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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1412829
log Bayes Factor = 154.353
Chromosome 9   position 22,043,926  (GRCh37) Explore rs1412829 on Ensembl!
Variant rs1412829 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H40.9 Glaucoma, unspecified
0.000 0.000 1.000
H40.1 Primary open-angle glaucoma
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
C71 Malignant neoplasm of brain
1.000 0.000 0.000
H40 Glaucoma
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.000 1.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.000 1.000
I74 Arterial embolism and thrombosis
0.000 0.000 1.000
C71.9 Brain, unspecified
1.000 0.000 0.000
I73 Other peripheral vascular diseases
0.000 0.000 1.000
I22 Subsequent myocardial infarction
0.000 0.001 0.999
I21.4 Acute subendocardial myocardial infarction
0.000 0.001 0.999
C44 Other malignant neoplasms of skin
0.999 0.001 0.000
C71.1 Frontal lobe
0.998 0.002 0.000
C44.3 Skin of other and unspecified parts of face
0.997 0.003 0.000
I77 Other disorders of arteries and arterioles
0.000 0.003 0.997
I77.1 Stricture of artery
0.000 0.003 0.997
Chapter IX Diseases of the circulatory system
0.000 0.006 0.994
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.008 0.992
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.009 0.991
C44.5 Skin of trunk
0.991 0.009 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.011 0.989
I24 Other acute ischaemic heart diseases
0.000 0.013 0.987
I60-I69 Cerebrovascular diseases
0.000 0.013 0.987
H40.0 Glaucoma suspect
0.000 0.021 0.979
C71.3 Parietal lobe
0.979 0.021 0.000
C44.0 Skin of lip
0.972 0.028 0.000
I72 Other aneurysm
0.000 0.029 0.971
I67 Other cerebrovascular diseases
0.000 0.034 0.966
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.035 0.965
C44.1 Skin of eyelid, including canthus
0.961 0.039 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.961 0.039 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.043 0.957
C43-C44 Melanoma and other malignant neoplasms of skin
0.951 0.049 0.000
C15 Malignant neoplasm of oesophagus
0.951 0.049 0.000
C15-C26 Malignant neoplasms of digestive organs
0.948 0.052 0.000
E11.9 Without complications
0.000 0.056 0.944
C15.9 Oesophagus, unspecified
0.943 0.057 0.000
C15.5 Lower third of oesophagus
0.941 0.059 0.000
Chapter II Neoplasms
0.941 0.059 0.000
I67.9 Cerebrovascular disease, unspecified
0.000 0.064 0.936
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.067 0.933
C71.0 Cerebrum, except lobes and ventricles
0.924 0.076 0.000
I24.8 Other forms of acute ischaemic heart disease
0.000 0.076 0.924
I25.5 Ischaemic cardiomyopathy
0.000 0.077 0.923
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.080 0.920
I20.8 Other forms of angina pectoris
0.000 0.080 0.920
C16 Malignant neoplasm of stomach
0.919 0.081 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.081 0.919
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.083 0.917
C71.2 Temporal lobe
0.916 0.084 0.000
C71.8 Overlapping lesion of brain
0.912 0.088 0.000
H40.8 Other glaucoma
0.000 0.096 0.904
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.098 0.902
C16.0 Cardia
0.897 0.103 0.000
I72.3 Aneurysm of iliac artery
0.000 0.103 0.897
I25.4 Coronary artery aneurysm
0.000 0.106 0.894
I70 Atherosclerosis
0.000 0.108 0.892
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.113 0.887
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.115 0.885
E78.0 Pure hypercholesterolaemia
0.000 0.117 0.883
C44.4 Skin of scalp and neck
0.879 0.121 0.000
Z95.3 Presence of xenogenic heart valve
0.000 0.123 0.877
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.125 0.875
I60 Subarachnoid haemorrhage
0.000 0.135 0.865
C44.2 Skin of ear and external auricular canal
0.832 0.168 0.000
I62 Other nontraumatic intracranial haemorrhage
0.000 0.171 0.829
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.176 0.824
I22.8 Subsequent myocardial infarction of other sites
0.000 0.179 0.821
C21 Malignant neoplasm of anus and anal canal
0.820 0.180 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.816 0.184 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.193 0.807
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.200 0.800
I72.0 Aneurysm of carotid artery
0.000 0.201 0.799
C17 Malignant neoplasm of small intestine
0.798 0.202 0.000
H40.2 Primary angle-closure glaucoma
0.000 0.203 0.797
C71.5 Cerebral ventricle
0.794 0.206 0.000
C16.9 Stomach, unspecified
0.789 0.211 0.000
I67.2 Cerebral atherosclerosis
0.000 0.211 0.789
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.212 0.788
I25.3 Aneurysm of heart
0.000 0.213 0.787
E11 Non-insulin-dependent diabetes mellitus
0.000 0.215 0.785
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.216 0.784
I72.9 Aneurysm of unspecified site
0.000 0.222 0.777
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.776 0.224 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.226 0.774
I74.8 Embolism and thrombosis of other arteries
0.000 0.231 0.769
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.240 0.760
C44.6 Skin of upper limb, including shoulder
0.760 0.240 0.000
I72.4 Aneurysm of artery of lower extremity
0.000 0.243 0.757
E11.1 With ketoacidosis
0.000 0.251 0.749
I72.2 Aneurysm of renal artery
0.000 0.256 0.744
I70.1 Atherosclerosis of renal artery
0.000 0.261 0.739
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.262 0.738
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.262 0.738
C16.5 Lesser curvature of stomach, unspecified
0.732 0.268 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.731 0.269 0.000
I77.0 Arteriovenous fistula, acquired
0.000 0.274 0.726
I25.6 Silent myocardial ischaemia
0.000 0.277 0.723
D00-D09 In situ neoplasms
0.721 0.279 0.000
C23 Malignant neoplasm of gallbladder
0.721 0.279 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.280 0.720
C21.8 Overlapping lesion of rectum, anus and anal canal
0.720 0.280 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.281 0.719
C71.6 Cerebellum
0.717 0.283 0.000
H40.6 Glaucoma secondary to drugs
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
C15.0 Cervical part of oesophagus
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.716 0.284 0.000
I77.5 Necrosis of artery
0.000 0.285 0.715
I77.4 Coeliac artery compression syndrome
0.000 0.285 0.715
I77.3 Arterial fibromuscular dysplasia
0.000 0.285 0.715
C16.8 Overlapping lesion of stomach
0.710 0.290 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.291 0.709
C15.3 Upper third of oesophagus
0.701 0.299 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.302 0.698
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.697 0.303 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.304 0.696
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.304 0.696
I72.1 Aneurysm of artery of upper extremity
0.000 0.304 0.696
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.307 0.693
I67.5 Moyamoya disease
0.000 0.307 0.693
I67.4 Hypertensive encephalopathy
0.000 0.307 0.693
I67.3 Progressive vascular leukoencephalopathy
0.000 0.307 0.693
I72.8 Aneurysm of other specified arteries
0.000 0.307 0.693
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.308 0.692
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.308 0.692
C20 Malignant neoplasm of rectum
0.689 0.311 0.000
C71.4 Occipital lobe
0.688 0.312 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.687 0.312 0.000
H40.3 Glaucoma secondary to eye trauma
0.000 0.313 0.687
C69 Malignant neoplasm of eye and adnexa
0.685 0.315 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.316 0.684
C15.8 Overlapping lesion of oesophagus
0.682 0.318 0.000
C15.2 Abdominal part of oesophagus
0.682 0.318 0.000
C15.1 Thoracic part of oesophagus
0.682 0.318 0.000
C21.0 Anus, unspecified
0.679 0.321 0.000
C16.6 Greater curvature of stomach, unspecified
0.674 0.326 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.327 0.673
I00-I02 Acute rheumatic fever
0.000 0.330 0.670
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.330 0.669
C40-C41 Malignant neoplasms of bone and articular cartilage
0.668 0.332 0.000
D05 Carcinoma in situ of breast
0.667 0.333 0.000
I60.8 Other subarachnoid haemorrhage
0.000 0.335 0.665
C02 Malignant neoplasm of other and unspecified parts of tongue
0.664 0.336 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.339 0.661
E11.4 With neurological complications
0.000 0.342 0.658
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.343 0.657
C71.7 Brain stem
0.657 0.343 0.000
C17.0 Duodenum
0.657 0.343 0.000
I70.9 Generalised and unspecified atherosclerosis
0.000 0.347 0.653
I61 Intracerebral haemorrhage
0.000 0.348 0.652
C16.1 Fundus of stomach
0.649 0.351 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.351 0.648
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.352 0.648
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.352 0.648
Z92.2 Personal history of long-term (current) use of other medicaments
0.000 0.353 0.647
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.353 0.647
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.355 0.645
I70.8 Atherosclerosis of other arteries
0.000 0.357 0.643
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.643 0.357 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.641 0.359 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.361 0.638
E11.5 With peripheral circulatory complications
0.000 0.362 0.638
D02 Carcinoma in situ of middle ear and respiratory system
0.637 0.363 0.000
Z95.0 Presence of cardiac pacemaker
0.000 0.366 0.634
I65.1 Occlusion and stenosis of basilar artery
0.000 0.367 0.633
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.370 0.630
D05.9 Carcinoma in situ of breast, unspecified
0.628 0.372 0.000
I23 Certain current complications following acute myocardial infarction
0.000 0.373 0.627
C17.9 Small intestine, unspecified
0.620 0.380 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.380 0.620
H40.4 Glaucoma secondary to eye inflammation
0.000 0.384 0.616
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.616 0.384 0.000
C03 Malignant neoplasm of gum
0.616 0.384 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.610 0.390 0.000
D05.7 Other carcinoma in situ of breast
0.610 0.390 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.392 0.608
I62.1 Nontraumatic extradural haemorrhage
0.000 0.393 0.607
I24.1 Dressler's syndrome
0.000 0.395 0.605
I74.5 Embolism and thrombosis of iliac artery
0.000 0.398 0.602
C17.2 Ileum
0.601 0.399 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.403 0.597
E11.8 With unspecified complications
0.000 0.405 0.595
C16.4 Pylorus
0.594 0.406 0.000
C07 Malignant neoplasm of parotid gland
0.592 0.408 0.000
I79.1 Aortitis in diseases classified elsewhere
0.000 0.409 0.591
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.409 0.591
C02.9 Tongue, unspecified
0.589 0.411 0.000
C21.2 Cloacogenic zone
0.588 0.412 0.000
I67.1 Cerebral aneurysm, nonruptured
0.000 0.412 0.588
E11.0 With coma
0.000 0.418 0.582
C70 Malignant neoplasm of meninges
0.581 0.419 0.000
C11 Malignant neoplasm of nasopharynx
0.580 0.420 0.000
C00 Malignant neoplasm of lip
0.577 0.423 0.000
C24.0 Extrahepatic bile duct
0.574 0.426 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.426 0.574
C17.8 Overlapping lesion of small intestine
0.572 0.427 0.000
C17.3 Meckel's diverticulum
0.572 0.427 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.430 0.570
D09 Carcinoma in situ of other and unspecified sites
0.569 0.431 0.000
D04 Carcinoma in situ of skin
0.567 0.433 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.435 0.565
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.435 0.565
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.435 0.565
C31 Malignant neoplasm of accessory sinuses
0.562 0.437 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.438 0.562
C38 Malignant neoplasm of heart, mediastinum and pleura
0.558 0.442 0.000
D02.0 Larynx
0.553 0.447 0.000
C17.1 Jejunum
0.552 0.448 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.550 0.450 0.000
C16.2 Body of stomach
0.548 0.452 0.000
C14.0 Pharynx, unspecified
0.548 0.452 0.000
H40.5 Glaucoma secondary to other eye disorders
0.000 0.452 0.548
C30.0 Nasal cavity
0.548 0.452 0.000
C10 Malignant neoplasm of oropharynx
0.546 0.454 0.000
C13 Malignant neoplasm of hypopharynx
0.544 0.456 0.000
D04.3 Skin of other and unspecified parts of face
0.543 0.457 0.000
C69.9 Eye, unspecified
0.542 0.458 0.000
E11.6 With other specified complications
0.000 0.461 0.539
C06 Malignant neoplasm of other and unspecified parts of mouth
0.535 0.465 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.534 0.465 0.000
C24.9 Biliary tract, unspecified
0.534 0.466 0.000
E11.7 With multiple complications
0.000 0.467 0.533
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.469 0.531
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.470 0.530
C05 Malignant neoplasm of palate
0.530 0.470 0.000
C69.2 Retina
0.528 0.472 0.000
C08.9 Major salivary gland, unspecified
0.528 0.472 0.000
I77.2 Rupture of artery
0.000 0.473 0.527
C24.8 Overlapping lesion of biliary tract
0.524 0.476 0.000
C37 Malignant neoplasm of thymus
0.524 0.476 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.477 0.523
C24.1 Ampulla of Vater
0.516 0.484 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.484 0.515
C03.9 Gum, unspecified
0.515 0.485 0.000
C04 Malignant neoplasm of floor of mouth
0.512 0.488 0.000
D02.2 Bronchus and lung
0.507 0.492 0.000
Z82.3 Family history of stroke
0.000 0.493 0.507
C02.4 Lingual tonsil
0.503 0.497 0.000
C69.6 Orbit
0.501 0.498 0.000
C01 Malignant neoplasm of base of tongue
0.501 0.499 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.499 0.500 0.000
C33 Malignant neoplasm of trachea
0.499 0.500 0.000
D04.2 Skin of ear and external auricular canal
0.498 0.502 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.502 0.498
C69.0 Conjunctiva
0.495 0.505 0.000
C72.9 Central nervous system, unspecified
0.493 0.507 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.493 0.507 0.000
C72.5 Other and unspecified cranial nerves
0.493 0.507 0.000
C72.4 Acoustic nerve
0.493 0.507 0.000
C72.3 Optic nerve
0.493 0.507 0.000
C72.2 Olfactory nerve
0.493 0.507 0.000
C72.1 Cauda equina
0.493 0.507 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.493 0.507 0.000
D09.0 Bladder
0.492 0.508 0.000
C72.0 Spinal cord
0.492 0.508 0.000
C69.8 Overlapping lesion of eye and adnexa
0.491 0.509 0.000
C69.5 Lachrymal gland and duct
0.491 0.509 0.000
C69.4 Ciliary body
0.491 0.509 0.000
C69.1 Cornea
0.491 0.509 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.488 0.512 0.001
C08.0 Submandibular gland
0.488 0.512 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.517 0.483
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.517 0.483
I02 Rheumatic chorea
0.000 0.519 0.480
I01 Rheumatic fever with heart involvement
0.000 0.519 0.480
I70.0 Atherosclerosis of aorta
0.000 0.520 0.479
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.479 0.521 0.000
C02.8 Overlapping lesion of tongue
0.476 0.524 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.476 0.524 0.000
C02.0 Dorsal surface of tongue
0.476 0.524 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.475 0.525 0.000
C21.1 Anal canal
0.472 0.528 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.529 0.471
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.529 0.471
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.529 0.471
C02.2 Ventral surface of tongue
0.470 0.530 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.531 0.468
C31.0 Maxillary sinus
0.466 0.534 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.535 0.464
D04.0 Skin of lip
0.463 0.537 0.000
C48.0 Retroperitoneum
0.461 0.539 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.539 0.461
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.461 0.539 0.000
C14.2 Waldeyer's ring
0.461 0.539 0.000
C08.8 Overlapping lesion of major salivary glands
0.460 0.540 0.000
C08.1 Sublingual gland
0.460 0.540 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.001 0.540 0.459
D02.4 Respiratory system, unspecified
0.457 0.543 0.000
D02.3 Other parts of respiratory system
0.457 0.543 0.000
D02.1 Trachea
0.457 0.543 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.456 0.544 0.000
C03.0 Upper gum
0.455 0.545 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.547 0.453
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.549 0.451
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.550 0.450
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.550 0.450
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.550 0.450
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.550 0.450
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.550 0.450
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.550 0.450
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.550 0.450
C26 Malignant neoplasm of other and ill-defined digestive organs
0.449 0.551 0.000
D01.2 Rectum
0.444 0.556 0.000
C46 Kaposi's sarcoma
0.442 0.558 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.559 0.441
C11.9 Nasopharynx, unspecified
0.439 0.561 0.000
I00 Rheumatic fever without mention of heart involvement
0.000 0.562 0.438
C30.1 Middle ear
0.437 0.563 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.434 0.566 0.000
C38.4 Pleura
0.434 0.566 0.000
C02.1 Border of tongue
0.434 0.566 0.000
C16.3 Pyloric antrum
0.431 0.568 0.001
C38.3 Mediastinum, part unspecified
0.431 0.569 0.000
C00.1 External lower lip
0.431 0.569 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.570 0.429
C00.0 External upper lip
0.429 0.571 0.000
E11.2 With renal complications
0.000 0.575 0.425
D09.9 Carcinoma in situ, unspecified
0.424 0.576 0.000
C15.4 Middle third of oesophagus
0.423 0.577 0.000
I20.1 Angina pectoris with documented spasm
0.000 0.577 0.423
C12 Malignant neoplasm of pyriform sinus
0.422 0.578 0.000
I68.0 Cerebral amyloid angiopathy
0.000 0.579 0.421
H40-H42 Glaucoma
0.000 0.582 0.418
C60-C63 Malignant neoplasms of male genital organs
0.417 0.583 0.000
C70.9 Meninges, unspecified
0.416 0.583 0.000
C70.1 Spinal meninges
0.416 0.583 0.000
C48.2 Peritoneum, unspecified
0.416 0.584 0.000
C11.8 Overlapping lesion of nasopharynx
0.416 0.584 0.000
C11.3 Anterior wall of nasopharynx
0.416 0.584 0.000
C11.2 Lateral wall of nasopharynx
0.416 0.584 0.000
C11.1 Posterior wall of nasopharynx
0.416 0.584 0.000
C11.0 Superior wall of nasopharynx
0.416 0.584 0.000
C00.8 Overlapping lesion of lip
0.414 0.586 0.000
C00.6 Commissure of lip
0.414 0.586 0.000
C00.5 Lip, unspecified, inner aspect
0.414 0.586 0.000
C00.4 Lower lip, inner aspect
0.414 0.586 0.000
C00.3 Upper lip, inner aspect
0.414 0.586 0.000
C00.2 External lip, unspecified
0.414 0.586 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.588 0.412
C13.0 Postcricoid region
0.410 0.590 0.000
D09.3 Thyroid and other endocrine glands
0.408 0.592 0.000
D09.2 Eye
0.408 0.592 0.000
D04.8 Skin of other sites
0.407 0.593 0.000
D04.4 Skin of scalp and neck
0.407 0.593 0.000
D01.0 Colon
0.405 0.595 0.000
I71 Aortic aneurysm and dissection
0.000 0.596 0.404
C31.9 Accessory sinus, unspecified
0.403 0.597 0.000
C31.8 Overlapping lesion of accessory sinuses
0.403 0.597 0.000
C31.3 Sphenoidal sinus
0.403 0.597 0.000
C31.2 Frontal sinus
0.403 0.597 0.000
C31.1 Ethmoidal sinus
0.403 0.597 0.000
C06.0 Cheek mucosa
0.403 0.597 0.000
D09.7 Carcinoma in situ of other specified sites
0.403 0.597 0.000
C00.9 Lip, unspecified
0.403 0.597 0.000
C50-C50 Malignant neoplasm of breast
0.403 0.597 0.000
C03.1 Lower gum
0.401 0.599 0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.400 0.600 0.000
C38.2 Posterior mediastinum
0.400 0.600 0.000
C38.1 Anterior mediastinum
0.400 0.600 0.000
C38.0 Heart
0.400 0.600 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.398 0.602 0.000
C05.9 Palate, unspecified
0.395 0.605 0.000
D01.9 Digestive organ, unspecified
0.395 0.605 0.000
D01.7 Other specified digestive organs
0.395 0.605 0.000
D01.5 Liver, gallbladder and bile ducts
0.395 0.605 0.000
D01.4 Other and unspecified parts of intestine
0.395 0.605 0.000
D01.1 Rectosigmoid junction
0.395 0.605 0.000
C10.8 Overlapping lesion of oropharynx
0.392 0.608 0.000
C10.4 Branchial cleft
0.392 0.608 0.000
C10.3 Posterior wall of oropharynx
0.392 0.608 0.000
C10.2 Lateral wall of oropharynx
0.392 0.608 0.000
C10.1 Anterior surface of epiglottis
0.392 0.608 0.000
C10.0 Vallecula
0.392 0.608 0.000
D06 Carcinoma in situ of cervix uteri
0.392 0.608 0.000
C13.8 Overlapping lesion of hypopharynx
0.390 0.610 0.000
C13.2 Posterior wall of hypopharynx
0.390 0.610 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.390 0.610 0.000
D04.9 Skin, unspecified
0.389 0.611 0.000
C09 Malignant neoplasm of tonsil
0.387 0.613 0.001
C32 Malignant neoplasm of larynx
0.386 0.613 0.000
C41.4 Pelvic bones, sacrum and coccyx
0.386 0.614 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.616 0.383
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.383 0.617 0.000
C06.1 Vestibule of mouth
0.383 0.617 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.383 0.617 0.000
C10.9 Oropharynx, unspecified
0.382 0.618 0.000
C64-C68 Malignant neoplasms of urinary tract
0.382 0.618 0.000
C48.1 Specified parts of peritoneum
0.381 0.619 0.000
C05.8 Overlapping lesion of palate
0.380 0.620 0.000
C05.2 Uvula
0.380 0.620 0.000
C05.1 Soft palate
0.375 0.624 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.625 0.375
D04.1 Skin of eyelid, including canthus
0.374 0.626 0.000
C47.1 Peripheral nerves of upper limb, including shoulder
0.373 0.626 0.000
C06.2 Retromolar area
0.371 0.629 0.000
C04.8 Overlapping lesion of floor of mouth
0.367 0.633 0.000
C04.1 Lateral floor of mouth
0.367 0.633 0.000
D05.0 Lobular carcinoma in situ
0.367 0.633 0.000
C41.9 Bone and articular cartilage, unspecified
0.365 0.634 0.000
Z82.1 Family history of blindness and visual loss
0.000 0.634 0.365
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.365 0.635 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.637 0.363
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.637 0.363
I23.8 Other current complications following acute myocardial infarction
0.000 0.640 0.360
C04.0 Anterior floor of mouth
0.358 0.642 0.000
C39.9 Ill-defined sites within the respiratory system
0.358 0.642 0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.358 0.642 0.000
C39.0 Upper respiratory tract, part unspecified
0.358 0.642 0.000
D01.3 Anus and anal canal
0.358 0.642 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.001 0.642 0.357
C41.1 Mandible
0.356 0.644 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.646 0.354
C41.8 Overlapping lesion of bone and articular cartilage
0.354 0.646 0.000
C41.3 Ribs, sternum and clavicle
0.354 0.646 0.000
C13.9 Hypopharynx, unspecified
0.352 0.648 0.000
C06.9 Mouth, unspecified
0.351 0.649 0.000
E10-E14 Diabetes mellitus
0.000 0.654 0.346
Z82.2 Family history of deafness and hearing loss
0.000 0.655 0.345
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.655 0.345
I01.8 Other acute rheumatic heart disease
0.000 0.655 0.345
I01.2 Acute rheumatic myocarditis
0.000 0.655 0.345
I01.1 Acute rheumatic endocarditis
0.000 0.655 0.345
I01.0 Acute rheumatic pericarditis
0.000 0.655 0.345
I02.9 Rheumatic chorea without heart involvement
0.000 0.655 0.345
I02.0 Rheumatic chorea with heart involvement
0.000 0.655 0.345
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.656 0.344
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.343 0.656 0.000
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.343 0.656 0.000
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.343 0.656 0.000
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.343 0.656 0.000
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.343 0.656 0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.340 0.659 0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.340 0.659 0.000
C47.6 Peripheral nerves of trunk, unspecified
0.340 0.659 0.000
C47.5 Peripheral nerves of pelvis
0.340 0.659 0.000
C47.4 Peripheral nerves of abdomen
0.340 0.659 0.000
C47.3 Peripheral nerves of thorax
0.340 0.659 0.000
C47.2 Peripheral nerves of lower limb, including hip
0.340 0.659 0.000
C47.0 Peripheral nerves of head, face and neck
0.340 0.659 0.000
C05.0 Hard palate
0.339 0.661 0.000
C41.2 Vertebral column
0.339 0.661 0.000
C60 Malignant neoplasm of penis
0.337 0.663 0.000
C04.9 Floor of mouth, unspecified
0.334 0.665 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.667 0.333
C69.3 Choroid
0.329 0.670 0.000
C41.0 Bones of skull and face
0.329 0.670 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.329 0.671 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.327 0.671 0.001
Z95.2 Presence of prosthetic heart valve
0.000 0.672 0.328
C40.9 Bone and articular cartilage of limb, unspecified
0.327 0.673 0.000
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.327 0.673 0.000
C40.3 Short bones of lower limb
0.327 0.673 0.000
C40.1 Short bones of upper limb
0.327 0.673 0.000
I77.8 Other specified disorders of arteries and arterioles
0.001 0.674 0.325
I61.8 Other intracerebral haemorrhage
0.000 0.675 0.325
C26.8 Overlapping lesion of digestive system
0.322 0.678 0.000
C26.1 Spleen
0.322 0.678 0.000
D09.1 Other and unspecified urinary organs
0.321 0.678 0.000
C65 Malignant neoplasm of renal pelvis
0.320 0.680 0.000
C46.9 Kaposi's sarcoma, unspecified
0.317 0.683 0.000
C46.8 Kaposi's sarcoma of multiple organs
0.317 0.683 0.000
C46.7 Kaposi's sarcoma of other sites
0.317 0.683 0.000
C46.3 Kaposi's sarcoma of lymph nodes
0.317 0.683 0.000
C46.2 Kaposi's sarcoma of palate
0.317 0.683 0.000
C46.1 Kaposi's sarcoma of soft tissue
0.317 0.683 0.000
C46.0 Kaposi's sarcoma of skin
0.317 0.683 0.000
C40.0 Scapula and long bones of upper limb
0.316 0.683 0.000
C40.2 Long bones of lower limb
0.315 0.685 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.689 0.311
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.691 0.309
C70.0 Cerebral meninges
0.308 0.691 0.001
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.691 0.309
H42 Glaucoma in diseases classified elsewhere
0.000 0.700 0.300
C63 Malignant neoplasm of other and unspecified male genital organs
0.299 0.701 0.000
C49.0 Connective and soft tissue of head, face and neck
0.294 0.706 0.000
D06.0 Endocervix
0.293 0.707 0.000
I69 Sequelae of cerebrovascular disease
0.000 0.708 0.292
D05.1 Intraductal carcinoma in situ
0.292 0.708 0.000
E14 Unspecified diabetes mellitus
0.000 0.710 0.290
C09.1 Tonsillar pillar (anterior) (posterior)
0.290 0.710 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.710 0.290
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.710 0.290

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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