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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13190943
log Bayes Factor = 5.39281
Chromosome 6   position 37,414,355  (GRCh37) Explore rs13190943 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
E10-E14 Diabetes mellitus
0.989 0.011 0.000
F30-F39 Mood [affective] disorders
0.988 0.012 0.000
E11 Non-insulin-dependent diabetes mellitus
0.981 0.019 0.000
G90-G99 Other disorders of the nervous system
0.976 0.024 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.971 0.029 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.969 0.031 0.000
Chapter I Certain infectious and parasitic diseases
0.969 0.031 0.000
H65-H75 Diseases of middle ear and mastoid
0.966 0.034 0.000
H80-H83 Diseases of inner ear
0.965 0.035 0.000
F60-F69 Disorders of adult personality and behaviour
0.961 0.039 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.961 0.039 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.960 0.040 0.000
H90-H95 Other disorders of ear
0.960 0.040 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.958 0.042 0.000
E10 Insulin-dependent diabetes mellitus
0.951 0.049 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.949 0.051 0.000
F31 Bipolar affective disorder
0.947 0.053 0.000
F60 Specific personality disorders
0.933 0.067 0.000
H81 Disorders of vestibular function
0.933 0.067 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.933 0.067 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.932 0.068 0.000
E20-E35 Disorders of other endocrine glands
0.932 0.068 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.930 0.070 0.000
B25-B34 Other viral diseases
0.925 0.075 0.000
H90 Conductive and sensorineural hearing loss
0.925 0.075 0.000
F33 Recurrent depressive disorder
0.924 0.076 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.923 0.077 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.915 0.085 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.912 0.088 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.910 0.090 0.000
H81.0 Meniere's disease
0.909 0.091 0.000
E11.3 With ophthalmic complications
0.906 0.094 0.000
H65 Nonsuppurative otitis media
0.901 0.099 0.000
E11.9 Without complications
0.897 0.103 0.000
B34 Viral infection of unspecified site
0.897 0.103 0.000
F60.3 Emotionally unstable personality disorder
0.892 0.108 0.000
D80-D89 Certain disorders involving the immune mechanism
0.890 0.110 0.000
E11.4 With neurological complications
0.890 0.110 0.000
Q60-Q64 Congenital malformations of the urinary system
0.884 0.116 0.000
F03 Unspecified dementia
0.882 0.118 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.877 0.123 0.000
G62 Other polyneuropathies
0.875 0.125 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.872 0.128 0.000
T66-T78 Other and unspecified effects of external causes
0.869 0.131 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.869 0.131 0.000
E10.3 With ophthalmic complications
0.868 0.132 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.868 0.132 0.000
A30-A49 Other bacterial diseases
0.866 0.134 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.866 0.134 0.000
H74 Other disorders of middle ear and mastoid
0.865 0.135 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.859 0.141 0.000
B34.9 Viral infection, unspecified
0.858 0.142 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.856 0.144 0.000
G20-G26 Extrapyramidal and movement disorders
0.855 0.145 0.000
S50-S59 Injuries to the elbow and forearm
0.855 0.145 0.000
D50-D53 Nutritional anaemias
0.847 0.153 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.847 0.153 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.844 0.156 0.000
T51 Toxic effect of alcohol
0.840 0.160 0.000
H90.2 Conductive hearing loss, unspecified
0.839 0.161 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.838 0.162 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.834 0.166 0.000
B35-B49 Mycoses
0.831 0.169 0.000
S70-S79 Injuries to the hip and thigh
0.830 0.170 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.830 0.170 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.830 0.170 0.000
T81 Complications of procedures, not elsewhere classified
0.827 0.173 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.826 0.174 0.000
E28 Ovarian dysfunction
0.825 0.175 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.825 0.175 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.819 0.181 0.000
Q24 Other congenital malformations of heart
0.819 0.181 0.000
G62.9 Polyneuropathy, unspecified
0.816 0.184 0.000
S90-S99 Injuries to the ankle and foot
0.812 0.188 0.000
F60.9 Personality disorder, unspecified
0.807 0.193 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.804 0.196 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.802 0.198 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.801 0.199 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.801 0.199 0.000
T51.9 Alcohol, unspecified
0.801 0.199 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.800 0.200 0.000
Q27 Other congenital malformations of peripheral vascular system
0.798 0.202 0.000
T87 Complications peculiar to reattachment and amputation
0.797 0.203 0.000
T93 Sequelae of injuries of lower limb
0.796 0.204 0.000
F39 Unspecified mood [affective] disorder
0.795 0.205 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.793 0.207 0.000
D55-D59 Haemolytic anaemias
0.789 0.211 0.000
H65.4 Other chronic nonsuppurative otitis media
0.787 0.213 0.000
G63.2 Diabetic polyneuropathy
0.787 0.213 0.000
Q28 Other congenital malformations of circulatory system
0.787 0.213 0.000
E10.4 With neurological complications
0.784 0.216 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.784 0.216 0.000
S10-S19 Injuries to the neck
0.784 0.216 0.000
E22 Hyperfunction of pituitary gland
0.783 0.217 0.000
G70-G73 Diseases of myoneural junction and muscle
0.783 0.217 0.000
E11.6 With other specified complications
0.782 0.218 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.781 0.219 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.781 0.219 0.000
T78 Adverse effects, not elsewhere classified
0.781 0.219 0.000
E27 Other disorders of adrenal gland
0.781 0.219 0.000
E14 Unspecified diabetes mellitus
0.780 0.220 0.000
A40 Streptococcal septicaemia
0.779 0.221 0.000
Q21 Congenital malformations of cardiac septa
0.778 0.222 0.000
G95 Other diseases of spinal cord
0.774 0.226 0.000
B07 Viral warts
0.773 0.227 0.000
H80 Otosclerosis
0.771 0.229 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.771 0.229 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.771 0.229 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.770 0.230 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.766 0.233 0.000
T00-T07 Injuries involving multiple body regions
0.765 0.235 0.000
G24 Dystonia
0.764 0.236 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.764 0.236 0.000
B34.8 Other viral infections of unspecified site
0.761 0.238 0.000
Q80-Q89 Other congenital malformations
0.761 0.239 0.000
S30.0 Contusion of lower back and pelvis
0.759 0.241 0.000
F01 Vascular dementia
0.759 0.241 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.759 0.241 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.757 0.243 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.754 0.246 0.000
A80-A89 Viral infections of the central nervous system
0.754 0.246 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.754 0.246 0.000
H72 Perforation of tympanic membrane
0.753 0.247 0.000
H90.0 Conductive hearing loss, bilateral
0.751 0.249 0.000
F80-F89 Disorders of psychological development
0.751 0.249 0.000
A41 Other septicaemia
0.751 0.249 0.000
E11.2 With renal complications
0.750 0.250 0.000
G61 Inflammatory polyneuropathy
0.750 0.250 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.749 0.251 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.748 0.252 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.744 0.256 0.000
H81.1 Benign paroxysmal vertigo
0.744 0.256 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.742 0.258 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.741 0.259 0.000
S30.1 Contusion of abdominal wall
0.741 0.259 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.740 0.260 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.739 0.261 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.739 0.261 0.000
E11.1 With ketoacidosis
0.737 0.262 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.736 0.263 0.000
E28.2 Polycystic ovarian syndrome
0.736 0.264 0.000
F00 Dementia in Alzheimer's disease
0.736 0.264 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.736 0.264 0.000
D70 Agranulocytosis
0.735 0.265 0.000
E10.1 With ketoacidosis
0.734 0.266 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.733 0.267 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.733 0.267 0.000
T78.3 Angioneurotic oedema
0.731 0.269 0.000
D72 Other disorders of white blood cells
0.726 0.274 0.000
E10.5 With peripheral circulatory complications
0.726 0.274 0.000
E50-E64 Other nutritional deficiencies
0.725 0.275 0.000
T63 Toxic effect of contact with venomous animals
0.724 0.276 0.000
H66 Suppurative and unspecified otitis media
0.724 0.276 0.000
H91 Other hearing loss
0.724 0.276 0.000
H69 Other disorders of Eustachian tube
0.723 0.277 0.000
H70 Mastoiditis and related conditions
0.722 0.277 0.000
T81.9 Unspecified complication of procedure
0.721 0.279 0.000
H93 Other disorders of ear, not elsewhere classified
0.721 0.279 0.000
D52 Folate deficiency anaemia
0.721 0.279 0.000
E10.0 With coma
0.720 0.280 0.000
E14.3 With ophthalmic complications
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F31.9 Bipolar affective disorder, unspecified
0.717 0.283 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.717 0.283 0.000
G96 Other disorders of central nervous system
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.283 0.000
F70-F79 Mental retardation
0.716 0.283 0.000
H90.3 Sensorineural hearing loss, bilateral
0.716 0.284 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
H65.3 Chronic mucoid otitis media
0.714 0.286 0.000
G91 Hydrocephalus
0.714 0.286 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.713 0.287 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.713 0.287 0.000
Q35-Q37 Cleft lip and cleft palate
0.712 0.288 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.712 0.288 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.710 0.290 0.000
F02 Dementia in other diseases classified elsewhere
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.709 0.291 0.000
Q63 Other congenital malformations of kidney
0.708 0.291 0.000
F38 Other mood [affective] disorders
0.708 0.292 0.000
F34 Persistent mood [affective] disorders
0.708 0.292 0.000
F33.9 Recurrent depressive disorder, unspecified
0.708 0.292 0.000
S56 Injury of muscle and tendon at forearm level
0.708 0.292 0.000
G00 Bacterial meningitis, not elsewhere classified
0.708 0.292 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.707 0.293 0.000
Chapter XXII Codes for special purposes
0.706 0.294 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.706 0.294 0.000
T40.2 Other opioids
0.705 0.295 0.000
E11.7 With multiple complications
0.703 0.297 0.000
E11.0 With coma
0.703 0.297 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.702 0.298 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.700 0.300 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.700 0.300 0.000
G92 Toxic encephalopathy
0.700 0.300 0.000
E10.2 With renal complications
0.699 0.301 0.000
S70 Superficial injury of hip and thigh
0.699 0.301 0.000
B35 Dermatophytosis
0.698 0.302 0.000
T91 Sequelae of injuries of neck and trunk
0.698 0.302 0.000
H81.9 Disorder of vestibular function, unspecified
0.697 0.303 0.000
B37 Candidiasis
0.696 0.304 0.000
T87.3 Neuroma of amputation stump
0.695 0.305 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.695 0.305 0.000
D73 Diseases of spleen
0.695 0.305 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.694 0.305 0.000
B50-B64 Protozoal diseases
0.694 0.305 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.694 0.305 0.000
A75-A79 Rickettsioses
0.694 0.305 0.000
A70-A74 Other diseases caused by chlamydiae
0.694 0.305 0.000
A65-A69 Other spirochaetal diseases
0.694 0.305 0.000
A20-A28 Certain zoonotic bacterial diseases
0.694 0.305 0.000
A15-A19 Tuberculosis
0.694 0.305 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.694 0.306 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.693 0.307 0.000
H68 Eustachian salpingitis and obstruction
0.693 0.307 0.000
H67 Otitis media in diseases classified elsewhere
0.693 0.307 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.692 0.308 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.691 0.309 0.000
Q27.3 Peripheral arteriovenous malformation
0.689 0.311 0.000
H74.4 Polyp of middle ear
0.689 0.311 0.000
T93.2 Sequelae of other fractures of lower limb
0.689 0.311 0.000
F68 Other disorders of adult personality and behaviour
0.689 0.311 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.689 0.311 0.000
F65 Disorders of sexual preference
0.689 0.311 0.000
F64 Gender identity disorders
0.689 0.311 0.000
F63 Habit and impulse disorders
0.689 0.311 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.689 0.311 0.000
F69 Unspecified disorder of adult personality and behaviour
0.689 0.311 0.000
F61 Mixed and other personality disorders
0.689 0.311 0.000
G64 Other disorders of peripheral nervous system
0.689 0.311 0.000
Q60.0 Renal agenesis, unilateral
0.689 0.311 0.000
Q78 Other osteochondrodysplasias
0.688 0.312 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.688 0.312 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.688 0.312 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.688 0.312 0.000
B27 Infectious mononucleosis
0.688 0.312 0.000
F09 Unspecified organic or symptomatic mental disorder
0.687 0.313 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.687 0.313 0.000
H65.2 Chronic serous otitis media
0.686 0.314 0.000
F30 Manic episode
0.685 0.314 0.000
G60 Hereditary and idiopathic neuropathy
0.684 0.316 0.000
E10.9 Without complications
0.683 0.317 0.000
Q50-Q56 Congenital malformations of genital organs
0.682 0.318 0.000
E10.8 With unspecified complications
0.681 0.318 0.000
E10.7 With multiple complications
0.681 0.318 0.000
E10.6 With other specified complications
0.681 0.318 0.000
Q26 Congenital malformations of great veins
0.680 0.320 0.000
Q25 Congenital malformations of great arteries
0.680 0.320 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.680 0.320 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.680 0.320 0.000
Q00-Q07 Congenital malformations of the nervous system
0.680 0.320 0.000
H74.1 Adhesive middle ear disease
0.680 0.320 0.000
B02 Zoster [herpes zoster]
0.679 0.321 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.679 0.321 0.000
F31.8 Other bipolar affective disorders
0.679 0.321 0.000
F31.7 Bipolar affective disorder, currently in remission
0.679 0.321 0.000
E11.8 With unspecified complications
0.678 0.322 0.000
Q21.0 Ventricular septal defect
0.678 0.322 0.000
F45 Somatoform disorders
0.678 0.322 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.675 0.324 0.000
E22.1 Hyperprolactinaemia
0.675 0.325 0.000
H83 Other diseases of inner ear
0.675 0.325 0.000
D51 Vitamin B12 deficiency anaemia
0.675 0.325 0.000
S52 Fracture of forearm
0.674 0.326 0.000
Q66 Congenital deformities of feet
0.673 0.326 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.673 0.327 0.000
S32 Fracture of lumbar spine and pelvis
0.671 0.329 0.000
B99-B99 Other infectious diseases
0.671 0.329 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.671 0.329 0.000
F60.8 Other specific personality disorders
0.669 0.331 0.000
F60.7 Dependent personality disorder
0.669 0.331 0.000
F60.6 Anxious [avoidant] personality disorder
0.669 0.331 0.000
F60.5 Anankastic personality disorder
0.669 0.331 0.000
F60.4 Histrionic personality disorder
0.669 0.331 0.000
F60.2 Dissocial personality disorder
0.669 0.331 0.000
F60.1 Schizoid personality disorder
0.669 0.331 0.000
F60.0 Paranoid personality disorder
0.669 0.331 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.669 0.331 0.000
T36 Poisoning by systemic antibiotics
0.669 0.331 0.000
H81.8 Other disorders of vestibular function
0.669 0.331 0.000
H81.4 Vertigo of central origin
0.669 0.331 0.000
H81.3 Other peripheral vertigo
0.669 0.331 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.669 0.331 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.669 0.331 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.669 0.331 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.669 0.331 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.668 0.332 0.000
E32 Diseases of thymus
0.668 0.332 0.000
E31 Polyglandular dysfunction
0.668 0.332 0.000
E30 Disorders of puberty, not elsewhere classified
0.668 0.332 0.000
E26 Hyperaldosteronism
0.668 0.332 0.000
E25 Adrenogenital disorders
0.668 0.332 0.000
E24 Cushing's syndrome
0.668 0.332 0.000
E20 Hypoparathyroidism
0.668 0.332 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.668 0.332 0.000
B65-B83 Helminthiases
0.667 0.332 0.000
Chapter XX External causes of morbidity and mortality
0.667 0.333 0.000
T83.2 Mechanical complication of graft of urinary organ
0.667 0.333 0.000
H73 Other disorders of tympanic membrane
0.667 0.333 0.000
F32 Depressive episode
0.666 0.334 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.666 0.334 0.000
S40-S49 Injuries to the shoulder and upper arm
0.666 0.334 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.665 0.334 0.000
G24.9 Dystonia, unspecified
0.665 0.334 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.664 0.336 0.000
B33 Other viral diseases, not elsewhere classified
0.663 0.337 0.000
B30 Viral conjunctivitis
0.663 0.337 0.000
B26 Mumps
0.663 0.337 0.000
B15-B19 Viral hepatitis
0.663 0.337 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.663 0.337 0.000
F33.8 Other recurrent depressive disorders
0.662 0.337 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.662 0.337 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.662 0.337 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.662 0.338 0.000
S37 Injury of urinary and pelvic organs
0.662 0.338 0.000
S36 Injury of intra-abdominal organs
0.662 0.338 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.662 0.338 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.662 0.338 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.662 0.338 0.000
S31 Open wound of abdomen, lower back and pelvis
0.662 0.338 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.661 0.339 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.661 0.339 0.000
D59 Acquired haemolytic anaemia
0.660 0.340 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.659 0.341 0.000
T65 Toxic effect of other and unspecified substances
0.656 0.344 0.000
T62 Toxic effect of other noxious substances eaten as food
0.656 0.344 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.656 0.344 0.000
T60 Toxic effect of pesticides
0.656 0.344 0.000
T59 Toxic effect of other gases, fumes and vapours
0.656 0.344 0.000
T57 Toxic effect of other inorganic substances
0.656 0.344 0.000
T56 Toxic effect of metals
0.656 0.344 0.000
T54 Toxic effect of corrosive substances
0.656 0.344 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.656 0.344 0.000
T52 Toxic effect of organic solvents
0.656 0.344 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.656 0.344 0.000
T55 Toxic effect of soaps and detergents
0.656 0.344 0.000
D86 Sarcoidosis
0.656 0.344 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.655 0.344 0.000
G90 Disorders of autonomic nervous system
0.655 0.345 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.654 0.346 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.654 0.346 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.654 0.346 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.654 0.346 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.653 0.347 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.652 0.347 0.000
A41.9 Septicaemia, unspecified
0.652 0.348 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.651 0.349 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.651 0.349 0.000
T40.6 Other and unspecified narcotics
0.651 0.349 0.000
S51 Open wound of forearm
0.647 0.352 0.000
A48 Other bacterial diseases, not elsewhere classified
0.647 0.353 0.000
E65-E68 Obesity and other hyperalimentation
0.647 0.353 0.000
S91 Open wound of ankle and foot
0.646 0.354 0.000
H65.1 Other acute nonsuppurative otitis media
0.646 0.354 0.000
H65.0 Acute serous otitis media
0.646 0.354 0.000
Q23 Congenital malformations of aortic and mitral valves
0.646 0.354 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.645 0.355 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.645 0.355 0.000
E13 Other specified diabetes mellitus
0.644 0.356 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.644 0.356 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.643 0.357 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.643 0.357 0.000
B34.4 Papovirus infection, unspecified
0.643 0.357 0.000
B34.3 Parvovirus infection, unspecified
0.643 0.357 0.000
B34.2 Coronavirus infection, unspecified
0.643 0.357 0.000
B34.1 Enterovirus infection, unspecified
0.643 0.357 0.000
B34.0 Adenovirus infection, unspecified
0.643 0.357 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.641 0.359 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.640 0.360 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.639 0.361 0.000
S12 Fracture of neck
0.638 0.362 0.000
D84 Other immunodeficiencies
0.638 0.362 0.000
D83 Common variable immunodeficiency
0.638 0.362 0.000
D82 Immunodeficiency associated with other major defects
0.638 0.362 0.000
D81 Combined immunodeficiencies
0.638 0.362 0.000
G71 Primary disorders of muscles
0.638 0.362 0.000
D53 Other nutritional anaemias
0.638 0.362 0.000
Q61 Cystic kidney disease
0.638 0.362 0.000
T58 Toxic effect of carbon monoxide
0.637 0.363 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.637 0.363 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.636 0.364 0.000
F07.0 Organic personality disorder
0.636 0.364 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.634 0.366 0.000
Q64 Other congenital malformations of urinary system
0.634 0.366 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.634 0.366 0.000
Q24.8 Other specified congenital malformations of heart
0.634 0.366 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.634 0.366 0.000
G20 Parkinson's disease
0.633 0.367 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.633 0.367 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.633 0.367 0.000
H80.9 Otosclerosis, unspecified
0.632 0.368 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.632 0.368 0.000
D52.9 Folate deficiency anaemia, unspecified
0.631 0.369 0.000
E23 Hypofunction and other disorders of pituitary gland
0.630 0.370 0.000
A86 Unspecified viral encephalitis
0.630 0.370 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.629 0.371 0.000
S30.2 Contusion of external genital organs
0.629 0.371 0.000
E27.1 Primary adrenocortical insufficiency
0.629 0.371 0.000
H95.1 Other disorders following mastoidectomy
0.628 0.372 0.000
Q76 Congenital malformations of spine and bony thorax
0.628 0.372 0.000
F99-F99 Unspecified mental disorder
0.627 0.372 0.000
G62.2 Polyneuropathy due to other toxic agents
0.627 0.372 0.000
G62.1 Alcoholic polyneuropathy
0.627 0.372 0.000
G62.0 Drug-induced polyneuropathy
0.627 0.372 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.627 0.373 0.000
S90 Superficial injury of ankle and foot
0.626 0.373 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.626 0.374 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.626 0.374 0.000
E28.3 Primary ovarian failure
0.625 0.375 0.000
G11 Hereditary ataxia
0.624 0.376 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.624 0.376 0.000
B00 Herpesviral [herpes simplex] infections
0.624 0.376 0.000
T75 Effects of other external causes
0.623 0.377 0.000
T74 Maltreatment syndromes
0.623 0.377 0.000
T73 Effects of other deprivation
0.623 0.377 0.000
T70 Effects of air pressure and water pressure
0.623 0.377 0.000
T69 Other effects of reduced temperature
0.623 0.377 0.000
T67 Effects of heat and light
0.623 0.377 0.000
T71 Asphyxiation
0.623 0.377 0.000
T66 Unspecified effects of radiation
0.623 0.377 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.623 0.377 0.000
Q75 Other congenital malformations of skull and face bones
0.623 0.377 0.000
Q74 Other congenital malformations of limb(s)
0.623 0.377 0.000
Q73 Reduction defects of unspecified limb
0.623 0.377 0.000
Q72 Reduction defects of lower limb
0.623 0.377 0.000
Q71 Reduction defects of upper limb
0.623 0.377 0.000
Q70 Syndactyly
0.623 0.377 0.000
Q69 Polydactyly
0.623 0.377 0.000
Q68 Other congenital musculoskeletal deformities
0.623 0.377 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.623 0.377 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.623 0.377 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.622 0.378 0.000
B06 Rubella [German measles]
0.622 0.378 0.000
B05 Measles
0.622 0.378 0.000
B01 Varicella [chickenpox]
0.622 0.378 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.622 0.378 0.000
B04 Monkeypox
0.622 0.378 0.000
B03 Smallpox
0.622 0.378 0.000
A44 Bartonellosis
0.621 0.379 0.000
A43 Nocardiosis
0.621 0.379 0.000
A42 Actinomycosis
0.621 0.379 0.000
A39 Meningococcal infection
0.621 0.379 0.000
A37 Whooping cough
0.621 0.379 0.000
A36 Diphtheria
0.621 0.379 0.000
A32 Listeriosis
0.621 0.379 0.000
A31 Infection due to other mycobacteria
0.621 0.379 0.000
A30 Leprosy [Hansen's disease]
0.621 0.379 0.000
A38 Scarlet fever
0.621 0.379 0.000
A35 Other tetanus
0.621 0.379 0.000
A34 Obstetrical tetanus
0.621 0.379 0.000
A33 Tetanus neonatorum
0.621 0.379 0.000
G24.5 Blepharospasm
0.621 0.379 0.000
E34 Other endocrine disorders
0.621 0.379 0.000
T98 Sequelae of other and unspecified effects of external causes
0.621 0.379 0.000
T95 Sequelae of burns, corrosions and frostbite
0.621 0.379 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.621 0.379 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.621 0.379 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.620 0.380 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.620 0.380 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.620 0.380 0.000
Q65 Congenital deformities of hip
0.619 0.381 0.000
E11.5 With peripheral circulatory complications
0.619 0.381 0.000
A40.0 Septicaemia due to streptococcus, group A
0.618 0.382 0.000
G62.8 Other specified polyneuropathies
0.618 0.382 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.616 0.384 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.616 0.384 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.616 0.384 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.616 0.384 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.616 0.384 0.000
G63.1 Polyneuropathy in neoplastic disease
0.616 0.384 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.616 0.384 0.000
F01.9 Vascular dementia, unspecified
0.616 0.384 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.616 0.384 0.000
B44 Aspergillosis
0.615 0.385 0.000
G95.2 Cord compression, unspecified
0.615 0.385 0.000
H66.9 Otitis media, unspecified
0.615 0.385 0.000
D74 Methaemoglobinaemia
0.614 0.386 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.614 0.386 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.614 0.386 0.000
G23 Other degenerative diseases of basal ganglia
0.613 0.387 0.000
G21 Secondary Parkinsonism
0.613 0.387 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.613 0.387 0.000
G22 Parkinsonism in diseases classified elsewhere
0.613 0.387 0.000
S59 Other and unspecified injuries of forearm
0.613 0.387 0.000
S58 Traumatic amputation of forearm
0.613 0.387 0.000
S57 Crushing injury of forearm
0.613 0.387 0.000
S55 Injury of blood vessels at forearm level
0.613 0.387 0.000
S54 Injury of nerves at forearm level
0.613 0.387 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.613 0.387 0.000
T68 Hypothermia
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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