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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs139672165
log Bayes Factor = <0.0001
Chromosome 4   position 138,083,868  (GRCh37) Explore rs139672165 on Ensembl!
Variant rs139672165 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.984 0.016
L03.1 Cellulitis of other parts of limb
0.000 0.993 0.007
D70 Agranulocytosis
0.000 0.995 0.005
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.995 0.005
I25 Chronic ischaemic heart disease
0.000 0.996 0.004
L03 Cellulitis
0.000 0.996 0.004
I25.6 Silent myocardial ischaemia
0.000 0.997 0.003
I25.4 Coronary artery aneurysm
0.000 0.997 0.003
I25.3 Aneurysm of heart
0.000 0.997 0.003
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.997 0.003
L03.0 Cellulitis of finger and toe
0.000 0.997 0.003
L03.2 Cellulitis of face
0.000 0.997 0.003
K81.9 Cholecystitis, unspecified
0.003 0.997 0.000
L03.3 Cellulitis of trunk
0.000 0.997 0.003
M19.99 Arthrosis, unspecified (Site unspecified)
0.000 0.997 0.003
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.997 0.003
I25.5 Ischaemic cardiomyopathy
0.000 0.997 0.002
E21.0 Primary hyperparathyroidism
0.003 0.997 0.000
L03.8 Cellulitis of other sites
0.000 0.997 0.002
L03.9 Cellulitis, unspecified
0.000 0.997 0.002
D73 Diseases of spleen
0.000 0.997 0.002
F31.9 Bipolar affective disorder, unspecified
0.002 0.998 0.000
D75 Other diseases of blood and blood-forming organs
0.000 0.998 0.002
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.998 0.002
D74 Methaemoglobinaemia
0.000 0.998 0.002
D72 Other disorders of white blood cells
0.000 0.998 0.002
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.998 0.002
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.998 0.002
D73.0 Hyposplenism
0.000 0.998 0.002
F31 Bipolar affective disorder
0.002 0.998 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.002 0.998 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.002 0.998 0.000
D73.9 Disease of spleen, unspecified
0.000 0.998 0.002
D73.8 Other diseases of spleen
0.000 0.998 0.002
D73.5 Infarction of spleen
0.000 0.998 0.002
D73.4 Cyst of spleen
0.000 0.998 0.002
D73.3 Abscess of spleen
0.000 0.998 0.002
D73.2 Chronic congestive splenomegaly
0.000 0.998 0.002
D73.1 Hypersplenism
0.000 0.998 0.002
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.002 0.998 0.000
D75.1 Secondary polycythaemia
0.000 0.998 0.002
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.998 0.002
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.998 0.002
D75.2 Essential thrombocytosis
0.000 0.998 0.002
D75.0 Familial erythrocytosis
0.000 0.998 0.002
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.002 0.998 0.000
D41.4 Bladder
0.002 0.998 0.000
D72.9 Disorder of white blood cells, unspecified
0.000 0.998 0.002
D72.8 Other specified disorders of white blood cells
0.000 0.998 0.002
D72.1 Eosinophilia
0.000 0.998 0.002
D72.0 Genetic anomalies of leukocytes
0.000 0.998 0.002
D74.9 Methaemoglobinaemia, unspecified
0.000 0.998 0.002
D74.8 Other methaemoglobinaemias
0.000 0.998 0.002
D74.0 Congenital methaemoglobinaemia
0.000 0.998 0.002
D76.3 Other histiocytosis syndromes
0.000 0.998 0.002
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.998 0.002
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.998 0.002
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.998 0.002
F31.8 Other bipolar affective disorders
0.002 0.998 0.000
F31.7 Bipolar affective disorder, currently in remission
0.002 0.998 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.002 0.998 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.002 0.998 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.002 0.998 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.002 0.998 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.002 0.998 0.000
I25.1 Atherosclerotic heart disease
0.000 0.998 0.002
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.002 0.998 0.000
D41.0 Kidney
0.002 0.998 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.002 0.998 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.002 0.998 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.000 0.998 0.002
D46 Myelodysplastic syndromes
0.002 0.998 0.000
J34.3 Hypertrophy of nasal turbinates
0.000 0.998 0.002
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.001 0.998 0.000
D41.9 Urinary organ, unspecified
0.001 0.998 0.000
D41.7 Other urinary organs
0.001 0.998 0.000
D41.3 Urethra
0.001 0.998 0.000
D41.2 Ureter
0.001 0.998 0.000
D41.1 Renal pelvis
0.001 0.998 0.000
D45 Polycythaemia vera
0.002 0.998 0.000
D17 Benign lipomatous neoplasm
0.002 0.998 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.002 0.998 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.001 0.998 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.001 0.998 0.000
E21.4 Other specified disorders of parathyroid gland
0.001 0.998 0.000
E21.2 Other hyperparathyroidism
0.001 0.998 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.998 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.001 0.998 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.001 0.998 0.000
M25.76 Osteophyte (Lower leg)
0.001 0.999 0.000
C77.1 Intrathoracic lymph nodes
0.000 0.999 0.001
D48.6 Breast
0.001 0.999 0.000
D46.7 Other myelodysplastic syndromes
0.001 0.999 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.001 0.999 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.001 0.999 0.000
D46.4 Refractory anaemia, unspecified
0.001 0.999 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.001 0.999 0.000
D46.2 Refractory anaemia with excess of blasts
0.001 0.999 0.000
D46.1 Refractory anaemia with sideroblasts
0.001 0.999 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.001 0.999 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.001 0.999 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.001 0.999 0.000
E21.3 Hyperparathyroidism, unspecified
0.001 0.999 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.999 0.001
D17.7 Benign lipomatous neoplasm of other sites
0.001 0.999 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.001 0.999 0.000
D47.1 Chronic myeloproliferative disease
0.001 0.999 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.001 0.999 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.001 0.999 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.001 0.999 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.001 0.999 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.001 0.999 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.001 0.999 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.001 0.999 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.001 0.999 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.001 0.999 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.001 0.999 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.001 0.999 0.000
D47.4 Osteomyelofibrosis
0.001 0.999 0.000
D47.2 Monoclonal gammopathy
0.001 0.999 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.001 0.999 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.001 0.999 0.000
D48.7 Other specified sites
0.001 0.999 0.000
D48.5 Skin
0.001 0.999 0.000
D48.4 Peritoneum
0.001 0.999 0.000
D48.3 Retroperitoneum
0.001 0.999 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.001 0.999 0.000
D48.1 Connective and other soft tissue
0.001 0.999 0.000
D48.0 Bone and articular cartilage
0.001 0.999 0.000
J33.9 Nasal polyp, unspecified
0.001 0.999 0.000
K83.1 Obstruction of bile duct
0.000 0.999 0.001
F30-F39 Mood [affective] disorders
0.001 0.999 0.000
F32.0 Mild depressive episode
0.001 0.999 0.000
H40.0 Glaucoma suspect
0.001 0.999 0.000
H40.9 Glaucoma, unspecified
0.001 0.999 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.001 0.999 0.000
K81 Cholecystitis
0.001 0.999 0.000
L04 Acute lymphadenitis
0.000 0.999 0.001
L01 Impetigo
0.000 0.999 0.001
L00 Staphylococcal scalded skin syndrome
0.000 0.999 0.001
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.001 0.999 0.000
D38.6 Respiratory organ, unspecified
0.001 0.999 0.000
D38.5 Other respiratory organs
0.001 0.999 0.000
D38.4 Thymus
0.001 0.999 0.000
D38.3 Mediastinum
0.001 0.999 0.000
D38.2 Pleura
0.001 0.999 0.000
D38.1 Trachea, bronchus and lung
0.001 0.999 0.000
D38.0 Larynx
0.001 0.999 0.000
D39.9 Female genital organ, unspecified
0.001 0.999 0.000
D39.7 Other female genital organs
0.001 0.999 0.000
D39.2 Placenta
0.001 0.999 0.000
D39.1 Ovary
0.001 0.999 0.000
D39.0 Uterus
0.001 0.999 0.000
D40.9 Male genital organ, unspecified
0.001 0.999 0.000
D40.7 Other male genital organs
0.001 0.999 0.000
D40.1 Testis
0.001 0.999 0.000
D40.0 Prostate
0.001 0.999 0.000
D42.9 Meninges, unspecified
0.001 0.999 0.000
D42.1 Spinal meninges
0.001 0.999 0.000
D42.0 Cerebral meninges
0.001 0.999 0.000
D43.9 Central nervous system, unspecified
0.001 0.999 0.000
D43.7 Other parts of central nervous system
0.001 0.999 0.000
D43.4 Spinal cord
0.001 0.999 0.000
D43.3 Cranial nerves
0.001 0.999 0.000
D43.2 Brain, unspecified
0.001 0.999 0.000
D43.1 Brain, infratentorial
0.001 0.999 0.000
D43.0 Brain, supratentorial
0.001 0.999 0.000
D44.9 Endocrine gland, unspecified
0.001 0.999 0.000
D44.8 Pluriglandular involvement
0.001 0.999 0.000
D44.7 Aortic body and other paraganglia
0.001 0.999 0.000
D44.6 Carotid body
0.001 0.999 0.000
D44.5 Pineal gland
0.001 0.999 0.000
D44.4 Craniopharyngeal duct
0.001 0.999 0.000
D44.3 Pituitary gland
0.001 0.999 0.000
D44.2 Parathyroid gland
0.001 0.999 0.000
D44.1 Adrenal gland
0.001 0.999 0.000
D44.0 Thyroid gland
0.001 0.999 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.001 0.999 0.000
K81.0 Acute cholecystitis
0.001 0.999 0.000
L08 Other local infections of skin and subcutaneous tissue
0.000 0.999 0.001
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.999 0.001
D37.9 Digestive organ, unspecified
0.001 0.999 0.000
D37.7 Other digestive organs
0.001 0.999 0.000
D37.6 Liver, gallbladder and bile ducts
0.001 0.999 0.000
D37.4 Colon
0.001 0.999 0.000
D37.3 Appendix
0.001 0.999 0.000
D37.2 Small intestine
0.001 0.999 0.000
D37.1 Stomach
0.001 0.999 0.000
D37.0 Lip, oral cavity and pharynx
0.001 0.999 0.000
F38 Other mood [affective] disorders
0.001 0.999 0.000
F34 Persistent mood [affective] disorders
0.001 0.999 0.000
F32 Depressive episode
0.001 0.999 0.000
F30 Manic episode
0.001 0.999 0.000
F39 Unspecified mood [affective] disorder
0.001 0.999 0.000
F17.2 Dependence syndrome
0.001 0.999 0.000
K83.8 Other specified diseases of biliary tract
0.000 0.999 0.001
M25.72 Osteophyte (Upper arm)
0.001 0.999 0.000
D37.5 Rectum
0.001 0.999 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.001 0.999 0.000
K83.0 Cholangitis
0.000 0.999 0.001
D17.6 Benign lipomatous neoplasm of spermatic cord
0.001 0.999 0.000
E27.1 Primary adrenocortical insufficiency
0.001 0.999 0.000
K81.8 Other cholecystitis
0.001 0.999 0.000
L01.1 Impetiginisation of other dermatoses
0.000 0.999 0.001
L01.0 Impetigo [any organism] [any site]
0.000 0.999 0.001
L04.9 Acute lymphadenitis, unspecified
0.000 0.999 0.001
L04.8 Acute lymphadenitis of other sites
0.000 0.999 0.001
L04.3 Acute lymphadenitis of lower limb
0.000 0.999 0.001
L04.2 Acute lymphadenitis of upper limb
0.000 0.999 0.001
L04.1 Acute lymphadenitis of trunk
0.000 0.999 0.001
L04.0 Acute lymphadenitis of face, head and neck
0.000 0.999 0.001
L05 Pilonidal cyst
0.000 0.999 0.001
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.999 0.001
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.999 0.001
L08.1 Erythrasma
0.000 0.999 0.001
L08.0 Pyoderma
0.000 0.999 0.001
O34.2 Maternal care due to uterine scar from previous surgery
0.000 0.999 0.001
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.001 0.999 0.000
Z30.2 Sterilisation
0.000 0.999 0.001
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.001 0.999 0.000
F30.9 Manic episode, unspecified
0.001 0.999 0.000
F30.8 Other manic episodes
0.001 0.999 0.000
F30.2 Mania with psychotic symptoms
0.001 0.999 0.000
F30.1 Mania without psychotic symptoms
0.001 0.999 0.000
F30.0 Hypomania
0.001 0.999 0.000
F32.8 Other depressive episodes
0.001 0.999 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.001 0.999 0.000
F34.8 Other persistent mood [affective] disorders
0.001 0.999 0.000
F34.1 Dysthymia
0.001 0.999 0.000
F34.0 Cyclothymia
0.001 0.999 0.000
F38.8 Other specified mood [affective] disorders
0.001 0.999 0.000
F38.1 Other recurrent mood [affective] disorders
0.001 0.999 0.000
F38.0 Other single mood [affective] disorders
0.001 0.999 0.000
J31.0 Chronic rhinitis
0.001 0.999 0.000
F33 Recurrent depressive disorder
0.001 0.999 0.000
D50.8 Other iron deficiency anaemias
0.000 0.999 0.001
E23.0 Hypopituitarism
0.001 0.999 0.000
L05.0 Pilonidal cyst with abscess
0.000 0.999 0.001
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.999 0.001
N73.6 Female pelvic peritoneal adhesions
0.000 0.999 0.001
E27 Other disorders of adrenal gland
0.001 0.999 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.001 0.999 0.000
F32.1 Moderate depressive episode
0.001 0.999 0.000
F40.2 Specific (isolated) phobias
0.001 0.999 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.000 0.999 0.001
M25.71 Osteophyte (Shoulder region)
0.001 0.999 0.000
S42.20 Fracture of upper end of humerus (closed)
0.001 0.999 0.000
F33.8 Other recurrent depressive disorders
0.001 0.999 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.001 0.999 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.001 0.999 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.001 0.999 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.001 0.999 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.001 0.999 0.000
F80.1 Expressive language disorder
0.001 0.999 0.000
N02.9 Unspecified
0.001 0.999 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.999 0.000
E27.8 Other specified disorders of adrenal gland
0.001 0.999 0.000
E27.5 Adrenomedullary hyperfunction
0.001 0.999 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.999 0.000
E27.2 Addisonian crisis
0.001 0.999 0.000
E27.0 Other adrenocortical overactivity
0.001 0.999 0.000
M25.7 Osteophyte
0.001 0.999 0.000
E23 Hypofunction and other disorders of pituitary gland
0.001 0.999 0.000
K83 Other diseases of biliary tract
0.000 0.999 0.001
S72.00 Fracture of neck of femur (closed)
0.001 0.999 0.000
C77.9 Lymph node, unspecified
0.000 0.999 0.001
H02.4 Ptosis of eyelid
0.000 0.999 0.001
Z60.2 Living alone
0.000 0.999 0.001
M25.79 Osteophyte (Site unspecified)
0.001 0.999 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.001 0.999 0.000
M25.74 Osteophyte (Hand)
0.001 0.999 0.000
M25.73 Osteophyte (Forearm)
0.001 0.999 0.000
M25.70 Osteophyte (Multiple sites)
0.001 0.999 0.000
C77.2 Intra-abdominal lymph nodes
0.000 0.999 0.001
E23.7 Disorder of pituitary gland, unspecified
0.001 0.999 0.000
E23.6 Other disorders of pituitary gland
0.001 0.999 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.999 0.000
E23.2 Diabetes insipidus
0.001 0.999 0.000
E23.1 Drug-induced hypopituitarism
0.001 0.999 0.000
K83.9 Disease of biliary tract, unspecified
0.000 0.999 0.001
K83.5 Biliary cyst
0.000 0.999 0.001
K83.4 Spasm of sphincter of Oddi
0.000 0.999 0.001
K83.3 Fistula of bile duct
0.000 0.999 0.001
K83.2 Perforation of bile duct
0.000 0.999 0.001
E20-E35 Disorders of other endocrine glands
0.001 0.999 0.000
C77.5 Intrapelvic lymph nodes
0.000 0.999 0.001
I25.2 Old myocardial infarction
0.000 0.999 0.001
L05.9 Pilonidal cyst without abscess
0.000 0.999 0.001
O04.9 Complete or unspecified, without complication
0.000 0.999 0.001
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.000 0.999 0.001
S66 Injury of muscle and tendon at wrist and hand level
0.001 0.999 0.000
Q07.0 Arnold-Chiari syndrome
0.001 0.999 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.001 0.999 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.001 0.999 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.001 0.999 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.001 0.999 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.001 0.999 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.001 0.999 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.001 0.999 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.001 0.999 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.001 0.999 0.000
E34 Other endocrine disorders
0.001 0.999 0.000
E32 Diseases of thymus
0.001 0.999 0.000
E31 Polyglandular dysfunction
0.001 0.999 0.000
E30 Disorders of puberty, not elsewhere classified
0.001 0.999 0.000
E29 Testicular dysfunction
0.001 0.999 0.000
E28 Ovarian dysfunction
0.001 0.999 0.000
E26 Hyperaldosteronism
0.001 0.999 0.000
E25 Adrenogenital disorders
0.001 0.999 0.000
E24 Cushing's syndrome
0.001 0.999 0.000
E22 Hyperfunction of pituitary gland
0.001 0.999 0.000
E20 Hypoparathyroidism
0.001 0.999 0.000
M25.78 Osteophyte (Other)
0.001 0.999 0.000
E20.9 Hypoparathyroidism, unspecified
0.001 0.999 0.000
E20.8 Other hypoparathyroidism
0.001 0.999 0.000
E20.1 Pseudohypoparathyroidism
0.001 0.999 0.000
E20.0 Idiopathic hypoparathyroidism
0.001 0.999 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.001 0.999 0.000
E22.8 Other hyperfunction of pituitary gland
0.001 0.999 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.001 0.999 0.000
E22.1 Hyperprolactinaemia
0.001 0.999 0.000
E22.0 Acromegaly and pituitary gigantism
0.001 0.999 0.000
E24.9 Cushing's syndrome, unspecified
0.001 0.999 0.000
E24.8 Other Cushing's syndrome
0.001 0.999 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.999 0.000
E24.3 Ectopic ACTH syndrome
0.001 0.999 0.000
E24.2 Drug-induced Cushing's syndrome
0.001 0.999 0.000
E24.1 Nelson's syndrome
0.001 0.999 0.000
E24.0 Pituitary-dependent Cushing's disease
0.001 0.999 0.000
E25.9 Adrenogenital disorder, unspecified
0.001 0.999 0.000
E25.8 Other adrenogenital disorders
0.001 0.999 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.999 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.999 0.000
E26.8 Other hyperaldosteronism
0.001 0.999 0.000
E26.1 Secondary hyperaldosteronism
0.001 0.999 0.000
E26.0 Primary hyperaldosteronism
0.001 0.999 0.000
E28.9 Ovarian dysfunction, unspecified
0.001 0.999 0.000
E28.8 Other ovarian dysfunction
0.001 0.999 0.000
E28.3 Primary ovarian failure
0.001 0.999 0.000
E28.2 Polycystic ovarian syndrome
0.001 0.999 0.000
E28.1 Androgen excess
0.001 0.999 0.000
E28.0 Oestrogen excess
0.001 0.999 0.000
E29.9 Testicular dysfunction, unspecified
0.001 0.999 0.000
E29.8 Other testicular dysfunction
0.001 0.999 0.000
E29.1 Testicular hypofunction
0.001 0.999 0.000
E29.0 Testicular hyperfunction
0.001 0.999 0.000
E30.9 Disorder of puberty, unspecified
0.001 0.999 0.000
E30.8 Other disorders of puberty
0.001 0.999 0.000
E30.1 Precocious puberty
0.001 0.999 0.000
E30.0 Delayed puberty
0.001 0.999 0.000
E31.9 Polyglandular dysfunction, unspecified
0.001 0.999 0.000
E31.8 Other polyglandular dysfunction
0.001 0.999 0.000
E31.1 Polyglandular hyperfunction
0.001 0.999 0.000
E31.0 Autoimmune polyglandular failure
0.001 0.999 0.000
E32.9 Disease of thymus, unspecified
0.001 0.999 0.000
E32.8 Other diseases of thymus
0.001 0.999 0.000
E32.1 Abscess of thymus
0.001 0.999 0.000
E32.0 Persistent hyperplasia of thymus
0.001 0.999 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.999 0.000
E34.8 Other specified endocrine disorders
0.001 0.999 0.000
E34.5 Androgen resistance syndrome
0.001 0.999 0.000
E34.4 Constitutional tall stature
0.001 0.999 0.000
E34.3 Short stature, not elsewhere classified
0.001 0.999 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.999 0.000
E34.1 Other hypersecretion of intestinal hormones
0.001 0.999 0.000
E34.0 Carcinoid syndrome
0.001 0.999 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.001 0.999 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.001 0.999 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.001 0.999 0.000
F33.9 Recurrent depressive disorder, unspecified
0.001 0.999 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.001 0.999 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.999 0.001
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.999 0.001
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.999 0.001
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.001 0.999 0.000
C77.8 Lymph nodes of multiple regions
0.000 0.999 0.001
C77.4 Inguinal and lower limb lymph nodes
0.000 0.999 0.001
C78.7 Secondary malignant neoplasm of liver
0.000 0.999 0.001
K11.2 Sialoadenitis
0.001 0.999 0.000
N48.6 Balanitis xerotica obliterans
0.001 0.999 0.000
Y43.3 Other antineoplastic drugs
0.000 0.999 0.001
M43.19 Spondylolisthesis (Site unspecified)
0.001 0.999 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.001 0.999 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.001 0.999 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.001 0.999 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.001 0.999 0.000
M43.12 Spondylolisthesis (Cervical region)
0.001 0.999 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.001 0.999 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.001 0.999 0.000
C25.9 Pancreas, unspecified
0.000 0.999 0.001
E11.3 With ophthalmic complications
0.000 0.999 0.001
J30.1 Allergic rhinitis due to pollen
0.001 0.999 0.000
J33.1 Polypoid sinus degeneration
0.001 0.999 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.999 0.001
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.999 0.001
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.999 0.001
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.999 0.001
M43.1 Spondylolisthesis
0.001 0.999 0.000
J33 Nasal polyp
0.001 0.999 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.999 0.001
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.999 0.001
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.999 0.001
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.999 0.001
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.999 0.001
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.999 0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.999 0.001
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.999 0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.999 0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.001 0.999 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.001 0.999 0.000
F80.9 Developmental disorder of speech and language, unspecified
0.001 0.999 0.000
F80.8 Other developmental disorders of speech and language
0.001 0.999 0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]
0.001 0.999 0.000
F80.2 Receptive language disorder
0.001 0.999 0.000
F80.0 Specific speech articulation disorder
0.001 0.999 0.000
H40.8 Other glaucoma
0.001 0.999 0.000
H40.6 Glaucoma secondary to drugs
0.001 0.999 0.000
H40.5 Glaucoma secondary to other eye disorders
0.001 0.999 0.000
H40.4 Glaucoma secondary to eye inflammation
0.001 0.999 0.000
H40.3 Glaucoma secondary to eye trauma
0.001 0.999 0.000
H54.7 Unspecified visual loss
0.001 0.999 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.999 0.001
H40 Glaucoma
0.001 0.999 0.000
M25.56 Pain in joint (Lower leg)
0.000 0.999 0.001
M25.77 Osteophyte (Ankle and foot)
0.001 0.999 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.001 0.999 0.000
H18.5 Hereditary corneal dystrophies
0.001 0.999 0.000
L30.9 Dermatitis, unspecified
0.000 0.999 0.001
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.000 0.999 0.001
T51.0 Ethanol
0.001 0.999 0.000
F80 Specific developmental disorders of speech and language
0.001 0.999 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.001 0.999 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.001 0.999 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.001 0.999 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.001 0.999 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.001 0.999 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.001 0.999 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.001 0.999 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.001 0.999 0.000
F17.9 Unspecified mental and behavioural disorder
0.001 0.999 0.000
F17.8 Other mental and behavioural disorders
0.001 0.999 0.000
F17.7 Residual and late-onset psychotic disorder
0.001 0.999 0.000
F17.6 Amnesic syndrome
0.001 0.999 0.000
F17.5 Psychotic disorder
0.001 0.999 0.000
F17.4 Withdrawal state with delirium
0.001 0.999 0.000
F17.3 Withdrawal state
0.001 0.999 0.000
F17.0 Acute intoxication
0.001 0.999 0.000
J33.8 Other polyp of sinus
0.001 0.999 0.000
J33.0 Polyp of nasal cavity
0.001 0.999 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.999 0.001
N02.8 Other
0.001 0.999 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.001 0.999 0.000
S42.21 Fracture of upper end of humerus (open)
0.001 0.999 0.000
S72.01 Fracture of neck of femur (open)
0.001 0.999 0.000
I63.9 Cerebral infarction, unspecified
0.001 0.999 0.000
J31.2 Chronic pharyngitis
0.001 0.999 0.000
J31.1 Chronic nasopharyngitis
0.001 0.999 0.000
K82.1 Hydrops of gallbladder
0.001 0.999 0.000
L43.9 Lichen planus, unspecified
0.000 0.999 0.001
M23.8 Other internal derangements of knee
0.001 0.999 0.000
O03.9 Complete or unspecified, without complication
0.000 0.999 0.001
F17 Mental and behavioural disorders due to use of tobacco
0.001 0.999 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.001 0.999 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.001 0.999 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.001 0.999 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.001 0.999 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.999 0.001
F40.9 Phobic anxiety disorder, unspecified
0.001 0.999 0.000
F40.8 Other phobic anxiety disorders
0.001 0.999 0.000
F40.1 Social phobias
0.001 0.999 0.000
F40.0 Agoraphobia
0.001 0.999 0.000
J38.0 Paralysis of vocal cords and larynx
0.001 0.999 0.000
K55.9 Vascular disorder of intestine, unspecified
0.001 0.999 0.000
K81.1 Chronic cholecystitis
0.001 0.999 0.000
M75.1 Rotator cuff syndrome
0.000 0.999 0.001
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.001 0.999 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.001 0.999 0.000
M25.51 Pain in joint (Shoulder region)
0.000 0.999 0.001
M81.98 Osteoporosis, unspecified (Other)
0.001 0.999 0.000
C77.0 Lymph nodes of head, face and neck
0.000 0.999 0.001
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.999 0.001
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.999 0.001
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.999 0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.999 0.001
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.999 0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.999 0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.999 0.001
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.999 0.001
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.999 0.001
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.999 0.001
D81.9 Combined immunodeficiency, unspecified
0.000 0.999 0.001
D81.8 Other combined immunodeficiencies
0.000 0.999 0.001
D81.7 Major histocompatibility complex class II deficiency
0.000 0.999 0.001
D81.6 Major histocompatibility complex class I deficiency
0.000 0.999 0.001
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.999 0.001
D81.4 Nezelof's syndrome
0.000 0.999 0.001
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.999 0.001
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.999 0.001
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.999 0.001
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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