TreeWAS – Variant ID: rs13197574

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
N40 Hyperplasia of prostate	0.000	0.000	1.000
Chapter XI Diseases of the digestive system	0.987	0.000	0.013
E03 Other hypothyroidism	1.000	0.000	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.000	1.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.999	0.001	0.000
K40 Inguinal hernia	0.000	0.001	0.999
M35.0 Sicca syndrome [Sjogren]	0.999	0.001	0.000
K90-K93 Other diseases of the digestive system	0.986	0.001	0.013
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.001	0.999
Chapter XII Diseases of the skin and subcutaneous tissue	0.999	0.001	0.000
K90 Intestinal malabsorption	0.998	0.001	0.001
E20-E35 Disorders of other endocrine glands	0.999	0.001	0.000
E27 Other disorders of adrenal gland	0.998	0.002	0.000
K44 Diaphragmatic hernia	0.000	0.002	0.998
K40-K46 Hernia	0.000	0.002	0.997
E27.1 Primary adrenocortical insufficiency	0.998	0.002	0.000
D80-D89 Certain disorders involving the immune mechanism	0.995	0.005	0.000
M05-M14 Inflammatory polyarthropathies	0.995	0.005	0.000
H30-H36 Disorders of choroid and retina	0.994	0.006	0.000
E83.1 Disorders of iron metabolism	0.000	0.006	0.994
K70-K77 Diseases of liver	0.992	0.008	0.001
K75 Other inflammatory liver diseases	0.992	0.008	0.000
E10.3 With ophthalmic complications	0.992	0.008	0.000
M20.1 Hallux valgus (acquired)	0.000	0.010	0.990
K75.4 Autoimmune hepatitis	0.990	0.010	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.990	0.010	0.000
E11 Non-insulin-dependent diabetes mellitus	0.988	0.012	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.987	0.013	0.000
D86 Sarcoidosis	0.987	0.013	0.000
M20 Acquired deformities of fingers and toes	0.000	0.014	0.986
M20.5 Other deformities of toe(s) (acquired)	0.000	0.016	0.984
L20-L30 Dermatitis and eczema	0.984	0.016	0.000
I73 Other peripheral vascular diseases	0.983	0.017	0.000
Chapter IX Diseases of the circulatory system	0.982	0.018	0.000
E14 Unspecified diabetes mellitus	0.981	0.019	0.000
N40-N51 Diseases of male genital organs	0.000	0.019	0.981
M15-M19 Arthrosis	0.979	0.021	0.000
H36 Retinal disorders in diseases classified elsewhere	0.977	0.023	0.000
H43-H45 Disorders of vitreous body and globe	0.976	0.024	0.000
D86.9 Sarcoidosis, unspecified	0.976	0.024	0.000
M17 Gonarthrosis [arthrosis of knee]	0.975	0.025	0.000
E10.1 With ketoacidosis	0.971	0.029	0.000
I73.9 Peripheral vascular disease, unspecified	0.971	0.029	0.000
N42 Other disorders of prostate	0.000	0.032	0.968
K35-K38 Diseases of appendix	0.961	0.034	0.005
L30 Other dermatitis	0.965	0.035	0.000
M23 Internal derangement of knee	0.965	0.035	0.000
H36.0 Diabetic retinopathy	0.964	0.036	0.000
H02 Other disorders of eyelid	0.964	0.036	0.000
L50-L54 Urticaria and erythema	0.964	0.036	0.000
M06 Other rheumatoid arthritis	0.962	0.038	0.000
M17.9 Gonarthrosis, unspecified	0.960	0.040	0.000
I77 Other disorders of arteries and arterioles	0.959	0.041	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.043	0.957
H43 Disorders of vitreous body	0.955	0.045	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.955	0.045	0.000
K35 Acute appendicitis	0.954	0.046	0.000
E10.2 With renal complications	0.954	0.046	0.000
M70-M79 Other soft tissue disorders	0.953	0.047	0.000
E11.5 With peripheral circulatory complications	0.952	0.048	0.000
K35.9 Acute appendicitis, unspecified	0.950	0.050	0.000
E14.3 With ophthalmic complications	0.949	0.051	0.000
E11.9 Without complications	0.949	0.051	0.000
L30.9 Dermatitis, unspecified	0.949	0.051	0.000
H34 Retinal vascular occlusions	0.948	0.052	0.000
M06.9 Rheumatoid arthritis, unspecified	0.948	0.052	0.000
M34 Systemic sclerosis	0.947	0.053	0.000
M72 Fibroblastic disorders	0.945	0.055	0.000
H02.5 Other disorders affecting eyelid function	0.941	0.059	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.940	0.060	0.000
H43.1 Vitreous haemorrhage	0.940	0.060	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.937	0.063	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.935	0.065	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.932	0.068	0.000
K72 Hepatic failure, not elsewhere classified	0.930	0.070	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.929	0.071	0.000
M22 Disorders of patella	0.925	0.075	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.923	0.077	0.000
M60-M63 Disorders of muscles	0.921	0.079	0.000
M31 Other necrotising vasculopathies	0.920	0.080	0.000
K73 Chronic hepatitis, not elsewhere classified	0.916	0.083	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.915	0.085	0.000
I77.6 Arteritis, unspecified	0.914	0.086	0.000
Chapter II Neoplasms	0.913	0.087	0.000
N30-N39 Other diseases of urinary system	0.000	0.087	0.913
N42.8 Other specified disorders of prostate	0.000	0.087	0.913
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.913	0.087	0.000
Chapter XIV Diseases of the genitourinary system	0.000	0.088	0.912
I74 Arterial embolism and thrombosis	0.912	0.088	0.000
K75.8 Other specified inflammatory liver diseases	0.910	0.090	0.000
H02.1 Ectropion of eyelid	0.910	0.090	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.908	0.092	0.000
E11.3 With ophthalmic complications	0.907	0.093	0.000
K75.9 Inflammatory liver disease, unspecified	0.905	0.095	0.000
H34.8 Other retinal vascular occlusions	0.904	0.096	0.000
L27 Dermatitis due to substances taken internally	0.901	0.099	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.901	0.099	0.000
L40-L45 Papulosquamous disorders	0.899	0.101	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.898	0.102	0.000
M23.3 Other meniscus derangements	0.890	0.110	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.111	0.889
D50-D53 Nutritional anaemias	0.889	0.111	0.000
M20.4 Other hammer toe(s) (acquired)	0.000	0.112	0.888
N39 Other disorders of urinary system	0.000	0.113	0.887
N32 Other disorders of bladder	0.000	0.115	0.885
M07 Psoriatic and enteropathic arthropathies	0.883	0.117	0.000
M17.1 Other primary gonarthrosis	0.883	0.117	0.000
N32.0 Bladder-neck obstruction	0.000	0.118	0.882
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.881	0.119	0.000
M25 Other joint disorders, not elsewhere classified	0.881	0.119	0.000
E70-E90 Metabolic disorders	0.880	0.120	0.000
L52 Erythema nodosum	0.877	0.123	0.000
M11 Other crystal arthropathies	0.876	0.124	0.000
M65-M68 Disorders of synovium and tendon	0.872	0.128	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.870	0.130	0.000
I73.0 Raynaud's syndrome	0.870	0.130	0.000
L94 Other localised connective tissue disorders	0.870	0.130	0.000
H05 Disorders of orbit	0.865	0.135	0.000
K90.9 Intestinal malabsorption, unspecified	0.862	0.138	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.862	0.138	0.000
N39.8 Other specified disorders of urinary system	0.000	0.139	0.861
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.860	0.140	0.000
M62 Other disorders of muscle	0.860	0.140	0.000
L43 Lichen planus	0.860	0.140	0.000
M24 Other specific joint derangements	0.859	0.141	0.000
H02.0 Entropion and trichiasis of eyelid	0.859	0.141	0.000
E50-E64 Other nutritional deficiencies	0.859	0.141	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.858	0.142	0.000
I77.1 Stricture of artery	0.858	0.142	0.000
M10 Gout	0.858	0.142	0.000
L10-L14 Bullous disorders	0.857	0.143	0.000
R30-R39 Symptoms and signs involving the urinary system	0.000	0.146	0.854
L50 Urticaria	0.853	0.147	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.852	0.148	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.852	0.148	0.000
M86-M90 Other osteopathies	0.850	0.150	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.849	0.151	0.000
M31.6 Other giant cell arteritis	0.847	0.153	0.000
E20 Hypoparathyroidism	0.846	0.154	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.843	0.157	0.000
E14.9 Without complications	0.843	0.157	0.000
N48 Other disorders of penis	0.000	0.158	0.842
C02 Malignant neoplasm of other and unspecified parts of tongue	0.838	0.162	0.000
M34.1 CR(E)ST syndrome	0.838	0.162	0.000
D55-D59 Haemolytic anaemias	0.837	0.163	0.000
M17.0 Primary gonarthrosis, bilateral	0.837	0.163	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.836	0.164	0.000
C15-C26 Malignant neoplasms of digestive organs	0.836	0.164	0.000
E10.4 With neurological complications	0.836	0.164	0.000
M23.9 Internal derangement of knee, unspecified	0.835	0.165	0.000
N34 Urethritis and urethral syndrome	0.000	0.167	0.833
Q38-Q45 Other congenital malformations of the digestive system	0.832	0.168	0.000
M67 Other disorders of synovium and tendon	0.828	0.172	0.000
R39 Other symptoms and signs involving the urinary system	0.000	0.172	0.828
H02.3 Blepharochalasis	0.825	0.175	0.000
K72.0 Acute and subacute hepatic failure	0.824	0.175	0.000
H25-H28 Disorders of lens	0.824	0.176	0.000
D83 Common variable immunodeficiency	0.824	0.176	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.176	0.824
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.177	0.823
K35.1 Acute appendicitis with peritoneal abscess	0.822	0.177	0.000
D50 Iron deficiency anaemia	0.822	0.178	0.000
L43.9 Lichen planus, unspecified	0.821	0.179	0.000
Q50-Q56 Congenital malformations of genital organs	0.820	0.180	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.820	0.180	0.000
K72.9 Hepatic failure, unspecified	0.819	0.181	0.000
M34.9 Systemic sclerosis, unspecified	0.819	0.181	0.000
N20-N23 Urolithiasis	0.000	0.182	0.818
E07 Other disorders of thyroid	0.817	0.183	0.000
I70 Atherosclerosis	0.816	0.184	0.000
E10.5 With peripheral circulatory complications	0.816	0.184	0.000
I60-I69 Cerebrovascular diseases	0.813	0.187	0.000
M62.8 Other specified disorders of muscle	0.813	0.187	0.000
M25.9 Joint disorder, unspecified	0.812	0.188	0.000
N36 Other disorders of urethra	0.000	0.189	0.811
N42.9 Disorder of prostate, unspecified	0.000	0.191	0.809
N48.1 Balanoposthitis	0.000	0.191	0.809
C81 Hodgkin's disease	0.806	0.194	0.000
E23 Hypofunction and other disorders of pituitary gland	0.806	0.194	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.804	0.196	0.000
M07.3 Other psoriatic arthropathies	0.803	0.197	0.000
M86 Osteomyelitis	0.803	0.197	0.000
M35.3 Polymyalgia rheumatica	0.802	0.198	0.000
H02.6 Xanthelasma of eyelid	0.802	0.198	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.801	0.199	0.000
N20 Calculus of kidney and ureter	0.000	0.201	0.799
M18 Arthrosis of first carpometacarpal joint	0.798	0.202	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.798	0.202	0.000
C04 Malignant neoplasm of floor of mouth	0.797	0.203	0.000
L89 Decubitus ulcer	0.797	0.203	0.000
D80 Immunodeficiency with predominantly antibody defects	0.796	0.204	0.000
M22.3 Other derangements of patella	0.796	0.204	0.000
K46 Unspecified abdominal hernia	0.000	0.204	0.795
M67.8 Other specified disorders of synovium and tendon	0.795	0.205	0.000
M11.2 Other chondrocalcinosis	0.791	0.209	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.791	0.209	0.000
C25 Malignant neoplasm of pancreas	0.790	0.210	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.790	0.210	0.000
N20.0 Calculus of kidney	0.000	0.210	0.790
H31 Other disorders of choroid	0.789	0.211	0.000
H34.2 Other retinal artery occlusions	0.788	0.212	0.000
E10.0 With coma	0.787	0.213	0.000
C07 Malignant neoplasm of parotid gland	0.787	0.213	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.787	0.213	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.785	0.214	0.000
M25.7 Osteophyte	0.784	0.216	0.000
M22.2 Patellofemoral disorders	0.784	0.216	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.000	0.216	0.784
R33 Retention of urine	0.000	0.216	0.784
E27.3 Drug-induced adrenocortical insufficiency	0.784	0.216	0.000
H46 Optic neuritis	0.784	0.216	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.784	0.216	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.784	0.216	0.000
H01 Other inflammation of eyelid	0.783	0.217	0.000
N81 Female genital prolapse	0.000	0.217	0.783
N81.2 Incomplete uterovaginal prolapse	0.000	0.217	0.783
M76 Enthesopathies of lower limb, excluding foot	0.782	0.218	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.218	0.782
C43 Malignant melanoma of skin	0.782	0.218	0.000
M15 Polyarthrosis	0.781	0.219	0.000
D86.8 Sarcoidosis of other and combined sites	0.779	0.221	0.000
M75 Shoulder lesions	0.777	0.223	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.777	0.223	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.775	0.225	0.000
H30 Chorioretinal inflammation	0.774	0.225	0.000
E13 Other specified diabetes mellitus	0.772	0.228	0.000
N87 Dysplasia of cervix uteri	0.000	0.229	0.771
S40-S49 Injuries to the shoulder and upper arm	0.771	0.229	0.000
E10.8 With unspecified complications	0.770	0.230	0.000
C02.9 Tongue, unspecified	0.769	0.231	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.767	0.233	0.000
M22.8 Other disorders of patella	0.765	0.235	0.000
D50.9 Iron deficiency anaemia, unspecified	0.765	0.235	0.000
E24 Cushing's syndrome	0.764	0.235	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.236	0.764
N34.2 Other urethritis	0.000	0.236	0.764
H43.8 Other disorders of vitreous body	0.764	0.236	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.762	0.238	0.000
L28 Lichen simplex chronicus and prurigo	0.761	0.239	0.000
E78.6 Lipoprotein deficiency	0.761	0.239	0.000
D86.0 Sarcoidosis of lung	0.761	0.239	0.000
L93 Lupus erythematosus	0.761	0.239	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.761	0.239	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.760	0.240	0.000
M06.4 Inflammatory polyarthropathy	0.759	0.241	0.000
E16.1 Other hypoglycaemia	0.757	0.243	0.000
N48.4 Impotence of organic origin	0.000	0.244	0.756
M24.4 Recurrent dislocation and subluxation of joint	0.755	0.245	0.000
M32 Systemic lupus erythematosus	0.755	0.245	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.754	0.246	0.000
H44 Disorders of globe	0.753	0.247	0.000
K36 Other appendicitis	0.750	0.247	0.003
L30.8 Other specified dermatitis	0.752	0.247	0.000
I77.8 Other specified disorders of arteries and arterioles	0.752	0.248	0.000
E27.2 Addisonian crisis	0.752	0.248	0.000
M00-M03 Infectious arthropathies	0.751	0.249	0.000
M34.8 Other forms of systemic sclerosis	0.751	0.249	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.750	0.250	0.000
D84 Other immunodeficiencies	0.750	0.250	0.000
D61 Other aplastic anaemias	0.750	0.250	0.000
E14.1 With ketoacidosis	0.750	0.250	0.000
M86.9 Osteomyelitis, unspecified	0.749	0.251	0.000
H05.0 Acute inflammation of orbit	0.749	0.251	0.000
M35.7 Hypermobility syndrome	0.749	0.251	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.747	0.253	0.000
M12 Other specific arthropathies	0.746	0.254	0.000
H26 Other cataract	0.745	0.255	0.000
L53 Other erythematous conditions	0.745	0.255	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.744	0.256	0.000
L94.0 Localised scleroderma [morphea]	0.744	0.256	0.000
M10.0 Idiopathic gout	0.744	0.256	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.744	0.256	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.743	0.257	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.257	0.743
N39.3 Stress incontinence	0.000	0.258	0.742
I95-I99 Other and unspecified disorders of the circulatory system	0.740	0.260	0.000
S00-S09 Injuries to the head	0.739	0.261	0.000
L81 Other disorders of pigmentation	0.739	0.261	0.000
N36.2 Urethral caruncle	0.000	0.262	0.738
M62.86 Other specified disorders of muscle (Lower leg)	0.737	0.263	0.000
I62 Other nontraumatic intracranial haemorrhage	0.736	0.264	0.000
E20.9 Hypoparathyroidism, unspecified	0.736	0.264	0.000
H26.9 Cataract, unspecified	0.735	0.265	0.000
E78.1 Pure hyperglyceridaemia	0.734	0.266	0.000
D86.3 Sarcoidosis of skin	0.733	0.266	0.000
M75.0 Adhesive capsulitis of shoulder	0.733	0.267	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.268	0.732
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.731	0.269	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.731	0.269	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.269	0.731
M11.26 Other chondrocalcinosis (Lower leg)	0.731	0.269	0.000
N39.0 Urinary tract infection, site not specified	0.000	0.269	0.731
L92.0 Granuloma annulare	0.730	0.270	0.000
N20.1 Calculus of ureter	0.000	0.272	0.728
C25.9 Pancreas, unspecified	0.728	0.272	0.000
L13 Other bullous disorders	0.728	0.272	0.000
E10.6 With other specified complications	0.728	0.272	0.000
C85.1 B-cell lymphoma, unspecified	0.728	0.272	0.000
E11.1 With ketoacidosis	0.727	0.272	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.727	0.272	0.000
E78.5 Hyperlipidaemia, unspecified	0.727	0.273	0.000
I74.8 Embolism and thrombosis of other arteries	0.727	0.273	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.727	0.273	0.000
K73.9 Chronic hepatitis, unspecified	0.726	0.274	0.000
L50.0 Allergic urticaria	0.726	0.274	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.726	0.274	0.000
E29 Testicular dysfunction	0.726	0.274	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.725	0.274	0.000
L80 Vitiligo	0.725	0.275	0.000
Chapter XX External causes of morbidity and mortality	0.725	0.275	0.000
D59 Acquired haemolytic anaemia	0.723	0.277	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.277	0.723
M23.2 Derangement of meniscus due to old tear or injury	0.723	0.277	0.000
H43.9 Disorder of vitreous body, unspecified	0.723	0.277	0.000
I77.2 Rupture of artery	0.722	0.278	0.000
S09 Other and unspecified injuries of head	0.722	0.278	0.000
M35.1 Other overlap syndromes	0.721	0.279	0.000
K74 Fibrosis and cirrhosis of liver	0.721	0.279	0.000
N87.0 Mild cervical dysplasia	0.000	0.280	0.720
M17.3 Other posttraumatic gonarthrosis	0.720	0.280	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.719	0.281	0.000
L51 Erythema multiforme	0.718	0.281	0.000
M25.71 Osteophyte (Shoulder region)	0.718	0.282	0.000
N97 Female infertility	0.000	0.282	0.718
C43.6 Malignant melanoma of upper limb, including shoulder	0.717	0.283	0.000
H04 Disorders of lachrymal system	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.8 Other specified systemic involvement of connective tissue	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
M35.2 Behcet's disease	0.717	0.283	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.283	0.716
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.283	0.716
K93 Disorders of other digestive organs in diseases classified elsewhere	0.707	0.284	0.010
K90.8 Other intestinal malabsorption	0.715	0.284	0.001
K90.3 Pancreatic steatorrhoea	0.715	0.284	0.001
K90.2 Blind loop syndrome, not elsewhere classified	0.715	0.284	0.001
K90.1 Tropical sprue	0.715	0.284	0.001
E35 Disorders of endocrine glands in diseases classified elsewhere	0.716	0.284	0.000
E32 Diseases of thymus	0.716	0.284	0.000
E31 Polyglandular dysfunction	0.716	0.284	0.000
E30 Disorders of puberty, not elsewhere classified	0.716	0.284	0.000
E25 Adrenogenital disorders	0.716	0.284	0.000
N42.2 Atrophy of prostate	0.000	0.284	0.716
E27.5 Adrenomedullary hyperfunction	0.716	0.284	0.000
E27.0 Other adrenocortical overactivity	0.716	0.284	0.000
K44.1 Diaphragmatic hernia with gangrene	0.000	0.284	0.716
S46.2 Injury of muscle and tendon of other parts of biceps	0.716	0.284	0.000
C23 Malignant neoplasm of gallbladder	0.716	0.284	0.000
M23.1 Discoid meniscus (congenital)	0.715	0.285	0.000
D82 Immunodeficiency associated with other major defects	0.714	0.286	0.000
D81 Combined immunodeficiencies	0.714	0.286	0.000
E83 Disorders of mineral metabolism	0.620	0.287	0.094
M09 Juvenile arthritis in diseases classified elsewhere	0.713	0.287	0.000
M08 Juvenile arthritis	0.713	0.287	0.000
N41 Inflammatory diseases of prostate	0.000	0.287	0.713
E11.0 With coma	0.713	0.287	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.713	0.287	0.000
I78 Diseases of capillaries	0.712	0.288	0.000
S90-S99 Injuries to the ankle and foot	0.712	0.288	0.000
K77 Liver disorders in diseases classified elsewhere	0.711	0.288	0.001
K71 Toxic liver disease	0.711	0.288	0.001
K75.3 Granulomatous hepatitis, not elsewhere classified	0.711	0.288	0.000
K75.2 Nonspecific reactive hepatitis	0.711	0.288	0.000
K75.1 Phlebitis of portal vein	0.711	0.288	0.000
N46 Male infertility	0.000	0.290	0.710
E05.8 Other thyrotoxicosis	0.710	0.290	0.000
E11.7 With multiple complications	0.708	0.291	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.708	0.292	0.000
E78.4 Other hyperlipidaemia	0.708	0.292	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.708	0.292	0.000
S20-S29 Injuries to the thorax	0.708	0.292	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.707	0.292	0.000
C13 Malignant neoplasm of hypopharynx	0.707	0.293	0.000
E03.8 Other specified hypothyroidism	0.707	0.293	0.000
S09.9 Unspecified injury of head	0.707	0.293	0.000
C95 Leukaemia of unspecified cell type	0.706	0.293	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.706	0.294	0.000
L84 Corns and callosities	0.705	0.295	0.000
L25 Unspecified contact dermatitis	0.705	0.295	0.000
L24 Irritant contact dermatitis	0.705	0.295	0.000
L26 Exfoliative dermatitis	0.705	0.295	0.000
L22 Diaper [napkin] dermatitis	0.705	0.295	0.000
I73.8 Other specified peripheral vascular diseases	0.705	0.295	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.705	0.295	0.000
E53 Deficiency of other B group vitamins	0.705	0.295	0.000
D50.8 Other iron deficiency anaemias	0.705	0.295	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.705	0.295	0.000
D86.1 Sarcoidosis of lymph nodes	0.705	0.295	0.000
I00-I02 Acute rheumatic fever	0.704	0.296	0.000
H47.2 Optic atrophy	0.704	0.296	0.000
E14.8 With unspecified complications	0.703	0.297	0.000
E14.7 With multiple complications	0.703	0.297	0.000
E14.6 With other specified complications	0.703	0.297	0.000
E14.5 With peripheral circulatory complications	0.703	0.297	0.000
E14.2 Withrenal complications	0.703	0.297	0.000
E14.0 With coma	0.703	0.297	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.000	0.297	0.703
N44 Torsion of testis	0.000	0.297	0.703
E06 Thyroiditis	0.702	0.298	0.000
L81.9 Disorder of pigmentation, unspecified	0.701	0.299	0.000
D83.9 Common variable immunodeficiency, unspecified	0.701	0.299	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.700	0.300	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.700	0.300	0.000
C03 Malignant neoplasm of gum	0.700	0.300	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.700	0.300	0.000
E11.6 With other specified complications	0.699	0.301	0.000
L94.9 Localised connective tissue disorder, unspecified	0.699	0.301	0.000
E61 Deficiency of other nutrient elements	0.699	0.301	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.699	0.301	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.699	0.301	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.698	0.302	0.000
M33 Dermatopolymyositis	0.698	0.302	0.000
L20 Atopic dermatitis	0.698	0.302	0.000
L94.2 Calcinosis cutis	0.698	0.302	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.698	0.302	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.697	0.303	0.000
M13 Other arthritis	0.696	0.303	0.000
H43.2 Crystalline deposits in vitreous body	0.695	0.305	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.306	0.694
S80-S89 Injuries to the knee and lower leg	0.694	0.306	0.000
N42.3 Dysplasia of prostate	0.000	0.306	0.694
C85.7 Other specified types of non-Hodgkin's lymphoma	0.693	0.307	0.000
M14 Arthropathies in other diseases classified elsewhere	0.692	0.307	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.692	0.308	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.692	0.308	0.000
L30.5 Pityriasis alba	0.692	0.308	0.000
L30.4 Erythema intertrigo	0.692	0.308	0.000
L30.3 Infective dermatitis	0.692	0.308	0.000
L30.2 Cutaneous autosensitisation	0.692	0.308	0.000
L30.1 Dyshidrosis [pompholyx]	0.692	0.308	0.000
L30.0 Nummular dermatitis	0.692	0.308	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.691	0.309	0.000
L54 Erythema in diseases classified elsewhere	0.691	0.309	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.691	0.309	0.000
C05 Malignant neoplasm of palate	0.690	0.309	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.690	0.310	0.000
C11 Malignant neoplasm of nasopharynx	0.690	0.310	0.000
M30 Polyarteritis nodosa and related conditions	0.690	0.310	0.000
M06.8 Other specified rheumatoid arthritis	0.690	0.310	0.000
M06.2 Rheumatoid bursitis	0.690	0.310	0.000
M06.1 Adult-onset Still's disease	0.690	0.310	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.690	0.310	0.000
Q53 Undescended testicle	0.689	0.311	0.000
I77.5 Necrosis of artery	0.688	0.312	0.000
I77.4 Coeliac artery compression syndrome	0.688	0.312	0.000
I77.3 Arterial fibromuscular dysplasia	0.688	0.312	0.000
E14.4 With neurological complications	0.687	0.313	0.000
L23 Allergic contact dermatitis	0.687	0.313	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.686	0.314	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations