TreeWAS – Variant ID: rs141958207

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XV Pregnancy, childbirth and the puerperium	0.673	0.327
# Top node	0.671	0.329
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.668	0.332
Chapter VIII Diseases of the ear and mastoid process	0.666	0.334
O60-O75 Complications of labour and delivery	0.663	0.337
Chapter VI Diseases of the nervous system	0.655	0.345
I20-I25 Ischaemic heart diseases	0.643	0.357
Chapter IX Diseases of the circulatory system	0.641	0.359
H65-H75 Diseases of middle ear and mastoid	0.639	0.361
G40-G47 Episodic and paroxysmal disorders	0.638	0.362
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.633	0.367
O68 Labour and delivery complicated by foetal stress [distress]	0.626	0.374
I25 Chronic ischaemic heart disease	0.626	0.374
O63 Long labour	0.619	0.381
I25.2 Old myocardial infarction	0.618	0.382
I21 Acute myocardial infarction	0.607	0.393
T36-T50 Poisoning by drugs, medicaments and biological substances	0.601	0.399
G45 Transient cerebral ischaemic attacks and related syndromes	0.601	0.399
H90-H95 Other disorders of ear	0.585	0.415
S00-S09 Injuries to the head	0.583	0.417
O63.1 Prolonged second stage (of labour)	0.579	0.421
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.577	0.423
G45.9 Transient cerebral ischaemic attack, unspecified	0.574	0.426
S60-S69 Injuries to the wrist and hand	0.573	0.427
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.570	0.430
I21.1 Acute transmural myocardial infarction of inferior wall	0.562	0.438
S50-S59 Injuries to the elbow and forearm	0.561	0.439
H60-H62 Diseases of external ear	0.559	0.441
H65 Nonsuppurative otitis media	0.556	0.444
S20-S29 Injuries to the thorax	0.556	0.444
H71 Cholesteatoma of middle ear	0.553	0.446
I25.8 Other forms of chronic ischaemic heart disease	0.552	0.448
Chapter VII Diseases of the eye and adnexa	0.549	0.451
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.546	0.454
I21.0 Acute transmural myocardial infarction of anterior wall	0.539	0.461
O48 Prolonged pregnancy	0.536	0.464
O32 Maternal care for known or suspected malpresentation of foetus	0.531	0.469
H80-H83 Diseases of inner ear	0.529	0.471
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.527	0.473
I20 Angina pectoris	0.524	0.476
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.523	0.476
G30-G32 Other degenerative diseases of the nervous system	0.518	0.481
G35-G37 Demyelinating diseases of the central nervous system	0.514	0.486
O66 Other obstructed labour	0.513	0.487
G20-G26 Extrapyramidal and movement disorders	0.512	0.488
Chapter V Mental and behavioural disorders	0.511	0.489
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.510	0.490
G47 Sleep disorders	0.508	0.492
O46 Antepartum haemorrhage, not elsewhere classified	0.506	0.494
H72 Perforation of tympanic membrane	0.504	0.496
G44 Other headache syndromes	0.504	0.496
S06 Intracranial injury	0.503	0.497
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.502	0.498
O75 Other complications of labour and delivery, not elsewhere classified	0.501	0.498
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.501	0.499
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.499	0.501
G40 Epilepsy	0.499	0.501
G43 Migraine	0.497	0.503
O72 Postpartum haemorrhage	0.495	0.504
S66 Injury of muscle and tendon at wrist and hand level	0.495	0.505
H73 Other disorders of tympanic membrane	0.494	0.506
O80-O84 Delivery	0.493	0.507
I60-I69 Cerebrovascular diseases	0.492	0.508
O47 False labour	0.491	0.509
G90-G99 Other disorders of the nervous system	0.491	0.509
H66 Suppurative and unspecified otitis media	0.491	0.509
O20-O29 Other maternal disorders predominantly related to pregnancy	0.491	0.509
S32 Fracture of lumbar spine and pelvis	0.491	0.509
O94-O99 Other obstetric conditions, not elsewhere classified	0.491	0.509
S70-S79 Injuries to the hip and thigh	0.490	0.509
H65.9 Nonsuppurative otitis media, unspecified	0.490	0.510
T66-T78 Other and unspecified effects of external causes	0.489	0.511
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.489	0.511
I20.0 Unstable angina	0.486	0.514
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.485	0.515
S52 Fracture of forearm	0.485	0.515
Chapter XXII Codes for special purposes	0.483	0.517
H61 Other disorders of external ear	0.483	0.517
O85-O92 Complications predominantly related to the puerperium	0.482	0.518
O63.0 Prolonged first stage (of labour)	0.482	0.518
Chapter XVI Certain conditions originating in the perinatal period	0.481	0.519
I22 Subsequent myocardial infarction	0.480	0.520
T79-T79 Certain early complications of trauma	0.479	0.521
T33-T35 Frostbite	0.479	0.521
T26-T28 Burns and corrosions confined to eye and internal organs	0.479	0.521
T20-T25 Burns and corrosions of external body surface, specified by site	0.479	0.521
T15-T19 Effects of foreign body entering through natural orifice	0.479	0.521
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.479	0.521
T00-T07 Injuries involving multiple body regions	0.479	0.521
S90-S99 Injuries to the ankle and foot	0.479	0.521
S10-S19 Injuries to the neck	0.479	0.521
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.478	0.522
S80-S89 Injuries to the knee and lower leg	0.476	0.524
O74 Complications of anaesthesia during labour and delivery	0.476	0.524
O73 Retained placenta and membranes, without haemorrhage	0.476	0.524
O71 Other obstetric trauma	0.476	0.524
O69 Labour and delivery complicated by umbilical cord complications	0.476	0.524
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.476	0.524
O65 Obstructed labour due to maternal pelvic abnormality	0.476	0.524
O64 Obstructed labour due to malposition and malpresentation of foetus	0.476	0.524
O62 Abnormalities of forces of labour	0.476	0.524
O61 Failed induction of labour	0.476	0.524
O60 Preterm delivery	0.476	0.524
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.475	0.524
G70-G73 Diseases of myoneural junction and muscle	0.470	0.530
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.470	0.530
G00-G09 Inflammatory diseases of the central nervous system	0.470	0.530
H91 Other hearing loss	0.468	0.531
O42 Premature rupture of membranes	0.466	0.534
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.465	0.535
Chapter XX External causes of morbidity and mortality	0.465	0.535
S01 Open wound of head	0.464	0.536
I05-I09 Chronic rheumatic heart diseases	0.464	0.536
I23 Certain current complications following acute myocardial infarction	0.461	0.539
T39.1 4-Aminophenol derivatives	0.460	0.540
S40-S49 Injuries to the shoulder and upper arm	0.460	0.540
I00-I02 Acute rheumatic fever	0.460	0.540
O36 Maternal care for other known or suspected foetal problems	0.459	0.541
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.458	0.541
H74 Other disorders of middle ear and mastoid	0.458	0.541
H70 Mastoiditis and related conditions	0.458	0.541
H69 Other disorders of Eustachian tube	0.458	0.541
H68 Eustachian salpingitis and obstruction	0.458	0.541
H67 Otitis media in diseases classified elsewhere	0.458	0.541
H93 Other disorders of ear, not elsewhere classified	0.458	0.542
O32.1 Maternal care for breech presentation	0.458	0.542
G46 Vascular syndromes of brain in cerebrovascular diseases	0.458	0.542
G41 Status epilepticus	0.458	0.542
O34 Maternal care for known or suspected abnormality of pelvic organs	0.456	0.544
I24 Other acute ischaemic heart diseases	0.456	0.544
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.455	0.545
H92 Otalgia and effusion of ear	0.455	0.545
O45 Premature separation of placenta [abruptio placentae]	0.454	0.546
O44 Placenta praevia	0.454	0.546
O43 Placental disorders	0.454	0.546
O41 Other disorders of amniotic fluid and membranes	0.454	0.546
O35 Maternal care for known or suspected foetal abnormality and damage	0.454	0.546
O33 Maternal care for known or suspected disproportion	0.454	0.546
O31 Complications specific to multiple gestation	0.454	0.546
O30 Multiple gestation	0.454	0.546
O40 Polyhydramnios	0.454	0.546
H40-H42 Glaucoma	0.452	0.548
H90 Conductive and sensorineural hearing loss	0.449	0.551
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.449	0.551
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.449	0.551
I25.6 Silent myocardial ischaemia	0.449	0.551
I25.5 Ischaemic cardiomyopathy	0.449	0.551
I25.4 Coronary artery aneurysm	0.449	0.551
I25.3 Aneurysm of heart	0.449	0.551
I25.0 Atherosclerotic cardiovascular disease, so described	0.449	0.551
I21.4 Acute subendocardial myocardial infarction	0.447	0.553
S60 Superficial injury of wrist and hand	0.446	0.554
G80-G83 Cerebral palsy and other paralytic syndromes	0.446	0.554
S29 Other and unspecified injuries of thorax	0.444	0.556
O63.9 Long labour, unspecified	0.444	0.556
O63.2 Delayed delivery of second twin, triplet, etc.	0.444	0.556
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.444	0.556
O00-O08 Pregnancy with abortive outcome	0.444	0.556
I70-I79 Diseases of arteries, arterioles and capillaries	0.440	0.560
S02 Fracture of skull and facial bones	0.438	0.562
I21.X Presumed acute myicardial infaction (unconfirmed)	0.436	0.564
I21.3 Acute transmural myocardial infarction of unspecified site	0.436	0.564
I21.2 Acute transmural myocardial infarction of other sites	0.436	0.564
S62 Fracture at wrist and hand level	0.435	0.564
S00 Superficial injury of head	0.435	0.565
I95-I99 Other and unspecified disorders of the circulatory system	0.432	0.568
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.431	0.569
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.431	0.569
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.431	0.569
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.431	0.569
T46 Poisoning by agents primarily affecting the cardiovascular system	0.431	0.569
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.431	0.569
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.431	0.569
T41 Poisoning by anaesthetics and therapeutic gases	0.431	0.569
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.431	0.569
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.431	0.569
T36 Poisoning by systemic antibiotics	0.431	0.569
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.431	0.569
G45.4 Transient global amnesia	0.431	0.569
G45.3 Amaurosis fugax	0.431	0.569
G45.2 Multiple and bilateral precerebral artery syndromes	0.431	0.569
G45.1 Carotid artery syndrome (hemispheric)	0.431	0.569
G45.0 Vertebro-basilar artery syndrome	0.431	0.569
Chapter XXI Factors influencing health status and contact with health services	0.429	0.571
S27 Injury of other and unspecified intrathoracic organs	0.427	0.573
H81 Disorders of vestibular function	0.424	0.576
T42.4 Benzodiazepines	0.423	0.577
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.421	0.579
T93 Sequelae of injuries of lower limb	0.420	0.580
H43-H45 Disorders of vitreous body and globe	0.420	0.580
S52.5 Fracture of lower end of radius	0.420	0.580
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.420	0.580
H94 Other disorders of ear in diseases classified elsewhere	0.420	0.580
G47.3 Sleep apnoea	0.419	0.581
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.419	0.581
S08 Traumatic amputation of part of head	0.418	0.582
S07 Crushing injury of head	0.418	0.582
S05 Injury of eye and orbit	0.418	0.582
S04 Injury of cranial nerves	0.418	0.582
S03 Dislocation, sprain and strain of joints and ligaments of head	0.418	0.582
S22 Fracture of rib(s), sternum and thoracic spine	0.418	0.582
H65.3 Chronic mucoid otitis media	0.415	0.585
S06.5 Traumatic subdural haemorrhage	0.415	0.585
O46.9 Antepartum haemorrhage, unspecified	0.415	0.585
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.414	0.586
S37 Injury of urinary and pelvic organs	0.414	0.586
S36 Injury of intra-abdominal organs	0.414	0.586
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.414	0.586
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.414	0.586
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.414	0.586
S31 Open wound of abdomen, lower back and pelvis	0.414	0.586
S30 Superficial injury of abdomen, lower back and pelvis	0.414	0.586
S64 Injury of nerves at wrist and hand level	0.413	0.587
G35 Multiple sclerosis	0.412	0.588
Chapter XII Diseases of the skin and subcutaneous tissue	0.412	0.588
S69 Other and unspecified injuries of wrist and hand	0.411	0.589
S68 Traumatic amputation of wrist and hand	0.411	0.589
S67 Crushing injury of wrist and hand	0.411	0.589
S65 Injury of blood vessels at wrist and hand level	0.411	0.589
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.411	0.589
H02 Other disorders of eyelid	0.411	0.589
S06.2 Diffuse brain injury	0.409	0.591
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.409	0.591
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.409	0.591
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.408	0.592
O70 Perineal laceration during delivery	0.408	0.592
H72.9 Perforation of tympanic membrane, unspecified	0.407	0.593
W00-W19 Falls	0.407	0.593
G44.2 Tension-type headache	0.407	0.593
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.406	0.594
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.405	0.595
S32.0 Fracture of lumbar vertebra	0.404	0.596
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.403	0.597
H00 Hordeolum and chalazion	0.403	0.597
F00-F09 Organic, including symptomatic, mental disorders	0.403	0.597
S59 Other and unspecified injuries of forearm	0.402	0.597
S58 Traumatic amputation of forearm	0.402	0.597
S57 Crushing injury of forearm	0.402	0.597
S56 Injury of muscle and tendon at forearm level	0.402	0.597
S55 Injury of blood vessels at forearm level	0.402	0.597
S54 Injury of nerves at forearm level	0.402	0.597
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.402	0.597
S51 Open wound of forearm	0.402	0.597
S50 Superficial injury of forearm	0.402	0.597
Chapter X Diseases of the respiratory system	0.402	0.598
H62 Disorders of external ear in diseases classified elsewhere	0.401	0.599
H60 Otitis externa	0.401	0.599
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.401	0.599
I27 Other pulmonary heart diseases	0.401	0.599
H65.4 Other chronic nonsuppurative otitis media	0.399	0.601
H65.2 Chronic serous otitis media	0.399	0.601
H65.1 Other acute nonsuppurative otitis media	0.399	0.601
H65.0 Acute serous otitis media	0.399	0.601
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.398	0.601
S26 Injury of heart	0.398	0.601
S25 Injury of blood vessels of thorax	0.398	0.601
S24 Injury of nerves and spinal cord at thorax level	0.398	0.601
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.398	0.601
S21 Open wound of thorax	0.398	0.601
S20 Superficial injury of thorax	0.398	0.601
H61.0 Perichondritis of external ear	0.398	0.602
J30-J39 Other diseases of upper respiratory tract	0.395	0.605
Q20-Q28 Congenital malformations of the circulatory system	0.395	0.605
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.394	0.606
H61.2 Impacted cerumen	0.394	0.606
H55-H59 Other disorders of eye and adnexa	0.393	0.607
H46-H48 Disorders of optic nerve and visual pathways	0.393	0.607
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.393	0.607
H10-H13 Disorders of conjunctiva	0.393	0.607
S32.5 Fracture of pubis	0.392	0.608
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.392	0.608
O72.0 Third-stage haemorrhage	0.392	0.608
G25 Other extrapyramidal and movement disorders	0.391	0.609
G43.1 Migraine with aura [classical migraine]	0.391	0.609
H73.8 Other specified disorders of tympanic membrane	0.390	0.610
G20 Parkinson's disease	0.390	0.610
O47.1 False labour at or after 37 completed weeks of gestation	0.390	0.610
H83 Other diseases of inner ear	0.389	0.610
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.389	0.610
I67 Other cerebrovascular diseases	0.387	0.613
I63 Cerebral infarction	0.386	0.613
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.386	0.614
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.385	0.614
G96 Other disorders of central nervous system	0.385	0.615
H66.9 Otitis media, unspecified	0.385	0.615
H91.9 Hearing loss, unspecified	0.385	0.615
T31 Burns classified according to extent of body surface involved	0.383	0.617
H40 Glaucoma	0.382	0.618
O32.9 Maternal care for malpresentation of foetus, unspecified	0.381	0.619
O32.8 Maternal care for other malpresentation of foetus	0.381	0.619
O32.6 Maternal care for compound presentation	0.381	0.619
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.381	0.619
O32.4 Maternal care for high head at term	0.381	0.619
O32.3 Maternal care for face, brow and chin presentation	0.381	0.619
O32.2 Maternal care for transverse and oblique lie	0.381	0.619
O32.0 Maternal care for unstable lie	0.381	0.619
F30-F39 Mood [affective] disorders	0.381	0.619
H80 Otosclerosis	0.379	0.620
H82 Vertiginous syndromes in diseases classified elsewhere	0.379	0.620
W20-W49 Exposure to inanimate mechanical forces	0.378	0.621
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.378	0.622
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.378	0.622
T39.4 Antirheumatics, not elsewhere classified	0.378	0.622
T39.2 Pyrazolone derivatives	0.378	0.622
T39.0 Salicylates	0.378	0.622
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.375	0.624
I20.1 Angina pectoris with documented spasm	0.375	0.624
T98 Sequelae of other and unspecified effects of external causes	0.375	0.624
T95 Sequelae of burns, corrosions and frostbite	0.375	0.624
T94 Sequelae of injuries involving multiple and unspecified body regions	0.375	0.624
T92 Sequelae of injuries of upper limb	0.375	0.624
T91 Sequelae of injuries of neck and trunk	0.375	0.624
T90 Sequelae of injuries of head	0.375	0.624
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.375	0.624
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.375	0.624
J33 Nasal polyp	0.373	0.627
S52.50 Fracture of lower end of radius (closed)	0.373	0.627
I20.8 Other forms of angina pectoris	0.372	0.628
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.372	0.628
G30 Alzheimer's disease	0.372	0.628
S01.1 Open wound of eyelid and periocular area	0.371	0.629
Z37 Outcome of delivery	0.370	0.630
S52.6 Fracture of lower end of both ulna and radius	0.369	0.630
G37 Other demyelinating diseases of central nervous system	0.368	0.631
G36 Other acute disseminated demyelination	0.368	0.631
G93 Other disorders of brain	0.368	0.632
O66.9 Obstructed labour, unspecified	0.368	0.632
O66.8 Other specified obstructed labour	0.368	0.632
O66.4 Failed trial of labour, unspecified	0.368	0.632
O66.3 Obstructed labour due to other abnormalities of foetus	0.368	0.632
O66.2 Obstructed labour due to unusually large foetus	0.368	0.632
O66.1 Obstructed labour due to locked twins	0.368	0.632
O66.0 Obstructed labour due to shoulder dystocia	0.368	0.632
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.368	0.632
H93.1 Tinnitus	0.367	0.632
G24 Dystonia	0.367	0.633
G23 Other degenerative diseases of basal ganglia	0.367	0.633
G21 Secondary Parkinsonism	0.367	0.633
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.367	0.633
G22 Parkinsonism in diseases classified elsewhere	0.367	0.633
H02.3 Blepharochalasis	0.367	0.633
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.367	0.633
F99-F99 Unspecified mental disorder	0.367	0.633
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.367	0.633
F80-F89 Disorders of psychological development	0.367	0.633
F70-F79 Mental retardation	0.367	0.633
F60-F69 Disorders of adult personality and behaviour	0.367	0.633
G50-G59 Nerve, nerve root and plexus disorders	0.367	0.633
S09 Other and unspecified injuries of head	0.366	0.634
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.366	0.634
Q80-Q89 Other congenital malformations	0.366	0.634
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.366	0.634
Q60-Q64 Congenital malformations of the urinary system	0.366	0.634
Q50-Q56 Congenital malformations of genital organs	0.366	0.634
Q38-Q45 Other congenital malformations of the digestive system	0.366	0.634
Q35-Q37 Cleft lip and cleft palate	0.366	0.634
Q30-Q34 Congenital malformations of the respiratory system	0.366	0.634
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.366	0.634
Q00-Q07 Congenital malformations of the nervous system	0.366	0.634
W19 Unspecified fall	0.366	0.634
G47.8 Other sleep disorders	0.365	0.635
G47.4 Narcolepsy and cataplexy	0.365	0.635
G47.2 Disorders of the sleep-wake schedule	0.365	0.635
G47.1 Disorders of excessive somnolence [hypersomnias]	0.365	0.635
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.365	0.635
S29.9 Unspecified injury of thorax	0.365	0.635
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.364	0.635
G43.9 Migraine, unspecified	0.364	0.636
O80 Single spontaneous delivery	0.364	0.636
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.363	0.636
S72 Fracture of femur	0.363	0.636
O36.5 Maternal care for poor foetal growth	0.363	0.636
O26 Maternal care for other conditions predominantly related to pregnancy	0.363	0.637
G40.9 Epilepsy, unspecified	0.363	0.637
O46.8 Other antepartum haemorrhage	0.363	0.637
O46.0 Antepartum haemorrhage with coagulation defect	0.363	0.637
I22.9 Subsequent myocardial infarction of unspecified site	0.363	0.637
O16 Unspecified maternal hypertension	0.363	0.637
Chapter I Certain infectious and parasitic diseases	0.362	0.638
H72.8 Other perforations of tympanic membrane	0.362	0.638
H72.2 Other marginal perforations of tympanic membrane	0.362	0.638
H72.1 Attic perforation of tympanic membrane	0.362	0.638
H72.0 Central perforation of tympanic membrane	0.362	0.638
S01.2 Open wound of nose	0.361	0.639
G44.8 Other specified headache syndromes	0.361	0.639
G44.4 Drug-induced headache, not elsewhere classified	0.361	0.639
G44.3 Chronic posttraumatic headache	0.361	0.639
G44.1 Vascular headache, not elsewhere classified	0.361	0.639
G44.0 Cluster headache syndrome	0.361	0.639
T78 Adverse effects, not elsewhere classified	0.361	0.639
H92.0 Otalgia	0.361	0.639
S06.9 Intracranial injury, unspecified	0.361	0.639
S06.8 Other intracranial injuries	0.361	0.639
S06.7 Intracranial injury with prolonged coma	0.361	0.639
S06.6 Traumatic subarachnoid haemorrhage	0.361	0.639
S06.4 Epidural haemorrhage	0.361	0.639
S06.3 Focal brain injury	0.361	0.639
S06.1 Traumatic cerebral oedema	0.361	0.639
S06.0 Concussion	0.361	0.639
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.360	0.639
I61 Intracerebral haemorrhage	0.360	0.640
T32 Corrosions classified according to extent of body surface involved	0.360	0.640
T30 Burn and corrosion, body region unspecified	0.360	0.640
T29 Burns and corrosions of multiple body regions	0.360	0.640
O75.9 Complication of labour and delivery, unspecified	0.360	0.640
O75.8 Other specified complications of labour and delivery	0.360	0.640
O75.7 Vaginal delivery following previous Caesarean section	0.360	0.640
O75.5 Delayed delivery after artificial rupture of membranes	0.360	0.640
O75.4 Other complications of obstetric surgery and procedures	0.360	0.640
O75.3 Other infection during labour	0.360	0.640
O75.2 Pyrexia during labour, not elsewhere classified	0.360	0.640
O75.1 Shock during or following labour and delivery	0.360	0.640
O75.0 Maternal distress during labour and delivery	0.360	0.640
O15 Eclampsia	0.359	0.640
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.359	0.640
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.359	0.640
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.359	0.640
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.359	0.640
G47.9 Sleep disorder, unspecified	0.359	0.641
H01 Other inflammation of eyelid	0.358	0.642
H04 Disorders of lachrymal system	0.358	0.642
S61 Open wound of wrist and hand	0.358	0.642
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.358	0.642
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.358	0.642
T42.5 Mixed antiepileptics, not elsewhere classified	0.358	0.642
T42.3 Barbiturates	0.358	0.642
T42.2 Succinimides and oxazolidinediones	0.358	0.642
T42.1 Iminostilbenes	0.358	0.642
T42.0 Hydantoin derivatives	0.358	0.642
G40.8 Other epilepsy	0.357	0.642
G40.7 Petit mal, unspecified, without grand mal seizures	0.357	0.642
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.357	0.642
G40.5 Special epileptic syndromes	0.357	0.642
G40.4 Other generalised epilepsy and epileptic syndromes	0.357	0.642
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.357	0.642
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.357	0.642
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.357	0.642
G43.8 Other migraine	0.357	0.643
G43.3 Complicated migraine	0.357	0.643
G43.2 Status migrainosus	0.357	0.643
G43.0 Migraine without aura [common migraine]	0.357	0.643
G91 Hydrocephalus	0.356	0.644
O72.3 Postpartum coagulation defects	0.355	0.645
O72.2 Delayed and secondary postpartum haemorrhage	0.355	0.645
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.355	0.645
S66.8 Injury of other muscles and tendons at wrist and hand level	0.355	0.645
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.355	0.645
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.355	0.645
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.355	0.645
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.355	0.645
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.355	0.645
S60.8 Other superficial injuries of wrist and hand	0.355	0.645
H73.9 Disorder of tympanic membrane, unspecified	0.354	0.646
H73.1 Chronic myringitis	0.354	0.646
H73.0 Acute myringitis	0.354	0.646
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.353	0.646
O84 Multiple delivery	0.353	0.647
O83 Other assisted single delivery	0.353	0.647
O82 Single delivery by Caesarean section	0.353	0.647
O81 Single delivery by forceps and vacuum extractor	0.353	0.647
I68 Cerebrovascular disorders in diseases classified elsewhere	0.353	0.647
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.353	0.647
I62 Other nontraumatic intracranial haemorrhage	0.353	0.647
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.353	0.647
O47.9 False labour, unspecified	0.352	0.647
O47.0 False labour before 37 completed weeks of gestation	0.352	0.647
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.352	0.647
G95 Other diseases of spinal cord	0.352	0.647
G94 Other disorders of brain in diseases classified elsewhere	0.352	0.647
G90 Disorders of autonomic nervous system	0.352	0.647
G98 Other disorders of nervous system, not elsewhere classified	0.352	0.647
G92 Toxic encephalopathy	0.352	0.647
H66.4 Suppurative otitis media, unspecified	0.352	0.648
H66.3 Other chronic suppurative otitis media	0.352	0.648
H66.2 Chronic atticoantral suppurative otitis media	0.352	0.648
H66.1 Chronic tubotympanic suppurative otitis media	0.352	0.648
H66.0 Acute suppurative otitis media	0.352	0.648
O29 Complications of anaesthesia during pregnancy	0.352	0.648
O28 Abnormal findings on antenatal screening of mother	0.352	0.648
O24 Diabetes mellitus in pregnancy	0.352	0.648
O23 Infections of genito-urinary tract in pregnancy	0.352	0.648
O22 Venous complications in pregnancy	0.352	0.648
O21 Excessive vomiting in pregnancy	0.352	0.648
O25 Malnutrition in pregnancy	0.352	0.648
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.352	0.648
S32.7 Multiple fractures of lumbar spine and pelvis	0.352	0.648
S32.4 Fracture of acetabulum	0.352	0.648
S32.3 Fracture of ilium	0.352	0.648
S32.2 Fracture of coccyx	0.352	0.648
S32.1 Fracture of sacrum	0.352	0.648
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.352	0.648
O97 Death from sequelae of direct obstetric causes	0.352	0.648
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.352	0.648
O95 Obstetric death of unspecified cause	0.352	0.648
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.352	0.648
G63 Polyneuropathy in diseases classified elsewhere	0.352	0.648
S79 Other and unspecified injuries of hip and thigh	0.352	0.648
S78 Traumatic amputation of hip and thigh	0.352	0.648
S77 Crushing injury of hip and thigh	0.352	0.648
S76 Injury of muscle and tendon at hip and thigh level	0.352	0.648

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations