TreeWAS – Variant ID: rs138570705

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.995	0.005
I30-I52 Other forms of heart disease	0.994	0.006
I10-I15 Hypertensive diseases	0.988	0.012
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.982	0.018
I10 Essential (primary) hypertension	0.980	0.020
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.979	0.021
K80 Cholelithiasis	0.978	0.022
Chapter XI Diseases of the digestive system	0.976	0.024
I34 Nonrheumatic mitral valve disorders	0.976	0.024
K80.1 Calculus of gallbladder with other cholecystitis	0.973	0.027
Chapter X Diseases of the respiratory system	0.972	0.028
I51 Complications and ill-defined descriptions of heart disease	0.968	0.032
T81 Complications of procedures, not elsewhere classified	0.959	0.041
I34.0 Mitral (valve) insufficiency	0.958	0.042
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.952	0.048
I51.7 Cardiomegaly	0.951	0.049
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.945	0.055
Chapter V Mental and behavioural disorders	0.944	0.056
I44 Atrioventricular and left bundle-branch block	0.939	0.061
S00-S09 Injuries to the head	0.939	0.061
J09-J18 Influenza and pneumonia	0.936	0.064
J80-J84 Other respiratory diseases principally affecting the interstitium	0.921	0.079
I35 Nonrheumatic aortic valve disorders	0.919	0.081
J20-J22 Other acute lower respiratory infections	0.916	0.084
Chapter XXII Codes for special purposes	0.916	0.084
K80.0 Calculus of gallbladder with acute cholecystitis	0.914	0.086
K35-K38 Diseases of appendix	0.911	0.089
Chapter VI Diseases of the nervous system	0.909	0.091
Chapter VIII Diseases of the ear and mastoid process	0.906	0.094
J18 Pneumonia, organism unspecified	0.904	0.096
Chapter XX External causes of morbidity and mortality	0.900	0.100
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.899	0.101
I20-I25 Ischaemic heart diseases	0.892	0.108
I44.7 Left bundle-branch block, unspecified	0.889	0.111
F30-F39 Mood [affective] disorders	0.887	0.113
K81 Cholecystitis	0.882	0.118
K35 Acute appendicitis	0.878	0.122
J22 Unspecified acute lower respiratory infection	0.876	0.124
H65-H75 Diseases of middle ear and mastoid	0.870	0.130
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.868	0.132
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.859	0.140
I35.1 Aortic (valve) insufficiency	0.859	0.141
S06 Intracranial injury	0.857	0.142
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.856	0.144
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.855	0.145
K81.0 Acute cholecystitis	0.855	0.145
K35.9 Acute appendicitis, unspecified	0.853	0.147
I30 Acute pericarditis	0.850	0.150
S02 Fracture of skull and facial bones	0.850	0.150
D80-D89 Certain disorders involving the immune mechanism	0.848	0.152
I05-I09 Chronic rheumatic heart diseases	0.837	0.163
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.837	0.163
J18.9 Pneumonia, unspecified	0.834	0.166
G35-G37 Demyelinating diseases of the central nervous system	0.834	0.166
J18.0 Bronchopneumonia, unspecified	0.833	0.167
I24 Other acute ischaemic heart diseases	0.827	0.172
Chapter IV Endocrine, nutritional and metabolic diseases	0.825	0.175
F29 Unspecified nonorganic psychosis	0.824	0.176
K82 Other diseases of gallbladder	0.823	0.177
J81 Pulmonary oedema	0.822	0.178
S40-S49 Injuries to the shoulder and upper arm	0.815	0.185
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.814	0.186
T81.4 Infection following a procedure, not elsewhere classified	0.813	0.187
E78.0 Pure hypercholesterolaemia	0.812	0.188
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.811	0.189
E70-E90 Metabolic disorders	0.810	0.190
G40-G47 Episodic and paroxysmal disorders	0.810	0.190
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.809	0.191
U80 Agent resistant to penicillin and related antibiotics	0.807	0.193
K65-K67 Diseases of peritoneum	0.799	0.201
Chapter I Certain infectious and parasitic diseases	0.794	0.206
F23 Acute and transient psychotic disorders	0.791	0.209
I36 Nonrheumatic tricuspid valve disorders	0.789	0.211
F30 Manic episode	0.788	0.212
T85 Complications of other internal prosthetic devices, implants and grafts	0.787	0.213
J84 Other interstitial pulmonary diseases	0.786	0.214
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.785	0.215
D86 Sarcoidosis	0.785	0.215
H65 Nonsuppurative otitis media	0.782	0.218
I34.1 Mitral (valve) prolapse	0.778	0.221
I51.4 Myocarditis, unspecified	0.778	0.222
G80-G83 Cerebral palsy and other paralytic syndromes	0.777	0.223
I35.9 Aortic valve disorder, unspecified	0.774	0.226
G40 Epilepsy	0.772	0.228
S90-S99 Injuries to the ankle and foot	0.771	0.229
I24.8 Other forms of acute ischaemic heart disease	0.765	0.235
T31 Burns classified according to extent of body surface involved	0.762	0.238
K80.4 Calculus of bile duct with cholecystitis	0.761	0.239
I70-I79 Diseases of arteries, arterioles and capillaries	0.761	0.239
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.758	0.242
I44.1 Atrioventricular block, second degree	0.754	0.246
I44.6 Other and unspecified fascicular block	0.754	0.246
I20 Angina pectoris	0.754	0.246
T79-T79 Certain early complications of trauma	0.752	0.248
K35.0 Acute appendicitis with generalised peritonitis	0.752	0.248
K86 Other diseases of pancreas	0.751	0.249
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.749	0.251
I35.8 Other aortic valve disorders	0.746	0.254
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.746	0.254
D70-D77 Other diseases of blood and blood-forming organs	0.745	0.255
D55-D59 Haemolytic anaemias	0.745	0.255
G37 Other demyelinating diseases of central nervous system	0.744	0.256
T90 Sequelae of injuries of head	0.744	0.256
J11 Influenza, virus not identified	0.740	0.260
T80 Complications following infusion, transfusion and therapeutic injection	0.738	0.261
I51.8 Other ill-defined heart diseases	0.736	0.264
J80 Adult respiratory distress syndrome	0.736	0.264
I33 Acute and subacute endocarditis	0.734	0.266
F31 Bipolar affective disorder	0.734	0.266
E20-E35 Disorders of other endocrine glands	0.732	0.268
D86.9 Sarcoidosis, unspecified	0.730	0.270
D50-D53 Nutritional anaemias	0.730	0.270
G30-G32 Other degenerative diseases of the nervous system	0.730	0.270
K80.8 Other cholelithiasis	0.727	0.273
T15-T19 Effects of foreign body entering through natural orifice	0.724	0.275
U80.8 Agent resistant to other penicillin-related antibiotic	0.724	0.276
X58-X59 Accidental exposure to other and unspecified factors	0.722	0.277
I08 Multiple valve diseases	0.721	0.279
Y60-Y69 Misadventures to patients during surgical and medical care	0.720	0.280
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.720	0.280
H66 Suppurative and unspecified otitis media	0.718	0.282
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.718	0.282
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
J15 Bacterial pneumonia, not elsewhere classified	0.716	0.283
I00-I02 Acute rheumatic fever	0.716	0.284
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.715	0.285
F23.9 Acute and transient psychotic disorder, unspecified	0.714	0.286
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.714	0.286
T33-T35 Frostbite	0.713	0.287
T26-T28 Burns and corrosions confined to eye and internal organs	0.713	0.287
T20-T25 Burns and corrosions of external body surface, specified by site	0.713	0.287
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.713	0.287
T00-T07 Injuries involving multiple body regions	0.713	0.287
S10-S19 Injuries to the neck	0.713	0.287
I52 Other heart disorders in diseases classified elsewhere	0.713	0.287
I48 Atrial fibrillation and flutter	0.713	0.287
I43 Cardiomyopathy in diseases classified elsewhere	0.713	0.287
I41 Myocarditis in diseases classified elsewhere	0.713	0.287
I40 Acute myocarditis	0.713	0.287
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.713	0.287
I37 Pulmonary valve disorders	0.713	0.287
I32 Pericarditis in diseases classified elsewhere	0.713	0.287
F99-F99 Unspecified mental disorder	0.713	0.287
U80.1 Methicillin resistant agent	0.711	0.289
I44.2 Atrioventricular block, complete	0.711	0.289
S05 Injury of eye and orbit	0.710	0.290
I15 Secondary hypertension	0.708	0.292
I13 Hypertensive heart and renal disease	0.708	0.292
I11 Hypertensive heart disease	0.708	0.292
G00-G09 Inflammatory diseases of the central nervous system	0.708	0.292
F33 Recurrent depressive disorder	0.708	0.292
I30.1 Infective pericarditis	0.706	0.294
T87 Complications peculiar to reattachment and amputation	0.704	0.296
T86 Failure and rejection of transplanted organs and tissues	0.704	0.296
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.703	0.297
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.702	0.298
K80.3 Calculus of bile duct with cholangitis	0.701	0.299
I46 Cardiac arrest	0.701	0.299
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.700	0.300
I34.8 Other nonrheumatic mitral valve disorders	0.700	0.300
I34.2 Nonrheumatic mitral (valve) stenosis	0.700	0.300
S50-S59 Injuries to the elbow and forearm	0.697	0.303
S06.6 Traumatic subarachnoid haemorrhage	0.696	0.304
S00 Superficial injury of head	0.696	0.304
A30-A49 Other bacterial diseases	0.695	0.305
I51.6 Cardiovascular disease, unspecified	0.694	0.306
I51.5 Myocardial degeneration	0.694	0.306
I51.3 Intracardiac thrombosis, not elsewhere classified	0.694	0.306
I51.2 Rupture of papillary muscle, not elsewhere classified	0.694	0.306
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.694	0.306
I51.0 Cardiac septal defect, acquired	0.694	0.306
T31.0 Burns involving less than 10% of body surface	0.693	0.307
G35 Multiple sclerosis	0.692	0.308
S02.3 Fracture of orbital floor	0.692	0.308
J14 Pneumonia due to Haemophilus influenzae	0.691	0.309
S02.1 Fracture of base of skull	0.690	0.310
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.690	0.310
D68 Other coagulation defects	0.690	0.310
F00-F09 Organic, including symptomatic, mental disorders	0.689	0.310
F30.0 Hypomania	0.689	0.311
T81.9 Unspecified complication of procedure	0.688	0.312
T81.7 Vascular complications following a procedure, not elsewhere classified	0.688	0.312
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.688	0.312
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.688	0.312
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.686	0.314
K66 Other disorders of peritoneum	0.685	0.315
H69 Other disorders of Eustachian tube	0.685	0.315
S06.2 Diffuse brain injury	0.685	0.315
E83 Disorders of mineral metabolism	0.684	0.316
G43 Migraine	0.684	0.316
S06.4 Epidural haemorrhage	0.683	0.317
I22 Subsequent myocardial infarction	0.683	0.317
I05 Rheumatic mitral valve diseases	0.682	0.318
H72 Perforation of tympanic membrane	0.681	0.318
V10-V19 Pedal cyclist injured in transport accident	0.681	0.319
K85 Acute pancreatitis	0.681	0.319
H73 Other disorders of tympanic membrane	0.681	0.319
S06.5 Traumatic subdural haemorrhage	0.680	0.320
T82.1 Mechanical complication of cardiac electronic device	0.680	0.320
I20.1 Angina pectoris with documented spasm	0.679	0.321
I12 Hypertensive renal disease	0.679	0.321
T93 Sequelae of injuries of lower limb	0.678	0.322
I30.9 Acute pericarditis, unspecified	0.678	0.322
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.677	0.323
F70-F79 Mental retardation	0.677	0.323
F25 Schizoaffective disorders	0.674	0.325
K80.2 Calculus of gallbladder without cholecystitis	0.674	0.326
I44.5 Left posterior fascicular block	0.673	0.326
I44.4 Left anterior fascicular block	0.673	0.326
Y84.6 Urinary catheterisation	0.673	0.327
S08 Traumatic amputation of part of head	0.673	0.327
S07 Crushing injury of head	0.673	0.327
S04 Injury of cranial nerves	0.673	0.327
S03 Dislocation, sprain and strain of joints and ligaments of head	0.673	0.327
I44.3 Other and unspecified atrioventricular block	0.672	0.328
W50-W64 Exposure to animate mechanical forces	0.672	0.328
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.671	0.329
J17 Pneumonia in diseases classified elsewhere	0.671	0.329
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.671	0.329
J12 Viral pneumonia, not elsewhere classified	0.671	0.329
J09 Influenza due to certain identified influenza virus	0.671	0.329
K82.8 Other specified diseases of gallbladder	0.670	0.330
H65.9 Nonsuppurative otitis media, unspecified	0.669	0.331
T83.3 Mechanical complication of intra-uterine contraceptive device	0.669	0.331
I20.9 Angina pectoris, unspecified	0.667	0.333
K82.1 Hydrops of gallbladder	0.667	0.333
S80-S89 Injuries to the knee and lower leg	0.665	0.335
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.665	0.335
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.664	0.336
K38 Other diseases of appendix	0.663	0.337
I77 Other disorders of arteries and arterioles	0.663	0.337
J82 Pulmonary eosinophilia, not elsewhere classified	0.660	0.340
K83 Other diseases of biliary tract	0.658	0.342
F80-F89 Disorders of psychological development	0.658	0.342
J21 Acute bronchiolitis	0.657	0.343
J20 Acute bronchitis	0.657	0.343
T88 Other complications of surgical and medical care, not elsewhere classified	0.657	0.343
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.657	0.343
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.656	0.344
J10 Influenza due to identified influenza virus	0.655	0.345
D75 Other diseases of blood and blood-forming organs	0.655	0.345
S02.6 Fracture of mandible	0.654	0.346
K36 Other appendicitis	0.653	0.347
S02.0 Fracture of vault of skull	0.652	0.348
F60-F69 Disorders of adult personality and behaviour	0.651	0.348
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.651	0.349
T91 Sequelae of injuries of neck and trunk	0.650	0.350
S40 Superficial injury of shoulder and upper arm	0.650	0.350
J18.8 Other pneumonia, organism unspecified	0.648	0.352
J18.2 Hypostatic pneumonia, unspecified	0.648	0.352
G40.9 Epilepsy, unspecified	0.648	0.352
J84.1 Other interstitial pulmonary diseases with fibrosis	0.648	0.352
F32 Depressive episode	0.647	0.353
H65.3 Chronic mucoid otitis media	0.647	0.353
Y35-Y36 Legal intervention and operations of war	0.645	0.355
Y10-Y34 Event of undetermined intent	0.645	0.355
Y00-Y09 Assault	0.645	0.355
X85-X99 Assault	0.645	0.355
X50-X57 Overexertion, travel and privation	0.645	0.355
X30-X39 Exposure to forces of nature	0.645	0.355
X20-X29 Contact with venomous animals and plants	0.645	0.355
X10-X19 Contact with heat and hot substances	0.645	0.355
X00-X09 Exposure to smoke, fire and flames	0.645	0.355
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.645	0.355
W75-W84 Other accidental threats to breathing	0.645	0.355
W65-W74 Accidental drowning and submersion	0.645	0.355
V98-V99 Other and unspecified transport accidents	0.645	0.355
V95-V97 Air and space transport accidents	0.645	0.355
V90-V94 Water transport accidents	0.645	0.355
V80-V89 Other land transport accidents	0.645	0.355
V70-V79 Bus occupant injured in transport accident	0.645	0.355
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.645	0.355
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.645	0.355
V40-V49 Car occupant injured in transport accident	0.645	0.355
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.645	0.355
V01-V09 Pedestrian injured in transport accident	0.645	0.355
F22 Persistent delusional disorders	0.644	0.356
F28 Other nonorganic psychotic disorders	0.644	0.356
F24 Induced delusional disorder	0.644	0.356
F21 Schizotypal disorder	0.644	0.356
G44 Other headache syndromes	0.644	0.356
J60-J70 Lung diseases due to external agents	0.644	0.356
G37.9 Demyelinating disease of central nervous system, unspecified	0.643	0.357
H74 Other disorders of middle ear and mastoid	0.643	0.357
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.642	0.357
G40.5 Special epileptic syndromes	0.642	0.357
S02.8 Fractures of other skull and facial bones	0.642	0.358
U51 Admission status on psychiatric patients	0.642	0.358
X40-X49 Accidental poisoning by and exposure to noxious substances	0.641	0.359
G82 Paraplegia and tetraplegia	0.640	0.359
I21 Acute myocardial infarction	0.640	0.360
I23 Certain current complications following acute myocardial infarction	0.639	0.361
F38 Other mood [affective] disorders	0.636	0.364
F34 Persistent mood [affective] disorders	0.636	0.364
F39 Unspecified mood [affective] disorder	0.636	0.364
Q80-Q89 Other congenital malformations	0.635	0.365
D51 Vitamin B12 deficiency anaemia	0.635	0.365
X60-X84 Intentional self-harm	0.634	0.366
K81.8 Other cholecystitis	0.633	0.367
S02.5 Fracture of tooth	0.632	0.368
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.632	0.368
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.632	0.368
S01 Open wound of head	0.631	0.369
J84.9 Interstitial pulmonary disease, unspecified	0.631	0.369
Chapter XV Pregnancy, childbirth and the puerperium	0.630	0.370
D69 Purpura and other haemorrhagic conditions	0.630	0.370
K35.2 Acute appendicitis with generalized peritonitis	0.629	0.370
K35.1 Acute appendicitis with peritoneal abscess	0.629	0.370
K90-K93 Other diseases of the digestive system	0.629	0.371
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.628	0.371
T85.2 Mechanical complication of intraocular lens	0.628	0.372
F30.9 Manic episode, unspecified	0.627	0.373
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.624	0.376
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.624	0.376
H70 Mastoiditis and related conditions	0.624	0.376
H68 Eustachian salpingitis and obstruction	0.624	0.376
H67 Otitis media in diseases classified elsewhere	0.624	0.376
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.624	0.376
S06.0 Concussion	0.623	0.377
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.622	0.378
T98 Sequelae of other and unspecified effects of external causes	0.622	0.378
T95 Sequelae of burns, corrosions and frostbite	0.622	0.378
T94 Sequelae of injuries involving multiple and unspecified body regions	0.622	0.378
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.622	0.378
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.622	0.378
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.622	0.378
I24.9 Acute ischaemic heart disease, unspecified	0.621	0.378
I08.0 Disorders of both mitral and aortic valves	0.621	0.379
S02.2 Fracture of nasal bones	0.620	0.380
F31.9 Bipolar affective disorder, unspecified	0.620	0.380
G81 Hemiplegia	0.619	0.380
H90-H95 Other disorders of ear	0.619	0.381
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.618	0.382
T32 Corrosions classified according to extent of body surface involved	0.616	0.384
T30 Burn and corrosion, body region unspecified	0.616	0.384
T29 Burns and corrosions of multiple body regions	0.616	0.384
V20-V29 Motorcycle rider injured in transport accident	0.616	0.384
S06.9 Intracranial injury, unspecified	0.615	0.385
S06.8 Other intracranial injuries	0.615	0.385
S06.7 Intracranial injury with prolonged coma	0.615	0.385
S06.3 Focal brain injury	0.615	0.385
S06.1 Traumatic cerebral oedema	0.615	0.385
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.614	0.386
B99-B99 Other infectious diseases	0.614	0.386
U81 Agent resistant to vancomycin and related antibiotics	0.614	0.386
U50 Level of care administered to neonates	0.614	0.386
U07 Emergency use of U07	0.614	0.386
U06 Emergency use of U06	0.614	0.386
U04 Severe acute respiratory syndrome [SARS]	0.614	0.386
U52 First in a series of a regular day/night admissions	0.614	0.386
E40-E46 Malnutrition	0.613	0.387
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.613	0.387
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.613	0.387
T82.4 Mechanical complication of vascular dialysis catheter	0.613	0.387
T82.3 Mechanical complication of other vascular grafts	0.613	0.387
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.613	0.387
T82.0 Mechanical complication of heart valve prosthesis	0.613	0.387
I95-I99 Other and unspecified disorders of the circulatory system	0.613	0.387
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.611	0.389
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.610	0.390
I30.8 Other forms of acute pericarditis	0.609	0.391
I30.0 Acute nonspecific idiopathic pericarditis	0.609	0.391
S02.9 Fracture of skull and facial bones, part unspecified	0.609	0.391
S02.7 Multiple fractures involving skull and facial bones	0.609	0.391
Y83.6 Removal of other organ (partial) (total)	0.609	0.391
K86.8 Other specified diseases of pancreas	0.608	0.392
S42 Fracture of shoulder and upper arm	0.608	0.392
D84 Other immunodeficiencies	0.608	0.392
D83 Common variable immunodeficiency	0.608	0.392
D82 Immunodeficiency associated with other major defects	0.608	0.392
D81 Combined immunodeficiencies	0.608	0.392
D80 Immunodeficiency with predominantly antibody defects	0.608	0.392
Y84.0 Cardiac catheterisation	0.607	0.393
D72 Other disorders of white blood cells	0.606	0.393
S00.1 Contusion of eyelid and periocular area	0.606	0.394
G70-G73 Diseases of myoneural junction and muscle	0.606	0.394
D86.0 Sarcoidosis of lung	0.605	0.395
S30 Superficial injury of abdomen, lower back and pelvis	0.603	0.397
T92 Sequelae of injuries of upper limb	0.602	0.397
D60-D64 Aplastic and other anaemias	0.602	0.398
K35.3 Acute appendicitis with localized peritonitis	0.600	0.399
I09 Other rheumatic heart diseases	0.600	0.400
I06 Rheumatic aortic valve diseases	0.600	0.400
J11.1 Influenza with other respiratory manifestations, virus not identified	0.600	0.400
I71 Aortic aneurysm and dissection	0.600	0.400
K70-K77 Diseases of liver	0.600	0.400
F20 Schizophrenia	0.600	0.400
W00-W19 Falls	0.599	0.401
J18.1 Lobar pneumonia, unspecified	0.598	0.402
G36 Other acute disseminated demyelination	0.598	0.402
T90.2 Sequelae of fracture of skull and facial bones	0.597	0.403
H60-H62 Diseases of external ear	0.596	0.403
B65-B83 Helminthiases	0.596	0.404
D59 Acquired haemolytic anaemia	0.596	0.404
I60-I69 Cerebrovascular diseases	0.596	0.404
X59 Exposure to unspecified factor	0.595	0.404
S92 Fracture of foot, except ankle	0.595	0.405
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.593	0.406
A49 Bacterial infection of unspecified site	0.593	0.406
I24.1 Dressler's syndrome	0.593	0.407
E21.0 Primary hyperparathyroidism	0.593	0.407
D75.2 Essential thrombocytosis	0.592	0.408
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.592	0.408
T90.9 Sequelae of unspecified injury of head	0.591	0.409
K82.9 Disease of gallbladder, unspecified	0.590	0.410
K82.3 Fistula of gallbladder	0.590	0.410
K82.2 Perforation of gallbladder	0.590	0.410
K82.0 Obstruction of gallbladder	0.590	0.410
E83.5 Disorders of calcium metabolism	0.589	0.411
J00-J06 Acute upper respiratory infections	0.589	0.411
T66-T78 Other and unspecified effects of external causes	0.588	0.412
S70-S79 Injuries to the hip and thigh	0.588	0.412
H71 Cholesteatoma of middle ear	0.586	0.414
K86.0 Alcohol-induced chronic pancreatitis	0.586	0.414
F32.3 Severe depressive episode with psychotic symptoms	0.585	0.415
S20-S29 Injuries to the thorax	0.585	0.415
G80 Infantile cerebral palsy	0.585	0.415
S49 Other and unspecified injuries of shoulder and upper arm	0.584	0.415
S48 Traumatic amputation of shoulder and upper arm	0.584	0.415
S46 Injury of muscle and tendon at shoulder and upper arm level	0.584	0.415
S45 Injury of blood vessels at shoulder and upper arm level	0.584	0.415
S44 Injury of nerves at shoulder and upper arm level	0.584	0.415
S41 Open wound of shoulder and upper arm	0.584	0.415
S47 Crushing injury of shoulder and upper arm	0.584	0.415
D67 Hereditary factor IX deficiency	0.583	0.416
D66 Hereditary factor VIII deficiency	0.583	0.416
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.583	0.416
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.582	0.418
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.582	0.418
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.582	0.418
T83.2 Mechanical complication of graft of urinary organ	0.582	0.418
T83.1 Mechanical complication of other urinary devices and implants	0.582	0.418
I70 Atherosclerosis	0.581	0.419
E85 Amyloidosis	0.581	0.419
E84 Cystic fibrosis	0.581	0.419
E79 Disorders of purine and pyrimidine metabolism	0.581	0.419
E77 Disorders of glycoprotein metabolism	0.581	0.419
E76 Disorders of glycosaminoglycan metabolism	0.581	0.419
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.581	0.419
E74 Other disorders of carbohydrate metabolism	0.581	0.419
E73 Lactose intolerance	0.581	0.419
E72 Other disorders of amino-acid metabolism	0.581	0.419
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.581	0.419
E70 Disorders of aromatic amino-acid metabolism	0.581	0.419
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.581	0.419
G46 Vascular syndromes of brain in cerebrovascular diseases	0.580	0.419
G41 Status epilepticus	0.580	0.419
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.580	0.420
E78.8 Other disorders of lipoprotein metabolism	0.580	0.420
E78.6 Lipoprotein deficiency	0.580	0.420
E78.4 Other hyperlipidaemia	0.580	0.420
E78.3 Hyperchylomicronaemia	0.580	0.420
E78.2 Mixed hyperlipidaemia	0.580	0.420
E78.1 Pure hyperglyceridaemia	0.580	0.420
H65.4 Other chronic nonsuppurative otitis media	0.580	0.420
S02.30 Fracture of orbital floor (closed)	0.579	0.421
U80.0 Penicillin resistant agent	0.579	0.421
B95-B98 Bacterial, viral and other infectious agents	0.579	0.421
T79 Certain early complications of trauma, not elsewhere classified	0.578	0.421
K66.0 Peritoneal adhesions	0.578	0.422
I35.2 Aortic (valve) stenosis with insufficiency	0.578	0.422
F33.1 Recurrent depressive disorder, current episode moderate	0.578	0.422
Y83.8 Other surgical procedures	0.577	0.423
S02.10 Fracture of base of skull (closed)	0.576	0.424
Q60-Q64 Congenital malformations of the urinary system	0.576	0.424
S32 Fracture of lumbar spine and pelvis	0.575	0.425
J13 Pneumonia due to Streptococcus pneumoniae	0.575	0.425
Q50-Q56 Congenital malformations of genital organs	0.575	0.425
T83.0 Mechanical complication of urinary (indwelling) catheter	0.575	0.425
S82 Fracture of lower leg, including ankle	0.575	0.425
E28 Ovarian dysfunction	0.574	0.426
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.573	0.427
S91 Open wound of ankle and foot	0.573	0.427
D73 Diseases of spleen	0.573	0.427
E80 Disorders of porphyrin and bilirubin metabolism	0.573	0.427
I21.9 Acute myocardial infarction, unspecified	0.572	0.428
H66.3 Other chronic suppurative otitis media	0.572	0.428
G43.1 Migraine with aura [classical migraine]	0.570	0.430
K82.4 Cholesterolosis of gallbladder	0.570	0.430
B90-B94 Sequelae of infectious and parasitic diseases	0.569	0.430
B85-B89 Pediculosis, acariasis and other infestations	0.569	0.430
B50-B64 Protozoal diseases	0.569	0.430
B20-B24 Human immunodeficiency virus [HIV] disease	0.569	0.430
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.569	0.430
A80-A89 Viral infections of the central nervous system	0.569	0.430
A75-A79 Rickettsioses	0.569	0.430
A70-A74 Other diseases caused by chlamydiae	0.569	0.430
A65-A69 Other spirochaetal diseases	0.569	0.430
A20-A28 Certain zoonotic bacterial diseases	0.569	0.430
A15-A19 Tuberculosis	0.569	0.430
T90.4 Sequelae of injury of eye and orbit	0.569	0.431
F23.8 Other acute and transient psychotic disorders	0.567	0.433
F23.3 Other acute predominantly delusional psychotic disorders	0.567	0.433
F23.2 Acute schizophrenia-like psychotic disorder	0.567	0.433
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.567	0.433
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.567	0.433
S00.2 Other superficial injuries of eyelid and periocular area	0.567	0.433

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations