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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs138812
log Bayes Factor = 5.52275
Chromosome 22   position 50,160,983  (GRCh37) Explore rs138812 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
1.000 0.000 0.000
T39.1 4-Aminophenol derivatives
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
H65-H75 Diseases of middle ear and mastoid
0.996 0.004 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
# Top node
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
Chapter IX Diseases of the circulatory system
0.984 0.016 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.984 0.016 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.984 0.016 0.000
I95 Hypotension
0.983 0.017 0.000
S70-S79 Injuries to the hip and thigh
0.979 0.021 0.000
H73 Other disorders of tympanic membrane
0.979 0.021 0.000
I95.9 Hypotension, unspecified
0.979 0.021 0.000
H73.8 Other specified disorders of tympanic membrane
0.968 0.032 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.961 0.039 0.000
I60-I69 Cerebrovascular diseases
0.952 0.048 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.952 0.048 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.951 0.049 0.000
S72 Fracture of femur
0.950 0.050 0.000
H74 Other disorders of middle ear and mastoid
0.948 0.052 0.000
Chapter VI Diseases of the nervous system
0.944 0.056 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.942 0.058 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.938 0.062 0.000
S72.0 Fracture of neck of femur
0.937 0.063 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.937 0.063 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.931 0.069 0.000
S72.00 Fracture of neck of femur (closed)
0.928 0.072 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.921 0.079 0.000
T51 Toxic effect of alcohol
0.916 0.084 0.000
H66 Suppurative and unspecified otitis media
0.908 0.092 0.000
Y95 Nosocomial condition
0.906 0.094 0.000
G40-G47 Episodic and paroxysmal disorders
0.901 0.099 0.000
T43.2 Other and unspecified antidepressants
0.899 0.101 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.896 0.104 0.000
T40.2 Other opioids
0.891 0.109 0.000
H71 Cholesteatoma of middle ear
0.891 0.109 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.884 0.116 0.000
T39.0 Salicylates
0.872 0.128 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.872 0.128 0.000
T42.4 Benzodiazepines
0.870 0.130 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.868 0.132 0.000
G90-G99 Other disorders of the nervous system
0.868 0.132 0.000
Chapter V Mental and behavioural disorders
0.865 0.135 0.000
S70 Superficial injury of hip and thigh
0.862 0.138 0.000
T51.9 Alcohol, unspecified
0.860 0.140 0.000
S10-S19 Injuries to the neck
0.859 0.140 0.000
H65 Nonsuppurative otitis media
0.859 0.141 0.000
H90-H95 Other disorders of ear
0.853 0.147 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.850 0.149 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.840 0.160 0.000
I05-I09 Chronic rheumatic heart diseases
0.840 0.160 0.000
I95.1 Orthostatic hypotension
0.839 0.161 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.838 0.162 0.000
Chapter XXII Codes for special purposes
0.835 0.165 0.000
I95.2 Hypotension due to drugs
0.831 0.169 0.000
I60 Subarachnoid haemorrhage
0.829 0.171 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.823 0.177 0.000
G44 Other headache syndromes
0.821 0.179 0.000
X50-X57 Overexertion, travel and privation
0.816 0.184 0.000
H80-H83 Diseases of inner ear
0.814 0.186 0.000
H74.1 Adhesive middle ear disease
0.812 0.188 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.810 0.190 0.000
T91 Sequelae of injuries of neck and trunk
0.810 0.190 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.803 0.197 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.803 0.197 0.000
T51.0 Ethanol
0.802 0.198 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.800 0.200 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.797 0.203 0.000
V80-V89 Other land transport accidents
0.796 0.204 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.794 0.206 0.000
H66.9 Otitis media, unspecified
0.791 0.209 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.790 0.210 0.000
I69 Sequelae of cerebrovascular disease
0.785 0.215 0.000
G70-G73 Diseases of myoneural junction and muscle
0.783 0.217 0.000
G40 Epilepsy
0.782 0.218 0.000
G43 Migraine
0.776 0.224 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.772 0.228 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.772 0.228 0.000
I05 Rheumatic mitral valve diseases
0.771 0.229 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.769 0.231 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.768 0.232 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.767 0.233 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.766 0.233 0.000
E20-E35 Disorders of other endocrine glands
0.764 0.236 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.763 0.237 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.763 0.237 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.761 0.239 0.000
H70 Mastoiditis and related conditions
0.760 0.240 0.000
H65.4 Other chronic nonsuppurative otitis media
0.759 0.241 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.759 0.241 0.000
H65.3 Chronic mucoid otitis media
0.759 0.241 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.757 0.243 0.000
T42.1 Iminostilbenes
0.752 0.248 0.000
S79 Other and unspecified injuries of hip and thigh
0.749 0.251 0.000
I61 Intracerebral haemorrhage
0.748 0.252 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.748 0.252 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.748 0.252 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.747 0.253 0.000
I95.0 Idiopathic hypotension
0.746 0.253 0.000
X60-X84 Intentional self-harm
0.746 0.254 0.000
H60-H62 Diseases of external ear
0.744 0.256 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.743 0.257 0.000
W50-W64 Exposure to animate mechanical forces
0.743 0.257 0.000
Y60.0 During surgical operation
0.743 0.257 0.000
V98-V99 Other and unspecified transport accidents
0.739 0.261 0.000
I09 Other rheumatic heart diseases
0.738 0.262 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.736 0.264 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.736 0.264 0.000
T59 Toxic effect of other gases, fumes and vapours
0.735 0.264 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.734 0.266 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.733 0.266 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.732 0.268 0.000
G90 Disorders of autonomic nervous system
0.731 0.269 0.000
T40.6 Other and unspecified narcotics
0.731 0.269 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.730 0.270 0.000
H81 Disorders of vestibular function
0.730 0.270 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.729 0.271 0.000
F30-F39 Mood [affective] disorders
0.728 0.272 0.000
I99 Other and unspecified disorders of circulatory system
0.728 0.272 0.000
V01-V09 Pedestrian injured in transport accident
0.727 0.273 0.000
G91 Hydrocephalus
0.727 0.273 0.000
E00-E07 Disorders of thyroid gland
0.726 0.274 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.726 0.274 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.725 0.275 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.722 0.278 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.721 0.279 0.000
G44.2 Tension-type headache
0.721 0.279 0.000
Y00-Y09 Assault
0.719 0.281 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.719 0.281 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.719 0.281 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
T39.4 Antirheumatics, not elsewhere classified
0.717 0.283 0.000
T39.2 Pyrazolone derivatives
0.717 0.283 0.000
H74.4 Polyp of middle ear
0.717 0.283 0.000
S72.8 Fractures of other parts of femur
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
G41 Status epilepticus
0.714 0.286 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.714 0.286 0.000
H68 Eustachian salpingitis and obstruction
0.714 0.286 0.000
H67 Otitis media in diseases classified elsewhere
0.714 0.286 0.000
G20-G26 Extrapyramidal and movement disorders
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.712 0.288 0.000
S72.9 Fracture of femur, part unspecified
0.711 0.289 0.000
H66.4 Suppurative otitis media, unspecified
0.710 0.290 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.710 0.290 0.000
Y48 Anaesthetics and therapeutic gases
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
F60-F69 Disorders of adult personality and behaviour
0.708 0.292 0.000
G30-G32 Other degenerative diseases of the nervous system
0.707 0.293 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.706 0.294 0.000
I00-I02 Acute rheumatic fever
0.706 0.294 0.000
T43.9 Psychotropic drug, unspecified
0.706 0.294 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.706 0.294 0.000
T43.6 Psychostimulants with abuse potential
0.706 0.294 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.706 0.294 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.705 0.295 0.000
T91.1 Sequelae of fracture of spine
0.704 0.296 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.297 0.000
S78 Traumatic amputation of hip and thigh
0.702 0.298 0.000
S77 Crushing injury of hip and thigh
0.702 0.298 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.702 0.298 0.000
S75 Injury of blood vessels at hip and thigh level
0.702 0.298 0.000
S74 Injury of nerves at hip and thigh level
0.702 0.298 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.702 0.298 0.000
H73.1 Chronic myringitis
0.702 0.298 0.000
H73.0 Acute myringitis
0.702 0.298 0.000
S72.2 Subtrochanteric fracture
0.700 0.300 0.000
H66.3 Other chronic suppurative otitis media
0.698 0.302 0.000
T00-T07 Injuries involving multiple body regions
0.696 0.304 0.000
E07 Other disorders of thyroid
0.695 0.305 0.000
H91 Other hearing loss
0.694 0.306 0.000
T56 Toxic effect of metals
0.693 0.307 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.692 0.308 0.000
G93 Other disorders of brain
0.692 0.308 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.691 0.309 0.000
T58 Toxic effect of carbon monoxide
0.688 0.312 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.686 0.314 0.000
I05.2 Mitral stenosis with insufficiency
0.685 0.315 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.684 0.316 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.683 0.317 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.683 0.317 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.683 0.317 0.000
H72 Perforation of tympanic membrane
0.683 0.317 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.683 0.317 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.683 0.317 0.000
T42.3 Barbiturates
0.683 0.317 0.000
T42.2 Succinimides and oxazolidinediones
0.683 0.317 0.000
T42.0 Hydantoin derivatives
0.683 0.317 0.000
T65 Toxic effect of other and unspecified substances
0.682 0.318 0.000
T62 Toxic effect of other noxious substances eaten as food
0.682 0.318 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.682 0.318 0.000
T60 Toxic effect of pesticides
0.682 0.318 0.000
T57 Toxic effect of other inorganic substances
0.682 0.318 0.000
T54 Toxic effect of corrosive substances
0.682 0.318 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.682 0.318 0.000
T52 Toxic effect of organic solvents
0.682 0.318 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.682 0.318 0.000
T55 Toxic effect of soaps and detergents
0.682 0.318 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.681 0.319 0.000
S10 Superficial injury of neck
0.681 0.319 0.000
S72.7 Multiple fractures of femur
0.681 0.319 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.675 0.325 0.000
T40.8 Lysergide [LSD]
0.675 0.325 0.000
T40.7 Cannabis (derivatives)
0.675 0.325 0.000
T40.5 Cocaine
0.675 0.325 0.000
T40.3 Methadone
0.675 0.325 0.000
T40.1 Heroin
0.675 0.325 0.000
T40.0 Opium
0.675 0.325 0.000
D80-D89 Certain disorders involving the immune mechanism
0.675 0.325 0.000
G96 Other disorders of central nervous system
0.675 0.325 0.000
Y52 Agents primarily affecting the cardiovascular system
0.675 0.325 0.000
E29 Testicular dysfunction
0.674 0.326 0.000
G44.0 Cluster headache syndrome
0.673 0.327 0.000
E07.9 Disorder of thyroid, unspecified
0.673 0.327 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.672 0.328 0.000
Y98 Lifestyle-related condition
0.672 0.328 0.000
Y97 Environmental-pollution-related condition
0.672 0.328 0.000
Y96 Work-related condition
0.672 0.328 0.000
S72.01 Fracture of neck of femur (open)
0.672 0.328 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.671 0.328 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.671 0.328 0.000
F10.1 Harmful use
0.671 0.329 0.000
H92 Otalgia and effusion of ear
0.669 0.330 0.000
S12 Fracture of neck
0.669 0.331 0.000
Y54.8 Agents affecting uric acid metabolism
0.668 0.332 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.333 0.000
Y58 Bacterial vaccines
0.667 0.333 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.333 0.000
S14 Injury of nerves and spinal cord at neck level
0.667 0.333 0.000
I27 Other pulmonary heart diseases
0.666 0.334 0.000
W94 Exposure to high and low air pressure and changes in air pressure
0.666 0.334 0.000
V20-V29 Motorcycle rider injured in transport accident
0.666 0.334 0.000
D86 Sarcoidosis
0.666 0.334 0.000
T40.4 Other synthetic narcotics
0.665 0.335 0.000
I09.9 Rheumatic heart disease, unspecified
0.664 0.336 0.000
S19 Other and unspecified injuries of neck
0.664 0.336 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.663 0.337 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.663 0.337 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.662 0.338 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.661 0.339 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.659 0.341 0.000
W00-W19 Falls
0.658 0.342 0.000
H90 Conductive and sensorineural hearing loss
0.658 0.342 0.000
X51 Travel and motion
0.658 0.342 0.000
T51.8 Other alcohols
0.657 0.343 0.000
T51.3 Fusel oil
0.657 0.343 0.000
T51.2 2-Propanol
0.657 0.343 0.000
T51.1 Methanol
0.657 0.343 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.654 0.346 0.000
T66-T78 Other and unspecified effects of external causes
0.654 0.346 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.651 0.349 0.000
H66.0 Acute suppurative otitis media
0.651 0.349 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.650 0.349 0.000
T98 Sequelae of other and unspecified effects of external causes
0.650 0.350 0.000
H81.1 Benign paroxysmal vertigo
0.650 0.350 0.000
S20-S29 Injuries to the thorax
0.649 0.351 0.000
D86.9 Sarcoidosis, unspecified
0.648 0.352 0.000
F33 Recurrent depressive disorder
0.648 0.352 0.000
I95.8 Other hypotension
0.647 0.352 0.000
V40-V49 Car occupant injured in transport accident
0.647 0.353 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.647 0.353 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.646 0.354 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.645 0.355 0.000
G43.9 Migraine, unspecified
0.644 0.356 0.000
U88 Agent resistant to multiple antibiotics
0.644 0.356 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.643 0.357 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.643 0.357 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.643 0.357 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.643 0.357 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.643 0.357 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.643 0.357 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.643 0.357 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.643 0.357 0.000
Y51.0 Anticholinesterase agents
0.643 0.357 0.000
I62 Other nontraumatic intracranial haemorrhage
0.640 0.359 0.000
Y54.3 Benzothiadiazine derivatives
0.640 0.359 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.640 0.360 0.000
Y47.1 Benzodiazepines
0.640 0.360 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.638 0.361 0.000
E27 Other disorders of adrenal gland
0.638 0.362 0.000
S40-S49 Injuries to the shoulder and upper arm
0.636 0.364 0.000
X50 Overexertion and strenuous or repetitive movements
0.636 0.364 0.000
F99-F99 Unspecified mental disorder
0.635 0.365 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.635 0.365 0.000
S70.1 Contusion of thigh
0.634 0.366 0.000
Y65 Other misadventures during surgical and medical care
0.634 0.366 0.000
Y64 Contaminated medical or biological substances
0.634 0.366 0.000
Y63 Failure in dosage during surgical and medical care
0.634 0.366 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.634 0.366 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.634 0.366 0.000
Y69 Unspecified misadventure during surgical and medical care
0.634 0.366 0.000
Y66 Nonadministration of surgical and medical care
0.634 0.366 0.000
E04 Other non-toxic goitre
0.634 0.366 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.632 0.368 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.632 0.368 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.632 0.368 0.000
S72.3 Fracture of shaft of femur
0.631 0.368 0.000
S71 Open wound of hip and thigh
0.631 0.369 0.000
I05.0 Mitral stenosis
0.631 0.369 0.000
I69.3 Sequelae of cerebral infarction
0.630 0.369 0.000
G82 Paraplegia and tetraplegia
0.630 0.370 0.000
G90.3 Multisystem degeneration
0.630 0.370 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.630 0.370 0.000
Y53.4 Other laxatives
0.629 0.371 0.000
Y60.4 During endoscopic examination
0.629 0.371 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.628 0.372 0.000
G71 Primary disorders of muscles
0.628 0.372 0.000
S70.0 Contusion of hip
0.623 0.376 0.000
T63 Toxic effect of contact with venomous animals
0.623 0.377 0.000
T95 Sequelae of burns, corrosions and frostbite
0.622 0.378 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.622 0.378 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.622 0.378 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.622 0.378 0.000
G92 Toxic encephalopathy
0.622 0.378 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.621 0.379 0.000
S72.4 Fracture of lower end of femur
0.620 0.379 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.621 0.379 0.000
F70-F79 Mental retardation
0.621 0.379 0.000
T93 Sequelae of injuries of lower limb
0.620 0.380 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.619 0.381 0.000
X45 Accidental poisoning by and exposure to alcohol
0.618 0.381 0.000
F80-F89 Disorders of psychological development
0.618 0.382 0.000
G93.8 Other specified disorders of brain
0.618 0.382 0.000
S70.8 Other superficial injuries of hip and thigh
0.618 0.382 0.000
S70.7 Multiple superficial injuries of hip and thigh
0.618 0.382 0.000
S17 Crushing injury of neck
0.616 0.384 0.000
S15 Injury of blood vessels at neck level
0.616 0.384 0.000
S11 Open wound of neck
0.616 0.384 0.000
S18 Traumatic amputation at neck level
0.616 0.384 0.000
S16 Injury of muscle and tendon at neck level
0.616 0.384 0.000
H65.1 Other acute nonsuppurative otitis media
0.616 0.384 0.000
H65.0 Acute serous otitis media
0.616 0.384 0.000
T91.3 Sequelae of injury of spinal cord
0.616 0.384 0.000
H60 Otitis externa
0.615 0.385 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.613 0.387 0.000
I27.8 Other specified pulmonary heart diseases
0.613 0.387 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.612 0.388 0.000
E04.9 Non-toxic goitre, unspecified
0.612 0.388 0.000
E16 Other disorders of pancreatic internal secretion
0.611 0.389 0.000
G25 Other extrapyramidal and movement disorders
0.611 0.389 0.000
E29.1 Testicular hypofunction
0.610 0.390 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.610 0.390 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.610 0.390 0.000
T47.7 Emetics
0.610 0.390 0.000
T47.6 Antidiarrhoeal drugs
0.610 0.390 0.000
T47.5 Digestants
0.610 0.390 0.000
T47.4 Other laxatives
0.610 0.390 0.000
T47.3 Saline and osmotic laxatives
0.610 0.390 0.000
T47.2 Stimulant laxatives
0.610 0.390 0.000
T47.0 Histamine H(2)-receptor antagonists
0.610 0.390 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.608 0.392 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.608 0.392 0.000
E28 Ovarian dysfunction
0.607 0.393 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.606 0.394 0.000
G93.6 Cerebral oedema
0.606 0.394 0.000
F10.4 Withdrawal state with delirium
0.605 0.395 0.000
I05.9 Mitral valve disease, unspecified
0.605 0.395 0.000
V10-V19 Pedal cyclist injured in transport accident
0.604 0.396 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.604 0.396 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.602 0.397 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.602 0.397 0.000
T46.7 Peripheral vasodilators
0.602 0.397 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.602 0.397 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.602 0.397 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.602 0.397 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.602 0.397 0.000
E26 Hyperaldosteronism
0.602 0.398 0.000
I06 Rheumatic aortic valve diseases
0.602 0.398 0.000
G43.1 Migraine with aura [classical migraine]
0.602 0.398 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.602 0.398 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.602 0.398 0.000
H81.2 Vestibular neuronitis
0.601 0.399 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.601 0.399 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.601 0.399 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.601 0.399 0.000
I98.0 Cardiovascular syphilis
0.601 0.399 0.000
S31 Open wound of abdomen, lower back and pelvis
0.601 0.399 0.000
G44.8 Other specified headache syndromes
0.600 0.400 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.599 0.400 0.000
T79-T79 Certain early complications of trauma
0.599 0.401 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.598 0.402 0.000
G95 Other diseases of spinal cord
0.597 0.403 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.597 0.403 0.000
T46.1 Calcium-channel blockers
0.596 0.403 0.000
G72 Other myopathies
0.596 0.404 0.000
T90 Sequelae of injuries of head
0.596 0.404 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.595 0.405 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.595 0.405 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.595 0.405 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.595 0.405 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.595 0.405 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.594 0.406 0.000
T45.0 Antiallergic and antiemetic drugs
0.594 0.406 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.590 0.409 0.000
H70.9 Mastoiditis, unspecified
0.590 0.409 0.000
X48 Accidental poisoning by and exposure to pesticides
0.590 0.410 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.590 0.410 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.590 0.410 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.590 0.410 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.590 0.410 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.590 0.410 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.590 0.410 0.000
G43.0 Migraine without aura [common migraine]
0.590 0.410 0.000
X41.9 Unspecified place
0.589 0.411 0.000
G44.3 Chronic posttraumatic headache
0.589 0.411 0.000
G44.1 Vascular headache, not elsewhere classified
0.589 0.411 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.587 0.413 0.000
S90-S99 Injuries to the ankle and foot
0.587 0.413 0.000
G70 Myasthenia gravis and other myoneural disorders
0.586 0.414 0.000
Y44 Agents primarily affecting blood constituents
0.586 0.414 0.000
X57 Unspecified privation
0.585 0.415 0.000
X54 Lack of water
0.585 0.415 0.000
X53 Lack of food
0.585 0.415 0.000
X52 Prolonged stay in weightless environment
0.585 0.415 0.000
H69 Other disorders of Eustachian tube
0.584 0.415 0.000
S79.9 Unspecified injury of hip and thigh
0.584 0.415 0.000
H91.8 Other specified hearing loss
0.584 0.416 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.584 0.416 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.582 0.418 0.000
H65.2 Chronic serous otitis media
0.581 0.418 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.581 0.419 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.581 0.419 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.581 0.419 0.000
T59.8 Other specified gases, fumes and vapours
0.581 0.419 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.581 0.419 0.000
Y60.9 During unspecified surgical and medical care
0.581 0.419 0.000
Y60.8 During other surgical and medical care
0.581 0.419 0.000
Y60.7 During administration of enema
0.581 0.419 0.000
Y60.6 During aspiration, puncture and other catheterisation
0.581 0.419 0.000
Y60.5 During heart catheterisation
0.581 0.419 0.000
Y60.3 During injection or immunisation
0.581 0.419 0.000
Y60.2 During kidney dialysis or other perfusion
0.581 0.419 0.000
Y60.1 During infusion or transfusion
0.581 0.419 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.580 0.419 0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.580 0.419 0.000
T91.4 Sequelae of injury of intrathoracic organs
0.580 0.419 0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.580 0.419 0.000
G24 Dystonia
0.580 0.420 0.000
Y43 Primarily systemic agents
0.579 0.421 0.000
G00 Bacterial meningitis, not elsewhere classified
0.578 0.422 0.000
F11 Mental and behavioural disorders due to use of opioids
0.577 0.423 0.000
W55 Bitten or struck by other mammals
0.577 0.423 0.000
E65-E68 Obesity and other hyperalimentation
0.577 0.423 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.577 0.423 0.000
E20 Hypoparathyroidism
0.576 0.423 0.000
H93 Other disorders of ear, not elsewhere classified
0.576 0.424 0.000
W99 Exposure to other and unspecified man-made environmental factors
0.574 0.426 0.000
W93 Exposure to excessive cold of man-made origin
0.574 0.426 0.000
W92 Exposure to excessive heat of man-made origin
0.574 0.426 0.000
W91 Exposure to unspecified type of radiation
0.574 0.426 0.000
W90 Exposure to other nonionising radiation
0.574 0.426 0.000
W89 Exposure to man-made visible and ultraviolet light
0.574 0.426 0.000
W88 Exposure to ionising radiation
0.574 0.426 0.000
W87 Exposure to unspecified electric current
0.574 0.426 0.000
W86 Exposure to other specified electric current
0.574 0.426 0.000
W85 Exposure to electric transmission lines
0.574 0.426 0.000
H80 Otosclerosis
0.574 0.426 0.000
Y85 Sequelae of transport accidents
0.573 0.427 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.573 0.427 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.573 0.427 0.000
F69 Unspecified disorder of adult personality and behaviour
0.572 0.428 0.000
G90.2 Horner's syndrome
0.571 0.429 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.571 0.429 0.000
V88 Nontraffic accident of specified type but victim's mode of transport unknown
0.570 0.429 0.000
V87 Traffic accident of specified type but victim's mode of transport unknown
0.570 0.429 0.000
V86 Occupant of special all-terrain or other motor vehicle designed primarily for off-road use, injured in transport accident
0.570 0.429 0.000
V85 Occupant of special construction vehicle injured in transport accident
0.570 0.429 0.000
V84 Occupant of special vehicle mainly used in agriculture injured in transport accident
0.570 0.429 0.000
V83 Occupant of special vehicle mainly used on industrial premises injured in transport accident
0.570 0.429 0.000
V82 Occupant of streetcar injured in transport accident
0.570 0.429 0.000
V81 Occupant of railway train or railway vehicle injured in transport accident
0.570 0.429 0.000
W94.8 Other specified place
0.570 0.430 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.570 0.430 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.569 0.430 0.000
Y54.9 Mineral salts, not elsewhere classified
0.570 0.430 0.000
Y54.7 Agents affecting calcification
0.570 0.430 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.570 0.430 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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