TreeWAS – Variant ID: rs1358714

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68.2 Hereditary deficiency of other clotting factors	1.000	0.000	0.000
D68 Other coagulation defects	0.775	0.225	0.000
D68.5 Primary Thrombophilia	0.723	0.277	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.680	0.320	0.000
D68.0 Von Willebrand's disease	0.637	0.363	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.584	0.416	0.000
D68.1 Hereditary factor XI deficiency	0.573	0.427	0.000
D68.4 Acquired coagulation factor deficiency	0.531	0.469	0.000
D68.9 Coagulation defect, unspecified	0.464	0.536	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.368	0.632	0.000
D68.8 Other specified coagulation defects	0.340	0.660	0.000
D68.6 Other Thrombophilia	0.298	0.702	0.001
D69 Purpura and other haemorrhagic conditions	0.298	0.702	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.277	0.723	0.000
D66 Hereditary factor VIII deficiency	0.269	0.731	0.000
D69.5 Secondary thrombocytopenia	0.268	0.732	0.000
D67 Hereditary factor IX deficiency	0.252	0.748	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.251	0.749	0.000
D69.2 Other nonthrombocytopenic purpura	0.250	0.750	0.000
D69.8 Other specified haemorrhagic conditions	0.230	0.770	0.000
D69.1 Qualitative platelet defects	0.205	0.795	0.000
D69.4 Other primary thrombocytopenia	0.194	0.806	0.000
I80 Phlebitis and thrombophlebitis	0.166	0.834	0.000
D69.0 Allergic purpura	0.157	0.842	0.000
D69.9 Haemorrhagic condition, unspecified	0.149	0.850	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.147	0.853	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.126	0.874	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.093	0.907	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.092	0.908	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.067	0.933	0.000
C26.0 Intestinal tract, part unspecified	0.000	0.946	0.054
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.948	0.052
C15-C26 Malignant neoplasms of digestive organs	0.000	0.949	0.051
C21 Malignant neoplasm of anus and anal canal	0.000	0.950	0.050
C18 Malignant neoplasm of colon	0.000	0.952	0.048
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.953	0.047
C21.0 Anus, unspecified	0.000	0.953	0.047
C18.6 Descending colon	0.000	0.955	0.045
C18.4 Transverse colon	0.000	0.955	0.045
C23 Malignant neoplasm of gallbladder	0.000	0.956	0.044
C18.5 Splenic flexure	0.000	0.957	0.043
C17 Malignant neoplasm of small intestine	0.000	0.957	0.043
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.957	0.043
C26.9 Ill-defined sites within the digestive system	0.000	0.958	0.042
C21.1 Anal canal	0.000	0.958	0.042
C18.8 Overlapping lesion of colon	0.000	0.960	0.040
C26.8 Overlapping lesion of digestive system	0.000	0.962	0.038
C26.1 Spleen	0.000	0.962	0.038
C25 Malignant neoplasm of pancreas	0.000	0.963	0.037
C17.1 Jejunum	0.000	0.963	0.037
C18.2 Ascending colon	0.000	0.963	0.037
C21.2 Cloacogenic zone	0.000	0.964	0.036
C17.9 Small intestine, unspecified	0.000	0.965	0.035
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.966	0.034
C20 Malignant neoplasm of rectum	0.000	0.966	0.034
C18.9 Colon, unspecified	0.000	0.968	0.032
C17.2 Ileum	0.000	0.968	0.031
C25.1 Body of pancreas	0.000	0.969	0.031
C17.8 Overlapping lesion of small intestine	0.000	0.969	0.031
C17.3 Meckel's diverticulum	0.000	0.969	0.031
C18.1 Appendix	0.000	0.970	0.029
C25.4 Endocrine pancreas	0.000	0.971	0.029
C25.3 Pancreatic duct	0.000	0.972	0.028
C25.9 Pancreas, unspecified	0.000	0.972	0.028
C24.0 Extrahepatic bile duct	0.000	0.972	0.028
C25.2 Tail of pancreas	0.000	0.973	0.027
C25.8 Overlapping lesion of pancreas	0.000	0.973	0.027
C18.0 Caecum	0.000	0.974	0.026
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.975	0.025
C24.8 Overlapping lesion of biliary tract	0.000	0.975	0.025
C17.0 Duodenum	0.000	0.975	0.025
C24.9 Biliary tract, unspecified	0.000	0.977	0.023
C25.0 Head of pancreas	0.000	0.978	0.022
C18.7 Sigmoid colon	0.000	0.979	0.021
C24.1 Ampulla of Vater	0.000	0.979	0.021
C15 Malignant neoplasm of oesophagus	0.000	0.981	0.019
C22.1 Intrahepatic bile duct carcinoma	0.000	0.981	0.019
C22.7 Other specified carcinomas of liver	0.000	0.982	0.018
C22.4 Other sarcomas of liver	0.000	0.982	0.018
C22.3 Angiosarcoma of liver	0.000	0.982	0.018
C22.2 Hepatoblastoma	0.000	0.982	0.018
M13.91 Arthritis, unspecified (Shoulder region)	0.018	0.982	0.000
C25.7 Other parts of pancreas	0.001	0.983	0.016
C16 Malignant neoplasm of stomach	0.000	0.983	0.017
C18.3 Hepatic flexure	0.000	0.984	0.016
C22.0 Liver cell carcinoma	0.000	0.985	0.014
C15.1 Thoracic part of oesophagus	0.000	0.986	0.014
C15.4 Middle third of oesophagus	0.000	0.986	0.014
C15.8 Overlapping lesion of oesophagus	0.000	0.986	0.014
C15.2 Abdominal part of oesophagus	0.000	0.986	0.014
C15.3 Upper third of oesophagus	0.000	0.986	0.014
C16.1 Fundus of stomach	0.000	0.986	0.014
R00.8 Other and unspecified abnormalities of heart beat	0.014	0.986	0.000
C16.5 Lesser curvature of stomach, unspecified	0.000	0.986	0.013
C16.3 Pyloric antrum	0.000	0.987	0.013
C16.8 Overlapping lesion of stomach	0.000	0.987	0.012
C22.9 Liver, unspecified	0.000	0.988	0.012
C15.0 Cervical part of oesophagus	0.000	0.988	0.012
C16.2 Body of stomach	0.000	0.988	0.012
C16.6 Greater curvature of stomach, unspecified	0.000	0.988	0.011
C16.4 Pylorus	0.000	0.989	0.011
C15.9 Oesophagus, unspecified	0.000	0.989	0.011
D69.6 Thrombocytopenia, unspecified	0.011	0.989	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.009	0.991	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.008	0.992	0.000
M25.54 Pain in joint (Hand)	0.008	0.992	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.992	0.008
C15.5 Lower third of oesophagus	0.000	0.992	0.007
K04.7 Periapical abscess without sinus	0.000	0.993	0.007
D63.8 Anaemia in other chronic diseases classified elsewhere	0.006	0.994	0.000
C16.9 Stomach, unspecified	0.000	0.994	0.006
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.994	0.006
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.994	0.006
D80-D89 Certain disorders involving the immune mechanism	0.006	0.994	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.006	0.994	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.995	0.005
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.995	0.005
D63 Anaemia in chronic diseases classified elsewhere	0.005	0.995	0.000
I49.5 Sick sinus syndrome	0.000	0.995	0.005
D60-D64 Aplastic and other anaemias	0.005	0.995	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.995	0.005
D82 Immunodeficiency associated with other major defects	0.005	0.995	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.995	0.005
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
D81 Combined immunodeficiencies	0.004	0.996	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.996	0.004
Z99.1 Dependence on respirator	0.000	0.996	0.004
D83 Common variable immunodeficiency	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.996	0.004
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.996	0.004
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.996	0.004
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.996	0.004
D84 Other immunodeficiencies	0.004	0.996	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.004	0.996	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.004	0.996	0.000
N41.1 Chronic prostatitis	0.000	0.996	0.004
D63.0 Anaemia in neoplastic disease	0.004	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.004	0.996	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
D82.1 Di George's syndrome	0.004	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.996	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.996	0.004
D80 Immunodeficiency with predominantly antibody defects	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.996	0.000
D89.1 Cryoglobulinaemia	0.003	0.996	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.996	0.004
D55-D59 Haemolytic anaemias	0.003	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
J40 Bronchitis, not specified as acute or chronic	0.003	0.997	0.000
D81.9 Combined immunodeficiency, unspecified	0.003	0.997	0.000
D81.8 Other combined immunodeficiencies	0.003	0.997	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.997	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.997	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.997	0.000
D81.4 Nezelof's syndrome	0.003	0.997	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.997	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.997	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.997	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.997	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
D53 Other nutritional anaemias	0.003	0.997	0.000
D53.9 Nutritional anaemia, unspecified	0.003	0.997	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.997	0.003
C16.0 Cardia	0.000	0.997	0.003
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.003	0.997	0.000
D60.8 Other acquired pure red cell aplasias	0.003	0.997	0.000
D60.1 Transient acquired pure red cell aplasia	0.003	0.997	0.000
D60.0 Chronic acquired pure red cell aplasia	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
L43.9 Lichen planus, unspecified	0.000	0.997	0.003
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.997	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.997	0.003
A49.8 Other bacterial infections of unspecified site	0.003	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
R87.6 Abnormal cytological findings	0.000	0.997	0.003
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
D55 Anaemia due to enzyme disorders	0.002	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
I35.0 Aortic (valve) stenosis	0.000	0.997	0.003
D53.8 Other specified nutritional anaemias	0.003	0.997	0.000
D53.2 Scorbutic anaemia	0.003	0.997	0.000
D53.0 Protein deficiency anaemia	0.003	0.997	0.000
I49 Other cardiac arrhythmias	0.000	0.997	0.003
F60 Specific personality disorders	0.003	0.997	0.000
D56 Thalassaemia	0.002	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.997	0.003
F60.6 Anxious [avoidant] personality disorder	0.003	0.997	0.000
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.997	0.003
D86.3 Sarcoidosis of skin	0.002	0.997	0.000
R63.0 Anorexia	0.003	0.997	0.000
K02.9 Dental caries, unspecified	0.000	0.997	0.003
D57 Sickle-cell disorders	0.002	0.997	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.997	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.997	0.000
W19.4 Street and highway	0.000	0.997	0.003
D61 Other aplastic anaemias	0.002	0.997	0.001
M79.00 Rheumatism, unspecified (Multiple sites)	0.002	0.998	0.000
F60.0 Paranoid personality disorder	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
I89.0 Lymphoedema, not elsewhere classified	0.000	0.998	0.002
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.998	0.002
F60.7 Dependent personality disorder	0.002	0.998	0.000
F69 Unspecified disorder of adult personality and behaviour	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.998	0.002
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
D56.3 Thalassaemia trait	0.002	0.998	0.000
F60.2 Dissocial personality disorder	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.998	0.002
I49.2 Junctional premature depolarisation	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
D56.9 Thalassaemia, unspecified	0.002	0.998	0.000
D56.8 Other thalassaemias	0.002	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.998	0.000
D56.2 Delta-beta thalassaemia	0.002	0.998	0.000
D56.0 Alpha thalassaemia	0.002	0.998	0.000
F60.4 Histrionic personality disorder	0.002	0.998	0.000
F60.1 Schizoid personality disorder	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.000	0.998	0.002
K59.8 Other specified functional intestinal disorders	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.998	0.002
G04.1 Tropical spastic paraplegia	0.000	0.998	0.002
G04.0 Acute disseminated encephalitis	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.002
H74.0 Tympanosclerosis	0.000	0.998	0.002
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
F60-F69 Disorders of adult personality and behaviour	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.002	0.998	0.001
D61.3 Idiopathic aplastic anaemia	0.002	0.998	0.001
D61.2 Aplastic anaemia due to other external agents	0.002	0.998	0.001
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
E10.1 With ketoacidosis	0.000	0.998	0.002
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.998	0.002
I49.0 Ventricular fibrillation and flutter	0.000	0.998	0.002
Z00.0 General medical examination	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.998	0.002
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.002	0.998	0.000
F64 Gender identity disorders	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.000	0.998	0.002
I08 Multiple valve diseases	0.000	0.998	0.002
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
H93.1 Tinnitus	0.000	0.998	0.002
D57.1 Sickle-cell anaemia without crisis	0.001	0.998	0.001
D61.0 Constitutional aplastic anaemia	0.001	0.998	0.001
D52 Folate deficiency anaemia	0.002	0.998	0.000
D64 Other anaemias	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.998	0.000
D58.1 Hereditary elliptocytosis	0.001	0.998	0.000
F64.0 Transsexualism	0.002	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.000	0.998	0.002
F68 Other disorders of adult personality and behaviour	0.002	0.998	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.998	0.002
K82.9 Disease of gallbladder, unspecified	0.000	0.998	0.002
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.998	0.002
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.002	0.998	0.000
F65 Disorders of sexual preference	0.002	0.998	0.000
F63 Habit and impulse disorders	0.002	0.998	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.002	0.998	0.000
R09.2 Respiratory arrest	0.000	0.998	0.002
J30.1 Allergic rhinitis due to pollen	0.000	0.998	0.002
D58.2 Other haemoglobinopathies	0.001	0.998	0.001
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.000
R32 Unspecified urinary incontinence	0.002	0.998	0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.002	0.998	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.998	0.002
F61 Mixed and other personality disorders	0.002	0.998	0.000
F64.9 Gender identity disorder, unspecified	0.001	0.998	0.000
F64.8 Other gender identity disorders	0.001	0.998	0.000
F64.2 Gender identity disorder of childhood	0.001	0.998	0.000
F64.1 Dual-role transvestism	0.001	0.998	0.000
Z89 Acquired absence of limb	0.002	0.998	0.000
K04.0 Pulpitis	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
Q24.5 Malformation of coronary vessels	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.001	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.001	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.001	0.998	0.000
D64.4 Congenital dyserythropoietic anaemia	0.001	0.998	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.001	0.998	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.001	0.998	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.001	0.998	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.001	0.998	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.000	0.998	0.002
Z86.7 Personal history of diseases of the circulatory system	0.002	0.998	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
E78.8 Other disorders of lipoprotein metabolism	0.000	0.998	0.002
F62.9 Enduring personality change, unspecified	0.001	0.998	0.000
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.002	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.998	0.002
D58.0 Hereditary spherocytosis	0.001	0.998	0.001
F62.8 Other enduring personality changes	0.001	0.998	0.000
F62.1 Enduring personality change after psychiatric illness	0.001	0.998	0.000
F62.0 Enduring personality change after catastrophic experience	0.001	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.000	0.998	0.002
W19.2 School, other institution and public administrative area	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
D64.3 Other sideroblastic anaemias	0.001	0.998	0.000
D64.0 Hereditary sideroblastic anaemia	0.001	0.998	0.000
F63.9 Habit and impulse disorder, unspecified	0.001	0.998	0.000
F63.8 Other habit and impulse disorders	0.001	0.998	0.000
F63.3 Trichotillomania	0.001	0.998	0.000
F63.2 Pathological stealing [kleptomania]	0.001	0.998	0.000
F63.1 Pathological fire-setting [pyromania]	0.001	0.998	0.000
F63.0 Pathological gambling	0.001	0.998	0.000
F65.9 Disorder of sexual preference, unspecified	0.001	0.998	0.000
F65.8 Other disorders of sexual preference	0.001	0.998	0.000
F65.6 Multiple disorders of sexual preference	0.001	0.998	0.000
F65.5 Sadomasochism	0.001	0.998	0.000
F65.4 Paedophilia	0.001	0.998	0.000
F65.3 Voyeurism	0.001	0.998	0.000
F65.2 Exhibitionism	0.001	0.998	0.000
F65.1 Fetishistic transvestism	0.001	0.998	0.000
F65.0 Fetishism	0.001	0.998	0.000
F66.9 Psychosexual development disorder, unspecified	0.001	0.998	0.000
F66.8 Other psychosexual development disorders	0.001	0.998	0.000
F66.2 Sexual relationship disorder	0.001	0.998	0.000
F66.1 Egodystonic sexual orientation	0.001	0.998	0.000
F66.0 Sexual maturation disorder	0.001	0.998	0.000
I89.1 Lymphangitis	0.001	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.000	0.998	0.002
Q05 Spina bifida	0.000	0.998	0.002
D64.8 Other specified anaemias	0.001	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.001	0.998	0.000
Z89.2 Acquired absence of upper limb above wrist	0.001	0.998	0.000
J84.8 Other specified interstitial pulmonary diseases	0.001	0.998	0.000
W19.3 Sports and athletics area	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.002	0.998	0.000
D22.5 Melanocytic naevi of trunk	0.002	0.998	0.000
D41.4 Bladder	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.998	0.001
J84.9 Interstitial pulmonary disease, unspecified	0.001	0.998	0.000
K43 Ventral hernia	0.001	0.998	0.000
W19 Unspecified fall	0.000	0.998	0.002
Z89.3 Acquired absence of both upper limbs [any level]	0.001	0.999	0.000
Z89.1 Acquired absence of hand and wrist	0.001	0.999	0.000
Z97.4 Presence of external hearing-aid	0.000	0.999	0.001
I30.1 Infective pericarditis	0.001	0.999	0.000
W19.1 Residential institution	0.000	0.999	0.001
Z89.8 Acquired absence of upper and lower limbs [any level]	0.001	0.999	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.001	0.999	0.000
I08.8 Other multiple valve diseases	0.000	0.999	0.001
M16.7 Other secondary coxarthrosis	0.000	0.999	0.001
N41 Inflammatory diseases of prostate	0.000	0.999	0.001
S22.00 Fracture of thoracic vertebra (closed)	0.001	0.999	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.999	0.001
Q05.4 Unspecified spina bifida with hydrocephalus	0.000	0.999	0.001
W19.6 Industrial and construction area	0.000	0.999	0.001
M13.89 Other specified arthritis (Site unspecified)	0.001	0.999	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.999	0.001
G97.8 Other postprocedural disorders of nervous system	0.000	0.999	0.001
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.999	0.000
D51.2 Transcobalamin II deficiency	0.001	0.999	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.000	0.999	0.001
Q05.7 Lumbar spina bifida without hydrocephalus	0.000	0.999	0.001
Q05.6 Thoracic spina bifida without hydrocephalus	0.000	0.999	0.001
Q05.5 Cervical spina bifida without hydrocephalus	0.000	0.999	0.001
Q05.3 Sacral spina bifida with hydrocephalus	0.000	0.999	0.001
Q05.2 Lumbar spina bifida with hydrocephalus	0.000	0.999	0.001
Q05.1 Thoracic spina bifida with hydrocephalus	0.000	0.999	0.001
Q05.0 Cervical spina bifida with hydrocephalus	0.000	0.999	0.001
Q24.9 Congenital malformation of the heart, unspecified	0.001	0.999	0.000
Y57.5 X-ray contrast media	0.001	0.999	0.000
J84 Other interstitial pulmonary diseases	0.001	0.999	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.001	0.999	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.001	0.999	0.000
L91.8 Other hypertrophic disorders of skin	0.000	0.999	0.001
S01.5 Open wound of lip and oral cavity	0.000	0.999	0.001
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.000	0.999	0.001
X49.9 Unspecified place	0.001	0.999	0.000
Q07 Other congenital malformations of nervous system	0.000	0.999	0.001
Q24 Other congenital malformations of heart	0.001	0.999	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.001	0.999	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.999	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.999	0.001
I49.4 Other and unspecified premature depolarisation	0.001	0.999	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.001	0.999	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.001	0.999	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.001	0.999	0.000
K43.4 Parastomal hernia with gangrene	0.001	0.999	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.001	0.999	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.001	0.999	0.000
K43.1 Ventral hernia with gangrene	0.001	0.999	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.999	0.001
W19.8 Other specified place	0.000	0.999	0.001
W19.5 Trade and service area	0.000	0.999	0.001
W19.0 Home	0.000	0.999	0.001
W19.7 Farm	0.000	0.999	0.001
Z59.8 Other problems relating to housing and economic circumstances	0.001	0.999	0.000
D05.0 Lobular carcinoma in situ	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.999	0.001
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.999	0.001
N41.3 Prostatocystitis	0.000	0.999	0.001
N41.2 Abscess of prostate	0.000	0.999	0.001
I49.1 Atrial premature depolarisation	0.000	0.999	0.001
J04.0 Acute laryngitis	0.000	0.999	0.001
Q07.8 Other specified congenital malformations of nervous system	0.000	0.999	0.001
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.999	0.001
E10.0 With coma	0.000	0.999	0.001
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.999	0.001
G31.8 Other specified degenerative diseases of nervous system	0.000	0.999	0.001
Q24.0 Dextrocardia	0.001	0.999	0.000
D26.1 Corpus uteri	0.001	0.999	0.000
D59.1 Other autoimmune haemolytic anaemias	0.001	0.999	0.001
D76.3 Other histiocytosis syndromes	0.001	0.999	0.000
K25.7 Chronic without haemorrhage or perforation	0.001	0.999	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.999	0.001
O90.2 Haematoma of obstetric wound	0.000	0.999	0.001
Q07.9 Congenital malformation of nervous system, unspecified	0.000	0.999	0.001
I82 Other venous embolism and thrombosis	0.001	0.999	0.000
L43 Lichen planus	0.000	0.999	0.001
W19.09 Unspecified fall; Home; During unspecified activity	0.000	0.999	0.001
W19.08 Unspecified fall; Home; While engaged in other specified activities	0.000	0.999	0.001
W19.59 Unspecified fall; Trade and service area; During unspecified activity	0.000	0.999	0.001
W19.81 Unspecified fall; Other specified places; While engaged in leisure activity	0.000	0.999	0.001
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.999	0.001
Q24.4 Congenital subaortic stenosis	0.001	0.999	0.000
Q24.3 Pulmonary infundibular stenosis	0.001	0.999	0.000
Q24.2 Cor triatriatum	0.001	0.999	0.000
Q24.1 Levocardia	0.001	0.999	0.000
Z04.5 Examination and observation following other inflicted injury	0.000	0.999	0.001
Q24.6 Congenital heart block	0.001	0.999	0.000
T79.8 Other early complications of trauma	0.000	0.999	0.001
Z89.6 Acquired absence of leg above knee	0.001	0.999	0.000
I99 Other and unspecified disorders of circulatory system	0.001	0.999	0.000
J84.0 Alveolar and parietoalveolar conditions	0.001	0.999	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.001	0.999	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.000	0.999	0.001
S56 Injury of muscle and tendon at forearm level	0.000	0.999	0.001
F80.1 Expressive language disorder	0.001	0.999	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.999	0.001
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.999	0.001
H21.0 Hyphaema	0.000	0.999	0.001
I67.2 Cerebral atherosclerosis	0.000	0.999	0.001
I82.0 Budd-Chiari syndrome	0.001	0.999	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.000	0.999	0.001
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations