TreeWAS – Variant ID: rs1371799

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I73.0 Raynaud's syndrome	0.000	0.970	0.030
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.974	0.026
I08 Multiple valve diseases	0.000	0.980	0.020
K80.4 Calculus of bile duct with cholecystitis	0.000	0.980	0.020
I08.9 Multiple valve disease, unspecified	0.000	0.982	0.018
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.983	0.017
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.984	0.016
I33.0 Acute and subacute infective endocarditis	0.000	0.984	0.016
I08.8 Other multiple valve diseases	0.000	0.985	0.015
I08.0 Disorders of both mitral and aortic valves	0.000	0.985	0.015
E83.1 Disorders of iron metabolism	0.000	0.985	0.015
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.986	0.014
E87.6 Hypokalaemia	0.000	0.987	0.013
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.987	0.013
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.012	0.988	0.000
F31 Bipolar affective disorder	0.000	0.988	0.012
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.011	0.989	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.011	0.989	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.989	0.011
I73 Other peripheral vascular diseases	0.000	0.989	0.011
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.011	0.989	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.990	0.010
E87.7 Fluid overload	0.000	0.990	0.010
F31.9 Bipolar affective disorder, unspecified	0.000	0.990	0.010
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.990	0.010
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.010	0.990	0.000
E87.3 Alkalosis	0.000	0.990	0.010
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.990	0.010
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.990	0.010
I05-I09 Chronic rheumatic heart diseases	0.000	0.991	0.009
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.009	0.991	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.009	0.991	0.000
F31.8 Other bipolar affective disorders	0.000	0.991	0.009
S66.8 Injury of other muscles and tendons at wrist and hand level	0.009	0.991	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.991	0.009
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.991	0.009
F31.7 Bipolar affective disorder, currently in remission	0.000	0.991	0.009
M19.0 Primary arthrosis of other joints	0.000	0.991	0.009
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.991	0.008
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.991	0.009
E87.5 Hyperkalaemia	0.000	0.991	0.009
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.992	0.008
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.008	0.992	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.992	0.008
I42.0 Dilated cardiomyopathy	0.000	0.992	0.008
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.992	0.008
I73.8 Other specified peripheral vascular diseases	0.000	0.992	0.008
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.992	0.008
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.992	0.008
E87.0 Hyperosmolality and hypernatraemia	0.000	0.992	0.008
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.992	0.008
I09 Other rheumatic heart diseases	0.000	0.992	0.008
I06 Rheumatic aortic valve diseases	0.000	0.992	0.008
I42 Cardiomyopathy	0.000	0.992	0.008
E87.4 Mixed disorder of acid-base balance	0.000	0.992	0.007
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.993	0.007
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.993	0.007
I42.2 Other hypertrophic cardiomyopathy	0.000	0.993	0.007
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.993	0.007
I06.0 Rheumatic aortic stenosis	0.000	0.993	0.007
I33 Acute and subacute endocarditis	0.000	0.993	0.007
M19.08 Primary arthrosis of other joints (Other)	0.000	0.993	0.007
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.993	0.007
I09.9 Rheumatic heart disease, unspecified	0.000	0.993	0.007
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.993	0.007
D48.1 Connective and other soft tissue	0.000	0.993	0.007
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.993	0.006
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.994	0.006
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.994	0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.994	0.006
I05 Rheumatic mitral valve diseases	0.000	0.994	0.006
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.994	0.006
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.994	0.006
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.006	0.994	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.994	0.006
I09.8 Other specified rheumatic heart diseases	0.000	0.994	0.006
I09.2 Chronic rheumatic pericarditis	0.000	0.994	0.006
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.994	0.006
I09.0 Rheumatic myocarditis	0.000	0.994	0.006
I42.4 Endocardial fibroelastosis	0.000	0.994	0.006
I06.8 Other rheumatic aortic valve diseases	0.000	0.994	0.006
I05.9 Mitral valve disease, unspecified	0.000	0.994	0.006
I42.8 Other cardiomyopathies	0.000	0.994	0.006
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.994	0.006
I06.1 Rheumatic aortic insufficiency	0.000	0.994	0.005
T39.4 Antirheumatics, not elsewhere classified	0.000	0.994	0.005
T39.2 Pyrazolone derivatives	0.000	0.994	0.005
T46.1 Calcium-channel blockers	0.000	0.994	0.005
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.995	0.005
I33.9 Acute endocarditis, unspecified	0.000	0.995	0.005
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
O46.9 Antepartum haemorrhage, unspecified	0.005	0.995	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.995	0.005
T36 Poisoning by systemic antibiotics	0.000	0.995	0.005
S06.2 Diffuse brain injury	0.000	0.995	0.005
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.995	0.005
I73.9 Peripheral vascular disease, unspecified	0.000	0.995	0.005
I42.5 Other restrictive cardiomyopathy	0.000	0.995	0.005
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.995	0.005
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.995	0.005
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.995	0.005
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.995	0.005
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.995	0.005
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.995	0.005
T46.7 Peripheral vasodilators	0.000	0.995	0.005
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.995	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.995	0.005
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.995	0.005
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.995	0.005
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.995	0.005
I05.8 Other mitral valve diseases	0.000	0.995	0.004
T47.0 Histamine H(2)-receptor antagonists	0.000	0.995	0.005
I42.9 Cardiomyopathy, unspecified	0.000	0.995	0.005
I07.9 Tricuspid valve disease, unspecified	0.000	0.995	0.004
I07.8 Other tricuspid valve diseases	0.000	0.995	0.004
I07.2 Tricuspid stenosis with insufficiency	0.000	0.995	0.004
I07.0 Tricuspid stenosis	0.000	0.995	0.004
I42.6 Alcoholic cardiomyopathy	0.000	0.995	0.004
T36.3 Macrolides	0.000	0.996	0.004
T47.2 Stimulant laxatives	0.000	0.996	0.004
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.996	0.004
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.996	0.004
D48.6 Breast	0.000	0.996	0.004
T42.1 Iminostilbenes	0.000	0.996	0.004
D48.0 Bone and articular cartilage	0.000	0.996	0.004
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.004
T36.4 Tetracyclines	0.000	0.996	0.004
T47.4 Other laxatives	0.000	0.996	0.004
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.004
F30-F39 Mood [affective] disorders	0.000	0.996	0.004
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.996	0.004
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.996	0.004
T47.7 Emetics	0.000	0.996	0.004
T47.5 Digestants	0.000	0.996	0.004
T47.3 Saline and osmotic laxatives	0.000	0.996	0.004
T36.0 Penicillins	0.000	0.996	0.004
T47.6 Antidiarrhoeal drugs	0.000	0.996	0.004
I05.2 Mitral stenosis with insufficiency	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.000	0.996	0.004
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.996	0.004
D48.7 Other specified sites	0.000	0.996	0.004
T42.3 Barbiturates	0.000	0.996	0.004
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.996	0.004
T36.9 Systemic antibiotic, unspecified	0.000	0.996	0.004
T36.8 Other systemic antibiotics	0.000	0.996	0.004
T36.7 Antifungal antibiotics, systemically used	0.000	0.996	0.004
T36.6 Rifamycins	0.000	0.996	0.004
T36.5 Aminoglycosides	0.000	0.996	0.004
T36.2 Chloramphenicol group	0.000	0.996	0.004
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.996	0.004
T40.6 Other and unspecified narcotics	0.000	0.996	0.004
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.996	0.004
I05.0 Mitral stenosis	0.000	0.996	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.996	0.004
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.996	0.004
I27.0 Primary pulmonary hypertension	0.000	0.996	0.004
D48.4 Peritoneum	0.000	0.996	0.004
G37.9 Demyelinating disease of central nervous system, unspecified	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.996	0.004
T42.2 Succinimides and oxazolidinediones	0.000	0.996	0.004
F30 Manic episode	0.000	0.996	0.004
T48.5 Anti-common-cold drugs	0.000	0.996	0.004
F38 Other mood [affective] disorders	0.000	0.996	0.004
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.996	0.004
F39 Unspecified mood [affective] disorder	0.000	0.996	0.004
F30.0 Hypomania	0.000	0.996	0.004
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.996	0.004
I27.2 Other secondary pulmonary hypertension	0.000	0.996	0.004
T40.2 Other opioids	0.000	0.996	0.004
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.996	0.003
L53.9 Erythematous condition, unspecified	0.000	0.997	0.003
T42.4 Benzodiazepines	0.000	0.997	0.003
D68.8 Other specified coagulation defects	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.003
T48.4 Expectorants	0.000	0.997	0.003
T48.3 Antitussives	0.000	0.997	0.003
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.003
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.003
T48.0 Oxytocic drugs	0.000	0.997	0.003
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.997	0.003
M22.4 Chondromalacia patellae	0.000	0.997	0.003
I07.1 Tricuspid insufficiency	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
T37.5 Antiviral drugs	0.000	0.997	0.003
T37.4 Anthelminthics	0.000	0.997	0.003
T37.3 Other antiprotozoal drugs	0.000	0.997	0.003
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
T37.1 Antimycobacterial drugs	0.000	0.997	0.003
T37.0 Sulphonamides	0.000	0.997	0.003
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
D48.3 Retroperitoneum	0.000	0.997	0.003
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.997	0.003
T39.0 Salicylates	0.000	0.997	0.003
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
I95.1 Orthostatic hypotension	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.997	0.003
D48.5 Skin	0.000	0.997	0.003
F30.1 Mania without psychotic symptoms	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
F38.8 Other specified mood [affective] disorders	0.000	0.997	0.003
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.003
T40.8 Lysergide [LSD]	0.000	0.997	0.003
T40.7 Cannabis (derivatives)	0.000	0.997	0.003
T40.0 Opium	0.000	0.997	0.003
H35.4 Peripheral retinal degeneration	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.000	0.997	0.003
T49.8 Other topical agents	0.000	0.997	0.003
T49.7 Dental drugs, topically applied	0.000	0.997	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.003
T49.2 Local astringents and local detergents	0.000	0.997	0.003
T49.1 Antipruritics	0.000	0.997	0.003
F38.0 Other single mood [affective] disorders	0.000	0.997	0.003
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.003	0.997	0.000
I27 Other pulmonary heart diseases	0.000	0.997	0.003
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.997	0.003
F34 Persistent mood [affective] disorders	0.000	0.997	0.003
F33 Recurrent depressive disorder	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
F30.8 Other manic episodes	0.000	0.997	0.003
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.997	0.003
M89.98 Disorder of bone, unspecified (Other)	0.000	0.997	0.003
F38.1 Other recurrent mood [affective] disorders	0.000	0.997	0.003
M89.9 Disorder of bone, unspecified	0.000	0.997	0.003
T40.1 Heroin	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
R94.3 Abnormal results of cardiovascular function studies	0.000	0.997	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.003
M25.76 Osteophyte (Lower leg)	0.003	0.997	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.997	0.003
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.997	0.003
T40.3 Methadone	0.000	0.997	0.003
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
I05.1 Rheumatic mitral insufficiency	0.000	0.997	0.002
U88 Agent resistant to multiple antibiotics	0.000	0.997	0.003
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.003	0.997	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.000	0.997	0.003
T40.5 Cocaine	0.000	0.997	0.003
G44.2 Tension-type headache	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
O46.0 Antepartum haemorrhage with coagulation defect	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
U80.1 Methicillin resistant agent	0.000	0.997	0.003
M88.9 Paget's disease of bone, unspecified	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
S06 Intracranial injury	0.000	0.997	0.003
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.997	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.002
E27 Other disorders of adrenal gland	0.003	0.997	0.000
F33.8 Other recurrent depressive disorders	0.000	0.997	0.002
N64.5 Other signs and symptoms in breast	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.997	0.002
I27.9 Pulmonary heart disease, unspecified	0.000	0.997	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.998	0.002
C78.7 Secondary malignant neoplasm of liver	0.000	0.998	0.002
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.000	0.998	0.002
E27.2 Addisonian crisis	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.998	0.002
F34.8 Other persistent mood [affective] disorders	0.000	0.998	0.002
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.002
L40.5 Arthropathic psoriasis	0.000	0.998	0.002
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
R44.1 Visual hallucinations	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.002
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
F34.0 Cyclothymia	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.000	0.998	0.002
A63.0 Anogenital (venereal) warts	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.000	0.998	0.002
F34.1 Dysthymia	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
U51 Admission status on psychiatric patients	0.000	0.998	0.002
K60.2 Anal fissure, unspecified	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.998	0.002
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.998	0.002
M88.98 Paget's disease of bone, unspecified (Other)	0.002	0.998	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.002	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.002	0.998	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.002	0.998	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.002	0.998	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.998	0.002
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
D68 Other coagulation defects	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.000	0.998	0.002
U50 Level of care administered to neonates	0.000	0.998	0.002
U07 Emergency use of U07	0.000	0.998	0.002
U06 Emergency use of U06	0.000	0.998	0.002
U04 Severe acute respiratory syndrome [SARS]	0.000	0.998	0.002
U52 First in a series of a regular day/night admissions	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
R09.1 Pleurisy	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.002
I27.8 Other specified pulmonary heart diseases	0.000	0.998	0.002
L85.8 Other specified epidermal thickening	0.000	0.998	0.002
S06.3 Focal brain injury	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
D68.6 Other Thrombophilia	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
E83 Disorders of mineral metabolism	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.998	0.002
K56.2 Volvulus	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.000	0.998	0.002
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
U51.2 Previously admitted to a psychiatric hospital of another provider	0.000	0.998	0.002
U81.0 Vancomycin resistant agent	0.000	0.998	0.002
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.998	0.002
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.998	0.002
U84 Resistance to other antimicrobial drugs	0.000	0.998	0.002
U83 Resistance to other antibiotics	0.000	0.998	0.002
U82 Resistance to betalactam antibiotics	0.000	0.998	0.002
U85 Resistance to antineoplastic drugs	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
O73.0 Retained placenta, without haemorrhage	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.001
R44 Other symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
Chapter XXII Codes for special purposes	0.000	0.998	0.002
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.002
U81.8 Agent resistant to other vancomycin-related antibiotic	0.000	0.998	0.002
R44.2 Other hallucinations	0.002	0.998	0.000
S06.0 Concussion	0.000	0.998	0.002
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.000	0.998	0.001
U06.9 Emergency use of U06.9	0.000	0.998	0.001
U06.8 Emergency use of U06.8	0.000	0.998	0.001
U06.7 Emergency use of U06.7	0.000	0.998	0.001
U06.6 Emergency use of U06.6	0.000	0.998	0.001
U06.5 Emergency use of U06.5	0.000	0.998	0.001
U06.4 Emergency use of U06.4	0.000	0.998	0.001
U06.3 Emergency use of U06.3	0.000	0.998	0.001
U06.2 Emergency use of U06.2	0.000	0.998	0.001
U06.1 Emergency use of U06.1	0.000	0.998	0.001
U06.0 Emergency use of U06.0	0.000	0.998	0.001
U07.9 Emergency use of U07.9	0.000	0.998	0.001
U07.8 Emergency use of U07.8	0.000	0.998	0.001
U07.7 Emergency use of U07.7	0.000	0.998	0.001
U07.6 Emergency use of U07.6	0.000	0.998	0.001
U07.5 Emergency use of U07.5	0.000	0.998	0.001
U07.4 Emergency use of U07.4	0.000	0.998	0.001
U07.3 Emergency use of U07.3	0.000	0.998	0.001
U07.2 Emergency use of U07.2	0.000	0.998	0.001
U07.1 Emergency use of U07.1	0.000	0.998	0.001
U07.0 Emergency use of U07.0	0.000	0.998	0.001
U50.9 Inquest Adjourned Death	0.000	0.998	0.001
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.000	0.998	0.001
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.000	0.998	0.001
U50.1 Level of care administered to neonates (Special Care)	0.000	0.998	0.001
U50.0 Level of care administered to neonates (Normal Care)	0.000	0.998	0.001
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.001
Z51.9 Medical care, unspecified	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.001
S06.5 Traumatic subdural haemorrhage	0.000	0.998	0.002
S64.1 Injury of median nerve at wrist and hand level	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.001
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.998	0.001
L85 Other epidermal thickening	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.000	0.998	0.002
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
E83.8 Other disorders of mineral metabolism	0.000	0.998	0.002
E83.2 Disorders of zinc metabolism	0.000	0.998	0.002
E83.0 Disorders of copper metabolism	0.000	0.998	0.002
N83.1 Corpus luteum cyst	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.001
N43.3 Hydrocele, unspecified	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.001
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.998	0.002
K56.4 Other impaction of intestine	0.000	0.998	0.002
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.998	0.001
U82.8 Resistance to other betalactam antibiotics	0.000	0.998	0.001
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.998	0.001
U82.1 Resistance to methicillin	0.000	0.998	0.001
U82.0 Resistance to penicillin	0.000	0.998	0.001
U83.9 Resistance to unspecified antibiotic	0.000	0.998	0.001
U83.8 Resistance to other single specified antibiotic	0.000	0.998	0.001
U83.7 Resistance to multiple antibiotics	0.000	0.998	0.001
U83.2 Resistance to quinolones	0.000	0.998	0.001
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.998	0.001
U83.0 Resistance to vancomycin	0.000	0.998	0.001
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.998	0.001
U84.8 Resistance to other specified antimicrobial drug	0.000	0.998	0.001
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.998	0.001
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.998	0.001
U84.2 Resistance to antiviral drug(s)	0.000	0.998	0.001
U84.1 Resistance to antifungal drug(s)	0.000	0.998	0.001
U84.0 Resistance to antiparasitic drug(s)	0.000	0.998	0.001
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.001
M25.37 Other instability of joint (Ankle and foot)	0.002	0.998	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.002	0.998	0.000
K56.0 Paralytic ileus	0.000	0.998	0.002
J33.8 Other polyp of sinus	0.000	0.998	0.002
T45.5 Anticoagulants	0.001	0.998	0.001
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.000	0.998	0.001
S64.2 Injury of radial nerve at wrist and hand level	0.001	0.998	0.000
W18.3 Sports and athletics area	0.001	0.998	0.000
M79.18 Myalgia (Other)	0.000	0.998	0.001
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.001
S64 Injury of nerves at wrist and hand level	0.002	0.998	0.000
L93.0 Discoid lupus erythematosus	0.001	0.999	0.000
R85.5 Abnormal microbiological findings	0.000	0.999	0.001
F45.8 Other somatoform disorders	0.001	0.999	0.000
G37.5 Concentric sclerosis [Balo]	0.001	0.999	0.000
G37.4 Subacute necrotising myelitis	0.001	0.999	0.000
G37.2 Central pontine myelinolysis	0.001	0.999	0.000
G37.1 Central demyelination of corpus callosum	0.001	0.999	0.000
G37.0 Diffuse sclerosis	0.001	0.999	0.000
L85.3 Xerosis cutis	0.000	0.999	0.001
L85.2 Keratosis punctata (palmaris et plantaris)	0.000	0.999	0.001
L85.0 Acquired ichthyosis	0.000	0.999	0.001
M25.34 Other instability of joint (Hand)	0.001	0.999	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations