13130255

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
S00-S09 Injuries to the head	0.999	0.001	0.000
S02 Fracture of skull and facial bones	0.995	0.005	0.000
S09 Other and unspecified injuries of head	0.987	0.013	0.000
S09.9 Unspecified injury of head	0.981	0.019	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.974	0.026	0.000
S02.4 Fracture of malar and maxillary bones	0.967	0.033	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.965	0.035	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.948	0.052	0.000
S70-S79 Injuries to the hip and thigh	0.945	0.055	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.943	0.057	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.940	0.060	0.000
S50-S59 Injuries to the elbow and forearm	0.939	0.061	0.000
S90-S99 Injuries to the ankle and foot	0.938	0.062	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.933	0.067	0.000
T42.4 Benzodiazepines	0.933	0.067	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.916	0.084	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.901	0.099	0.000
T17 Foreign body in respiratory tract	0.900	0.100	0.000
S06 Intracranial injury	0.896	0.104	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.887	0.113	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.886	0.114	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.875	0.125	0.000
T17.2 Foreign body in pharynx	0.871	0.129	0.000
S72 Fracture of femur	0.870	0.130	0.000
S91 Open wound of ankle and foot	0.859	0.141	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.857	0.143	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.839	0.161	0.000
S02.1 Fracture of base of skull	0.838	0.162	0.000
S40-S49 Injuries to the shoulder and upper arm	0.837	0.163	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.836	0.164	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.834	0.166	0.000
S50 Superficial injury of forearm	0.830	0.170	0.000
S02.3 Fracture of orbital floor	0.826	0.174	0.000
S02.8 Fractures of other skull and facial bones	0.821	0.179	0.000
S92 Fracture of foot, except ankle	0.819	0.181	0.000
T51 Toxic effect of alcohol	0.819	0.181	0.000
S52 Fracture of forearm	0.816	0.184	0.000
S72.0 Fracture of neck of femur	0.813	0.187	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.796	0.204	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.793	0.207	0.000
S91.3 Open wound of other parts of foot	0.783	0.217	0.000
S02.2 Fracture of nasal bones	0.782	0.218	0.000
S05 Injury of eye and orbit	0.777	0.223	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.775	0.224	0.000
S52.5 Fracture of lower end of radius	0.773	0.227	0.000
S72.00 Fracture of neck of femur (closed)	0.772	0.228	0.000
T36 Poisoning by systemic antibiotics	0.769	0.231	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.768	0.232	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.760	0.240	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.758	0.242	0.000
T00-T07 Injuries involving multiple body regions	0.756	0.244	0.000
S42 Fracture of shoulder and upper arm	0.751	0.249	0.000
S52.50 Fracture of lower end of radius (closed)	0.747	0.253	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.746	0.254	0.000
S70 Superficial injury of hip and thigh	0.746	0.254	0.000
S02.6 Fracture of mandible	0.741	0.259	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.740	0.260	0.000
S56 Injury of muscle and tendon at forearm level	0.739	0.261	0.000
T46.1 Calcium-channel blockers	0.738	0.261	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.738	0.261	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.738	0.262	0.000
S50.9 Superficial injury of forearm, unspecified	0.738	0.262	0.000
S71 Open wound of hip and thigh	0.730	0.269	0.000
T51.9 Alcohol, unspecified	0.730	0.270	0.000
S02.10 Fracture of base of skull (closed)	0.725	0.275	0.000
T42.1 Iminostilbenes	0.725	0.275	0.000
T40.6 Other and unspecified narcotics	0.725	0.275	0.000
S06.4 Epidural haemorrhage	0.721	0.279	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.721	0.279	0.000
T45.0 Antiallergic and antiemetic drugs	0.717	0.283	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
S08 Traumatic amputation of part of head	0.716	0.283	0.000
S07 Crushing injury of head	0.716	0.283	0.000
S04 Injury of cranial nerves	0.716	0.283	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.716	0.283	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.716	0.284	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.715	0.285	0.000
S02.7 Multiple fractures involving skull and facial bones	0.713	0.287	0.000
S09.7 Multiple injuries of head	0.708	0.292	0.000
S09.2 Traumatic rupture of ear drum	0.708	0.292	0.000
S09.1 Injury of muscle and tendon of head	0.708	0.292	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.708	0.292	0.000
Chapter V Mental and behavioural disorders	0.708	0.292	0.000
T56 Toxic effect of metals	0.707	0.293	0.000
S02.30 Fracture of orbital floor (closed)	0.705	0.295	0.000
S92.3 Fracture of metatarsal bone	0.700	0.300	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.700	0.300	0.000
F30-F39 Mood [affective] disorders	0.700	0.300	0.000
F31 Bipolar affective disorder	0.699	0.301	0.000
F31.9 Bipolar affective disorder, unspecified	0.699	0.301	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.698	0.302	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.698	0.302	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.698	0.302	0.000
T42.3 Barbiturates	0.698	0.302	0.000
T42.2 Succinimides and oxazolidinediones	0.698	0.302	0.000
T42.0 Hydantoin derivatives	0.698	0.302	0.000
S52.7 Multiple fractures of forearm	0.698	0.302	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.697	0.303	0.000
S02.5 Fracture of tooth	0.696	0.304	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.696	0.304	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.695	0.305	0.000
T40.4 Other synthetic narcotics	0.694	0.306	0.000
S06.2 Diffuse brain injury	0.694	0.306	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.693	0.306	0.000
S59 Other and unspecified injuries of forearm	0.693	0.307	0.000
F60-F69 Disorders of adult personality and behaviour	0.693	0.307	0.000
T18 Foreign body in alimentary tract	0.692	0.308	0.000
T43.9 Psychotropic drug, unspecified	0.692	0.308	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.692	0.308	0.000
T43.6 Psychostimulants with abuse potential	0.692	0.308	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.692	0.308	0.000
T51.0 Ethanol	0.691	0.309	0.000
S72.1 Pertrochanteric fracture	0.690	0.310	0.000
S90 Superficial injury of ankle and foot	0.684	0.316	0.000
S06.5 Traumatic subdural haemorrhage	0.683	0.317	0.000
F29 Unspecified nonorganic psychosis	0.683	0.317	0.000
S05.9 Injury of eye and orbit, part unspecified	0.679	0.321	0.000
S91.0 Open wound of ankle	0.678	0.322	0.000
S78 Traumatic amputation of hip and thigh	0.678	0.322	0.000
S77 Crushing injury of hip and thigh	0.678	0.322	0.000
S75 Injury of blood vessels at hip and thigh level	0.678	0.322	0.000
S74 Injury of nerves at hip and thigh level	0.678	0.322	0.000
S02.0 Fracture of vault of skull	0.677	0.323	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.676	0.324	0.000
T19 Foreign body in genito-urinary tract	0.676	0.324	0.000
T15 Foreign body on external eye	0.676	0.324	0.000
T16 Foreign body in ear	0.676	0.324	0.000
F60 Specific personality disorders	0.676	0.324	0.000
S99 Other and unspecified injuries of ankle and foot	0.674	0.326	0.000
S58 Traumatic amputation of forearm	0.673	0.327	0.000
S57 Crushing injury of forearm	0.673	0.327	0.000
S55 Injury of blood vessels at forearm level	0.673	0.327	0.000
S54 Injury of nerves at forearm level	0.673	0.327	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.673	0.327	0.000
S98 Traumatic amputation of ankle and foot	0.672	0.328	0.000
S97 Crushing injury of ankle and foot	0.672	0.328	0.000
S95 Injury of blood vessels at ankle and foot level	0.672	0.328	0.000
S94 Injury of nerves at ankle and foot level	0.672	0.328	0.000
T40.2 Other opioids	0.671	0.329	0.000
T23 Burn and corrosion of wrist and hand	0.670	0.330	0.000
T50.8 Diagnostic agents	0.669	0.331	0.000
T50.7 Analeptics and opioid receptor antagonists	0.669	0.331	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.669	0.331	0.000
T50.5 Appetite depressants	0.669	0.331	0.000
T50.4 Drugs affecting uric acid metabolism	0.669	0.331	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.669	0.331	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.669	0.331	0.000
T50.1 Loop [high-ceiling] diuretics	0.669	0.331	0.000
T50.0 Mineralocorticoids and their antagonists	0.669	0.331	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.666	0.334	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.663	0.337	0.000
S42.2 Fracture of upper end of humerus	0.662	0.337	0.000
S06.8 Other intracranial injuries	0.659	0.340	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.659	0.341	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.657	0.343	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.657	0.343	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.657	0.343	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.657	0.343	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.657	0.343	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.657	0.343	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.657	0.343	0.000
T44.0 Anticholinesterase agents	0.657	0.343	0.000
T45.5 Anticoagulants	0.655	0.345	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.650	0.350	0.000
S79 Other and unspecified injuries of hip and thigh	0.649	0.351	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.649	0.351	0.000
S42.4 Fracture of lower end of humerus	0.648	0.352	0.000
S80-S89 Injuries to the knee and lower leg	0.648	0.352	0.000
S06.9 Intracranial injury, unspecified	0.646	0.354	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.646	0.354	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.646	0.354	0.000
T46.7 Peripheral vasodilators	0.646	0.354	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.646	0.354	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.646	0.354	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.646	0.354	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.646	0.354	0.000
S72.2 Subtrochanteric fracture	0.645	0.354	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.645	0.355	0.000
T17.5 Foreign body in bronchus	0.645	0.355	0.000
T17.4 Foreign body in trachea	0.645	0.355	0.000
T17.3 Foreign body in larynx	0.645	0.355	0.000
T17.1 Foreign body in nostril	0.645	0.355	0.000
T17.0 Foreign body in nasal sinus	0.645	0.355	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.644	0.356	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.644	0.356	0.000
T66-T78 Other and unspecified effects of external causes	0.643	0.357	0.000
S06.7 Intracranial injury with prolonged coma	0.643	0.357	0.000
S06.1 Traumatic cerebral oedema	0.643	0.357	0.000
T65 Toxic effect of other and unspecified substances	0.636	0.364	0.000
T62 Toxic effect of other noxious substances eaten as food	0.636	0.364	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.636	0.364	0.000
T60 Toxic effect of pesticides	0.636	0.364	0.000
T57 Toxic effect of other inorganic substances	0.636	0.364	0.000
T54 Toxic effect of corrosive substances	0.636	0.364	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.636	0.364	0.000
T52 Toxic effect of organic solvents	0.636	0.364	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.636	0.364	0.000
T58 Toxic effect of carbon monoxide	0.636	0.364	0.000
T55 Toxic effect of soaps and detergents	0.636	0.364	0.000
S02.20 Fracture of nasal bones (closed)	0.629	0.371	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.629	0.371	0.000
S92.2 Fracture of other tarsal bone(s)	0.629	0.371	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.627	0.373	0.000
T40.8 Lysergide [LSD]	0.627	0.373	0.000
T40.7 Cannabis (derivatives)	0.627	0.373	0.000
T40.5 Cocaine	0.627	0.373	0.000
T40.3 Methadone	0.627	0.373	0.000
T40.1 Heroin	0.627	0.373	0.000
T40.0 Opium	0.627	0.373	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.627	0.373	0.000
S50.0 Contusion of elbow	0.627	0.373	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.625	0.375	0.000
S72.9 Fracture of femur, part unspecified	0.624	0.376	0.000
S72.8 Fractures of other parts of femur	0.624	0.376	0.000
S72.7 Multiple fractures of femur	0.624	0.376	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.624	0.376	0.000
T20 Burn and corrosion of head and neck	0.622	0.378	0.000
S06.0 Concussion	0.621	0.379	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.619	0.381	0.000
S92.1 Fracture of talus	0.618	0.382	0.000
S91.7 Multiple open wounds of ankle and foot	0.616	0.384	0.000
S91.2 Open wound of toe(s) with damage to nail	0.616	0.384	0.000
S91.1 Open wound of toe(s) without damage to nail	0.616	0.384	0.000
S92.30 Fracture of metatarsal bone (closed)	0.615	0.385	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.615	0.385	0.000
T45.8 Other primarily systemic and haematological agents	0.615	0.385	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.615	0.385	0.000
T45.6 Fibrinolysis-affecting drugs	0.615	0.385	0.000
T45.4 Iron and its compounds	0.615	0.385	0.000
T45.3 Enzymes, not elsewhere classified	0.615	0.385	0.000
T45.2 Vitamins, not elsewhere classified	0.615	0.385	0.000
S52.70 Multiple fractures of forearm (closed)	0.614	0.386	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.613	0.387	0.000
T21 Burn and corrosion of trunk	0.612	0.388	0.000
F80-F89 Disorders of psychological development	0.611	0.389	0.000
S09.8 Other specified injuries of head	0.610	0.390	0.000
S72.4 Fracture of lower end of femur	0.609	0.391	0.000
T79-T79 Certain early complications of trauma	0.609	0.391	0.000
S20-S29 Injuries to the thorax	0.609	0.391	0.000
F60.3 Emotionally unstable personality disorder	0.606	0.394	0.000
S41 Open wound of shoulder and upper arm	0.606	0.394	0.000
S06.3 Focal brain injury	0.605	0.395	0.000
S51 Open wound of forearm	0.605	0.395	0.000
T36.0 Penicillins	0.604	0.396	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.603	0.397	0.000
S50.8 Other superficial injuries of forearm	0.601	0.399	0.000
S02.11 Fracture of base of skull (open)	0.601	0.399	0.000
S48 Traumatic amputation of shoulder and upper arm	0.600	0.400	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.600	0.400	0.000
S44 Injury of nerves at shoulder and upper arm level	0.600	0.400	0.000
S47 Crushing injury of shoulder and upper arm	0.600	0.400	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.600	0.400	0.000
S42.20 Fracture of upper end of humerus (closed)	0.599	0.401	0.000
T25 Burn and corrosion of ankle and foot	0.598	0.402	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.595	0.405	0.000
S50.7 Multiple superficial injuries of forearm	0.595	0.405	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.595	0.405	0.000
S70.0 Contusion of hip	0.594	0.406	0.000
S92.5 Fracture of other toe	0.594	0.406	0.000
F60.9 Personality disorder, unspecified	0.593	0.407	0.000
S02.31 Fracture of orbital floor (open)	0.592	0.408	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.591	0.409	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.591	0.409	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.589	0.411	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.589	0.411	0.000
S02.81 Fractures of other skull and facial bones (open)	0.588	0.411	0.000
S92.9 Fracture of foot, unspecified	0.588	0.412	0.000
S92.7 Multiple fractures of foot	0.588	0.412	0.000
S92.4 Fracture of great toe	0.588	0.412	0.000
S05.1 Contusion of eyeball and orbital tissues	0.587	0.413	0.000
T51.8 Other alcohols	0.587	0.413	0.000
T51.3 Fusel oil	0.587	0.413	0.000
T51.2 2-Propanol	0.587	0.413	0.000
T51.1 Methanol	0.587	0.413	0.000
S52.8 Fracture of other parts of forearm	0.586	0.414	0.000
S52.9 Fracture of forearm, part unspecified	0.585	0.415	0.000
S52.4 Fracture of shafts of both ulna and radius	0.585	0.415	0.000
S52.3 Fracture of shaft of radius	0.585	0.415	0.000
S10-S19 Injuries to the neck	0.584	0.416	0.001
S72.01 Fracture of neck of femur (open)	0.583	0.417	0.000
S92.0 Fracture of calcaneus	0.582	0.417	0.000
F30 Manic episode	0.582	0.418	0.000
S42.3 Fracture of shaft of humerus	0.581	0.419	0.000
T00 Superficial injuries involving multiple body regions	0.580	0.419	0.000
T63 Toxic effect of contact with venomous animals	0.580	0.420	0.000
T56.8 Other metals	0.578	0.422	0.000
S71.1 Open wound of thigh	0.576	0.423	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.573	0.427	0.000
T38.1 Thyroid hormones and substitutes	0.572	0.428	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.571	0.429	0.000
T37.5 Antiviral drugs	0.571	0.429	0.000
T37.4 Anthelminthics	0.571	0.429	0.000
T37.3 Other antiprotozoal drugs	0.571	0.429	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.571	0.429	0.000
T37.1 Antimycobacterial drugs	0.571	0.429	0.000
T37.0 Sulphonamides	0.571	0.429	0.000
T23.2 Burn of second degree of wrist and hand	0.569	0.431	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.569	0.431	0.000
F20 Schizophrenia	0.568	0.432	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.567	0.433	0.000
S52.2 Fracture of shaft of ulna	0.566	0.433	0.000
F69 Unspecified disorder of adult personality and behaviour	0.566	0.434	0.000
F60.0 Paranoid personality disorder	0.562	0.438	0.000
S70.8 Other superficial injuries of hip and thigh	0.561	0.439	0.000
S02.21 Fracture of nasal bones (open)	0.560	0.439	0.000
S72.10 Pertrochanteric fracture (closed)	0.560	0.440	0.000
S02.60 Fracture of mandible (closed)	0.560	0.440	0.000
S05.7 Avulsion of eye	0.557	0.443	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.557	0.443	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.557	0.443	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.557	0.443	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.557	0.443	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.557	0.443	0.000
T11 Other injuries of upper limb, level unspecified	0.556	0.444	0.000
T31 Burns classified according to extent of body surface involved	0.553	0.447	0.000
F70-F79 Mental retardation	0.553	0.447	0.000
T36.9 Systemic antibiotic, unspecified	0.551	0.448	0.000
T36.8 Other systemic antibiotics	0.551	0.448	0.000
T36.7 Antifungal antibiotics, systemically used	0.551	0.448	0.000
T36.6 Rifamycins	0.551	0.448	0.000
T36.5 Aminoglycosides	0.551	0.448	0.000
T36.4 Tetracyclines	0.551	0.448	0.000
T36.3 Macrolides	0.551	0.448	0.000
T36.2 Chloramphenicol group	0.551	0.448	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.551	0.448	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.549	0.451	0.000
S42.40 Fracture of lower end of humerus (closed)	0.548	0.452	0.000
F60.6 Anxious [avoidant] personality disorder	0.546	0.454	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.546	0.454	0.000
S20 Superficial injury of thorax	0.546	0.454	0.000
T59 Toxic effect of other gases, fumes and vapours	0.546	0.454	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.545	0.455	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.545	0.455	0.000
T47.7 Emetics	0.545	0.455	0.000
T47.6 Antidiarrhoeal drugs	0.545	0.455	0.000
T47.5 Digestants	0.545	0.455	0.000
T47.4 Other laxatives	0.545	0.455	0.000
T47.3 Saline and osmotic laxatives	0.545	0.455	0.000
T47.2 Stimulant laxatives	0.545	0.455	0.000
T47.0 Histamine H(2)-receptor antagonists	0.545	0.455	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.544	0.456	0.000
S81 Open wound of lower leg	0.544	0.456	0.000
S72.3 Fracture of shaft of femur	0.543	0.457	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.542	0.458	0.000
T05 Traumatic amputations involving multiple body regions	0.542	0.458	0.000
T04 Crushing injuries involving multiple body regions	0.542	0.458	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.542	0.458	0.000
T02 Fractures involving multiple body regions	0.542	0.458	0.000
T01 Open wounds involving multiple body regions	0.542	0.458	0.000
T07 Unspecified multiple injuries	0.542	0.458	0.000
F01 Vascular dementia	0.541	0.459	0.000
F81 Specific developmental disorders of scholastic skills	0.540	0.460	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.539	0.461	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.539	0.461	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.536	0.464	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.536	0.464	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.535	0.465	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.533	0.467	0.000
T18.1 Foreign body in oesophagus	0.532	0.468	0.000
S02.61 Fracture of mandible (open)	0.532	0.468	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.530	0.470	0.000
T32 Corrosions classified according to extent of body surface involved	0.530	0.470	0.000
T30 Burn and corrosion, body region unspecified	0.530	0.470	0.000
T29 Burns and corrosions of multiple body regions	0.530	0.470	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.530	0.470	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.530	0.470	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.530	0.470	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.530	0.470	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.530	0.470	0.000
T38.9 Other and unspecified hormone antagonists	0.529	0.470	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.529	0.470	0.000
T38.7 Androgens and anabolic congeners	0.529	0.470	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.529	0.470	0.000
T38.5 Other oestrogens and progestogens	0.529	0.470	0.000
T38.4 Oral contraceptives	0.529	0.470	0.000
T38.2 Antithyroid drugs	0.529	0.470	0.000
T38.0 Glucocorticoids and synthetic analogues	0.529	0.470	0.000
S76.1 Injury of quadriceps muscle and tendon	0.529	0.471	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.529	0.471	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.529	0.471	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.529	0.471	0.000
S76.0 Injury of muscle and tendon of hip	0.529	0.471	0.000
S52.51 Fracture of lower end of radius (open)	0.527	0.473	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.525	0.475	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.525	0.475	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.524	0.476	0.000
S71.7 Multiple open wounds of of hip and thigh	0.524	0.476	0.000
S71.0 Open wound of hip	0.524	0.476	0.000
T39.0 Salicylates	0.520	0.480	0.000
S59.9 Unspecified injury of forearm	0.518	0.482	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.517	0.483	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.517	0.483	0.000
T39.4 Antirheumatics, not elsewhere classified	0.517	0.483	0.000
T39.2 Pyrazolone derivatives	0.517	0.483	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.516	0.484	0.000
S40 Superficial injury of shoulder and upper arm	0.516	0.484	0.000
F17.2 Dependence syndrome	0.515	0.485	0.000
T41.5 Therapeutic gases	0.514	0.486	0.000
T41.4 Anaesthetic, unspecified	0.514	0.486	0.000
T41.3 Local anaesthetics	0.514	0.486	0.000
T41.2 Other and unspecified general anaesthetics	0.514	0.486	0.000
T41.1 Intravenous anaesthetics	0.514	0.486	0.000
T41.0 Inhaled anaesthetics	0.514	0.486	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.514	0.486	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.514	0.486	0.000
T48.5 Anti-common-cold drugs	0.514	0.486	0.000
T48.4 Expectorants	0.514	0.486	0.000
T48.3 Antitussives	0.514	0.486	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.514	0.486	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.514	0.486	0.000
T48.0 Oxytocic drugs	0.514	0.486	0.000
T49.9 Topical agent, unspecified	0.514	0.486	0.000
T49.8 Other topical agents	0.514	0.486	0.000
T49.7 Dental drugs, topically applied	0.514	0.486	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.514	0.486	0.000
T49.5 Ophthalmological drugs and preparations	0.514	0.486	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.514	0.486	0.000
T49.3 Emollients, demulcents and protectants	0.514	0.486	0.000
T49.2 Local astringents and local detergents	0.514	0.486	0.000
T49.1 Antipruritics	0.514	0.486	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.514	0.486	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.514	0.486	0.000
T28 Burn and corrosion of other internal organs	0.514	0.486	0.000
T27 Burn and corrosion of respiratory tract	0.514	0.486	0.000
T26 Burn and corrosion confined to eye and adnexa	0.514	0.486	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.514	0.486	0.000
T34 Frostbite with tissue necrosis	0.514	0.486	0.000
T33 Superficial frostbite	0.514	0.486	0.000
F25 Schizoaffective disorders	0.514	0.486	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.514	0.486	0.000
S03.4 Sprain and strain of jaw	0.514	0.486	0.000
S03.3 Dislocation of other and unspecified parts of head	0.514	0.486	0.000
S03.2 Dislocation of tooth	0.514	0.486	0.000
S03.1 Dislocation of septal cartilage of nose	0.514	0.486	0.000
S03.0 Dislocation of jaw	0.514	0.486	0.000
S04.9 Injury of unspecified cranial nerve	0.514	0.486	0.000
S04.8 Injury of other cranial nerves	0.514	0.486	0.000
S04.7 Injury of accessory nerve	0.514	0.486	0.000
S04.6 Injury of acoustic nerve	0.514	0.486	0.000
S04.5 Injury of facial nerve	0.514	0.486	0.000
S04.4 Injury of abducent nerve	0.514	0.486	0.000
S04.3 Injury of trigeminal nerve	0.514	0.486	0.000
S04.2 Injury of trochlear nerve	0.514	0.486	0.000
S04.1 Injury of oculomotor nerve	0.514	0.486	0.000
S04.0 Injury of optic nerve and pathways	0.514	0.486	0.000
S07.9 Crushing injury of head, part unspecified	0.514	0.486	0.000
S07.8 Crushing injury of other parts of head	0.514	0.486	0.000
S07.1 Crushing injury of skull	0.514	0.486	0.000
S07.0 Crushing injury of face	0.514	0.486	0.000
S08.9 Traumatic amputation of unspecified part of head	0.514	0.486	0.000
S08.8 Traumatic amputation of other parts of head	0.514	0.486	0.000
S08.1 Traumatic amputation of ear	0.514	0.486	0.000
S08.0 Avulsion of scalp	0.514	0.486	0.000
S42.41 Fracture of lower end of humerus (open)	0.513	0.487	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.513	0.487	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.511	0.488	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.511	0.488	0.000
S05.8 Other injuries of eye and orbit	0.509	0.491	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.507	0.493	0.000
T56.9 Metal, unspecified	0.507	0.493	0.000
T56.7 Beryllium and its compounds	0.507	0.493	0.000
T56.6 Tin and its compounds	0.507	0.493	0.000
T56.5 Zinc and its compounds	0.507	0.493	0.000
T56.4 Copper and its compounds	0.507	0.493	0.000
T56.3 Cadmium and its compounds	0.507	0.493	0.000
T56.2 Chromium and its compounds	0.507	0.493	0.000
T56.1 Mercury and its compounds	0.507	0.493	0.000
T56.0 Lead and its compounds	0.507	0.493	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.504	0.496	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.503	0.497	0.000
S42.0 Fracture of clavicle	0.503	0.497	0.000
S92.31 Fracture of metatarsal bone (open)	0.502	0.498	0.000
T13 Other injuries of lower limb, level unspecified	0.502	0.498	0.000
T09 Other injuries of spine and trunk, level unspecified	0.502	0.498	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.502	0.498	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.502	0.498	0.000
T12 Fracture of lower limb, level unspecified	0.502	0.498	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.502	0.498	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.502	0.498	0.000
T10 Fracture of upper limb, level unspecified	0.502	0.498	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.502	0.498	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.502	0.498	0.000
T08 Fracture of spine, level unspecified	0.502	0.498	0.000
F38 Other mood [affective] disorders	0.502	0.498	0.000
F31.8 Other bipolar affective disorders	0.501	0.499	0.000
F31.7 Bipolar affective disorder, currently in remission	0.501	0.499	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.501	0.499	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.501	0.499	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.501	0.499	0.000
S52.71 Multiple fractures of forearm (open)	0.500	0.499	0.000
F32 Depressive episode	0.500	0.500	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.500	0.500	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.500	0.500	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.500	0.500	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations